ENTRY C00149 Compound NAME (S)-Malate; L-Malate; L-Apple acid; L-Malic acid; L-2-Hydroxybutanedioic acid; Malate; Malic acid FORMULA C4H6O5 EXACT_MASS 134.0215 MOL_WEIGHT 134.09 REACTION R00214 R00216 R00342 R00343 R00360 R00361 R00406 R00472 R01082 R01256 R01257 R01447 R03323 R10612 R11074 PATHWAY map00020 Citrate cycle (TCA cycle) map00620 Pyruvate metabolism map00630 Glyoxylate and dicarboxylate metabolism map00680 Methane metabolism map00710 Carbon fixation by Calvin cycle map00720 Other carbon fixation pathways map01060 Biosynthesis of plant secondary metabolites map01061 Biosynthesis of phenylpropanoids map01062 Biosynthesis of terpenoids and steroids map01063 Biosynthesis of alkaloids derived from shikimate pathway map01064 Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid map01065 Biosynthesis of alkaloids derived from histidine and purine map01066 Biosynthesis of alkaloids derived from terpenoid and polyketide map01070 Biosynthesis of plant hormones map01100 Metabolic pathways map01110 Biosynthesis of secondary metabolites map01120 Microbial metabolism in diverse environments map01200 Carbon metabolism map02020 Two-component system map04742 Taste transduction map04922 Glucagon signaling pathway map04964 Proximal tubule bicarbonate reclamation map05200 Pathways in cancer map05211 Renal cell carcinoma map05230 Central carbon metabolism in cancer MODULE M00009 Citrate cycle (TCA cycle, Krebs cycle) M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate M00012 Glyoxylate cycle M00168 CAM (Crassulacean acid metabolism), dark M00169 CAM (Crassulacean acid metabolism), light M00171 C4-dicarboxylic acid cycle, NAD - malic enzyme type M00172 C4-dicarboxylic acid cycle, NADP - malic enzyme type M00173 Reductive citrate cycle (Arnon-Buchanan cycle) M00346 Formaldehyde assimilation, serine pathway M00373 Ethylmalonyl pathway M00374 Dicarboxylate-hydroxybutyrate cycle M00376 3-Hydroxypropionate bi-cycle M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate M00740 Methylaspartate cycle M00982 Methylcitrate cycle ENZYME 1.1.1.37 1.1.1.38 1.1.1.39 1.1.1.40 1.1.1.82 1.1.1.299 1.1.5.4 1.1.99.7 2.3.1.92 2.3.3.9 2.8.3.22 3.1.2.30 4.1.1.101 4.2.1.2 6.2.1.9 BRITE Compounds with biological roles [BR:br08001] Organic acids Carboxylic acids Hydroxycarboxylic acids C00149 Malate; (S)-2-Hydroxybutanediate DBLINKS CAS: 97-67-6 PubChem: 3449 ChEBI: 15589 30797 KNApSAcK: C00001192 PDB-CCD: LMR J-GLOBAL: J74.430A ATOM 9 1 C1c C 25.0942 -18.6205 2 C1b C 26.2953 -19.3132 3 C6a C 23.8998 -19.3132 4 O1a O 25.0942 -17.2355 5 C6a C 27.4897 -18.6205 6 O6a O 22.7052 -18.6143 7 O6a O 23.8360 -20.8303 8 O6a O 28.6842 -19.3132 9 O6a O 27.4834 -17.2355 BOND 8 1 1 2 1 2 1 3 1 3 1 4 1 #Up 4 2 5 1 5 3 6 1 6 3 7 2 7 5 8 1 8 5 9 2 ///