{
	"name":"br08901",
	"children":[
	{
		"name":"Metabolism",
		"children":[
		{
			"name":"Global and overview maps",
			"children":[
			{
				"name":"01100  Metabolic pathways"
			},
			{
				"name":"01110  Biosynthesis of secondary metabolites"
			},
			{
				"name":"01120  Microbial metabolism in diverse environments"
			},
			{
				"name":"01200  Carbon metabolism"
			},
			{
				"name":"01210  2-Oxocarboxylic acid metabolism"
			},
			{
				"name":"01212  Fatty acid metabolism"
			},
			{
				"name":"01230  Biosynthesis of amino acids"
			},
			{
				"name":"01232  Nucleotide metabolism"
			},
			{
				"name":"01250  Biosynthesis of nucleotide sugars"
			},
			{
				"name":"01240  Biosynthesis of cofactors"
			},
			{
				"name":"01220  Degradation of aromatic compounds"
			},
			{
				"name":"01310  Nitrogen cycle"
			},
			{
				"name":"01320  Sulfur cycle"
			}
			]
		},
		{
			"name":"Carbohydrate metabolism",
			"children":[
			{
				"name":"00010  Glycolysis \/ Gluconeogenesis"
			},
			{
				"name":"00020  Citrate cycle (TCA cycle)"
			},
			{
				"name":"00030  Pentose phosphate pathway"
			},
			{
				"name":"00040  Pentose and glucuronate interconversions"
			},
			{
				"name":"00051  Fructose and mannose metabolism"
			},
			{
				"name":"00052  Galactose metabolism"
			},
			{
				"name":"00053  Ascorbate and aldarate metabolism"
			},
			{
				"name":"00500  Starch and sucrose metabolism"
			},
			{
				"name":"00620  Pyruvate metabolism"
			},
			{
				"name":"00630  Glyoxylate and dicarboxylate metabolism"
			},
			{
				"name":"00640  Propanoate metabolism"
			},
			{
				"name":"00650  Butanoate metabolism"
			},
			{
				"name":"00660  C5-Branched dibasic acid metabolism"
			},
			{
				"name":"00562  Inositol phosphate metabolism"
			},
			{
				"name":"00566  Sulfoquinovose metabolism"
			}
			]
		},
		{
			"name":"Energy metabolism",
			"children":[
			{
				"name":"00190  Oxidative phosphorylation"
			},
			{
				"name":"00195  Photosynthesis"
			},
			{
				"name":"00196  Photosynthesis - antenna proteins"
			},
			{
				"name":"00710  Carbon fixation by Calvin cycle"
			},
			{
				"name":"00720  Other carbon fixation pathways"
			},
			{
				"name":"00680  Methane metabolism"
			},
			{
				"name":"00910  Nitrogen metabolism"
			},
			{
				"name":"00920  Sulfur metabolism"
			}
			]
		},
		{
			"name":"Lipid metabolism",
			"children":[
			{
				"name":"00061  Fatty acid biosynthesis"
			},
			{
				"name":"00062  Fatty acid elongation"
			},
			{
				"name":"00071  Fatty acid degradation"
			},
			{
				"name":"00073  Cutin, suberine and wax biosynthesis"
			},
			{
				"name":"00074  Mycolic acid biosynthesis"
			},
			{
				"name":"00100  Steroid biosynthesis"
			},
			{
				"name":"00120  Primary bile acid biosynthesis"
			},
			{
				"name":"00121  Secondary bile acid biosynthesis"
			},
			{
				"name":"00140  Steroid hormone biosynthesis"
			},
			{
				"name":"00561  Glycerolipid metabolism"
			},
			{
				"name":"00564  Glycerophospholipid metabolism"
			},
			{
				"name":"00565  Ether lipid metabolism"
			},
			{
				"name":"00600  Sphingolipid metabolism"
			},
			{
				"name":"00590  Arachidonic acid metabolism"
			},
			{
				"name":"00591  Linoleic acid metabolism"
			},
			{
				"name":"00592  alpha-Linolenic acid metabolism"
			},
			{
				"name":"01040  Biosynthesis of unsaturated fatty acids"
			}
			]
		},
		{
			"name":"Nucleotide metabolism",
			"children":[
			{
				"name":"00230  Purine metabolism"
			},
			{
				"name":"00240  Pyrimidine metabolism"
			}
			]
		},
		{
			"name":"Amino acid metabolism",
			"children":[
			{
				"name":"00250  Alanine, aspartate and glutamate metabolism"
			},
			{
				"name":"00260  Glycine, serine and threonine metabolism"
			},
			{
				"name":"00270  Cysteine and methionine metabolism"
			},
			{
				"name":"00280  Valine, leucine and isoleucine degradation"
			},
			{
				"name":"00290  Valine, leucine and isoleucine biosynthesis"
			},
			{
				"name":"00300  Lysine biosynthesis"
			},
			{
				"name":"00310  Lysine degradation"
			},
			{
				"name":"00220  Arginine biosynthesis"
			},
			{
				"name":"00330  Arginine and proline metabolism"
			},
			{
				"name":"00340  Histidine metabolism"
			},
			{
				"name":"00350  Tyrosine metabolism"
			},
			{
				"name":"00360  Phenylalanine metabolism"
			},
			{
				"name":"00380  Tryptophan metabolism"
			},
			{
				"name":"00400  Phenylalanine, tyrosine and tryptophan biosynthesis"
			}
			]
		},
		{
			"name":"Metabolism of other amino acids",
			"children":[
			{
				"name":"00410  beta-Alanine metabolism"
			},
			{
				"name":"00430  Taurine and hypotaurine metabolism"
			},
			{
				"name":"00440  Phosphonate and phosphinate metabolism"
			},
			{
				"name":"00450  Selenocompound metabolism"
			},
			{
				"name":"00460  Cyanoamino acid metabolism"
			},
			{
