R00001 polyphosphate polyphosphohydrolase; Polyphosphate + n H2O <=> (n+1) Oligophosphate R00002 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + 16 H2O + 8 Reduced ferredoxin <=> 8 e- + 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin R00004 diphosphate phosphohydrolase; pyrophosphate phosphohydrolase; Diphosphate + H2O <=> 2 Orthophosphate R00005 urea-1-carboxylate amidohydrolase; Urea-1-carboxylate + H2O <=> 2 CO2 + 2 Ammonia R00006 pyruvate:pyruvate acetaldehydetransferase (decarboxylating); 2-acetolactate pyruvate-lyase (carboxylating); 2-Acetolactate + CO2 <=> 2 Pyruvate R00008 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming); Parapyruvate <=> 2 Pyruvate R00009 hydrogen-peroxide:hydrogen-peroxide oxidoreductase; 2 Hydrogen peroxide <=> Oxygen + 2 H2O R00010 alpha,alpha-trehalose glucohydrolase; alpha,alpha-Trehalose + H2O <=> 2 D-Glucose R00011 Mn(II):hydrogen-peroxide oxidoreductase; 2 Manganese(2+) + Hydrogen peroxide + 2 H+ <=> 2 Manganese(3+) + 2 H2O R00012 GTP:GTP guanylyltransferase; 2 GTP <=> Diphosphate + P1,P4-Bis(5'-guanosyl) tetraphosphate R00013 glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming); 2 Glyoxylate <=> 2-Hydroxy-3-oxopropanoate + CO2 R00014 pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating); Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2 R00015 sucrose:sucrose 1'-beta-D-fructosyltransferase; sucrose:sucrose 1F-beta-D-fructosyltransferase; 2 Sucrose <=> D-Glucose + 1F-beta-D-Fructosylsucrose R00017 ferrocytochrome-c:hydrogen-peroxide oxidoreductase; Hydrogen peroxide + 2 Ferrocytochrome c <=> 2 Ferricytochrome c + 2 H2O R00018 putrescine:putrescine 4-aminobutyltransferase (ammonia-forming); 2 Putrescine <=> sym-Homospermidine + Ammonia R00019 hydrogen:ferredoxin oxidoreductase; reduced ferredoxin:H+ oxidoreductase; 2 Reduced ferredoxin + 2 H+ <=> Hydrogen + 2 Oxidized ferredoxin R00021 L-glutamate:ferredoxin oxidoreductase (transaminating); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin + 2 H+ R00022 chitobiose N-acetylglucosaminohydrolase; Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine R00023 hydroxylamine:NAD+ oxidoreductase; NADH:hyponitrite oxidoreductase; 2 Hydroxylamine + 2 NAD+ <=> Hyponitrite + 2 NADH + 2 H+ R00024 3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming); D-Ribulose 1,5-bisphosphate + CO2 + H2O <=> 2 3-Phospho-D-glycerate R00025 ethylnitronate:oxygen 2-oxidoreductase (nitrite-forming); Ethylnitronate + Oxygen + Reduced FMN <=> Acetaldehyde + Nitrite + FMN + H2O R00026 cellobiose glucohydrolase; Cellobiose + H2O <=> 2 beta-D-Glucose R00027 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming); Benzoin <=> 2 Benzaldehyde R00028 maltose glucohydrolase; Maltose + H2O <=> 2 D-Glucose R00029 thiosulfate:ferricytochrome-c oxidoreductase; 2 Thiosulfate + 2 Ferricytochrome c <=> Tetrathionate + 2 Ferrocytochrome c R00031 1,2-benzenediol:oxygen oxidoreductase; Oxygen + 2 L-Tyrosine <=> 2 3,4-Dihydroxy-L-phenylalanine R00032 beta-carotene:oxygen 15,15'-oxidoreductase (bond-cleaving); beta-Carotene + Oxygen <=> 2 Retinal R00033 thiamine:oxygen 5-oxidoreductase; Thiamine + Oxygen <=> Hydrogen peroxide + Thiamine aldehyde R00034 cyclobutadipyrimidine (in DNA) pyrimidine-lyase; Cyclobutadipyrimidine <=> 2 Pyrimidine 5'-deoxynucleotide R00036 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming); 2 5-Aminolevulinate <=> Porphobilinogen + 2 H2O R00038 4-hydroxy-3-hexanone propanal-lyase (propanal-forming); 2 Propanal <=> 4-Hydroxyhexan-3-one R00039 raffinose:raffinose 1F-alpha-D-galactosyltransferase; 2 Raffinose <=> Lychnose + Sucrose R00041 long-chain-alcohol:oxygen oxidoreductase; 2 Long-chain alcohol + Oxygen <=> 2 Long-chain aldehyde + 2 H2O R00042 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating); 2 3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> 2 4-Hydroxyphenylacetate + 2 CO2 R00043 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alpha-beta-bond-cleaving); 1,2-Bis(4-hydroxy-3-methoxyphenyl)ethylene + Oxygen <=> 2 4-Hydroxy-3-methoxy-benzaldehyde R00044 columbamine:oxygen oxidoreductase (cyclizing); 2 Columbamine + Oxygen <=> 2 Berberine + 2 H2O R00045 3,4-dihydroxy-L-phenylalanine:oxygen oxidoreductase; Oxygen + 2 3,4-Dihydroxy-L-phenylalanine <=> 2 Dopaquinone + 2 H2O R00047 6-hydroxynicotinate,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating, decarboxylating); Oxygen + 6-Hydroxynicotinate + Reduced acceptor <=> 2,5-Dihydroxypyridine + CO2 + Acceptor + H2O R00048 (R)-3-((R)-3-hydroxybutanoyloxy)-butanoate hydroxybutanoylhydrolase; (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate + H2O <=> 2 (R)-3-Hydroxybutanoate R00049 1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase; 2 1-O-Galloyl-beta-D-glucose <=> D-Glucose + 1-O,6-O-Digalloyl-beta-D-glucose R00052 chloride:hydrogen-peroxide oxidoreductase; Hydrogen peroxide + Alkane + Hydrochloric acid <=> RCl + 2 H2O R00053 digallate acylhydrolase; tannin acylhydrolase; Digallate + H2O <=> 2 Gallate R00054 orsellinate-depside hydrolase; Lecanoric acid + H2O <=> 2 Orsellinate R00055 inosine:oxygen 5'-oxidoreductase; 2 Inosine + Oxygen <=> 2 5'-Oxoinosine + 2 H2O R00056 dinucleotide nucleotidohydrolase; Dinucleotide + H2O <=> 2 Mononucleotide R00057 thiol:oxygen oxidoreductase; Oxygen + 2 R'C(R)SH <=> R'C(R)S-S(R)CR' + Hydrogen peroxide R00058 catechol:oxygen oxidoreductase; 1,2-benzenediol:oxygen oxidoreductase; Oxygen + 2 Catechol <=> 2 o-Benzoquinone + 2 H2O R00059 N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase; N-(6-Aminohexanoyl)-6-aminohexanoate + H2O <=> 2 6-Aminohexanoate R00060 sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific); Oxygen + 2 Sulochrin <=> 2 (+)-Bisdechlorogeodin + 2 H2O R00061 sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific); Oxygen + 2 Sulochrin <=> 2 (-)-Bisdechlorogeodin + 2 H2O R00062 bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase; 2 Bilirubin-glucuronoside <=> Bilirubin + Bilirubin beta-diglucuronide R00063 1-O-sinapoyl-beta-D-glucose:1-O-sinapoyl-beta-D-glucose 1-O-sinapoyltransferase; 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase; 2 1-O-Sinapoyl-beta-D-glucose <=> 1,2-Bis-O-sinapoyl-beta-D-glucose + D-Glucose R00066 6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase; 2 6,7-Dimethyl-8-(D-ribityl)lumazine <=> Riboflavin + 5-Amino-6-(1-D-ribitylamino)uracil R00067 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 2 e- + 2 H+ <=> Hydrogen R00068 L-ascorbate:oxygen oxidoreductase; Oxygen + 2 Ascorbate <=> 2 Dehydroascorbate + 2 H2O R00069 4-imidazolone-5-propanoate:oxygen oxidoreductase; Hydantoin-5-propionate + Hydrogen peroxide <=> 4-Imidazolone-5-propanoate + Oxygen + H2O R00070 D-urobilinogen:oxygen oxidoreductase; 2 D-Urobilinogen + Oxygen <=> 2 D-Urobilin + 2 H2O R00072 thiamine-aldehyde:oxygen 5-oxidoreductase; Thiamine aldehyde + Oxygen + H2O <=> Hydrogen peroxide + Thiamine acetic acid R00073 reduced acceptor:prostaglandin G2 oxidoreductase; Prostaglandin H2 + Acceptor + H2O <=> Prostaglandin G2 + Reduced acceptor R00074 2-aminophenol:oxygen oxidoreductase (dimerizing); 4 2-Aminophenol + 3 Oxygen <=> 2 2-Aminophenoxazin-3-one + 6 H2O R00075 S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase; 3 S-Adenosyl-L-methionine <=> 3 5'-Methylthioadenosine + Nicotianamine R00076 ATP:phosphorylase-b phosphotransferase; ATP:[glycogen phosphorylase] phosphotransferase; 4 ATP + 2 Phosphorylase b <=> 4 ADP + Phosphorylase a R00077 [phosphorylase a] phosphohydrolase; [glycogen phosphorylase] phosphohydrolase; Phosphorylase a + 4 H2O <=> 2 Phosphorylase b + 4 Orthophosphate R00078 Fe(II):oxygen oxidoreductase; Fe2+:oxygen oxidoreductase; Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O R00080 catechol:oxygen oxidoreductase (dimerizing); 4 Catechol + 3 Oxygen <=> 6 H2O + 2 Dibenzo[1,4]dioxin-2,3-dione R00081 ferrocytochrome-c:oxygen oxidoreductase; Oxygen + 4 Ferrocytochrome c + 8 H+ <=> 4 Ferricytochrome c + 2 H2O + 4 H+ R00082 ferrocytochrome c2:oxygen oxidoreductase; Oxygen + 4 Ferrocytochrome c2 <=> 4 Ferricytochrome c2 + 2 H2O R00083 benzenediol:oxygen oxidoreductase; Oxygen + 4 Benzenediol <=> 4 Semiquinone + 2 H2O R00084 porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing); porphobilinogen ammonia-lyase (polymerizing); 4 Porphobilinogen + H2O <=> Hydroxymethylbilane + 4 Ammonia R00085 ATP diphosphohydrolase (phosphate-forming); ATP + 2 H2O <=> AMP + 2 Orthophosphate R00086 ATP phosphohydrolase; ATP + H2O <=> ADP + Orthophosphate R00087 ATP diphosphohydrolase (diphosphate-forming); ATP pyrophosphohydrolase; ATP + H2O <=> AMP + Diphosphate R00088 ATP aminohydrolase; ATP + H2O <=> ITP + Ammonia R00089 ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming); ATP <=> 3',5'-Cyclic AMP + Diphosphate R00090 NADH:hydrogen-peroxide oxidoreductase; Hydrogen peroxide + NADH + H+ <=> NAD+ + 2 H2O R00091 CoA:NAD+ oxidoreductase; NAD+ + 2 CoA <=> CoA-disulfide + NADH + H+ R00092 Fe2+:NAD+ oxidoreductase; NADH:Fe3+ oxidoreductase; NAD+ + 2 Fe2+ <=> NADH + H+ + 2 Fe3+ R00093 L-glutamate:NAD+ oxidoreductase (transaminating); 2 L-Glutamate + NAD+ <=> L-Glutamine + 2-Oxoglutarate + NADH + H+ R00094 glutathione:NAD+ oxidoreductase; 2 Glutathione + NAD+ <=> Glutathione disulfide + NADH + H+ R00095 NADH:monodehydroascorbate oxidoreductase; NAD+ + 2 Ascorbate <=> NADH + 2 Monodehydroascorbate + H+ R00097 Cob(II)alamin <=> Aquacob(III)alamin R00099 Cob(I)alamin <=> Cob(II)alamin R00100 NADH:ferricytochrome-b5 oxidoreductase; NADH + 2 Ferricytochrome b5 <=> NAD+ + 2 Ferrocytochrome b5 + H+ R00101 NADH:ferrileghemoglobin oxidoreductase; NADH + 2 Ferrileghemoglobin <=> NAD+ + 2 Ferroleghemoglobin + H+ R00102 NAD+ glycohydrolase; NAD+ + H2O <=> Nicotinamide + ADP-ribose R00103 NAD+ phosphohydrolase; NAD+ + H2O <=> AMP + Nicotinamide D-ribonucleotide R00104 ATP:NAD+ 2'-phosphotransferase; ATP + NAD+ <=> ADP + NADP+ R00105 ATP:NADH 2'-phosphotransferase; ATP + NADH <=> ADP + NADPH R00106 NADPH:ferricytochrome oxidoreductase; NADPH + 2 Ferricytochrome <=> NADP+ + 2 Ferrocytochrome + H+ R00108 NADPH:ferricytochrome-c2 oxidoreductase; NADPH + 2 Ferricytochrome c2 <=> NADP+ + 2 Ferrocytochrome c2 + H+ R00109 NADPH:ferrileghemoglobin oxidoreductase; NADPH + 2 Ferrileghemoglobin <=> NADP+ + 2 Ferroleghemoglobin + H+ R00111 N-(omega)-hydroxyarginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming); NADPH + 2 N(omega)-Hydroxyarginine + 2 Oxygen + H+ <=> NADP+ + 2 Nitric oxide + 2 L-Citrulline + 2 H2O R00112 NADPH:NAD+ oxidoreductase; NADPH + NAD+ <=> NADP+ + NADH R00113 NADPH:hydrogen-peroxide oxidoreductase; Hydrogen peroxide + NADPH + H+ <=> NADP+ + 2 H2O R00114 L-glutamate:NADP+ oxidoreductase (transaminating); 2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+ R00115 glutathione:NADP+ oxidoreductase; 2 Glutathione + NADP+ <=> Glutathione disulfide + NADPH + H+ R00118 NADP+ 2'-phosphohydrolase; NADP+ + H2O <=> Orthophosphate + NAD+ R00119 NADP+:nicotinate ADP-ribosyltransferase; NADP+ + Nicotinate <=> Nicotinamide + Nicotinic acid adenine dinucleotide phosphate R00120 glutathione:oxygen oxidoreductase; Oxygen + 2 Glutathione <=> Glutathione disulfide + Hydrogen peroxide R00122 ADP phosphohydrolase; ADP + H2O <=> AMP + Orthophosphate R00123 ADP aminohydrolase; ADP + H2O <=> IDP + Ammonia R00124 ATP:ADP phosphatransferase; ATP + ADP <=> ADP + ATP R00125 P1,P4-bis(5'-adenosyl)-tetraphosphate nucleotidebisphosphohydrolase; P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> 2 ADP R00126 ADP:ATP adenylyltransferase; ADP + ATP <=> Orthophosphate + P1,P4-Bis(5'-adenosyl)tetraphosphate R00127 ATP:AMP phosphotransferase; ATP + AMP <=> 2 ADP R00128 adenosine-tetraphosphate phosphohydrolase; Adenosine tetraphosphate + H2O <=> ATP + Orthophosphate R00129 (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide hydro-lyase (ATP-hydrolysing, NADH-forming); ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> ADP + Orthophosphate + NADH R00130 ATP:dephospho-CoA 3'-phosphotransferase; ATP + Dephospho-CoA <=> ADP + CoA R00131 urea amidohydrolase; Urea + H2O <=> CO2 + 2 Ammonia R00132 carbonate hydro-lyase (carbon-dioxide-forming); carbonic acid hydro-lyase; Carbonic acid <=> CO2 + H2O R00134 formate:NADP+ oxidoreductase; Formate + NADP+ <=> CO2 + NADPH + H+ R00135 Peptide + H2O <=> L-Proline + Peptide R00137 ATP:nicotinamide-nucleotide adenylyltransferase; ATP + Nicotinamide D-ribonucleotide <=> Diphosphate + NAD+ R00138 triphosphate phosphohydrolase; Triphosphate + H2O <=> Diphosphate + Orthophosphate R00139 ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase; 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP R00140 ATP:5-hydroxymethyldeoxycytidylate phosphotransferase; 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ADP <=> 5-Hydroxymethyldeoxycytidylate + ATP R00141 ATP:ammonia phosphotransferase; ATP + Ammonia <=> ADP + Phosphoramidate R00143 ammonia:NAD+ oxidoreductase; NADH:hydroxylamine oxidoreductase; Ammonia + NAD+ + H2O <=> Hydroxylamine + NADH + H+ R00145 alpha-amino acid:NAD+ oxidoreductase (deaminating); alpha-Amino acid + H2O + NAD+ <=> 2-Oxo acid + Ammonia + NADH + H+ R00146 alpha-amino acid:NADP+ oxidoreductase (deaminating); alpha-Amino acid + H2O + NADP+ <=> 2-Oxo acid + Ammonia + NADPH + H+ R00148 ammonia,ubiquinol:oxygen oxidoreductase; ammonia monooxygenase; Ammonia + Oxygen + Ubiquinol <=> Hydroxylamine + H2O + Ubiquinone R00149 carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating); 2 ATP + Ammonia + CO2 + H2O <=> 2 ADP + Orthophosphate + Carbamoyl phosphate R00150 ATP:carbamate phosphotransferase; ATP + Ammonia + HCO3- <=> ADP + Carbamoyl phosphate + H2O R00152 hydrogen cyanide aminohydrolase; Hydrogen cyanide + 2 H2O <=> Ammonia + Formate R00153 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); Hydrazine + 2 e- + 2 H+ <=> 2 Ammonia R00155 UDP phosphohydrolase; UDP + H2O <=> UMP + Orthophosphate R00156 ATP:UDP phosphotransferase; ATP + UDP <=> ADP + UTP R00157 uridine triphosphate:AMP phosphotransferase; UTP:AMP phosphotransferase; UTP + AMP <=> UDP + ADP R00158 ATP:UMP phosphotransferase; ATP + UMP <=> ADP + UDP R00159 UTP phosphohydrolase; UTP + H2O <=> UDP + Orthophosphate R00160 FAD nucleotidohydrolase; FAD + H2O <=> AMP + FMN R00161 ATP:FMN adenylyltransferase; ATP + FMN <=> Diphosphate + FAD R00162 ATP:protein phosphotransferase; ATP:protein phosphotransferase (Ca2+/calmodulin-dependent); ATP + Protein <=> ADP + Phosphoprotein R00164 phosphoprotein phosphohydrolase; Phosphoprotein + H2O <=> Protein + Orthophosphate R00165 Protein <=> L-Alanyl-tRNA R00166 Protein <=> L-Leucyl-tRNA R00167 L-Arginyl-tRNA(Arg) <=> Protein-L-arginine R00168 Protein <=> L-Valyl-tRNA(Val) R00169 Protein <=> L-Glutamyl-tRNA(Glu) R00170 Protein <=> L-Isoleucyl-tRNA(Ile) R00172 Protein <=> Selenomethionyl-tRNA(Met) R00173 pyridoxal-5'-phosphate phosphohydrolase; Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate R00174 ATP:pyridoxal 5'-phosphotransferase; ATP + Pyridoxal <=> ADP + Pyridoxal phosphate R00177 ATP:L-methionine S-adenosyltransferase; Orthophosphate + Diphosphate + S-Adenosyl-L-methionine <=> ATP + L-Methionine + H2O R00178 S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylsulfanyl)propylamine-forming]; S-Adenosyl-L-methionine + H+ <=> S-Adenosylmethioninamine + CO2 R00179 S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming); S-Adenosyl-L-methionine <=> 1-Aminocyclopropane-1-carboxylate + 5'-Methylthioadenosine R00181 AMP aminohydrolase; AMP + H2O <=> IMP + Ammonia R00182 AMP phosphoribohydrolase; AMP + H2O <=> Adenine + D-Ribose 5-phosphate R00183 adenosine 5'-monophosphate phosphohydrolase; AMP + H2O <=> Adenosine + Orthophosphate R00184 P1,P4-bis(5'-adenosyl)-tetraphosphate adenylohydrolase; P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> ATP + AMP R00185 ATP:adenosine 5'-phosphotransferase; ATP + Adenosine <=> ADP + AMP R00187 P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase; P1,P3-Bis(5'-adenosyl) triphosphate + H2O <=> ADP + AMP R00188 adenosine-3',5'-bisphosphate 3'-phosphohydrolase; Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate R00189 deamido-NAD+:ammonia ligase (AMP-forming); ATP + Deamino-NAD+ + Ammonia <=> AMP + Diphosphate + NAD+ R00190 AMP:diphosphate phospho-D-ribosyltransferase; AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate R00191 adenosine 3',5'-phosphate 5'-nucleotidohydrolase; 3',5'-Cyclic AMP + H2O <=> AMP R00192 S-adenosyl-L-homocysteine hydrolase; S-Adenosyl-L-homocysteine + H2O <=> Adenosine + L-Homocysteine R00193 S-adenosyl-L-homocysteine aminohydrolase; S-Adenosyl-L-homocysteine + H2O <=> S-Inosyl-L-homocysteine + Ammonia R00194 S-adenosyl-L-homocysteine homocysteinylribohydrolase; S-Adenosyl-L-homocysteine + H2O <=> S-Ribosyl-L-homocysteine + Adenine R00195 2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming); 2,3-Diaminopropanoate + H2O <=> Pyruvate + 2 Ammonia R00196 (S)-lactate:ferricytochrome-c 2-oxidoreductase; (S)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+ R00197 (R)-lactate:ferricytochrome-c 2-oxidoreductase; (R)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+ R00198 (R)-lactate:ferricytochrome-c-553 2-oxidoreductase; (R)-Lactate + 2 Ferricytochrome c-553 <=> Pyruvate + 2 Ferrocytochrome c-553 + 2 H+ R00199 ATP:pyruvate,water phosphotransferase; ATP + Pyruvate + H2O <=> AMP + Phosphoenolpyruvate + Orthophosphate R00200 ATP:pyruvate 2-O-phosphotransferase; ATP + Pyruvate <=> ADP + Phosphoenolpyruvate R00203 pyruvaldehyde:NAD+ oxidoreductase; 2-oxopropanal:NAD+ oxidoreductase; Methylglyoxal + NAD+ + H2O <=> Pyruvate + NADH + H+ R00205 2-oxopropanal:NADP+ oxidoreductase; Methylglyoxal + NADP+ + H2O <=> Pyruvate + NADPH + H+ R00206 ATP:pyruvate,phosphate phosphotransferase; ATP + Pyruvate + Orthophosphate <=> AMP + Phosphoenolpyruvate + Diphosphate R00207 pyruvate:oxygen 2-oxidoreductase (phosphorylating); Pyruvate + Orthophosphate + Oxygen <=> Acetyl phosphate + Hydrogen peroxide + CO2 R00208 phosphoenolpyruvate phosphohydrolase; Phosphoenolpyruvate + H2O <=> Pyruvate + Orthophosphate R00209 pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex; Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+ R00210 pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating); Pyruvate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+ R00211 pyruvate:oxygen 2-oxidoreductase (CoA-acetylating); Pyruvate + CoA + Oxygen <=> Hydrogen peroxide + Acetyl-CoA + CO2 R00212 acetyl-CoA:formate C-acetyltransferase; Acetyl-CoA + Formate <=> CoA + Pyruvate R00213 O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming); O-Carbamoyl-L-serine + H2O <=> Pyruvate + 2 Ammonia + CO2 R00214 (S)-malate:NAD+ oxidoreductase (decarboxylating); (S)-Malate + NAD+ <=> Pyruvate + CO2 + NADH + H+ R00215 (R)-malate:NAD+ oxidoreductase (decarboxylating); (R)-Malate + NAD+ <=> Pyruvate + CO2 + NADH + H+ R00216 (S)-malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating); (S)-Malate + NADP+ <=> Pyruvate + CO2 + NADPH + H+ R00217 oxaloacetate carboxy-lyase (pyruvate-forming); Oxaloacetate <=> Pyruvate + CO2 R00218 acetylenedicarboxylate carboxy-lyase (pyruvate-forming); Acetylenedicarboxylate + H2O <=> Pyruvate + CO2 R00219 2-hydroxyethylenedicarboxylate carboxy-lyase (pyruvate-forming); Pyruvate + CO2 <=> 2-Hydroxyethylenedicarboxylate R00220 L-serine ammonia-lyase; L-Serine <=> Pyruvate + Ammonia R00221 D-serine ammonia-lyase; D-Serine <=> Pyruvate + Ammonia R00223 serine ammonia-lyase (pyruvate-forming); Serine <=> Pyruvate + Ammonia R00224 pyruvate carboxy-lyase (acetaldehyde-forming); Pyruvate <=> Acetaldehyde + CO2 R00226 pyruvate:pyruvate acetaldehydetransferase (decarboxylating); (S)-2-acetolactate pyruvate-lyase (carboxylating); (S)-2-Acetolactate + CO2 <=> 2 Pyruvate R00227 acetyl-CoA hydrolase; Acetyl-CoA + H2O <=> CoA + Acetate R00228 acetaldehyde:NAD+ oxidoreductase (CoA-acetylating); Acetaldehyde + CoA + NAD+ <=> Acetyl-CoA + NADH + H+ R00229 acetate:CoA ligase (ADP-forming); ATP + Acetate + CoA <=> ADP + Acetyl-CoA + Orthophosphate R00230 acetyl-CoA:phosphate acetyltransferase; Acetyl-CoA + Orthophosphate <=> CoA + Acetyl phosphate R00233 malonyl-CoA carboxy-lyase (acetyl-CoA-forming); Malonyl-CoA <=> Acetyl-CoA + CO2 R00235 acetate:CoA ligase (AMP-forming); ATP + Acetate + CoA <=> AMP + Diphosphate + Acetyl-CoA R00236 acetyl adenylate:CoA acetyltransferase; Acetyl adenylate + CoA <=> AMP + Acetyl-CoA R00237 (3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming); (3S)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate R00238 acetyl-CoA:acetyl-CoA C-acetyltransferase; 2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA R00239 ATP:L-glutamate 5-phosphotransferase; ATP + L-Glutamate <=> ADP + L-Glutamyl 5-phosphate R00243 L-glutamate:NAD+ oxidoreductase (deaminating); L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H+ R00245 L-glutamate gamma-semialdehyde:NAD+ oxidoreductase; L-Glutamate 5-semialdehyde + NAD+ + H2O <=> L-Glutamate + NADH + H+ R00248 L-glutamate:NADP+ oxidoreductase (deaminating); L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H+ R00250 L-glutamate:oxygen oxidoreductase (deaminating); L-Glutamate + Oxygen + H2O <=> 2-Oxoglutarate + Ammonia + Hydrogen peroxide R00251 5-oxo-L-proline amidohydrolase (ATP-hydrolysing); ATP + 5-Oxoproline + 2 H2O <=> ADP + Orthophosphate + L-Glutamate R00253 L-glutamate:ammonia ligase (ADP-forming); ATP + L-Glutamate + Ammonia <=> ADP + Orthophosphate + L-Glutamine R00254 N-carbamyl-L-glutamate amidohydrolase; L-Glutamate + Ammonia + CO2 <=> N-Carbamyl-L-glutamate + H2O R00256 L-glutamine amidohydrolase; L-Glutamine + H2O <=> L-Glutamate + Ammonia R00257 deamido-NAD+:L-glutamine amido-ligase (AMP-forming); ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate R00258 L-alanine:2-oxoglutarate aminotransferase; L-Alanine + 2-Oxoglutarate <=> Pyruvate + L-Glutamate R00259 acetyl-CoA:L-glutamate N-acetyltransferase; Acetyl-CoA + L-Glutamate <=> CoA + N-Acetyl-L-glutamate R00260 glutamate racemase; L-Glutamate <=> D-Glutamate R00261 L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming); L-Glutamate <=> 4-Aminobutanoate + CO2 R00262 L-threo-3-methylaspartate carboxy-aminomethylmutase; L-threo-3-Methylaspartate <=> L-Glutamate R00263 L-Glutamate <=> Poly-gamma-D-glutamate R00264 2,5-dioxopentanoate:NADP+ 5-oxidoreductase; 2,5-Dioxopentanoate + NADP+ + H2O <=> 2-Oxoglutarate + NADPH + H+ R00265 2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating); 2-Oxoglutarate + CoA + NADP+ <=> Succinyl-CoA + CO2 + NADPH + H+ R00267 isocitrate:NADP+ oxidoreductase (decarboxylating); Isocitrate + NADP+ <=> 2-Oxoglutarate + CO2 + NADPH + H+ R00268 oxalosuccinate carboxy-lyase (2-oxoglutarate-forming); Oxalosuccinate <=> 2-Oxoglutarate + CO2 R00269 2-oxoglutaramate amidohydrolase; 2-Oxoglutaramate + H2O <=> 2-Oxoglutarate + Ammonia R00270 2-Oxoglutarate + Ammonia <=> 4-Oxoglutaramate + H2O R00271 acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming); Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA R00272 2-oxoglutarate carboxy-lyase; 2-Oxoglutarate <=> Succinate semialdehyde + CO2 R00273 oxalate:oxygen oxidoreductase; Oxalate + Oxygen <=> Hydrogen peroxide + 2 CO2 R00274 glutathione:hydrogen-peroxide oxidoreductase; Hydrogen peroxide + 2 Glutathione <=> Glutathione disulfide + 2 H2O R00275 superoxide:superoxide oxidoreductase; 2 Superoxide + 2 H+ <=> Hydrogen peroxide + Oxygen R00277 pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating); Pyridoxamine phosphate + H2O + Oxygen <=> Pyridoxal phosphate + Ammonia + Hydrogen peroxide R00278 pyridoxine 5'-phosphate:oxygen oxidoreductase; Pyridoxine phosphate + Oxygen <=> Hydrogen peroxide + Pyridoxal phosphate R00279 D-glutamate:oxygen oxidoreductase (deaminating); D-Glutamate + H2O + Oxygen <=> 2-Oxoglutarate + Ammonia + Hydrogen peroxide R00280 nitric-oxide:acceptor oxidoreductase; Acceptor + 2 Nitric oxide + 2 H2O <=> Reduced acceptor + 2 Nitrite R00282 NADPH:acceptor oxidoreductase; Acceptor + NADPH + H+ <=> Reduced acceptor + NADP+ R00283 ammonium:acceptor oxidoreductase (ATP-forming); Acceptor + Ammonia + H2O + 2 Orthophosphate + 2 ADP <=> Hydroxylamine + Reduced acceptor + 2 ATP + 2 H2O R00284 ammonia:acceptor oxidoreductase; Acceptor + Ammonia + H2O <=> Hydroxylamine + Reduced acceptor R00286 UDP-glucose:NAD+ 6-oxidoreductase; UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + 2 H+ R00287 UDP-glucose glucophosphohydrolase; UDP-glucose + H2O <=> UMP + D-Glucose 1-phosphate R00289 UTP:alpha-D-glucose-1-phosphate uridylyltransferase; UTP + D-Glucose 1-phosphate <=> Diphosphate + UDP-glucose R00291 UDP-glucose 4-epimerase; UDP-alpha-D-glucose 4-epimerase; UDP-glucose <=> UDP-alpha-D-galactose R00292 UDP-glucose:glycogen 4-alpha-D-glucosyltransferase; UDP-glucose + Amylose <=> UDP + Amylose R00293 UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming); UDP-glucose <=> UDP-4-dehydro-6-deoxy-D-glucose + H2O R00294 nitrous-oxide:ferricytochrome-c oxidoreductase; 2 Nitric oxide + 2 Ferrocytochrome c + 2 H+ <=> Nitrous oxide + 2 Ferricytochrome c + H2O R00295 trithionate,NAD+ oxidoreductase; Trithionate + HO- + NAD+ + 2 H2O <=> 3 HSO3- + NADH + H+ R00297 (R)-2-hydroxy-acid:acceptor 2-oxidoreductase; (R)-Lactate + Acceptor <=> Pyruvate + Reduced acceptor R00298 (S)-2-hydroxyglutarate:acceptor 2-oxidoreductase; (S)-2-Hydroxyglutarate + Acceptor <=> 2-Oxoglutarate + Reduced acceptor R00299 ATP:D-glucose 6-phosphotransferase; ATP + D-Glucose <=> ADP + D-Glucose 6-phosphate R00300 D-glucose:NAD+ 1-oxidoreductase; D-Glucose + NAD+ <=> D-Glucono-1,5-lactone + NADH + H+ R00301 D-glucose:NADP+ 1-oxidoreductase; D-Glucose + NADP+ <=> D-Glucono-1,4-lactone + NADPH + H+ R00302 D-glucose:oxygen 2-oxidoreductase; D-Glucose + Oxygen <=> 2-Dehydro-D-glucose + Hydrogen peroxide R00303 D-glucose-6-phosphate phosphohydrolase; D-Glucose 6-phosphate + H2O <=> D-Glucose + Orthophosphate R00304 D-glucose-1-phosphate phosphohydrolase; D-Glucose 1-phosphate + H2O <=> D-Glucose + Orthophosphate R00305 D-glucose:quinone 1-oxidoreductase; D-Glucose + Quinone <=> D-Glucono-1,5-lactone + Hydroquinone R00306 cellobiose glucohydrolase; Cellobiose + H2O <=> 2 D-Glucose R00307 alpha-D-glucose aldose-ketose-isomerase; alpha-D-Glucose <=> alpha-D-Fructofuranose R00308 1,3-beta-D-glucan glucanohydrolase; 1,3-beta-D-Glucan + H2O <=> D-Glucose + 1,3-beta-D-Glucan R00310 protoheme ferro-lyase (protoporphyrin-forming); Protoporphyrin + Fe2+ <=> Heme + 2 H+ R00311 protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating); Heme + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Biliverdin + CO + Fe2+ + 3 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R00312 Heme <=> Cytochrome a R00313 Heme <=> Catalase R00314 Heme <=> Peroxidase R00315 ATP:acetate phosphotransferase; ATP + Acetate <=> ADP + Acetyl phosphate R00316 ATP:acetate adenylyltransferase; ATP + Acetate <=> Diphosphate + Acetyl adenylate R00317 acetyl phosphate phosphohydrolase; Acetyl phosphate + H2O <=> Acetate + Orthophosphate R00318 phosphonoacetate phosphonohydrolase; Phosphonoacetate + H2O <=> Acetate + Orthophosphate R00319 (S)-lactate:oxygen 2-oxidoreductase (decarboxylating); (S)-Lactate + Oxygen <=> Acetate + CO2 + H2O R00320 diphosphate:acetate phosphotransferase; Diphosphate + Acetate <=> Orthophosphate + Acetyl phosphate R00321 acetamide amidohydrolase; Acetamide + H2O <=> Acetate + Ammonia R00322 5'-acetylphosphoadenosine acetylhydrolase; Acetyl adenylate + H2O <=> AMP + Acetate R00324 2,4-dioxopentanoate acetylhydrolase; acetylpyruvate acetylhydrolase; Acetylpyruvate + H2O <=> Acetate + Pyruvate R00325 (2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase (acetate-forming); (3S)-citramalate pyruvate-lyase; (S)-2-Methylmalate <=> Acetate + Pyruvate R00326 acetaldehyde:acceptor oxidoreductase; Acetaldehyde + Acceptor + H2O <=> Acetate + Reduced acceptor R00327 6-acetyl-D-glucose acetylhydrolase; 6-Acetyl-D-glucose + H2O <=> D-Glucose + Acetate R00328 GDP phosphohydrolase; GDP + H2O <=> GMP + Orthophosphate R00329 nucleoside-diphosphate phosphohydrolase; NDP + H2O <=> Nucleotide + Orthophosphate R00330 ATP:GDP phosphotransferase; ATP + GDP <=> ADP + GTP R00331 ATP:nucleoside-diphosphate phosphotransferase; ATP + NDP <=> ADP + Nucleoside triphosphate R00332 ATP:GMP phosphotransferase; ATP + GMP <=> ADP + GDP R00333 nucleoside-triphosphate:AMP phosphotransferase; Nucleoside triphosphate + AMP <=> NDP + ADP R00334 ATP:nucleoside-phosphate phosphotransferase; ATP + Nucleoside phosphate <=> ADP + NDP R00335 GTP phosphohydrolase; GTP + H2O <=> GDP + Orthophosphate R00336 guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase; Guanosine 3',5'-bis(diphosphate) + H2O <=> GDP + Diphosphate R00337 GDP-glucose glucohydrolase; GDP-glucose + H2O <=> GDP + D-Glucose R00338 oxaloacetate acetylhydrolase; Oxaloacetate + H2O <=> Oxalate + Acetate R00339 (R,R)-tartrate hydro-lyase (oxaloacetate-forming); (R,R)-Tartaric acid <=> Oxaloacetate + H2O R00340 (S,S)-tartrate hydro-lyase (oxaloacetate-forming); (S,S)-Tartaric acid <=> Oxaloacetate + H2O R00341 ATP:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming); ATP + Oxaloacetate <=> ADP + Phosphoenolpyruvate + CO2 R00342 (S)-malate:NAD+ oxidoreductase; (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ R00343 (S)-malate:NADP+ oxidoreductase; (S)-Malate + NADP+ <=> Oxaloacetate + NADPH + H+ R00344 pyruvate:carbon-dioxide ligase (ADP-forming); ATP + Pyruvate + HCO3- <=> ADP + Orthophosphate + Oxaloacetate R00345 phosphate:oxaloacetate carboxy-lyase (adding phosphate;phosphoenolpyruvate-forming); Orthophosphate + Oxaloacetate <=> H2O + Phosphoenolpyruvate + CO2 R00346 diphosphate:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming); pyrophosphate:oxaloacetate carboxy-lyase (transphosphorylating); Diphosphate + Oxaloacetate <=> Orthophosphate + Phosphoenolpyruvate + CO2 R00347 erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming); erythro-3-Hydroxy-Ls-aspartate <=> Oxaloacetate + Ammonia R00348 2-oxosuccinamate amidohydrolase; 2-Oxosuccinamate + H2O <=> Oxaloacetate + Ammonia R00350 4-carboxy-4-hydroxy-2-oxoadipate oxaloacetate-lyase (pyruvate-forming); 4-Carboxy-4-hydroxy-2-oxoadipate <=> Oxaloacetate + Pyruvate R00351 acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing); Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate R00352 acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]; ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate R00353 malonyl-CoA:pyruvate carboxytransferase; Malonyl-CoA + Pyruvate <=> Acetyl-CoA + Oxaloacetate R00354 (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming); (3S)-Citryl-CoA <=> Acetyl-CoA + Oxaloacetate R00355 L-aspartate:2-oxoglutarate aminotransferase; L-Aspartate + 2-Oxoglutarate <=> Oxaloacetate + L-Glutamate R00357 L-aspartic acid:oxygen oxidoreductase (deaminating); L-Aspartate + H2O + Oxygen <=> Oxaloacetate + Ammonia + Hydrogen peroxide R00359 D-aspartate:oxygen oxidoreductase (deaminating); D-Aspartate + H2O + Oxygen <=> Oxaloacetate + Ammonia + Hydrogen peroxide R00360 (S)-malate:oxygen oxidoreductase; (S)-Malate + Oxygen <=> Oxaloacetate + Hydrogen peroxide R00361 (S)-malate:quinone oxidoreductase; (S)-Malate + Quinone <=> Oxaloacetate + Hydroquinone R00362 citrate oxaloacetate-lyase (forming acetate from the pro-S carboxymethyl group of citrate); citrate oxaloacetate-lyase ((pro-3S)-CH2COO- -->acetate); Citrate <=> Acetate + Oxaloacetate R00363 oxaloacetate keto-enol-isomerase; Oxaloacetate <=> 2-Hydroxyethylenedicarboxylate R00364 glycine:ferricytochrome-c oxidoreductase (deaminating); Glycine + H2O + 2 Ferricytochrome c <=> Glyoxylate + Ammonia + 2 Ferrocytochrome c + 2 H+ R00365 glycine:NAD+ oxidoreductase (deaminating); Glycine + H2O + NAD+ <=> Glyoxylate + Ammonia + NADH + H+ R00366 glycine:oxygen oxidoreductase (deaminating); aminoacetic acid:oxygen oxidoreductase (deaminating); Glycine + H2O + Oxygen <=> Glyoxylate + Ammonia + Hydrogen peroxide R00367 S-adenosyl-L-methionine:glycine N-methyltransferase; S-Adenosyl-L-methionine + Glycine <=> S-Adenosyl-L-homocysteine + Sarcosine R00368 N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming); N-(Carboxymethyl)-D-alanine + NAD+ + H2O <=> Glycine + Pyruvate + NADH + H+ R00369 L-alanine:glyoxylate aminotransferase; L-Alanine + Glyoxylate <=> Pyruvate + Glycine R00371 acetyl-CoA:glycine C-acetyltransferase; Acetyl-CoA + Glycine <=> CoA + L-2-Amino-3-oxobutanoic acid R00372 glycine:2-oxoglutarate aminotransferase; Glycine + 2-Oxoglutarate <=> Glyoxylate + L-Glutamate R00373 glycine:oxaloacetate aminotransferase; Glycine + Oxaloacetate <=> Glyoxylate + L-Aspartate R00374 glycine:acceptor oxidoreductase (cyanide-forming); Glycine + 2 Acceptor <=> Cyanide ion + CO2 + 2 Reduced acceptor + H+ R00375 deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dATP + DNA <=> Diphosphate + DNA R00376 deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dGTP + DNA <=> Diphosphate + DNA R00377 deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dCTP + DNA <=> Diphosphate + DNA R00378 deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dTTP + DNA <=> Diphosphate + DNA R00379 deoxynucleoside triphosphate:DNA deoxynucleotidyltransferase; Deoxynucleoside triphosphate + DNA(n) <=> Diphosphate + DNA(n+1) R00380 S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase; S-Adenosyl-L-methionine + DNA <=> S-Adenosyl-L-homocysteine + 5-Methylcytosine in DNA R00381 (deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming); ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m) R00382 (deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming); NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m) R00383 acyl-CoA hydrolase; Acyl-CoA + H2O <=> CoA + Carboxylate R00384 acyl-CoA:NAD+ trans-2-oxidoreductase; Acyl-CoA + NAD+ <=> trans-2,3-Dehydroacyl-CoA + NADH + H+ R00385 acyl-CoA:NADP+ 2-oxidoreductase; Acyl-CoA + NADP+ <=> 2,3-Dehydroacyl-CoA + NADPH + H+ R00387 acyl-CoA:NADP+ cis-2-oxidoreductase; Acyl-CoA + NADP+ <=> cis-2,3-Dehydroacyl-CoA + NADPH + H+ R00388 acyl-CoA:oxygen 2-oxidoreductase; Acyl-CoA + Oxygen <=> trans-2,3-Dehydroacyl-CoA + Hydrogen peroxide R00389 medium-chain-fatty-acid:CoA ligase (AMP-forming); ATP + Medium-chain fatty acid + CoA <=> AMP + Diphosphate + Medium-chain acyl-CoA R00390 long-chain-fatty-acid:CoA ligase (AMP-forming); ATP + Long-chain fatty acid + CoA <=> AMP + Diphosphate + Long-chain acyl-CoA R00391 acyl-CoA:acetyl-CoA C-acyltransferase; Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA R00392 acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Acyl-CoA + Electron-transferring flavoprotein <=> 2,3-Dehydroacyl-CoA + Reduced electron-transferring flavoprotein R00393 acyl-CoA:acetate CoA-transferase; Acyl-CoA + Acetate <=> Fatty acid anion + Acetyl-CoA R00394 carboxylic acid:CoA ligase (GDP-forming); GTP + Carboxylate + CoA <=> GDP + Orthophosphate + Acyl-CoA R00395 acyl-CoA:glycine N-acyltransferase; Acyl-CoA + Glycine <=> CoA + N-Acylglycine R00396 L-alanine:NAD+ oxidoreductase (deaminating); L-Alanine + NAD+ + H2O <=> Pyruvate + Ammonia + NADH + H+ R00397 L-aspartate 4-carboxy-lyase (L-alanine-forming); L-Aspartate <=> L-Alanine + CO2 R00398 2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming); Alanopine + NAD+ + H2O <=> L-Alanine + Pyruvate + NADH + H+ R00399 2-amino-4-ketopentanoate thiolase; acetyl-CoA:D-alanine C-acyltransferase; D-Alanine + Acetyl-CoA <=> 2-Amino-4-oxopentanoic acid + CoA R00400 L-alanine:oxaloacetate aminotransferase; L-Alanine + Oxaloacetate <=> Pyruvate + L-Aspartate R00401 alanine racemase; L-Alanine <=> D-Alanine R00402 succinate:NAD+ oxidoreductase; Succinate + NAD+ <=> Fumarate + NADH + H+ R00405 succinate:CoA ligase (ADP-forming); ATP + Succinate + CoA <=> ADP + Orthophosphate + Succinyl-CoA R00406 succinyl-CoA:(S)-malate CoA-transferase; Succinyl-CoA + (S)-Malate <=> Succinate + L-Malyl-CoA R00407 succinyl-CoA hydrolase; Succinyl-CoA + H2O <=> CoA + Succinate R00408 succinate:FAD oxidoreductase; Succinate + FAD <=> FADH2 + Fumarate R00409 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming); (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate <=> Pyruvate + Succinate R00410 succinyl-CoA:acetoacetate CoA-transferase; Succinyl-CoA + Acetoacetate <=> Succinate + Acetoacetyl-CoA R00411 N-succinyl-L-glutamate amidohydrolase; N-Succinyl-L-glutamate + H2O <=> L-Glutamate + Succinate R00412 succinate:acceptor oxidoreductase; Succinate + Acceptor <=> Fumarate + Reduced acceptor R00414 UDP-N-acetyl-D-glucosamine 2-epimerase; UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP R00416 UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase; UTP + N-Acetyl-alpha-D-glucosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-alpha-D-glucosamine R00417 UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Protein asparagine <=> UDP + 4-N-(N-Acetyl-D-glucosaminyl)-protein R00418 UDP-N-acetyl-D-glucosamine 4-epimerase; UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-D-galactosamine R00420 UDP-N-acetyl-D-glucosamine 2-epimerase; UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-D-mannosamine R00421 UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+ R00422 UDP-N-acetyl-alpha-D-glucosamine <=> Glycolipid R00423 UDP-N-acetyl-alpha-D-glucosamine <=> Mucopolysaccharide R00424 GTP 7,8-8,9-dihydrolase; GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate R00425 GTP 7,8-8,9-dihydrolase (diphosphate-forming); GTP + 4 H2O <=> Formate + 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 Orthophosphate R00426 GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase; GTP + H2O <=> GMP + Diphosphate R00428 GTP 8,9-hydrolase; GTP + H2O <=> Formamidopyrimidine nucleoside triphosphate R00429 ATP:GTP 3'-diphosphotransferase; ATP + GTP <=> AMP + Guanosine 3'-diphosphate 5'-triphosphate R00430 GTP:pyruvate 2-O-phosphotransferase; GTP + Pyruvate <=> GDP + Phosphoenolpyruvate R00431 GTP:oxaloacetate carboxy-lyase (adding GTP;phosphoenolpyruvate-forming); GTP:oxaloacetate carboxy-lyase (transphosphorylating); GTP + Oxaloacetate <=> GDP + Phosphoenolpyruvate + CO2 R00432 succinate:CoA ligase (GDP-forming); GTP + Succinate + CoA <=> GDP + Orthophosphate + Succinyl-CoA R00434 GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming); GTP <=> 3',5'-Cyclic GMP + Diphosphate R00435 ATP:polynucleotide adenylyltransferase; ATP:RNA adenylyltransferase; ATP + RNA <=> Diphosphate + RNA R00436 polyribonucleotide ligase (cyclizing, AMP-forming); ATP + RNA <=> AMP + Diphosphate + RNA(circular) R00437 polyribonucleotide:phosphate adenylyltransferase; RNA + Orthophosphate <=> RNA + ADP R00438 polyribonucleotide:phosphate uridylyltransferase; RNA + Orthophosphate <=> RNA + UDP R00439 polyribonucleotide:phosphate guanylyltransferase; RNA + Orthophosphate <=> RNA + GDP R00440 polyribonucleotide:phosphate cytidylyltransferase; RNA + Orthophosphate <=> RNA + CDP R00441 GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA guanylyltransferase (RNA-directed); GTP + RNA <=> Diphosphate + RNA R00442 CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA cytidylyltransferase (RNA-directed); CTP + RNA <=> Diphosphate + RNA R00443 UTP:RNA uridylyltransferase; UTP + RNA <=> Diphosphate + RNA R00444 nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed); nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed); Nucleoside triphosphate + RNA <=> Diphosphate + RNA R00445 L-lysine:NAD+ oxidoreductase (deaminating, cyclizing); L-Lysine + NAD+ <=> Delta1-Piperideine-2-carboxylate + Ammonia + NADH + H+ R00446 L-lysine:NAD+ 6-oxidoreductase (deaminating); L-Lysine + NAD+ + H2O <=> L-2-Aminoadipate 6-semialdehyde + NADH + Ammonia + H+ R00447 L-lysine:oxygen 2-oxidoreductase (deaminating); L-Lysine + Oxygen + H2O <=> 6-Amino-2-oxohexanoate + Ammonia + Hydrogen peroxide R00448 L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating); L-Lysine + Oxygen + NADPH + H+ <=> N6-Hydroxy-L-lysine + NADP+ + H2O R00449 L-lysine:oxygen 2-oxidoreductase (decarboxylating); L-Lysine + Oxygen <=> 5-Aminopentanamide + CO2 + H2O R00451 meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming); meso-2,6-Diaminoheptanedioate <=> L-Lysine + CO2 R00452 N2-(D-1-carboxylethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming); D-Lysopine + NADP+ + H2O <=> L-Lysine + Pyruvate + NADPH + H+ R00453 L-lysine:pyruvate aminotransferase; L-Lysine + Pyruvate <=> L-2-Aminoadipate 6-semialdehyde + L-Alanine R00454 acetyl-CoA:L-lysine N6-acetyltransferase; L-Lysine + Acetyl-CoA <=> N6-Acetyl-L-lysine + CoA R00457 L-lysine:2-oxoglutarate 6-aminotransferase; L-Lysine + 2-Oxoglutarate <=> L-2-Aminoadipate 6-semialdehyde + L-Glutamate R00458 N6-acetyl-L-lysine amidohydrolase; N6-Acetyl-L-lysine + H2O <=> Acetate + L-Lysine R00459 L-Lysine <=> L-Pipecolate R00460 lysine racemase; L-Lysine <=> D-Lysine R00461 L-lysine 2,3-aminomutase; L-Lysine <=> (3S)-3,6-Diaminohexanoate R00462 L-lysine carboxy-lyase (cadaverine-forming); L-Lysine <=> Cadaverine + CO2 R00463 L-lysine-1,6-lactam lactamhydrolase; L-Lysine 1,6-lactam + H2O <=> L-Lysine R00465 glycolate:NADP+ oxidoreductase; Glycolate + NADP+ <=> Glyoxylate + NADPH + H+ R00466 glyoxylate:oxygen oxidoreductase; Glyoxylate + Oxygen + H2O <=> Oxalate + Hydrogen peroxide R00468 glyoxylate:NADP+ oxidoreductase (CoA-oxalylating); Glyoxylate + CoA + NADP+ <=> Oxalyl-CoA + NADPH + H+ R00469 (S)-ureidoglycolate amidohydrolase (decarboxylating); (S)-Ureidoglycolate + H2O <=> Glyoxylate + 2 Ammonia + CO2 R00470 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming); 4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate R00471 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming); (4R)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate R00472 acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); L-malate glyoxylate-lyase (CoA-acetylating); (S)-Malate + CoA <=> Acetyl-CoA + H2O + Glyoxylate R00473 L-malyl-CoA glyoxylate-lyase (acetyl-CoA-forming); L-Malyl-CoA <=> Acetyl-CoA + Glyoxylate R00474 2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating); 2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating); 2-Hydroxy-3-oxoadipate + CO2 <=> 2-Oxoglutarate + Glyoxylate R00475 glycolate:oxygen 2-oxidoreductase; Glycolate + Oxygen <=> Glyoxylate + Hydrogen peroxide R00476 glycolate:acceptor 2-oxidoreductase; Glycolate + Acceptor <=> Glyoxylate + Reduced acceptor R00477 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming); 3-Oxalomalate <=> Oxaloacetate + Glyoxylate R00478 erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming); erythro-3-Hydroxy-Ls-aspartate <=> Glycine + Glyoxylate R00479 isocitrate glyoxylate-lyase (succinate-forming); Isocitrate <=> Succinate + Glyoxylate R00480 ATP:L-aspartate 4-phosphotransferase; ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate R00481 L-aspartate:oxygen oxidoreductase; L-Aspartate + Oxygen <=> Iminoaspartate + Hydrogen peroxide R00482 L-aspartate:ammonia ligase (ADP-forming); ATP + L-Aspartate + Ammonia <=> ADP + Orthophosphate + L-Asparagine R00483 L-aspartate:ammonia ligase (AMP-forming); ATP + L-Aspartate + Ammonia <=> AMP + Diphosphate + L-Asparagine R00484 N-carbamoyl-L-aspartate amidohydrolase; N-Carbamoyl-L-aspartate + H2O <=> L-Aspartate + CO2 + Ammonia R00485 L-asparagine amidohydrolase; L-Asparagine + H2O <=> L-Aspartate + Ammonia R00486 3-cyano-L-alanine aminohydrolase; 3-Cyano-L-alanine + 2 H2O <=> L-Aspartate + Ammonia R00487 acetyl-CoA:L-aspartate N-acetyltransferase; Acetyl-CoA + L-Aspartate <=> CoA + N-Acetyl-L-aspartate R00488 N-acetyl-L-aspartate amidohydrolase; N-Acetyl-L-aspartate + H2O <=> Acetate + L-Aspartate R00489 L-aspartate 1-carboxy-lyase (beta-alanine-forming); L-Aspartate <=> beta-Alanine + CO2 R00490 L-aspartate ammonia-lyase (fumarate-forming); L-Aspartate <=> Fumarate + Ammonia R00491 aspartate racemase; L-Aspartate <=> D-Aspartate R00493 L-aspartate:2-oxo acid aminotransferase; L-Aspartate + 2-Oxo acid <=> alpha-Amino acid + Oxaloacetate R00494 glutathione gamma-glutamylaminopeptidase; Glutathione + H2O <=> Cys-Gly + L-Glutamate R00497 gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming); ATP + gamma-L-Glutamyl-L-cysteine + Glycine <=> ADP + Orthophosphate + Glutathione R00499 S-succinylglutathione hydrolase; S-Succinylglutathione + H2O <=> Glutathione + Succinate R00501 UDP-alpha-D-galactose:NAD+ 6-oxidoreductase; UDP-alpha-D-galactose + 2 NAD+ + H2O <=> UDP-D-galacturonate + 2 NADH + 2 H+ R00502 UTP:alpha-D-galactose-1-phosphate uridylyltransferase; UTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + UDP-alpha-D-galactose R00503 UDP-alpha-D-galactose:D-glucose 4-beta-D-galactosyltransferase; UDP-alpha-D-galactose + D-Glucose <=> UDP + Lactose R00504 UDP-alpha-D-galactose:UDP-N-acetyl-alpha-D-glucosamine galactose phosphotransferase; UDP-alpha-D-galactose + UDP-N-acetyl-alpha-D-glucosamine <=> UMP + UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine R00505 UDP-alpha-D-galactopyranose furanomutase; UDP-alpha-D-galactose <=> UDP-alpha-D-galactofuranose R00506 UDP-alpha-D-galactose:galactan beta-1,4-D-galactosyltransferase; UDP-alpha-D-galactose + Galactan <=> Galactan + UDP R00507 3'-phosphoadenylyl-sulfate sulfohydrolase; 3'-phosphoadenylyl-sulfate nucleotidohydrolase; 3'-Phosphoadenylyl sulfate + H2O <=> Sulfate + Adenosine 3',5'-bisphosphate R00508 3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase; 3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate R00509 ATP:adenylylsulfate 3'-phosphotransferase; ATP + Adenylyl sulfate <=> ADP + 3'-Phosphoadenylyl sulfate R00510 cytidine-5'-monophosphate phosphoribohydrolase; CMP + H2O <=> Cytosine + D-Ribose 5-phosphate R00511 cytidine-5'-monophosphate phosphohydrolase; CMP + H2O <=> Cytidine + Orthophosphate R00512 ATP:CMP phosphotransferase; ATP + CMP <=> ADP + CDP R00513 ATP:cytidine 5'-phosphotransferase; ATP + Cytidine <=> ADP + CMP R00514 CDP phosphohydrolase; CDP + H2O <=> CMP + Orthophosphate R00515 CTP diphosphohydrolase (diphosphate-forming); CTP pyrophosphohydrolase; CTP + H2O <=> CMP + Diphosphate R00517 GTP:cytidine 5'-phosphotransferase; GTP + Cytidine <=> GDP + CMP R00518 ATP:formate phosphotransferase; ATP + Formate <=> ADP + Formyl phosphate R00519 formate:NAD+ oxidoreductase; Formate + NAD+ <=> H+ + CO2 + NADH R00521 formyl-CoA hydrolase; Formyl-CoA + H2O <=> CoA + Formate R00522 oxalate carboxy-lyase; Oxalate <=> Formate + CO2 R00524 formamide amidohydrolase; Formamide + H2O <=> Formate + Ammonia R00525 N-formyl-L-glutamate amidohydrolase; N-Formyl-L-glutamate + H2O <=> Formate + L-Glutamate R00526 N-formyl-L-aspartate amidohydrolase; N-Formyl-L-aspartate + H2O <=> Formate + L-Aspartate R00527 S-formylglutathione hydrolase; S-Formylglutathione + H2O <=> Formate + Glutathione R00528 sulfite:ferricytochrome-c oxidoreductase; Sulfite + H2O + 2 Ferricytochrome c <=> Sulfate + 2 Ferrocytochrome c + 2 H+ R00529 ATP:sulfate adenylyltransferase; ATP + Sulfate <=> Diphosphate + Adenylyl sulfate R00530 ADP:sulfate adenylyltransferase; ADP + Sulfate <=> Orthophosphate + Adenylyl sulfate R00531 adenylylsulfate sulfohydrolase; Adenylyl sulfate + H2O <=> AMP + Sulfate R00532 L-serine-O-sulfate ammonia-lyase (pyruvate-forming); L-Serine O-sulfate + H2O <=> Pyruvate + Ammonia + Sulfate R00533 sulfite:oxygen oxidoreductase; Sulfite + Oxygen + H2O <=> Sulfate + Hydrogen peroxide R00534 D-glucose 6-sulfate sulfohydrolase; D-Glucose 6-sulfate + H2O <=> D-Glucose + Sulfate R00535 3'-phosphoadenylylsulfate:17beta-estradiol 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Estradiol-17beta <=> Adenosine 3',5'-bisphosphate + Estradiol-17beta 3-sulfate R00536 3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + 2-Methoxyestrone <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestrone 3-sulfate R00537 3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + 2-Methoxy-17beta-estradiol <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestradiol-17beta 3-sulfate R00538 aldehyde:NAD+ oxidoreductase; Aldehyde + NAD+ + H2O <=> Carboxylate + NADH + H+ R00539 acyl phosphate phosphohydrolase; Acyl phosphate + H2O <=> Carboxylate + Orthophosphate R00540 nitrile aminohydrolase; Nitrile + 2 H2O <=> Carboxylate + Ammonia R00542 5'-acylphosphoadenosine acylhydrolase; 5'-Acylphosphoadenosine + H2O <=> AMP + Carboxylate R00543 3-acylpyruvate acylhydrolase; 3-Acylpyruvate + H2O <=> Carboxylate + Pyruvate R00544 aldehyde:acceptor oxidoreductase; Aldehyde + Acceptor + H2O <=> Carboxylate + Reduced acceptor R00545 N6-acyl-L-lysine amidohydrolase; N6-Acyl-L-lysine + H2O <=> Carboxylate + L-Lysine R00546 N-acyl-L-aspartate amidohydrolase; N-Acyl-L-aspartate + H2O <=> Carboxylate + L-Aspartate R00547 S-acylglutathione hydrolase; S-Acylglutathione + H2O <=> Carboxylate + Glutathione R00548 riboflavin-5-phosphate phosphohydrolase; FMN + H2O <=> Riboflavin + Orthophosphate R00549 ATP:riboflavin 5'-phosphotransferase; ATP + Riboflavin <=> ADP + FMN R00550 D-glucose-1-phosphate:riboflavin 5'-phosphotransferase; D-Glucose 1-phosphate + Riboflavin <=> D-Glucose + FMN R00551 L-arginine amidinohydrolase; L-Arginine + H2O <=> L-Ornithine + Urea R00552 L-arginine iminohydrolase; L-Arginine + H2O <=> L-Citrulline + Ammonia R00554 ATP:L-arginine Nomega-phosphotransferase; ATP + L-Arginine <=> ADP + L-Arginine phosphate R00555 NAD+:protein-L-arginine ADP-D-ribosyltransferase; NAD+ + Protein-L-arginine <=> Nicotinamide + Protein-omega-N-(ADP-D-ribosyl)-L-arginine R00557 L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming); 2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2O R00558 L-arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming); L-Arginine + Oxygen + NADPH + H+ <=> N(omega)-Hydroxyarginine + NADP+ + H2O R00559 L-arginine:oxygen 2-oxidoreductase (decarboxylating); L-Arginine + Oxygen <=> 4-Guanidinobutanamide + CO2 + H2O R00562 N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming); Octopine + NAD+ + H2O <=> L-Arginine + Pyruvate + NADH + H+ R00563 N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming); D-nopaline:NADP+ oxidoreductase (L-arginine-forming); Nopaline + NADP+ + H2O <=> L-Arginine + 2-Oxoglutarate + NADPH + H+ R00565 L-arginine:glycine amidinotransferase; L-Arginine + Glycine <=> L-Ornithine + Guanidinoacetate R00566 L-arginine carboxy-lyase (agmatine-forming); L-Arginine <=> Agmatine + CO2 R00567 arginine racemase; L-Arginine <=> D-Arginine R00569 CTP phosphohydrolase; CTP + H2O <=> CDP + Orthophosphate R00570 ATP:CDP phosphotransferase; ATP + CDP <=> ADP + CTP R00571 UTP:ammonia ligase (ADP-forming); ATP + UTP + Ammonia <=> ADP + Orthophosphate + CTP R00572 CTP:pyruvate 2-O-phosphotransferase; CTP + Pyruvate <=> CDP + Phosphoenolpyruvate R00573 UTP:L-glutamine amido-ligase (ADP-forming); ATP + UTP + L-Glutamine + H2O <=> ADP + Orthophosphate + CTP + L-Glutamate R00574 CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming); CTP <=> 3',5'-Cyclic CMP + Diphosphate R00575 HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating); 2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate R00576 L-glutamine:pyruvate aminotransferase; L-Glutamine + Pyruvate <=> 2-Oxoglutaramate + L-Alanine R00577 acyl-CoA:L-glutamine N-acyltransferase; Acyl-CoA + L-Glutamine <=> CoA + N-Acyl-L-glutamine R00578 L-aspartate:L-glutamine amido-ligase (AMP-forming); ATP + L-Aspartate + L-Glutamine + H2O <=> AMP + Diphosphate + L-Asparagine + L-Glutamate R00579 glutamine racemase; L-Glutamine <=> D-Glutamine R00581 L-serine:NAD+ oxidoreductase (deaminating); L-Serine + NAD+ + H2O <=> Hydroxypyruvate + Ammonia + NADH + H+ R00582 O-phospho-L-serine phosphohydrolase; O-Phospho-L-serine + H2O <=> L-Serine + Orthophosphate R00584 diphosphate:L-serine O-phosphotransferase; Diphosphate + L-Serine <=> Orthophosphate + O-Phospho-L-serine R00585 L-serine:pyruvate aminotransferase; L-Serine + Pyruvate <=> Hydroxypyruvate + L-Alanine R00586 acetyl-CoA:L-serine O-acetyltransferase; L-Serine + Acetyl-CoA <=> O-Acetyl-L-serine + CoA R00588 L-serine:glyoxylate aminotransferase; L-Serine + Glyoxylate <=> Hydroxypyruvate + Glycine R00589 serine racemase; L-Serine <=> D-Serine R00590 L-serine hydro-lyase; L-Serine <=> Dehydroalanine + H2O R00594 S-adenosyl-L-methionine:tRNA uracil 5-methyltransferase; S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase; S-Adenosyl-L-methionine + tRNA containing uridine at position 54 <=> S-Adenosyl-L-homocysteine + tRNA containing ribothymidine at position 54 R00595 S-adenosyl-L-methionine:tRNA (cytosine-C5)-methyltransferase; S-Adenosyl-L-methionine + tRNA cytosine <=> S-Adenosyl-L-homocysteine + tRNA containing 5-methylcytosine R00596 S-adenosyl-L-methionine:tRNA adenine N1-methyltransferase; S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase; S-Adenosyl-L-methionine + tRNA adenine <=> S-Adenosyl-L-homocysteine + tRNA containing N1-methyladenine R00597 S-adenosyl-L-methionine:tRNA guanine N1-methyltransferase; S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase; S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N1-methylguanine R00598 S-adenosyl-L-methionine:tRNA guanine N2-methyltransferase; S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase; S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N2-methylguanine R00599 S-adenosyl-L-methionine:tRNA adenine N6-methyltransferase; S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase; S-Adenosyl-L-methionine + tRNA adenine <=> S-Adenosyl-L-homocysteine + tRNA containing N6-methyladenine R00600 S-adenosyl-L-methionine:tRNA guanine N7-methyltransferase; S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase; S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing N7-methylguanine R00601 S-adenosyl-L-methionine:tRNA 5-methylaminomethyl-2-thiouridine methyltransferase; S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; S-Adenosyl-L-methionine + tRNA containing 5-(aminomethyl)-2-thiouridine <=> S-Adenosyl-L-homocysteine + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate R00602 methanol:hydrogen-peroxide oxidoreductase; Methanol + Hydrogen peroxide <=> Formaldehyde + 2 H2O R00603 dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming); Dichloromethane + H2O <=> Formaldehyde + 2 Hydrochloric acid R00604 formaldehyde:NAD+ oxidoreductase; Formaldehyde + NAD+ + H2O <=> Formate + NADH + H+ R00605 methanol:NAD+ oxidoreductase; Methanol + NAD+ <=> Formaldehyde + NADH + H+ R00606 methylamine:amicyanin oxidoreductase (deaminating); Methylamine + H2O + 2 Amicyanin <=> Formaldehyde + Ammonia + 2 Reduced amicyanin + 2 H+ R00608 methanol:oxygen oxidereductase; Methanol + Oxygen <=> Formaldehyde + Hydrogen peroxide R00609 N-methyl-L-glutamate:acceptor oxidoreductase (demethylating); N-Methyl-L-glutamate + Acceptor + H2O <=> L-Glutamate + Formaldehyde + Reduced acceptor R00610 sarcosine:oxygen oxidoreductase (demethylating); Sarcosine + H2O + Oxygen <=> Glycine + Formaldehyde + Hydrogen peroxide R00611 sarcosine:electron-transfer flavoprotein oxidoreductase (demethylating); Sarcosine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Glycine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein R00612 N6-methyl-L-lysine:oxygen oxidoreductase (demethylating); N6-Methyl-L-lysine + H2O + Oxygen <=> L-Lysine + Formaldehyde + Hydrogen peroxide R00614 formaldehyde:formaldehyde oxidoreductase; 2 Formaldehyde + H2O <=> Formate + Methanol R00615 thiamin diphosphate phosphohydrolase; Thiamin diphosphate + H2O <=> Thiamin monophosphate + Orthophosphate R00616 ATP:thiamine-diphosphate phosphotransferase; ATP + Thiamin diphosphate <=> ADP + Thiamin triphosphate R00617 ATP:thiamin-phosphate phosphotransferase; ATP + Thiamin monophosphate <=> ADP + Thiamin diphosphate R00618 thiamin-triphosphate phosphohydrolase; Thiamin triphosphate + H2O <=> Thiamin diphosphate + Orthophosphate R00619 ATP:thiamine diphosphotransferase; ATP + Thiamine <=> AMP + Thiamin diphosphate R00621 2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2 R00623 primary_alcohol:NAD+ oxidoreductase; Primary alcohol + NAD+ <=> Aldehyde + NADH + H+ R00624 secondary_alcohol:NAD+ oxidoreductase; Secondary alcohol + NAD+ <=> Ketone + NADH + H+ R00625 primary_alcohol:NADP+ oxidoreductase; Primary alcohol + NADP+ <=> Aldehyde + NADPH + H+ R00626 phosphate-monoester phosphohydrolase; Orthophosphoric monoester + H2O <=> Alcohol + Orthophosphate R00627 acetyl-CoA:alcohol O-acetyltransferase; Acetyl-CoA + Alcohol <=> CoA + Acetic ester R00628 acetic-ester acetylhydrolase; Acetic ester + H2O <=> Alcohol + Acetate R00629 3'-phosphoadenylyl-sulfate:alcohol sulfotransferase; Alcohol + 3'-Phosphoadenylyl sulfate <=> Alkyl sulfate + Adenosine 3',5'-bisphosphate R00630 carboxylic-ester hydrolase; Ester + H2O <=> Alcohol + Carboxylate R00631 aldehyde:NAD+ oxidoreductase; Aldehyde + NAD+ + H2O <=> Fatty acid + NADH + H+ R00634 aldehyde:NADP+ oxidoreductase; Aldehyde + NADP+ + H2O <=> Carboxylate + NADPH + H+ R00635 aldehyde:oxygen oxidoreductase; Aldehyde + Oxygen + H2O <=> Carboxylate + Hydrogen peroxide R00636 2-oxo-acid carboxy-lyase (aldehyde-forming); 2-Oxo acid <=> Aldehyde + CO2 R00637 primary alcohol:oxygen oxidoreductase; Primary alcohol + Oxygen <=> Aldehyde + Hydrogen peroxide R00638 aldehyde:acceptor oxidoreductase; Aldehyde + Acceptor + H2O <=> Fatty acid + Reduced acceptor R00639 primary alcohol:acceptor oxidoreductase; Primary alcohol + Acceptor <=> Aldehyde + Reduced acceptor R00640 L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase; L-Galactono-1,4-lactone + 2 Ferricytochrome c <=> Ascorbate + 2 Ferrocytochrome c + 2 H+ R00643 L-galactono-1,4-lactone:oxygen 3-oxidoreductase; L-Galactono-1,4-lactone + Oxygen <=> Ascorbate + Hydrogen peroxide R00644 L-ascorbate:hydrogen-peroxide oxidoreductase; Ascorbate + Hydrogen peroxide <=> Dehydroascorbate + 2 H2O R00645 ascorbate:acceptor oxidoreductase; 2 Ascorbate + Acceptor <=> 2 Monodehydroascorbate + Reduced acceptor R00646 Ascorbate + Oxygen + H2O <=> Threonate + Oxalate R00647 Ascorbate <=> L-xylo-Hexulonolactone R00648 L-methionine:oxygen oxidoreductase (deaminating); L-Methionine + H2O + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Ammonia + Hydrogen peroxide R00649 S-adenosyl-L-methionine:L-methionine S-methyltransferase; S-Adenosyl-L-methionine + L-Methionine <=> S-Adenosyl-L-homocysteine + S-Methyl-L-methionine R00650 S-adenosyl-L-methionine:L-homocysteine S-methyltransferase; S-Adenosyl-L-methionine + L-Homocysteine <=> S-Adenosyl-L-homocysteine + L-Methionine R00651 O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase; O-acetyl-L-homoserine acetate-lyase (adding methanethiol); O-Acetyl-L-homoserine + Methanethiol <=> L-Methionine + Acetate R00652 L-methionine:glyoxylate aminotransferase; L-Methionine + Glyoxylate <=> 4-Methylthio-2-oxobutanoic acid + Glycine R00653 N-formyl-L-methionine amidohydrolase; N-Formylmethionine + H2O <=> Formate + L-Methionine R00654 L-methionine methanethiol-lyase (deaminating;2-oxobutanoate-forming); L-Methionine + H2O <=> Methanethiol + Ammonia + 2-Oxobutanoate R00655 methionine racemase; L-Methionine <=> D-Methionine R00656 L-methionine carboxy-lyase (3-methylthiopropanamine-forming); L-Methionine <=> 3-Methylthiopropanamine + CO2 R00657 Aminoacyl-L-methionine + H2O <=> L-Methionine R00658 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming); 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O R00659 UTP:pyruvate 2-O-phosphotransferase; UTP + Pyruvate <=> UDP + Phosphoenolpyruvate R00660 phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyl-transferase; Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + Orthophosphate R00661 phosphoenolpyruvate 2,3-phosphonomutase; Phosphoenolpyruvate <=> 3-Phosphonopyruvate R00662 uridine triphosphate pyrophosphohydrolase; UTP + H2O <=> UMP + Diphosphate R00664 bezoyl-CoA:L-ornithine N-benzoyltransferase; 2 Benzoyl-CoA + L-Ornithine <=> 2 CoA + N2,N5-Dibenzoyl-L-ornithine R00665 L-citrulline N5-carbamoyldihydrolase; L-Citrulline + H2O <=> L-Ornithine + CO2 + Ammonia R00666 N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming); N5-(L-1-Carboxyethyl)-L-ornithine + NADP+ + H2O <=> L-Ornithine + Pyruvate + NADPH + H+ R00667 L-ornithine:2-oxo-acid aminotransferase; L-Ornithine + 2-Oxoglutarate <=> L-Glutamate 5-semialdehyde + L-Glutamate R00668 L-ornithine:2-oxoglutarate aminotransferase; L-Ornithine + 2-Oxoglutarate <=> Delta1-Pyrroline-5-carboxylate + L-Glutamate + H2O R00669 N2-acetyl-L-ornithine amidohydrolase; N-Acetylornithine + H2O <=> Acetate + L-Ornithine R00670 L-ornithine carboxy-lyase (putrescine-forming); L-Ornithine <=> Putrescine + CO2 R00671 L-ornithine ammonia-lyase (cyclizing; L-proline-forming); L-Ornithine <=> L-Proline + Ammonia R00672 ornithine racemase; L-Ornithine <=> D-Ornithine R00673 L-tryptophan indole-lyase (deaminating; pyruvate-forming); L-Tryptophan + H2O <=> Indole + Pyruvate + Ammonia R00674 L-serine hydro-lyase (adding indole; L-tryptophan-forming); L-Serine + Indole <=> L-Tryptophan + H2O R00675 L-tryptophan:NAD+ oxidoreductase (deaminating); L-Tryptophan + NAD+ + H2O <=> Indolepyruvate + Ammonia + NADH + H+ R00676 L-tryptophan:NADP+ oxidoreductase (deaminating); L-Tryptophan + NADP+ + H2O <=> Indolepyruvate + Ammonia + NADPH + H+ R00677 L-tryptophan:oxygen oxidoreductase (deaminating); L-Tryptophan + H2O + Oxygen <=> Indolepyruvate + Ammonia + Hydrogen peroxide R00678 L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing); L-Tryptophan + Oxygen <=> L-Formylkynurenine R00679 L-tryptophan:oxygen 2-oxidoreductase (decarboxylating); L-Tryptophan + Oxygen <=> (Indol-3-yl)acetamide + CO2 + H2O R00681 L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving); L-Tryptophan + Oxygen <=> (Indol-3-yl)glycolaldehyde + Ammonia + CO2 R00682 L-tryptophanamide amidohydrolase; L-Tryptophanamide + H2O <=> L-Tryptophan + Ammonia R00683 S-adenosyl-L-methionine:L-tryptophan N-methyltransferase; S-Adenosyl-L-methionine + L-Tryptophan <=> S-Adenosyl-L-homocysteine + Abrine R00684 L-tryptophan:2-oxoglutarate aminotransferase; L-Tryptophan + 2-Oxoglutarate <=> Indolepyruvate + L-Glutamate R00685 L-tryptophan decarboxy-lyase; L-Tryptophan <=> Tryptamine + CO2 R00686 L-phenylalanine racemase (ATP-hydrolysing); ATP + L-Phenylalanine + H2O <=> AMP + Diphosphate + D-Phenylalanine R00688 L-phenylalanine:NAD+ oxidoreductase (deaminating); L-Phenylalanine + H2O + NAD+ <=> Phenylpyruvate + Ammonia + NADH + H+ R00689 L-phenylalanine:oxygen oxidoreductase (deaminating); L-Phenylalanine + H2O + Oxygen <=> Phenylpyruvate + Ammonia + Hydrogen peroxide R00690 L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating); L-Phenylalanine + Oxygen <=> 2-Phenylacetamide + CO2 + H2O R00691 L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming); L-Arogenate <=> L-Phenylalanine + H2O + CO2 R00692 L-phenylalanine:pyruvate aminotransferase; L-Phenylalanine + Pyruvate <=> Phenylpyruvate + L-Alanine R00693 acetyl-CoA:L-phenylalanine N-acetyltransferase; Acetyl-CoA + L-Phenylalanine <=> CoA + N-Acetyl-L-phenylalanine R00694 L-phenylalanine:2-oxoglutarate aminotransferase; L-Phenylalanine + 2-Oxoglutarate <=> Phenylpyruvate + L-Glutamate R00695 L-aspartate:phenylpyruvate aminotransferase; L-Aspartate + Phenylpyruvate <=> Oxaloacetate + L-Phenylalanine R00697 L-phenylalanine ammonia-lyase (trans-cinnamate-forming); L-Phenylalanine <=> trans-Cinnamate + Ammonia R00698 L-phenylalanine:oxygen oxidoreductase (decarboxylating); L-Phenylalanine + Oxygen <=> 2-Phenylacetamide + CO2 R00699 L-phenylalanine carboxy-lyase (phenylethylamine-forming); L-Phenylalanine <=> Phenethylamine + CO2 R00700 hydrogen:NAD+ oxidoreductase; Hydrogen + NAD+ <=> NADH + H+ R00702 farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase; 2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate R00703 (S)-lactate:NAD+ oxidoreductase; (S)-Lactate + NAD+ <=> Pyruvate + NADH + H+ R00704 (R)-lactate:NAD+ oxidoreductase; (R)-Lactate + NAD+ <=> Pyruvate + NADH + H+ R00705 3-oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating); 3-Oxopropanoate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+ R00706 3-oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating); 3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H+ R00707 (S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase; (S)-1-Pyrroline-5-carboxylate + NAD+ + 2 H2O <=> L-Glutamate + NADH + H+ R00708 (S)-1-pyrroline-5-carboxylate:NADP+ oxidoreductase; (S)-1-Pyrroline-5-carboxylate + NADP+ + 2 H2O <=> L-Glutamate + NADPH + H+ R00709 isocitrate:NAD+ oxidoreductase (decarboxylating); Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+ R00710 acetaldehyde:NAD+ oxidoreductase; Acetaldehyde + NAD+ + H2O <=> Acetate + NADH + H+ R00711 acetaldehyde:NADP+ oxidoreductase; Acetaldehyde + NADP+ + H2O <=> Acetate + NADPH + H+ R00713 succinate-semialdehyde:NAD+ oxidoreductase; Succinate semialdehyde + NAD+ + H2O <=> Succinate + NADH + H+ R00714 succinate-semialdehyde:NADP+ oxidoreductase; Succinate semialdehyde + NADP+ + H2O <=> Succinate + NADPH + H+ R00715 N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming); N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADH + H+ R00716 N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming); N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+ R00717 glycolate:NAD+ oxidoreductase; Glycolate + NAD+ <=> Glyoxylate + NADH + H+ R00719 ITP phosphohydrolase; ITP + H2O <=> IDP + Orthophosphate R00720 inosine 5'-triphosphate pyrophosphohydrolase; ITP + H2O <=> IMP + Diphosphate R00722 ATP:IDP phosphotransferase; ATP + IDP <=> ADP + ITP R00723 inosine 5'-tetraphosphate phosphohydrolase; Inosine 5'-tetraphosphate + H2O <=> ITP + Orthophosphate R00724 ITP:pyruvate 2-O-phosphotransferase; ITP + Pyruvate <=> IDP + Phosphoenolpyruvate R00725 ITP:D-glucose 6-phosphotransferase; ITP + D-Glucose <=> IDP + D-Glucose 6-phosphate R00726 ITP:oxaloacetate carboxy-lyase (adding ITP; phosphoenolpyruvate-forming); ITP:oxaloacetate carboxy-lyase (transphosphorylating); ITP + Oxaloacetate <=> IDP + Phosphoenolpyruvate + CO2 R00727 succinate:CoA ligase (IDP-forming); ITP + Succinate + CoA <=> IDP + Orthophosphate + Succinyl-CoA R00728 L-tyrosine phenol-lyase (deaminating; pyruvate-forming); L-Tyrosine + H2O <=> Phenol + Pyruvate + Ammonia R00729 L-tyrosine:oxygen oxidoreductase (deaminating); L-Tyrosine + H2O + Oxygen <=> 3-(4-Hydroxyphenyl)pyruvate + Ammonia + Hydrogen peroxide R00730 L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O R00731 L-tyrosine:oxygen oxidoreductase; L-Tyrosine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + H2O R00732 L-arogenate:NAD+ oxidoreductase; L-Arogenate + NAD+ <=> L-Tyrosine + CO2 + NADH + H+ R00733 L-arogenate:NADP+ oxidoreductase; L-Arogenate + NADP+ <=> L-Tyrosine + CO2 + NADPH + H+ R00734 L-tyrosine:2-oxoglutarate aminotransferase; L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate R00735 L-tyrosine:L-arginine ligase (AMP-forming); ATP + L-Tyrosine + L-Arginine <=> AMP + Diphosphate + Kyotorphin R00736 L-tyrosine carboxy-lyase (tyramine-forming); L-Tyrosine <=> Tyramine + CO2 R00737 L-tyrosine ammonia-lyase (trans-p-hydroxycinnamate-forming); L-Tyrosine <=> 4-Coumarate + Ammonia R00739 L-tyrosine 2,3-aminomutase; L-Tyrosine <=> 3-Amino-3-(4-hydroxyphenyl)propanoate R00740 3-oxopropanoate:NADP+ oxidoreductase (CoA-malonylating); 3-Oxopropanoate + CoA + NADP+ <=> Malonyl-CoA + NADPH + H+ R00742 acetyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA R00743 acetyl-CoA:malonate CoA-transferase; Acetyl-CoA + Malonate <=> Acetate + Malonyl-CoA R00744 3-oxopropionyl-CoA:NAD+ oxidoreductase; Malonyl-CoA + NADPH + H+ <=> 3-Oxopropionyl-CoA + NADP+ + H2O R00746 ethanol:NADP+ oxidoreductase; Ethanol + NADP+ <=> Acetaldehyde + NADPH + H+ R00747 2-phosphonoacetaldehyde phosphonohydrolase; Phosphonoacetaldehyde + H2O <=> Acetaldehyde + Orthophosphate R00748 ethanolamine-phosphate phosphate-lyase (deaminating; acetaldehyde-forming); Ethanolamine phosphate + H2O <=> Acetaldehyde + Ammonia + Orthophosphate R00749 ethanolamine ammonia-lyase (acetaldehyde-forming); Ethanolamine <=> Acetaldehyde + Ammonia R00750 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming); Acetaldehyde + Pyruvate <=> 4-Hydroxy-2-oxopentanoate R00751 L-threonine acetaldehyde-lyase (glycine-forming); L-Threonine <=> Glycine + Acetaldehyde R00753 (S)-lactate acetaldehyde-lyase (formate-forming); (S)-Lactate <=> Formate + Acetaldehyde R00754 ethanol:NAD+ oxidoreductase; Ethanol + NAD+ <=> Acetaldehyde + NADH + H+ R00755 Acetaldehyde + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate R00756 ATP:D-fructose-6-phosphate 1-phosphotransferase; ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate R00758 D-mannitol-1-phosphate:NAD+ 5-oxidoreductase; D-Mannitol 1-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+ R00760 ATP:D-fructose 6-phosphotransferase; ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate R00761 D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming); D-Fructose 6-phosphate + Orthophosphate <=> Acetyl phosphate + D-Erythrose 4-phosphate + H2O R00762 D-fructose-1,6-bisphosphate 1-phosphohydrolase; D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate R00763 beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate R00764 diphosphate:D-fructose-6-phosphate 1-phosphotransferase; Diphosphate + D-Fructose 6-phosphate <=> Orthophosphate + D-Fructose 1,6-bisphosphate R00765 D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate ketol-isomerase(deaminating); D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia R00766 UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase; UDP-glucose + D-Fructose 6-phosphate <=> UDP + Sucrose 6'-phosphate R00767 CTP:D-fructose-6-phosphate 1-phosphotransferase; CTP + D-Fructose 6-phosphate <=> CDP + D-Fructose 1,6-bisphosphate R00768 L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate aminotransferase (hexose isomerizing); L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate R00769 UTP:D-fructose-6-phosphate 1-phosphotransferase; UTP + D-Fructose 6-phosphate <=> UDP + D-Fructose 1,6-bisphosphate R00770 ITP:D-fructose-6-phosphate 1-phosphotransferase; ITP + D-Fructose 6-phosphate <=> IDP + D-Fructose 1,6-bisphosphate R00771 D-glucose-6-phosphate aldose-ketose-isomerase; D-Glucose 6-phosphate <=> D-Fructose 6-phosphate R00772 D-mannose-6-phosphate aldose-ketose-isomerase; D-Mannose 6-phosphate <=> D-Fructose 6-phosphate R00774 urea:carbon-dioxide ligase (ADP-forming); ATP + Urea + HCO3- <=> ADP + Orthophosphate + Urea-1-carboxylate R00775 guanidinoacetate amidohydrolase; Guanidinoacetate + H2O <=> Glycine + Urea R00776 (S)-ureidoglycolate urea-lyase (glyoxylate-forming); (S)-Ureidoglycolate <=> Glyoxylate + Urea R00777 N-amidino-L-aspartate amidinohydrolase; N-Amidino-L-aspartate + H2O <=> L-Aspartate + Urea R00778 urea hydro-lyase (cyanamide-forming); Urea <=> Cyanamide + H2O R00782 L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming); L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia R00783 nitric-oxide:ferricytochrome-c oxidoreductase; Nitric oxide + H2O + Ferricytochrome c <=> Nitrite + Ferrocytochrome c + H+ R00784 nitric-oxide:ferricytochrome-c2 oxidoreductase; Nitric oxide + H2O + Ferricytochrome c2 <=> Nitrite + Ferrocytochrome c2 + H+ R00785 nitric-oxide:oxidized azurin oxidoreductase; Nitric oxide + H2O + Oxidized azurin <=> Nitrite + Reduced azurin + H+ R00787 ammonia:NAD+ oxidoreductase; Ammonia + 3 NAD+ + 2 H2O <=> Nitrite + 3 NADH + 3 H+ R00789 ammonia:NADP+ oxidoreductase; Ammonia + 3 NADP+ + 2 H2O <=> Nitrite + 3 NADPH + 3 H+ R00790 ammonia:ferredoxin oxidoreductase; Ammonia + 2 H2O + 6 Oxidized ferredoxin <=> Nitrite + 6 Reduced ferredoxin + 6 H+ R00791 nitrite:ferredoxin oxidoreductase; Nitrite + H2O + 2 Oxidized ferredoxin <=> Nitrate + 2 Reduced ferredoxin R00792 ferrocytochrome-b:nitrate oxidoreductase; Nitrate + 2 Ferrocytochrome b <=> Nitrite + H2O + 2 Ferricytochrome b R00793 hydroxylamine:oxygen oxidoreductase; Nitrite + H2O <=> Hydroxylamine + Oxygen R00794 nitrite:NAD+ oxidoreductase; NADH:nitrate oxidoreductase; Nitrite + NAD+ + H2O <=> Nitrate + NADH + H+ R00796 nitrite:NADP+ oxidoreductase; NADPH:nitrate oxidoreductase; Nitrite + NADP+ + H2O <=> Nitrate + NADPH + H+ R00798 nitrite:acceptor oxidoreductase; Nitrite + Acceptor + H2O <=> Nitrate + Reduced acceptor R00799 nitroethane:oxygen oxidoreductase; Nitrite + Acetaldehyde + Hydrogen peroxide <=> Nitroethane + Oxygen + H2O R00800 nitrite oxidase; 2 Nitrite + Oxygen <=> 2 Nitrate R00801 sucrose glucohydrolase; Sucrose + H2O <=> D-Fructose + D-Glucose R00802 sucrose alpha-glucohydrolase; Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose R00803 sucrose:phosphate alpha-D-glucosyltransferase; Sucrose + Orthophosphate <=> D-Fructose + D-Glucose 1-phosphate R00804 sugar-phosphate phosphohydrolase; Sugar phosphate + H2O <=> Sugar + Orthophosphate R00805 sucrose-6F-phosphate phosphohydrolase; Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate R00806 UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase; UDP-glucose + D-Fructose <=> UDP + Sucrose R00807 sucrose:(acceptor) 3-oxidoreductase; Sucrose + FAD <=> 3-Ketosucrose + FADH2 R00808 sucrose:(acceptor) 3-oxidoreductase; Sucrose + Acceptor <=> 3-Ketosucrose + Reduced acceptor R00809 UDP-alpha-D-galactose:sucrose 6F-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + Sucrose <=> UDP + 6F-alpha-D-Galactosylsucrose R00810 sucrose glucosylmutase; Sucrose <=> Palatinose R00811 protein-Npi-phospho-L-histidine:sugar phosphotransferase; Sucrose + Protein N(pi)-phospho-L-histidine <=> Sucrose 6-phosphate + Protein histidine R00812 cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase; cis-1,2-Dihydrobenzene-1,2-diol + NAD+ <=> Catechol + NADH + H+ R00813 (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating); (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ <=> Catechol + NADH + CO2 + H+ R00814 trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase; trans-1,2-Dihydrobenzene-1,2-diol + NADP+ <=> Catechol + NADPH + H+ R00815 phenol,NADPH:oxogen oxidoreductase (2-hydroxylating); Phenol + Oxygen + NADPH + H+ <=> Catechol + NADP+ + H2O R00816 catechol:oxygen 2,3-oxidoreductase (decyclizing); Catechol + Oxygen <=> 2-Hydroxymuconate semialdehyde R00817 catechol:oxygen 1,2-oxidoreductase(decyclizing); Catechol + Oxygen <=> cis,cis-Muconate R00818 salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); Salicylate + Oxygen + NADH + H+ <=> Catechol + CO2 + NAD+ + H2O R00821 2,3-dihydroxybenzoate carboxy-lyase; 2,3-Dihydroxybenzoate <=> Catechol + CO2 R00822 3,4-dihydroxybenzoate carboxy-lyase (catechol-forming); protocatechuate carboxy-lyase; 3,4-Dihydroxybenzoate <=> Catechol + CO2 R00823 anthranilate,NADH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating); Anthranilate + Oxygen + NADH + H+ <=> Catechol + Ammonia + CO2 + NAD+ R00825 anthranilate,NADPH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating); Anthranilate + Oxygen + NADPH + H+ <=> Catechol + Ammonia + CO2 + NADP+ R00827 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + Catechol <=> S-Adenosyl-L-homocysteine + o-Methoxyphenol R00828 2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming); 2-Nitrophenol + Oxygen + 2 NADPH + 2 H+ <=> Catechol + Nitrite + 2 NADP+ + H2O R00829 succinyl-CoA:acetyl-CoA C-acyltransferase; beta-ketoadipyl-CoA thiolase; Succinyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoadipyl-CoA R00830 succinyl-CoA:glycine C-succinyltransferase (decarboxylating); Succinyl-CoA + Glycine <=> 5-Aminolevulinate + CoA + CO2 R00832 succinyl-CoA:L-arginine N2-succinyltransferase; Succinyl-CoA + L-Arginine <=> CoA + N2-Succinyl-L-arginine R00833 (R)-methylmalonyl-CoA CoA-carbonylmutase; (R)-Methylmalonyl-CoA <=> Succinyl-CoA R00834 D-sorbitol 6-phosphate:NADP+ 1-oxidoreductase; Sorbitol 6-phosphate + NADP+ <=> D-Glucose 6-phosphate + NADPH + H+ R00835 D-glucose-6-phosphate:NADP+ 1-oxidoreductase; D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+ R00836 UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; UDP-glucose + D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate R00837 alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase; H2O + alpha,alpha'-Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate R00838 maltose-6'-phosphate 6-phosphoglucohydrolase; H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate R00839 6-phospho-beta-D-glucosyl-(1->4)-D-glucose 6-phosphoglucohydrolase; 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O <=> D-Glucose + D-Glucose 6-phosphate R00841 sn-glycerol-3-phosphate phosphohydrolase; sn-Glycerol 3-phosphate + H2O <=> Glycerol + Orthophosphate R00842 sn-glycerol-3-phosphate:NAD+ 2-oxidoreductase; sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+ R00844 sn-glycerol-3-phosphate:NADP+ 2-oxidoreductase; sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+ R00845 sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase; sn-Glycerol 3-phosphate + NADP+ <=> D-Glyceraldehyde 3-phosphate + NADPH + H+ R00846 sn-glycerol-3-phosphate:oxygen 2-oxidoreductase; sn-Glycerol 3-phosphate + Oxygen <=> Glycerone phosphate + Hydrogen peroxide R00847 ATP:glycerol 3-phosphotransferase; ATP + Glycerol <=> ADP + sn-Glycerol 3-phosphate R00848 sn-glycerol-3-phosphate:(acceptor) 2-oxidoreductase; sn-Glycerol 3-phosphate + FAD <=> Glycerone phosphate + FADH2 R00849 sn-glycerol 3-phosphate:quinone oxidoreductase; sn-Glycerol 3-phosphate + Quinone <=> Glycerone phosphate + Hydroquinone R00850 sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase; sn-Glycerol 3-phosphate + D-Glucose <=> Glycerol + D-Glucose 6-phosphate R00851 acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase; sn-Glycerol 3-phosphate + Acyl-CoA <=> 1-Acyl-sn-glycerol 3-phosphate + CoA R00853 UDP-alpha-D-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + 2-(alpha-D-Galactosyl)-sn-glycerol 3-phosphate R00854 UDP-alpha-D-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + alpha-D-Galactosyl-(1,1')-sn-glycerol 3-phosphate R00855 CDPglycerol phosphoglycerohydrolase; CDP-glycerol + H2O <=> CMP + sn-Glycerol 3-phosphate R00856 CTP:sn-glycerol-3-phosphate cytidylyltransferase; CTP + sn-Glycerol 3-phosphate <=> Diphosphate + CDP-glycerol R00857 glycerophosphodiester glycerophosphohydrolase; Glycerophosphodiester + H2O <=> Alcohol + sn-Glycerol 3-phosphate R00858 hydrogen-sulfide:NADP+ oxidoreductase; Hydrogen sulfide + 3 NADP+ + 3 H2O <=> Sulfite + 3 NADPH + 3 H+ R00859 hydrogen-sulfide:ferredoxin oxidoreductase; Hydrogen sulfide + 6 Oxidized ferredoxin + 3 H2O <=> Sulfite + 6 Reduced ferredoxin + 6 H+ R00860 AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming); Sulfite + Acceptor + AMP <=> Adenylyl sulfate + Reduced acceptor R00861 [DsrC protein]-trisulfide,NAD+ oxidoreductase (sulfite-forming); Protein-trisulfide + NAD+ + 3 H2O <=> Protein dithiol + Sulfite + NADH + H+ R00863 3-sulfino-L-alanine 4-carboxy-lyase; 3-Sulfino-L-alanine <=> L-Alanine + Sulfur dioxide R00864 Sulfite + Sulfur <=> Thiosulfate R00865 D-mannitol:ferricytochrome-c 2-oxidoreductase; Mannitol + 2 Ferricytochrome c <=> D-Fructose + 2 Ferrocytochrome c + 2 H+ R00866 ATP:D-fructose 1-phosphotransferase; ATP + D-Fructose <=> ADP + D-Fructose 1-phosphate R00867 ATP:D-fructose 6-phosphotransferase; ATP + D-Fructose <=> ADP + beta-D-Fructose 6-phosphate R00868 D-mannitol:NAD+ 2-oxidoreductase; Mannitol + NAD+ <=> D-Fructose + NADH + H+ R00870 D-mannitol:NADP+ 2-oxidoreductase; Mannitol + NADP+ <=> D-Fructose + NADPH + H+ R00871 D-fructose:NADP+ 5-oxidoreductase; D-Fructose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+ R00872 D-fructose 2-phosphate phosphatase; beta-D-Fructose 2-phosphate + H2O <=> D-Fructose + Orthophosphate R00873 D-fructose:ubiquinone 5-oxidoreductase; D-Fructose + Ubiquinone <=> 5-Dehydro-D-fructose + Ubiquinol R00874 D-glucose:D-fructose oxidoreductase; D-Fructose + D-Glucose <=> D-Glucono-1,5-lactone + D-Sorbitol R00875 D-glucitol:NAD+ 2-oxidoreductase; D-Sorbitol + NAD+ <=> D-Fructose + NADH + H+ R00876 ITP:D-fructose 6-phosphotransferase; ITP + D-Fructose <=> IDP + D-Fructose 6-phosphate R00877 D-mannose aldose-ketose-isomerase; D-Mannose <=> D-Fructose R00878 alpha-D-glucose aldose-ketose-isomerase; alpha-D-Glucose <=> D-Fructose R00879 beta-D-fructan fructohydrolase; Fructan(n+1) + H2O <=> D-Fructose + Fructan(n) R00880 GDP-D-mannose:NAD+ 6-oxidoreductase; GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+ R00881 GDP-mannose mannophosphohydrolase; GDP-mannose + H2O <=> GMP + D-Mannose 1-phosphate R00883 GDP:D-mannose-1-phosphate guanylyltransferase; GDP + D-Mannose 1-phosphate <=> Orthophosphate + GDP-mannose R00885 GTP:alpha-D-mannose-1-phosphate guanylyltransferase; GTP + D-Mannose 1-phosphate <=> Diphosphate + GDP-mannose R00887 GDP-mannose + Mannan(n) <=> GDP + Mannan(n+1) R00888 GDP-alpha-D-mannose 4,6-hydro-lyase (GDP-4-dehydro-alpha-D-rhamnose-forming); GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming); GDP-mannose <=> GDP-4-dehydro-6-deoxy-D-mannose + H2O R00889 GDP-mannose 3,5-epimerase; GDP-mannose <=> GDP-L-galactose R00890 GDPmannose:mannan 1,4-beta-D-mannosyltransferase; GDP-mannose + 1,4-beta-D-Mannan <=> GDP + 1,4-beta-D-Mannan R00891 L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming); L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O R00892 L-cysteine:NAD+ oxidoreductase; NADH:L-cystine oxidoreductase; 2 L-Cysteine + NAD+ <=> L-Cystine + H+ + NADH R00893 L-cysteine:oxygen oxidoreductase; L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine R00894 L-glutamate:L-cysteine gamma-ligase (ADP-forming); ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine R00895 L-cysteine:2-oxoglutarate aminotransferase; L-Cysteine + 2-Oxoglutarate <=> Mercaptopyruvate + L-Glutamate R00896 L-cysteine:2-oxoglutarate aminotransferase; L-Cysteine + 2-Oxoglutarate <=> Mercaptopyruvate + Glutamate R00897 O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide); O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate R00899 L-cysteinylglycine dipeptidase; Cys-Gly + H2O <=> L-Cysteine + Glycine R00900 L-cysteine,glutathione:NADP+ oxidoreductase (disulfide-forming); NADPH:CoA-glutathione oxidoreductase; L-Cysteine + Glutathione + NADP+ <=> S-Glutathionyl-L-cysteine + NADPH R00901 L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming); L-Cysteine + Sulfite <=> Hydrogen sulfide + L-Cysteate R00903 cysteine racemase; L-Cysteine <=> D-Cysteine R00904 3-aminopropanal:NAD+ oxidoreductase; 3-Aminopropanal + NAD+ + H2O <=> beta-Alanine + NADH + H+ R00905 3-ureidopropanoate amidohydrolase; 3-Ureidopropionate + H2O <=> beta-Alanine + CO2 + Ammonia R00906 N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming); beta-Alanopine + NAD+ + H2O <=> beta-Alanine + Pyruvate + NADH + H+ R00907 L-alanine:3-oxopropanoate aminotransferase; L-Alanine + 3-Oxopropanoate <=> Pyruvate + beta-Alanine R00908 beta-alanine:2-oxoglutarate aminotransferase; beta-Alanine + 2-Oxoglutarate <=> 3-Oxopropanoate + L-Glutamate R00909 N-acetyl-beta-alanine amidohydrolase; N-Acetyl-beta-alanine + H2O <=> Acetate + beta-Alanine R00910 L-lysine:beta-alanine ligase (ADP-forming); ATP + L-Lysine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-lysine R00911 beta-alanyl-L-lysine hydrolase; beta-Alanyl-L-lysine + H2O <=> beta-Alanine + L-Lysine R00912 L-arginine:beta-alanine ligase (ADP-forming); ATP + L-Arginine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-arginine R00913 3-guanidinopropanoate amidinopropionase; 3-Guanidinopropanoate + H2O <=> beta-Alanine + Urea R00914 beta-alanine CoA-transferase; beta-Alanine <=> beta-Alanyl-CoA R00915 beta-Alanine <=> Quinolinate R00916 beta-Alanine <=> beta-Nitropropanoate R00917 beta-aminopropionitrile aminohydrolase; beta-Alanine + Ammonia <=> 3-Aminopropiononitrile + 2 H2O R00918 propanoyl-CoA:(2S)-methylmalonyl-CoA malonyltransferase (cyclizing); propanoyl-CoA:(2S)-methylmalonyl-CoA 2-C-acyltransferase (decarboxylating, oxoacyl-reducing and cyclizing); Propanoyl-CoA + 6 (S)-Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 6-Deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+ R00919 propanoyl-CoA:NADP+ 2-oxidoreductase; acrylyl-CoA reductase (NADPH); Propanoyl-CoA + NADP+ <=> Propenoyl-CoA + NADPH + H+ R00920 propanoate:CoA ligase (ADP-forming); ATP + Propanoate + CoA <=> ADP + Orthophosphate + Propanoyl-CoA R00921 propanoyl-CoA:phosphate propanoyltransferase; Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA R00922 2-methyl-3-oxopropanoate:NAD+ oxidoreductase (CoA-propanoylating); 2-Methyl-3-oxopropanoate + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H+ R00923 (S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming); (S)-Methylmalonyl-CoA <=> Propanoyl-CoA + CO2 R00925 propanoate:CoA ligase (AMP-forming); ATP + Propanoate + CoA <=> AMP + Diphosphate + Propanoyl-CoA R00926 propionyladenylate:CoA propionyltransferase; Propionyladenylate + CoA <=> AMP + Propanoyl-CoA R00927 acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA thiolase; Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA R00928 acetyl-CoA:propanoate CoA-transferase; Acetyl-CoA + Propanoate <=> Acetate + Propanoyl-CoA R00930 (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase; (S)-Methylmalonyl-CoA + Pyruvate <=> Propanoyl-CoA + Oxaloacetate R00931 propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming); 2-methylcitrate oxaloacetate-lyase; 2-Methylcitrate + CoA <=> Propanoyl-CoA + Oxaloacetate + H2O R00932 propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming); 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating); 2-Hydroxyglutarate + CoA <=> Propanoyl-CoA + H2O + Glyoxylate R00934 L-erythro-3-methylmalyl-CoA glyoxylate-lyase (propanoyl-CoA-forming); Propanoyl-CoA + Glyoxylate <=> L-erythro-3-Methylmalyl-CoA R00935 (S)-methylmalonate semialdehyde:NAD+ oxidoreductase (CoA-propanoylating); (S)-Methylmalonate semialdehyde + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H+ R00936 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase; Tetrahydrofolate + NAD+ <=> Dihydrofolate + NADH + H+ R00937 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase; Tetrahydrofolate + 2 NAD+ <=> Folate + 2 NADH + 2 H+ R00939 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase; Tetrahydrofolate + NADP+ <=> Dihydrofolate + NADPH + H+ R00940 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase; Tetrahydrofolate + 2 NADP+ <=> Folate + 2 NADPH + 2 H+ R00941 10-formyltetrahydrofolate:NADP+ oxidoreductase; 10-Formyltetrahydrofolate + NADP+ + H2O <=> Tetrahydrofolate + CO2 + NADPH + H+ R00942 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming); ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate R00943 formate:tetrahydrofolate ligase (ADP-forming); Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate R00944 10-formyltetrahydrofolate amidohydrolase; 10-Formyltetrahydrofolate + H2O <=> Formate + Tetrahydrofolate R00945 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase; 5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine R00946 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase; 5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine R00947 alpha-D-glucose-1-phosphate phosphohydrolase; D-Glucose 