ENTRY D10925 Drug NAME Elamipretide (USAN/INN) FORMULA C32H49N9O5 EXACT_MASS 639.3857 MOL_WEIGHT 639.79 REMARK Chemical structure group: DG03046 Product (DG03046): D11542 EFFICACY Mitochondrial protective COMMENT Oligopeptide Mitochondrial protective agent to improve cell viability TARGET Citochondrial cardiolipin [CPD:C05980] DBLINKS CAS: 736992-21-5 PubChem: 342581782 ChEBI: 233331 ATOM 46 1 N1a N 12.7597 -13.8600 2 C1c C 13.9722 -13.1600 3 C5a C 15.1846 -13.8600 4 N1b N 16.3970 -13.1600 5 C1c C 17.6095 -13.8600 6 C5a C 18.8219 -13.1600 7 N1b N 20.0344 -13.8600 8 C1c C 21.2468 -13.1600 9 C5a C 22.4592 -13.8600 10 N1b N 23.6717 -13.1600 11 C1c C 24.8841 -13.8600 12 C5a C 26.0965 -13.1600 13 N1a N 27.3090 -13.8600 14 O5a O 26.0965 -11.7601 15 C1b C 24.8841 -15.2596 16 C8y C 26.0709 -15.9450 17 C8x C 26.0711 -17.3597 18 C8x C 27.2836 -18.0595 19 C8x C 28.4959 -17.3594 20 C8x C 28.4958 -15.9448 21 C8x C 27.2833 -15.2449 22 O5a O 22.4592 -15.2600 23 C1b C 21.2468 -11.7604 24 O5a O 18.8219 -11.7600 25 C1b C 22.4870 -11.0507 26 C1b C 22.4763 -9.6508 27 C1b C 23.6833 -8.9415 28 N1a N 23.6726 -7.5415 29 C1b C 17.6095 -16.6597 30 C8y C 18.8447 -17.3732 31 C8y C 18.8443 -18.7599 32 C8x C 20.0566 -19.4603 33 C8y C 21.2692 -18.7606 34 C8x C 21.2696 -17.3739 35 C8y C 20.0574 -16.6735 36 O1a O 22.4892 -19.4656 37 C1a C 17.6209 -19.4658 38 C1a C 20.0575 -15.2604 39 O5a O 15.1846 -15.2600 40 C1b C 13.9722 -11.7603 41 C1b C 15.2093 -11.0546 42 C1b C 15.2031 -9.6546 43 N1b N 16.4124 -8.9492 44 C2c C 16.4061 -7.5492 45 N1a N 17.6155 -6.8439 46 N2a N 15.1758 -6.8459 BOND 47 1 1 2 1 2 2 3 1 3 3 4 1 4 4 5 1 5 5 6 1 6 6 7 1 7 7 8 1 8 8 9 1 9 9 10 1 10 10 11 1 11 11 12 1 12 12 13 1 13 12 14 2 14 11 15 1 #Down 15 15 16 1 16 16 17 2 17 17 18 1 18 18 19 2 19 19 20 1 20 20 21 2 21 16 21 1 22 9 22 2 23 8 23 1 #Up 24 6 24 2 25 23 25 1 26 25 26 1 27 26 27 1 28 27 28 1 29 5 29 1 #Down 30 29 30 1 31 30 31 2 32 31 32 1 33 32 33 2 34 33 34 1 35 34 35 2 36 30 35 1 37 33 36 1 38 31 37 1 39 35 38 1 40 3 39 2 41 2 40 1 #Down 42 40 41 1 43 41 42 1 44 42 43 1 45 43 44 1 46 44 45 1 47 44 46 2 ///