ENTRY D01010 Drug NAME Levothyroxine sodium (USP); Levothyroxine sodium hydrate (JP19); Levothroid (TN); Levoxyl (TN); Synthroid (TN) PRODUCT EUTHYROX (Provell Pharmaceuticals) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (Alvogen) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (DIRECT RX) LEVOTHYROXINE SODIUM (Fresenius Kabi USA) LEVOTHYROXINE SODIUM (NCS HealthCare of KY) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (NuCar Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOXYL (Pfizer Laboratories Div Pfizer) SYNTHROID (AbbVie) THYQUIDITY (Oliva Therapeutics) TIROSINT (IBSA Pharma) TIROSINT (IBSA Pharma) UNITHROID (Amneal Pharmaceuticals LLC) GENERIC LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (A-S Medication Solutions) LEVOTHYROXINE SODIUM (ASCLEMED USA) LEVOTHYROXINE SODIUM (Accord Healthcare) LEVOTHYROXINE SODIUM (American Health Packaging) LEVOTHYROXINE SODIUM (Amneal Pharmaceuticals NY LLC) LEVOTHYROXINE SODIUM (Aurobindo Pharma Limited) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Bryant Ranch Prepack) LEVOTHYROXINE SODIUM (Camber Pharmaceuticals) LEVOTHYROXINE SODIUM (Cardinal Health 107) LEVOTHYROXINE SODIUM (Cardinal Health 107) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Coupler LLC) LEVOTHYROXINE SODIUM (Direct Rx) LEVOTHYROXINE SODIUM (Direct_Rx) LEVOTHYROXINE SODIUM (Direct_rx) LEVOTHYROXINE SODIUM (Lannett Company) LEVOTHYROXINE SODIUM (Lupin Pharmaceuticals) LEVOTHYROXINE SODIUM (Macleods Pharmaceuticals Limited) LEVOTHYROXINE SODIUM (Major Pharmaceuticals) LEVOTHYROXINE SODIUM (Mylan Institutional) LEVOTHYROXINE SODIUM (Mylan Institutional) LEVOTHYROXINE SODIUM (Mylan Pharmaceuticals) LEVOTHYROXINE SODIUM (NorthStar RxLLC) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (Northwind Health Company) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCare Pharmaceuticals) LEVOTHYROXINE SODIUM (NuCarePharmaceuticals) LEVOTHYROXINE SODIUM (PD-Rx Pharmaceuticals) LEVOTHYROXINE SODIUM (PD-Rx Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Preferred Pharmaceuticals) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (Proficient Rx LP) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (REMEDYREPACK) LEVOTHYROXINE SODIUM (RedPharm Drug) LEVOTHYROXINE SODIUM (Redpharm drug) LEVOTHYROXINE SODIUM (Redpharm drug) LEVOTHYROXINE SODIUM (Teva Pharmaceuticals) LEVOTHYROXINE SODIUM (XLCare Pharmaceuticals) LEVOTHYROXINE SODIUM (YARAL Pharma) FORMULA C15H10I4NO4. Na. xH2O CLASS Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher REMARK Therapeutic category: 2431 ATC code: H03AA01 Chemical structure group: DG00510 Product (DG00510): D01010 D11113 EFFICACY Replenisher (thyroid hormone) DISEASE Hypothyroidism [DS:H00250] Hashimoto's thyroiditis [DS:H00081] TARGET NR1A (THR) [HSA:7067 7068] [KO:K05547 K08362] PATHWAY hsa04080(7067+7068) Neuroactive ligand-receptor interaction hsa04919(7067+7068) Thyroid hormone signaling pathway NETWORK nt06322 TRH-TSH-TH signaling INTERACTION STR_MAP map07043 Antineoplastics - hormones BRITE Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS H03 THYROID THERAPY H03A THYROID PREPARATIONS H03AA Thyroid hormones H03AA01 Levothyroxine sodium D01010 Levothyroxine sodium (USP) <JP/US> USP drug classification [BR:br08302] Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid) Levothyroxine D01010 Levothyroxine sodium (USP) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 24 Hormones 243 Thyroid and parathyroid hormone preparations 2431 Thyroid hormones D01010 Levothyroxine sodium (USP); Levothyroxine sodium hydrate (JP19) Drug groups [BR:br08330] Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher DG00510 Levothyroxine D01010 Levothyroxine sodium Target-based classification of drugs [BR:br08310] Nuclear receptors Thyroid hormone like receptors Thyroid hormone receptor (THR) NR1A (THR) D01010 Levothyroxine sodium (USP) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D01010 Levothyroxine sodium hydrate D01010 Levothyroxine sodium tablets Drug groups [BR:br08330] Hormonal agent DG01953 Thyroid preparation DG01608 Thyroid hormone replenisher DG00510 Levothyroxine DBLINKS CAS: 25416-65-3 PubChem: 7848073 ChEBI: 6447 LigandBox: D01010 ATOM 26 1 C8y C 28.4332 -19.6165 2 O2a O 27.2285 -18.9148 3 C8x C 28.4449 -21.0082 4 C8x C 29.6494 -18.8914 5 C8y C 26.0357 -18.2073 6 C8y C 29.6611 -21.6865 7 C8y C 30.8657 -19.5697 8 C8y C 24.8253 -18.9090 9 C8y C 26.0357 -16.7980 10 C8y C 30.8774 -20.9731 11 X I 29.6787 -23.0782 12 X I 32.0645 -18.8505 13 C8x C 23.6208 -18.2073 14 X I 24.8370 -20.3239 15 C8x C 24.8253 -16.0905 16 X I 27.2462 -16.0846 17 O1a O 32.0996 -21.6514 18 C8y C 23.6208 -16.7980 19 C1b C 22.4221 -16.0846 20 C1c C 21.2234 -16.7863 21 C6a C 20.0246 -16.0788 22 N1a N 21.2351 -18.2014 23 O6a O 20.0304 -14.6696 24 O6a O 18.8200 -16.7805 #- 25 O0 O 36.2757 -20.2436 26 Z Na 15.7495 -16.8712 #+ BOND 25 1 1 2 1 2 1 3 2 3 1 4 1 4 2 5 1 5 3 6 1 6 4 7 2 7 5 8 1 8 5 9 2 9 6 10 2 10 6 11 1 11 7 12 1 12 8 13 2 13 8 14 1 14 9 15 1 15 9 16 1 16 10 17 1 17 13 18 1 18 18 19 1 19 19 20 1 20 20 21 1 21 20 22 1 #Down 22 21 23 2 23 21 24 1 24 7 10 1 25 15 18 2 BRACKET 1 34.3700 -21.3500 34.3700 -19.0400 1 36.8200 -19.0400 36.8200 -21.3500 1 x ORIGINAL 1 25 REPEAT 1 ///