				"name":"00470  D-Amino acid metabolism"
			},
			{
				"name":"00480  Glutathione metabolism"
			}
			]
		},
		{
			"name":"Glycan biosynthesis and metabolism",
			"children":[
			{
				"name":"00520  Amino sugar and nucleotide sugar metabolism"
			},
			{
				"name":"00541  Biosynthesis of various nucleotide sugars"
			},
			{
				"name":"00510  N-Glycan biosynthesis"
			},
			{
				"name":"00513  Various types of N-glycan biosynthesis"
			},
			{
				"name":"00512  Mucin type O-glycan biosynthesis"
			},
			{
				"name":"00515  Mannose type O-glycan biosynthesis"
			},
			{
				"name":"00514  Other types of O-glycan biosynthesis"
			},
			{
				"name":"00532  Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate"
			},
			{
				"name":"00534  Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin"
			},
			{
				"name":"00533  Glycosaminoglycan biosynthesis - keratan sulfate"
			},
			{
				"name":"00531  Glycosaminoglycan degradation"
			},
			{
				"name":"00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
			},
			{
				"name":"00601  Glycosphingolipid biosynthesis - lacto and neolacto series"
			},
			{
				"name":"00603  Glycosphingolipid biosynthesis - globo and isoglobo series"
			},
			{
				"name":"00604  Glycosphingolipid biosynthesis - ganglio series"
			},
			{
				"name":"00511  Other glycan degradation"
			},
			{
				"name":"00540  Lipopolysaccharide biosynthesis"
			},
			{
				"name":"00542  O-Antigen repeat unit biosynthesis"
			},
			{
				"name":"00550  Peptidoglycan biosynthesis"
			},
			{
				"name":"00552  Teichoic acid biosynthesis"
			},
			{
				"name":"00571  Lipoarabinomannan (LAM) biosynthesis"
			},
			{
				"name":"00572  Arabinogalactan biosynthesis - Mycobacterium"
			},
			{
				"name":"00543  Exopolysaccharide biosynthesis"
			}
			]
		},
		{
			"name":"Metabolism of cofactors and vitamins",
			"children":[
			{
				"name":"00730  Thiamine metabolism"
			},
			{
				"name":"00740  Riboflavin metabolism"
			},
			{
				"name":"00750  Vitamin B6 metabolism"
			},
			{
				"name":"00760  Nicotinate and nicotinamide metabolism"
			},
			{
				"name":"00770  Pantothenate and CoA biosynthesis"
			},
			{
				"name":"00780  Biotin metabolism"
			},
			{
				"name":"00785  Lipoic acid metabolism"
			},
			{
				"name":"00790  Folate biosynthesis"
			},
			{
				"name":"00670  One carbon pool by folate"
			},
			{
				"name":"00830  Retinol metabolism"
			},
			{
				"name":"00860  Porphyrin metabolism"
			},
			{
				"name":"00130  Ubiquinone and other terpenoid-quinone biosynthesis"
			}
			]
		},
		{
			"name":"Metabolism of terpenoids and polyketides",
			"children":[
			{
				"name":"00900  Terpenoid backbone biosynthesis"
			},
			{
				"name":"00902  Monoterpenoid biosynthesis"
			},
			{
				"name":"00909  Sesquiterpenoid and triterpenoid biosynthesis"
			},
			{
				"name":"00904  Diterpenoid biosynthesis"
			},
			{
				"name":"00906  Carotenoid biosynthesis"
			},
			{
				"name":"00905  Brassinosteroid biosynthesis"
			},
			{
				"name":"00981  Insect hormone biosynthesis"
			},
			{
				"name":"00908  Zeatin biosynthesis"
			},
			{
				"name":"00903  Limonene degradation"
			},
			{
				"name":"00907  Pinene, camphor and geraniol degradation"
			},
			{
				"name":"01052  Type I polyketide structures"
			},
			{
				"name":"00522  Biosynthesis of 12-, 14- and 16-membered macrolides"
			},
			{
				"name":"01051  Biosynthesis of ansamycins"
			},
			{
				"name":"01059  Biosynthesis of enediyne antibiotics"
			},
			{
				"name":"01056  Biosynthesis of type II polyketide backbone"
			},
			{
				"name":"01057  Biosynthesis of type II polyketide products"
			},
			{
				"name":"00253  Tetracycline biosynthesis"
			},
			{
				"name":"00523  Polyketide sugar unit biosynthesis"
			},
			{
				"name":"01054  Nonribosomal peptide structures"
			},
			{
				"name":"01053  Biosynthesis of siderophore group nonribosomal peptides"
			},
			{
				"name":"01055  Biosynthesis of vancomycin group antibiotics"
			}
			]
		},
		{
			"name":"Biosynthesis of other secondary metabolites",
			"children":[
			{
				"name":"00940  Phenylpropanoid biosynthesis"
			},
			{
				"name":"00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis"
			},
			{
				"name":"00941  Flavonoid biosynthesis"
			},
			{
				"name":"00944  Flavone and flavonol biosynthesis"
			},
			{
				"name":"00942  Anthocyanin biosynthesis"
			},
			{
				"name":"00943  Isoflavonoid biosynthesis"
			},
			{
				"name":"00946  Degradation of flavonoids"
			},
			{
				"name":"00901  Indole alkaloid biosynthesis"
			},
			{
				"name":"00403  Indole diterpene alkaloid biosynthesis"
			},
			{
				"name":"00950  Isoquinoline alkaloid biosynthesis"
			},
			{
				"name":"00960  Tropane, piperidine and pyridine alkaloid biosynthesis"
			},
			{
				"name":"00996  Biosynthesis of various alkaloids"
			},
			{
				"name":"00232  Caffeine metabolism"
