ENTRY D03246 Drug NAME Mecobalamin (JP19/USAN); Adestolmin (TN) FORMULA C62H88N13O14P. Co. CH3 EXACT_MASS 1343.5878 MOL_WEIGHT 1344.38 REMARK Same as: C06453 Therapeutic category: 1190 3136 ATC code: B03BA05 Product: D03246 EFFICACY Hematinic, Peripheral neuropathy agent, Supplement (vitamin B12) BRITE Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] B BLOOD AND BLOOD FORMING ORGANS B03 ANTIANEMIC PREPARATIONS B03B VITAMIN B12 AND FOLIC ACID B03BA Vitamin B12 (cyanocobalamin and analogues) B03BA05 Mecobalamin D03246 Mecobalamin (JP19/USAN) <JP> Therapeutic category of drugs in Japan [BR:br08301] 1 Agents affecting nervous system and sensory organs 11 Agents affecting central nervous system 119 Miscellaneous 1190 Miscellaneous D03246 Mecobalamin (JP19/USAN) 3 Agents affecting metabolism 31 Vitamins 313 Vitamin B preparations 3136 Vitamin B12 preparations D03246 Mecobalamin (JP19/USAN) Classification of Japanese OTC drugs [BR:br08313] Nourishing tonics and health supplements 42 Vitamin B1B6B12 based drugs D03246 Mecobalamin (JP19/USAN) Risk category of Japanese OTC drugs [BR:br08312] Third-class OTC drugs Inorganic and organic chemicals Mecobalamin D03246 Mecobalamin (JP19/USAN) Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D03246 Mecobalamin D03246 Mecobalamin tablets Rx-to-OTC switch list in Japan [br08314.html] D03246 DBLINKS CAS: 13422-55-4 PubChem: 17397399 ChEBI: 28115 J-GLOBAL: J1.706.550E ATOM 92 1 N2x N 3.4519 -10.0843 2 N1x N 3.3069 -11.6708 #- 3 N2x N 5.1468 -10.1134 4 N2x N 5.1280 -11.7404 5 N5x N 5.1246 -16.2379 6 C1z C 2.6838 -10.2149 7 C2y C 3.5853 -9.3237 8 C1y C 2.6838 -11.6464 9 C2y C 3.5819 -12.5259 10 C2y C 4.9886 -9.3492 11 C2y C 5.9260 -10.1894 12 C2y C 4.9920 -12.5011 13 C2y C 5.9114 -11.6353 14 C8y C 5.8534 -16.4721 15 C8x C 4.6818 -16.8694 16 C1z C 2.3232 -9.5074 17 C1a C 1.9148 -10.4201 18 C1y C 2.8855 -8.9596 19 C2y C 4.2845 -9.0605 20 C1y C 2.3232 -12.3463 21 C1z C 2.8855 -12.8906 22 C2y C 4.2845 -12.8002 23 C1z C 5.6704 -8.9630 24 C1y C 6.2431 -9.4750 25 C2x C 6.2217 -10.9107 26 C1y C 5.6773 -12.8803 27 C1z C 6.2507 -12.3463 28 C8y C 5.8569 -17.2362 29 C8x C 6.5243 -16.0935 30 N4y N 5.1246 -17.4780 31 C1b C 1.5438 -9.4998 32 C1a C 2.1097 -8.7544 33 C1b C 2.9042 -8.1845 34 C1a C 4.2810 -8.2633 35 C1b C 1.4720 -12.3429 36 C1b C 2.8820 -13.6658 37 C1a C 3.6239 -13.0890 38 C1a C 4.2810 -13.5905 39 C1b C 5.6669 -8.1734 40 C1b C 7.0182 -9.4674 41 C1b C 5.7526 -13.6589 42 C1a C 6.9969 -12.1397 43 C1a C 6.5353 -13.0779 44 C8x C 6.5243 -17.6300 45 C8y C 7.1959 -16.4721 46 C1y C 2.3985 -19.4263 47 C5a C 1.1583 -8.8255 48 C1b C 2.2292 -7.7872 49 C5a C 1.1901 -13.0710 50 C1b C 2.1967 -14.0665 51 C5a C 6.3295 -7.7768 52 C1b C 7.4079 -8.7897 53 C1b C 6.4636 -13.9795 54 C8y C 7.1959 -17.2362 55 C1a C 7.8556 -16.0970 56 C1y C 2.1635 -18.6982 57 O2x O 1.7310 -19.8050 58 N1a N 0.3824 -8.8221 59 O5a O 1.1333 -7.9756 60 C5a C 2.2326 -7.0122 61 N1a N 0.4260 -13.1898 62 O5a O 1.6806 -13.6624 63 C5a C 2.1891 -14.8486 64 N1a N 6.3295 -7.0066 65 O5a O 7.0113 -8.1699 66 C5a C 8.1831 -8.7862 67 C5a C 6.5430 -14.7553 68 C1a C 7.8556 -17.6300 69 C1y C 1.4036 -18.6829 70 O1a O 2.6257 -18.0735 71 C1y C 1.1583 -19.4075 72 N1a N 1.5652 -6.6129 73 O5a O 2.9180 -6.6276 74 N1b N 1.5072 -15.2348 75 O5a O 2.8640 -15.2458 76 N1a N 8.5845 -8.1043 77 O5a O 8.5914 -9.4640 78 N1a N 5.9004 -15.2065 79 O5a O 7.2566 -15.0801 80 O2b O 0.9517 -18.0556 81 C1b C 0.3755 -19.6750 82 C1b C 1.5149 -16.0389 83 P1b P 0.0936 -17.6770 84 O1a O 0.2636 -20.2022 85 C1c C 0.8156 -16.4542 86 O2b O 0.8156 -17.2583 87 O1c O -0.6200 -17.2583 #- 88 O1c O -0.4866 -18.2615 89 C1a C 0.1151 -16.0466 90 C1a C 4.9500 -8.5500 91 Z Co 4.0167 -10.9292 #3+ 92 C0 C 7.7708 -10.8458 #- BOND 97 1 1 6 1 2 1 7 2 3 2 8 1 4 2 9 1 5 3 10 1 6 3 11 2 7 4 12 2 8 4 13 1 9 5 14 1 10 5 15 2 11 6 16 1 12 6 17 1 #Down 13 7 18 1 14 7 19 1 15 8 20 1 16 9 21 1 17 9 22 2 18 10 23 1 19 11 24 1 20 11 25 1 21 12 26 1 22 13 27 1 23 14 28 2 24 14 29 1 25 15 30 1 26 16 31 1 #Up 27 16 32 1 #Down 28 18 33 1 #Down 29 19 34 1 30 20 35 1 #Up 31 21 36 1 #Down 32 21 37 1 #Up 33 22 38 1 34 23 39 1 #Up 35 24 40 1 #Down 36 26 41 1 #Down 37 27 42 1 38 27 43 1 39 28 44 1 40 29 45 2 41 30 46 1 42 31 47 1 43 33 48 1 44 35 49 1 45 36 50 1 46 39 51 1 47 40 52 1 48 41 53 1 49 44 54 2 50 45 55 1 51 46 56 1 52 46 57 1 #Up 53 47 58 1 54 47 59 2 55 48 60 1 56 49 61 1 57 49 62 2 58 50 63 1 59 51 64 1 60 51 65 2 61 52 66 1 62 53 67 1 63 54 68 1 64 56 69 1 65 56 70 1 66 71 57 1 #Up 67 60 72 1 68 60 73 2 69 63 74 1 70 63 75 2 71 66 76 1 72 66 77 2 73 67 78 1 74 67 79 2 75 69 80 1 76 71 81 1 77 74 82 1 78 80 83 1 79 81 84 1 80 82 85 1 81 83 86 1 82 83 87 1 83 83 88 2 84 85 89 1 85 6 8 1 86 10 19 2 87 12 22 1 88 13 25 2 89 16 18 1 90 20 21 1 91 23 24 1 92 26 27 1 93 28 30 1 94 45 54 1 95 69 71 1 96 85 86 1 97 23 90 1 #Down ///