ENTRY M00875 Pathway Module NAME Staphyloferrin B biosynthesis, L-serine => staphyloferrin B DEFINITION K23371 K21949 K21721 K23372 K23373 K23374 K23375 DIAGRAM M00875 Staphyloferrin B biosynthesis, L-serine => staphyloferrin B CLASS Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other bacterial compounds PATHWAY map00975 Biosynthesis of various siderophores map01100 Metabolic pathways map01110 Biosynthesis of secondary metabolites ORTHOLOGY K23371 sbnI; L-serine kinase (ATP) / ParB family transcriptional regulator, heme-responsive regulator [EC:2.7.1.225] [RN:R12344] K21949 sbnA; N-(2-amino-2-carboxyethyl)-L-glutamate synthase [EC:2.5.1.140] [RN:R11705] K21721 sbnB; N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase [EC:1.5.1.51] [RN:11655] K23372 sbnE; L-2,3-diaminopropanoate---citrate ligase [EC:6.3.2.54] [RN:R12308] K23373 sbnH; 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase [EC:4.1.1.117] [RN:R12309] K23374 sbnF; 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase [EC:6.3.2.55] [RN:R12311] K23375 sbnC; staphyloferrin B synthase [EC:6.3.2.56] [RN:R12312] COMPLETE pcal Parageobacillus caldoxylosilyticus sau Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) sav Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA) saw Staphylococcus aureus subsp. aureus Mu3 (MRSA/hetero-VISA) sah Staphylococcus aureus subsp. aureus JH1 (MRSA/VSSA) saj Staphylococcus aureus subsp. aureus JH9 (MRSA/VISA) sam Staphylococcus aureus subsp. aureus MW2 (CA-MRSA) sas Staphylococcus aureus subsp. aureus MSSA476 (MSSA) sar Staphylococcus aureus subsp. aureus MRSA252 (MRSA) sac Staphylococcus aureus subsp. aureus COL (MRSA) sax Staphylococcus aureus subsp. aureus USA300_TCH1516 (CA-MRSA) saa Staphylococcus aureus subsp. aureus USA300_FPR3757 (CA-MRSA) sao Staphylococcus aureus subsp. aureus NCTC8325 sae Staphylococcus aureus subsp. aureus Newman sad Staphylococcus aureus subsp. aureus ED98 suu Staphylococcus aureus subsp. aureus M013 (CA-MRSA) suv Staphylococcus aureus subsp. aureus VC40 sue Staphylococcus aureus subsp. aureus ED133 suj Staphylococcus aureus subsp. aureus JKD6159 (CA-MRSA) suk Staphylococcus aureus subsp. aureus JKD6008 (MRSA/VISA) suc Staphylococcus aureus subsp. aureus ECT-R 2 (MSSA) sut Staphylococcus aureus subsp. aureus T0131 (MRSA) suq Staphylococcus aureus subsp. aureus TCH60 suz Staphylococcus aureus subsp. aureus 11819-97 (CA-MRSA) sud Staphylococcus aureus subsp. aureus 71193 (MSSA) sux Staphylococcus aureus subsp. aureus HO 5096 0412 (MRSA) suw Staphylococcus aureus subsp. aureus TW20 (MRSA) sug Staphylococcus aureus subsp. aureus ST398 (MRSA) suf Staphylococcus aureus subsp. aureus LGA251 (MRSA) saua Staphylococcus aureus subsp. aureus 55/2053 saue Staphylococcus aureus subsp. aureus 6850 (MSSA) saun Staphylococcus aureus subsp. aureus CN1 (CA-MRSA) saus Staphylococcus aureus subsp. aureus SA40 (CA-MRSA) sauu Staphylococcus aureus subsp. aureus SA957 (CA-MRSA) saug Staphylococcus aureus subsp. aureus SA268 (CA-MRSA) sauz Staphylococcus aureus subsp. aureus Z172 (MRSA/VISA) saut Staphylococcus aureus subsp. aureus ST228/10388 (MRSA) sauj Staphylococcus aureus subsp. aureus ST228/10497 (MRSA) sauk Staphylococcus aureus subsp. aureus ST228/15532 (MRSA) sauq Staphylococcus aureus subsp. aureus ST228/16035 (MRSA) sauv Staphylococcus aureus subsp. aureus ST228/18412 (MRSA) sauw Staphylococcus aureus subsp. aureus ST228/16125 (MRSA) saux Staphylococcus aureus subsp. aureus ST228/18341 (MRSA) sauy Staphylococcus aureus subsp. aureus ST228/18583 (MRSA) sauf Staphylococcus aureus subsp. aureus FDAARGOS_5 sab Staphylococcus aureus RF122 suy Staphylococcus aureus 04-02981 (MRSA) saub Staphylococcus aureus 08BA02176 (LA-MRSA) saum Staphylococcus aureus M1 (MRSA) sauc Staphylococcus aureus CA-347 (MRSA) saur Staphylococcus aureus Bmb9393 (MRSA) saui Staphylococcus aureus USA300-ISMMS1 (MRSA) saud Staphylococcus aureus 502A sams Staphylococcus aureus MS4 suh Staphylococcus argenteus ssd Staphylococcus pseudintermedius HKU10-03 sdt Staphylococcus pseudintermedius ED99 sdp Staphylococcus delphini shu Staphylococcus hyicus ssch Staphylococcus schleiferi 1360-13 sscz Staphylococcus schleiferi 2317-03 sagq Staphylococcus agnetis seqo Staphylococcus equorum slz Staphylococcus lutrae sarl Staphylococcus arlettae ssh Staphylococcus schweitzeri srai Staphylococcus ratti srot Staphylococcus roterodami stap Staphylococcus sp. AntiMn-1 sff Mammaliicoccus fleurettii bagr Brevibacillus agri tab Tumebacillus algifaecis lfb Laceyella sacchari pabs Polycladomyces abyssicola REACTION R12344 C00065 -> C01005 R11705 C01005 -> C21559 R11655 C21559 -> C03401 R12308 C03401 + C00158 -> C22072 R12309 C22072 -> C22073 R12311 C22073 -> C22074 R12312 C22074 -> C22075 COMPOUND C00065 L-Serine C01005 O-Phospho-L-serine C21559 N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate C03401 L-2,3-Diaminopropanoate C00158 Citrate C22072 2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate C22073 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate C22074 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate C22075 Staphyloferrin B REFERENCE PMID:24485762 AUTHORS Kobylarz MJ, Grigg JC, Takayama SJ, Rai DK, Heinrichs DE, Murphy ME TITLE Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor. JOURNAL Chem Biol 21:379-88 (2014) DOI:10.1016/j.chembiol.2013.12.011 ///