ENTRY R00320 Reaction NAME diphosphate:acetate phosphotransferase DEFINITION Diphosphate + Acetate <=> Orthophosphate + Acetyl phosphate EQUATION C00013 + C00033 <=> C00009 + C00227 RCLASS RC00043 C00033_C00227 ENZYME 2.7.2.12 PATHWAY rn00620 Pyruvate metabolism rn01100 Metabolic pathways BRITE Enzymatic reactions [BR:br08201] 2. Transferase reactions 2.7 Transferring phosphorus-containing groups 2.7.2 Phosphotransferases with a carboxy group as acceptor 2.7.2.12 R00320 Diphosphate + Acetate <=> Orthophosphate + Acetyl phosphate DBLINKS RHEA: 24279 /// ENTRY R11947 Reaction DEFINITION S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite EQUATION C21787 + C00001 <=> C00051 + C00094 COMMENT spontaneous the second step of two-step reaction (see R08678, R11946+R11947) RCLASS RC03147 C00051_C21787 ENZYME 1.13.11.18 BRITE Enzymatic reactions [BR:br08201] 1. Oxidoreductase reactions 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) 1.13.11 With incorporation of two atoms of oxygen 1.13.11.18 R11947 S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite DBLINKS RHEA: 28658 /// ENTRY R07252 Reaction NAME acetyl-CoA:taxan-10beta-ol O-acetyltransferase DEFINITION Acetyl-CoA + 10-Desacetyltaxuyunnanin C <=> CoA + Taxuyunnanin C EQUATION C00024 + C15538 <=> C00010 + C15537 RCLASS RC00004 C00010_C00024 RC00055 C15537_C15538 ENZYME 2.3.1.163 BRITE Enzymatic reactions [BR:br08201] 2. Transferase reactions 2.3 Acyltransferases 2.3.1 Transferring groups other than aminoacyl groups 2.3.1.163 R07252 Acetyl-CoA + 10-Desacetyltaxuyunnanin C <=> CoA + Taxuyunnanin C DBLINKS RHEA: 18840 /// ENTRY R09400 Reaction NAME L-glutamate:coenzyme F420-1 ligase (GDP-forming) DEFINITION Coenzyme F420-1 + GTP + L-Glutamate <=> Coenzyme F420 + GDP + Orthophosphate EQUATION C19152 + C00044 + C00025 <=> C00876 + C00035 + C00009 RCLASS RC00002 C00035_C00044 RC00064 C00025_C00876 RC00090 C00876_C19152 ENZYME 6.3.2.34 PATHWAY rn00680 Methane metabolism rn01100 Metabolic pathways rn01120 Microbial metabolism in diverse environments rn01240 Biosynthesis of cofactors MODULE M00378 F420 biosynthesis, archaea BRITE Enzymatic reactions [BR:br08201] 6. Ligase reactions 6.3 Forming carbon-nitrogen bonds 6.3.2 Acid-D-amino-acid ligases (peptide synthases) 6.3.2.34 R09400 Coenzyme F420-1 + GTP + L-Glutamate <=> Coenzyme F420 + GDP + Orthophosphate ORTHOLOGY K12234 coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] K24998 dehydro coenzyme F420 reductase / coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:1.3.8.17 6.3.2.31 6.3.2.34] /// ENTRY R00460 Reaction NAME lysine racemase DEFINITION L-Lysine <=> D-Lysine EQUATION C00047 <=> C00739 RCLASS RC00302 C00047_C00739 ENZYME 5.1.1.5 5.1.1.10 PATHWAY rn00310 Lysine degradation rn00470 D-Amino acid metabolism rn01100 Metabolic pathways rn01120 Microbial metabolism in diverse environments MODULE M00960 Lysine degradation, bacteria, L-lysine => D-lysine => succinate BRITE Enzymatic reactions [BR:br08201] 5. Isomerase reactions 5.1 Racemases and epimerases 5.1.1 Acting on amino acids and derivatives 5.1.1.5 R00460 L-Lysine <=> D-Lysine 5.1.1.10 R00460 L-Lysine <=> D-Lysine IUBMB reaction hierarchy [BR:br08202] 5. Isomerase reactions 5.1.1.10 R01265 L-Amino acid <=> D-Amino acid R00460 L-Lysine <=> D-Lysine ORTHOLOGY K25316 amino-acid racemase [EC:5.1.1.10] K25317 amino-acid racemase [EC:5.1.1.10] DBLINKS RHEA: 22867 /// ENTRY R11942 Reaction NAME oleuropein 2-beta-D-glucohydrolase DEFINITION Oleuropein + H2O <=> Oleuropein aglycone + D-Glucose EQUATION C09794 + C00001 <=> C21786 + C00031 RCLASS RC00049 C00031_C09794 C09794_C21786 ENZYME 3.2.1.206 BRITE Enzymatic reactions [BR:br08201] 3. Hydrolase reactions 3.2 Glycosylases 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds 3.2.1.206 R11942 Oleuropein + H2O <=> Oleuropein aglycone + D-Glucose ORTHOLOGY K22425 oleuropein beta-glucosidase [EC:3.2.1.206] DBLINKS RHEA: 55743 /// ENTRY R11943 Reaction NAME CoB,CoM,ferredoxin:H2 oxidoreductase DEFINITION Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Hydrogen EQUATION C04628 + C03576 + 2 C00138 + 2 C00080 <=> C04832 + 2 C00139 + 2 C00282 RCLASS RC00011 C03576_C04832 C04628_C04832 ENZYME 1.8.98.5 PATHWAY rn00680 Methane metabolism rn01100 Metabolic pathways rn01120 Microbial metabolism in diverse environments rn01200 Carbon metabolism MODULE M00356 Methanogenesis, methanol => methane M00357 Methanogenesis, acetate => methane M00563 Methanogenesis, methylamine/dimethylamine/trimethylamine => methane M00567 Methanogenesis, CO2 => methane BRITE Enzymatic reactions [BR:br08201] 1. Oxidoreductase reactions 1.8 Acting on a sulfur group of donors 1.8.98 With other, known, physiological acceptors 1.8.98.5 R11943 Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Hydrogen ORTHOLOGY K03388 heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] K03389 heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] K03390 heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] K14126 F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5] K14127 F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6] K14128 F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5] DBLINKS RHEA: 55751 55755 /// ENTRY R00321 Reaction NAME acetamide amidohydrolase DEFINITION Acetamide + H2O <=> Acetate + Ammonia EQUATION C06244 + C00001 <=> C00033 + C00014 RCLASS RC01313 C00033_C06244 ENZYME 3.5.1.4 BRITE Enzymatic reactions [BR:br08201] 3. Hydrolase reactions 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds 3.5.1 In linear amides 3.5.1.4 R00321 Acetamide + H2O <=> Acetate + Ammonia IUBMB reaction hierarchy [BR:br08202] 3. Hydrolase reactions 3.5.1.4 R03909 Monocarboxylic acid amide <=> Carboxylate R00321 Acetamide <=> Acetate DBLINKS RHEA: 45051 /// ENTRY R09404 Reaction DEFINITION Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+ EQUATION C06800 + C00007 + C00005 + C00080 <=> C19585 + C00001 + C00006 COMMENT CYP3A4/5 RCLASS RC00001 C00005_C00006 RC00277 C06800_C19585 ENZYME 1.14.14.1 1.14.14.- PATHWAY rn00980 Metabolism of xenobiotics by cytochrome P450 BRITE Enzymatic reactions [BR:br08201] 1. Oxidoreductase reactions 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor 1.14.14.1 R09404 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+ 1.14.14.- R09404 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+ ORTHOLOGY K17689 cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-] K17690 cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1] /// ENTRY R04378 Reaction NAME 1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide:pyrophosphate phosphoribosyltransferase DEFINITION 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate EQUATION C04677 + C00013 <=> C04051 + C00119 RCLASS RC00063 C04051_C04677 ENZYME 2.4.2.7 PATHWAY rn00230 Purine metabolism rn01100 Metabolic pathways BRITE Enzymatic reactions [BR:br08201] 2. Transferase reactions 2.4 Glycosyltransferases 2.4.2 Pentosyltransferases 2.4.2.7 R04378 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate ORTHOLOGY K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] DBLINKS RHEA: 31138 ///