			},
			{
				"name":"00965  Betalain biosynthesis"
			},
			{
				"name":"00966  Glucosinolate biosynthesis"
			},
			{
				"name":"00402  Benzoxazinoid biosynthesis"
			},
			{
				"name":"00311  Penicillin and cephalosporin biosynthesis"
			},
			{
				"name":"00332  Carbapenem biosynthesis"
			},
			{
				"name":"00261  Monobactam biosynthesis"
			},
			{
				"name":"00331  Clavulanic acid biosynthesis"
			},
			{
				"name":"00521  Streptomycin biosynthesis"
			},
			{
				"name":"00524  Neomycin, kanamycin and gentamicin biosynthesis"
			},
			{
				"name":"00525  Acarbose and validamycin biosynthesis"
			},
			{
				"name":"00401  Novobiocin biosynthesis"
			},
			{
				"name":"00404  Staurosporine biosynthesis"
			},
			{
				"name":"00405  Phenazine biosynthesis"
			},
			{
				"name":"00333  Prodigiosin biosynthesis"
			},
			{
				"name":"00254  Aflatoxin biosynthesis"
			},
			{
				"name":"00975  Biosynthesis of various siderophores"
			},
			{
				"name":"00998  Biosynthesis of various antibiotics"
			},
			{
				"name":"00999  Biosynthesis of various plant secondary metabolites"
			},
			{
				"name":"00997  Biosynthesis of various other secondary metabolites"
			}
			]
		},
		{
			"name":"Xenobiotics biodegradation and metabolism",
			"children":[
			{
				"name":"00362  Benzoate degradation"
			},
			{
				"name":"00627  Aminobenzoate degradation"
			},
			{
				"name":"00364  Fluorobenzoate degradation"
			},
			{
				"name":"00625  Chloroalkane and chloroalkene degradation"
			},
			{
				"name":"00361  Chlorocyclohexane and chlorobenzene degradation"
			},
			{
				"name":"00623  Toluene degradation"
			},
			{
				"name":"00622  Xylene degradation"
			},
			{
				"name":"00633  Nitrotoluene degradation"
			},
			{
				"name":"00642  Ethylbenzene degradation"
			},
			{
				"name":"00643  Styrene degradation"
			},
			{
				"name":"00791  Atrazine degradation"
			},
			{
				"name":"00930  Caprolactam degradation"
			},
			{
				"name":"00363  Bisphenol degradation"
			},
			{
				"name":"00621  Dioxin degradation"
			},
			{
				"name":"00626  Naphthalene degradation"
			},
			{
				"name":"00624  Polycyclic aromatic hydrocarbon degradation"
			},
			{
				"name":"00365  Furfural degradation"
			},
			{
				"name":"00984  Steroid degradation"
			},
			{
				"name":"00980  Metabolism of xenobiotics by cytochrome P450"
			},
			{
				"name":"00982  Drug metabolism - cytochrome P450"
			},
			{
				"name":"00983  Drug metabolism - other enzymes"
			}
			]
		},
		{
			"name":"Chemical structure transformation maps",
			"children":[
			{
				"name":"01010  Overview of biosynthetic pathways"
			},
			{
				"name":"01060  Biosynthesis of plant secondary metabolites"
			},
			{
				"name":"01061  Biosynthesis of phenylpropanoids"
			},
			{
				"name":"01062  Biosynthesis of terpenoids and steroids"
			},
			{
				"name":"01063  Biosynthesis of alkaloids derived from shikimate pathway"
			},
			{
				"name":"01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid"
			},
			{
				"name":"01065  Biosynthesis of alkaloids derived from histidine and purine"
			},
			{
				"name":"01066  Biosynthesis of alkaloids derived from terpenoid and polyketide"
			},
			{
				"name":"01070  Biosynthesis of plant hormones"
			}
			]
		}
		]
	},
	{
		"name":"Genetic Information Processing",
		"children":[
		{
			"name":"Transcription",
			"children":[
			{
				"name":"03020  RNA polymerase"
			},
			{
				"name":"03022  Basal transcription factors"
			},
			{
				"name":"03040  Spliceosome"
			}
			]
		},
		{
			"name":"Translation",
			"children":[
			{
				"name":"03010  Ribosome"
			},
			{
				"name":"00970  Aminoacyl-tRNA biosynthesis"
			},
			{
				"name":"03013  Nucleocytoplasmic transport"
			},
			{
				"name":"03015  mRNA surveillance pathway"
			},
			{
				"name":"03008  Ribosome biogenesis in eukaryotes"
			}
			]
		},
		{
			"name":"Folding, sorting and degradation",
			"children":[
			{
				"name":"03060  Protein export"
			},
			{
				"name":"04141  Protein processing in endoplasmic reticulum"
			},
			{
				"name":"04130  SNARE interactions in vesicular transport"
			},
			{
				"name":"04120  Ubiquitin mediated proteolysis"
			},
			{
				"name":"04122  Sulfur relay system"
			},
			{
				"name":"03050  Proteasome"
			},
			{
				"name":"03018  RNA degradation"
			}
			]
		},
		{
			"name":"Replication and repair",
			"children":[
			{
				"name":"03030  DNA replication"
			},
			{
				"name":"03410  Base excision repair"
			},
			{
				"name":"03420  Nucleotide excision repair"
			},
			{
				"name":"03430  Mismatch repair"
			},
			{
				"name":"03440  Homologous recombination"
			},
			{
				"name":"03450  Non-homologous end-joining"
			},
			{
				"name":"03460  Fanconi anemia pathway"
			}
			]
		},
		{
			"name":"Chromosome",
			"children":[
			{
				"name":"03082  ATP-dependent chromatin remodeling"
			},