1-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate R00948 ATP:alpha-D-glucose-1-phosphate adenylyltransferase; ATP + D-Glucose 1-phosphate <=> Diphosphate + ADP-glucose R00949 ATP:D-glucose-1-phosphate 6-phosphotransferase; ATP + D-Glucose 1-phosphate <=> ADP + alpha-D-Glucose 1,6-bisphosphate R00951 ADP-glucose glucose-1-phosphohydrolase; ADP-glucose + H2O <=> AMP + D-Glucose 1-phosphate R00952 cellobiose:phosphate alpha-D-glucosyltransferase; Cellobiose + Orthophosphate <=> D-Glucose 1-phosphate + D-Glucose R00953 3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase; Laminaribiose + Orthophosphate <=> D-Glucose + D-Glucose 1-phosphate R00954 GTP:alpha-D-glucose-1-phosphate guanylyltransferase; GTP + D-Glucose 1-phosphate <=> Diphosphate + GDP-glucose R00955 UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase; UDP-glucose + alpha-D-Galactose 1-phosphate <=> D-Glucose 1-phosphate + UDP-alpha-D-galactose R00956 CTP:alpha-D-glucose-1-phosphate cytidylyltransferase; CTP + D-Glucose 1-phosphate <=> Diphosphate + CDP-glucose R00957 alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating); 2 D-Glucose 1-phosphate + H2O <=> Maltose + 2 Orthophosphate R00959 alpha-D-glucose 1-phosphate 1,6-phosphomutase; D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate R00960 D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase; 2 D-Glucose 1-phosphate <=> alpha-D-Glucose 1,6-bisphosphate + D-Glucose R00961 IDP phosphohydrolase; inosine diphosphate phosphatase; IDP + H2O <=> IMP + Orthophosphate R00963 uridine 5'-monophosphate phosphohydrolase; UMP + H2O <=> Uridine + Orthophosphate R00964 ATP:uridine 5'-phosphotransferase; ATP + Uridine <=> ADP + UMP R00965 orotidine-5'-phosphate carboxy-lyase (UMP-forming); Orotidine 5'-phosphate <=> UMP + CO2 R00966 UMP:diphosphate phospho-alpha-D-ribosyltransferase; UMP + Diphosphate <=> Uracil + 5-Phospho-alpha-D-ribose 1-diphosphate R00968 GTP:uridine 5'-phosphotransferase; GTP + Uridine <=> GDP + UMP R00969 P1,P4-bis(5'-uridyl)-tetraphosphate uridylohydrolase; P1,P4-Bis(5'-uridyl) tetraphosphate + H2O <=> UTP + UMP R00973 uracil-5-carboxylate carboxy-lyase (uracil-forming); Uracil 5-carboxylate <=> Uracil + CO2 R00974 cytosine aminohydrolase; Cytosine + H2O <=> Uracil + Ammonia R00975 5,6-dihydrouracil:oxygen oxidoreductase; 5,6-Dihydrouracil + Oxygen <=> Uracil + Hydrogen peroxide R00976 uracil:acceptor oxidoreductase; Uracil + Acceptor + H2O <=> Barbiturate + Reduced acceptor R00977 5,6-dihydrouracil:NAD+ oxidoreductase; 5,6-Dihydrouracil + NAD+ <=> Uracil + NADH + H+ R00978 5,6-dihydrouracil:NADP+ oxidoreductase; 5,6-Dihydrouracil + NADP+ <=> Uracil + NADPH + H+ R00980 anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating); Anthranilate + Oxygen + NADPH + H+ <=> 2,3-Dihydroxybenzoate + Ammonia + NADP+ R00982 anthranilate:CoA ligase (AMP-forming); ATP + Anthranilate + CoA <=> AMP + Diphosphate + Anthraniloyl-CoA R00983 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing); 2,3-Dihydroxyindole + Oxygen <=> Anthranilate + CO2 R00984 S-adenosyl-L-methionine:anthranilate N-methyltransferase; S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + N-Methylanthranilate R00985 chorismate pyruvate-lyase (amino-accepting; anthranilate-forming); Chorismate + Ammonia <=> Anthranilate + Pyruvate + H2O R00986 chorismate pyruvate-lyase (amino-accepting); Chorismate + L-Glutamine <=> Anthranilate + Pyruvate + L-Glutamate R00987 L-kynurenine hydrolase; L-Kynurenine + H2O <=> Anthranilate + L-Alanine R00988 N-formylanthranilate amidohydrolase; Formylanthranilate + H2O <=> Formate + Anthranilate R00989 malonyl-CoA:anthranilate N-malonyltransferase; Malonyl-CoA + Anthranilate <=> CoA + N-Malonylanthranilate R00990 2-aminobenzoate carboxy-lyase; Anthranilate <=> Aniline + CO2 R00991 Anthranilate <=> 2-Formaminobenzoylacetate R00993 2-oxobutanoate:oxygen 2-oxidoreductase (phosphorylating); 2-Oxobutanoate + Orthophosphate + Oxygen <=> Propanoyl phosphate + CO2 + Hydrogen peroxide R00994 (2R,3S)-3-methylmalate:NAD+ oxidoreductase; 2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+ R00995 methyloxaloacetate carboxy-lyase (2-oxobutanoate-forming); Methyloxaloacetate <=> 2-Oxobutanoate + CO2 R00996 L-threonine ammonia-lyase (2-oxobutanoate-forming); L-Threonine <=> 2-Oxobutanoate + Ammonia R00997 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing); 1-aminocyclopropane-1-carboxylate endolyase (deaminating); 1-Aminocyclopropane-1-carboxylate + H2O <=> 2-Oxobutanoate + Ammonia R00998 acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); (R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acylating); (R)-2-Ethylmalate + CoA <=> Acetyl-CoA + H2O + 2-Oxobutanoate R00999 O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming); O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia R01000 2-hydroxybutyrate:NAD+ oxidoreductase; 2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H+ R01001 L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming); L-Cystathionine + H2O <=> L-Cysteine + Ammonia + 2-Oxobutanoate R01003 dolichyl-phosphate phosphohydrolase; Dolichyl phosphate + H2O <=> Dolichol + Orthophosphate R01004 dolichyl-diphosphate phosphohydrolase; Dolichyl diphosphate + H2O <=> Dolichyl phosphate + Orthophosphate R01005 UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase; UDP-glucose + Dolichyl phosphate <=> UDP + Dolichyl beta-D-glucosyl phosphate R01006 dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase; Dolichyl beta-D-glucosyl phosphate + H2O <=> Dolichyl phosphate + D-Glucose R01007 UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol R01008 UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Archaeal dolichyl phosphate <=> UDP + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate R01009 GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase; GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose R01010 glycerone phosphate phosphohydrolase; Glycerone phosphate + H2O <=> Glycerone + Orthophosphate R01011 ATP:glycerone phosphotransferase; ATP + Glycerone <=> ADP + Glycerone phosphate R01012 phosphoenolpyruvate:glycerone phosphotransferase; Phosphoenolpyruvate + Glycerone <=> Pyruvate + Glycerone phosphate R01013 acyl-CoA:glycerone-phosphate O-acyltransferase; Acyl-CoA + Glycerone phosphate <=> CoA + Acylglycerone phosphate R01014 erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming); Erythrulose 1-phosphate <=> Glycerone phosphate + Formaldehyde R01015 D-glyceraldehyde-3-phosphate aldose-ketose-isomerase; D-Glyceraldehyde 3-phosphate <=> Glycerone phosphate R01016 glycerone-phosphate phosphate-lyase (methylglyoxal-forming); Glycerone phosphate <=> Methylglyoxal + Orthophosphate R01018 CTP:dolichol O-phosphotransferase; CTP + Dolichol <=> CDP + Dolichyl phosphate R01019 acetaldehyde:pyrroloquinoline-quinone oxidoreductase; PQQ + Acetaldehyde + H2O <=> PQQH2 + Acetate R01021 ATP:choline phosphotransferase; ATP + Choline <=> ADP + Choline phosphate R01022 choline:oxygen 1-oxidoreductase; Choline + Oxygen <=> Betaine aldehyde + Hydrogen peroxide R01023 acetyl-CoA:choline O-acetyltransferase; Acetyl-CoA + Choline <=> CoA + Acetylcholine R01025 choline:acceptor 1-oxidoreductase; Choline + Acceptor <=> Betaine aldehyde + Reduced acceptor R01026 acetylcholine aectylhydrolase; Acetylcholine + H2O <=> Choline + Acetate R01027 3'-phosphoadenylyl-sulfate:choline sulfotransferase; 3'-Phosphoadenylyl sulfate + Choline <=> Adenosine 3',5'-bisphosphate + Choline sulfate R01028 choline sulfate sulfohydrolase; Choline sulfate + H2O <=> Choline + Sulfate R01029 acylcholine acylhydrolase; Acylcholine + H2O <=> Choline + Carboxylate R01030 sn-glycero-3-phosphocholine glycerophosphohydrolase; sn-Glycero-3-phosphocholine + H2O <=> Choline + sn-Glycerol 3-phosphate R01031 3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming); 3-Chloro-D-alanine + H2O <=> Pyruvate + Hydrochloric acid + Ammonia R01032 3-chloro-L-alanine chloride-lyase (deaminating; pyruvate-forming); Cl- + Pyruvate + Ammonia <=> 3-Chloro-L-alanine + H2O R01033 2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating); 2-Chlorobenzoate + Oxygen + NADH <=> Cl- + Catechol + NAD+ + CO2 R01034 glycerol:NAD+ 2-oxidoreductase; Glycerol + NAD+ <=> Glycerone + NADH + H+ R01036 glycerol:NAD+ oxidoreductase; Glycerol + NAD+ <=> D-Glyceraldehyde + NADH + H+ R01039 glycerol:NADP+ 2-oxidoreductase (glycerone-forming); Glycerol + NADP+ <=> Glycerone + NADPH + H+ R01041 glycerol:NADP+ oxidoreductase; Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H+ R01043 glycerol-2-phosphate phosphohydrolase; Glycerol 2-phosphate + H2O <=> Glycerol + Orthophosphate R01044 diphosphate:glycerol 1-phosphotransferase; Diphosphate + Glycerol <=> Orthophosphate + sn-Glycerol 1-phosphate R01045 glycerol:(acceptor) 1-oxidoreductase; glycerol:acceptor 2-oxidoreductase; Glycerol + Acceptor <=> Glycerone + Reduced acceptor R01047 glycerol hydro-lyase (3-hydroxypropanal-forming); Glycerol <=> 3-Hydroxypropanal + H2O R01049 ATP:D-ribose-5-phosphate diphosphotransferase; ATP + D-Ribose 5-phosphate <=> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate R01050 ATP:D-ribose-5-phosphate 1-phosphotransferase; ATP + D-Ribose 5-phosphate <=> ADP + D-Ribose 1,5-bisphosphate R01051 ATP:D-ribose 5-phosphotransferase; ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate R01052 ADP:D-ribose-5-phosphate adenylyltransferase; ADP + D-Ribose 5-phosphate <=> Orthophosphate + ADP-ribose R01053 ribose-5-phosphate:ammonia ligase (ADP-forming); ATP + D-Ribose 5-phosphate + Ammonia <=> ADP + Orthophosphate + 5-Phosphoribosylamine R01054 ADP-ribose ribophosphohydrolase; ADP-ribose + H2O <=> AMP + D-Ribose 5-phosphate R01055 uracil hydro-lyase (adding D-ribose 5-phosphate;pseudouridine-5'-phosphate-forming); Uracil + D-Ribose 5-phosphate <=> Pseudouridine 5'-phosphate + H2O R01056 D-ribose-5-phosphate aldose-ketose-isomerase; D-Ribose 5-phosphate <=> D-Ribulose 5-phosphate R01057 D-ribose 1,5-phosphomutase; alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate R01058 D-glyceraldehyde 3-phosphate:NADP+ oxidoreductase; D-Glyceraldehyde 3-phosphate + NADP+ + H2O <=> 3-Phospho-D-glycerate + NADPH + H+ R01059 ATP:D-glyceraldehyde 3-phosphotransferase; ATP + D-Glyceraldehyde <=> ADP + D-Glyceraldehyde 3-phosphate R01061 D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating); D-Glyceraldehyde 3-phosphate + Orthophosphate + NAD+ <=> 3-Phospho-D-glyceroyl phosphate + NADH + H+ R01063 D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating); D-Glyceraldehyde 3-phosphate + Orthophosphate + NADP+ <=> 3-Phospho-D-glyceroyl phosphate + NADPH + H+ R01064 2-dehydro-3-deoxy-6-phospho-D-galactonate D-glyceraldehyde-3-phospho-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-6-phospho-D-galactonate <=> Pyruvate + D-Glyceraldehyde 3-phosphate R01066 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); 2-Deoxy-D-ribose 5-phosphate <=> D-Glyceraldehyde 3-phosphate + Acetaldehyde R01067 D-fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate R01068 D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate R01069 D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); D-Tagatose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate R01070 beta-D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); beta-D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate R01071 1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase; 1-(5-Phospho-D-ribosyl)-ATP + Diphosphate <=> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate R01072 5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating); 5-Phosphoribosylamine + Diphosphate + L-Glutamate <=> L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O R01073 N-(5-phospho-D-ribosyl)anthranilate:pyrophosphate phosphoribosyl-transferase; N-(5-Phospho-D-ribosyl)anthranilate + Diphosphate <=> Anthranilate + 5-Phospho-alpha-D-ribose 1-diphosphate R01074 biotin:CoA ligase (AMP-forming); biotin:apo-[carboxylase] ligase (AMP-forming); ATP:biotin adenylyltransferase; ATP + Biotin <=> Diphosphate + Biotinyl-5'-AMP R01075 biotin:CoA ligase (AMP-forming); ATP + Biotin + CoA <=> AMP + Diphosphate + Biotinyl-CoA R01077 N6-D-biotinyl-L-lysine amidohydrolase; Biocytin + H2O <=> Biotin + L-Lysine R01078 dethiobiotin:sulfur sulfurtransferase; Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine R01079 D-ribose:NADP+ 1-oxidoreductase; D-Ribose + NADP+ + H2O <=> D-Ribonate + NADPH + H+ R01080 uridine ribohydrolase; Uridine + H2O <=> Uracil + D-Ribose R01081 D-ribose aldose-ketose-isomerase; D-Ribose <=> D-Ribulose R01082 (S)-malate hydro-lyase (fumarate-forming); (S)-Malate <=> Fumarate + H2O R01083 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming); N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP R01085 3-fumarylpyruvate fumarylhydrolase; 3-Fumarylpyruvate + H2O <=> Fumarate + Pyruvate R01086 2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming); N-(L-Arginino)succinate <=> Fumarate + L-Arginine R01087 maleate cis-trans-isomerase; Maleic acid <=> Fumarate R01088 L-leucine:NAD+ oxidoreductase (deaminating); L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+ R01089 acetyl-CoA:L-leucine N-acetyltransferase; Acetyl-CoA + L-Leucine <=> CoA + N-Acetyl-L-leucine R01090 L-leucine:2-oxoglutarate aminotransferase; L-Leucine + 2-Oxoglutarate <=> 4-Methyl-2-oxopentanoate + L-Glutamate R01091 (2S)-alpha-leucine 2,3-aminomutase; L-Leucine <=> (3R)-beta-Leucine R01092 ATP:alpha-D-galactose 1-phosphotransferase; ATP + alpha-D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate R01093 galactitol:NAD+ 1-oxidoreductase; D-Galactose + NADH + H+ <=> Galactitol + NAD+ R01094 D-galactose:NAD+ 1-oxidoreductase; D-Galactose + NAD+ <=> D-Galactono-1,4-lactone + NADH + H+ R01095 galactitol:NADP+ 1-oxidoreductase; D-Galactose + NADPH + H+ <=> Galactitol + NADP+ R01096 D-galactose:NADP+ 1-oxidoreductase; D-Galactose + NADP+ <=> D-Galactono-1,5-lactone + NADPH + H+ R01097 D-galactose:NADP+ 1-oxidoreductase; D-Galactose + NADP+ <=> D-Galactono-1,4-lactone + NADPH + H+ R01098 D-galactose:oxygen 6-oxidoreductase; D-Galactose + Oxygen + H2O <=> D-Galactonate + Hydrogen peroxide R01099 D-galactose:oxygen 6-oxidoreductase; D-Galactose + Oxygen <=> D-galacto-Hexodialdose + Hydrogen peroxide R01100 lactose galactohydrolase; Lactose + H2O <=> D-Glucose + beta-D-Galactose R01101 melibiose galactohydrolase; Melibiose + H2O <=> D-Galactose + D-Glucose R01103 raffinose galactohydrolase; Raffinose + H2O <=> D-Galactose + Sucrose R01104 galactosylglycerol galactohydrolase; 3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol R01105 galactan galactohydrolase; Galactan + H2O <=> D-Galactose + Galactan R01106 nitrite:(acceptor) oxidoreductase; 2 Ferricytochrome c + Nitrite + H2O <=> Nitrate + 2 Ferrocytochrome c + 2 H+ R01108 glutathione:dehydroascorbate oxidoreductase; Dehydroascorbate + 2 Glutathione <=> Glutathione disulfide + Ascorbate R01109 glutathione:cystine oxidoreductase; Cystine + 2 Glutathione <=> Glutathione disulfide + 2 Cysteine R01110 glutathione:homocystine oxidoreductase; Homocystine + 2 Glutathione <=> Glutathione disulfide + 2 Homocysteine R01111 coenzyme A:glutathione-disulfide oxidoreductase; CoA + Glutathione disulfide <=> CoA-glutathione + Glutathione R01113 glutathione:L-cystine oxidoreductase; L-Cystine + 2 Glutathione <=> Glutathione disulfide + 2 L-Cysteine R01115 CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating); CMP-N-acetylneuraminate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> CMP-N-glycoloylneuraminate + 2 Ferricytochrome b5 + H2O R01117 CTP:N-acetylneuraminate cytidylyltransferase; CTP + N-Acetylneuraminate <=> Diphosphate + CMP-N-acetylneuraminate R01119 CMP-N-acetylneuraminate <=> Colominic acid(non-reducing N- or O-acylneuraminyl residue) R01120 CMP-N-acetylneuraminate <=> Glycolipid R01121 ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming); ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating); ATP + (R)-5-Diphosphomevalonate <=> ADP + Orthophosphate + Isopentenyl diphosphate + CO2 R01122 delta2-isopentenyl-diphosphate:tRNA isopentenyltransferase; Dimethylallyl diphosphate + tRNA adenine <=> Diphosphate + tRNA containing 6-isopentenyladenosine R01123 isopentenyl-diphosphate Delta3-Delta2-isomerase; Isopentenyl diphosphate <=> Dimethylallyl diphosphate R01126 inosine 5'-monophosphate phosphohydrolase; IMP + H2O <=> Inosine + Orthophosphate R01127 IMP 1,2-hydrolase (decyclizing); IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide R01128 5'-inosinate phosphoribohydrolase; IMP + H2O <=> Hypoxanthine + D-Ribose 5-phosphate R01130 IMP:NAD+ oxidoreductase; IMP + NAD+ + H2O <=> Xanthosine 5'-phosphate + NADH + H+ R01131 ATP:inosine 5'-phosphotransferase; ATP + Inosine <=> ADP + IMP R01132 IMP:diphosphate phospho-D-ribosyltransferase; IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate R01134 inosine-5'-phosphate:NADP+ oxidoreductase (aminating); NADH:guanosine-5'-phosphate oxidoreductase (deaminating); IMP + Ammonia + NADP+ <=> GMP + NADPH + H+ R01135 IMP:L-aspartate ligase (GDP-forming); GTP + IMP + L-Aspartate <=> GDP + Orthophosphate + N6-(1,2-Dicarboxyethyl)-AMP R01137 ATP:dADP phosphotransferase; ATP + dADP <=> ADP + dATP R01138 dATP:pyruvate 2-O-phosphotransferase; dATP + Pyruvate <=> dADP + Phosphoenolpyruvate R01139 dATP:D-glucose 6-phosphotransferase; dATP + D-Glucose <=> dADP + D-Glucose 6-phosphate R01140 dATP:D-fructose 6-phosphotransferase; dATP + D-Fructose <=> dADP + D-Fructose 6-phosphate R01142 methane,NADH:oxygen oxidoreductase (hydroxylating); Methane + Oxygen + NADH + H+ <=> Methanol + NAD+ + H2O R01143 methane,NADPH:oxygen oxidoreductase (hydroxylating); Methane + Oxygen + NADPH + H+ <=> Methanol + NADP+ + H2O R01144 oxaloacetate-4-methyl-ester oxaloacetohydrolase; Oxaloacetate 4-methyl ester + H2O <=> Oxaloacetate + Methanol R01145 monomethyl-sulfate sulfohydrolase; Monomethyl sulfate + H2O <=> Methanol + Sulfate R01146 methanol:ferricytochrome-c oxidoreductase; methanol dehydrogenase; Methanol + 2 Ferricytochrome cL <=> Formaldehyde + 2 Ferrocytochrome cL + 2 H+ R01147 pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase; Pyridoxamine phosphate + Pyruvate <=> Pyridoxal phosphate + D-Alanine R01148 D-alanine:2-oxoglutarate aminotransferase; D-Alanine + 2-Oxoglutarate <=> Pyruvate + D-Glutamate R01149 L-glutamine:D-alanine gamma-glutamyltransferase; D-Alanine + L-Glutamine <=> Ammonia + gamma-L-Glutamyl-D-alanine R01150 D-alanine:D-alanine ligase (ADP-forming); ATP + 2 D-Alanine <=> ADP + Orthophosphate + D-Alanyl-D-alanine R01151 putrescine:oxygen oxidoreductase (deaminating); Putrescine + Oxygen + H2O <=> 4-Aminobutyraldehyde + Ammonia + Hydrogen peroxide R01152 N-carbamoylputrescine amidohydrolase; N-Carbamoylputrescine + H2O <=> Putrescine + CO2 + Ammonia R01153 S-adenosyl-L-methionine:putrescine N-methyltransferase; S-Adenosyl-L-methionine + Putrescine <=> S-Adenosyl-L-homocysteine + N-Methylputrescine R01154 acetyl-CoA:putrescine N-acetyltransferase; Acetyl-CoA + Putrescine <=> CoA + N-Acetylputrescine R01155 putrescine:2-oxoglutarate aminotransferase; Putrescine + 2-Oxoglutarate <=> 4-Aminobutyraldehyde + L-Glutamate R01156 N-acetylputrescine acetylhydrolase; N-Acetylputrescine + H2O <=> Acetate + Putrescine R01157 agmatine amidinohydrolase; Agmatine + H2O <=> Putrescine + Urea R01158 L-histidinol:NAD+ oxidoreductase; L-Histidinol + 2 NAD+ + H2O <=> L-Histidine + 2 NADH + 2 H+ R01159 S-adenosyl-L-methionine:L-histidine N-methyltransferase; L-Histidine + S-Adenosyl-L-methionine <=> N(pi)-Methyl-L-histidine + S-Adenosyl-L-homocysteine R01160 acetyl-CoA:L-histidine N-acetyltransferase; Acetyl-CoA + L-Histidine <=> CoA + N-Acetyl-L-histidine R01161 L-histidine:2-oxoglutarate aminotransferase; L-Histidine + 2-Oxoglutarate <=> Imidazol-5-yl-pyruvate + L-Glutamate R01163 L-histidinal:NAD+ oxidoreductase; L-Histidinal + H2O + NAD+ <=> L-Histidine + NADH + H+ R01164 L-histidine:beta-alanine ligase (ADP-forming); ATP + L-Histidine + beta-Alanine <=> ADP + Orthophosphate + Carnosine R01166 Nalpha-(beta-alanyl)-L-histidine hydrolase; Carnosine + H2O <=> beta-Alanine + L-Histidine R01167 L-histidine carboxy-lyase (histamine-forming); L-Histidine <=> Histamine + CO2 R01168 L-histidine ammonia-lyase (urocanate-forming); L-Histidine <=> Urocanate + Ammonia R01169 S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase; L-Histidine + 3 S-Adenosyl-L-methionine + H+ <=> Hercynine + 3 S-Adenosyl-L-homocysteine R01171 butanoyl-CoA:NAD+ trans-2-oxidoreductase; Butanoyl-CoA + NAD+ <=> Crotonoyl-CoA + NADH + H+ R01172 butanal:NAD+ oxidoreductase (CoA-acylating); Butanal + CoA + NAD+ <=> Butanoyl-CoA + NADH + H+ R01173 butanal:NADP+ oxidoreductase (CoA-acylating); Butanal + CoA + NADP+ <=> Butanoyl-CoA + NADPH + H+ R01174 butanoyl-CoA:phosphate butanoyltransferase; Butanoyl-CoA + Orthophosphate <=> CoA + Butanoylphosphate R01175 butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA R01176 butanoate:CoA ligase (AMP-forming); ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA R01177 butanoyl-CoA:acetyl-CoA C-butanoyltransferase; Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA R01178 short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein R01179 butanoyl-CoA:acetate CoA-transferase; Butanoyl-CoA + Acetate <=> Butanoic acid + Acetyl-CoA R01180 butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming); 3-ethylmalate glyoxylate-lyase (CoA-butanoylating); 3-Ethylmalate + CoA <=> Butanoyl-CoA + H2O + Glyoxylate R01181 2-methylpropanoyl-CoA CoA-carbonylmutase; 2-Methylpropanoyl-CoA <=> Butanoyl-CoA R01183 myo-inositol:NAD+ 2-oxidoreductase; myo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+ R01184 myo-inositol:oxygen oxidoreductase; myo-Inositol + Oxygen <=> D-Glucuronate + H2O R01185 1D-myo-inositol 1-phosphate phosphohydrolase; Inositol 1-phosphate + H2O <=> myo-Inositol + Orthophosphate R01186 1D-myo-inositol 4-phosphate phosphohydrolase; myo-Inositol 4-phosphate + H2O <=> myo-Inositol + Orthophosphate R01187 1D-myo-inositol 3-phosphate phosphohydrolase; 1D-myo-Inositol 3-phosphate + H2O <=> myo-Inositol + Orthophosphate R01188 S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase; S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + D-Bornesitol R01189 S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase; S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + L-Bornesitol R01190 S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase; S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + 4-O-Methyl-myo-inositol R01192 UDP-alpha-D-galactose:myo-inositol 3-alpha-D-galactosyltransferase; UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + myo-Inositol <=> UDP + alpha-D-Galactosyl-(1->3)-1D-myo-inositol R01193 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase; sn-Glycero-3-phospho-1-inositol + H2O <=> myo-Inositol + sn-Glycerol 3-phosphate R01194 3-O-alpha-D-galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-galactosyl-myo-inositol galactohydrolase; alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose R01195 ferredoxin:NADP+ oxidoreductase; 2 Reduced ferredoxin + NADP+ + H+ <=> 2 Oxidized ferredoxin + NADPH R01196 pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating); 2 Reduced ferredoxin + Acetyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + Pyruvate + CoA R01197 2-oxoglutarate:ferredoxin oxidoreductase (decarboxylating); 2 Reduced ferredoxin + Succinyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + 2-Oxoglutarate + CoA R01199 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating); 2 Oxidized ferredoxin + 2-Oxobutanoate + CoA <=> 2 Reduced ferredoxin + Propanoyl-CoA + CO2 + 2 H+ R01200 N-acetyl-D-glucosamine amidohydrolase; N-Acetyl-D-glucosamine + H2O <=> D-Glucosamine + Acetate R01201 ATP:N-acetyl-D-glucosamine 6-phosphotransferase; ATP + N-Acetyl-D-glucosamine <=> ADP + N-Acetyl-D-glucosamine 6-phosphate R01202 N-acetyl-D-glucosamine:NAD+ 1-oxidoreductase; N-Acetyl-alpha-D-glucosamine + NAD+ + H2O <=> N-Acetyl-D-glucosaminate + NADH + H+ R01203 N-acetyl-D-glucosamine:oxygen 1-oxidoreductase; N-Acetyl-D-glucosamine + Oxygen + H2O <=> N-Acetyl-D-glucosaminate + Hydrogen peroxide R01204 acetyl-CoA:D-glucosamine N-acetyltransferase; Acetyl-CoA + D-Glucosamine <=> CoA + N-Acetyl-D-glucosamine R01205 UDP-alpha-D-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-D-glucosamine <=> UDP + N-Acetyllactosamine R01206 [1,4-(N-acetyl-beta-D-glucosaminyl)]n glycanohydrolase; Chitin + H2O <=> N-Acetyl-D-glucosamine + Chitin R01207 N-acetyl-D-glucosamine 2-epimerase; N-Acetyl-D-glucosamine <=> N-Acetyl-D-mannosamine R01209 2,3-dihydroxy-3-methylbutanoate hydro-lyase; 2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O R01210 3-methyl-2-oxobutanoate:NAD+ oxidoreductase (CoA-mehtylpropanoylating); 3-Methyl-2-oxobutanoic acid + CoA + NAD+ <=> 2-Methylpropanoyl-CoA + CO2 + NADH + H+ R01211 (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating); (R)-3,3-Dimethylmalate + NAD+ <=> 3-Methyl-2-oxobutanoic acid + CO2 + NADH + H+ R01212 L-valine:NADP+ oxidoreductase (deaminating); L-Valine + NADP+ + H2O <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADPH + H+ R01213 acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating); alpha-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O R01214 L-valine:2-oxoglutarate aminotransferase; L-Valine + 2-Oxoglutarate <=> 3-Methyl-2-oxobutanoic acid + L-Glutamate R01215 L-valine:pyruvate aminotransferase; L-Valine + Pyruvate <=> 3-Methyl-2-oxobutanoic acid + L-Alanine R01216 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming); 2-Dehydropantoate <=> 3-Methyl-2-oxobutanoic acid + Formaldehyde R01217 5-methyltetrahydrofolate:ferredoxin oxidoreductase; 5,10-Methylenetetrahydrofolate + 2 Reduced ferredoxin + 2 H+ <=> 5-Methyltetrahydrofolate + 2 Oxidized ferredoxin R01218 5,10-methylenetetrahydrofolate:NAD+ oxidoreductase; 5,10-Methylenetetrahydrofolate + NAD+ <=> 5,10-Methenyltetrahydrofolate + NADH R01220 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase; 5,10-Methylenetetrahydrofolate + NADP+ <=> 5,10-Methenyltetrahydrofolate + NADPH R01221 glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system; Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+ R01224 5-methyltetrahydrofolate:NADP+ oxidoreductase; 5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+ R01225 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase; 5,10-Methylenetetrahydrofolate + D-Alanine + H2O <=> Tetrahydrofolate + 2-Methylserine R01226 5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase; 5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O <=> Tetrahydrofolate + 2-Dehydropantoate R01227 guanosine 5'-monophosphate phosphohydrolase; GMP + H2O <=> Guanosine + Orthophosphate R01228 ATP:guanosine 5'-phosphotransferase; ATP + Guanosine <=> ADP + GMP R01229 GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase; GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate R01230 xanthosine-5'-phosphate:ammonia ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP R01231 xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate R01232 P1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase; P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O <=> GTP + GMP R01233 GDPglucose sugarphosphohydrolase; GDP-glucose + H2O <=> GMP + D-Glucose 1-phosphate R01234 guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase; 3',5'-Cyclic GMP + H2O <=> GMP R01235 S-adenosyl-L-methionine:thiol S-methyltransferase; Thiol + S-Adenosyl-L-methionine <=> Methyl thioether + S-Adenosyl-L-homocysteine R01236 3'-phosphoadenylylsulfate:thiol S-sulfotransferase; 3'-Phosphoadenylyl sulfate + Thiol <=> Adenosine 3',5'-bisphosphate + S-Alkyl thiosulfate R01237 thioglucoside glucohydrolase; Thioglucoside + H2O <=> Thiol + Sugar R01238 4-hydroxybenzoate carboxy-lyase (phenol-forming); 4-Hydroxybenzoate <=> Phenol + CO2 R01239 S-adenosyl-L-methionine:phenol O-methyltransferase; S-Adenosyl-L-methionine + Phenol <=> S-Adenosyl-L-homocysteine + Anisole R01240 UDP-glucose:phenol beta-D-glucosyltransferase; UDP-glucose + Phenol <=> UDP + Aryl beta-D-glucoside R01241 phenyl acetate acetylhydrolase; Phenol + Acetate <=> Phenyl acetate + H2O R01242 3'-phosphoadenylylsulfate:phenol sulfotransferase; 3'-Phosphoadenylyl sulfate + Phenol <=> Adenosine 3',5'-bisphosphate + Aryl sulfate R01243 aryl-sulfate sulfohydrolase; Aryl sulfate + H2O <=> Phenol + Sulfate R01244 adenine aminohydrolase; Adenine + H2O <=> Hypoxanthine + Ammonia R01245 adenosine ribohydrolase; Adenosine + H2O <=> Adenine + D-Ribose R01246 L-proline:NAD+ 2-oxidoreductase; L-Proline + NAD+ <=> 1-Pyrroline-2-carboxylate + NADH + H+ R01248 L-proline:NAD+ 5-oxidoreductase; L-Proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H+ R01249 L-proline:NADP+ 2-oxidoreductase; L-Proline + NADP+ <=> 1-Pyrroline-2-carboxylate + NADPH + H+ R01251 L-proline:NADP+ 5-oxidoreductase; L-Proline + NADP+ <=> (S)-1-Pyrroline-5-carboxylate + NADPH + H+ R01252 L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating); L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2 R01253 L-proline:quinone oxidoreductase; L-Proline + Quinone <=> (S)-1-Pyrroline-5-carboxylate + Hydroquinone R01255 proline racemase; L-Proline <=> D-Proline R01256 (S)-malate:CoA ligase (ADP-forming); ATP + (S)-Malate + CoA <=> ADP + Orthophosphate + L-Malyl-CoA R01257 (S)-malate:FAD oxidoreductase; (S)-Malate + FAD <=> Oxaloacetate + FADH2 R01258 L-amino-aicd:NAD+ oxidoreductase (deaminating); L-Amino acid + NAD+ + H2O <=> 2-Oxo acid + Ammonia + NADH + H+ R01259 L-amino-acid:oxygen oxidoreductase (deaminating); L-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide R01260 L-amino acid,NADPH:oxygen oxidoreductase (N-hydroxylating); L-Amino acid + Oxygen + NADPH <=> N-Hydroxy-amino acid + NADP+ + H2O R01261 L-alanine:2-oxo-acid aminotransferase; L-Alanine + 2-Oxo acid <=> Pyruvate + L-Amino acid R01262 glutathione:L-amino-acid 5-glutamyltransferase; Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid R01263 N-acyl-L-amino-acid amidohydrolase; N-Acyl-L-amino acid + H2O <=> Carboxylate + L-Amino acid R01264 N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating); N-Methyl-L-amino acid + H2O + Oxygen <=> L-Amino acid + Formaldehyde + Hydrogen peroxide R01265 amino-acid racemase; L-Amino acid <=> D-Amino acid R01266 1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase; N4-(Acetyl-beta-D-glucosaminyl)asparagine + H2O <=> N-Acetyl-D-glucosamine + L-Asparagine R01267 L-asparagine hydro-lyase (3-cyanoalanine-forming); L-Asparagine <=> 3-Cyano-L-alanine + H2O R01268 nicotinamide amidohydrolase; Nicotinamide + H2O <=> Nicotinate + Ammonia R01269 S-adenosyl-L-methionine:nicotinamide N-methyltransferase; S-Adenosyl-L-methionine + Nicotinamide + H+ <=> S-Adenosyl-L-homocysteine + 1-Methylnicotinamide R01270 nicotinamide D-ribonucleotide phosphoribohydrolase; Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide + D-Ribose 5-phosphate R01271 nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase; Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate R01273 N-ribosylnicotinamide ribohydrolase; Nicotinamide-beta-riboside + H2O <=> Nicotinamide + D-Ribose R01274 palmitoyl-CoA hydrolase; Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid R01277 hexadecanal:NAD+ oxidoreductase (CoA-acylating); Hexadecanal + CoA + NAD+ <=> Palmitoyl-CoA + NADH + H+ R01278 hexadecanoyl-CoA:NADP+ trans-2-oxidoreductase; trans-hexadec-2-enoyl-CoA reductase; Palmitoyl-CoA + NADP+ <=> trans-Hexadec-2-enoyl-CoA + NADPH + H+ R01279 palmitoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Palmitoyl-CoA + FAD <=> trans-Hexadec-2-enoyl-CoA + FADH2 R01280 palmitate:CoA ligase (AMP-forming); ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate R01281 palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating); Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2 R01282 Palmitoyl-CoA + Acceptor <=> trans-Hexadec-2-enoyl-CoA + Reduced acceptor R01283 L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming); L-Homocysteine + H2O <=> Hydrogen sulfide + Ammonia + 2-Oxobutanoate R01286 L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming); L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate R01287 O-acetyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-acetyl-L-homoserine acetate-lyase (adding hydrogen sulfide); O-Acetyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Acetate R01288 O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide); O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate R01289 L-serine hydro-lyase (adding homocysteine); L-Serine + L-Homocysteine <=> Cystathionine + H2O R01290 L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming); L-Serine + L-Homocysteine <=> L-Cystathionine + H2O R01291 S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]; S-Ribosyl-L-homocysteine <=> (S)-4,5-Dihydroxypentane-2,3-dione + L-Homocysteine R01292 glutathione:homocystine oxidoreductase; L-Homocystine + 2 Glutathione <=> 2 L-Homocysteine + Glutathione disulfide R01293 4-hydroxybenzaldehyde:NAD+ oxidoreductase; 4-Hydroxybenzaldehyde + NAD+ + H2O <=> 4-Hydroxybenzoate + NADH + H+ R01294 4-hydroxybenzaldehyde:NADP+ oxidoreductase; 4-Hydroxybenzaldehyde + NADP+ + H2O <=> 4-Hydroxybenzoate + NADPH + H+ R01295 benzoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating); Benzoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Hydroxybenzoate + [Oxidized NADPH---hemoprotein reductase] + H2O R01296 4-hydroxybenzoate,NADH:oxygen oxidoreductase (3-hydroxylating); 4-Hydroxybenzoate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + NAD+ + H2O R01297 4-hydroxybenzoate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 4-Hydroxybenzoate + Oxygen + NADH + H+ <=> Hydroquinone + CO2 + NAD+ + H2O R01298 4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating); 4-Hydroxybenzoate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + NADP+ + H2O R01299 4-hydroxybenzoate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 4-Hydroxybenzoate + Oxygen + NADPH + H+ <=> Hydroquinone + CO2 + NADP+ + H2O R01300 4-hydroxybenzoate:CoA ligase (AMP-forming); ATP + 4-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 4-Hydroxybenzoyl-CoA R01301 4-hydroxybenzoyl-CoA hydrolase; 4-Hydroxybenzoyl-CoA + H2O <=> 4-Hydroxybenzoate + CoA R01302 chorismate pyruvate-lyase (4-hydroxybenzoate-forming); 4-Hydroxybenzoate + Pyruvate <=> Chorismate R01303 4-Hydroxybenzoate + Acceptor + H2O <=> 4-Hydroxybenzaldehyde + Reduced acceptor + Oxygen R01304 UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase; UDP-glucose + 4-Hydroxybenzoate <=> UDP + 4-(beta-D-Glucosyloxy)benzoate R01305 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving); 4-Hydroxyphenacyl alcohol + Oxygen <=> 4-Hydroxybenzoate + Formate R01306 4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating); 4-Methoxybenzoate + Reduced acceptor + Oxygen <=> 4-Hydroxybenzoate + Formaldehyde + Acceptor + H2O R01307 4-chlorobenzoate chlorohydrolase; 4-Chlorobenzoate + H2O <=> 4-Hydroxybenzoate + Cl- + H+ R01308 4-Hydroxybenzoate + Acetate + NADH + H+ <=> 4-Coumarate + 2 H2O + NAD+ R01309 phosphatidylcholine acylhydrolase; Phosphatidylcholine + 2 H2O <=> sn-Glycero-3-phosphocholine + 2 Fatty acid R01310 phosphatidylcholine phosphatidohydrolase; Phosphatidylcholine + H2O <=> Phosphatidate + Choline R01312 phosphatidylcholine cholinephosphohydrolase; Phosphatidylcholine + H2O <=> 1,2-Diacyl-sn-glycerol + Choline phosphate R01313 phosphatidylcholine 2-acylhydrolase; Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate R01314 phosphatidylcholine 1-acylhydrolase; Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + Carboxylate R01315 phosphatidylcholine 2-acylhydrolase; Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid R01316 phosphatidylcholine 1-acylhydrolase; Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + Fatty acid R01317 phosphatidylcholine 2-acylhydrolase; Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate R01318 acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase; Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine R01319 acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase; Acyl-CoA + 2-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine R01320 S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine R01321 CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase; CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine R01322 citrate:CoA ligase (ADP-forming); ATP + Citrate + CoA <=> ADP + Orthophosphate + (3S)-Citryl-CoA R01323 acetyl-CoA:citrate CoA-transferase; Acetyl-CoA + Citrate <=> Acetate + (3S)-Citryl-CoA R01324 citrate hydroxymutase; Citrate <=> Isocitrate R01325 citrate hydro-lyase (cis-aconitate-forming); Citrate <=> cis-Aconitate + H2O R01326 ATP:D-mannose 6-phosphotransferase; ATP + D-Mannose <=> ADP + D-Mannose 6-phosphate R01327 ITP:D-mannose 6-phosphotransferase; ITP + D-Mannose <=> IDP + D-Mannose 6-phosphate R01328 dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase; Dolichyl phosphate D-mannose + H2O <=> Dolichyl phosphate + D-Mannose R01329 epimelibiose galactohydrolase; Epimelibiose + H2O <=> D-Mannose + D-Galactose R01330 dATP:D-mannose 6-phosphotransferase; dATP + D-Mannose <=> dADP + D-Mannose 6-phosphate R01331 (1->2)-(1->3)-alpha-D-mannan mannohydrolase; (1->2)-(1->6)-alpha-D-mannan D-mannohydrolase; G10542 + H2O <=> D-Mannose + G10542 R01332 beta-D-mannan hydrolases; 1,4-beta-D-Mannan + (n-1) H2O <=> n D-Mannose R01333 glycolaldehyde:NAD+ oxidoreductase; Glycolaldehyde + NAD+ + H2O <=> Glycolate + NADH + H+ R01334 2-phosphoglycolate phosphohydrolase; 2-Phosphoglycolate + H2O <=> Glycolate + Orthophosphate R01335 5-hydroxy-2,4-dioxopentanoate glycolylhydrolase; Glycolate + Pyruvate <=> 5-Hydroxy-2,4-dioxopentanoate + H2O R01336 carboxymethyloxysuccinate glycolate-lyase (fumarate-forming); Carboxymethyloxysuccinate <=> Fumarate + Glycolate R01337 2-oxoaldehyde:NAD+ 2-oxidoreductase; 2-Oxoaldehyde + NAD+ + H2O <=> 2-Oxo acid + NADH + H+ R01338 2-oxoaldehyde:NADP+ oxidoreductase; 2-Oxoaldehyde + NADP+ + H2O <=> 2-Oxo acid + NADPH + H+ R01339 L-glutamate:2-oxo acid aminotransferase; 2-Oxo acid + L-Glutamate <=> alpha-Amino acid + 2-Oxoglutarate R01340 D-amino-acid:oxygen oxidoreductase (deaminating); D-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide R01341 (S)-2-hydroxy-acid:oxygen 2-oxidoreductase; (S)-2-Hydroxyacid + Oxygen <=> 2-Oxo acid + Hydrogen peroxide R01342 D-amino-acid:(acceptor) oxidoreductase (deaminating); alpha-Amino acid + H2O + Acceptor <=> 2-Oxo acid + Ammonia + Reduced acceptor R01343 L-ornithine:2-oxo-acid aminotransferase; L-Ornithine + 2-Oxo acid <=> L-Glutamate 5-semialdehyde + L-Amino acid R01344 D-alanine:2-oxo acid aminotransferase; D-Amino acid + Pyruvate <=> 2-Oxo acid + D-Alanine R01346 L-asparagine:2-oxo-acid aminotransferase; L-Asparagine + 2-Oxo acid <=> 2-Oxosuccinamate + L-Amino acid R01347 fatty acid,reduced rubredoxin:oxygen oxidoreductase (omega-hydroxylating); Fatty acid + Oxygen + 2 Reduced rubredoxin + 2 H+ <=> omega-Hydroxy fatty acid + 2 Oxidized rubredoxin + H2O R01348 fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); Fatty acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> omega-Hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O R01349 S-adenosyl-L-methionine:fatty-acid O-methyltransferase; S-Adenosyl-L-methionine + Fatty acid <=> S-Adenosyl-L-homocysteine + Fatty acid methyl ester R01350 glycerol acylhydrolase; Glycerol + Fatty acid <=> Triacylglycerol R01351 1-acylglycerol acylhydrolase; 1-Acylglycerol + H2O <=> Glycerol + Fatty acid R01352 2-acylglycerol acylhydrolase; 2-Acylglycerol + H2O <=> Glycerol + Fatty acid R01353 ATP:propanoate phosphotransferase; ATP + Propanoate <=> ADP + Propanoyl phosphate R01354 ATP:propanoate adenylyltransferase; ATP + Propanoate <=> Diphosphate + Propionyladenylate R01355 2,3-dimethylmalate pyruvate-lyase; (2R,3S)-2,3-Dimethylmalate <=> Propanoate + Pyruvate R01357 acetoacetate:CoA ligase (AMP-forming); ATP + Acetoacetate + CoA <=> AMP + Diphosphate + Acetoacetyl-CoA R01358 acetoacetyl-CoA hydrolase; Acetoacetyl-CoA + H2O <=> Acetoacetate + CoA R01359 acetoacetyl-CoA:acetate CoA-transferase; Acetoacetyl-CoA + Acetate <=> Acetoacetate + Acetyl-CoA R01360 (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming); (S)-3-Hydroxy-3-methylglutaryl-CoA <=> Acetyl-CoA + Acetoacetate R01361 (R)-3-hydroxybutanoate:NAD+ oxidoreductase; (R)-3-Hydroxybutanoate + NAD+ <=> Acetoacetate + NADH + H+ R01364 4-fumarylacetoacetate fumarylhydrolase; Acetoacetate + Fumarate <=> 4-Fumarylacetoacetate + H2O R01365 butanoyl-CoA:acetoacetate CoA-transferase; Butanoyl-CoA + Acetoacetate <=> Butanoic acid + Acetoacetyl-CoA R01366 acetoacetate carboxy-lyase (acetone-forming); Acetoacetate <=> Acetone + CO2 R01367 acetoacetate hydro-lyase (3-butynoate-forming); Acetoacetate <=> 3-Butynoate + H2O R01368 acyl-CoA:2-acylglycerol O-acyltransferase; Acyl-CoA + 2-Acylglycerol <=> CoA + Diacylglycerol R01369 triacylglycerol acylhydrolase; Triacylglycerol + H2O <=> Diacylglycerol + Carboxylate R01370 phenyllactate:NAD+ oxidoreductase; Phenyllactate + NAD+ <=> Phenylpyruvate + NADH + H+ R01371 phenyllactate:NADP+ oxidoreductase; Phenyllactate + NADP+ <=> Phenylpyruvate + NADPH + H+ R01372 phenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating); Phenylpyruvate + Oxygen <=> 2-Hydroxyphenylacetate + CO2 R01373 prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming); Prephenate <=> Phenylpyruvate + H2O + CO2 R01374 D-phenylalanine:quinone oxidoreductase (deaminating); D-Phenylalanine + H2O + Quinone <=> Phenylpyruvate + Ammonia + Hydroquinone R01375 L-glutamine:phenylpyruvate aminotransferase; L-Glutamine + Phenylpyruvate <=> 2-Oxoglutaramate + L-Phenylalanine R01376 L-tryptophan:phenylpyruvate aminotransferase; L-Tryptophan + Phenylpyruvate <=> Indolepyruvate + L-Phenylalanine R01377 phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming); Phenylpyruvate <=> Phenylacetaldehyde + CO2 R01378 phenylpyruvate keto-enol-isomerase; Phenylpyruvate <=> 2-Hydroxy-3-phenylpropenoate R01381 UTP:1-phospho-alpha-D-glucuronate uridylyltransferase; UTP + D-Glucuronate 1-phosphate <=> Diphosphate + UDP-glucuronate R01383 UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); UDP-glucuronate + ROH <=> UDP + beta-D-Glucuronoside R01384 UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming); UDP-glucuronate <=> UDP-D-xylose + CO2 R01385 UDP-glucuronate 4-epimerase; UDP-glucuronate <=> UDP-D-galacturonate R01386 UDP-D-glucuronate carboxy-lyase (UDP-D-apiose-forming); UDP-glucuronate <=> UDP-apiose + CO2 R01387 UDP-glucuronate 5'-epimerase; UDP-glucuronate <=> UDP-L-iduronate R01388 D-glycerate:NAD+ 2-oxidoreductase; D-Glycerate + NAD+ <=> Hydroxypyruvate + NADH + H+ R01390 Hydroxypyruvate + CO2 <=> Dihydroxyfumarate R01392 D-glycerate:NADP+ 2-oxidoreductase; D-Glycerate + NADP+ <=> Hydroxypyruvate + NADPH + H+ R01393 hydroxypyruvate carboxy-lyase (glycolaldehyde-forming); Hydroxypyruvate <=> Glycolaldehyde + CO2 R01394 hydroxypyruvate aldose-ketose-isomerase; Hydroxypyruvate <=> 2-Hydroxy-3-oxopropanoate R01395 ATP:carbamate phosphotransferase; ATP + Carbamate <=> ADP + Carbamoyl phosphate R01396 carbamoyl-phosphate:L-lysine carbamoyltransferase; Carbamoyl phosphate + L-Lysine <=> Orthophosphate + L-Homocitrulline R01397 carbamoyl-phosphate:L-aspartate carbamoyltransferase; Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate R01398 carbamoyl-phosphate:L-ornithine