ENTRY 10458 CDS T01001 SYMBOL BAIAP2, BAP2, FLAF3, IRSP53, WAML NAME (RefSeq) BAR/IMD domain containing adaptor protein 2 ORTHOLOGY K05627 BAI1-associated protein 2 ORGANISM hsa Homo sapiens (human) PATHWAY hsa04520 Adherens junction hsa04810 Regulation of actin cytoskeleton hsa05130 Pathogenic Escherichia coli infection hsa05135 Yersinia infection NETWORK nt06180 Pathogenic Escherichia coli ELEMENT N01094 Escherichia Eae/Tir/TccP to Actin signaling pathway BRITE KEGG Orthology (KO) [BR:hsa00001] 09160 Human Diseases 09171 Infectious disease: bacterial 05130 Pathogenic Escherichia coli infection 10458 (BAIAP2) 05135 Yersinia infection 10458 (BAIAP2) 09180 Brite Hierarchies 09182 Protein families: genetic information processing 04131 Membrane trafficking [BR:hsa04131] 10458 (BAIAP2) Membrane trafficking [BR:hsa04131] Endocytosis Bin/Amphiphysin/Rvs (BAR) family proteins I-BAR proteins 10458 (BAIAP2) POSITION 17:81035151..81117434 MOTIF Pfam: IMD SH3_2 SH3_9 SH3_1 BAR NDC80_loop Peptidase_Mx1 BAR_3 DBLINKS NCBI-GeneID: 10458 NCBI-ProteinID: NP_059345 OMIM: 605475 HGNC: 947 Ensembl: ENSG00000175866 UniProt: Q9UQB8 STRUCTURE PDB AASEQ 552 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRCDLSAQGPEGRE HGDGSARTLAGR NTSEQ 1659 atgtctctgtctcgctcagaggagatgcaccggctcacggaaaatgtctataagaccatc atggagcagttcaaccctagcctccggaacttcatcgccatggggaagaattacgagaag gcactggcaggtgtgacgtatgcagccaaaggctactttgacgccctggtgaagatgggg gagctggccagcgagagccagggctccaaagaactcggagacgttctcttccagatggct gaagtccacaggcagatccagaatcagctggaagaaatgctgaagtcttttcacaacgag ctgcttacgcagctggagcagaaggtggagctggactccaggtatctgagtgctgcgctg aagaaataccagactgagcaaaggagcaaaggcgacgccctggacaagtgtcaggctgag ctgaagaagcttcggaagaagagccagggcagcaagaatcctcagaagtactcggacaag gagctgcagtacatcgacgccatcagcaacaagcagggcgagctggagaattacgtgtcc gacggctacaagaccgcactgacagaggagcgcaggcgcttctgcttcctggtggagaag cagtgcgccgtggccaagaactccgcggcctaccactccaagggcaaggagctgctggcg cagaagctgccgctgtggcaacaggcctgtgccgaccccagcaagatcccggagcgcgcg gtgcagctcatgcagcaggtggccagcaacggcgccaccctccccagcgccctgtcggcc tccaagtccaacctggtcatttccgaccccattccgggggccaagcccctgccggtgccc cccgagctggcaccgttcgtggggcggatgtctgcccaggagagcacacccatcatgaac ggcgtcacaggcccggatggcgaggactacagcccgtgggctgaccgcaaggctgcccag cccaaatccctgtctcctccgcagtctcagagcaagctcagcgactcctactccaacaca ctccccgtgcgcaagagcgtgaccccaaaaaacagctatgccaccaccgagaacaagact ctgcctcgctcgagctccatggcagccggcctggagcgcaatggccgtatgcgggtgaag gccatcttctcccacgctgctggggacaacagcaccctcctgagcttcaaggagggtgac ctcattaccctgctggtgcctgaggcccgcgatggctggcactacggagagagtgagaag accaagatgcggggctggtttcccttctcctacacccgggtcttggacagcgatggcagt gacaggctgcacatgagcctgcagcaagggaagagcagcagcacgggcaacctcctggac aaggacgacctggccatcccaccccccgattacggcgccgcctcccgggccttccccgcc cagacggccagcggcttcaagcagaggccctacagtgtggccgtgcccgccttctcccag ggcctggatgactatggagcgcggtccatgagcaggaatccctttgcccacgtccagctg aagccgacagtgaccaacgacaggtgtgatctgtccgcccaagggccagaaggccgggag cacggggatgggagcgcccgcaccctggctggaagatga /// ENTRY Z5100 CDS T00044 SYMBOL espF NAME (GenBank) espF ORTHOLOGY K12786 LEE-encoded effector EspF ORGANISM ece Escherichia coli O157:H7 EDL933 (EHEC) PATHWAY ece05130 Pathogenic Escherichia coli infection MODULE ece_M00542 EHEC/EPEC pathogenicity signature, T3SS and effectors BRITE KEGG Orthology (KO) [BR:ece00001] 09160 Human Diseases 09171 Infectious disease: bacterial 05130 Pathogenic Escherichia coli infection Z5100 (espF) POSITION complement(4658240..4658986) MOTIF Pfam: EspF DBLINKS NCBI-ProteinID: AAG58814 UniProt: A0A9Q7EE73 AASEQ 248 MLNGISNAASTLGRQLVGIASRVSSAGGTGFSVAPQAVRLTPVKVHSPFSPGSSNVNART IFNVSSQVTSFTPSRPAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKP ARQAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTSGQA SGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTGPSGLPPLAQALKDHLA AYEQSKKG NTSEQ 747 atgcttaatggaattagtaacgctgcttctacactagggcggcagcttgtaggtatcgca agtcgagtgagctctgcggggggaactggattttctgtagcccctcaggccgtgcgtctt actccggtgaaagttcattcccctttttctccaggctcgtcgaatgttaatgcgagaacg atttttaatgtgagcagccaggtgacttcatttactccctctcgtccggcaccgccgcca ccgacaagtggacaggcatccggggcatcccgacctttaccgcccattgcacaggcatta aaagagcacttggctgcctatgaaaaatcgaaaggtcctgaggctttaggttttaagccc gcccgtcaggcaccgccgccaccgacaagtggacaggcatccggggcatcccgaccttta ccgcccattgcacaggcattaaaagagcacttggctgcctatgaaaaatcgaaaggtcct gaggctttaggttttaagcccgcccgtcaggcaccgccgccaccgacaagtggacaggca tccggggcatcccgacctttaccgcccattgcacaggcattaaaagagcacttggctgcc tatgaaaaatcgaaaggtcctgaggctttaggttttaagcccgcccgtcaggcaccaccg ccaccgacagggcctagtggactaccgccccttgcacaggcattaaaagatcatttagct gcctatgagcaatcgaagaaagggtaa ///