ENTRY D08125 Drug NAME Levothyroxine (BAN); Forthyron (TN) FORMULA C15H11I4NO4 EXACT_MASS 776.6867 MOL_WEIGHT 776.87 CLASS Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher REMARK Same as: C01829 Chemical structure group: DG00510 Product (DG00510): D01010 D11113 EFFICACY Replenisher (thyroid hormone) TARGET NR1A (THR) [HSA:7067 7068] [KO:K05547 K08362] PATHWAY hsa04080(7067+7068) Neuroactive ligand-receptor interaction hsa04919(7067+7068) Thyroid hormone signaling pathway INTERACTION STR_MAP map07043 Antineoplastics - hormones BRITE Drug groups [BR:br08330] Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher DG00510 Levothyroxine D08125 Levothyroxine Target-based classification of drugs [BR:br08310] Nuclear receptors Thyroid hormone like receptors Thyroid hormone receptor (THR) NR1A (THR) D08125 Levothyroxine (BAN) Drug groups [BR:br08330] Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher DG00510 Levothyroxine DBLINKS CAS: 51-48-9 PubChem: 96024815 ChEBI: 18332 PDB-CCD: T44 LigandBox: D08125 J-GLOBAL: J4.118A ATOM 24 1 C8y C 27.0900 -18.6200 2 O2a O 25.9000 -17.9200 3 C8x C 27.0900 -20.0200 4 C8x C 28.3500 -17.9200 5 C8y C 24.7100 -17.2200 6 C8y C 28.3500 -20.7200 7 C8y C 29.5400 -18.6200 8 C8y C 23.5200 -17.9200 9 C8y C 24.7100 -15.8200 10 C8y C 29.5400 -20.0200 11 X I 28.3500 -22.1200 12 X I 30.7300 -17.8500 13 C8x C 22.2600 -17.2200 14 X I 23.5200 -19.3200 15 C8x C 23.5200 -15.1200 16 X I 25.9000 -15.1200 17 O1a O 30.8000 -20.6500 18 C8y C 22.2600 -15.8200 19 C1b C 21.0700 -15.1200 20 C1c C 19.8800 -15.8200 21 C6a C 18.6900 -15.1200 22 N1a N 19.8800 -17.2200 23 O6a O 18.6900 -13.7200 24 O6a O 17.5000 -15.8200 BOND 25 1 1 2 1 2 1 3 2 3 1 4 1 4 2 5 1 5 3 6 1 6 4 7 2 7 5 8 1 8 5 9 2 9 6 10 2 10 6 11 1 11 7 12 1 12 8 13 2 13 8 14 1 14 9 15 1 15 9 16 1 16 10 17 1 17 13 18 1 18 18 19 1 19 19 20 1 20 20 21 1 21 20 22 1 #Down 22 21 23 2 23 21 24 1 24 7 10 1 25 15 18 2 ///