			{
				"name":"03083  Polycomb repressive complex"
			}
			]
		},
		{
			"name":"Information processing in viruses",
			"children":[
			{
				"name":"03230  Viral genome structure"
			},
			{
				"name":"03240  Viral replication"
			},
			{
				"name":"03250  Viral life cycle - HIV-1"
			},
			{
				"name":"03260  Virion - Human immunodeficiency virus"
			},
			{
				"name":"03271  Virion - Rotavirus"
			},
			{
				"name":"03262  Virion - Coronavirus"
			},
			{
				"name":"03261  Virion - Influenza virus"
			},
			{
				"name":"03263  Virion - Enterovirus"
			},
			{
				"name":"03264  Virion - Flavivirus and Alphavirus"
			},
			{
				"name":"03265  Virion - Ebolavirus, Lyssavirus and Morbillivirus"
			},
			{
				"name":"03273  Virion - Lassa virus and SFTS virus"
			},
			{
				"name":"03272  Virion - Hepatitis viruses"
			},
			{
				"name":"03266  Virion - Herpesvirus"
			},
			{
				"name":"03268  Virion - Orthopoxvirus"
			},
			{
				"name":"03267  Virion - Adenovirus"
			},
			{
				"name":"03259  Virion - Bacteriophages T4 and T7"
			},
			{
				"name":"03258  Virion - Bacteriophage lambda"
			}
			]
		}
		]
	},
	{
		"name":"Environmental Information Processing",
		"children":[
		{
			"name":"Membrane transport",
			"children":[
			{
				"name":"02010  ABC transporters"
			},
			{
				"name":"02060  Phosphotransferase system (PTS)"
			},
			{
				"name":"03070  Bacterial secretion system"
			}
			]
		},
		{
			"name":"Signal transduction",
			"children":[
			{
				"name":"02020  Two-component system"
			},
			{
				"name":"04010  MAPK signaling pathway"
			},
			{
				"name":"04013  MAPK signaling pathway - fly"
			},
			{
				"name":"04016  MAPK signaling pathway - plant"
			},
			{
				"name":"04011  MAPK signaling pathway - yeast"
			},
			{
				"name":"04012  ErbB signaling pathway"
			},
			{
				"name":"04014  Ras signaling pathway"
			},
			{
				"name":"04015  Rap1 signaling pathway"
			},
			{
				"name":"04310  Wnt signaling pathway"
			},
			{
				"name":"04330  Notch signaling pathway"
			},
			{
				"name":"04340  Hedgehog signaling pathway"
			},
			{
				"name":"04341  Hedgehog signaling pathway - fly"
			},
			{
				"name":"04350  TGF-beta signaling pathway"
			},
			{
				"name":"04390  Hippo signaling pathway"
			},
			{
				"name":"04391  Hippo signaling pathway - fly"
			},
			{
				"name":"04392  Hippo signaling pathway - multiple species"
			},
			{
				"name":"04370  VEGF signaling pathway"
			},
			{
				"name":"04371  Apelin signaling pathway"
			},
			{
				"name":"04630  JAK-STAT signaling pathway"
			},
			{
				"name":"04064  NF-kappa B signaling pathway"
			},
			{
				"name":"04668  TNF signaling pathway"
			},
			{
				"name":"04066  HIF-1 signaling pathway"
			},
			{
				"name":"04068  FoxO signaling pathway"
			},
			{
				"name":"04020  Calcium signaling pathway"
			},
			{
				"name":"04070  Phosphatidylinositol signaling system"
			},
			{
				"name":"04072  Phospholipase D signaling pathway"
			},
			{
				"name":"04071  Sphingolipid signaling pathway"
			},
			{
				"name":"04024  cAMP signaling pathway"
			},
			{
				"name":"04022  cGMP-PKG signaling pathway"
			},
			{
				"name":"04151  PI3K-Akt signaling pathway"
			},
			{
				"name":"04152  AMPK signaling pathway"
			},
			{
				"name":"04150  mTOR signaling pathway"
			},
			{
				"name":"04075  Plant hormone signal transduction"
			}
			]
		},
		{
			"name":"Signaling molecules and interaction",
			"children":[
			{
				"name":"04080  Neuroactive ligand-receptor interaction"
			},
			{
				"name":"04082  Neuroactive ligand signaling"
			},
			{
				"name":"04081  Hormone signaling"
			},
			{
				"name":"04060  Cytokine-cytokine receptor interaction"
			},
			{
				"name":"04061  Viral protein interaction with cytokine and cytokine receptor"
			},
			{
				"name":"04512  ECM-receptor interaction"
			},
			{
				"name":"04514  Cell adhesion molecule (CAM) interaction"
			},
			{
				"name":"04517  IgSF CAM signaling"
			},
			{
				"name":"04518  Integrin signaling"
			},
			{
				"name":"04519  Cadherin signaling"
			}
			]
		}
		]
	},
	{
		"name":"Cellular Processes",
		"children":[
		{
			"name":"Transport and catabolism",
			"children":[
			{
				"name":"04144  Endocytosis"
			},
			{
				"name":"04145  Phagosome"
			},
			{
				"name":"04142  Lysosome biogenesis"
			},
			{
				"name":"04146  Peroxisome"
			},
			{
				"name":"04140  Autophagy - animal"
			},
			{
				"name":"04138  Autophagy - yeast"
			},
			{
				"name":"04136  Autophagy - other"
			},
			{
				"name":"04137  Mitophagy - animal"
			},
			{
				"name":"04139  Mitophagy - yeast"
			},
			{
				"name":"04148  Efferocytosis"
			}
			]
		},
		{
			"name":"Cell growth and death",
			"children":[
			{
				"name":"04110  Cell cycle"
			},
			{
				"name":"04111  Cell cycle - yeast"
			},
			{
				"name":"04112  Cell cycle - Caulobacter"
			},
			{
