ENTRY       EC 1.5.3.15                 Enzyme
NAME        N8-acetylspermidine oxidase (propane-1,3-diamine-forming)
CLASS       Oxidoreductases;
            Acting on the CH-NH group of donors;
            With oxygen as acceptor
SYSNAME     N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming)
REACTION    N8-acetylspermidine + O2 + H2O = propane-1,3-diamine + 4-acetamidobutanal + H2O2 [RN:R09075]
ALL_REAC    R09075
SUBSTRATE   N8-acetylspermidine [CPD:C01029];
            O2 [CPD:C00007];
            H2O [CPD:C00001]
PRODUCT     propane-1,3-diamine [CPD:C00986];
            4-acetamidobutanal [CPD:C05936];
            H2O2 [CPD:C00027]
COMMENT     Also active with N1-acetylspermine, weak activity with N1,N12-diacetylspermine. No activity with diaminopropane, putrescine, cadaverine, diaminohexane, norspermidine, spermine and spermidine. Absence of monoamine oxidase (EC 1.4.3.4) activity. Differs in specificity from EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase).
HISTORY     EC 1.5.3.15 created 2009
REFERENCE   1  [PMID:1565141]
  AUTHORS   Shukla OP, Muller S, Walter RD
  TITLE     Polyamine oxidase from Acanthamoeba culbertsoni specific for N8-acetylspermidine.
  JOURNAL   Mol Biochem Parasitol 51:91-8 (1992)
            DOI:10.1016/0166-6851(92)90204-W
DBLINKS     ExplorEnz - The Enzyme Database: 1.5.3.15
            IUBMB Enzyme Nomenclature: 1.5.3.15
            ExPASy - ENZYME nomenclature database: 1.5.3.15
            BRENDA, the Enzyme Database: 1.5.3.15
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