carbamoyltransferase; Carbamoyl phosphate + L-Ornithine <=> Orthophosphate + L-Citrulline R01399 carbamoyl-phosphate:putrescine carbamoyltransferase; Carbamoyl phosphate + Putrescine <=> Orthophosphate + N-Carbamoylputrescine R01400 Carbamoyl phosphate <=> Cyclic amidine R01401 methylthioadenosine methylthioribohydrolase; 5'-Methylthioadenosine + H2O <=> Adenine + 5-Methylthio-D-ribose R01402 S-methyl-5'-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase; 5'-Methylthioadenosine + Orthophosphate <=> Adenine + S-Methyl-5-thio-D-ribose 1-phosphate R01403 acyl-[acyl-carrier-protein]:NAD+ oxidoreductase; Acyl-[acyl-carrier protein] + NAD+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ R01404 acyl-[acyl-carrier protein]:NADP+ oxidoreductase; Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+ R01406 long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming); ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein] R01407 long-chain-fatty-acid:protein ligase (AMP-forming); ATP + Long-chain fatty acid + [Protein]-L-cysteine <=> AMP + Diphosphate + [Protein]-S-(long-chain-acyl)-L-cysteine R01408 formamide hydro-lyase (cyanide-forming); Formamide <=> Hydrogen cyanide + H2O R01409 cyanohydrin aldehyde-lyase (cyanide-forming); Cyanohydrin <=> Cyanide ion + Aldehyde R01410 Hydrogen cyanide + Acetaldehyde + Ammonia <=> alpha-Aminopropiononitrile + H2O R01411 5-methylcytosine aminohydrolase; 5-Methylcytosine + H2O <=> Thymine + Ammonia R01412 thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating); Thymine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxymethyluracil + Succinate + CO2 R01413 thymine:acceptor oxidoreductase; Thymine + Acceptor + H2O <=> 5-Methylbarbiturate + Reduced acceptor R01414 5,6-dihydrothymine:NAD+ oxidoreductase; 5,6-Dihydrothymine + NAD+ <=> Thymine + NADH + H+ R01415 5,6-dihydrothymine:NADP+ oxidoreductase; (R)-5,6-Dihydrothymine + NADP+ <=> Thymine + NADPH + H+ R01416 agmatine iminohydrolase; Agmatine + H2O <=> N-Carbamoylputrescine + Ammonia R01417 ATP:agmatine N4-phosphotransferase; ATP + Agmatine <=> ADP + Phosphoagmatine R01418 1,4-diguanidinobutane amidinohydrolase; Agmatine + Urea <=> Arcaine + H2O R01419 benzaldehyde:NAD+ oxidoreductase; Benzaldehyde + NAD+ + H2O <=> Benzoate + NADH + H+ R01420 benzaldehyde:NADP+ oxidoreductase; Benzaldehyde + NADP+ + H2O <=> Benzoate + NADPH + H+ R01421 benzoyl phosphate phosphohydrolase; Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate R01422 benzoate:CoA ligase (AMP-forming); ATP + Benzoate + CoA <=> AMP + Diphosphate + Benzoyl-CoA R01423 5'-benzoylphosphoadenosine benzoylhydrolase; 5'-Benzoylphosphoadenosine + H2O <=> AMP + Benzoate R01424 N-benzoylglycine amidohydrolase; Hippurate + H2O <=> Benzoate + Glycine R01425 benzoylagmatine amidohydrolase; Benzoylagmatine + H2O <=> Benzoate + Agmatine R01426 Benzoate + Acetate + NADH + H+ <=> trans-Cinnamate + 2 H2O + NAD+ R01427 Benzoate <=> 3-Hydroxybenzoate R01429 D-xylose:NAD+ 1-oxidoreductase; D-Xylose + NAD+ <=> D-Xylonolactone + NADH + H+ R01430 D-xylose:NADP+ 1-oxidoreductase; D-Xylose + NADP+ <=> D-Xylonolactone + NADPH + H+ R01431 xylitol:NADP+ oxidoreductase; Xylitol + NADP+ <=> D-Xylose + NADPH + H+ R01432 D-xylose aldose-ketose-isomerase; D-Xylose <=> D-Xylulose R01433 D-xylose xylohydrolase; D-Xylose + 1,4-beta-D-Xylan <=> 1,4-beta-D-Xylan + H2O R01434 L-valine:NAD+ oxidoreductase(deaminating); L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+ R01437 L-valine carboxy-lyase (2-methylpropanamine-forming); L-Valine <=> 2-Methylpropanamine + CO2 R01440 D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase; D-Xylulose 5-phosphate + Formaldehyde <=> D-Glyceraldehyde 3-phosphate + Glycerone R01441 ATP:cellobiose 6-phosphotransferase; ATP + Cellobiose <=> ADP + 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose R01442 cellobiose:oxygen 1-oxidoreductase; Cellobiose + Oxygen <=> Cellobiono-1,5-lactone + Hydrogen peroxide R01443 cellobiose:(acceptor) 1-oxidoreductase; Cellobiose + Acceptor <=> Cellobiono-1,5-lactone + Reduced acceptor R01444 cellotriose glucohydrolase; Cellotriose + H2O <=> Cellobiose + D-Glucose R01445 cellobiose 2-epimerase; Cellobiose <=> 4-O-beta-D-Glucopyranosyl-D-mannose R01446 (S)-lactaldehyde:NAD+ oxidoreductase; (S)-Lactaldehyde + NAD+ + H2O <=> (S)-Lactate + NADH + H+ R01447 (S)-lactate:oxaloacetate oxidoreductase; (S)-Lactate + Oxaloacetate <=> (S)-Malate + Pyruvate R01448 (R)-2-O-sulfolactate 2-sulfohydrolase; (R)-2-O-Sulfolactate + H2O <=> (R)-Lactate + Sulfate R01449 lactoyl-CoA:propanoate CoA-transferase; Lactoyl-CoA + Propanoate <=> (S)-Lactate + Propanoyl-CoA R01450 lactate racemase; (S)-Lactate <=> (R)-Lactate R01451 cholesterol:NAD+ delta7-oxidoreductase; Cholesterol + NAD+ <=> 7-Dehydrocholesterol + NADH + H+ R01452 cholesterol,NADPH:oxygen oxidoreductase (5alpha,6alpha-epoxidizing); Cholesterol + Oxygen + NADPH + H+ <=> Cholesterol-5alpha,6alpha-epoxide + NADP+ + H2O R01453 cholesterol,NADPH:oxygen oxidoreductase (5beta,6beta-epoxidizing); Cholesterol + Oxygen + NADPH + H+ <=> Cholesterol-5beta,6beta-epoxide + NADP+ + H2O R01454 cholesterol:oxygen oxidoreductase (side-chain-cleaving); Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 20alpha-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin R01456 cholesterol:NADP+ delta7-oxidoreductase; Cholesterol + NADP+ <=> 7-Dehydrocholesterol + NADPH + H+ R01457 cholesterol:NADP+ Delta24-oxidoreductase; Cholesterol + NADP+ <=> Desmosterol + H+ + NADPH R01459 cholesterol:oxygen oxidoreductase; Cholesterol + Oxygen <=> Cholest-4-en-3-one + Hydrogen peroxide R01460 cholesteryl-beta-D-glucoside glucohydrolase; Cholesteryl-beta-D-glucoside + H2O <=> Cholesterol + D-Glucose R01461 acyl-CoA:cholesterol O-acyltransferase; Acyl-CoA + Cholesterol <=> CoA + Cholesterol ester R01462 cholesterol ester acylhydrolase; Cholesterol ester + H2O <=> Cholesterol + Fatty acid R01463 cholesterol,NADPH-hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating); Cholesterol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R01465 L-threonine:NAD+ oxidoreductase; L-Threonine + NAD+ <=> L-2-Amino-3-oxobutanoic acid + NADH + H+ R01466 O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate R01467 threonine racemase; L-Threonine <=> D-Threonine R01468 ATP:ethanolamine O-phosphotransferase; ATP + Ethanolamine <=> ADP + Ethanolamine phosphate R01469 ethanolamine:oxygen oxidoreductase (deaminating); Ethanolamine + H2O + Oxygen <=> Glycolaldehyde + Ammonia + Hydrogen peroxide R01470 sn-glycero-3-phosphoethanolamine glycerophosphohydrolase; sn-Glycero-3-phosphoethanolamine + H2O <=> Ethanolamine + sn-Glycerol 3-phosphate R01471 UTP:alpha-D-xylose-1-phosphate uridylyltransferase; UTP + alpha-D-Xylose 1-phosphate <=> Diphosphate + UDP-D-xylose R01472 UDP-D-xylose:dolichyl-phosphate D-xylosyltrtansferase; UDP-D-xylose + Dolichyl phosphate <=> UDP + Dolichyl D-xylosyl phosphate R01473 UDP-L-arabinose 4-epimerase; UDP-L-arabinose <=> UDP-D-xylose R01474 UDP-D-xylose <=> Pentosan + UDP R01476 ATP:D-glucuronate 1-phosphotransferase; ATP + D-Glucuronate <=> ADP + D-Glucuronate 1-phosphate R01478 beta-D-glucuronoside glucuronosohydrolase; H2O + beta-D-Glucuronoside <=> D-Glucuronate + Alcohol R01480 alpha-D-glucosiduronate glucuronohydrolase; alpha-D-Glucuronoside + H2O <=> Alcohol + D-Glucuronate R01481 L-gulonate:NADP+ 6-oxidoreductase; L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+ R01482 D-glucuronate aldose-ketose-isomerase; D-Glucuronate <=> D-Fructuronate R01483 D-glucuronolactone lactonohydrolase; D-Glucuronolactone + H2O <=> D-Glucuronate R01484 D-glucurono-6,2-lactone lactonohydrolase; D-Glucurono-6,2-lactone + H2O <=> D-Glucuronate R01485 L-asparagine:hydroxylamine gamma-aspartyltransferase; L-Asparagine + Hydroxylamine <=> Ammonia + beta-L-Aspartylhydroxamate R01486 aromatic aldehyde:NAD+ oxidoreductase; Aromatic aldehyde + NAD+ + H2O <=> Aromatic acid + NADH + H+ R01487 aromatic alcohol:NAD+ oxidoreductase; Aromatic primary alcohol + NAD+ <=> Aromatic aldehyde + NADH + H+ R01488 aromatic alcohol:NADP+ oxidoreductase; Aromatic primary alcohol + NADP+ <=> Aromatic aldehyde + NADPH + H+ R01489 aromatic aldehyde:oxygen oxidoreductase; Aromatic aldehyde + Oxygen + H2O <=> Aromatic acid + Hydrogen peroxide R01490 aromatic aldehyde:NADP+ oxidoreductase (ATP-forming); Aromatic aldehyde + AMP + Diphosphate + NADP+ <=> Aromatic acid + NADPH + ATP + H+ R01491 aromatic alcohol:oxygen oxidoreductase; Aromatic primary alcohol + Oxygen <=> Aromatic aldehyde + Hydrogen peroxide R01492 ATP:cob(I)alamin Co-beta-adenosyltransferase; ATP + Cob(I)alamin <=> Triphosphate + Cobamide coenzyme R01493 N-acylsphingosine amidohydrolase; N-Acylsphingosine + H2O <=> Carboxylate + Sphingosine R01494 N-acylsphingosine amidohydrolase; N-Acylsphingosine + H2O <=> Fatty acid + Sphingosine R01495 ATP:ceramide 1-phosphotransferase; ATP + N-Acylsphingosine <=> ADP + Ceramide 1-phosphate R01496 acyl-CoA:sphingosine N-acyltransferase; Acyl-CoA + Sphingosine <=> CoA + N-Acylsphingosine R01497 UDP-glucose:N-acylsphingosine D-glucosyltransferase; UDP-glucose + N-Acylsphingosine <=> UDP + Glucosylceramide R01498 D-glucosyl-N-acylsphingosine glucohydrolase; Glucosylceramide + H2O <=> D-Glucose + N-Acylsphingosine R01500 UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase; UDP-alpha-D-galactose + N-Acylsphingosine <=> UDP + Galactosylceramide R01503 CDP-ethanolamine:ceramide phosphoethanolaminyltransferase; CDP-ethanolamine + N-Acylsphingosine <=> CMP + Ceramide phosphoethanolamine R01504 ATP:2,3-dihydroxybenzoate adenylyltransferase; ATP + 2,3-Dihydroxybenzoate <=> Diphosphate + (2,3-Dihydroxybenzoyl)adenylate R01505 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase; (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate + NAD+ <=> 2,3-Dihydroxybenzoate + NADH + H+ R01506 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing); 2,3-Dihydroxybenzoate + Oxygen <=> 2-Carboxy-cis,cis-muconate R01507 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing); 2,3-Dihydroxybenzoate + Oxygen <=> 3-Carboxy-2-hydroxymuconate semialdehyde R01508 3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreduxtase (2-hydroxylating); 3-Hydroxybenzoate + Reduced acceptor + Oxygen <=> 2,3-Dihydroxybenzoate + Acceptor + H2O R01511 D-glycerate-3-phosphate phosphohydrolase; 3-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate R01512 ATP:3-phospho-D-glycerate 1-phosphotransferase; ATP + 3-Phospho-D-glycerate <=> ADP + 3-Phospho-D-glyceroyl phosphate R01513 3-phospho-D-glycerate:NAD+ 2-oxidoreductase; 3-Phospho-D-glycerate + NAD+ <=> 3-Phosphonooxypyruvate + NADH + H+ R01514 ATP:(R)-glycerate 3-phosphotransferase; ATP + D-Glycerate <=> ADP + 3-Phospho-D-glycerate R01515 3-phospho-D-glyceroyl phosphate phosphohydrolase; 3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate R01516 2,3-bisphospho-D-glycerate 2-phosphohydrolase; 2,3-Bisphospho-D-glycerate + Protein histidine <=> 3-Phospho-D-glycerate + Protein N(tau)-phospho-L-histidine R01517 GTP:3-phospho-D-glycerate 1-phosphotransferase; GTP + 3-Phospho-D-glycerate <=> GDP + 3-Phospho-D-glyceroyl phosphate R01518 D-phosphoglycerate 2,3-phosphomutase; 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate R01519 D-glucono-1,5-lactone lactonohydrolase; D-Glucono-1,5-lactone + H2O <=> D-Gluconic acid R01520 beta-D-glucose:NAD+ 1-oxoreductase; beta-D-Glucose + NAD+ <=> D-Glucono-1,5-lactone + NADH + H+ R01521 beta-D-glucose:NADP+ 1-oxoreductase; beta-D-Glucose + NADP+ <=> D-Glucono-1,5-lactone + NADPH + H+ R01522 beta-D-glucose:oxygen 1-oxidoreductase; beta-D-Glucose + Oxygen <=> D-Glucono-1,5-lactone + Hydrogen peroxide R01523 ATP:D-ribulose-5-phosphate 1-phosphotransferase; ATP + D-Ribulose 5-phosphate <=> ADP + D-Ribulose 1,5-bisphosphate R01524 D-ribitol-5-phosphate:NAD+ 2-oxidoreductase; D-Ribitol 5-phosphate + NAD+ <=> D-Ribulose 5-phosphate + NADH + H+ R01525 D-ribitol-5-phosphate:NADP+ 2-oxidoreductase; D-Ribitol 5-phosphate + NADP+ <=> D-Ribulose 5-phosphate + NADPH + H+ R01526 ATP:D-ribulose 5-phosphotransferase; ATP + D-Ribulose <=> ADP + D-Ribulose 5-phosphate R01528 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating); 6-Phospho-D-gluconate + NADP+ <=> D-Ribulose 5-phosphate + CO2 + NADPH + H+ R01529 D-ribulose-5-phosphate 3-epimerase; D-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate R01530 D-arabinose-5-phosphate aldose-ketose-isomerase; D-Arabinose 5-phosphate <=> D-Ribulose 5-phosphate R01532 nucleoside-triphosphate diphosphohydrolase; Nucleoside triphosphate + H2O <=> Nucleotide + Diphosphate R01533 diisopropyl-fluorophosphate fluorohydrolase; Isoflurophate + H2O <=> Diisopropyl phosphate + Hydrofluoric acid R01535 UDP-alpha-D-galactose:undecaprenyl-phosphate galactose phosphotransferase; UDP-alpha-D-galactose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Galactosyl-diphosphoundecaprenol R01537 UDP-N-acetyl-D-galactosamine <=> Glycolipid R01538 D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming); D-Gluconic acid <=> 2-Dehydro-3-deoxy-D-gluconate + H2O R01540 D-altronate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming); D-Altronate <=> 2-Dehydro-3-deoxy-D-gluconate + H2O R01541 ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase; ATP + 2-Dehydro-3-deoxy-D-gluconate <=> ADP + 2-Dehydro-3-deoxy-6-phospho-D-gluconate R01542 2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase; 2-Dehydro-3-deoxy-D-gluconate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+ R01543 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase; 2-Dehydro-3-deoxy-D-gluconate + NADP+ <=> (4S,5S)-4,5-Dihydroxy-2,6-dioxohexanoate + NADPH + H+ R01544 2-amino-2-deoxy-D-gluconate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming); 2-Amino-2-deoxy-D-gluconate <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia R01547 ATP:dAMP phosphotransferase; ATP + dAMP <=> ADP + dADP R01550 propan-2-ol:NADP+ oxidoreductase; Acetone + NADPH + H+ <=> Propan-2-ol + NADP+ R01553 acetone-cyanohydrin acetone-lyase (cyanide-forming); Acetone cyanohydrin <=> Hydrogen cyanide + Acetone R01555 maltose:phosphate 1-beta-D-glucosyltransferase; Maltose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R01556 acetyl-CoA:maltose O-acetyltransferase; Acetyl-CoA + Maltose <=> CoA + Acetyl-maltose R01557 maltose alpha-D-glucosylmutase; Maltose <=> alpha,alpha-Trehalose R01558 oxalate:CoA ligase (AMP-forming); ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA R01559 succinyl-CoA:oxalate CoA-transferase; Succinyl-CoA + Oxalate <=> Succinate + Oxalyl-CoA R01560 adenosine aminohydrolase; Adenosine + H2O <=> Inosine + Ammonia R01561 adenosine:phosphate alpha-D-ribosyltransferase; Adenosine + Orthophosphate <=> Adenine + alpha-D-Ribose 1-phosphate R01562 adenosine 3'-phosphate phosphohydrolase; 3'-AMP + H2O <=> Adenosine + Orthophosphate R01563 N-carbamoylsarcosine amidohydrolase; N-Carbamoylsarcosine + H2O <=> Sarcosine + CO2 + Ammonia R01564 N,N-dimethylglycine,5,6,7,8-tetrahydrofolate:oxygen oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming); N,N-Dimethylglycine + Tetrahydrofolate + Oxygen <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Hydrogen peroxide R01565 N,N-dimethylglycine,5,6,7,8-tetrahydrofolate:electron-transferflavoprotein oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming); N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein R01566 creatine amidinohydrolase; Creatine + H2O <=> Sarcosine + Urea R01567 ATP:thymidine 5'-phosphotransferase; ATP + Thymidine <=> ADP + dTMP R01568 ADP:thymidine 5'-phosphotransferase; ADP + Thymidine <=> AMP + dTMP R01569 thymidylate 5'-phosphohydrolase; dTMP + H2O <=> Thymidine + Orthophosphate R01570 thymidine:phosphate deoxy-alpha-D-ribosyltransferase; Thymidine + Orthophosphate <=> Thymine + 2-Deoxy-D-ribose 1-phosphate R01571 AMP:thymidine 5'-phosphotransferase; AMP + Thymidine <=> Adenosine + dTMP R01573 ATP:D-arabinose 5-phosphotransferase; ATP + D-Arabinose <=> ADP + D-Arabinose 5-phosphate R01574 D-arabinose:NAD+ 1-oxidoreductase; D-Arabinose + NAD+ <=> D-Arabinono-1,4-lactone + NADH + H+ R01575 D-arabinose:NADP+ 1-oxidoreductase; D-Arabinose + NADP+ <=> D-Arabinono-1,4-lactone + NADPH + H+ R01576 3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming); 3-Deoxy-D-manno-octulosonate <=> Pyruvate + D-Arabinose R01577 D-arabinose aldose-ketose-isomerase; D-Arabinose <=> D-Ribulose R01578 D-Glutamate + Peptide <=> D-Glutamyl-peptide R01579 D-glutamine amidohydrolase; D-Glutamine + H2O <=> D-Glutamate + Ammonia R01580 pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming); Pyridoxamine phosphate + 2-Oxoglutarate <=> Pyridoxal phosphate + D-Glutamate R01581 N-acyl-D-glutamate amidohydrolase; N-Acyl-D-glutamate + H2O <=> Carboxylate + D-Glutamate R01582 D-phenylalanine:2-oxoglutarate aminotransferase; D-Phenylalanine + 2-Oxoglutarate <=> Phenylpyruvate + D-Glutamate R01583 D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming); D-Glutamate <=> 5-Oxo-D-proline + H2O R01584 N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating); N-Methyl-L-alanine + H2O + NADP+ <=> Pyruvate + Methylamine + NADPH + H+ R01585 L-glutamate:methylamine ligase (ADP-forming); ATP + L-Glutamate + Methylamine <=> ADP + Orthophosphate + N5-Methyl-L-glutamine R01586 L-glutamate:methylamine 1,3-dicarboxypropyltransferase (N-methyl-L-glutamate-forming); Methylamine + L-Glutamate <=> Ammonia + N-Methyl-L-glutamate R01587 N-methyl-2-oxoglutaramate methylamidohydrolase; N-Methyl-2-oxoglutaramate + H2O <=> Methylamine + 2-Oxoglutarate R01588 dimethylamine:electron-transferring flavoprotein oxidoreductase; Dimethylamine + H2O + Electron-transferring flavoprotein <=> Methylamine + Formaldehyde + Reduced electron-transferring flavoprotein R01589 methylguanidine amidinohydrolase; Methylguanidine + H2O <=> Methylamine + Urea R01590 arachidonate:oxygen oxidoreductase; Arachidonate + 2 Oxygen <=> Prostaglandin G2 R01593 arachidonate:oxygen 15-oxidoreductase; Arachidonate + Oxygen <=> 15(S)-HPETE R01594 arachidonate:oxygen 8-oxidoreductase; Arachidonate + Oxygen <=> 8(R)-HPETE R01595 arachidonate:oxygen 5-oxidoreductase; Arachidonate + Oxygen <=> 5(S)-HPETE R01596 arachidonate:oxygen 12-oxidoreductase; Arachidonate + Oxygen <=> 12(S)-HPETE R01598 arachidonate:CoA ligase (AMP-forming); ATP + Arachidonate + CoA <=> AMP + Diphosphate + Arachidonyl-CoA R01599 arachidonate,reduced acceptor:oxygen oxidoreductase; Arachidonate + Reduced acceptor + 2 Oxygen <=> Prostaglandin H2 + Acceptor + H2O R01600 ATP:beta-D-glucose 6-phosphotransferase; ATP + beta-D-Glucose <=> ADP + beta-D-Glucose 6-phosphate R01602 D-glucose 1-epimerase; alpha-D-Glucose <=> beta-D-Glucose R01604 3-oxopropanoate:NAD+ oxidoreductase; 3-Oxopropanoate + NAD+ + H2O <=> Malonate + NADH + H+ R01607 3-oxopropanoate:NADP+ oxidoreductase; 3-Oxopropanoate + NADP+ + H2O <=> Malonate + NADPH + H+ R01608 3-hydroxypropanoate:NAD+ oxidoreductase; 3-Hydroxypropanoate + NAD+ <=> 3-Oxopropanoate + NADH + H+ R01609 3-aci-nitropropanoate:oxygen oxidoreductase; 3-Oxopropanoate + Nitrite + Hydrogen peroxide <=> 3-aci-Nitropropanoate + Oxygen + H2O R01611 3-oxopropanoate hydro-lyase; 3-Oxopropanoate <=> Propynoate + H2O R01613 malonyl-CoA:4-coumaroyl-CoA malonyltransferase(cyclizing); p-Coumaroyl-CoA + 3 Malonyl-CoA <=> Naringenin chalcone + 4 CoA + 3 CO2 R01614 malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing); 3 Malonyl-CoA + p-Coumaroyl-CoA <=> 4 CoA + Resveratrol + 4 CO2 R01615 4-hydroxycinnamyl aldehyde:NADP+ oxidoreductase (CoA-hydroxycinnamoylating); 4-Hydroxycinnamyl aldehyde + CoA + NADP+ <=> p-Coumaroyl-CoA + NADPH + H+ R01616 4-coumarate:CoA ligase (AMP-forming); ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA R01617 4-coumaroyl-CoA:agmatine N4-coumaroyltransferase; p-Coumaroyl-CoA + Agmatine <=> p-Coumaroylagmatine + CoA R01618 APS:ATP adenylyltransferase; Adenylyl sulfate + ATP <=> Sulfate + P1,P4-Bis(5'-adenosyl)tetraphosphate R01619 adenylyl-sulfate:ammonia adenylyltransferase; Adenylyl sulfate + Ammonia <=> Adenosine 5'-phosphoramidate + Sulfate R01620 acetyl-phosphate:L-lysine N6-acetyltransferase; Acetyl phosphate + L-Lysine <=> Orthophosphate + N6-Acetyl-L-lysine R01621 D-xylulose 5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming); D-Xylulose 5-phosphate + Orthophosphate <=> Acetyl phosphate + D-Glyceraldehyde 3-phosphate + H2O R01623 [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase; Acyl-carrier protein + H2O <=> Pantetheine 4'-phosphate + Apo-[acyl-carrier protein] R01624 acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase; Acetyl-CoA + Acyl-carrier protein <=> CoA + Acetyl-[acyl-carrier protein] R01625 CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase; CoA + Apo-[acyl-carrier protein] <=> Adenosine 3',5'-bisphosphate + Acyl-carrier protein R01626 malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase; Malonyl-CoA + Acyl-carrier protein <=> CoA + Malonyl-[acyl-carrier protein] R01627 3-dehydroshikimate hydro-lyase; 3-Dehydroshikimate <=> 3,4-Dihydroxybenzoate + H2O R01628 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating); 3-Hydroxybenzoate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + NADP+ + H2O R01629 protocatechuate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 3,4-Dihydroxybenzoate + Oxygen + NADH + H+ <=> Benzene-1,2,4-triol + CO2 + NAD+ + H2O R01630 protocatechuate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 3,4-Dihydroxybenzoate + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + CO2 + NADP+ + H2O R01631 protocatechuate:oxygen 3,4-oxidoreductase (decyclizing); 3,4-Dihydroxybenzoate + Oxygen <=> 3-Carboxy-cis,cis-muconate R01632 protocatechuate:oxygen 4,5-oxidoreductase (decyclizing); 3,4-Dihydroxybenzoate + Oxygen <=> 4-Carboxy-2-hydroxymuconate semialdehyde R01633 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase; (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ <=> 3,4-Dihydroxybenzoate + CO2 + NADH + H+ R01634 3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming); 3,4-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2 R01635 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming); 4,5-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2 R01636 4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming); 4-Sulfobenzoate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + Sulfite + NAD+ R01637 3,4-Dihydroxybenzoate <=> Gallate R01639 ATP:D-xylulose 5-phosphotransferase; ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate R01641 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Ribose 5-phosphate + D-Xylulose 5-phosphate R01644 4-hydroxybutanoate:NAD+ oxidoreductase; 4-Hydroxybutanoic acid + NAD+ <=> Succinate semialdehyde + NADH + H+ R01645 4-hydroxy-2-oxo-heptandioate succinate-semialdehyde-lyase (pyruvate-forming); 4-Hydroxy-2-oxo-heptanedioate <=> Succinate semialdehyde + Pyruvate R01647 2,4-dihydroxyhept-2-enedioate succinate-semialdehyde-lyase (pyruvate-forming); Succinate semialdehyde + Pyruvate <=> 2,4-Dihydroxyhept-2-enedioate R01648 4-aminobutanoate:2-oxoglutarate aminotransferase; 4-Aminobutanoate + 2-Oxoglutarate <=> Succinate semialdehyde + L-Glutamate R01649 2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating); 2-(Acetamidomethylene)succinate + 2 H2O <=> Acetate + Succinate semialdehyde + Ammonia + CO2 R01650 Succinate semialdehyde + Hydrogen cyanide + Ammonia <=> gamma-Amino-gamma-cyanobutanoate + H2O R01651 4-methyl-2-oxopentanoate:NAD+ oxidoreductase (CoA-mehtylpropanoylating); 4-Methyl-2-oxopentanoate + CoA + NAD+ <=> 3-Methylbutanoyl-CoA + CO2 + NADH + H+ R01652 4-Methyl-2-oxopentanoate + CO2 <=> (2S)-2-Isopropyl-3-oxosuccinate R01654 10-formyltetrahydrofolate:L-glutamate ligase (ADP-forming); ATP + 10-Formyltetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + (6R)-10-Formyltetrahydropteroyldiglutamate R01655 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing); 5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H+ R01657 dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase; Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan R01658 dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase; Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranyl diphosphate R01659 dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase; Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Neryl diphosphate R01660 3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase; 3-Phospho-D-glyceroyl phosphate + D-Glucose 1-phosphate <=> 3-Phospho-D-glycerate + alpha-D-Glucose 1,6-bisphosphate R01662 3-phospho-D-glycerate 1,2-phosphomutase; 3-Phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate R01663 dCMP aminohydrolase; dCMP + H2O <=> dUMP + Ammonia R01664 2'-deoxycytidine 5'-monophosphate phosphohydrolase; dCMP + H2O <=> Deoxycytidine + Orthophosphate R01665 ATP:dCMP phosphotransferase; ATP + dCMP <=> ADP + dCDP R01666 ATP:deoxycitidine 5'-phosphotransferase; ATP + Deoxycytidine <=> ADP + dCMP R01667 dCDP nucleotidohydrolase; dCDP + H2O <=> dCMP + Orthophosphate R01668 dCTP nucleotidohydrolase; deoxycytidine 5'-triphosphate diphosphohydrolase; dCTP + H2O <=> dCMP + Diphosphate R01669 5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase; 5,10-Methylenetetrahydrofolate + H2O + dCMP <=> Tetrahydrofolate + 5-Hydroxymethyldeoxycytidylate R01670 5,10-methylenetetrahydrofolate:dCMP C-methyltransferase; 5,10-Methylenetetrahydrofolate + dCMP <=> Dihydrofolate + Deoxy-5-methylcytidylate R01676 guanine aminohydrolase; Guanine + H2O <=> Xanthine + Ammonia R01677 guanosine ribohydrolase; Guanosine + H2O <=> Guanine + D-Ribose R01678 lactose galactohydrolase; Lactose + H2O <=> alpha-D-Glucose + D-Galactose R01680 lactose:(acceptor) 3-oxidoreductase; Lactose + Acceptor <=> 3-Ketolactose + Reduced acceptor R01682 3-sulfo-L-alanine carboxy-lyase (taurine-forming); L-Cysteate <=> Taurine + CO2 R01683 tauropine:NAD+ oxidoreductase (taurine-forming); Tauropine + NAD+ + H2O <=> Taurine + Pyruvate + NADH + H+ R01684 taurine:2-oxoglutarate aminotransferase; Taurine + 2-Oxoglutarate <=> Sulfoacetaldehyde + L-Glutamate R01685 taurine:ferricytochrome-c oxidoreductase (deaminating); Taurine + H2O + 2 Ferricytochrome c <=> Sulfoacetaldehyde + Ammonia + 2 Ferrocytochrome c + 2 H+ R01686 L-arginine:taurine amidinotransferase; Taurine + L-Arginine <=> Taurocyamine + L-Ornithine R01687 (5-L-glutamyl)-peptide:taurine 5-glutamyltransferase; (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine R01688 ATP:butanoate 1-phosphotransferase; ATP + Butanoic acid <=> ADP + Butanoylphosphate R01689 butanoate:NAD+ delta2-oxidoreductase; Butanoic acid + NAD+ <=> 2-Butenoate + NADH + H+ R01690 5'-butyrylphosphoinosine butyrylhydrolase; 5'-Butyrylphosphoinosine + H2O <=> IMP + Butanoic acid R01694 L-sorbose:NADP+ 5-oxidoreductase; L-Sorbose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+ R01695 L-sorbose:oxygen 5-oxidoreductase; L-Sorbose + Oxygen <=> 5-Dehydro-D-fructose + Hydrogen peroxide R01696 L-sorbose:acceptor 5-oxidoreductase; L-Sorbose + Acceptor <=> 5-Dehydro-D-fructose + Reduced acceptor R01697 D-sorbitol:(acceptor) 1-oxidoreductase; D-Sorbitol + Acceptor <=> L-Sorbose + Reduced acceptor R01698 dihydrolipoamide:NAD+ oxidoreductase; Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+ R01699 pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating); Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2 R01700 2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating); 2-Oxoglutarate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2 R01701 3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating); 3-Methyl-2-oxobutanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 R01702 4-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating); 4-Methyl-2-oxopentanoate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + CO2 R01703 hexadecanoate:hydrogen-peroxide oxidoreductase; Hexadecanoic acid + 2 Hydrogen peroxide <=> Pentadecanal + CO2 + 3 H2O R01704 palmitaldehyde:NAD+ oxidoreductase; Hexadecanal + NAD+ + H2O <=> Hexadecanoic acid + NADH + H+ R01705 palmitoyl-protein hydrolase; Hexadecanoic acid + Protein <=> Palmitoyl-protein + H2O R01706 hexadecanoyl-[acyl-carrier protein] hydrolase; Hexadecanoyl-[acp] + H2O <=> Acyl-carrier protein + Hexadecanoic acid R01707 pyridoxal:NAD+ 4-oxidoreductase; Pyridoxal + NAD+ <=> 4-Pyridoxolactone + NADH + H+ R01708 pyridoxine:NADP+ 4-oxidoreductase; Pyridoxine + NADP+ <=> Pyridoxal + NADPH + H+ R01709 pyridoxal:oxygen 4-oxidoreductase; Pyridoxal + Oxygen + H2O <=> 4-Pyridoxate + Hydrogen peroxide R01710 pyridoxamine:oxygen oxidoreductase (deaminating); Pyridoxamine + H2O + Oxygen <=> Pyridoxal + Ammonia + Hydrogen peroxide R01711 pyridoxine:oxygen oxidoreductase (deaminating); Pyridoxine + Oxygen <=> Pyridoxal + Hydrogen peroxide R01712 pyridoxamine:pyruvate aminotransferase; Pyridoxamine + Pyruvate <=> Pyridoxal + L-Alanine R01713 pyridoxamine:oxaloacetate aminotransferase; Pyridoxamine + Oxaloacetate <=> Pyridoxal + L-Aspartate R01714 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming); 5-O-(1-Carboxyvinyl)-3-phosphoshikimate <=> Chorismate + Orthophosphate R01715 chorismate pyruvatemutase; Chorismate <=> Prephenate R01716 chorismate:L-glutamine aminotransferase; Chorismate + L-Glutamine <=> 4-Amino-4-deoxychorismate + L-Glutamate R01717 chorismate hydroxymutase; Chorismate <=> Isochorismate R01718 isomaltose 6-alpha-D-glucanohydrolase; Isomaltose + H2O <=> alpha-D-Glucose + D-Glucose R01720 nicotinate:NADP+ 6-oxidoreductase (hydroxylating); Nicotinate + NADP+ + H2O <=> 6-Hydroxynicotinate + NADPH + H+ R01721 S-adenosyl-L-methionine:nicotinate N-methyltransferase; S-Adenosyl-L-methionine + Nicotinate <=> S-Adenosyl-L-homocysteine + N-Methylnicotinate R01722 UDP-glucose:nicotinate N-glucosyltransferase; UDP-glucose + Nicotinate <=> UDP + N-Glucosylnicotinate R01723 Nicotinate + Glycine + ATP <=> Nicotinurate + AMP + Diphosphate R01724 5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming); Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+ R01728 prephenate:NAD+ oxidoreductase(decarboxylating); Prephenate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + CO2 + NADH + H+ R01730 prephenate:NADP+ oxidoreductase(decarboxylating); Prephenate + NADP+ <=> 3-(4-Hydroxyphenyl)pyruvate + CO2 + NADPH + H+ R01731 L-arogenate:2-oxoglutarate aminotransferase; Oxaloacetate + L-Arogenate <=> L-Aspartate + Prephenate R01732 riboflavin hydrolase; Riboflavin + H2O <=> Ribitol + Lumichrome R01734 Dimethylbenzimidazole <=> Riboflavin R01735 (R)-lactaldehyde:NAD+ 2-oxidoreductase; (R)-Lactaldehyde + NAD+ + H2O <=> (R)-Lactate + NADH + H+ R01736 (R)-S-lactoylglutathione hydrolase; (R)-S-Lactoylglutathione + H2O <=> Glutathione + (R)-Lactate R01737 ATP:D-gluconate 6-phosphotransferase; ATP + D-Gluconic acid <=> ADP + 6-Phospho-D-gluconate R01738 D-gluconate:NAD+ 5-oxidoreductase; D-Gluconic acid + NAD+ <=> 5-Dehydro-D-gluconate + NADH + H+ R01739 D-gluconate:NADP+ 2-oxidoreductase; D-Gluconic acid + NADP+ <=> 2-Keto-D-gluconic acid + NADPH + H+ R01740 D-gluconate:NADP+ 5-oxidoreductase; D-Gluconic acid + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ R01741 D-gluconate:(acceptor) 2-oxidoreductase; D-Gluconic acid + FAD <=> 2-Keto-D-gluconic acid + FADH2 R01742 D-gluconate:acceptor 2-oxidoreductase; D-Gluconic acid + Acceptor <=> 2-Keto-D-gluconic acid + Reduced acceptor R01745 (R)-glycerate:NAD+ oxidoreductase; D-Glycerate + NAD+ <=> 2-Hydroxy-3-oxopropanoate + NADH + H+ R01747 (R)-glycerate:NADP+ oxidoreductase; D-Glycerate + NADP+ <=> 2-Hydroxy-3-oxopropanoate + NADPH + H+ R01748 D-glycerate-2-phosphate phosphohydrolase; 2-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate R01749 D-glycerate:NAD+ oxidoreductase (carboxylating); D-Glycerate + NAD+ + CO2 <=> 2-Hydroxy-3-oxosuccinate + NADH + H+ R01750 D-glycerate:NADP+ oxidoreductase (carboxylating); D-Glycerate + NADP+ + CO2 <=> 2-Hydroxy-3-oxosuccinate + NADPH + H+ R01751 (R,R)-tartrate carboxy-lyase (D-glycerate-forming); (R,R)-Tartaric acid <=> D-Glycerate + CO2 R01752 D-glyceraldehyde:NAD+ oxidoreductase; D-Glyceraldehyde + NAD+ + H2O <=> D-Glycerate + NADH + H+ R01754 ATP:L-arabinose 1-phosphotransferase; ATP + L-Arabinose <=> ADP + beta-L-Arabinose 1-phosphate R01757 L-arabinose:NAD+ 1-oxidoreductase; L-Arabinose + NAD+ <=> L-Arabinono-1,4-lactone + NADH + H+ R01758 L-arabitol:NAD+ 1-oxidoreductase; L-Arabitol + NAD+ <=> L-Arabinose + NADH + H+ R01759 L-arabitol:NADP+ 1-oxidoreductase; L-Arabitol + NADP+ <=> L-Arabinose + NADPH + H+ R01760 beta-L-arabinoside arabinohydrolase; beta-L-Arabinoside + H2O <=> Alcohol + L-Arabinose R01761 L-arabinose aldose-ketose-isomerase; L-Arabinose <=> L-Ribulose R01762 alpha-L-arabinan arabinofuranohydrolase; Arabinan + H2O <=> Arabinan + L-Arabinose R01763 benzyl alcohol:NAD+ oxidoreductase; Benzyl alcohol + NAD+ <=> Benzaldehyde + NADH + H+ R01764 benzoylformate carboxy-lyase (benzaldehyde-forming); alpha-Oxo-benzeneacetic acid <=> Benzaldehyde + CO2 R01766 L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming); L-threo-3-Phenylserine <=> Glycine + Benzaldehyde R01767 mandelonitrile benzaldehyde-lyase (cyanide-forming); Mandelonitrile <=> Hydrogen cyanide + Benzaldehyde R01768 hypoxanthine:NAD+ oxidoreductase; Hypoxanthine + NAD+ + H2O <=> Xanthine + NADH + H+ R01769 hypoxanthine:oxygen oxidoreductase; Hypoxanthine + Oxygen + H2O <=> Xanthine + Hydrogen peroxide R01770 inosine ribohydrolase; Inosine + H2O <=> Hypoxanthine + D-Ribose R01771 ATP:L-homoserine O-phosphotransferase; ATP + L-Homoserine <=> ADP + O-Phospho-L-homoserine R01773 L-homoserine:NAD+ oxidoreductase; L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+ R01775 L-homoserine:NADP+ oxidoreductase; L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+ R01776 acetyl-CoA:L-homoserine O-acetyltransferase; Acetyl-CoA + L-Homoserine <=> CoA + O-Acetyl-L-homoserine R01777 succinyl-CoA:L-homoserine O-succinyltransferase; Succinyl-CoA + L-Homoserine <=> CoA + O-Succinyl-L-homoserine R01778 (3S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase; (3S)-3-Hydroxyacyl-CoA + NAD+ <=> 3-Oxoacyl-CoA + NADH + H+ R01779 (3R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase; (3R)-3-Hydroxyacyl-CoA + NADP+ <=> 3-Oxoacyl-CoA + NADPH + H+ R01780 succinyl-CoA:3-oxo-acid CoA-transferase; Succinyl-CoA + 3-Oxo acid <=> Succinate + 3-Oxoacyl-CoA R01781 1,2-ethanediol:NAD+ oxidoreductase; Ethylene glycol + NAD+ <=> Glycolaldehyde + NADH + H+ R01782 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-D-xylonate <=> Pyruvate + Glycolaldehyde R01784 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-L-arabinonate <=> Pyruvate + Glycolaldehyde R01785 L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming); L-Xylulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde R01786 ATP:alpha-D-glucose 6-phosphotransferase; ATP + alpha-D-Glucose <=> ADP + alpha-D-Glucose 6-phosphate R01787 D-glucitol:NADP+ 1-oxidoreductase; D-Sorbitol + NADP+ <=> alpha-D-Glucose + NADPH + H+ R01788 alpha-D-glucose 6-phosphate phosphohydrolase; alpha-D-Glucose 6-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate R01790 1,4-alpha-D-glucan glucohydrolase; Starch + H2O <=> D-Glucose + Starch R01791 dextrin 6-alpha-D-glucanohydrolase; Dextrin + H2O <=> D-Glucose + Dextrin R01793 5,6,7,8-tetrahydrobiopterin:NAD+ oxidoreductase; Dihydrobiopterin + NADH + H+ <=> Tetrahydrobiopterin + NAD+ R01794 5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase; Dihydrobiopterin + NADPH + H+ <=> Tetrahydrobiopterin + NADP+ R01795 L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating); Tetrahydrobiopterin + L-Phenylalanine + Oxygen <=> Dihydrobiopterin + L-Tyrosine + H2O R01797 CDP-diacylglycerol phosphatidylhydrolase; CDP-diacylglycerol + H2O <=> CMP + Phosphatidate R01798 arachidonyl-CoA:CDPacylglycerol O-arachidonyltransferase; Arachidonyl-CoA + CDP-acylglycerol <=> CoA + CDP-diacylglycerol R01799 CTP:phosphatidate cytidyltransferase; CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol R01800 CDP-diacylglycerol:L-serine 3-phosphatidyltransferase; CDP-diacylglycerol + L-Serine <=> CMP + Phosphatidylserine R01801 CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol + sn-Glycerol 3-phosphate <=> CMP + Phosphatidylglycerophosphate R01802 CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase; CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol R01803 N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating); N-Acetylneuraminate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Glycoloyl-neuraminate + 2 Ferricytochrome b5 + H2O R01804 phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-Acetylneuraminate + Orthophosphate <=> N-Acetyl-D-mannosamine + Phosphoenolpyruvate + H2O R01805 N-acetylneuraminate 9-phosphate phosphohydrolase; N-Acetylneuraminate 9-phosphate + H2O <=> N-Acetylneuraminate + Orthophosphate R01806 acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase; Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-4-O-acetylneuraminate R01807 acetyl-CoA:N-acetylneuraminate 7-O-acetyltransferase; Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-7-O-acetylneuraminate R01808 acetyl-CoA:N-acetylneuraminate 9-O-acetyltransferase; Acetyl-CoA + N-Acetylneuraminate <=> CoA + N-Acetyl-9-O-acetylneuraminate R01810 N-acyl-O-acetylneuraminate O-acetylesterase; N-Acetyl-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate R01811 N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming); N-Acetylneuraminate <=> N-Acetyl-D-mannosamine + Pyruvate R01812 5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase; Tetrahydrobiopterin + 2 NADP+ <=> Biopterin + 2 NADPH + 2 H+ R01813 tetrahydrobiopterin:NADP+ oxidoreductase; Tetrahydrobiopterin + NADP+ <=> 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ R01814 L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating); Tetrahydrobiopterin + L-Tryptophan + Oxygen <=> 5-Hydroxy-L-tryptophan + Dihydrobiopterin + H2O R01815 L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating); Tetrahydrobiopterin + L-Tyrosine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + Dihydrobiopterin + H2O R01817 D-mannitol-1-phosphate:NADP+ 6-oxidoreductase; D-Mannitol 1-phosphate + NADP+ <=> D-Mannose 6-phosphate + NADPH + H+ R01818 D-mannose 6-phosphate 1,6-phosphomutase; D-Mannose 6-phosphate <=> D-Mannose 1-phosphate R01819 D-mannose-6-phosphate aldose-ketose-isomerase; D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate R01821 1,4-alpha-D-glucan:orthophosphate alpha-D-glucosyltransferase; Amylose + Orthophosphate <=> Amylose + D-Glucose 1-phosphate R01823 sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase; Sucrose + Amylose <=> D-Fructose + Amylose R01824 maltodextrin 1-alpha-D-glucosylmutase; Maltodextrin <=> 1-alpha-D-[(1->4)-alpha-D-Glucosyl](n-1)-alpha-D-glucopyranoside R01825 D-erythrose 4-phosphate:NAD+ oxidoreductase; D-Erythrose 4-phosphate + NAD+ + H2O <=> 4-Phospho-D-erythronate + NADH + H+ R01826 phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming); Phosphoenolpyruvate + D-Erythrose 4-phosphate + H2O <=> 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + Orthophosphate R01827 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase; Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + beta-D-Fructose 6-phosphate R01829 sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase; Sedoheptulose 1,7-bisphosphate <=> Glycerone phosphate + D-Erythrose 4-phosphate R01830 beta-D-fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate R01833 androst-4-ene-3,17-dione,hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing); Androstenedione + Reduced acceptor + Oxygen <=> Testololactone + Acceptor + H2O R01834 3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase; 5alpha-Androstane-3,17-dione + Acceptor <=> Androstenedione + Reduced acceptor R01835 5beta-androstane-3,17-dione:NADP+ 4,5-oxidoreductase; 5beta-Androstane-3,17-dione + NADP+ <=> H+ + NADPH + Androstenedione R01836 testosterone:NAD+ 17-oxidoreductase; Testosterone + NAD+ <=> Androstenedione + NADH + H+ R01837 3beta-hydroxyandrost-5-en-17-one:NAD+ 3-oxidoreductase/delta5-delta-4 isomerase; Dehydroepiandrosterone + NAD+ <=> Androstenedione + NADH + H+ R01838 testosterone:NADP+ 17-oxidoreductase; Testosterone + NADP+ <=> Androstenedione + NADPH + H+ R01840 androstenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (19-hydroxylating); Androstenedione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxyandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + H2O R01842 androstenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating); Androstenedione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha-Hydroxyandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + H2O R01843 ATP:sedoheptulose 7-phosphate 1-phosphotransferase; ATP + Sedoheptulose 7-phosphate <=> ADP + Sedoheptulose 1,7-bisphosphate R01844 ATP:sedoheptulose 7-phosphate; ATP + Sedoheptulose <=> ADP + Sedoheptulose 7-phosphate R01845 sedoheptulose 1,7-bisphosphate 1-phosphohydrolase; Sedoheptulose 1,7-bisphosphate + H2O <=> Sedoheptulose 7-phosphate + Orthophosphate R01850 acetyl-CoA:hydrogen-sulfide S-acetyltransferase; Acetyl-CoA + Hydrogen sulfide <=> CoA + Thioacetate R01851 methanethiol:oxygen oxidoreductase; Methanethiol + Oxygen + H2O <=> Hydrogen sulfide + Formaldehyde + Hydrogen peroxide R01853 RCH2NH2:oxygen oxidoreductase (deaminating) (copper-containing); RCH2NH2 + H2O + Oxygen <=> Aldehyde + Ammonia + Hydrogen peroxide R01854 RCH2NH2:acceptor oxidoreductase (deaminating); aralkylamine:acceptor oxidoreductase (deaminating); RCH2NH2 + H2O + Acceptor <=> Aldehyde + Ammonia + Reduced acceptor R01855 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase; dGTP + H2O <=> dGMP + Diphosphate R01856 dGTP triphosphohydrolase; dGTP + H2O <=> Deoxyguanosine + Triphosphate R01857 ATP:dGDP phosphotransferase; ATP + dGDP <=> ADP + dGTP R01858 dGTP:pyruvate 2-O-phosphotransferase; dGTP + Pyruvate <=> dGDP + Phosphoenolpyruvate R01859 propanoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA R01860 4-aminobenzoate carboxy-lyase; 4-Aminobenzoate <=> Aniline + CO2 R01861 3'-phosphoadenylyl-sulfate:benzenamine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + Aniline <=> Adenosine 3',5'-bisphosphate + Benzenamine sulfate R01862 anilide amidohydrolase; Anilide + H2O <=> Carboxylate + Aniline R01863 inosine:phosphate alpha-D-ribosyltransferase; Inosine + Orthophosphate <=> Hypoxanthine + alpha-D-Ribose 1-phosphate R01866 (S)-dihydroorotate:NADP+ oxidoreductase; (S)-Dihydroorotate + NADP+ <=> Orotate + NADPH + H+ R01867 (S)-dihydroorotate:fumarate oxidoreductase; (S)-Dihydroorotate + Fumarate <=> Orotate + Succinate R01868 (S)-dihydroorotate:quinone oxidoreductase; (S)-Dihydroorotate + Quinone <=> Orotate + Hydroquinone R01869 (S)-dihydroorotate:NAD+ oxidoreductase; (S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH R01870 orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase; Orotidine 5'-phosphate + Diphosphate <=> Orotate + 5-Phospho-alpha-D-ribose 1-diphosphate R01872 L-quinate:NAD+ 3-oxidoreductase; quinate:NAD+ 5-oxidoreductase; Quinate + NAD+ <=> 3-Dehydroquinate + NADH + H+ R01873 quinate:pyrroloquinoline-quinone 3-oxidoreductase; quinate:pyrroloquinoline-quinone 5-oxidoreductase; Quinate + PQQ <=> PQQH2 + 3-Dehydroquinate R01874 D-cysteine sulfide-lyase (deaminating; pyruvate-forming); D-Cysteine + H2O <=> Hydrogen sulfide + Ammonia + Pyruvate R01875 thiosulfate:thiol sulfurtransferase; Thiosulfate + 2 Glutathione + H+ <=> Sulfite + Glutathione disulfide + Hydrogen sulfide R01876 