				"name":"04113  Meiosis - yeast"
			},
			{
				"name":"04114  Oocyte meiosis"
			},
			{
				"name":"04210  Apoptosis"
			},
			{
				"name":"04214  Apoptosis - fly"
			},
			{
				"name":"04215  Apoptosis - multiple species"
			},
			{
				"name":"04216  Ferroptosis"
			},
			{
				"name":"04217  Necroptosis"
			},
			{
				"name":"04115  p53 signaling pathway"
			},
			{
				"name":"04218  Cellular senescence"
			}
			]
		},
		{
			"name":"Cellular community - eukaryotes",
			"children":[
			{
				"name":"04510  Focal adhesion"
			},
			{
				"name":"04520  Adherens junction"
			},
			{
				"name":"04530  Tight junction"
			},
			{
				"name":"04540  Gap junction"
			},
			{
				"name":"04550  Signaling pathways regulating pluripotency of stem cells"
			}
			]
		},
		{
			"name":"Cellular community - prokaryotes",
			"children":[
			{
				"name":"02024  Quorum sensing"
			},
			{
				"name":"05111  Biofilm formation - Vibrio cholerae"
			},
			{
				"name":"02025  Biofilm formation - Pseudomonas aeruginosa"
			},
			{
				"name":"02026  Biofilm formation - Escherichia coli"
			}
			]
		},
		{
			"name":"Cell motility",
			"children":[
			{
				"name":"02030  Bacterial chemotaxis"
			},
			{
				"name":"02040  Flagellar assembly"
			},
			{
				"name":"04814  Motor proteins"
			},
			{
				"name":"04820  Cytoskeleton in muscle cells"
			},
			{
				"name":"04810  Regulation of actin cytoskeleton"
			}
			]
		}
		]
	},
	{
		"name":"Organismal Systems",
		"children":[
		{
			"name":"Immune system",
			"children":[
			{
				"name":"04640  Hematopoietic cell lineage"
			},
			{
				"name":"04610  Complement and coagulation cascades"
			},
			{
				"name":"04611  Platelet activation"
			},
			{
				"name":"04613  Neutrophil extracellular trap formation"
			},
			{
				"name":"04620  Toll-like receptor signaling pathway"
			},
			{
				"name":"04624  Toll and Imd signaling pathway"
			},
			{
				"name":"04621  NOD-like receptor signaling pathway"
			},
			{
				"name":"04622  RIG-I-like receptor signaling pathway"
			},
			{
				"name":"04623  Cytosolic DNA-sensing pathway"
			},
			{
				"name":"04625  C-type lectin receptor signaling pathway"
			},
			{
				"name":"04650  Natural killer cell mediated cytotoxicity"
			},
			{
				"name":"04612  Antigen processing and presentation"
			},
			{
				"name":"04660  T cell receptor signaling pathway"
			},
			{
				"name":"04658  Th1 and Th2 cell differentiation"
			},
			{
				"name":"04659  Th17 cell differentiation"
			},
			{
				"name":"04657  IL-17 signaling pathway"
			},
			{
				"name":"04662  B cell receptor signaling pathway"
			},
			{
				"name":"04664  Fc epsilon RI signaling pathway"
			},
			{
				"name":"04666  Fc gamma R-mediated phagocytosis"
			},
			{
				"name":"04670  Leukocyte transendothelial migration"
			},
			{
				"name":"04672  Intestinal immune network for IgA production"
			},
			{
				"name":"04062  Chemokine signaling pathway"
			}
			]
		},
		{
			"name":"Endocrine system",
			"children":[
			{
				"name":"04911  Insulin secretion"
			},
			{
				"name":"04910  Insulin signaling pathway"
			},
			{
				"name":"04922  Glucagon signaling pathway"
			},
			{
				"name":"04923  Regulation of lipolysis in adipocytes"
			},
			{
				"name":"04920  Adipocytokine signaling pathway"
			},
			{
				"name":"03320  PPAR signaling pathway"
			},
			{
				"name":"04929  GnRH secretion"
			},
			{
				"name":"04912  GnRH signaling pathway"
			},
			{
				"name":"04913  Ovarian steroidogenesis"
			},
			{
				"name":"04915  Estrogen signaling pathway"
			},
			{
				"name":"04914  Progesterone-mediated oocyte maturation"
			},
			{
				"name":"04917  Prolactin signaling pathway"
			},
			{
				"name":"04921  Oxytocin signaling pathway"
			},
			{
				"name":"04926  Relaxin signaling pathway"
			},
			{
				"name":"04935  Growth hormone synthesis, secretion and action"
			},
			{
				"name":"04918  Thyroid hormone synthesis"
			},
			{
				"name":"04919  Thyroid hormone signaling pathway"
			},
			{
				"name":"04928  Parathyroid hormone synthesis, secretion and action"
			},
			{
				"name":"04916  Melanogenesis"
			},
			{
				"name":"04924  Renin secretion"
			},
			{
				"name":"04614  Renin-angiotensin system"
			},
			{
				"name":"04925  Aldosterone synthesis and secretion"
			},
			{
				"name":"04927  Cortisol synthesis and secretion"
			}
			]
		},
		{
			"name":"Circulatory system",
			"children":[
			{
				"name":"04260  Cardiac muscle contraction"
			},
			{
				"name":"04261  Adrenergic signaling in cardiomyocytes"
			},
			{
				"name":"04270  Vascular smooth muscle contraction"
			}
			]
		},
		{
			"name":"Digestive system",
			"children":[
			{
				"name":"04970  Salivary secretion"
			},
			{
				"name":"04971  Gastric acid secretion"
			},
			{
				"name":"04972  Pancreatic secretion"
			},
			{
				"name":"04976  Bile secretion"
			},
			{
