ENTRY       R01196                      Reaction
NAME        pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)
DEFINITION  2 Reduced ferredoxin + Acetyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + Pyruvate + CoA
EQUATION    2 C00138 + C00024 + C00011 + 2 C00080 <=> 2 C00139 + C00022 + C00010
RCLASS      RC00004  C00010_C00024
            RC02742  C00022_C00024
ENZYME      1.2.7.1         1.2.7.11
PATHWAY     rn00010  Glycolysis / Gluconeogenesis
            rn00020  Citrate cycle (TCA cycle)
            rn00620  Pyruvate metabolism
            rn00650  Butanoate metabolism
            rn00680  Methane metabolism
            rn00720  Other carbon fixation pathways
            rn01100  Metabolic pathways
            rn01110  Biosynthesis of secondary metabolites
            rn01120  Microbial metabolism in diverse environments
            rn01200  Carbon metabolism
            rn01210  2-Oxocarboxylic acid metabolism
MODULE      M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
            M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
            M00374  Dicarboxylate-hydroxybutyrate cycle
            M00620  Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
BRITE       Enzymatic reactions [BR:br08201]
             1. Oxidoreductase reactions
              1.2  Acting on the aldehyde or oxo group of donors
               1.2.7  With an iron-sulfur protein as acceptor
                1.2.7.1
                 R01196  2 Reduced ferredoxin + Acetyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + Pyruvate + CoA
                1.2.7.11
                 R01196  2 Reduced ferredoxin + Acetyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + Pyruvate + CoA
            IUBMB reaction hierarchy [BR:br08202]
             1. Oxidoreductase reactions
              1.2.7.11
               R10516
                R01196  Pyruvate <=> Acetyl-CoA
            Overall reaction [br08210.html]
             Carbon fixation
              R01196
ORTHOLOGY   K00169  pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
            K00170  pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
            K00171  pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
            K00172  pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
            K00174  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
            K00175  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
            K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
            K03737  pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]
DBLINKS     RHEA: 12768 44143
///