uridine:phosphate alpha-D-ribosyltransferase; Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate R01877 uridine 3'-monophosphate phosphohydrolase; 3'-UMP + H2O <=> Uridine + Orthophosphate R01878 cytidine aminohydrolase; Cytidine + H2O <=> Uridine + Ammonia R01879 2-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating); Deoxyuridine + 2-Oxoglutarate + Oxygen <=> Uridine + Succinate + CO2 R01881 ATP:creatine N-phosphotransferase; ATP + Creatine <=> ADP + Phosphocreatine R01882 N-phosphocreatine hydrolase; Phosphocreatine + H2O <=> Creatine + Orthophosphate R01883 S-adenosyl-L-methionine:guanidinoacetate N-methyltransferase; S-Adenosyl-L-methionine + Guanidinoacetate <=> S-Adenosyl-L-homocysteine + Creatine R01884 creatinine amidohydrolase; Creatinine + H2O <=> Creatine R01885 ADP-ribose + H2O <=> alpha-D-Ribose 1-phosphate + AMP R01886 Nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase; N(omega)-(ADP-D-ribosyl)-L-arginine + H2O <=> L-Arginine + ADP-ribose R01887 gamma-amino-gamma-cyanobutanoate aminohydrolase; gamma-Amino-gamma-cyanobutanoate + 2 H2O <=> Glutamate + Ammonia R01888 ATP:kanamycin 3'-O-phosphotransferase; ATP + Kanamycin A <=> ADP + Kanamycin A 3'-phosphate R01889 acetyl-CoA:kanamycin-B N6'-acetyltransferase; Acetyl-CoA + Kanamycin B <=> CoA + N6'-Acetylkanamycin-B R01890 CTP:choline-phosphate cytidylyltransferase; CTP + Choline phosphate <=> Diphosphate + CDP-choline R01891 CDP-choline:N-acylsphingosine cholinephosphotransferase; CDP-choline + N-Acylsphingosine <=> CMP + Sphingomyelin R01892 ribitol:ferricytochrome-c 2-oxidoreductase; Ribitol + 2 Ferricytochrome c <=> D-Ribulose + 2 Ferrocytochrome c + 2 H+ R01895 ribitol:NAD+ 2-oxidoreductase; Ribitol + NAD+ <=> D-Ribulose + NADH + H+ R01896 xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming); Xylitol + NAD+ <=> D-Xylulose + NADH + H+ R01898 D-lyxose aldose-ketose-isomerase; D-Xylulose <=> D-Lyxose R01899 isocitrate:NADP+ oxidoreductase; Isocitrate + NADP+ <=> Oxalosuccinate + NADPH + H+ R01900 isocitrate hydro-lyase (cis-aconitate-forming); Isocitrate <=> cis-Aconitate + H2O R01901 ATP:L-xylulose 5-phosphotransferase; ATP + L-Xylulose <=> ADP + L-Xylulose 5-phosphate R01902 ATP:L-xylulose 1-phosphotransferase; ATP + L-Xylulose <=> ADP + L-Xylulose 1-phosphate R01903 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming); L-Arabitol + NAD+ <=> L-Xylulose + NADH + H+ R01904 xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming); Xylitol + NADP+ <=> L-Xylulose + NADPH + H+ R01905 3-dehydro-L-gulonate carboxy-lyase; 3-Dehydro-L-gulonate <=> L-Xylulose + CO2 R01906 L-lyxose aldose-ketose-isomerase; L-Xylulose <=> L-Lyxose R01908 oxalyl-CoA carboxy-lyase (formyl-CoA-forming); Oxalyl-CoA <=> Formyl-CoA + CO2 R01909 ATP:pyridoxine 5'-phosphotransferase; ATP + Pyridoxine <=> ADP + Pyridoxine phosphate R01910 primary alcohol:(acceptor) oxidoreductase; Pyridoxine + Oxygen <=> Isopyridoxal + Hydrogen peroxide R01911 pyridoxine-5'-phosphate phosphohydrolase; Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O R01912 UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase; UDP-glucose + Pyridoxine <=> UDP + 5'-O-beta-D-Glucosylpyridoxine R01913 Pyridoxine <=> 1-Deoxy-D-xylulose + 4-Hydroxy-L-threonine R01914 spermidine:(acceptor) oxidoreductase; Spermidine + Oxygen + H2O <=> 1,3-Diaminopropane + 4-Aminobutyraldehyde + Hydrogen peroxide R01915 spermidine:(acceptor) oxidoreductase; Spermidine + Acceptor + H2O <=> 1,3-Diaminopropane + 4-Aminobutyraldehyde + Reduced acceptor R01917 gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming); ATP + Glutathione + Spermidine <=> ADP + Orthophosphate + Glutathionylspermidine R01918 gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase; Glutathionylspermidine + H2O <=> Glutathione + Spermidine R01919 spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming); Putrescine + Spermidine <=> sym-Homospermidine + 1,3-Diaminopropane R01920 S-adenosylmethioninamine:putrescine 3-aminopropyltransferase; S-Adenosylmethioninamine + Putrescine <=> 5'-Methylthioadenosine + Spermidine R01921 (S)-carnitine:NAD+ oxidoreductase; (S)-Carnitine + NAD+ <=> 3-Dehydrocarnitine + NADH + H+ R01922 L-carnitinamide amidohydrolase; L-Carnitinamide + H2O <=> L-Carnitine + Ammonia + H+ R01923 palmitoyl-CoA:L-carnitine O-palmitoyltransferase; Palmitoyl-CoA + L-Carnitine <=> CoA + L-Palmitoylcarnitine R01924 O-acylcarnitine acylhydrolase; O-Acylcarnitine + H2O <=> Fatty acid + L-Carnitine R01926 ATP:sphingosine 1-phosphotransferase; sphingosine kinase; Sphingosine + ATP <=> Sphingosine 1-phosphate + ADP R01928 UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase; UDP-alpha-D-galactose + Sphingosine <=> UDP + Psychosine R01929 CDP-choline:sphingosine cholinephosphotransferase; CDP-choline + Sphingosine <=> CMP + Sphingosyl-phosphocholine R01930 trithionate thiosulfohydrolase; Trithionate + H2O <=> Thiosulfate + Sulfate R01931 thiosulfate:cyanide sulfurtranserase; Thiosulfate + Cyanide ion <=> Sulfite + Thiocyanate R01932 2-hydroxyadipate:NAD+ 2-oxidoreductase; 2-Oxoadipate + NADH + H+ <=> 2-Hydroxyadipate + NAD+ R01933 2-oxoadipate dehydrogenase complex; 2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+ R01934 (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating); homoisocitrate:NAD+ oxidoreductase (decarboxylating); Homoisocitrate + NAD+ <=> 2-Oxoadipate + CO2 + NADH + H+ R01936 (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating); Oxaloglutarate <=> 2-Oxoadipate + CO2 R01937 2-Oxoadipate + Ammonia + NAD+ <=> 2-Aminomuconate + NADH + H+ + H2O R01938 2-Oxoadipate + Ammonia + NADP+ <=> 2-Aminomuconate + NADPH + H+ + H2O R01939 L-2-aminoadipate:2-oxoglutarate aminotransferase; L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate R01940 2-oxoadipate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating); 2-Oxoadipate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + CO2 R01941 caffeic aldehyde:NADP+ oxidoreductase (CoA-caffeoylating); Caffeic aldehyde + CoA + NADP+ <=> Caffeoyl-CoA + NADPH + H+ R01942 S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase; S-Adenosyl-L-methionine + Caffeoyl-CoA <=> S-Adenosyl-L-homocysteine + Feruloyl-CoA R01943 caffeate:CoA ligase (AMP-forming); 3,4-dihydroxy-trans-cinnamate:CoA ligase (AMP-forming); ATP + Caffeate + CoA <=> AMP + Diphosphate + Caffeoyl-CoA R01944 caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase; Caffeoyl-CoA + Putrescine <=> CoA + N-Caffeoylputrescine R01945 caffeoyl-CoA:quinate O-(3,4-dihydroxycinnamoyl)transferase; Caffeoyl-CoA + Quinate <=> CoA + Chlorogenate R01946 caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase; Caffeoyl-CoA + Isocitrate <=> CoA + 2-Caffeoylisocitrate R01951 GTP:beta-L-fucose-1-phosphate guanylyltransferase; GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose R01952 palmitoyl-CoA:glycoprotein N-palmitoyltransferase; Palmitoyl-CoA + Glycoprotein <=> CoA + N-Palmitoylglycoprotein R01954 L-citrulline:L-aspartate ligase (AMP-forming); ATP + L-Citrulline + L-Aspartate <=> AMP + Diphosphate + N-(L-Arginino)succinate R01956 L-kynurenine:2-oxoglutarate aminotransferase; L-Kynurenine + 2-Oxoglutarate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate R01957 L-kynurenine:glyoxylote aminotransferase (cyclizing); L-Kynurenine + Glyoxylate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine R01959 N-formyl-L-kynurenine amidohydrolase; L-Formylkynurenine + H2O <=> Formate + L-Kynurenine R01960 L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating); L-Kynurenine + Oxygen + NADPH + H+ <=> 3-Hydroxy-L-kynurenine + NADP+ + H2O R01961 ATP:D-glucosamine 6-phosphotransferase; ATP + D-Glucosamine <=> ADP + D-Glucosamine 6-phosphate R01962 D-glucosamine:oxygen 1-oxidoreductase; D-Glucosamine + Oxygen + H2O <=> 2-Amino-2-deoxy-D-gluconate + Hydrogen peroxide R01963 N-sulfo-D-glucosamine sulfohydrolase; N-Sulfo-D-glucosamine + H2O <=> D-Glucosamine + Sulfate R01964 ITP:D-glucosamine 6-phosphotransferase; ITP + D-Glucosamine <=> IDP + D-Glucosamine 6-phosphate R01965 dATP:D-glucosamine 6-phosphotransferase; dATP + D-Glucosamine <=> dADP + D-Glucosamine 6-phosphate R01966 beta-D-glucosaminide glucosaminohydrolase; D-Glucosamine + D-Glucosaminide <=> D-Glucosaminide + H2O R01967 ATP:deoxyguanosine 5'-phosphotransferase; ATP + Deoxyguanosine <=> ADP + dGMP R01968 2'-deoxyguanosine 5'-monophosphate phosphohydrolase; dGMP + H2O <=> Deoxyguanosine + Orthophosphate R01969 deoxyguanosine:orthophosphate ribosyltransferase; Deoxyguanosine + Orthophosphate <=> Guanine + 2-Deoxy-D-ribose 1-phosphate R01972 S-adenosyl-L-methionine:(indol-3-yl)pyruvate C3-methyltransferase; S-Adenosyl-L-methionine + Indolepyruvate <=> S-Adenosyl-L-homocysteine + (R)-3-(Indol-3-yl)-2-oxobutyrate R01973 S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase; S-Adenosyl-L-methionine + Indolepyruvate <=> S-Adenosyl-L-homocysteine + 3-Methylindolepyruvate R01974 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]; Indolepyruvate <=> Indole-3-acetaldehyde + CO2 R01975 (S)-3-hydroxybutanoyl-CoA:NAD+ oxidoreductase; (S)-3-Hydroxybutanoyl-CoA + NAD+ <=> Acetoacetyl-CoA + NADH + H+ R01976 (S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase; (S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+ R01977 (R)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase; (R)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+ R01978 acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); (S)-3-Hydroxy-3-methylglutaryl-CoA + CoA <=> Acetyl-CoA + H2O + Acetoacetyl-CoA R01980 ATP:D-galacturonate 1-phosphotransferase; ATP + D-Galacturonate <=> ADP + 1-Phospho-alpha-D-galacturonate R01981 D-Galacturonate + NAD+ + H2O <=> D-Galactarate + NADH + H+ R01982 poly(1,4-alpha-D-galacturonate) galacturonohydrolase; Pectate + H2O <=> D-Galacturonate + Pectate R01983 D-galacturonate aldose-ketose-isomerase; D-Galacturonate <=> D-Tagaturonate R01984 D-Galacturonate <=> D-Galacturonolactone + H2O R01986 4-aminobutyraldehyde:NAD+ oxidoreductase; 4-Aminobutyraldehyde + NADP+ + H2O <=> 4-Aminobutanoate + NADPH + H+ R01987 4-acetamidobutanoate amidohydrolase; 4-Aminobutanoate + Acetate <=> 4-Acetamidobutanoate + H2O R01989 L-arginine:4-aminobutanoate amidinotransferase; L-Arginine + 4-Aminobutanoate <=> L-Ornithine + 4-Guanidinobutanoate R01990 4-guanidinobutanoate amidinohydrolase; 4-Guanidinobutanoate + H2O <=> 4-Aminobutanoate + Urea R01991 L-histidine:4-aminobutanoate ligase (ADP-forming); ATP + L-Histidine + 4-Aminobutanoate <=> ADP + Orthophosphate + Homocarnosine R01992 alpha-aminobutyryl histidine hydrolase; Homocarnosine + H2O <=> 4-Aminobutanoate + L-Histidine R01993 (S)-dihydroorotate amidohydrolase; (S)-Dihydroorotate + H2O <=> N-Carbamoyl-L-aspartate R01994 UDPglucose:lipopolysaccharide glucosyltransferase; UDP-glucose + Lipopolysaccharide <=> UDP + D-Glucosyllipopolysaccharide R01995 UDPglucose:arylamine N-D-glucosyltransferase; UDP-glucose + Lipopolysaccharide <=> UDP + alpha-D-Glucosyllipopolysaccharide R01996 UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetylglucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Lipopolysaccharide <=> UDP + N-Acetyl-D-glucosaminyllipopolysaccharide R01997 UDP-alpha-D-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + Lipopolysaccharide <=> UDP + 3-alpha-D-Galactosyl-[lipopolysaccharide glucose] R01998 long-chain-alcohol:NAD+ oxidoreductase; Long-chain alcohol + H2O + 2 NAD+ <=> Long-chain carboxylate + 2 NADH + 2 H+ R01999 acyl-CoA:long-chain-alcohol O-acyltransferase; Acyl-CoA + Long-chain alcohol <=> CoA + Long-chain ester R02000 rubredoxin:NAD+ oxidoreductase; 2 Reduced rubredoxin + NAD+ + H+ <=> 2 Oxidized rubredoxin + NADH R02002 rubredoxin:NADP+ oxidoreductase; 2 Reduced rubredoxin + NADP+ + H+ <=> 2 Oxidized rubredoxin + NADPH R02003 geranyl-diphosphate:isopentenyl-diphosphate geranyltrans-transferase; Geranyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + trans,trans-Farnesyl diphosphate R02004 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]; Geranyl diphosphate + H2O <=> (-)-endo-Fenchol + Diphosphate R02006 geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming); Geranyl diphosphate + H2O <=> Sabinene hydrate + Diphosphate R02007 (+)-bornyl-diphosphate lyase (decyclizing); (+)-Bornyl diphosphate <=> Geranyl diphosphate R02008 (6E)-8-Oxogeranial <=> Iridodial R02009 geranyldiphosphate diphosphate-lyase (myrcene-forming); Geranyl diphosphate <=> Myrcene + Diphosphate R02010 geranyl-diphosphate diphosphate-lyase (cyclizing, terpinolene-forming); Geranyl diphosphate <=> Terpinolene + Diphosphate R02011 geranyl-diphosphate diphosphate-lyase (cyclizing, comphene-forming); Geranyl diphosphate <=> Camphene + Diphosphate R02013 geranyl-diphosphate diphosphate-lyase [cyclizing; (4S)-limonene-forming]; Geranyl diphosphate <=> (S)-Limonene + Diphosphate R02014 2'-deoxyadenosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dATP + Thioredoxin disulfide + H2O <=> ATP + Thioredoxin R02016 NADPH:oxidized-thioredoxin oxidoreductase; Thioredoxin + NADP+ <=> Thioredoxin disulfide + NADPH + H+ R02017 2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP R02018 2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP R02019 2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dGDP + Thioredoxin disulfide + H2O <=> GDP + Thioredoxin R02020 2'-deoxyguanosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dGTP + Thioredoxin disulfide + H2O <=> GTP + Thioredoxin R02021 adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate -forming); Thioredoxin + 3'-Phosphoadenylyl sulfate <=> Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate R02022 2'-deoxyuridine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dCTP + Thioredoxin disulfide + H2O <=> CTP + Thioredoxin R02023 2'-deoxyuridine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dUTP + Thioredoxin disulfide + H2O <=> UTP + Thioredoxin R02024 2'-deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dCDP + Thioredoxin disulfide + H2O <=> Thioredoxin + CDP R02025 L-methionine:oxidized-thioredoxin S-oxidoreductase; L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine S-oxide + Thioredoxin R02026 O-acetyl-L-homoserine acetate-lyase (L-homocysteine forming); O-Acetyl-L-homoserine + Thiosulfate + Thioredoxin + H+ <=> L-Homocysteine + Sulfite + Thioredoxin disulfide + Acetate R02027 phosphatidylglycerol cholinephosphohydrolase; Phosphatidylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + sn-Glycerol 3-phosphate R02029 phosphatidylglycerophosphate phosphohydrolase; Phosphatidylglycerophosphate + H2O <=> Phosphatidylglycerol + Orthophosphate R02030 CDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase; Phosphatidylglycerol + CDP-diacylglycerol <=> Cardiolipin + CMP R02032 6-phospho-2-dehydro-D-gluconate:NAD+ 2-oxidoreductase; 6-Phospho-D-gluconate + NAD+ <=> 6-Phospho-2-dehydro-D-gluconate + NADH + H+ R02034 6-phospho-D-gluconate:NADP+ 2-oxidoreductase; 6-Phospho-D-gluconate + NADP+ <=> 6-Phospho-2-dehydro-D-gluconate + NADPH + H+ R02035 6-phospho-D-glucono-1,5-lactone lactonohydrolase; D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate R02036 6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming); 6-Phospho-D-gluconate <=> 2-Dehydro-3-deoxy-6-phospho-D-gluconate + H2O R02037 S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase; S-Adenosyl-L-methionine + Ethanolamine phosphate <=> S-Adenosyl-L-homocysteine + N-Methylethanolamine phosphate R02038 CTP:ethanolamine-phosphate cytidylyltransferase; CTP + Ethanolamine phosphate <=> Diphosphate + CDP-ethanolamine R02039 long-chain-aldehyde:NAD+ oxidoreductase; Long-chain aldehyde + NAD+ + H2O <=> Long-chain carboxylate + NADH + H+ R02040 N-long-chain-fatty-acyl-L-glutamate amidohydrolase; N-Long-chain-fatty-acyl-L-glutamate + H2O <=> Long-chain carboxylate + L-Glutamate R02041 N-(long-chain-acyl)ethanolamine amidohydrolase; N-(Long-chain-acyl)ethanolamine + H2O <=> Long-chain carboxylate + Ethanolamine R02042 wax-ester acylhydrolase; Wax ester + H2O <=> Long-chain alcohol + Long-chain carboxylate R02047 3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase; 3-Hydroxy-2-methylpropanoate + NAD+ <=> 2-Methyl-3-oxopropanoate + NADH + H+ R02050 (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase; (R)-3-Amino-2-methylpropanoate + Pyruvate <=> 2-Methyl-3-oxopropanoate + L-Alanine R02051 phosphatidylethanolamine phosphatidohydrolase; Phosphatidylethanolamine + H2O <=> Ethanolamine + Phosphatidate R02052 phosphatidylethanolamine ethanolaminephosphohydrolase; Phosphatidylethanolamine + H2O <=> 1,2-Diacyl-sn-glycerol + Ethanolamine phosphate R02053 phosphatidylethanolamine 2-acylhydrolase; Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid R02054 phosphatidylethanolamine 1-acylhydrolase; Phosphatidylethanolamine + H2O <=> 2-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid R02055 phsophatidyl-L-serine carboxy-lyase; Phosphatidylserine <=> Phosphatidylethanolamine + CO2 R02056 S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine R02057 CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase; CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine R02058 acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase; Acetyl-CoA + D-Glucosamine 6-phosphate <=> CoA + N-Acetyl-D-glucosamine 6-phosphate R02059 N-acetyl-D-glucosamine-6-phosphate amidohydrolase; N-Acetyl-D-glucosamine 6-phosphate + H2O <=> D-Glucosamine 6-phosphate + Acetate R02060 D-glucosamine 1-phosphate 1,6-phosphomutase; D-glucosamine 1,6-phosphomutase; alpha-D-Glucosamine 1-phosphate <=> D-Glucosamine 6-phosphate R02061 trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase; trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranylgeranyl diphosphate R02063 geranylgeranyl reductase; Geranylgeranyl diphosphate + 3 H+ + 3 NADPH <=> Phytyl diphosphate + 3 NADP+ R02064 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing); Geranylgeranyl diphosphate <=> Casbene + Diphosphate R02065 geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (prephytoene-diphosphate-forming); 2 Geranylgeranyl diphosphate <=> Diphosphate + Prephytoene diphosphate R02068 ent-copalyl-diphosphate lyase; Geranylgeranyl diphosphate <=> ent-Copalyl diphosphate R02071 ATP:D-fructose-1-phosphate 6-phosphotransferase; ATP + D-Fructose 1-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate R02073 diphosphate:beta-D-fructose-6-phosphate 1-phosphotransferase; Diphosphate + beta-D-Fructose 6-phosphate <=> Orthophosphate + beta-D-Fructose 1,6-bisphosphate R02075 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing); 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde R02076 3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing); 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde R02077 3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase; 3,4-Dihydroxy-L-phenylalanine + 2-Oxoglutarate <=> 3-(3,4-Dihydroxyphenyl)pyruvate + L-Glutamate R02078 L-tyrosine,L-dopa:oxygen oxidoreductase; 3,4-Dihydroxy-L-phenylalanine + L-Tyrosine + Oxygen <=> Dopaquinone + 3,4-Dihydroxy-L-phenylalanine + H2O R02080 3,4-dihydroxy-L-phenylalanine carboxy-lyase; 3,4-Dihydroxy-L-phenylalanine <=> Dopamine + CO2 R02081 (R)-mevalonate:NAD+ oxidoreductase (CoA-acetylating); (R)-Mevalonate + CoA + 2 NAD+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ R02082 (R)-mevalonate:NADP+ oxidoreductase (CoA acylating); (R)-Mevalonate + CoA + 2 NADP+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ R02083 (S)-3-hydroxy-3-methylglutaryl-CoA hydrolase; (S)-3-Hydroxy-3-methylglutaryl-CoA + H2O <=> CoA + 3-Hydroxy-3-methylglutarate R02084 succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase; Succinyl-CoA + 3-Hydroxy-3-methylglutarate <=> Succinate + (S)-3-Hydroxy-3-methylglutaryl-CoA R02085 (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming); (S)-3-Hydroxy-3-methylglutaryl-CoA <=> 3-Methylglutaconyl-CoA + H2O R02087 N-acetyl-D-glucosamine 6-phosphate 2-epimerase; N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-D-mannosamine 6-phosphate R02088 2'-deoxyadenosine 5'-monophosphate phosphohydrolase; dAMP + H2O <=> Deoxyadenosine + Orthophosphate R02089 ATP:deoxyadenosine 5'-phosphotransferase; ATP + Deoxyadenosine <=> ADP + dAMP R02090 ATP:dGMP phosphotransferase; ATP + dGMP <=> ADP + dGDP R02092 dTDP phosphohydrolase; dTDP + H2O <=> dTMP + Orthophosphate R02093 ATP:dTDP phosphotransferase; ATP + dTDP <=> ADP + dTTP R02094 ATP:dTMP phosphotransferase; ATP + dTMP <=> ADP + dTDP R02095 dTTP nucleotidohydrolase; dTTP + H2O <=> dTDP + Orthophosphate R02098 ATP:dUMP phosphotransferase; ATP + dUMP <=> ADP + dUDP R02099 ATP:deoxyuridine 5'-phosphotransferase; ATP + Deoxyuridine <=> ADP + dUMP R02100 dUTP nucleotidohydrolase; dUTP + H2O <=> dUMP + Diphosphate R02101 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase; dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP R02102 2'-deoxyuridine 5'-monophosphate phosphohydrolase; dUMP + H2O <=> Deoxyuridine + Orthophosphate R02103 xanthine:NAD+ oxidoreductase; Xanthine + NAD+ + H2O <=> Urate + NADH + H+ R02106 urate:oxygen oxidoreductase; Urate + Oxygen + H2O <=> 5-Hydroxyisourate + Hydrogen peroxide R02107 xanthine:oxygen oxidoreductase; Xanthine + H2O + Oxygen <=> Urate + Hydrogen peroxide R02108 1,4-alpha-D-glucan glucanohydrolase; Starch + H2O <=> Dextrin + Starch R02109 dextrin 6-alpha-D-glucanohydrolase; Starch + H2O <=> Amylose + alpha-D-Glucose R02110 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase; Amylose <=> Starch R02111 1,4-alpha-D-glucan:orthophosphate alpha-D-glucosyltransferase; Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate R02112 1,4-alpha-D-glucan maltohydrolase; Starch <=> Dextrin + Maltose R02113 UDPglucose:sterol 3-O-beta-D-glucosyltransferase; UDP-glucose + Sterol <=> UDP + Sterol 3-beta-D-glucoside R02114 phosphatidylcholine:sterol O-acyltransferase; Phosphatidylcholine + Sterol <=> 1-Acyl-sn-glycero-3-phosphocholine + Steryl ester R02115 steryl-ester acylhydrolase; Steryl ester + H2O <=> Sterol + Fatty acid R02116 Sterol <=> (S)-2,3-Epoxysqualene R02118 UDPglucose:zeatin O-beta-D-glucosyltransferase; UDP-glucose + Zeatin <=> UDP + O-beta-D-Glucosylzeatin R02119 UDP-D-xylose:zeatin O-beta-D-xylosyltransferase; UDP-D-xylose + Zeatin <=> UDP + O-beta-D-Xylosylzeatin R02120 sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase; Sucrose + Dextran <=> D-Fructose + Dextran R02121 1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase; Dextran + Amylose <=> Dextran + Amylose R02122 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + [Heparan sulfate]-glucosamine <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-N-sulfoglucosamine R02123 retinal:NAD+ oxidoreductase; Retinal + NAD+ + H2O <=> Retinoate + NADH + H+ R02124 retinol:NAD+ oxidoreductase; Retinol + NAD+ <=> Retinal + NADH + H+ R02125 retinal:oxygen oxidoreductase; Retinal + Oxygen + H2O <=> Retinoate + Hydrogen peroxide R02126 all-trans-retinal 11-cis-trans-isomerase; Retinal <=> 11-cis-Retinal R02127 Retinal <=> Metarhodopsin R02128 Retinal <=> Iodopsin + hn R02129 Retinal <=> all-trans-Dehydroretinal R02130 steroid,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 21-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O R02131 steroid,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O R02132 thiamin:oxygen 5-oxidoreductase; Thiamine + 2 Oxygen + H2O <=> Thiamine acetic acid + 2 Hydrogen peroxide R02133 thiamin hydrolase; Thiamine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-Hydroxyethyl)-4-methylthiazole + H+ R02134 ATP:thiamine phosphotransferase; ATP + Thiamine <=> ADP + Thiamin monophosphate R02135 thiamin monophosphate phosphohydrolase; Thiamin monophosphate + H2O <=> Thiamine + Orthophosphate R02136 ATP:xylitol 5-phosphotransferase; ATP + Xylitol <=> ADP + Xylitol 5-phosphate R02137 cytidine ribohydrolase; Cytidine + H2O <=> Cytosine + D-Ribose R02138 palmitoyl-CoA:dolichol O-palmitoyltransferase; Palmitoyl-CoA + Dolichol <=> CoA + Dolichyl palmitate R02139 barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming); Barbiturate + H2O <=> 3-Oxo-3-ureidopropanoate R02141 Xanthine + H2O <=> 5-Ureido-4-imidazole carboxylate R02142 XMP:pyrophosphate phosphoribosyltransferase; Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate R02143 xanthosine ribohydrolase; Xanthosine + H2O <=> Xanthine + D-Ribose R02144 S-adenosyl-L-methionine:carnosine N-methyltransferase; S-Adenosyl-L-methionine + Carnosine <=> S-Adenosyl-L-homocysteine + beta-Alanyl-N(pi)-methyl-L-histidine R02145 guanosine aminohydrolase; Guanosine + H2O <=> Xanthosine + Ammonia R02147 guanosine:phosphate alpha-D-ribosyltransferase; Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate R02148 guanosine 3'-phosphate phosphohydrolase; Guanosine 3'-phosphate + H2O <=> Guanosine + Orthophosphate R02150 1H-imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) (copper-containing); Histamine + Oxygen + H2O <=> Imidazole-4-acetaldehyde + Ammonia + Hydrogen peroxide R02152 Histamine + Acetyl-CoA <=> 4-(beta-Acetylaminoethyl)imidazole + CoA R02155 S-adenosyl-L-methionine:histamine N-tele-methyltransferase; S-Adenosyl-L-methionine + Histamine <=> S-Adenosyl-L-homocysteine + N-Methylhistamine R02156 quercetin:oxygen 2,3-oxidoreductase (decyclizing); Quercetin + Oxygen <=> 2-Protocatechoylphloroglucinolcarboxylate + CO R02157 S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyfavone 3-O-methyltransferase; S-Adenosyl-L-methionine + Quercetin <=> S-Adenosyl-L-homocysteine + 3-O-Methylquercetin R02158 UDPglucose:flavonol 3-O-D-glucosyltransferase; UDP-glucose + Quercetin <=> UDP + Isoquercitrin R02159 3'-phosphoadenylylsulfate:quercetin 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin <=> Adenosine 3',5'-bisphosphate + Quercetin 3-sulfate R02160 dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase; Taxifolin + 2-Oxoglutarate + Oxygen <=> Quercetin + Succinate + CO2 + H2O R02161 ubiquinol:ferricytochrome-c oxidoreductase; Ubiquinol + 2 Ferricytochrome c <=> Ubiquinone + 2 Ferrocytochrome c + 2 H+ R02163 NADH:ubiquinone oxidoreductase; Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+ R02164 succinate:quinone oxidoreductase; Quinone + Succinate <=> Hydroquinone + Fumarate R02165 nitrite:(acceptor) oxidoreductase; Ubiquinol + Nitrate <=> Ubiquinone + Nitrite + H2O R02167 D-mannitol-1-phosphate phosphohydrolase; D-Mannitol 1-phosphate + H2O <=> Mannitol + Orthophosphate R02168 GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; GDP-glucose + D-Glucose 6-phosphate <=> GDP + alpha,alpha'-Trehalose 6-phosphate R02170 penicillin amidohydrolase; Penicillin + H2O <=> Carboxylate + 6-Aminopenicillanate R02171 pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase; Pyrimidine 5'-nucleotide + H2O <=> Pyrimidine + D-Ribose 5-phosphate + H+ R02172 pyrimidine-nucleoside ribohydrolase; Pyrimidine nucleoside + H2O <=> Pyrimidine + D-Ribose + H+ R02173 tryptamine:oxygen oxidoreductase(deaminating); Tryptamine + H2O + Oxygen <=> Indole-3-acetaldehyde + Ammonia + Hydrogen peroxide R02174 S-adenosyl-L-methionine:amine N-methyltransferase; S-Adenosyl-L-methionine + Tryptamine <=> S-Adenosyl-L-homocysteine + N-Methyltryptamine R02177 (-)-menthol:NADP+ oxidoreductase; (-)-Menthol + NADP+ <=> (-)-Menthone + NADPH + H+ R02178 (-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating); (-)-Menthol + Oxygen + NADPH + H+ <=> p-Menthane-3,8-diol + NADP+ + H2O R02179 UDPglucose:(-)-menthol O-beta-D-glucosyltransferase; UDP-glucose + (-)-Menthol <=> UDP + (-)-Menthyl O-beta-D-glucoside R02180 3'-phosphoadenylylsulfate:chondroitin 4'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 4-sulfate R02181 3'-phosphoadenylylsulfate:chondroitin 6'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 6-sulfate R02182 N-acyl-D-aspartate amidohydrolase; N-Acyl-D-aspartate + H2O <=> Carboxylate + D-Aspartate R02183 UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl transferase; UDP-N-acetyl-D-galactosamine + Polypeptide <=> UDP + N-Acetyl-alpha-D-galactosaminyl-polypeptide R02184 ATP:polyphosphate phosphotransferase; ATP + Polyphosphate <=> ADP + Polyphosphate R02185 polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + D-Glucose <=> Polyphosphate + D-Glucose 6-phosphate R02186 dolichyl-diphosphate:polyphosphate phosphotransferase; Dolichyl diphosphate + Polyphosphate <=> Dolichyl phosphate + Polyphosphate R02187 polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + beta-D-Glucose <=> Polyphosphate + beta-D-Glucose 6-phosphate R02188 3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase; 3-Phospho-D-glyceroyl phosphate + Polyphosphate <=> 3-Phospho-D-glycerate + Polyphosphate R02189 polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + alpha-D-Glucose <=> Polyphosphate + alpha-D-Glucose 6-phosphate R02190 N -carbamoyl-D-amino acid amidohydrolase; N-Carbamoyl-D-amino acid + H2O <=> D-Amino acid + Ammonia + CO2 R02191 acetyl-CoA:D-amino-acid N-acetyltransferase; Acetyl-CoA + D-Amino acid <=> CoA + N-Acetyl-D-amino acid R02192 N-acyl-D-amino acid amidohydrolase; N-Acyl-D-amino acid + H2O <=> Carboxylate + D-Amino acid R02193 coniferyl aldehyde:NADP+ oxidoreductase (CoA-feruloylating); Coniferyl aldehyde + CoA + NADP+ <=> Feruloyl-CoA + NADPH + H+ R02194 ferulate:CoA ligase (AMP-forming); ATP + Ferulate + CoA <=> AMP + Diphosphate + Feruloyl-CoA R02195 feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase; Feruloyl-CoA + Quinate <=> CoA + 5-O-Feruloylquinic acid R02196 L-isoleucine:NAD+ oxidoreductase(deaminating); L-Isoleucine + NAD+ + H2O <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + NADH + H+ R02197 L-isoleucine:oxygen oxidoreductase (deaminating); L-Isoleucine + H2O + Oxygen <=> (S)-3-Methyl-2-oxopentanoic acid + Ammonia + Hydrogen peroxide R02199 L-isoleucine:2-oxoglutarate aminotransferase; L-Isoleucine + 2-Oxoglutarate <=> (S)-3-Methyl-2-oxopentanoic acid + L-Glutamate R02200 valine:(S)-3-methyl-2-oxopentanoate aminotransferase; L-Valine + (S)-3-Methyl-2-oxopentanoic acid <=> 3-Methyl-2-oxobutanoic acid + L-Isoleucine R02201 L-pipecolate:NAD+ 2-oxidoreductase; L-Pipecolate + NAD+ <=> Delta1-Piperideine-2-carboxylate + NADH + H+ R02203 L-pipecolate:NADP+ 2-oxidoreductase; L-Pipecolate + NADP+ <=> Delta1-Piperideine-2-carboxylate + NADPH + H+ R02204 L-pipecolate:oxygen 1,6-oxidoreductase; L-Pipecolate + Oxygen <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + Hydrogen peroxide R02205 L-pipecolate:(acceptor) 1,6-oxidoreductase; L-Pipecolate + FAD <=> FADH2 + (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate R02206 L-pipecolate:(acceptor) 1,6-oxidoreductase; L-Pipecolate + Acceptor <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + Reduced acceptor R02207 20alpha-hydroxy-4-pregnen-3-one:NAD+ 20-oxidoreductase; 20alpha-Hydroxy-4-pregnen-3-one + NAD+ <=> Progesterone + NADH + H+ R02208 5alpha-pregnane-3,20-dione:NADP+ delta4-oxidoreductase; 5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+ R02209 20alpha-hydroxy-4-pregnen-3-one:NADP+ 20-oxidoreductase; 20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+ R02210 ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing); Progesterone + Oxygen + NADPH + H+ <=> Testosterone acetate + NADP+ + H2O R02211 progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxyprogesterone + [Oxidized NADPH---hemoprotein reductase] + H2O R02212 progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating); Progesterone + Reduced acceptor + Oxygen <=> Testosterone acetate + Acceptor + H2O R02213 progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O R02214 progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating); Progesterone + Reduced acceptor + Oxygen <=> 11alpha-Hydroxyprogesterone + Acceptor + H2O R02215 5beta-pregnane-3,20-dione:(acceptor) delta4-oxidoreductase; 5beta-Pregnane-3,20-dione + Acceptor <=> Progesterone + Reduced acceptor R02216 pregnenolone:NAD+ 3-oxidoreductase; Pregnenolone + NAD+ <=> Progesterone + NADH + H+ R02218 progesterone,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating); Progesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta-Hydroxyprogesterone + 2 Oxidized ferredoxin + H2O R02219 3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase; 3-oxo-5beta-steroid: (acceptor) delta4-oxidoreductase; Progesterone + NADPH + H+ <=> 5beta-Pregnane-3,20-dione + NADP+ R02220 sinapoyl aldehyde:NADP+ oxidoreductase (CoA-sinapoylating); Sinapoyl aldehyde + CoA + NADP+ <=> Sinapoyl-CoA + NADPH + H+ R02221 sinapate:CoA ligase (AMP-forming); ATP + Sinapate + CoA <=> AMP + Diphosphate + Sinapoyl-CoA R02222 steroyl-CoA,hydrogen-donor:oxygen oxidoreductase; Stearoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Oleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R02224 stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing); Stearoyl-CoA + Malonyl-CoA + 2 NADPH + 2 H+ <=> Eicosanoyl-CoA + CO2 + 2 NADP+ + CoA + H2O R02225 ATP:streptomycin 6-phosphotransferase; ATP + Streptomycin <=> ADP + Streptomycin 6-phosphate R02226 ATP:streptomycin 3''-adenylyltransferase; ATP + Streptomycin <=> Diphosphate + 3''-Adenylylstreptomycin R02227 ATP:streptomycin 3''-phosphotransferase; ATP + Streptomycin <=> ADP + Streptomycin 3''-phosphate R02228 streptomycin-6-phosphate phosphohydrolase; Streptomycin 6-phosphate + H2O <=> Streptomycin + Orthophosphate R02229 cyclohexanol:NAD+ oxidoreductase; Cyclohexanone + NADH + H+ <=> Cyclohexanol + NAD+ R02231 cyclohexanone,NADPH:oxygen oxidoreductase (6-hydroxylating 1,2-lactonizing); Cyclohexanone + Oxygen + NADPH + H+ <=> epsilon-Caprolactone + NADP+ + H2O R02232 (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase; (1-Hydroxycyclohexan-1-yl)acetyl-CoA <=> Acetyl-CoA + Cyclohexanone R02233 cyclohexylamine:oxygen oxidoreductase (deaminating); Cyclohexylamine + Oxygen + H2O <=> Cyclohexanone + Hydrogen peroxide + Ammonia R02234 cyclohexanone:(acceptor) 2-oxidoreductase; Cyclohexanone + Acceptor <=> Cyclohex-2-enone + Reduced acceptor R02235 dihydrofolate:NAD+ oxidoreductase; Dihydrofolate + NAD+ <=> Folate + NADH + H+ R02236 dihydrofolate:NADP+ oxidoreductase; Dihydrofolate + NADP+ <=> Folate + NADPH + H+ R02237 7,8-dihydropteroate:L-glutamate ligase (ADP-forming); ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate R02238 formate:dihydrofolate ligase (ADP-forming); ATP + Formate + Dihydrofolate <=> ADP + Orthophosphate + 10-Formyldihydrofolate R02239 1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase; Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate R02240 ATP:1,2-diacylglycerol 3-phosphotransferase; ATP + 1,2-Diacyl-sn-glycerol <=> ADP + Phosphatidate R02241 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase; Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA R02242 acyl-CoA:2-acyl-sn-glycerol-3-phosphate O-acyltransferase; Acyl-CoA + 2-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate R02243 cis-aconitate carboxy-lyase; cis-Aconitate <=> Itaconate + CO2 R02244 trans-aconitate delta2-delta3-isomerase; trans-Aconitate <=> cis-Aconitate R02245 ATP:(R)-mevalonate 5-phosphotransferase; ATP + (R)-Mevalonate <=> ADP + (R)-5-Phosphomevalonate R02246 (R)-mevalonate:NAD+ oxidoreductase; (R)-Mevalonate + NAD+ <=> Mevaldate + NADH + H+ R02247 (R)-mevalonate:NADP+ oxidoreductase; (R)-Mevalonate + NADP+ <=> Mevaldate + NADPH + H+ R02248 polynucleotide 3'-phosphohydrolase; 3'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate R02249 5'-phosphopolynucleotide 5'-phosphohydrolase; 5'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate R02250 triacylglycerol acylhydrolase; Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid R02251 acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase; Triacylglycerol + CoA <=> 1,2-Diacyl-sn-glycerol + Acyl-CoA R02252 phenylpropanoate:NAD+ delta2-oxidoreductase; Phenylpropanoate + NAD+ <=> trans-Cinnamate + NADH + H+ R02253 trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating); trans-Cinnamate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Coumarate + [Oxidized NADPH---hemoprotein reductase] + H2O R02254 trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating); trans-Cinnamate + Oxygen + NADPH + H+ <=> trans-2-Hydroxycinnamate + NADP+ + H2O R02255 trans-cinnamate:CoA ligase (AMP-forming); ATP + trans-Cinnamate + CoA <=> AMP + Diphosphate + Cinnamoyl-CoA R02256 UDPglucose:trans-cinnamate beta-D-glucosyltransferase; UDP-glucose + trans-Cinnamate <=> UDP + trans-Cinnamoyl beta-D-glucoside R02257 propane-1,2-diol:NAD+ oxidoreductase; Propane-1,2-diol + NAD+ <=> (S)-Lactaldehyde + NADH + H+ R02258 (S)-propane-1,2-diol:NAD+ oxidoreductase; (S)-Propane-1,2-diol + NAD+ <=> (S)-Lactaldehyde + NADH + H+ R02259 propane-1,2-diol:NADP+ oxidoreductase; Propane-1,2-diol + NADP+ <=> (S)-Lactaldehyde + NADPH + H+ R02260 (S)-lactaldehyde:NADP+ oxidoreductase; (S)-Lactaldehyde + NADP+ <=> Methylglyoxal + NADPH + H+ R02261 2-dehydro-3-deoxy-L-rhamnonate (S)-lactaldehyde lyase (pyruvate-forming); 2-Dehydro-3-deoxy-L-rhamnonate <=> (S)-Lactaldehyde + Pyruvate R02262 L-fuculose-1-phosphate lactaldehyde-lyase; L-Fuculose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde R02263 L-rhamnulose-1-phosphate lactaldehyde-lyase; L-Rhamnulose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde R02264 Prostaglandin H2 + NADPH + H+ <=> Prostaglandin F2alpha + NADP+ R02265 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase; Prostaglandin H2 <=> Prostaglandin E2 R02266 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate D-isomerase; Prostaglandin H2 <=> Prostaglandin D2 R02267 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase; Prostaglandin H2 <=> Prostaglandin I2 R02268 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-thromboxane-A2-isomerase; Prostaglandin H2 <=> Thromboxane A2 R02269 5,6-dihydrouracil amidohydrolase; 5,6-Dihydrouracil + H2O <=> 3-Ureidopropionate R02271 5-aminolevulinate:pyruvate aminotransferase; 5-Aminolevulinate + Pyruvate <=> 4,5-Dioxopentanoate + L-Alanine R02272 (S)-4-amino-5-oxopentanoate 4,5-aminomutase; 5-Aminolevulinate <=> (S)-4-Amino-5-oxopentanoate R02273 5-aminopentanamide amidohydrolase; 5-Aminopentanamide + H2O <=> 5-Aminopentanoate + Ammonia R02274 5-aminopentanoate:2-oxoglutarate aminotransferase; 5-Aminopentanoate + 2-Oxoglutarate <=> 5-Oxopentanoate + L-Glutamate R02276 5-acetamidopentanoate amidohydrolase; 5-Acetamidopentanoate + H2O <=> Acetate + 5-Aminopentanoate R02277 secondary-alcohol:oxygen oxidoreductase; Secondary alcohol + Oxygen <=> Ketone + Hydrogen peroxide R02278 2-dehydro-3-deoxy-L-arabinonate hydro-lyase; 2-Dehydro-3-deoxy-L-arabinonate <=> 2,5-Dioxopentanoate + H2O R02279 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating); 5-Dehydro-4-deoxy-D-glucarate <=> 2,5-Dioxopentanoate + H2O + CO2 R02280 1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing); 1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2,5-Dioxopentanoate + Ammonia R02281 alkane,reduced-rubredoxin:oxygen 1-oxidoreductase; Alkane + 2 Reduced rubredoxin + Oxygen + 2 H+ <=> 2 Oxidized rubredoxin + Primary alcohol + H2O R02282 N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase; N-Acetylornithine + L-Glutamate <=> L-Ornithine + N-Acetyl-L-glutamate R02283 N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase; N-Acetylornithine + 2-Oxoglutarate <=> N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate R02284 L-5-carboxymethylhydantoin amidohydrolase; L-5-Carboxymethylhydantoin + H2O <=> N-Carbamoyl-L-aspartate R02285 N-formimino-L-glutamate formiminohydrolase; N-Formimino-L-glutamate + H2O <=> L-Glutamate + Formamide R02286 N-formimino-L-glutamate iminohydrolase; N-Formimino-L-glutamate + H2O <=> N-Formyl-L-glutamate + Ammonia R02287 5-formiminotetrahydrofolate:L-glutamate N-formiminotransferase; 5-Formiminotetrahydrofolate + L-Glutamate <=> Tetrahydrofolate + N-Formimino-L-glutamate R02288 4-imidazolone-5-propanoate amidohydrolase; 4-Imidazolone-5-propanoate + H2O <=> N-Formimino-L-glutamate R02289 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; [methyl-Co(III) glycine betaine-specific corrinoid protein]:tetrahydrofolate N-methyltransferase; 5-Methyltetrahydrofolate + Co(I) corrinoid protein + H+ <=> Methyl-Co(III) corrinoid protein + Tetrahydrofolate R02291 L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating); L-Aspartate 4-semialdehyde + Orthophosphate + NADP+ <=> 4-Phospho-L-aspartate + NADPH + H+ R02293 L-2,4-diaminobutanoate:pyruvate aminotransferase; L-2,4-Diaminobutanoate + Pyruvate <=> L-Aspartate 4-semialdehyde + L-Alanine R02294 N-ribosylnicotinamide:orthophosphate ribosyltransferase; Nicotinamide-beta-riboside + Orthophosphate <=> Nicotinamide + alpha-D-Ribose 1-phosphate R02295 nicotinate D-ribonucleoside:orthophosphate ribosyltransferase; Nicotinate D-ribonucleoside + Orthophosphate <=> Nicotinate + alpha-D-Ribose 1-phosphate + H+ R02296 cytidine:orthophosphate alpha-D-ribosyltransferase; Cytidine + Orthophosphate <=> Cytosine + alpha-D-Ribose 1-phosphate R02297 xanthosine:orthophosphate ribosyltransferase; Xanthosine + Orthophosphate <=> Xanthine + alpha-D-Ribose 1-phosphate R02298 pyrimidine-nucleoside:orthophosphate alpha-D-ribosyltransferase; Pyrimidine nucleoside + Orthophosphate <=> Pyrimidine + alpha-D-Ribose 1-phosphate + H+ R02300 S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming); Folinic acid <=> 5,10-Methenyltetrahydrofolate + H2O R02301 5-formyltetrahydrofolate cyclo-ligase (ADP-forming); ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate R02302 5-formiminotetrahydrofolate ammonia-lyase (cyclizing); 5-Formiminotetrahydrofolate + H+ <=> 5,10-Methenyltetrahydrofolate + Ammonia R02303 ATP:farnesyl-diphosphate phosphotransferase; ATP + trans,trans-Farnesyl diphosphate <=> ADP + Farnesyl triphosphate R02305 2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming); trans,trans-Farnesyl diphosphate <=> Pentalenene + Diphosphate R02306 trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming); trans,trans-Farnesyl diphosphate <=> Trichodiene + Diphosphate R02307 trans,trans-farnesyl-diphosphate farnesyltransferase (bicyclizing); trans,trans-Farnesyl diphosphate <=> Aristolochene + Diphosphate R02310 trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase (isomerizing); trans,trans-Farnesyl diphosphate <=> Nerolidyl diphosphate R02311 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming); trans,trans-Farnesyl diphosphate <=> delta-Cadinene + Diphosphate R02313 N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming); N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H+ R02315 N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADPH + H+ R02317 (S)-2-amino-6-oxohexanoate hydro-lyase (spontaneous); (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O <=> L-2-Aminoadipate 6-semialdehyde R02318 (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase; (1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate <=> (1S,2S)-1-Hydroxypropane-1,2,3-tricarboxylate R02319 NTP phosphohydrolase; Nucleoside triphosphate + H2O <=> NDP + Orthophosphate R02320 NTP:pyruvate O2-phosphotransferase; Nucleoside triphosphate + Pyruvate <=> NDP + Phosphoenolpyruvate R02321 NTP:deoxycitidine 5'-phosphotransferase; Nucleoside triphosphate + Deoxycytidine <=> NDP + dCMP R02322 nicotinamide-D-ribonucleotide amidohydrolase; Nicotinamide D-ribonucleotide + H2O <=> Nicotinate D-ribonucleotide + Ammonia R02323 nicotinamide ribonucleotide phosphohydrolase; Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate R02324 ATP:N-ribosylnicotinamide 5'-phosphotransferase; ATP + Nicotinamide-beta-riboside <=> ADP + Nicotinamide D-ribonucleotide