				"name":"04973  Carbohydrate digestion and absorption"
			},
			{
				"name":"04974  Protein digestion and absorption"
			},
			{
				"name":"04975  Fat digestion and absorption"
			},
			{
				"name":"04979  Cholesterol metabolism"
			},
			{
				"name":"04977  Vitamin digestion and absorption"
			},
			{
				"name":"04981  Folate transport and metabolism"
			},
			{
				"name":"04980  Cobalamin transport and metabolism"
			},
			{
				"name":"04978  Mineral absorption"
			}
			]
		},
		{
			"name":"Excretory system",
			"children":[
			{
				"name":"04962  Vasopressin-regulated water reabsorption"
			},
			{
				"name":"04960  Aldosterone-regulated sodium reabsorption"
			},
			{
				"name":"04961  Endocrine and other factor-regulated calcium reabsorption"
			},
			{
				"name":"04964  Proximal tubule bicarbonate reclamation"
			},
			{
				"name":"04966  Collecting duct acid secretion"
			}
			]
		},
		{
			"name":"Nervous system",
			"children":[
			{
				"name":"04724  Glutamatergic synapse"
			},
			{
				"name":"04727  GABAergic synapse"
			},
			{
				"name":"04725  Cholinergic synapse"
			},
			{
				"name":"04728  Dopaminergic synapse"
			},
			{
				"name":"04726  Serotonergic synapse"
			},
			{
				"name":"04720  Long-term potentiation"
			},
			{
				"name":"04730  Long-term depression"
			},
			{
				"name":"04723  Retrograde endocannabinoid signaling"
			},
			{
				"name":"04721  Synaptic vesicle cycle"
			},
			{
				"name":"04722  Neurotrophin signaling pathway"
			}
			]
		},
		{
			"name":"Sensory system",
			"children":[
			{
				"name":"04744  Phototransduction"
			},
			{
				"name":"04745  Phototransduction - fly"
			},
			{
				"name":"04740  Olfactory transduction"
			},
			{
				"name":"04742  Taste transduction"
			},
			{
				"name":"04750  Inflammatory mediator regulation of TRP channels"
			}
			]
		},
		{
			"name":"Development and regeneration",
			"children":[
			{
				"name":"04320  Dorso-ventral axis formation"
			},
			{
				"name":"04360  Axon guidance"
			},
			{
				"name":"04361  Axon regeneration"
			},
			{
				"name":"04380  Osteoclast differentiation"
			},
			{
				"name":"04382  Cornified envelope formation"
			}
			]
		},
		{
			"name":"Aging",
			"children":[
			{
				"name":"04211  Longevity regulating pathway"
			},
			{
				"name":"04212  Longevity regulating pathway - worm"
			},
			{
				"name":"04213  Longevity regulating pathway - multiple species"
			}
			]
		},
		{
			"name":"Environmental adaptation",
			"children":[
			{
				"name":"04710  Circadian rhythm"
			},
			{
				"name":"04713  Circadian entrainment"
			},
			{
				"name":"04711  Circadian rhythm - fly"
			},
			{
				"name":"04712  Circadian rhythm - plant"
			},
			{
				"name":"04714  Thermogenesis"
			},
			{
				"name":"04626  Plant-pathogen interaction"
			}
			]
		}
		]
	},
	{
		"name":"Human Diseases",
		"children":[
		{
			"name":"Cancer: overview",
			"children":[
			{
				"name":"05200  Pathways in cancer"
			},
			{
				"name":"05202  Transcriptional misregulation in cancer"
			},
			{
				"name":"05206  MicroRNAs in cancer"
			},
			{
				"name":"05205  Proteoglycans in cancer"
			},
			{
				"name":"05204  Chemical carcinogenesis - DNA adducts"
			},
			{
				"name":"05207  Chemical carcinogenesis - receptor activation"
			},
			{
				"name":"05208  Chemical carcinogenesis - reactive oxygen species"
			},
			{
				"name":"05203  Viral carcinogenesis"
			},
			{
				"name":"05230  Central carbon metabolism in cancer"
			},
			{
				"name":"05231  Choline metabolism in cancer"
			},
			{
				"name":"05235  PD-L1 expression and PD-1 checkpoint pathway in cancer"
			}
			]
		},
		{
			"name":"Cancer: specific types",
			"children":[
			{
				"name":"05210  Colorectal cancer"
			},
			{
				"name":"05212  Pancreatic cancer"
			},
			{
				"name":"05225  Hepatocellular carcinoma"
			},
			{
				"name":"05226  Gastric cancer"
			},
			{
				"name":"05214  Glioma"
			},
			{
				"name":"05216  Thyroid cancer"
			},
			{
				"name":"05221  Acute myeloid leukemia"
			},
			{
				"name":"05220  Chronic myeloid leukemia"
			},
			{
				"name":"05217  Basal cell carcinoma"
			},
			{
				"name":"05218  Melanoma"
			},
			{
				"name":"05211  Renal cell carcinoma"
			},
			{
				"name":"05219  Bladder cancer"
			},
			{
				"name":"05215  Prostate cancer"
			},
			{
				"name":"05213  Endometrial cancer"
			},
			{
				"name":"05224  Breast cancer"
			},
			{
				"name":"05222  Small cell lung cancer"
			},
			{
				"name":"05223  Non-small cell lung cancer"
			}
			]
		},
		{
			"name":"Infectious disease: viral",
			"children":[
			{
				"name":"05166  Human T-cell leukemia virus 1 infection"
			},
			{
				"name":"05170  Human immunodeficiency virus 1 infection"
			},
			{
				"name":"05161  Hepatitis B"
			},
			{
				"name":"05160  Hepatitis C"
			},
			{
				"name":"05171  Coronavirus disease - COVID-19"
			},
