ENTRY       R00342                      Reaction
NAME        (S)-malate:NAD+ oxidoreductase
DEFINITION  (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+
EQUATION    C00149 + C00003 <=> C00036 + C00004 + C00080
RCLASS      RC00001  C00003_C00004
            RC00031  C00036_C00149
ENZYME      1.1.1.37        1.1.1.299
PATHWAY     rn00020  Citrate cycle (TCA cycle)
            rn00620  Pyruvate metabolism
            rn00630  Glyoxylate and dicarboxylate metabolism
            rn00680  Methane metabolism
            rn00710  Carbon fixation by Calvin cycle
            rn00720  Other carbon fixation pathways
            rn01100  Metabolic pathways
            rn01110  Biosynthesis of secondary metabolites
            rn01120  Microbial metabolism in diverse environments
            rn01200  Carbon metabolism
MODULE      M00009  Citrate cycle (TCA cycle, Krebs cycle)
            M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
            M00012  Glyoxylate cycle
            M00168  CAM (Crassulacean acid metabolism), dark
            M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
            M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
            M00346  Formaldehyde assimilation, serine pathway
            M00374  Dicarboxylate-hydroxybutyrate cycle
            M00620  Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
            M00740  Methylaspartate cycle
            M00982  Methylcitrate cycle
BRITE       Enzymatic reactions [BR:br08201]
             1. Oxidoreductase reactions
              1.1  Acting on the CH-OH group of donors
               1.1.1  With NAD+ or NADP+ as acceptor
                1.1.1.37
                 R00342  (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+
                1.1.1.299
                 R00342  (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+
            Overall reaction [br08210.html]
             Carbon fixation
              R00342
ORTHOLOGY   K00024  malate dehydrogenase [EC:1.1.1.37]
            K00025  malate dehydrogenase [EC:1.1.1.37]
            K00026  malate dehydrogenase [EC:1.1.1.37]
DBLINKS     RHEA: 21435
///