R02325 dCTP aminohydrolase; dCTP + H2O <=> dUTP + Ammonia R02326 ATP:dCDP phosphotransferase; ATP + dCDP <=> ADP + dCTP R02328 dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase; dTTP + D-Glucose 1-phosphate <=> Diphosphate + dTDP-glucose R02329 dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase; dTTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + dTDP-galactose R02330 dUTP nucleotidohydrolase; dUTP + H2O <=> dUDP + Orthophosphate R02331 ATP:dUDP phosphotransferase; ATP + dUDP <=> ADP + dUTP R02333 chitin amidohydrolase; Chitin + n H2O <=> Chitosan + n Acetate R02334 [1,4-(N-acetyl-beta-D-glucosaminyl)]n glycanohydrolase; Chitin + H2O <=> Chitobiose + Chitin R02335 UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase; UDP-N-acetyl-alpha-D-glucosamine + Chitin <=> UDP + Chitin R02336 haloacetate halidohydrolase; Haloacetate + H2O <=> Glycolate + Halide R02337 1-haloalkane halidohydrolase; 1-Haloalkane + H2O <=> Primary alcohol + Halide R02338 indole:oxygen 2,3-oxidoreductase (decyclizing); Indole + Oxygen <=> 2-Formylaminobenzaldehyde R02339 Indole + Oxygen + NADPH + H+ <=> Indoxyl + H2O + NADP+ R02340 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase; Indoleglycerol phosphate <=> Indole + D-Glyceraldehyde 3-phosphate R02341 N-D-ribosylpurine ribohydrolase; N-D-Ribosylpurine + H2O <=> Purine + D-Ribose R02343 acetoin:NAD+ oxidoreductase; Acetoin + NAD+ <=> Diacetyl + NADH + H+ R02344 (S,S)-butane-2,3-diol:NAD+ oxidoreductase; (S,S)-Butane-2,3-diol + NAD+ <=> Acetoin + NADH + H+ R02345 3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase; Acetoin + D-Ribose 5-phosphate <=> Acetaldehyde + 1-Deoxy-D-altro-heptulose 7-phosphate R02347 estradiol-17alpha:NAD+ 17-oxidoreductase; Estradiol-17alpha + NAD+ <=> Estrone + NADH + H+ R02349 estradiol-17alpha:NADP+ 16-oxidoreductase; Estradiol-17alpha + NADP+ <=> Estrone + NADPH + H+ R02350 3'-phosphoadenylylsulfate:estrone 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Estrone <=> Adenosine 3',5'-bisphosphate + Estrone 3-sulfate R02351 19-oxoandrostenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (aromatizing, formate-forming); 19-Oxoandrost-4-ene-3,17-dione + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Estrone + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O R02352 estradiol-17beta:NAD+ 17-oxidoreductase; Estradiol-17beta + NAD+ <=> Estrone + NADH + H+ R02353 estradiol-17beta:NADP+ 17-oxidoreductase; Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+ R02354 Estrone + H+ + Oxygen + NADH <=> 2-Hydroxyestrone + NAD+ + H2O R02355 Estrone + H+ + Oxygen + NADPH <=> 2-Hydroxyestrone + NADP+ + H2O R02356 Estrone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxyestrone + NADP+ + H2O R02358 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); Estrone + UDP-glucuronate <=> Estrone glucuronide + UDP R02359 urethane amidohydrolase (decarboxylating); Urethane + H2O <=> Ethanol + CO2 + Ammonia R02360 poly(1,4-alpha-D-galacturonate) glycanohydrolase; Pectate + H2O <=> Digalacturonate + Pectate R02361 (1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase; Pectate <=> 4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate + Pectate R02362 pectin pectylhydrolase; Pectin + n H2O <=> n Methanol + Pectate R02363 hydroquinone:oxygen oxidoreductase; 2 Hydroquinone + Oxygen <=> 2 p-Benzoquinone + 2 H2O R02364 NADPH2:quinone oxidoreductase; 2 Quinone + NADPH + H+ <=> 2 Semiquinone + NADP+ R02365 cellobiose:quinone 1-oxidoreductase; Cellobiose + Quinone <=> Cellobiono-1,5-lactone + Hydroquinone R02366 acyl-CoA:retinol O-acyltransferase; Acyl-CoA + Retinol <=> CoA + Retinyl ester R02367 palmitoyl-CoA:retinol O-acyltransferase; Palmitoyl-CoA + Retinol <=> CoA + Retinyl palmitate R02368 retinyl-palmitate palmitohydrolase; Retinyl palmitate + H2O <=> Retinol + Hexadecanoic acid R02369 all-trans-retinol 11-cis-trans-isomerase; Retinol <=> 11-cis-Retinol R02370 cytidine 3'-phosphate phosphohydrolase; 3'-CMP + H2O <=> Cytidine + Orthophosphate R02373 ecdysone:oxygen 3-oxidoreductase; Ecdysone + Oxygen <=> 3-Dehydroecdysone + Hydrogen peroxide R02374 ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating); Ecdysone + Reduced acceptor + Oxygen <=> 20-Hydroxyecdysone + Acceptor + H2O R02375 palmitoyl-CoA:ecdysone O-palmitoyltransferase; Palmitoyl-CoA + Ecdysone <=> CoA + Ecdysone palmitate R02376 propane-1,2-diol hydro-lyase; Propane-1,2-diol <=> Propanal + H2O R02377 propane-1,3-diol:NAD+ 1-oxidoreductase; Propane-1-ol + NAD+ <=> Propanal + NADH + H+ R02378 L-serine hydro-lyase (adding pyrazole); L-Serine + Pyrazole <=> 3-(Pyrazol-1-yl)-L-alanine + H2O R02379 S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; S-Adenosyl-L-methionine + 5-Hydroxyferulic acid <=> S-Adenosyl-L-homocysteine + Sinapate R02380 UDPglucose:sinapate D-glucosyltransferase; UDP-glucose + Sinapate <=> UDP + 1-O-Sinapoyl-beta-D-glucose R02381 sinapoylcholine sinapohydrolase; Sinapine + H2O <=> Sinapate + Choline R02382 tyramine:oxygen oxidoreductase(deaminating)(flavin-containing); Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide R02383 monophenol,L-dopa:oxygen oxidoreductase; Tyramine + Oxygen + NADH + H+ <=> Dopamine + NAD+ + H2O R02384 S-adenosyl-L-methionine:tyramine N-methyltransferase; S-Adenosyl-L-methionine + Tyramine <=> S-Adenosyl-L-homocysteine + N-Methyltyramine R02385 feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase; Feruloyl-CoA + Tyramine <=> CoA + N-Feruloyltyramine R02387 acetyl-CoA:arylamine N-acetyltransferase; Acetyl-CoA + Aniline <=> CoA + Acetanilide R02388 UDPglucose:arylamine N-D-glucosyltransferase; UDP-glucose + Aniline <=> UDP + N-D-Glucosylarylamine R02389 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); 2 UDP-glucuronate + Bilirubin <=> 2 UDP + Bilirubin beta-diglucuronide R02391 bilirubin:NAD+ oxidoreductase; Bilirubin + NAD+ <=> Biliverdin + NADH + H+ R02393 bilirubin:NADP+ oxidoreductase; Bilirubin + NADP+ <=> Biliverdin + NADPH + H+ R02394 bilirubin:oxygen oxidoreductase; 2 Bilirubin + Oxygen <=> 2 Biliverdin + 2 H2O R02395 carnitine:NAD+ 3-oxidoreductase; Carnitine + NAD+ <=> 3-Dehydrocarnitine + NADH + H+ R02396 acetyl-CoA:carnitine O-acetyltransferase; Acetyl-CoA + Carnitine <=> CoA + O-Acetylcarnitine R02397 4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); 4-Trimethylammoniobutanoate + 2-Oxoglutarate + Oxygen <=> Carnitine + Succinate + CO2 R02398 carnitine carboxy-lyase; Carnitine <=> 2-Methylcholine + CO2 R02401 glutarate-semialdehyde:NAD+ oxidoreductase; 5-Oxopentanoate + NAD+ + H2O <=> Glutarate + NADH + H+ R02402 glutarate:CoA ligase (ADP-forming); ATP + Glutarate + CoA <=> ADP + Orthophosphate + Glutaryl-CoA R02404 itaconate:CoA ligase (ADP-forming); ATP + Itaconate + CoA <=> ADP + Orthophosphate + Itaconyl-CoA R02405 itaconate:CoA ligase (GDP-forming); GTP + Itaconate + CoA <=> GDP + Orthophosphate + Itaconyl-CoA R02406 itaconate:CoA ligase (IDP-forming); ITP + Itaconate + CoA <=> IDP + Orthophosphate + Itaconyl-CoA R02407 succinyl-CoA:itaconate CoA-transferase; Succinyl-CoA + Itaconate <=> Succinate + Itaconyl-CoA R02408 L-cystine thiocysteine-lyase (deaminating; pyruvate-forming); L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine R02409 coenzyme A:oxidized-glutathione oxidoreductase; L-Cystine + Sulfate <=> S-Sulfo-L-cysteine + L-Cysteine R02410 raffinose fructohydrolase; Raffinose + H2O <=> Melibiose + D-Fructose R02411 1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase; alpha-D-Galactosyl-(1->3)-1D-myo-inositol + Sucrose <=> myo-Inositol + Raffinose R02412 ATP:shikimate 3-phosphotransferase; ATP + Shikimate <=> ADP + Shikimate 3-phosphate R02413 shikimate:NADP+ 3-oxidoreductase; Shikimate + NADP+ <=> 3-Dehydroshikimate + NADPH + H+ R02415 shikimate:pyrroloquinoline-quinone 3-oxidoreductase; Shikimate + PQQ <=> 3-Dehydroshikimate + PQQH2 R02416 4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase; p-Coumaroyl-CoA + Shikimate <=> CoA + 4-Coumaroylshikimate R02417 questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening); Questin + Oxygen + NADPH + H+ <=> Demethylsulochrin + NADP+ R02418 ubiquitin-C-terminal-thiolester hydrolase; Ubiquitin C-terminal thiolester + H2O <=> Ubiquitin + Thiol R02419 (R)-malate hydro-lyase; (R)-Malate <=> Maleic acid + H2O R02420 ADPglucose:protein 4-alpha-D-glucosyltransferase; ADP-glucose + Protein <=> ADP + alpha-D-Glucosyl-protein R02421 ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase; ADP-glucose + Amylose <=> ADP + Amylose R02422 allantoate amidinohydrolase; Allantoate + H2O <=> (S)-Ureidoglycolate + Urea R02423 allantoate amidinohydrolase (decarboxylating); Allantoate + H2O <=> (S)-Ureidoglycine + Ammonia + CO2 R02425 (S)-allantoin amidohydrolase; (S)-Allantoin + H2O <=> Allantoate R02426 CDPglucose 4,6-hydro-lyase; CDP-glucose <=> CDP-4-dehydro-6-deoxy-D-glucose + H2O R02427 D-xylono-1,5-lactone lactonohydrolase; D-Xylonolactone + H2O <=> D-Xylonate R02428 D-xylono-1,4-lactone lactonohydrolase; D-Xylono-1,4-lactone + H2O <=> D-Xylonate R02429 D-xylonate hydro-lyase; D-Xylonate <=> 2-Dehydro-3-deoxy-D-xylonate + H2O R02430 ATP:erythritol 4-phosphotransferase; ATP + Erythritol <=> ADP + D-Erythritol 4-phosphate R02432 NTP:gentamicin 2''-nucleotidyltransferase; Nucleoside triphosphate + Gentamicin <=> Diphosphate + 2''-Nucleotidylgentamicin R02433 L-cysteate:2-oxoglutarate aminotransferase; L-Cysteate + 2-Oxoglutarate <=> 3-Sulfopyruvate + L-Glutamate R02434 L-Cysteate + NADH + H+ <=> 3-Sulfino-L-alanine + H2O + NAD+ R02436 quercitrin 3-L-rhamnohydrolase; Quercitrin + H2O <=> L-Rhamnose + Quercetin R02437 L-rhamnose ketol-isomerase; L-Rhamnose <=> L-Rhamnulose R02438 L-Rhamnose <=> L-Rhamnofuranose R02439 ATP:L-ribulose 5-phosphotransferase; ATP + L-Ribulose <=> ADP + L-Ribulose 5-phosphate R02441 L-arabitol:NAD+ 2-oxidoreductase (L-ribulose-forming); L-Arabitol + NAD+ <=> L-Ribulose + NADH + H+ R02442 naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O R02443 naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Naringenin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Pentahydroxyflavanone + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R02444 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Naringenin + 2-Oxoglutarate + Oxygen <=> Dihydrokaempferol + Succinate + CO2 R02445 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Naringenin + 2-Oxoglutarate + Oxygen <=> Apigenin + Succinate + CO2 + H2O R02446 flavanone lyase (decyclizing); Naringenin <=> Naringenin chalcone R02447 malonyl-CoA:benzoyl-CoA malonyltransferase (2,4,6-trihydroxybenzophenone-forming); 3 Malonyl-CoA + Benzoyl-CoA <=> 4 CoA + 2,4,6-Trihydroxybenzophenone + 3 CO2 R02449 benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating); Benzoyl-CoA + Oxygen + NADPH + H+ <=> 3-Hydroxybenzoyl-CoA + NADP+ + H2O R02450 phenylglyoxylate:NAD+ oxidoreductase (CoA benzoylating); alpha-Oxo-benzeneacetic acid + CoA + NAD+ <=> Benzoyl-CoA + CO2 + NADH + H+ R02451 cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming); Benzoyl-CoA + Reduced ferredoxin + 2 ATP + 2 H2O <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Oxidized ferredoxin + 2 Orthophosphate + 2 ADP R02452 benzoyl-CoA:glycine N-benzoyltransferase; Benzoyl-CoA + Glycine <=> CoA + Hippurate R02453 benzoyl-CoA:anthranilate N-benzoyltransferase; Benzoyl-CoA + Anthranilate <=> CoA + N-Benzoylanthranilate R02454 D-mannonate:NAD+ 5-oxidoreductase; D-Mannonate + NAD+ <=> D-Fructuronate + NADH + H+ R02455 D-mannonate:NAD+ 6-oxidoreductase; D-Mannonate + NAD+ <=> D-Mannuronate + NADH + H+ R02456 D-mannonate:NADP+ 6-oxidoreductase; D-Mannonate + NADP+ <=> D-Mannuronate + NADPH + H+ R02457 D-ornithine:oxygen oxidoreductase (deaminating); D-Ornithine + H2O + Oxygen <=> 5-Amino-2-oxopentanoic acid + Ammonia + Hydrogen peroxide R02458 D-arginine amidinohydrolase; D-Arginine + H2O <=> D-Ornithine + Urea R02459 D-ornithine:2-oxoglutarate aminotransferase; D-Ornithine + 2-Oxo acid <=> 5-Amino-2-oxopentanoic acid + D-Amino acid R02460 bacitracin synthetase 2; D-Ornithine <=> Bacitracin R02461 D-ornithine 4,5-aminomutase; D-Ornithine <=> (2R,4S)-2,4-Diaminopentanoate R02462 hexadecanol:NAD+ oxidoreductase; 1-Hexadecanol + NAD+ <=> Hexadecanal + NADH + H+ R02463 hexadecanal:NADP+ delta2-oxidoreductase; Hexadecanal + NADP+ <=> Hexadecenal + NADPH + H+ R02464 sphinganine-1-phosphate pamlmitaldehyde-lyase; Sphinganine 1-phosphate <=> Ethanolamine phosphate + Hexadecanal R02465 hyaluronate lyase; Hyaluronate <=> n 3-(4-Deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine R02466 3-sulfino-L-alanine carboxy-lyase; 3-Sulfino-L-alanine <=> Hypotaurine + CO2 R02467 cysteamine:oxygen oxidoreductase; Cysteamine + Oxygen <=> Hypotaurine R02468 (S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating); (S)-Limonene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (-)-trans-Carveol + [Oxidized NADPH---hemoprotein reductase] + H2O R02469 (S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); (S)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-trans-Isopiperitenol + [Oxidized NADPH---hemoprotein reductase] + H2O R02470 (S)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating); (S)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Perillyl alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O R02471 (R)-Pantoate + NAD+ <=> (R)-4-Dehydropantoate + NADH + H+ R02472 (R)-pantoate:NADP+ 2-oxidoreductase; (R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+ R02473 (R)-pantoate:beta-alanine ligase (AMP-forming); ATP + (R)-Pantoate + beta-Alanine <=> AMP + Diphosphate + Pantothenate R02474 pantothenate amidohydrolase; Pantothenate + H2O <=> (R)-Pantoate + beta-Alanine R02476 androsterone:NAD+ oxidoreductase; Androsterone + NAD+ <=> 5alpha-Androstane-3,17-dione + NADH + H+ R02477 androsterone:NADP+ oxidoreductase; Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+ R02478 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); Androsterone + UDP-glucuronate <=> Androsterone glucuronide + UDP R02480 cytochrome c apocytochrome-c-lyase; Cytochrome c <=> Apocytochrome c + Heme R02481 acetyl-CoA:D-tryptophan N-acetyltransferase; Acetyl-CoA + D-Tryptophan <=> CoA + N-Acetyl-D-tryptophan R02482 malonyl-CoA:D-tryptophan N-malonyltransferase; Malonyl-CoA + D-Tryptophan <=> CoA + N2-Malonyl-D-tryptophan R02484 deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase; deoxyuridine:orthophosphate ribosyltransferase; Deoxyuridine + Orthophosphate <=> Uracil + 2-Deoxy-D-ribose 1-phosphate R02485 deoxycytidine aminohydrolase; Deoxycytidine + H2O <=> Deoxyuridine + Ammonia R02486 2-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating); Deoxyuridine + 2-Oxoglutarate + Oxygen <=> Deoxyribonolactone + Uracil + Succinate + CO2 R02487 glutaryl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase (decarboxylating); Glutaryl-CoA + FAD <=> FADH2 + Crotonoyl-CoA + CO2 R02488 glutaryl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase (decarboxylating); Glutaryl-CoA + Electron-transferring flavoprotein <=> Crotonoyl-CoA + Reduced electron-transferring flavoprotein + CO2 R02489 gentisate carboxy-lyase; 2,5-Dihydroxybenzoate <=> Hydroquinone + CO2 R02490 citramalyl-CoA hydro-lyase; Citramalyl-CoA <=> Itaconyl-CoA + H2O R02491 (3S)-citramalyl-CoA hydro-lyase (itaconyl-CoA-forming); (3S)-Citramalyl-CoA <=> Itaconyl-CoA + H2O R02492 nitrous-oxide:NAD+ oxidoreductase; 2 Nitric oxide + NADH + H+ <=> Nitrous oxide + NAD+ + H2O R02493 ATP:pyridoxal 5'-phosphotransferase; ATP + Pyridoxamine <=> ADP + Pyridoxamine phosphate R02494 pyridoxamine-5'-phosphate phosphohydrolase; Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O R02497 dihydrotestosterone:NADP+ delta4-oxidoreductase; Dihydrotestosterone + NADP+ <=> Testosterone + NADPH + H+ R02498 5beta-dihydrotestosterone:NADP+ 4,5-oxidoreductase; 5beta-Dihydrotestosterone + NADP+ <=> Testosterone + NADPH + H+ R02499 testosterone delta5-delat4-isomerase; androst-5-ene-3beta,17beta-diol:NAD+ 3-oxidoreductase; Testosterone + H+ + NADH <=> Androstenediol + NAD+ R02501 testosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (19-hydroxylating); Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O R02502 17beta-hydroxysteroid UDP-glucuronosyltransferase; Testosterone + UDP-glucuronate <=> Testosterone glucuronide + UDP R02503 testosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating); Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O R02504 trimetaphosphate hydrolase; Trimetaphosphoric acid + H2O <=> Triphosphate R02505 malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing); 3 Malonyl-CoA + Cinnamoyl-CoA <=> 4 CoA + Pinosylvin + 4 CO2 R02506 cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating); Cinnamaldehyde + CoA + NADP+ <=> Cinnamoyl-CoA + NADPH + H+ R02508 Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine R02509 N,N-dimethylformamide amidohydrolase; N,N-Dimethylformamide + H2O <=> Dimethylamine + Formate R02511 trimethylamine:electron-transferring flavoprotein oxidoreductase(demethylating); Trimethylamine + H2O + Electron-transferring flavoprotein <=> Dimethylamine + Formaldehyde + Reduced electron-transferring flavoprotein R02512 trimethylamine-N-oxide formaldehyde-lyase; Trimethylamine N-oxide <=> Dimethylamine + Formaldehyde R02513 Nomega,Nomega'-dimethyl-L-arginine dimethylamidohydrolase; NG,NG-Dimethyl-L-arginine + H2O <=> Dimethylamine + L-Citrulline R02514 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (1-hydroxylating); 4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O R02515 3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (6-hydroxylating); 3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O R02516 4-hydroxyphenylacetate,NADPH:oxygen oxidoreductase (1-hydroxylating); 4-Hydroxyphenylacetate + Oxygen + NADPH + H+ <=> Homogentisate + NADP+ + H2O R02517 3-hydroxyphenylacetate,NADPH:oxygen oxidoreductase (6-hydroxylating); 3-Hydroxyphenylacetate + Oxygen + NADPH + H+ <=> Homogentisate + NADP+ + H2O R02518 Homogentisate + Oxygen + NADPH <=> Gentisate aldehyde + CO2 + NADP+ + H+ + H2O R02519 homogentisate:oxygen 1,2-oxidoreductase (decyclizing); Homogentisate + Oxygen <=> 4-Maleylacetoacetate R02520 Homogentisate + Oxygen <=> Gentisate aldehyde + CO2 + H2O R02521 4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating); 3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> Homogentisate + CO2 R02522 L-arabinonate hydro-lyase; L-Arabinonate <=> 2-Dehydro-3-deoxy-L-arabinonate + H2O R02526 L-arabinono-1,4-lactone lactonohydrolase; L-Arabinono-1,4-lactone + H2O <=> L-Arabinonate R02527 (R)-lactaldehyde:NAD+ oxidoreductase; (R)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+ R02528 Methylglyoxal + NADPH + H+ <=> Hydroxyacetone + NADP+ R02529 aminoacetone:oxygen oxidoreductase(deaminating); Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide R02530 (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing); (R)-S-Lactoylglutathione <=> Glutathione + Methylglyoxal R02531 lactaldehyde:NAD+ 1-oxidoreductase; Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+ R02532 4-[(1R)-2-amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing); L-Noradrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Ammonia + Hydrogen peroxide R02533 S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + L-Noradrenaline <=> S-Adenosyl-L-homocysteine + L-Adrenaline R02534 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + L-Noradrenaline <=> S-Adenosyl-L-homocysteine + L-Normetanephrine R02535 dopamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating); Dopamine + 2 Ascorbate + Oxygen <=> L-Noradrenaline + 2 Monodehydroascorbate + H2O R02536 phenylacetaldehyde:NAD+ oxidoreductase; Phenylacetaldehyde + NAD+ + H2O <=> Phenylacetic acid + NADH + H+ R02537 aldehyde:NADP+ oxidoreductase; Phenylacetaldehyde + NADP+ + H2O <=> Phenylacetic acid + NADPH + H+ R02539 phenylacetate:CoA ligase; ATP + Phenylacetic acid + CoA <=> AMP + Diphosphate + Phenylacetyl-CoA R02540 2-phenylacetamide amidohydrolase; 2-Phenylacetamide + H2O <=> Phenylacetic acid + Ammonia R02541 sphingomyelin cholinephosphohydrolase; Sphingomyelin + H2O <=> N-Acylsphingosine + Choline phosphate R02542 sphingomyelin ceramide-phosphohydrolase; Sphingomyelin + H2O <=> Choline + Ceramide 1-phosphate R02543 acyl-CoA:sphingosine N-acyltransferase; Acyl-CoA + Sphingosyl-phosphocholine <=> CoA + Sphingomyelin R02544 meso-tartrate:NAD+ oxidoreductase; meso-Tartaric acid + NAD+ <=> Dihydroxyfumarate + NADH + H+ R02545 meso-tartaric acid:NAD+ oxidoreductase; meso-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+ R02546 (R,R)-tartrate epimerase; (R,R)-Tartaric acid <=> meso-Tartaric acid R02547 trans-2,3-epoxysuccinate hydrolase; trans-2,3-Epoxysuccinate + H2O <=> meso-Tartaric acid R02548 (+)-neomenthol:NADP+ oxidoreductase; (+)-Neomenthol + NADP+ <=> (-)-Menthone + NADPH + H+ R02549 4-aminobutanal:NAD+ 1-oxidoreductase; 4-aminobutyraldehyde:NAD+ oxidoreductase; 4-Aminobutyraldehyde + NAD+ + H2O <=> 4-Aminobutanoate + NADH + H+ R02550 toluene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating); toluene/o-xylene monooxygenase; Benzyl alcohol + 2 Oxidized ferredoxin + H2O <=> Toluene + Oxygen + 2 Reduced ferredoxin + 2 H+ R02551 N-benzyloxycarbonylglycine urethanehydrolase; N-Benzyloxycarbonylglycine + H2O <=> Benzyl alcohol + CO2 + Glycine R02552 N(alpha)-benzyloxycarbonyl-L-leucine urethanehydrolase; N(alpha)-Benzyloxycarbonyl-L-leucine + H2O <=> Benzyl alcohol + CO2 + L-Leucine R02553 cyclopentanol:NAD+ oxidoreductase; Cyclopentanol + NAD+ <=> Cyclopentanone + NADH + H+ R02554 cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing); Cyclopentanone + Oxygen + NADPH + H+ <=> 5-Valerolactone + NADP+ + H2O R02555 D-altronate:NAD+ 3-oxidoreductase; D-Altronate + NAD+ <=> D-Tagaturonate + NADH + H+ R02556 deoxyadenosine aminohydrolase; Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia R02557 deoxyadenosine:orthophosphate ribosyltransferase; Deoxyadenosine + Orthophosphate <=> Adenine + 2-Deoxy-D-ribose 1-phosphate R02558 (R)-prunasin beta-D-glucohydrolase; Prunasin + H2O <=> Mandelonitrile + D-Glucose R02560 trimethylamine:cytochrome c oxidoreductase; Trimethylamine + 2 Ferricytochrome c + H2O <=> Trimethylamine N-oxide + 2 Ferrocytochrome c + 2 H+ R02561 4-aminobenzoate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 4-Aminobenzoate + Oxygen + NADH + H+ <=> 4-Hydroxyaniline + CO2 + NAD+ + H2O R02562 4-aminobenzoate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 4-Aminobenzoate + Oxygen + NADPH + H+ <=> 4-Hydroxyaniline + CO2 + NADP+ + H2O R02563 CDPethanolamine:L-serine ethanolaminephosphotransferase; CDP-ethanolamine + L-Serine <=> CMP + L-Serine-phosphoethanolamine R02564 cyclohexylsulfamate sulfohydrolase; Cyclohexylsulfamate + H2O <=> Cyclohexylamine + Sulfate R02565 p-cumic alcohol:NAD+ oxidoreductase; Betaine aldehyde + NAD+ + H2O <=> Betaine + NADH + 2 H+ R02566 p-cumic alcohol:NADP+ oxidoreductase; Betaine aldehyde + NADP+ + H2O <=> Betaine + NADPH + 2 H+ R02568 D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase; D-Fructose 1-phosphate <=> Glycerone phosphate + D-Glyceraldehyde R02569 acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase; Acetyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine R02570 succinyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-succinyltransferase; Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine R02571 glutaryl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-glutaryltransferase; Glutaryl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine R02572 S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase; S-Adenosyl-L-methionine + Dimethyl sulfide <=> S-Adenosyl-L-homocysteine + Trimethylsulfonium R02573 trimethylsulfonium:tetrahydrofolate N-methyltransferase; Trimethylsulfonium + Tetrahydrofolate <=> Dimethyl sulfide + 5-Methyltetrahydrofolate R02574 S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase; S,S-Dimethyl-beta-propiothetin <=> Dimethyl sulfide + Acrylic acid R02575 ATP:guanidoacetate N-phosphotransferase; ATP + Guanidinoacetate <=> ADP + Phosphoguanidinoacetate R02576 phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase; Phenylacetyl-CoA + L-Glutamine <=> CoA + Phenylacetylglutamine R02577 propane-1,2-diol:NADP+ 1-oxidoreductase; Propane-1,2-diol + NADP+ <=> Lactaldehyde + NADPH + H+ R02580 (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+15-oxidoreductase; Prostaglandin E2 + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+ R02581 (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase; prostaglandin F2alpha:NADP+ oxidoreductase; Prostaglandin F2alpha + NADP+ <=> Prostaglandin E2 + NADPH + H+ R02583 Prostaglandin E2 <=> Prostaglandin A2 + H2O R02584 ATP:[protein]-L-tyrosine O-phosphotransferase; ATP + Protein tyrosine <=> ADP + Protein tyrosine phosphate R02585 protein-tyrosine-phosphate phosphohydrolase; Protein tyrosine phosphate + H2O <=> Protein tyrosine + Orthophosphate R02586 3'-phosphoadenylylsulfate:protein-tyrosine O-sulfotransferase; 3'-Phosphoadenylyl sulfate + Protein tyrosine <=> Adenosine 3',5'-bisphosphate + Protein tyrosine-O-sulfate R02587 2-deoxy-D-glucose 6-phosphate phosphohydrolase; 2-Deoxy-D-glucose 6-phosphate + H2O <=> 2-Deoxy-D-glucose + Orthophosphate R02588 2-deoxy-alpha-D-glucoside deoxyglucohydrolase; 2-Deoxy-alpha-D-glucoside + H2O <=> Alcohol + 2-Deoxy-D-glucose R02589 3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating); 3-Hydroxybenzoate + Oxygen + NADH + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O R02590 CTP:choline-phosphate cytidylyltransferase; CTP + N-Trimethyl-2-aminoethylphosphonate <=> Diphosphate + CMP-N-trimethyl-2-aminoethylphosphonate R02591 sn-glycero-3-phosphocholine cholinephosphohydrolase; sn-Glycero-3-phosphocholine + H2O <=> Glycerol + Choline phosphate R02592 N-Dimethyl-2-aminoethylphosphonate + Activated methyl group <=> N-Trimethyl-2-aminoethylphosphonate R02593 coniferyl alcohol:NADP+ oxidoreductase; Coniferyl alcohol + NADP+ <=> Coniferyl aldehyde + NADPH + H+ R02594 UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase; UDP-glucose + Coniferyl alcohol <=> UDP + Coniferin R02595 coniferin beta-D-glucosidase; Coniferin + H2O <=> Coniferyl alcohol + D-Glucose R02596 donor:hydrogen-peroxide oxidoreductase; Coniferyl alcohol <=> Guaiacyl lignin R02597 N-acylneuraminate-9-phosphate phosphohydrolase; N-Acylneuraminate 9-phosphate + H2O <=> N-Acylneuraminate + Orthophosphate R02598 CMP-N-acylneuraminate N-acylneuraminohydrolase; CMP-N-acylneuraminate + H2O <=> CMP + N-Acylneuraminate R02599 CTP:N-acylneuraminate cytidylyltransferase; CTP + N-Acylneuraminate <=> Diphosphate + CMP-N-acylneuraminate R02600 isethionate:NADP+ oxidoreductase; Sulfoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethanesulfonate + NADP+ R02601 4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming); 2-Hydroxy-2,4-pentadienoate + H2O <=> 4-Hydroxy-2-oxopentanoate R02602 4-oxalocrotonate carboxy-lyase; gamma-Oxalocrotonate <=> 2-Hydroxy-2,4-pentadienoate + CO2 R02603 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate succinylhydrolase; 2-Hydroxy-2,4-pentadienoate + Succinate <=> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O R02604 2-hydroxymuconate-semialdehyde formylhydrolase; 2-Hydroxy-2,4-pentadienoate + Formate <=> 2-Hydroxymuconate semialdehyde + H2O R02605 L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating); 2-Amino-4-chloro-4-pentenoic acid + H2O <=> 2-Hydroxy-2,4-pentadienoate + Cl- + Ammonia R02606 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase; 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O <=> Benzoate + 2-Hydroxy-2,4-pentadienoate R02609 5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase; 5beta-Cholestan-3-one + NADP+ <=> Cholest-4-en-3-one + NADPH + H+ R02610 5alpha-cholestan-3-one:NADP+ delta4-oxidoreductase; 5alpha-Cholestan-3-one + NADP+ <=> Cholest-4-en-3-one + NADPH + H+ R02611 phenylethylalcohol:NAD+ oxidoreductase; Phenylethyl alcohol + NAD+ <=> Phenylacetaldehyde + NADH + H+ R02612 phenethylamine:(acceptor) oxidoreductase (deaminating); Phenethylamine + H2O + Acceptor <=> Phenylacetaldehyde + Ammonia + Reduced acceptor R02613 phenethylamine:oxygen oxidoreductase (deaminating); Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide R02615 styrene-oxide isomerase; Styrene oxide <=> Phenylacetaldehyde R02616 acyl-CoA:beta-D-galactoside 6-acetyltransferase; Acetyl-CoA + beta-D-Galactoside <=> CoA + 6-Acetyl-beta-D-galactoside R02617 2,3-dehydroacyl-CoA:sn-glycerol-3-phosphate O-acyltransferase; 2,3-Dehydroacyl-CoA + sn-Glycerol 3-phosphate <=> CoA + 1-Acyl-sn-glycerol 3-phosphate R02618 3-Sulfino-L-alanine + NAD+ + H2O <=> 3-Sulfinylpyruvate + Ammonia + NADH + H+ R02619 3-sulfino-L-alanine:2-oxoglutarate aminotransferase; 3-Sulfino-L-alanine + 2-Oxoglutarate <=> 3-Sulfinylpyruvate + L-Glutamate R02620 long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); Long-chain aldehyde + CoA + NADP+ <=> Long-chain acyl-CoA + NADPH + H+ R02621 protein arginine iminohydrolase; Protein-L-arginine + H2O <=> Protein L-citrulline + Ammonia R02622 protein glutamine amidohydrolase; Protein glutamine + H2O <=> Protein glutamate + Ammonia R02623 S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase; S-Adenosyl-L-methionine + Protein glutamate <=> S-Adenosyl-L-homocysteine + Protein glutamate methyl ester R02624 protein-L-glutamate-O4-methyl-ester acylhydrolase; Protein glutamate methyl ester + H2O <=> Protein glutamate + Methanol R02625 ATP:protein-L-histidine N(pi)-phosphotransferase; ATP + Protein histidine <=> ADP + Protein N(pi)-phospho-L-histidine R02626 ATP:protein-L-histidine N(tau)-phosphotransferase; ATP + Protein histidine <=> ADP + Protein N(tau)-phospho-L-histidine R02627 S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase; S-Adenosyl-L-methionine + Protein histidine <=> S-Adenosyl-L-homocysteine + Protein N(tau)-methyl-L-histidine R02628 phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase; Phosphoenolpyruvate + Protein histidine <=> Pyruvate + Protein N(pi)-phospho-L-histidine R02630 protein-N(pi)-phosphohistidine:D-mannose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Mannose <=> Protein histidine + D-Mannose 6-phosphate R02631 protein-N(pi)-phosphohistidine:D-glucosamine 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Glucosamine <=> Protein histidine + D-Glucosamine 6-phosphate R02632 3'-phosphoadenylylsulfate:quercetin-3-sulfate 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3'-bissulfate R02633 3'-phosphoadenylylsulfate:quercetin-3-sulfate 4'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,4'-bissulfate R02634 UTP:1-phospho-alpha-D-galacturonate uridylyltransferase; UDP-D-galacturonate pyrophospholylase; UDP-D-galacturonate + Diphosphate <=> 1-Phospho-alpha-D-galacturonate + UTP R02636 UDP-D-galacturonate carboxy-lyase; UDP-D-galacturonate <=> UDP-L-arabinose + CO2 R02637 3-dehydro-L-gulonate:NAD+ 2-oxidoreductase; 3-Dehydro-L-gulonate + NAD+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADH + H+ R02639 3-dehydro-L-gulonate:NADP+ 2-oxidoreductase; 3-Dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADPH + H+ R02640 L-gulonate:NAD+ 3-oxidoreductase; L-Gulonate + NAD+ <=> 3-Dehydro-L-gulonate + NADH + H+ R02642 3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase; 3-Oxo-5beta-steroid + Acceptor <=> 3-Oxo-Delta4-steroid + Reduced acceptor R02643 3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase; 3-Oxo-5alpha-steroid + Acceptor <=> 3-Oxo-Delta4-steroid + Reduced acceptor R02644 3-oxo-delta5-steroid delta5-delat4-isomerase; 3-Oxo-Delta5-steroid <=> 3-Oxo-Delta4-steroid R02646 urate-3-ribonucleoside:phosphate D-ribosyltransferase; Urate-3-ribonucleoside + Orthophosphate <=> Urate + alpha-D-Ribose 1-phosphate R02648 glycerol 1,2-cyclic phosphate 2-glycerophosphohydrolase; Glycerol 1,2-cyclic phosphate + H2O <=> DL-Glycerol 1-phosphate R02649 ATP:N-acetyl-L-glutamate 5-phosphotransferase; ATP + N-Acetyl-L-glutamate <=> ADP + N-Acetyl-L-glutamate 5-phosphate R02650 ATP:N-acyl-D-mannosamine 6-phosphotransferase; ATP + N-Acyl-D-mannosamine <=> ADP + N-Acyl-D-mannosamine 6-phosphate R02651 N-acyl-D-mannosamine:NAD+ 1-oxidoreductase; N-Acyl-D-mannosamine + NAD+ <=> N-Acyl-D-mannosaminolactone + NADH + H+ R02652 N-acyl-D-glucosamine 2-epimerase; N-Acyl-D-glucosamine <=> N-Acyl-D-mannosamine R02654 UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + N-Acetyl-D-glucosaminylphosphatidylinositol R02655 gentisate aldehyde:NAD+ oxidoreductase; Gentisate aldehyde + NAD+ + H2O <=> 2,5-Dihydroxybenzoate + NADH + H+ R02656 gentisate:oxygen 1,2-oxidoreductase (decyclizing); 2,5-Dihydroxybenzoate + Oxygen <=> Maleylpyruvate R02657 2,5-Dihydroxybenzoate + Hydrogen peroxide <=> Gentisate aldehyde + Oxygen + H2O R02658 ATP:2-dehydro-D-gluconate 6-phosphate; ATP + 2-Keto-D-gluconic acid <=> ADP + 6-Phospho-2-dehydro-D-gluconate R02659 2-Keto-D-gluconic acid <=> 2-Dehydro-D-glucono-1,5-lactone + H2O R02661 2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase; 2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor R02662 2-methylpropanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase; 2-Methylpropanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine R02663 2-Methylpropanoyl-CoA <=> Branched chain fatty acid R02664 2-Phospho-D-glycerate + ATP <=> 2,3-Bisphospho-D-glycerate + ADP R02665 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing); 3-Hydroxyanthranilate + Oxygen <=> 2-Amino-3-carboxymuconate semialdehyde R02666 3-hydroxyanthranilate:oxygen oxidoreductase; 3-Hydroxyanthranilate + Oxygen <=> 6-Imino-5-oxocyclohexa-1,3-dienecarboxylate + Hydrogen peroxide R02667 S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase; S-Adenosyl-L-methionine + 3-Hydroxyanthranilate <=> S-Adenosyl-L-homocysteine + 3-Hydroxy-4-methylanthranilate R02668 3-hydroxy-L-kynurenine hydrolase; 3-Hydroxy-L-kynurenine + H2O <=> 3-Hydroxyanthranilate + L-Alanine R02669 3-Hydroxyanthranilate <=> 2-Aminophenol + CO2 R02670 2 3-Hydroxyanthranilate + 4 Oxygen <=> Cinnavalininate + 2 Superoxide + 2 Hydrogen peroxide + 2 H+ R02671 3-Hydroxyanthranilate + S-Adenosyl-L-methionine <=> 3-Methoxyanthranilate + S-Adenosyl-L-homocysteine R02672 4-hydroxybenzoylformate carboxy-lyase; 4-Hydroxyphenylglyoxylate <=> 4-Hydroxybenzaldehyde + CO2 R02673 (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase; (S)-4-Hydroxymandelate + Oxygen <=> 4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2 R02675 4-methylphenol:oxidized azurin oxidoreductase (methyl-hydroxylating); 4-Cresol + 4 Oxidized azurin + H2O <=> 4-Hydroxybenzaldehyde + 4 Reduced azurin + 4 H+ R02676 4-hydroxymandelonitrile hydroxybenzaldehyde-lyase; (S)-4-Hydroxymandelonitrile <=> Hydrogen cyanide + 4-Hydroxybenzaldehyde R02677 ADPmannose sugarphosphohydrolase; ADP-mannose + H2O <=> AMP + D-Mannose 1-phosphate R02678 indole-3-acetaldehyde:NAD+ oxidoreductase; Indole-3-acetaldehyde + NAD+ + H2O <=> Indole-3-acetate + NADH + H+ R02679 indole-3-ethanol:NAD+ oxidoreductase; Indole-3-ethanol + NAD+ <=> Indole-3-acetaldehyde + NADH + H+ R02680 indole-3-ethanol:NADP+ oxidoreductase; Indole-3-ethanol + NADP+ <=> Indole-3-acetaldehyde + NADPH + H+ R02681 indole-3-acetaldehyde:oxygen oxidoreductase; Indole-3-acetaldehyde + Oxygen + H2O <=> Indole-3-acetate + Hydrogen peroxide R02682 long-chain-acyl-ethyl-ester acylhydrolase; Long-chain-fatty-acyl ethyl ester + H2O <=> Long-chain fatty acid + Ethanol R02683 (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NAD+ 15-oxidoreductase; Prostaglandin F2alpha + NAD+ <=> 15-Keto-prostaglandin F2alpha + NADH + H+ R02684 (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase; Prostaglandin F2alpha + NADP+ <=> Prostaglandin D2 + NADPH + H+ R02685 (3S)-3-hydroxyacyl-CoA hydro-lyase; (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O R02687 1,2-diacyl-sn-glycerol acylhydrolase; 1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid R02688 1,2-diacyl-sn-glycerol acylhydrolase; 1,2-Diacyl-sn-glycerol + H2O <=> 2-Acylglycerol + Fatty acid R02689 UDP-alpha-D-glucose:1,2-diacyl-sn-glycerol 3-beta-D-glucosyltransferase; UDP-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + 3-D-Glucosyl-1,2-diacylglycerol R02691 UDP-alpha-D-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase; UDP-alpha-D-galactose + 1,2-Diacyl-sn-glycerol <=> UDP + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol R02692 1,2-diacyl-sn-glycerol:sterol O-acyltransferase; 1,2-Diacyl-sn-glycerol + Cholesterol <=> 1-Acylglycerol + Cholesterol ester R02693 1,2-diacyl-sn-glycerol:sterol O-acyltransferase; 1,2-Diacyl-sn-glycerol + Sterol <=> 1-Acylglycerol + Steryl ester R02694 2,3-dehydroacyl-CoA:1,2-diacylglycerol O-acyltransferase; 2,3-Dehydroacyl-CoA + 1,2-Diacyl-sn-glycerol <=> CoA + Triacylglycerol R02695 4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase; 4-Hydroxyphenylacetaldehyde + NAD+ + H2O <=> 4-Hydroxyphenylacetate + NADH + H+ R02697 4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase; 4-Hydroxyphenylacetaldehyde + NADP+ + H2O <=> 4-Hydroxyphenylacetate + NADPH + H+ R02698 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating); 4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O R02699 4-hydroxyphenylacetate:CoA ligase (AMP-forming); ATP + 4-Hydroxyphenylacetate + CoA <=> AMP + Diphosphate + 4-Hydroxyphenylacetyl-CoA R02700 5-hydroxy-L-tryptophan:2-oxoglutarate aminotransferase; 5-Hydroxy-L-tryptophan + 2-Oxoglutarate <=> 5-Hydroxyindolepyruvate + L-Glutamate R02701 5-hydroxy-L-tryptophan decarboxy-lyase; 5-Hydroxy-L-tryptophan <=> Serotonin + CO2 R02702 5-hydroxy-L-tryptophan:oxygen 2,3-dioxygenase (indole-decyclizing); 5-Hydroxy-L-tryptophan + Oxygen <=> 5-Hydroxy-N-formylkynurenine R02703 D-mannitol-1-phosphate:NAD+ 5-oxidoreductase; D-Mannitol 1-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+ R02704 protein-N(pi)-phosphohistidine:mannitol 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + Mannitol <=> Protein histidine + D-Mannitol 1-phosphate R02705 ATP:N-acyl-D-mannosamine 6-phosphotransferase; ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate R02706 N-Acetyl-D-mannosamine + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + H2O R02707 N-acetyl-D-mannosamine N-acetylmannosaminohydrolase; N-Acetyl-D-mannosamine + UDP <=> UDP-N-acetyl-D-mannosamine + H2O R02708 4-hydroxyphenylacetonitrile,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase; 4-Hydroxyphenylacetonitrile + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (S)-4-Hydroxymandelonitrile + [Oxidized NADPH---hemoprotein reductase] + H2O R02709 UDPglucose:4-hydroxymandelonitrile glucosyltransferase; UDP-glucose + 4-Hydroxymandelonitrile <=> UDP + Taxiphyllin R02711 4-methylene-L-glutamate:ammonia ligase (AMP-forming); ATP + 4-Methylene-L-glutamate + Ammonia <=> AMP + Diphosphate + 4-Methylene-L-glutamine R02712 4-methylene-L-glutamine amidohydrolase; 4-Methylene-L-glutamine + H2O <=> 4-Methylene-L-glutamate + Ammonia R02713 4-Methylene-L-glutamate <=> 4-Methylene-2-oxoglutarate R02714 D-arabinono-1,4-lactone lactonohydrolase; D-Arabinono-1,4-lactone + H2O <=> D-Arabinonate R02715 D-arabinono-1,4-lactone:oxygen oxidoreductase; D-Arabinono-1,4-lactone + Oxygen <=> Dehydro-D-arabinono-1,4-lactone + Hydrogen peroxide R02716 UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase; UDP-glucose + Poly(ribitol phosphate) <=> UDP + beta-D-Glucosylpoly(ribitol phosphate) R02717 UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Poly(ribitol phosphate) <=> UDP + N-Acetyl-D-glucosaminyl-poly(ribitol phosphate) R02718 D-alanine:poly(ribitol phosphate) ligase (AMP-forming); ATP + D-Alanine + Poly(ribitol phosphate) <=> AMP + Diphosphate + O-D-Alanyl-poly(ribitol phosphate) R02719 xanthosine 5'-phosphate phosphohydrolase; Xanthosine 5'-phosphate + H2O <=> Xanthosine + Orthophosphate R02720 XTP pyrophosphohydrolase; XTP diphosphohydrolase (diphosphate-forming); XTP + H2O <=> Xanthosine 5'-phosphate + Diphosphate R02721 D-Glyceraldehyde 3-phosphate + Pyruvate <=> 5-(2-Hydroxyethyl)-4-methylthiazole R02722 L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]; L-Serine + Indoleglycerol phosphate <=> L-Tryptophan + D-Glyceraldehyde 3-phosphate + H2O R02723 Cholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 22(R)-Hydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin R02724 cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving); Cholesterol + 3 Oxygen + 6 H+ + 6 Reduced adrenal ferredoxin <=> 4-Methylpentanal + Pregnenolone + 4 H2O + 6 Oxidized adrenal ferredoxin R02725 androstenedione,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11-hydroxylating); 2 Reduced adrenal ferredoxin + Androstenedione + Oxygen + 2 H+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + 2 Oxidized adrenal ferredoxin + H2O R02726 steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11-hydroxylating); 2 Reduced adrenal ferredoxin + Steroid + Oxygen + 2 H+ <=> 11beta-Hydroxysteroid + 2 Oxidized adrenal ferredoxin + H2O R02727 alpha,alpha-trehalose:orthophosphate beta-D-glucosyltransferase; alpha,alpha-Trehalose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R02728 beta-D-glucose 1-phosphate 1,6-phosphomutase; beta-D-Glucose 1-phosphate <=> beta-D-Glucose 6-phosphate R02729 5-formiminotetrahydrofolate:glycine N-formiminotransferase; 5-Formiminotetrahydrofolate + Glycine <=> Tetrahydrofolate + N-Formiminoglycine R02730 D-fructose-2,6-bisphosphate 6-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 2-phosphate + Orthophosphate R02731 D-fructose-2,6-bisphosphate 2-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate R02732 ATP:D-fructose-6-phosphate 2-phosphotransferase; ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 2,6-bisphosphate R02733 N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase; N6-Acetyl-LL-2,6-diaminoheptanedioate + H2O <=> Acetate + LL-2,6-Diaminoheptanedioate R02734 N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; N-Succinyl-LL-2,6-diaminoheptanedioate + H2O <=> Succinate + LL-2,6-Diaminoheptanedioate R02735 LL-2,6-diaminoheptanedioate 2-epimerase; LL-2,6-Diaminoheptanedioate <=> meso-2,6-Diaminoheptanedioate R02736 beta-D-glucose-6-phosphate:NADP+ 1-oxoreductase; beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+ R02737 UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; UDP-glucose + alpha-D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate R02738 protein-N(pi)-phosphohistidine:D-glucose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Glucose <=> Protein histidine + alpha-D-Glucose 6-phosphate R02739 alpha-D-glucose 6-phosphate ketol-isomerase; alpha-D-Glucose 6-phosphate <=> beta-D-Glucose 6-phosphate R02740 alpha-D-glucose 6-phosphate ketol-isomerase; alpha-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate R02741 gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming); ATP + gamma-L-Glutamyl-L-cysteine + beta-Alanine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteinyl-beta-alanine R02742 gamma-glutamylcysteine:NADP+ oxidoreductase; 2 gamma-L-Glutamyl-L-cysteine + NADP+ <=> Bis-gamma-glutamylcystine + NADPH + H+ R02743 gamma-L-glutamyl-L-cysteine gamma-glutamyl cyclotransferase (5-oxoproline-forming); gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine R02744 sn-Glycero-3-phosphocholine + Carboxylate <=> 2-Acyl-sn-glycero-3-phosphocholine + H2O R02745 1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase; 1-(1-Alkenyl)-sn-glycero-3-phosphocholine + H2O <=> Aldehyde + sn-Glycero-3-phosphocholine R02746 1-acyl-sn-glycero-3-phosphocholine acylhydrolase; 1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid R02747 2-acyl-sn-glycero-3-phosphocholine acylhydrolase; 2-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid R02748 deoxyinosine:orthophosphate ribosyltransferase; Deoxyinosine + Orthophosphate <=> Hypoxanthine + 2-Deoxy-D-ribose 1-phosphate R02749 2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase; 2-Deoxy-D-ribose 1-phosphate <=> 2-Deoxy-D-ribose 5-phosphate R02750 ATP:2-deoxy-D-ribose 5-phosphotransferase; 2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP R02751 deoxyribonucleotide 3'-phosphohydrolase; Deoxynucleoside 3'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate R02752 D-glucarate hydro-lyase; D-Glucarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O R02754 5-dehydro-4-deoxy-D-glucarate tartronate-semialdehyde-lyase; 5-Dehydro-4-deoxy-D-glucarate <=> Pyruvate + 2-Hydroxy-3-oxopropanoate R02755 meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating); meso-2,6-Diaminoheptanedioate + NADP+ + H2O <=> L-2-Amino-6-oxoheptanedioate + Ammonia + NADPH + H+ R02756 1-Acyl-sn-glycerol 3-phosphate + NADP+ <=> Acylglycerone phosphate + NADPH + H+ R02757 ATP:acylglycerol 3-phosphotransferase; ATP + 1-Acylglycerol <=> ADP + 1-Acyl-sn-glycerol 3-phosphate R02758 ATP:acylglycerol 3-phosphotransferase; ATP + 2-Acylglycerol <=> ADP + 2-Acyl-sn-glycerol 3-phosphate R02760 2,3-dehydroacyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase; 2,3-Dehydroacyl-CoA + 1-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate R02762 2-hydroxymuconate semialdehyde:NAD+ 6-oxidoreductase; 2-Hydroxymuconate semialdehyde + NAD+ + H2O <=> 2-Hydroxymuconate + NADH + H+ R02763 2-Hydroxymuconate semialdehyde + CO2 <=> 3-Carboxy-2-hydroxymuconate semialdehyde R02764 (S)-methylmalonyl-CoA hydrolase; (S)-Methylmalonyl-CoA + H2O <=> Methylmalonate + CoA R02765 methylmalonyl-CoA epimerase; (R)-Methylmalonyl-CoA <=> (S)-Methylmalonyl-CoA R02766 (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase; (3R)-3-Hydroxyacyl-[acyl-carrier protein] + NAD+ <=> 3-Oxoacyl-[acyl-carrier protein] + NADH + H+ R02767 (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxyacyl-[acyl-carrier protein] + NADP+ <=> 3-Oxoacyl-[acyl-carrier protein] + NADPH + H+ R02768 acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxoacyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein R02769 phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-acylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating); N-Acylneuraminate 9-phosphate + Orthophosphate <=> N-Acyl-D-mannosamine 6-phosphate + Phosphoenolpyruvate + H2O R02770 N-acyl-D-glucosamine 6-phosphate 2-epimerase; N-Acyl-D-mannosamine 6-phosphate <=> N-Acyl-D-glucosamine 6-phosphate R02772 dTDP-4-acetamido-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase; dTDP-4-acetamido-4,6-dideoxy-D-glucose + 2-Oxoglutarate + CoA <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate + Acetyl-CoA R02773 dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase; dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate R02776 dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase; dTDP-6-deoxy-beta-L-talose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ R02777 dTDP-beta-L-rhamnose:NADP+ 4-oxidoreductase; dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase; dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ R02778 trehalose-6-phosphate phosphohydrolase; alpha,alpha'-Trehalose 6-phosphate + H2O <=> alpha,alpha-Trehalose + Orthophosphate R02780 alpha,alpha-Trehalose + Protein N(pi)-phospho-L-histidine <=> alpha,alpha'-Trehalose 6-phosphate + Protein histidine R02781 L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase; L-Glutamine + 2,4,6/3,5-Pentahydroxycyclohexanone <=> 2-Oxoglutaramate + 1-Amino-1-deoxy-scyllo-inositol R02782 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase; 2,4,6/3,5-Pentahydroxycyclohexanone <=> 3D-3,5/4-Trihydroxycyclohexane-1,2-dione + H2O R02783 UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanine + D-Glutamate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate R02786 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine R02788 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminoheptanedioate ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-Diaminoheptanedioate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate R02789 UDP-N-acetyl-alpha-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R beta-1,3-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R R02790 UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R R02791 UDP-alpha-D-galactose:beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R 3-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> UDP + alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R R02792 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate:NAD+ 7-oxidoreductase; Cholic acid + NAD+ <=> 7-Oxodeoxycholate + NADH + H+ R02793 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate:NADP+ 12-oxidoreductase; Cholic acid + NADP+ <=> 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate + NADPH + H+ R02794 cholate:CoA ligase (AMP-forming); ATP + Cholic acid + CoA <=> AMP + Diphosphate + Choloyl-CoA R02797 taurocholate amidohydrolase; Taurocholate + H2O <=> Cholic acid + Taurine R02798 Cholic acid <=> 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + H2O R02799 11-epi-prostaglandin F2alpha:NADP+ 11-oxidoreductase; 11-epi-Prostaglandin F2alpha + NADP+ <=> Prostaglandin D2 + H+ + NADPH R02800 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase; Prostaglandin D2 + NADP+ <=> (5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+ R02801 Prostaglandin D2 <=> Prostaglandin J2 + H2O R02802 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); Nitrogen + 2 e- + 2 H+ <=> Diimine R02804 nitrogen:ferricytochrome-c oxidoreductase (N2O-forming); Nitrogen + 2 Ferricytochrome c + H2O <=> Nitrous oxide + 2 Ferrocytochrome c + 2 H+ R02805 P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase; P1,P4-Bis(5'-xanthosyl) tetraphosphate + H2O <=> XTP + Xanthosine 5'-phosphate R02806 nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase; Thymidine + Base <=> Deoxynucleoside + Thymine R02807 Hg:NADP+ oxidoreductase; Hg + NADP+ + H+ <=> Mercury(2+) + NADPH R02808 S-adenosyl-L-methionine:amine N-methyltransferase; S-Adenosyl-L-methionine + Amine <=> S-Adenosyl-L-homocysteine + Methylated amine R02809 3'-phosphoadenylylsulfate:amine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + Amine <=> Adenosine 3',5'-bisphosphate + Sulfamate R02810 iodide:hydrogen-peroxide oxidoreductase; 2 Iodide + Hydrogen peroxide + 2 H+ <=> Iodine + 2 H2O R02811 cyanohydrin ketone-lyase; Cyanohydrin <=> Ketone + Cyanide ion R02813 (R)-10-hydroxystearate 10-hydro-lyase; (R)-10-Hydroxystearate <=> (9Z)-Octadecenoic acid + H2O R02814 oleoyl-[acyl-carrier-protein] hydrolase; Oleoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + (9Z)-Octadecenoic acid R02815 2-amino-4-hydroxypteridine aminohydrolase; Pterin + H2O <=> 2,4-Dihydroxypteridine + Ammonia R02816 2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating); Pterin + Oxygen <=> Isoxanthopterin R02817 serine-phosphoethanolamine ethanolaminephosphohydrolase; L-Serine-phosphoethanolamine + H2O <=> L-Serine + Ethanolamine phosphate R02818 Serine <=> Cysteine R02819 alditol:NAD+ 1-oxidoreductase; Alditol + NAD+ <=> Aldose + NADH + H+ R02820 alditol:NADP+ 1-oxidoreductase; Alditol + NADP+ <=> Aldose + NADPH + H+ R02821 trimethylaminoacetate:L-homosysteine S-methyltransferase; Betaine + L-Homocysteine <=> N,N-Dimethylglycine + L-Methionine R02822 epoxide hydrolase; Epoxide + H2O <=> Glycol R02823 alkene,NADH:oxygen oxidoreductase (hydroxylating); Alkene + Oxygen + NADH + H+ <=> Epoxide + NAD+ + H2O R02824 glutathione:insulin oxidoreductase; Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide R02825 5-Aminopentanoate <=> D-Proline R02826 aliphatic amide hydro-lyase; Aliphatic amide <=> Nitrile + H2O R02827 acetaldehyde oxime hydro-lyase; Aldoxime <=> Nitrile + H2O R02828 monocarboxylic acid amide hydro-lyase; Monocarboxylic acid amide <=> Nitrile + H2O R02830 orcinol,NADH:oxygen oxidoreductase (2-hydroxylating); Orcinol + Oxygen + NADH + H+ <=> 2,3,5-Trihydroxytoluene + NAD+ + H2O R02831 orsellinate carboxy-lyase; Orsellinate <=> Orcinol + CO2 R02832 pseudotropine:NADP+ 3-oxidoreductase; Tropine + NADP+ <=> Tropinone + NADPH + H+ R02833 chitosan N-acetylglucosaminohydrolase; Chitosan + H2O <=> D-Glucosaminide + Chitosan R02834 cortisol:NAD+ 11-oxidoreductase; Cortisol + NAD+ <=> Cortisone + NADH + H+ R02836 cortisol:NADP+ 11-oxidoreductase; Cortisol + NADP+ <=> Cortisone + NADPH + H+ R02837 acetyl-CoA:cortisol O-acetyltransferase; Acetyl-CoA + Cortisol <=> CoA + Cortisol 21-acetate R02838 21-deoxycortisol,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); 21-Deoxycortisol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cortisol + [Oxidized NADPH---hemoprotein reductase] + H2O R02839 3'-phosphoadenylylsulfate:cortisol 21-sulfotransferase; 3'-Phosphoadenylyl sulfate + Cortisol <=> Adenosine 3',5'-bisphosphate + Cortisol 21-sulfate R02840 cortisol delta5-delat4-isomerase; 11beta,17alpha,21-trihydroxypregnenolone:NAD+ 3-oxidoreductase; Cortisol + H+ + NADH <=> 11beta,17alpha,21-Trihydroxypregnenolone + NAD+ R02841 11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione:NADP+ delta4-oxidoreductase; 3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase; Dihydrocortisol + NADP+ <=> Cortisol + NADPH + H+ R02843 steroid,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating); 11-Deoxycortisol + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Cortisol + 2 Oxidized ferredoxin + H2O R02846 cysteine hydrogen-sulfide-lyase (adding HCN); Cysteine + Cyanide ion <=> Hydrogen sulfide + 3-Cyano-L-alanine R02847 D-aldose:NAD+ 1-oxidoreductase; D-Aldose + NAD+ <=> D-Aldonolactone + NADH + H+ R02848 ATP:D-hexose 6-phosphotransferase; ATP + D-Hexose <=> ADP + D-Hexose 6-phosphate R02849 ITP:D-hexose 6-phosphotransferase; ITP + D-Hexose <=> IDP + D-Hexose 6-phosphate R02850 dATP:D-hexose 6-phosphotransferase; dATP + D-Hexose <=> dADP + D-Hexose 6-phosphate R02851 D-lysine:2-oxocarboxylate aminotransferase; D-Lysine + 2-Oxo acid <=> 6-Amino-2-oxohexanoate + D-Amino acid R02852 D-2,6-diaminohexanoic acid 5,6-aminomutase; D-Lysine <=> (2R,5S)-2,5-Diaminohexanoate R02853 D-O-phosphoserine phosphohydrolase; O-Phospho-D-serine + H2O <=> D-Serine + Orthophosphate R02854 D-Serine + Amino acid(Arg-) <=> D-Lombricine + Ornithine R02855 (R)-acetoin:NAD+ oxidoreductase; (R)-Acetoin + NAD+ <=> Diacetyl + NADH + H+ R02856 (R)-Acetoin + NADP+ <=> Diacetyl + NADPH + H+ R02857 Hydrofluoric acid + Glycolate <=> Fluoroacetate + H2O R02858 S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase; S-Adenosyl-L-methionine + Macrocin <=> S-Adenosyl-L-homocysteine + Tylosin R02859 S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase; S-Adenosyl-L-methionine + Demethylmacrocin <=> S-Adenosyl-L-homocysteine + Macrocin R02860 nicotine:acceptor 6-oxidoreductase (hydroxylating); Nicotine + Acceptor + H2O <=> (S)-6-Hydroxynicotine + Reduced acceptor R02861 Nicotine + CO2 + H+ <=> 1-Methylpyrrolinium + Nicotinate R02862 S-adenosyl-L-methionine:pyridine N-methyltransferase; S-Adenosyl-L-methionine + Pyridine <=> S-Adenosyl-L-homocysteine + N-Methylpyridinium R02863 thiamin:beta 2-methyl-4-aminopyrimidine-5-methenyltransferase; Thiamine + Pyridine <=> Heteropyrithiamine + 5-(2-Hydroxyethyl)-4-methylthiazole R02864 S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase; Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin R02865 ATP:D-hexose 6-phosphotransferase; ATP + D-Sorbitol <=> ADP + Sorbitol 6-phosphate R02866 sorbitol-6-phosphate phosphohydrolase; Sorbitol 6-phosphate + H2O <=> D-Sorbitol + Orthophosphate R02867 ITP:D-hexose 6-phosphotransferase; ITP + D-Sorbitol <=> IDP + Sorbitol 6-phosphate R02868 dATP:D-hexose 6-phosphotransferase; dATP + D-Sorbitol <=> dADP + Sorbitol 6-phosphate R02869 S-adenosylmethioninamine:spermidine 3-aminopropyltransferase; S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Spermine R02872 presqualene-diphosphate diphosphate-lyase (reducing, squalene-forming); Presqualene diphosphate + NADPH + H+ <=> Diphosphate + Squalene + NADP+ R02874 squalene,NADPH-hemoprotein:oxygen oxidoreductase (2,3-epoxidizing); Squalene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (S)-2,3-Epoxysqualene + [Oxidized NADPH---hemoprotein reductase] + H2O R02875 squalene hydro-lyase (tetrahymanol forming); Squalene + H2O <=> Tetrahymanol R02876 Squalene <=> Hopanoid R02877 vanillyl alcohol:oxygen oxidoreductase; Vanillyl alcohol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Hydrogen peroxide R02878 1-octanol:NAD+ oxidoreductase; 1-Octanol + NAD+ <=> Octanal + NADH + H+ R02879 octane,reduced-rubredoxin:oxygen 1-oxidoreductase; Octane + 2 Reduced rubredoxin + Oxygen + 2 H+ <=> 1-Octanol + 2 Oxidized rubredoxin + H2O R02880 (S)-tetrahydroberberine:oxigen oxidoreductase; (S)-Canadine + 2 Oxygen + H+ <=> Berberine + 2 Hydrogen peroxide R02882 S-adenosyl-L-methionine:bergaptol O-methyltransferase; S-Adenosyl-L-methionine + Bergaptol <=> S-Adenosyl-L-homocysteine + Bergapten R02884 ATP:caldesmon phosphotransferase (Ca2+/calmodulin-dependent); ATP + Caldesmon <=> ADP + Caldesmon phosphate R02885 caldesmon-phosphate phosphohydrolase; Caldesmon phosphate + H2O <=> Caldesmon + Orthophosphate R02886 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase; Cellulose + H2O <=> Cellulose + Cellobiose R02887 1,4-beta-D-glucan glucohydrolase; Cellodextrin + (n-2) H2O <=> (n-2) D-Glucose + Cellobiose R02888 1,4-beta-D-oligo-D-glucan:orthophosphate alpha-D-glucosyltransferase; Cellulose + Orthophosphate <=> Cellulose + D-Glucose 1-phosphate R02889 UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; UDP-glucose + Cellulose <=> UDP + Cellulose R02890 GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; GDP + Cellulose <=> GDP-glucose + Cellulose R02892 4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase; 4,5alpha-Dihydrocortisone + NADP+ <=> Cortisone + NADPH + H+ R02893 17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione:NADP+ delta4-oxidoreductase; 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ <=> Cortisone + NADPH + H+ R02894 D-proline:oxygen oxidoreductase; D-Proline + Oxygen <=> 1-Pyrroline-2-carboxylate + Hydrogen peroxide R02895 D-Proline + L-Glutamine <=> Linatine R02896 D-iditol:NAD+ 2-oxidoreductase; D-Iditol + NAD+ <=> D-Sorbose + NADH + H+ R02897 UDPglucose:flavanone 7-O-beta-D-glucosyltransferase; UDP-glucose + Naringenin <=> UDP + Naringenin 7-O-beta-D-glucoside R02898 flavanone lyase (decyclizing); Flavanone <=> 2'-Hydroxychalcone R02899 sinapoyl-CoA:D-glucarate O-sinapoyltransferase; Sinapoyl-CoA + D-Glucarate <=> CoA + O-Sinapoylglucarate R02901 phloretin acylhydrolase (phloroglucinol-forming); Phloretin + H2O <=> Phloretate + Phloroglucinol R02902 Retinoate + UDP-glucuronate <=> all-trans-Retinoyl-beta-glucuronide + UDP R02903 ATP:rhodopsin phosphotransferase; ATP + Rhodopsin <=> ADP + Phosphorhodopsin R02904 Rhodopsin <=> 11-cis-Retinal R02905 Rhodopsin + hn <=> Bathorhodopsin R02906 scytalone:NADP+ delta5-oxidoreductase; Scytalone + NADP+ <=> 1,3,6,8-Naphthalenetetrol + NADPH + H+ R02907 scytalone 7,8-hydro-lyase; Scytalone <=> 1,3,8-Naphthalenertriol + H2O R02908 5-hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing); Serotonin + H2O + Oxygen <=> 5-Hydroxyindoleacetaldehyde + Ammonia + Hydrogen peroxide R02909 5-hydroxytryptamine:oxygen 2,3-dioxygenase (indole-decyclizing); Serotonin + Oxygen <=> Formyl-5-hydroxykynurenamine R02910 S-adenosyl-L-methionine:amine N-methyltransferase; S-Adenosyl-L-methionine + Serotonin <=> S-Adenosyl-L-homocysteine + N-Methylserotonin R02911 acetyl-CoA:aralkylamine N-acetyltransferase; Acetyl-CoA + Serotonin <=> CoA + N-Acetylserotonin R02912 serotonin O-methyltransferase; Serotonin + 5-Methyltetrahydrofolate <=> 5-Methoxytryptamine + Tetrahydrofolate R02914 4,5-dihydro-4-oxo-5-imidazolepropanoate hydro-lyase; 4-Imidazolone-5-propanoate <=> Urocanate + H2O R02915 medicarpin:NADP+ 2'-oxidoreductase; Medicarpin + NADP+ + H2O <=> (-)-Vestitone + NADPH + H+ R02917 S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase; S-Adenosyl-L-methionine + tRNA guanine <=> S-Adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine R02918 L-tyrosine:tRNA(Tyr) ligase (AMP-forming); ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr) R02919 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing); L-Adrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Methylamine + Hydrogen peroxide R02920 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + L-Adrenaline <=> S-Adenosyl-L-homocysteine + L-Metanephrine R02921 CTP:D-ribitol-5-phosphate cytidylyltransferase; CTP + D-Ribitol 5-phosphate <=> Diphosphate + CDP-ribitol R02922 creatinine iminohydrolase; Creatinine + H2O <=> N-Methylhydantoin + Ammonia R02923 D-arginine:oxygen oxidoreductase (deaminating); D-Arginine + H2O + Oxygen <=> 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide R02924 D-arginine:2-oxoglutarate aminotransferase; D-Arginine + 2-Oxo acid <=> 5-Guanidino-2-oxopentanoate + D-Amino acid R02925 D-sorbitol:(acceptor) 1-oxidoreductase; D-Sorbitol + FAD <=> FADH2 + L-Sorbose R02926 melibiitol galactohydrolase; Melibiitol + H2O <=> D-Sorbitol + D-Galactose R02927 ATP:D-tagatose 6-phosphotransferase; ATP + D-Tagatose <=> ADP + D-Tagatose 6-phosphate R02928 galactitol:NAD+ 2-oxidoreductase; Galactitol + NAD+ <=> D-Tagatose + NADH + H+ R02929 L-glutamate:ethylamine ligase (ADP-forming); ATP + L-Glutamate + Ethylamine <=> ADP + Orthophosphate + N5-Ethyl-L-glutamine R02930 N5-ethyl-L-glutamine amidohydrolase; N5-Ethyl-L-glutamine + H2O <=> L-Glutamate + Ethylamine R02931 S-adenosyl-L-methionine: genistein 4'-O-methyltransferase; S-Adenosyl-L-methionine + Genistein <=> S-Adenosyl-L-homocysteine + Biochanin A R02932 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; UDP-glucose + Genistein <=> UDP + Genistin R02933 L-gulono-1,4-lactone lactonohydrolase; L-Gulono-1,4-lactone + H2O <=> L-Gulonate R02934 nucleotide:nucleoside 5'-phosphotransferase; Nucleoside 5'-phosphate + Deoxynucleoside <=> Nucleoside + Deoxynucleoside 5'-phosphate R02935 (S)-ureidoglycolate:NAD+ oxidoreductase; (S)-Ureidoglycolate + NAD+ <=> Oxalureate + NADH + H+ R02936 (S)-ureidoglycolate:NADP+ oxidoreductase; (S)-Ureidoglycolate + NADP+ <=> Oxalureate + NADPH + H+ R02937 carbamoyl-phosphate:oxamate carbamoyltransferase; Carbamoyl phosphate + Oxamate <=> Orthophosphate + Oxalureate R02938 pentanamide amidohydrolase; Pentanamide + H2O <=> Pentanoate + Ammonia R02940 2-propyn-1-al:NAD+ oxidoreductase; 2-Propynal + NAD+ + H2O <=> Propynoate + NADH + H+ R02941 salicylaldehyde:NAD+ oxidoreductase; Salicylaldehyde + NAD+ + H2O <=> Salicylate + NADH + H+ R02942 acetylsalicylate O-acetylhydrolase; Aspirin + H2O <=> Salicylate + Acetate R02943 Tryptophan + Dimethylallyl diphosphate <=> Dimethylallyltryptophan + Diphosphate R02944 (+)-borneol:NAD+ oxidoreductase; (+)-Borneol + NAD+ <=> (+)-Camphor + NADH + H+ R02945 (-)-borneol:NAD+ oxidoreductase; (-)-Borneol + NAD+ <=> (-)-Camphor + NADH + H+ R02946 (R,R)-butane-2,3-diol:NAD+ oxidoreductase; (R,R)-Butane-2,3-diol + NAD+ <=> (R)-Acetoin + NADH + H+ R02948 (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase; (S)-2-Acetolactate <=> (R)-Acetoin + CO2 R02949 (R)-acetoin racemase; (R)-Acetoin <=> (S)-Acetoin R02950 4-coumarate:oxygen oxidoreductase; 4-Coumarate + Oxygen + Caffeate <=> Caffeate + H2O + Caffeoquinone R02951 UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase; UDP-glucose + 4-Coumarate <=> UDP + 4-O-beta-D-Glucosyl-4-hydroxycinnamate R02952 phenylacrylic acid decarboxylase; 4-Coumarate <=> 4-Hydroxystyrene + CO2 R02953 S-alkyl-L-cysteine alkylthiol-lyase (deaminating); S-Alkyl-L-cysteine + H2O <=> Alkyl thiol + Ammonia + Pyruvate R02954 dihydrobiochanin-A:NADP+ delta2-oxidoreductase; Dihydrobiochanin A + NADP+ <=> Biochanin A + NADPH + H+ R02955 acetyl-CoA:citramalate CoA-transferase; Acetyl-CoA + Citramalate <=> Acetate + (3S)-Citramalyl-CoA R02957 D-glucuronolactone:NAD+ oxidoreductase; D-Glucuronolactone + NAD+ + 2 H2O <=> D-Glucarate + NADH + H+ R02959 D-Glutamine <=> D-Glutamyl-peptide R02960 DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing); DNA 4,6-diamino-5-formamidopyrimidine <=> DNA adenine + H2O R02961 S-Adenosyl-L-methionine + DNA adenine <=> S-Adenosyl-L-homocysteine + DNA 6-methylaminopurine R02962 Dopaquinone <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole R02963 lactoyl-CoA hydro-lyase; Lactoyl-CoA <=> Propenoyl-CoA + H2O R02964 NADH:menaquinone oxidoreductase; Menaquinone + H+ + NADH <=> Menaquinol + NAD+ R02965 hydrogen:quinone oxidoreductase; Menaquinone + Hydrogen <=> Menaquinol R02968 naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating); Naphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydronaphthalene-1,2-diol + NAD+ R02969 hydroxymalonate:NAD+ oxidoreductase; Hydroxymalonate + NAD+ <=> Oxomalonate + NADH + H+ R02970 L-alanine:oxomalonate aminotransferase; Pyruvate + Aminomalonate <=> L-Alanine + Oxomalonate R02971 ATP:pantothenate 4'-phosphotransferase; ATP + Pantetheine <=> ADP + Pantetheine 4'-phosphate R02972 N-((R)-pantothenoyl)-L-cysteine carboxy-lyase; N-((R)-Pantothenoyl)-L-cysteine <=> Pantetheine + CO2 R02973 (R)-pantetheine amidohydrolase; Pantetheine + H2O <=> Pantothenate + Cysteamine R02974 sepiapterin aminohydrolase; Sepiapterin + H2O <=> Xanthopterin-B2 + Ammonia R02975 7,8-dihydrobiopterin:NADP+ oxidoreductase; 7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+ R02976 ATP:sphinganine 1-phosphotransferase; ATP + Sphinganine <=> ADP + Sphinganine 1-phosphate R02978 sphinganine:NADP+ 3-oxidoreductase; Sphinganine + NADP+ <=> 3-Dehydrosphinganine + NADPH + H+ R02979 Sphinganine + FAD <=> FADH2 + Sphingosine R02980 ATP:tropomyosin O-phosphotransferase; ATP + Tropomyosin <=> ADP + O-Phosphotropomyosin R02982 S-adenosyl-L-methionine:xanthotoxol O-methyltransferase; S-Adenosyl-L-methionine + Xanthotoxol <=> S-Adenosyl-L-homocysteine + Xanthotoxin R02983 dTDP-D-glucose dehydrogenase, plant; dTDP-glucose + 2 NADP+ + H2O <=> dTDP-D-glucuronate + 2 NADPH + 2 H+ R02984 dTDPglucose 4-epimerase; dTDP-glucose <=> dTDP-galactose R02985 amygdalin beta-glucosidase; Prunasin + D-Glucose <=> Amygdalin + H2O R02986 2-furoate:CoA ligase (AMP-forming); ATP + 2-Furoate + CoA <=> AMP + Diphosphate + 2-Furoyl-CoA R02987 2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating); 2-Furoyl-CoA + Acceptor + H2O <=> S-(5-Hydroxy-2-furoyl)-CoA + Reduced acceptor R02988 3-oxoadipate:NAD+ oxidoreductase; 3-Oxoadipate + NAD+ <=> 2-Maleylacetate + NADH + H+ R02989 3-oxoadipate:NADP+ oxidoreductase; 3-Oxoadipate + NADP+ <=> 2-Maleylacetate + NADPH + H+ R02990 succinyl-CoA:3-oxoadipate CoA-transferase; Succinyl-CoA + 3-Oxoadipate <=> Succinate + 3-Oxoadipyl-CoA R02991 4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase; 2-Oxo-2,3-dihydrofuran-5-acetate + H2O <=> 3-Oxoadipate R02992 4-pyridoxolactone lactonohydrolase; 4-Pyridoxolactone + H2O <=> 4-Pyridoxate R02993 4-Pyridoxate + Acceptor <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + Reduced acceptor R02994 6-endo-hydroxycineole:NAD+ 6-oxidoreductase; 6-endo-Hydroxycineole + NAD+ <=> 6-Oxocineole + NADH + H+ R02995 6-oxocineole,NADPH:oxygen oxidoreductase; 6-Oxocineole + Oxygen + NADPH + H+ <=> 1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + NADP+ + H2O R02996 arylsulfate:phenol sulfotransferase; Aryl sulfate + Phenol <=> Phenol + Aryl sulfate R02997 chlorogenate hydroloase; Chlorogenate + H2O <=> Caffeate + Quinate R02998 chlorogenate:D-glucarate 2-O-caffeoyltransferase; Chlorogenate + D-Glucarate <=> Quinate + 2-O-Caffeoylglucarate R02999 NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating); Cyanide ion + Cob(I)alamin + NADP+ <=> Cyanocobalamin + NADPH R03001 D-methionine:pyruvate aminotransferase; D-Methionine + Pyruvate <=> 4-Methylthio-2-oxobutanoic acid + L-Alanine R03003 S-adenosyl-L-methionine:DNA-cytosine N-methyltransferase; S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + DNA N4-methylcytosine R03004 deamino-NAD+ nucleotidohydrolase; Deamino-NAD+ + H2O <=> AMP + Nicotinate D-ribonucleotide R03005 ATP:nicotinamide-nucleotide adenylyltransferase; ATP + Nicotinate D-ribonucleotide <=> Diphosphate + Deamino-NAD+ R03006 formononetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Calycosin + [Oxidized NADPH---hemoprotein reductase] + H2O R03008 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A1 + 2-Oxoglutarate + Oxygen <=> Gibberellin A8 + Succinate + CO2 R03009 (gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating); Gibberellin A20 + 2-Oxoglutarate + Oxygen <=> Gibberellin A1 + Succinate + CO2 R03012 L-histidinol:NAD+ oxidoreductase; L-Histidinol + NAD+ <=> L-Histidinal + NADH + H+ R03013 L-histidinol-phosphate phosphohydrolase; L-Histidinol phosphate + H2O <=> L-Histidinol + Orthophosphate R03014 ATP:L-rhamnulose 1-phosphotransferase; ATP + L-Rhamnulose <=> ADP + L-Rhamnulose 1-phosphate R03015 formylmethanofuran:ferredoxin oxidoreductase; Formylmethanofuran + 2 Oxidized ferredoxin + H2O <=> Methanofuran + 2 Reduced ferredoxin + CO2 + 2 H+ R03016 monoterpenyl-diphosphate pyrophosphohydrolase; Monoterpenyl diphosphate + H2O <=> Monoterpenol + Diphosphate R03017 acetyl-CoA:monoterpenol O-acetyltransferase; Acetyl-CoA + Monoterpenol <=> CoA + Monoterpenol acetate ester R03018 ATP:pantothenate 4'-phosphotransferase; ATP + Pantothenate <=> ADP + D-4'-Phosphopantothenate R03019 S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase; S-Adenosyl-L-methionine + tRNA uridine <=> 5'-Methylthioadenosine + 3-[(3S)-3-Amino-3-carboxypropyl]-uridine in tRNA R03020 tRNA-uridine uracilmutase; tRNA uridine <=> tRNA pseudouridine R03021 (R)-2-hydroxystearate:NAD+ oxidoreductase; (R)-2-Hydroxystearate + NAD+ <=> 2-Oxooctadecanoic acid + NADH + H+ R03022 (S)-2-hydroxystearate:NAD+ oxidoreductase; (S)-2-Hydroxystearate + NAD+ <=> 2-Oxooctadecanoic acid + NADH + H+ R03023 4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating); 4-Nitrophenol + Oxygen + NADH + H+ <=> 4-Nitrocatechol + NAD+ + H2O R03024 4-nitrophenyl phosphate phosphohydrolase; 4-Nitrophenyl phosphate + H2O <=> 4-Nitrophenol + Orthophosphate R03025 hydrogen:coenzyme F420 oxidoreductase; Coenzyme F420 + Hydrogen <=> Reduced coenzyme F420 R03026 (S)-3-hydroxybutanoyl-CoA hydro-lyase; (S)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O R03027 (3R)-3-hydroxybutanoyl-CoA hydro-lyase; (R)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O R03028 glutaconyl-1-CoA carboxy-lyase; 4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming); Glutaconyl-1-CoA <=> Crotonoyl-CoA + CO2 R03030 L-3-aminobutyryl-CoA ammonia-lyase; L-3-Aminobutyryl-CoA <=> Crotonoyl-CoA + Ammonia R03031 vinylacetyl-CoA Delta3-Delta2-isomerase; Vinylacetyl-CoA <=> Crotonoyl-CoA R03032 D-arabinonate hydro-lyase; D-Arabinonate <=> 2-Dehydro-3-deoxy-D-xylonate + H2O R03033 D-galactonate hydro-lyase; D-Galactonate <=> 2-Dehydro-3-deoxy-D-galactonate + H2O R03034 D-galactono-1,4-lactone hydroxyacylhydrolase; D-Galactono-1,4-lactone + H2O <=> D-Galactonate R03035 ATP:pantetheine-4'-phosphate adenylyltransferase; ATP + Pantetheine 4'-phosphate <=> Diphosphate + Dephospho-CoA R03036 dephospho-CoA nucleotidohydrolase; Dephospho-CoA + H2O <=> Pantetheine 4'-phosphate + AMP R03037 isochorismate pyruvate-hydrolase; Isochorismate + H2O <=> (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate + Pyruvate R03038 L-alanine:tRNA(Ala) ligase (AMP-forming); ATP + L-Alanine + tRNA(Ala) <=> AMP + Diphosphate + L-Alanyl-tRNA R03039 L-alanyl-tRNA(Ala):phosphatidylglycerol alanyltransferase; L-Alanyl-tRNA + Phosphatidylglycerol <=> tRNA(Ala) + 3-O-L-Alanyl-1-O-phosphatidylglycerol R03040 3-propylmalate glyoxylate-lyase (CoA-pentanoylating); 3-Propylmalate + CoA <=> Pentanoyl-CoA + H2O + Glyoxylate R03042 polyphosphate phosphohydrolase; Polyphosphate(n) + H2O <=> Polyphosphate(n-1) + Orthophosphate R03043 21-hydroxysteroid:NAD+ 21-oxidoreductase; Pregnan-21-ol + NAD+ <=> Pregnan-21-al + NADH + H+ R03044 Pregnan-21-al + NADPH + H+ <=> Pregnan-21-ol + NADP+ R03045 3-hydroxypropionyl-CoA hydro-lyase; 3-Hydroxypropionyl-CoA <=> Propenoyl-CoA + H2O R03046 beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming); beta-Alanyl-CoA <=> Propenoyl-CoA + Ammonia R03048 11-cis-retinol:NAD+ oxidoreductase; 11-cis-Retinol + NAD+ <=> 11-cis-Retinal + NADH + H+ R03049 11-cis-retinyl-palmitate acylhydrolase; 11-cis-Retinyl palmitate + H2O <=> 11-cis-Retinol + Hexadecanoic acid R03050 2-acetolactate pyruvate-lyase (carboxylating); 2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate R03051 2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing); 2-Acetolactate + NADPH + H+ <=> 2,3-Dihydroxy-3-methylbutanoate + NADP+ R03052 2-acetolactate methylmutase; 2-Acetolactate <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid R03053 L-2-aminohexanoate:2-oxoglutarate aminotransferase; L-Norleucine + 2-Oxoglutarate <=> 2-Oxohexanoic acid + L-Glutamate R03054 cinnamyl-alcohol:NADP+ oxidoreductase; Cinnamaldehyde + NADPH + H+ <=> Cinnamyl alcohol + NADP+ R03055 (R)-5,6-dihydrothymine amidohydrolase; (R)-5,6-Dihydrothymine + H2O <=> (R)-3-Ureidoisobutyrate R03056 acetyl-CoA:gentamicin-C1a N2'-acetyltransferase; Acetyl-CoA + Gentamicin C1a <=> CoA + N2'-Acetylgentamicin C1a R03057 (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase; Leukotriene A4 + H2O <=> Leukotriene B4 R03058 arachidonate:oxygen 5-oxidoreductase; 5(S)-HPETE <=> Leukotriene A4 + H2O R03059 (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening); Leukotriene A4 + Glutathione <=> Leukotriene C4 R03060 3'-ribonucleotide phosphohydrolase; 3'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate R03062 cephalosporin-C acetylhdrolase; Cephalosporin C + H2O <=> Deacetylcephalosporin C + Acetate R03063 cephalosporin-C:2-oxoglutarate aminotransferase; Cephalosporin C + 2-Oxoglutarate <=> (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + D-Glutamate R03064 acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase; Cephalosporin C + CoA <=> Deacetylcephalosporin C + Acetyl-CoA R03065 acetyl-CoA:chloramphenicol O3-acetyltransferase; Acetyl-CoA + Chloramphenicol <=> CoA + Chloramphenicol 3-acetate R03066 6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase; 6-(Hydroxymethyl)-7,8-dihydropterin + 4-Aminobenzoate <=> Dihydropteroate + H2O R03067 (7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase; 6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate R03069 (2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming); 2,3-Dimethylmaleate + H2O <=> (2R,3S)-2,3-Dimethylmalate R03070 methylitaconate Delta2-Delta3-isomerase; Methylitaconate <=> 2,3-Dimethylmaleate R03071 ferrocytochrome:nitrate oxidoreductase; 2 Ferrocytochrome + Nitrate <=> 2 Ferricytochrome + Nitrite + H2O R03072 S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase; S-Adenosyl-L-methionine + Nocardicin E <=> 5'-Methylthioadenosine + Isonocardicin A R03073 nocardicin-A epimerase; isonocardicin-A epimerase; Isonocardicin A <=> Nocardicin A R03075 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase; D-Glucose + Sinapine <=> 1-O-Sinapoyl-beta-D-glucose + Choline R03076 protein-N(pi)-phosphohistidine:sugar phosphotransferase; Protein N(pi)-phospho-L-histidine + Sugar <=> Protein histidine + Sugar phosphate R03077 UTP:beta-L-arabinose-1-phosphate uridylyltransferase; UTP + beta-L-Arabinose 1-phosphate <=> Diphosphate + UDP-L-arabinose R03078 UDP-L-arabinofuranose + Arabinan <=> Arabinan + UDP R03079 UDP-L-arabinose <=> Pentosan + UDP R03080 (R)-propane-1,2-diol:NAD+ oxidoreductase; (R)-Propane-1,2-diol + NAD+ <=> (R)-Lactaldehyde + NADH + H+ R03081 2-dehydro-3-deoxy-D-fuconate glycolaldehyde; 2-Dehydro-3-deoxy-D-fuconate <=> Pyruvate + (R)-Lactaldehyde R03082 (R)-lactaldehyde:NAD+ oxidoreductase (glutathione-formylating); (R)-Lactaldehyde + Glutathione + NAD+ <=> (R)-S-Lactoylglutathione + NADH + H+ R03083 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (cyclyzing); 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <=> 3-Dehydroquinate + Orthophosphate R03084 3-dehydroquinate hydro-lyase; 3-Dehydroquinate <=> 3-Dehydroshikimate + H2O R03086 estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating); Estradiol-17beta + Reduced acceptor + Oxygen <=> 6beta-Hydroxy-17beta-estradiol + Acceptor + H2O R03087 19-oxotestosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (aromatizing, formate-forming); 19-Oxotestosterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Estradiol-17beta + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O R03088 Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O R03089 Estradiol-17beta + H+ + Oxygen + NADPH <=> Estriol + NADP+ + H2O R03090 Estradiol-17beta + H+ + Oxygen + NADPH <=> 2-Hydroxyestradiol + NADP+ + H2O R03091 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); Estradiol-17beta + UDP-glucuronate <=> Estradiol-17beta 3-glucuronide + UDP R03092 Indole-3-acetate + Oxygen <=> 3-Methyldioxyindole + CO2 R03093 3-indoleacetonitrile aminohydrolase; 3-Indoleacetonitrile + 2 H2O <=> Indole-3-acetate + Ammonia R03094 UDPglucose:indole-3-acetate beta-D-glucosyltransferase; UDP-glucose + Indole-3-acetate <=> UDP + Indole-3-acetyl-beta-1-D-glucoside R03095 indoleacetate:L-lysine ligase (ADP-forming); ATP + Indole-3-acetate + L-Lysine <=> ADP + Orthophosphate + N(6)-[(Indol-3-yl)acetyl]-L-lysine R03096 indole-3-acetamide amidohydrolase; (Indol-3-yl)acetamide + H2O <=> Indole-3-acetate + Ammonia R03097 Indole-3-acetate + Oxygen <=> 2-Formaminobenzoylacetate R03098 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase; ATP:L-2-aminoadipate 6-O-adenylyltransferase; L-2-Aminoadipate + ATP <=> L-2-Aminoadipate adenylate + Diphosphate R03102 L-2-aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase; L-2-Aminoadipate 6-semialdehyde + NAD+ + H2O <=> L-2-Aminoadipate + NADH + H+ R03103 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase; L-2-Aminoadipate 6-semialdehyde + NADP+ + H2O <=> L-2-Aminoadipate + NADPH + H+ R03104 3-mercaptolactate:NAD+ oxidoreductase; 3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H+ R03105 3-mercaptopyruvate:sulfide sulfurtransferase; Mercaptopyruvate + Thioredoxin <=> Hydrogen sulfide + Pyruvate + Thioredoxin disulfide R03107 plasmenylcholine 2-acylhydrolase; Plasmenylcholine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphocholine + Fatty acid R03109 acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase; Acyl-CoA + 1-(1-Alkenyl)-sn-glycero-3-phosphocholine <=> CoA + Plasmenylcholine R03110 CDPcholine:1-alkenyl-2-acylglycerol cholinephosphotransferase; CDP-choline + 1-Alkenyl-2-acylglycerol <=> CMP + Plasmenylcholine R03111 S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase; S-Adenosyl-L-methionine + Sterigmatocystin <=> S-Adenosyl-L-homocysteine + O-Methylsterigmatocystin R03112 S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase; S-Adenosyl-L-methionine + 6-Demethylsterigmatocystin <=> S-Adenosyl-L-homocysteine + Sterigmatocystin R03114 (-)-trans-carveol:NADP+ oxidoreductase; (-)-trans-Carveol + NADP+ <=> (-)-Carvone + NADPH + H+ R03115 1,3-beta-glucan glucohydrolase; 1,3-beta-D-Glucan + H2O <=> 1,3-beta-D-Glucan + alpha-D-Glucose R03116 1,3-beta-D-oligoglucan:orthophosphate alpha-D-glucosyltransferase; 1,3-beta-D-Glucan + Orthophosphate <=> 1,3-beta-D-Glucan + D-Glucose 1-phosphate R03118 UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase; UDP-glucose + 1,3-beta-D-Glucan <=> UDP + 1,3-beta-D-Glucan R03119 propane-1,3-diol:NAD+ 1-oxidoreductase; Propane-1,3-diol + NAD+ <=> 3-Hydroxypropanal + NADH + H+ R03120 aromatic-amino-acid:2-oxoglutarate aminotransferase; Aromatic amino acid + 2-Oxoglutarate <=> Aromatic oxo acid + L-Glutamate R03121 aromatic-amino-acid:glyoxylate aminotransferase; Aromatic amino acid + Glyoxylate <=> Aromatic oxo acid + Glycine R03122 cyclomaltodextrin dextrin-hydrolase (decyclizing); Cyclomaltodextrin + H2O <=> Maltodextrin R03123 cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase; cis-3,4-Leucopelargonidin + NADP+ <=> Dihydrokaempferol + NADPH + H+ R03124 dihydrokaempferol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Dihydrokaempferol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxifolin + [Oxidized NADPH---hemoprotein reductase] + H2O R03125 dihydrokaempferol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Dihydrokaempferol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Dihydromyricetin + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R03126 dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase; Dihydrokaempferol + 2-Oxoglutarate + Oxygen <=> Kaempferol + Succinate + CO2 + H2O R03127 dihydroxyfumarate carboxy-lyase; Dihydroxyfumarate <=> 2-Hydroxy-3-oxopropanoate + CO2 R03128 Dihydroxyfumarate <=> 2-Hydroxy-3-oxosuccinate R03129 GDP-D-mannuronate:alginate D-mannuronyltransferase; GDP-D-mannuronate + (Alginate)n <=> GDP + (Alginate)n R03130 S-adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase; S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin R03131 O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase; O-Acetyl-L-serine + Uracil <=> 3-(Uracil-1-yl)-L-alanine + Acetate R03132 O-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase; O-Acetyl-L-serine + Thiosulfate <=> S-Sulfo-L-cysteine + Acetate R03133 O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine); O-Acetyl-L-serine + Zeatin <=> Lupinate + Acetate R03134 O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase; O-Acetyl-L-serine + Pyrazole <=> 3-(Pyrazol-1-yl)-L-alanine + Acetate R03135 polyvinyl-alcohol:oxygen oxidoreductase; Polyvinyl alcohol + Oxygen <=> Oxidized polyvinyl alcohol + Hydrogen peroxide R03136 polyvinyl-alcohol:(acceptor) oxidoreductase; Polyvinyl alcohol + Ferricytochrome c <=> Oxidized polyvinyl alcohol + Ferrocytochrome c + H+ R03137 coelenterazine h:oxygen 2-oxidoreductase (decarboxylating); Renilla luciferin + Oxygen <=> Oxidized Renilla luciferin + CO2 R03138 3'-phosphoadenylylsulfate:renilla luciferin sulfotransferase; 3'-Phosphoadenylyl sulfate + Renilla luciferin <=> Adenosine 3',5'-bisphosphate + Luciferyl sulfate R03139 primary-amine oxidase; 1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide R03140 D-ribulose 1,5-bisphosphate oxygenase; D-Ribulose 1,5-bisphosphate + Oxygen <=> 3-Phospho-D-glycerate + 2-Phosphoglycolate R03142 ADP:alpha-D-aldose-1-phosphate adenylyltransferase; ADP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + ADP-aldose R03143 NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase; NDP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + NDP-aldose R03145 pyruvate:ubiquinone oxidoreductase; Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2 R03146 formate:ferricytochrome-b1 oxidoreductase; Formate + 2 Ferricytochrome b1 <=> CO2 + 2 Ferrocytochrome b1 + 2 H+ R03147 L-ascorbate:ferricytochrome-b5 oxidoreductase; Ferricytochrome b5 + Ascorbate <=> Monodehydroascorbate + Ferrocytochrome b5 + H+ R03148 phosphoramidate:hexose 1-phosphotransferase; Phosphoramidate + D-Hexose <=> Ammonia + alpha-D-Hexose 1-phosphate R03149 NTP:hexose-1-phosphate nucleotidyltransferase; Nucleoside triphosphate + alpha-D-Aldose 1-phosphate <=> Diphosphate + NDP-hexose R03150 ATP:myosin-light-chain O-phosphotransferase; ATP + Myosin light chain <=> ADP + Myosin light chain phosphate R03151 [myosin-light-chain]-phosphate phosphohydrolase; Myosin light chain phosphate + H2O <=> Myosin light chain + Orthophosphate R03153 acetyl-CoA:citramalate CoA-transferase; Acetyl-CoA + (S)-2-Methylmalate <=> Acetate + (3S)-Citramalyl-CoA R03154 succinyl-CoA:(S)-citramalate CoA-transferase; Succinyl-CoA + (S)-2-Methylmalate <=> Succinate + (3S)-Citramalyl-CoA R03155 (R)-pantolactone:NADP+ oxidoreductase; (R)-Pantolactone + NADP+ <=> Dihydro-4,4-dimethyl-2,3-furandione + NADPH + H+ R03156 (R)-pantolactone:acceptor oxidoreductase (flavin-containing); (R)-Pantolactone + Acceptor <=> Dihydro-4,4-dimethyl-2,3-furandione + Reduced acceptor R03157 3-Hydroxypropionyl-CoA + Orthophosphate + ADP <=> 3-Hydroxypropanoate + CoA + ATP R03158 3-Hydroxypropanoate + CoA <=> 3-Hydroxypropionyl-CoA + H2O R03161 ATP:L-fucose 1-phosphotransferase; ATP + L-Fucose <=> ADP + L-Fucose 1-phosphate R03162 alpha-L-fucoside fucohydrolase; alpha-L-Fucoside + H2O <=> Alcohol + L-Fucose R03163 L-fucose aldose-ketose-isomerase; L-Fucose <=> L-Fuculose R03164 1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase; 6-Hydroxynicotinate + Reduced ferredoxin <=> 6-Oxo-1,4,5,6-tetrahydronicotinate + Oxidized ferredoxin R03165 hydroxymethylbilane hydro-lyase(cyclizing); Hydroxymethylbilane <=> Uroporphyrinogen III + H2O R03166 Hydroxymethylbilane <=> Uroporphyrinogen I + H2O R03167 glutathione:lipid-hydroperoxide oxidoreductase; Lipid hydroperoxide + 2 Glutathione <=> Lipid + Glutathione disulfide + 2 H2O R03168 acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase; Acetyl-CoA + N6-Hydroxy-L-lysine <=> CoA + N6-Acetyl-N6-hydroxy-L-lysine R03169 2-methyl-branched-chain-acyl-CoA:electron-transfer flavoprotein 2-oxidoreductase; 2-Methylbutanoyl-CoA + Electron-transferring flavoprotein <=> 2-Methylbut-2-enoyl-CoA + Reduced electron-transferring flavoprotein + H+ R03171 (S)-3-methyl-2-oxopentanoate:NAD+ 2-oxidoreductase (CoA-methylbutanoylating); (S)-3-Methyl-2-oxopentanoic acid + CoA + NAD+ <=> (S)-2-Methylbutanoyl-CoA + CO2 + NADH + H+ R03172 (S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase; (S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor R03174 (S)-2-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylbutanoyl)transferase; (S)-2-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine R03175 (S)-2-Methylbutanoyl-CoA <=> Branched chain fatty acid R03176 3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase; 3beta-Hydroxy-Delta5-steroid + NAD+ <=> 3-Oxo-Delta5-steroid + NADH + H+ R03177 4-guanidinobutanal:NAD+ 1-oxidoreductase; 4-Guanidinobutanal + NAD+ + H2O <=> 4-Guanidinobutanoate + NADH + H+ R03178 2-oxo-5-guanidinopentanoate carboxy-lyase; 5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2 R03180 4-guanidinobutanamide amidohydrolase; 4-Guanidinobutanamide + H2O <=> 4-Guanidinobutanoate + Ammonia R03181 4-maleylacetoacetate cis-trans-isomerase; 4-Maleylacetoacetate <=> 4-Fumarylacetoacetate R03182 7,8-diaminononanoate:carbon-dioxide cyclo-ligase; ATP + 7,8-Diaminononanoate + CO2 <=> ADP + Orthophosphate + Dethiobiotin R03183 L-gulono-1,4-lactone:NADP+ 1-oxidoreductase; L-Gulono-1,4-lactone + NADP+ <=> D-Glucuronolactone + NADPH + H+ R03184 L-gulono-1,4-lactone:oxygen 2-oxidoreductase; L-Gulono-1,4-lactone + Oxygen <=> L-xylo-Hexulonolactone + Hydrogen peroxide R03185 monodehydroascorbate:acceptor oxidoreductase; 2 Monodehydroascorbate + Acceptor <=> 2 Dehydroascorbate + Reduced acceptor R03186 2 Monodehydroascorbate <=> Dehydroascorbate + Ascorbate R03187 N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing); ATP + N-Methylhydantoin + 2 H2O <=> ADP + Orthophosphate + N-Carbamoylsarcosine R03188 N-formimino-L-aspartate iminohydrolase; N-Formimino-L-aspartate + H2O <=> N-Formyl-L-aspartate + Ammonia R03189 5-formyltetrahydrofolate:L-glutamate N-formiminotransferase; Folinic acid + L-Glutamate <=> Tetrahydrofolate + N-Formyl-L-glutamate R03190 UDPglucose:phosphopolyprenol D-glucosyltransferase; UDP-glucose + Polyprenyl phosphate <=> UDP + Polyprenylphosphate-glucose