			{
				"name":"05164  Influenza A"
			},
			{
				"name":"05162  Measles"
			},
			{
				"name":"05168  Herpes simplex virus 1 infection"
			},
			{
				"name":"05163  Human cytomegalovirus infection"
			},
			{
				"name":"05167  Kaposi sarcoma-associated herpesvirus infection"
			},
			{
				"name":"05169  Epstein-Barr virus infection"
			},
			{
				"name":"05165  Human papillomavirus infection"
			}
			]
		},
		{
			"name":"Infectious disease: bacterial",
			"children":[
			{
				"name":"05110  Vibrio cholerae infection"
			},
			{
				"name":"05120  Epithelial cell signaling in Helicobacter pylori infection"
			},
			{
				"name":"05130  Pathogenic Escherichia coli infection"
			},
			{
				"name":"05132  Salmonella infection"
			},
			{
				"name":"05131  Shigellosis"
			},
			{
				"name":"05135  Yersinia infection"
			},
			{
				"name":"05133  Pertussis"
			},
			{
				"name":"05134  Legionellosis"
			},
			{
				"name":"05150  Staphylococcus aureus infection"
			},
			{
				"name":"05152  Tuberculosis"
			},
			{
				"name":"05100  Bacterial invasion of epithelial cells"
			}
			]
		},
		{
			"name":"Infectious disease: parasitic",
			"children":[
			{
				"name":"05146  Amoebiasis"
			},
			{
				"name":"05144  Malaria"
			},
			{
				"name":"05145  Toxoplasmosis"
			},
			{
				"name":"05140  Leishmaniasis"
			},
			{
				"name":"05142  Chagas disease"
			},
			{
				"name":"05143  African trypanosomiasis"
			}
			]
		},
		{
			"name":"Immune disease",
			"children":[
			{
				"name":"05310  Asthma"
			},
			{
				"name":"05322  Systemic lupus erythematosus"
			},
			{
				"name":"05323  Rheumatoid arthritis"
			},
			{
				"name":"05320  Autoimmune thyroid disease"
			},
			{
				"name":"05321  Inflammatory bowel disease"
			},
			{
				"name":"05330  Allograft rejection"
			},
			{
				"name":"05332  Graft-versus-host disease"
			},
			{
				"name":"05340  Primary immunodeficiency"
			}
			]
		},
		{
			"name":"Neurodegenerative disease",
			"children":[
			{
				"name":"05010  Alzheimer disease"
			},
			{
				"name":"05012  Parkinson disease"
			},
			{
				"name":"05014  Amyotrophic lateral sclerosis"
			},
			{
				"name":"05016  Huntington disease"
			},
			{
				"name":"05017  Spinocerebellar ataxia"
			},
			{
				"name":"05020  Prion disease"
			},
			{
				"name":"05022  Pathways of neurodegeneration - multiple diseases"
			}
			]
		},
		{
			"name":"Substance dependence",
			"children":[
			{
				"name":"05030  Cocaine addiction"
			},
			{
				"name":"05031  Amphetamine addiction"
			},
			{
				"name":"05032  Morphine addiction"
			},
			{
				"name":"05033  Nicotine addiction"
			},
			{
				"name":"05034  Alcoholism"
			}
			]
		},
		{
			"name":"Cardiovascular disease",
			"children":[
			{
				"name":"05417  Lipid and atherosclerosis"
			},
			{
				"name":"05418  Fluid shear stress and atherosclerosis"
			},
			{
				"name":"05410  Hypertrophic cardiomyopathy"
			},
			{
				"name":"05412  Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"05414  Dilated cardiomyopathy"
			},
			{
				"name":"05415  Diabetic cardiomyopathy"
			},
			{
				"name":"05416  Viral myocarditis"
			}
			]
		},
		{
			"name":"Endocrine and metabolic disease",
			"children":[
			{
				"name":"04930  Type II diabetes mellitus"
			},
			{
				"name":"04940  Type I diabetes mellitus"
			},
			{
				"name":"04950  Maturity onset diabetes of the young"
			},
			{
				"name":"04936  Alcoholic liver disease"
			},
			{
				"name":"04932  Non-alcoholic fatty liver disease"
			},
			{
				"name":"04931  Insulin resistance"
			},
			{
				"name":"04933  AGE-RAGE signaling pathway in diabetic complications"
			},
			{
				"name":"04934  Cushing syndrome"
			}
			]
		},
		{
			"name":"Drug resistance: antimicrobial",
			"children":[
			{
				"name":"01501  beta-Lactam resistance"
			},
			{
				"name":"01502  Vancomycin resistance"
			},
			{
				"name":"01503  Cationic antimicrobial peptide (CAMP) resistance"
			}
			]
		},
		{
			"name":"Drug resistance: antineoplastic",
			"children":[
			{
				"name":"01521  EGFR tyrosine kinase inhibitor resistance"
			},
			{
				"name":"01524  Platinum drug resistance"
			},
			{
				"name":"01523  Antifolate resistance"
			},
			{
				"name":"01522  Endocrine resistance"
			}
			]
		}
		]
	},
	{
		"name":"Drug Development",
		"children":[
		{
			"name":"Chronology: Antiinfectives",
			"children":[
			{
				"name":"07011  Penicillins"
			},
			{
				"name":"07012  Cephalosporins - parenteral agents"
			},
			{
				"name":"07013  Cephalosporins - oral agents"
			},
			{
				"name":"07021  Aminoglycosides"
			},
			{
				"name":"07019  Tetracyclines"
			},
			{
				"name":"07020  Macrolides and ketolides"
			},
			{
				"name":"07014  Quinolones"
			},
			{
				"name":"07023  Rifamycins"
			},
			{
				"name":"07026  Antifungal agents"
			},
			{
				"name":"07044  Antiviral agents"
			},
			{
				"name":"07053  Anti-HIV agents"
			}
			]
		},
		{
			"name":"Chronology: Antineoplastics",
			"children":[
			{
				"name":"07040  Antineoplastics - alkylating agents"
			},
			{
				"name":"07041  Antineoplastics - antimetabolic agents"
			},
			{
				"name":"07042  Antineoplastics - agents from natural products"
			},
			{
				"name":"07043  Antineoplastics - hormones"
			},
			{
				"name":"07045  Antineoplastics - protein kinase inhibitors"
			}
			]
		},
		{
			"name":"Chronology: Nervous system agents",
			"children":[
			{
				"name":"07032  Hypnotics"
			},
			{
				"name":"07030  Anxiolytics"
			},
			{
				"name":"07033  Anticonvulsants"
			},
			{
				"name":"07015  Local analgesics"
			},
			{
				"name":"07039  Opioid analgesics"
			},
			{
				"name":"07028  Antipsychotics"
			},
			{
				"name":"07029  Antipsychotics - phenothiazines"
			},
			{
				"name":"07031  Antipsychotics - butyrophenones"
			},
			{
				"name":"07027  Antidepressants"
			},
			{
				"name":"07056  Agents for Alzheimer-type dementia"
			},
			{
				"name":"07057  Antiparkinsonian agents"
			}
			]
		},
		{
			"name":"Chronology: Other drugs",
			"children":[
			{
				"name":"07055  Sulfonamide derivatives - overview"
			},
			{
				"name":"07016  Sulfonamide derivatives - sulfa drugs"
			},
			{
				"name":"07017  Sulfonamide derivatives - diuretics"
			},
			{
				"name":"07018  Sulfonamide derivatives - hypoglycemic agents"
			},
			{
				"name":"07037  Antiarrhythmic drugs"
			},
			{
				"name":"07038  Antiulcer drugs"
			},
			{
				"name":"07046  Immunosuppressive agents"
			},
			{
				"name":"07047  Osteoporosis drugs"
			},
			{
				"name":"07048  Antimigraines"
			},
			{
				"name":"07049  Antithrombosis agents"
			},
			{
				"name":"07050  Antirheumatics - DMARDs and biological agents"
			},
			{
				"name":"07051  Antidiabetics"
			},
			{
				"name":"07052  Antidyslipidemic agents"
			},
			{
				"name":"07054  Antiglaucoma agents"
			}
			]
		},
		{
			"name":"Target-based classification: G protein-coupled receptors",
			"children":[
			{
				"name":"07220  Cholinergic and anticholinergic drugs"
			},
			{
				"name":"07215  alpha-Adrenergic receptor agonists\/antagonists"
			},
			{
				"name":"07214  beta-Adrenergic receptor agonists\/antagonists"
			},
			{
				"name":"07213  Dopamine receptor agonists\/antagonists"
			},
			{
				"name":"07212  Histamine H1 receptor antagonists"
			},
			{
				"name":"07227  Histamine H2\/H3 receptor agonists\/antagonists"
			},
			{
				"name":"07211  Serotonin receptor agonists\/antagonists"
			},
			{
				"name":"07228  Eicosanoid receptor agonists\/antagonists"
			},
			{
				"name":"07224  Opioid receptor agonists\/antagonists"
			},
			{
				"name":"07229  Angiotensin receptor and endothelin receptor antagonists"
			}
			]
		},
		{
			"name":"Target-based classification: Nuclear receptors",
			"children":[
			{
				"name":"07225  Glucocorticoid and mineralocorticoid receptor agonists\/antagonists"
			},
			{
				"name":"07226  Progesterone, androgen and estrogen receptor agonists\/antagonists"
			},
			{
				"name":"07223  Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists\/antagonists"
			},
			{
				"name":"07222  Peroxisome proliferator-activated receptor (PPAR) agonists"
			}
			]
		},
		{
			"name":"Target-based classification: Ion channels",
			"children":[
			{
				"name":"07221  Nicotinic cholinergic receptor antagonists"
			},
			{
				"name":"07230  GABA-A receptor agonists\/antagonists"
			},
			{
				"name":"07036  Calcium channel blocking drugs"
			},
			{
				"name":"07231  Sodium channel blocking drugs"
			},
			{
				"name":"07232  Potassium channel blocking and opening drugs"
			},
			{
				"name":"07235  N-Methyl-D-aspartic acid (NMDA) receptor antagonists"
			}
			]
		},
		{
			"name":"Target-based classification: Transporters",
			"children":[
			{
				"name":"07233  Ion transporter inhibitors"
			},
			{
				"name":"07234  Neurotransmitter transporter inhibitors"
			}
			]
		},
		{
			"name":"Target-based classification: Enzymes",
			"children":[
			{
				"name":"07216  Catecholamine transferase inhibitors"
			},
			{
				"name":"07219  Cyclooxygenase inhibitors"
			},
			{
				"name":"07024  HMG-CoA reductase inhibitors"
			},
			{
				"name":"07217  Renin-angiotensin system inhibitors"
			},
			{
				"name":"07218  HIV protease inhibitors"
			}
			]
		},
		{
			"name":"Structure-based classification",
			"children":[
			{
				"name":"07025  Quinolines"
			},
			{
				"name":"07034  Eicosanoids"
			},
			{
				"name":"07035  Prostaglandins"
			}
			]
		},
		{
			"name":"Skeleton-based classification",
			"children":[
			{
				"name":"07110  Benzoic acid family"
			},
			{
				"name":"07112  1,2-Diphenyl substitution family"
			},
			{
				"name":"07114  Naphthalene family"
			},
			{
				"name":"07117  Benzodiazepine family"
			}
			]
		}
		]
	}
	]
}