R03191 UDP-N-acetylmuramate:NADP+ oxidoreductase; UDP-N-acetylmuramate + NAD+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADH + H+ R03192 UDP-N-acetylmuramate:NADP+ oxidoreductase; UDP-N-acetylmuramate + NADP+ <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + NADPH + H+ R03193 UDP-N-acetylmuramate:L-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramate + L-Alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanine R03194 S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase; 2 S-Adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-Adenosyl-L-homocysteine + Precorrin 2 R03195 Uroporphyrinogen III + Acceptor <=> Uroporphyrin III + 6 H+ + Reduced acceptor R03197 uroporphyrinogen-III carboxy-lyase; Uroporphyrinogen III <=> Coproporphyrinogen III + 4 CO2 R03198 (R)-4-dehydropantoate:NAD+ 4-oxidoreductase; (R)-4-Dehydropantoate + NAD+ + H2O <=> (R)-3,3-Dimethylmalate + NADH + H+ R03199 (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming); (S)-2,3-Epoxysqualene <=> Lanosterol R03200 (S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming); (S)-2,3-Epoxysqualene <=> Cycloartenol R03201 (S)-2,3-Epoxysqualene <=> Triterpenoid R03202 (S)-6-hydroxynicotine:oxygen oxidoreductase; (S)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide R03203 11beta-hydroxysteroid:NADP+ 11-oxidoreductase; 11beta-Hydroxysteroid + NADP+ <=> 11-Oxosteroid + NADPH + H+ R03204 2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase; 2,5-Dihydroxypyridine + Oxygen + H2O <=> Maleamate + Formate R03206 2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating); 2-Hydroxypyridine + Reduced acceptor + Oxygen <=> 2,5-Dihydroxypyridine + Acceptor + H2O R03207 3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase; 3,5-Diiodo-L-tyrosine + 2-Oxoglutarate <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + L-Glutamate R03208 2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O R03209 6-carboxyhyxanoate:CoA ligase (AMP-forming); ATP + Pimelate + CoA <=> AMP + Diphosphate + Pimeloyl-CoA R03210 pimeloyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating); Pimeloyl-CoA + L-Alanine <=> 8-Amino-7-oxononanoate + CoA + CO2 R03211 cyclohexane-1,3-dione acylhydrolase (decyclizing); Cyclohexane-1,3-dione + H2O <=> 5-Oxohexanoic acid R03212 3-hydroxycyclohexanone:acceptor 1-oxidoreductase; 3-Hydroxycyclohexanone + Acceptor <=> Cyclohexane-1,3-dione + Reduced acceptor R03213 UDPglucose:thiohydroximate S-beta-D-glucosyltransferase; UDP-glucose + Phenylacetothiohydroximate <=> UDP + Desulfoglucotropeolin R03214 3'-phosphoadenylylsulfate:desulfoglucosinolate sulfotransferase; 3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <=> Adenosine 3',5'-bisphosphate + Glucotropaeolin R03215 formate:ferricytochrome-c-553 oxidoreductase; Formate + 2 Ferricytochrome c-553 <=> CO2 + 2 Ferrocytochrome c-553 + H+ R03216 N,6-O-disulfo-D-glucosamine 6-sulfohydrolase; N,6-O-Disulfo-D-glucosamine + H2O <=> N-Sulfo-D-glucosamine + Sulfate R03217 O-acetyl-L-homoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate R03218 procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-3-hydroxy-L-proline + Succinate + CO2 R03219 procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating); Procollagen L-proline + 2-Oxoglutarate + Oxygen <=> Procollagen trans-4-hydroxy-L-proline + Succinate + CO2 R03220 coproporphyrinogen:oxygen oxidoreductase (decarboxylating); Coproporphyrinogen III + Oxygen <=> Protoporphyrinogen IX + 2 CO2 + 2 H2O R03222 protoporphyrinogen-IX:oxygen oxidoreductase; Protoporphyrinogen IX + 3 Oxygen <=> Protoporphyrin + 3 Hydrogen peroxide R03223 2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase; 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole <=> Diphosphate + Thiamin monophosphate R03224 (3R)-3-hydroxyacyl-CoA hydro-lyase; (3R)-3-Hydroxyacyl-CoA <=> cis-2,3-Dehydroacyl-CoA + H2O R03225 (S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase; (S)-3-Hydroxybutanoate + 2-Oxoglutarate <=> Acetoacetate + (R)-2-Hydroxyglutarate R03226 16alpha-hydroxysteroid:NAD+ 16-oxidoreductase; 16alpha-Hydroxysteroid + NAD+ <=> 16-Oxosteroid + NADH + H+ R03227 16alpha-hydroxysteroid:NADP+ 16-oxidoreductase; 16alpha-Hydroxysteroid + NADP+ <=> 16-Oxosteroid + NADPH + H+ R03228 16alpha-hydroxysteroid 16-epimerase; 16alpha-Hydroxysteroid <=> 16beta-Hydroxysteroid R03229 S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase; S-Adenosyl-L-methionine + 11-O-Demethyl-17-O-deacetylvindoline <=> S-Adenosyl-L-homocysteine + Deacetylvindoline R03230 acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase; Acetyl-CoA + Deacetylvindoline <=> CoA + Vindoline R03231 S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase; S-Adenosyl-L-methionine + 8-Amino-7-oxononanoate <=> S-Adenosyl-4-methylthio-2-oxobutanoate + 7,8-Diaminononanoate R03232 protein-N(pi)-phosphohistidine:D-fructose 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Fructose <=> Protein histidine + D-Fructose 1-phosphate R03234 Sorbitol 6-phosphate + NADP+ <=> Sorbose 1-phosphate + NADPH + H+ R03236 ATP:D-tagatose-6-phosphate 1-phosphotransferase; D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP R03237 CTP:D-tagatose 6-phosphate 1-phosphotransferase; CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate R03238 UTP:D-tagatose 6-phosphate 1-phosphotransferase; UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate R03239 ITP:D-tagatose 6-phosphate 1-phosphotransferase; ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate R03240 D-galactose 6-phosphate ketol-isomerase; D-Galactose 6-phosphate <=> D-Tagatose 6-phosphate R03241 ATP:L-fuculose 1-phosphotransferase; ATP + L-Fuculose <=> ADP + L-Fuculose 1-phosphate R03243 5-amino-2-oxopentanoate:2-oxoglutarate aminotransferase; L-Histidinol phosphate + 2-Oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate R03244 L-ribulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase; L-Ribulose 5-phosphate <=> L-Xylulose 5-phosphate R03245 ATP:(R)-5-phosphomevalonate phosphotransferase; ATP + (R)-5-Phosphomevalonate <=> ADP + (R)-5-Diphosphomevalonate R03246 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing); 1,2,3-Trihydroxybenzene + Oxygen <=> gamma-Oxalocrotonate R03247 gallate carboxy-lyase; Gallate <=> 1,2,3-Trihydroxybenzene + CO2 R03249 5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O R03250 5-Amino-2-oxopentanoic acid + Urea <=> 5-Guanidino-2-oxopentanoate + H2O R03251 7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase; 7,8-Dihydro-7,8-dihydroxykynurenate + NAD+ <=> 7,8-Dihydroxykynurenate + NADH + H+ R03253 7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing); 7,8-Dihydroxykynurenate + Oxygen <=> 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate R03254 phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 3-Deoxy-D-manno-octulosonate 8-phosphate + Orthophosphate <=> Phosphoenolpyruvate + D-Arabinose 5-phosphate + H2O R03255 6-phospho-beta-D-galactoside 6-phosphogalactohydrolase; 6-Phospho-beta-D-galactoside + H2O <=> Alcohol + D-Galactose 6-phosphate R03256 lactose 6-phosphate 6-phosphogalactohydrolase; Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate R03257 L-Galactono-1,4-lactone + Acceptor <=> D-Galacturonolactone + Reduced acceptor R03258 ATP:nucleoside-5'-phosphate pyrophosphotransferase; ATP + Nucleoside 5'-phosphate <=> AMP + 5'-Phosphonucleoside 3'-diphosphate R03259 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase; 3',5'-Cyclic nucleotide + H2O <=> Nucleoside 5'-phosphate R03260 O-succinyl-L-homoserine succinate-lyase (adding cysteine); O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate R03261 (-)-trans-isopiperitenol:NAD+ oxidoreductase; (-)-trans-Isopiperitenol + NAD+ <=> (-)-Isopiperitenone + NADH + H+ R03262 corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating); Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2O R03263 18-Hydroxycorticosterone + Reduced adrenal ferredoxin + Oxygen <=> Aldosterone + Oxidized adrenal ferredoxin + 2 H2O R03264 2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase; (2E,6E)-Farnesol + NADP+ <=> 2-trans,6-trans-Farnesal + NADPH + H+ R03265 (2E,6E)-farnesol 2-cis-trans-isomerase; (2E,6E)-Farnesol <=> (2Z,6E)-Farnesol R03266 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase; 4-Hydroxy-L-glutamate + 2-Oxoglutarate <=> 4-Hydroxy-2-oxoglutarate + L-Glutamate R03267 UDPglucose:flavonol 3-O-D-glucosyltransferase; UDP-glucose + Flavonol <=> UDP + Flavonol 3-O-beta-D-glucoside R03268 UDP-D-xylose:flavonol-3-O-glycoside D-xylosyltransferase; UDP-D-xylose + Flavonol 3-O-D-glycoside <=> UDP + Flavonol 3-O-D-xylosylglycoside R03269 N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase; (R)-4'-Phosphopantothenoyl-L-cysteine <=> Pantetheine 4'-phosphate + CO2 R03270 2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate R03271 S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase; S-Adenosylmethioninamine + 1,3-Diaminopropane <=> 5'-Methylthioadenosine + Norspermidine + H+ R03273 [acetyl-CoA carboxylase] phosphate phosphohydrolase; [Acetyl-CoA carboxylase] phosphate + H2O <=> [Acetyl-CoA carboxylase] + Orthophosphate R03274 ATP:beta-adrenergic-receptor phosphotransferase; ATP + beta-Adrenergic receptor <=> ADP + Phospho-beta-adrenergic receptor R03275 (3S)-3,6-diaminohexanoate 5,6-aminomutase; (3S)-3,6-Diaminohexanoate <=> (3S,5S)-3,5-Diaminohexanoate R03276 (S)-3-hydroxybutanoyl-CoA 3-epimerase; (S)-3-Hydroxybutanoyl-CoA <=> (R)-3-Hydroxybutanoyl-CoA R03277 2-Hydroxy-3-oxopropanoate + Pyruvate <=> 2-Dehydro-3-deoxy-D-glucarate R03278 2-hydroxycyclohexan-1-one:NAD+ oxidoreductase; 2-Hydroxycyclohexan-1-one + NAD+ <=> Cyclohexane-1,2-dione + NADH + H+ R03279 trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase; trans-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH + H+ R03281 2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing); 2-Hydroxycyclohexan-1-one + Oxygen + NADPH + H+ <=> 6-Hydroxyhexan-6-olide + NADP+ + H2O R03283 4-trimethylammoniobutanal:NAD+ 1-oxidoreductase; 4-trimethylammoniobutanal:NAD+ oxidoreductase; 4-Trimethylammoniobutanal + NAD+ + H2O <=> 4-Trimethylammoniobutanoate + NADH + H+ R03284 4-Trimethylammoniobutanal + Glycine <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine R03286 N(pi)-methyl-L-histidine:beta-alanine ligase (ADP-forming); ATP + N(pi)-Methyl-L-histidine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-N(pi)-methyl-L-histidine R03288 beta-alanyl-N(pi)-methyl-L-histidine hydrolase; anserine hydrolase; beta-Alanyl-N(pi)-methyl-L-histidine + H2O <=> beta-Alanine + N(pi)-Methyl-L-histidine R03289 3'-phosphoadenylylsulfate:quercetin-3,3'-bissulfate 7-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3,3'-bissulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3',7-trissulfate R03291 trans-4-hydroxy-L-proline:NAD+ 5-oxidoreductase; Hydroxyproline + NAD+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADH + H+ R03293 trans-4-hydroxy-L-proline:NADP+ 5-oxidoreductase; Hydroxyproline + NADP+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADPH + H+ R03295 trans-4-hydroxy-L-proline:quinone oxidoreductase; Hydroxyproline + Quinone <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + Hydroquinone R03296 trans-4-hydroxy-L-proline 2-epimerase; Hydroxyproline <=> cis-4-Hydroxy-D-proline R03297 UDPglucose:gallate beta-D-glucosyltransferase; UDP-glucose + Gallate <=> UDP + 1-O-Galloyl-beta-D-glucose R03298 (2R)-2,3-bisphosphoglycerate ligase (cyclizing); 2,3-Bisphospho-D-glycerate + ATP <=> Cyclic 2,3-bisphospho-D-glycerate + ADP + Orthophosphate R03299 3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating); 3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O R03300 3,4-dihydroxyphenylacetaldehyde:NAD+ oxidoreductase; 3,4-Dihydroxyphenylacetaldehyde + NAD+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADH + H+ R03302 3,4-dihydroxyphenylacetaldehyde:NADP+ oxidoreductase; 3,4-Dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+ R03303 3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing); 3,4-Dihydroxyphenylacetate + Oxygen <=> 2-Hydroxy-5-carboxymethylmuconate semialdehyde R03304 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> S-Adenosyl-L-homocysteine + Homovanillate R03306 4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating); 4-Chlorophenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + Hydrochloric acid + NAD+ R03307 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate R03308 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); 3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Carboxy-cis,cis-muconate R03311 7-Dehydrocholesterol + hn <=> Vitamin D3 R03313 L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating); L-Glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> L-Glutamyl 5-phosphate + NADPH + H+ R03314 L-Glutamate 5-semialdehyde <=> (S)-1-Pyrroline-5-carboxylate + H2O R03315 ATP:pseudouridine 5'-phosphotransferase; ATP + Pseudouridine <=> ADP + Pseudouridine 5'-phosphate R03316 3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate R03317 UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase; UDP-N-acetyl-D-mannosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-mannosaminouronate + 2 NADH + 2 H+ R03318 GTP:alpha-D-hexose-1-phosphate gluanylyltransferase; GTP + alpha-D-Hexose 1-phosphate <=> Diphosphate + GDPhexose R03319 alpha-D-hexose 1-phosphate 1,6-phosphomutase; alpha-D-Hexose 1-phosphate <=> alpha-D-Hexose 6-phosphate R03321 beta-D-glucose 6-phosphate ketol-isomerase; beta-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate R03322 vermelone:NADP+ delta5-oxidoreductase; Vermelone + NADP+ <=> 1,3,8-Naphthalenertriol + NADPH + H+ R03323 1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase; 1-O-Sinapoyl-beta-D-glucose + (S)-Malate <=> D-Glucose + Sinapoyl malate R03325 17alpha,20alpha-dihydroxypregn-4-en-3-one:NADP+ 20-oxidoreductase; 17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+ R03326 17alpha-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); 17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O R03327 17alpha-hydroxypregnenolone:NAD+ 3-oxidoreductase; 17alpha-Hydroxypregnenolone + NAD+ <=> 17alpha-Hydroxyprogesterone + NADH + H+ R03329 steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11-hydroxylating); 17alpha-Hydroxyprogesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 21-Deoxycortisol + 2 Oxidized ferredoxin + H2O R03330 D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase; D-myo-Inositol 1,3-bisphosphate + H2O <=> Inositol 1-phosphate + Orthophosphate R03331 sn-glycero-3-phospho-1-inositol inositolphosphohydrolase; sn-Glycero-3-phospho-1-inositol + H2O <=> Glycerol + Inositol 1-phosphate R03332 1-phosphatidyl-D-myo-inositol inositolphosphohydrolase; 1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol R03333 1D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase; D-myo-Inositol 1,2-cyclic phosphate + H2O <=> Inositol 1-phosphate R03334 lysolecithin 2,3-acylmutase; 2-Acyl-sn-glycero-3-phosphocholine <=> 1-Acyl-sn-glycero-3-phosphocholine R03337 (R)-3-(4-hydroxyphenyl)lactate:NAD+ 2-oxidoreductase; (R)-3-(4-Hydroxyphenyl)lactate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADH + H+ R03339 (R)-3-(4-hydroxyphenyl)lactate:NADP+ 2-oxidoreductase; (R)-3-(4-Hydroxyphenyl)lactate + NADP+ <=> 3-(4-Hydroxyphenyl)pyruvate + NADPH + H+ R03341 4-hydroxyphenylpyruvate carboxy-lyase; 3-(4-Hydroxyphenyl)pyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2 R03342 3-(4-hydroxyphenyl)pyruvate keto-enol-isomerase; 3-(4-Hydroxyphenyl)pyruvate <=> 2-Hydroxy-3-(4-hydroxyphenyl)propenoate R03344 N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming); N,N-Dimethylaniline + Oxygen + NADPH + H+ <=> N,N-Dimethylaniline N-oxide + NADP+ + H2O R03345 N,N-dimethylaniline-N-oxide formaldehyde-lyase; N,N-Dimethylaniline N-oxide <=> N-Methylaniline + Formaldehyde R03346 nicotinate D-ribonucleotide phosphohydrolase; Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate R03347 ATP:beta-D-ribosylnicotinate 5-phosphotransferase; Nicotinate D-ribonucleotide + ADP <=> Nicotinate D-ribonucleoside + ATP R03348 nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating); Nicotinate D-ribonucleotide + Diphosphate + CO2 <=> Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate R03349 L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating); (3S,5S)-3,5-Diaminohexanoate + H2O + NAD+ <=> (S)-5-Amino-3-oxohexanoic acid + Ammonia + NADH + H+ R03350 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase; 3-Deoxy-D-manno-octulosonate 8-phosphate + H2O <=> 3-Deoxy-D-manno-octulosonate + Orthophosphate R03351 CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase; CTP + 3-Deoxy-D-manno-octulosonate <=> Diphosphate + CMP-3-deoxy-D-manno-octulosonate R03352 3-hydroxy-2-methylpropanoyl-CoA hydrolase; 3-Hydroxy-2-methylpropanoyl-CoA + H2O <=> 3-Hydroxy-2-methylpropanoate + CoA R03353 5alpha-cholest-7-en-3beta-ol delta7-delta8-isomerase; Lathosterol <=> 5alpha-Cholest-8-en-3beta-ol R03354 UDP-alpha-D-galactose:beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase; Glucosylceramide + UDP-alpha-D-galactose <=> Lactosylceramide + UDP R03355 beta-D-galactosyl-1,4-beta-D-glucosylceramide galactohydrolase; Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose R03356 dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase; Dolichyl D-xylosyl phosphate + [Protein]-L-serine <=> Dolichyl phosphate + D-Xylosylprotein R03357 1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase; 1-Palmitoylglycerol 3-phosphate + NADP+ <=> Palmitoylglycerone phosphate + NADPH + H+ R03358 1-(4-hydroxyphenyl)-2-aminoethanol hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]; octopamine hydro-lyase (deaminating); Octopamine <=> 4-Hydroxyphenylacetaldehyde + Ammonia R03359 (R)-synephrine hydro-lyase (methylamine-forming); (-)-Sympatol <=> 4-Hydroxyphenylacetaldehyde + Methylamine R03360 1-phosphatidyl-D-myo-inositol 2-acylhydrolase; 1-Phosphatidyl-D-myo-inositol + H2O <=> 1-Acylglycerophosphoinositol + Carboxylate R03361 ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate R03362 ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate R03363 1-phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate R03364 1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming); 1-Phosphatidyl-D-myo-inositol <=> D-myo-Inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol R03365 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing); Caffeate + Oxygen <=> 3-(2-Carboxyethenyl)-cis,cis-muconate R03366 S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; S-Adenosyl-L-methionine + Caffeate <=> S-Adenosyl-L-homocysteine + Ferulate R03367 Caffeate <=> 3,4-Dihydroxystyrene + CO2 R03369 3-(2-hydroxyphenyl)propanoate,NADH2:oxygen oxidoreductase(3-hydroxylating); 3-(2-Hydroxyphenyl)propanoate + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NAD+ + H2O R03370 stearoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating); Octadecanoyl-[acyl-carrier protein] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Oleoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R03371 myo-inositol-hexakisphosphate 3-phosphohydrolase; Phytic acid + H2O <=> D-myo-Inositol 1,2,4,5,6-pentakisphosphate + Orthophosphate R03372 myo-inositol-hexakisphosphate 4-phosphohydrolase; Phytic acid + H2O <=> Inositol 1,2,3,5,6-pentakisphosphate + Orthophosphate R03373 4-hydroxyphenyllactate:NAD+ oxidoreductase; (R)-3-(3,4-Dihydroxyphenyl)lactate + NAD+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADH + H+ R03374 caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyltransferase; Caffeoyl-CoA + (R)-3-(3,4-Dihydroxyphenyl)lactate <=> CoA + Rosmarinate R03375 CTP:N-methylethanolamine-phosphate cytidylyltransferase; CTP + N-Methylethanolamine phosphate <=> Diphosphate + CDP-N-methylethanolamine R03376 [procollagen]-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating); Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2 R03378 GTP:5-hydroxy-L-lysine O-phosphotransferase; GTP + L-Hydroxylysine <=> GDP + 5-Phosphooxy-L-lysine R03380 UDP-alpha-D-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase; UDP-alpha-D-galactose + Procollagen 5-hydroxy-L-lysine <=> UDP + 5-(D-Galactosyloxy)-L-lysine-procollagen R03381 (S)-Methylmalonate semialdehyde + CoA + NAD+ <=> (R)-Methylmalonyl-CoA + NADH + H+ R03383 methylmalonate:CoA ligase (AMP-forming); Methylmalonate + CoA + ATP <=> (R)-Methylmalonyl-CoA + AMP + Diphosphate R03384 ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase; ATP + 1-Amino-1-deoxy-scyllo-inositol <=> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate R03385 3-hydroxy-2-methylpyridine-5-carboxylate,NADH:oxygen oxidoreductase (ring-opening); 3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADH + H+ <=> 2-(Acetamidomethylene)succinate + NAD+ R03386 3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (ring-opening); 3-Hydroxy-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Acetamidomethylene)succinate + NADP+ R03387 ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase; ATP + 2-Dehydro-3-deoxy-D-galactonate <=> ADP + 2-Dehydro-3-deoxy-6-phospho-D-galactonate R03388 5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase; 5,6,7,8-Tetrahydromethanopterin + NADP+ <=> 7,8-Dihydromethanopterin + H+ + NADPH R03390 formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase; Formylmethanofuran + 5,6,7,8-Tetrahydromethanopterin <=> Methanofuran + 5-Formyl-5,6,7,8-tetrahydromethanopterin R03391 CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD+ 3-oxydoreductase; CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ R03392 CDP-4-dehydro-3,6-dideoxy-D-glucose:NADP+ 3-oxydoreductase; CDP-4-dehydro-3,6-dideoxy-D-glucose + NADP+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ R03393 D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase; 1D-myo-Inositol 1,4-bisphosphate + H2O <=> myo-Inositol 4-phosphate + Orthophosphate R03394 D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase; D-myo-Inositol 1,4,5-trisphosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + Orthophosphate R03395 ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase; ATP + Dihydrostreptomycin 6-phosphate <=> ADP + Dihydrostreptomycin 3'alpha,6-bisphosphate R03396 GDP-6-deoxy-D-talose:NAD+ 4-oxidoreductase; GDP-6-deoxy-D-talose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+ R03397 GDP-6-deoxy-D-mannose:NAD+ 4-oxidoreductase; GDP-6-deoxy-D-mannose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+ R03398 GDP-6-deoxy-D-talose:NADP+ 4-oxidoreductase; GDP-6-deoxy-D-talose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ R03399 GDP-6-deoxy-D-mannose:NADP+ 4-oxidoreductase; GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ R03401 (9S,13S)-10,11-dihydro-12-oxo-15-phytoenoate:NADP+ 4-oxidoreductasee; (9S,13S,15Z)-12-Oxo-10,11-dihydrophyto-15-enoate + NADP+ <=> (9S,13S,15Z)-12-Oxophyto-10,15-dienoate + NADPH + H+ R03402 (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase; (9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid <=> (9S,13S,15Z)-12-Oxophyto-10,15-dienoate R03404 3beta-hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase; Dehydroepiandrosterone sulfate + H2O <=> Dehydroepiandrosterone + Sulfate R03405 3'-phosphoadenylylsulfate:alcohol sulfotransferase; 3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate R03406 androst-5-ene-3beta,17beta-diol:NAD+ oxidoreductase; Androstenediol + NAD+ <=> Dehydroepiandrosterone + NADH + H+ R03407 androst-5-ene-3beta,17beta-diol:NADP+ oxidoreductase; Androstenediol + NADP+ <=> Dehydroepiandrosterone + NADPH + H+ R03408 Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O R03409 guanosine 3'-diphosphate 5'-triphosphate 5'-phosphohydrolase; Guanosine 3'-diphosphate 5'-triphosphate + H2O <=> Guanosine 3',5'-bis(diphosphate) + Orthophosphate R03410 S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating); S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid methylene fatty acid R03411 S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing); S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid <=> S-Adenosyl-L-homocysteine + Phospholipid cyclopropane fatty acid R03415 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase; 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> Aldehyde + sn-Glycero-3-phosphoethanolamine R03416 1-acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase; 1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine R03417 L-2-lysophosphatidylethanolamine aldehydohydrolase; 2-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine R03418 1-alpha-D-galactosyl-myo-inositol:raffinose galactosyltransferase; alpha-D-Galactosyl-(1->3)-1D-myo-inositol + Raffinose <=> myo-Inositol + Stachyose R03421 N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase; N4-(Acetyl-beta-D-glucosaminyl)asparagine + H2O <=> N-Acetyl-beta-D-glucosaminylamine + L-Aspartate R03422 nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase; 2',3'-Cyclic nucleotide + H2O <=> Nucleoside 2'-phosphate R03423 nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase; 2',3'-Cyclic nucleotide + H2O <=> Nucleoside 3'-phosphate R03424 S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine R03425 glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating); Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2 R03427 D-myo-inositol 1,3,4-trisphosphate 1-phosphohydrolase; 1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 3,4-bisphosphate + Orthophosphate R03428 ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate R03429 ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate R03430 D-myo-inositol 1,3,4,5-tetrakisphosphate 5-phosphohydrolase; 1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-Inositol 1,3,4-trisphosphate + Orthophosphate R03431 3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase; 3-(3,5-Diiodo-4-hydroxyphenyl)lactate + NAD+ <=> 3,5-Diiodo-4-hydroxyphenylpyruvate + NADH + H+ R03433 ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase; ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate R03434 D-myo-inositol 1,3,4,5-tetrakisphosphate 3-phosphohydrolase; 1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + Orthophosphate R03435 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol R03437 acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase; Acetyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine R03438 acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase; Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine R03439 kynurenate:oxygen oxidoreductase (hydroxylating); 4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NAD+ R03440 kynurenate:oxygen oxidoreductase (hydroxylating); 4-Hydroxy-2-quinolinecarboxylic acid + Oxygen + NADPH + H+ <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NADP+ R03441 kynurenate,acceptor:oxygen oxidoreductase (hydroxylating); 4-Hydroxy-2-quinolinecarboxylic acid + Reduced acceptor + Oxygen <=> 7,8-Dihydro-7,8-dihydroxykynurenate + Acceptor R03443 N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphrylating); N-Acetyl-L-glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> N-Acetyl-L-glutamate 5-phosphate + NADPH + H+ R03444 (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase; (R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O R03445 4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O R03446 ADP-D-ribosyl-[dinitrogen reductase] ADP-ribosylhydrolase; ADP-D-ribosyl-[dinitrogen reductase] + H2O <=> [Dinitrogen reductase] + ADP-ribose R03447 NAD+:[dinitrogen reductase](ADP-D-ribosyl)transferase; NAD+ + [Dinitrogen reductase] <=> Nicotinamide + ADP-D-ribosyl-[dinitrogen reductase] R03448 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase; 1,8-Diazacyclotetradecane-2,9-dione + H2O <=> N-(6-Aminohexanoyl)-6-aminohexanoate R03449 ATP:[pyruvate dehydrogenase (lipoamide)] phosphotransferase; ATP + [Pyruvate dehydrogenase (acetyl-transferring)] <=> ADP + [Pyruvate dehydrogenase (acetyl-transferring)] phosphate R03450 [pyruvate dehydrogenase (lipoamide)]-phosphate phosphohydrolase; [Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O <=> [Pyruvate dehydrogenase (acetyl-transferring)] + Orthophosphate R03451 N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); N6,N6,N6-Trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinate + CO2 R03452 (6aR,11aR)-3,9-dihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6a-hydroxylating); 3,9-Dihydroxypterocarpan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3,6,9-Trihydroxypterocarpan + [Oxidized NADPH---hemoprotein reductase] + H2O R03454 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase; 2-Acetyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acetyl-sn-glycerol + Orthophosphate R03455 acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase; Acetyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphate R03456 S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase; S-Adenosyl-L-methionine + 3,7-Di-O-methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7,4'-Tri-O-methylquercetin R03457 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase; D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O R03458 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase; 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + NADP+ <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + NADPH + H+ R03459 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase; 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phosphoribosylamino)uracil + Ammonia R03460 phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase; Phosphoenolpyruvate + Shikimate 3-phosphate <=> Orthophosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate R03461 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase; 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate <=> 3-Hydroxy-2-methylpyridine-5-carboxylate + CO2 R03462 biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing); Biphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate R03463 2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase; 2,6-Dioxo-6-phenylhexanoate + NADP+ <=> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+ R03464 5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing); 5,10-Methenyltetrahydromethanopterin + H2O <=> 5-Formyl-5,6,7,8-tetrahydromethanopterin + H+ R03465 (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase; (3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate R03466 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing); 1-Hydroxy-2-naphthoate + Oxygen <=> (3E)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate R03467 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase; 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O <=> 3-beta-D-Galactosyl-sn-glycerol + 2 Carboxylate R03468 CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> CMP + 1,2-Diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol R03469 ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase; ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate R03470 4-carboxymuconolactone carboxy-lyase; 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate + CO2 R03471 ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase; ATP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine <=> ADP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine R03472 5-amino-1-(5-phospho-D-ribosyl)imidazole formate-lyase (decarboxylating, 4-amino-2-methyl-5-phosphomethylpyrimidine-forming); Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO R03473 ATP:[L-glutamate:ammonia ligase (ADP-forming)] adenylyltransferase; ATP + [L-Glutamate:ammonia ligase (ADP-forming)] <=> Diphosphate + Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] R03474 [L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine:phosphate adenylyltransferase; Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + Orthophosphate <=> ADP + [L-Glutamate:ammonia ligase (ADP-forming)] R03475 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase; 1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD+ <=> 1-Acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH + H+ R03476 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NADH:oxygen oxidoreductase (12-hydroxylating); 1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + Oxygen + NADH + H+ <=> 1-Acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ + H2O R03477 L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amindinotransferase; L-Arginine + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate <=> L-Ornithine + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate R03478 ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate R03479 ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase; ATP + 1D-myo-Inositol 3,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate R03482 N-acetyl-D-glucosaminylphosphatidylinositol acetyhydrolase; N-Acetyl-D-glucosaminylphosphatidylinositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + Acetate R03486 UDP-alpha-D-galactose:beta-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide 4II-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + Lactosylceramide <=> UDP + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide R03488 CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3 R03489 CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide R03490 UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl--D-glucosylceramide N-acetyl-D-galactrosaminyltransferase; UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2 R03491 Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O R03492 GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer (GA2) N-acetylhexosaminohydrolase; GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine R03493 3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA hydro-lyase; 3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O R03494 geranoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Geranoyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA R03495 12beta-hydroxysteroid:NADP+ 12-oxidoreductase; 3alpha,7alpha,12beta-Trihydroxy-5beta-cholanate + NADP+ <=> 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate + NADPH + H+ R03496 1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase; 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-Guanidino-1-deoxy-scyllo-inositol + Orthophosphate R03497 5-O-methyl-myo-inositol:NAD+ oxidoreductase; 5-O-Methyl-myo-inositol + NAD+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+ R03498 D-pinitol:NADP+ oxidoreductase; D-Pinitol + NADP+ <=> 2D-5-O-Methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+ R03502 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase; 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol + Pyruvate <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-Alanine R03503 ATP:6-hydroxymethyl-7,8-dihydropterin 6'-diphosphotransferase; ATP + 6-(Hydroxymethyl)-7,8-dihydropterin <=> AMP + 6-Hydroxymethyl-7,8-dihydropterin diphosphate R03504 7,8-dihydroneopterin glycolaldehyde-lyase [6-(hydroxymethyl)-7,8-dihydropterin-forming]; 7,8-Dihydroneopterin <=> Glycolaldehyde + 6-(Hydroxymethyl)-7,8-dihydropterin R03506 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase; 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + NADH + H+ R03507 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 Oxidized adrenal ferredoxin R03508 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase(cyclizing); 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <=> Indoleglycerol phosphate + CO2 + H2O R03509 N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase; N-(5-Phospho-D-ribosyl)anthranilate <=> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate R03510 phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing); Phylloquinone + Reduced acceptor + Oxygen <=> Vitamin K1 epoxide + Acceptor + H2O R03511 phylloquinone:oxidized-dithiothreitol oxidoreductase; Phylloquinone + Oxidized dithiothreitol + H2O <=> Vitamin K1 epoxide + Dithiothreitol R03512 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase; 3-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol R03513 UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-alpha-D-galactosaminyl-polypeptide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R R03514 UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->6)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-N-acetyl-alpha-D-galactosaminyl-R R03515 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphate phosphohydrolase; [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H2O <=> [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] + Orthophosphate R03516 ATP:[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphotransferase; ATP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] <=> ADP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate R03517 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase; 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate R03518 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase; 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + Sulfate R03519 GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + beta-D-Galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosaminyl-R R03520 (5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase; Prostaglandin I2 + NADP+ <=> (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H+ R03521 Prostaglandin I2 + H2O <=> 6-Keto-prostaglandin F1alpha R03522 RX:glutathione R-transferase; RX + Glutathione <=> Halide + R-S-Glutathione R03523 bromochloromethane halidohydrolase; Bromochloromethane + H2O <=> Formaldehyde + Bromide + Cl- + 2 H+ R03524 L-cysteine hydrogen-sulfide-lyase (adding HCN); L-Cysteine + Hydrogen cyanide <=> Hydrogen sulfide + 3-Cyano-L-alanine R03526 UDP-glucose:beta-D-glucosyltransferase (acceptor-unspecific); UDP-glucose + ROH <=> UDP + beta-D-Glucoside R03527 D-glucoside glucohydrolase; beta-D-Glucoside + H2O <=> D-Glucose + ROH R03528 L-cysteine-S-conjugate aryl-thiol-lyase (deaminating; pyruvate-forming); L-Cysteine-S-conjugate + H2O <=> Aryl thiol + Ammonia + Pyruvate R03529 alkylmercury mercuric-lyase (alkane-forming); Alkylmercury + H+ <=> Alkane + Mercury(2+) R03530 ATP:dIDP phosphotransferase; ATP + dIDP <=> ADP + dITP R03531 2'-deoxyinosine-5'-triphosphate pyrophosphohydrolase; dITP diphosphohydrolase (diphosphate-forming); dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate R03532 donor:hydrogen-peroxide oxidoreductase; Reduced acceptor + Hydrogen peroxide <=> Acceptor + 2 H2O R03533 donor:sulfur oxidoreductase; Sulfur + Reduced acceptor <=> Hydrogen sulfide + Acceptor R03534 2-hydroxyglutarate:(acceptor) 2-oxidoreductase; 2-Hydroxyglutarate + FAD <=> 2-Oxoglutarate + FADH2 R03535 PQQH2 + Propynoate <=> 2-Propynal + PQQ + H2O R03537 2',3'-cyclic AMP 3'-nucleotidohydrolase; 2',3'-Cyclic AMP + H2O <=> 3'-AMP R03538 2',3'-cyclic UMP 3'-nucleotidohydrolase; 2',3'-Cyclic UMP + H2O <=> 3'-UMP R03539 Hydroiodic acid + 3-Iodo-L-tyrosine <=> Iodine + L-Tyrosine R03540 maleamate amidohydrolase; Maleic acid + Ammonia <=> Maleamate + H2O R03541 prenyl-diphosphate diphosphohydrolase; Prenyl diphosphate + H2O <=> Prenol + Diphosphate R03542 alpha-aminopropiononitrile aminohydrolase; alpha-Aminopropiononitrile + 2 H2O <=> Alanine + Ammonia R03543 benzene,NADH:oxygene 1,2-oxidoreductase; Benzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydrobenzene-1,2-diol + NAD+ R03544 Butanal + NADH + H+ <=> 1-Butanol + NAD+ R03545 Butanal + NADPH + H+ <=> 1-Butanol + NADP+ R03546 carbamate hydro-lyase; cyanate hydratase; cyanate C-N-lyase; Cyanate + H+ + HCO3- <=> CO2 + Carbamate R03547 UDPglucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase; UDP-glucose + Methylazoxymethanol <=> UDP + Cycasin R03548 UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase; UDP-glucose + 7,8-Dihydroxycoumarin <=> UDP + Daphnin R03549 gallate:oxygen 3,4-oxidoreductase (decyclizing); Gallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + H2O R03550 gallate:oxygen 4,5-oxidoreductase (decyclizing); Gallate + Oxygen <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate R03551 Gallate + Methanol <=> 3-O-Methylgallate + H2O R03552 acetyl-CoA:histone acetyltransferase; Acetyl-CoA + Histone-L-lysine <=> CoA + Histone N6-acetyl-L-lysine R03553 3'-phosphoadenylylsulfate:keratan 6'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Keratan sulfate <=> Adenosine 3',5'-bisphosphate + Keratan sulfate R03554 S-adenosyl-L-methionine:loganate 11-O-methyltransferase; S-Adenosyl-L-methionine + Loganate <=> S-Adenosyl-L-homocysteine + Loganin R03555 loganin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ring-cleaving); Loganin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Secologanin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R03556 7-deoxyloganin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating); Deoxyloganin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Loganin + [Oxidized NADPH---hemoprotein reductase] + H2O R03557 secondary alcohol:NADP+ oxidoreductase; Secondary alcohol + NADP+ <=> Ketone + NADPH + H+ R03558 UDPglucose:salicyl-alcohol beta-D-glucosyltransferase; UDP-glucose + Salicyl alcohol <=> UDP + Salicin R03559 toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating); Toluene + Oxygen + NADH + H+ <=> Toluene-cis-dihydrodiol + NAD+ R03560 toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating); Toluene + Oxygen + NADH + H+ <=> o-Cresol + NAD+ + H2O R03562 toluene,NADPH:oxogen oxidoreductase (3-hydroxylating); Toluene + Oxygen + NADPH + H+ <=> 3-Cresol + NADP+ + H2O R03563 atropine acylhydrolase; Atropine + H2O <=> Tropine + Tropate R03564 Tropate + Tropine <=> L-Hyoscyamine + H2O R03565 UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase; UDP-glucose + Vitexin <=> Vitexin 2''-O-beta-D-glucoside + UDP R03566 3-cresol,NADPH:oxogen oxidoreductase (2-hydroxylating); 3-Cresol + Oxygen + NADPH + H+ <=> 2,3-Dihydroxytoluene + NADP+ + H2O R03567 6-methylsalicylate carboxy-lyase; 6-Methylsalicylate <=> 3-Cresol + CO2 R03568 4-cresol,NADPH:oxogen oxidoreductase (2-hydroxylating); 4-Cresol + Oxygen + NADPH + H+ <=> 4-Methylcatechol + NADP+ + H2O R03570 ADP-sugar sugarphosphohydrolase; ADP-sugar + H2O <=> AMP + alpha-D-Aldose 1-phosphate R03571 S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase; S-Adenosyl-L-methionine + Apigenin <=> S-Adenosyl-L-homocysteine + Acacetin R03572 allyl-alcohol:NADP+ oxidoreductase; Allyl alcohol + NADP+ <=> Acrolein + NADPH + H+ R03573 UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase; UDP-glucose + Alizarin <=> UDP + 1-Hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone R03574 UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase; UDP-glucose + Apigenin <=> UDP + Apigenin 7-O-beta-D-glucoside R03575 chlorite:acceptor oxidoreductase; Chloric acid + Reduced acceptor <=> Chlorous acid + Acceptor + H2O R03576 ATP:D-allose 6-phosphotransferase; ATP + D-Allose <=> ADP + D-Allose 6-phosphate R03577 D-apiitol:NAD+ 1-oxidoreductase; D-Apiitol + NAD+ <=> D-Apiose + NADH + H+ R03579 N-feruloylglycine amidohydrolase; N-Feruloylglycine + H2O <=> Ferulate + Glycine R03581 geraniol:NADP+ oxidoreductase; Geraniol + NADP+ <=> Geranial + NADPH + H+ R03582 indan-1-ol:NAD+ 1-oxidoreductase; Indan-1-ol + NAD+ <=> Indanone + NADH + H+ R03583 indan-1-ol:NADP+ 1-oxidoreductase; Indan-1-ol + NADP+ <=> Indanone + NADPH + H+ R03584 L-glycol:NAD+ oxidoreductase; L-Glycol + NAD+ <=> 2-Hydroxycarbonyl compound + NADH + H+ R03585 L-glycol:NADP+ oxidoreductase; L-Glycol + NADP+ <=> 2-Hydroxycarbonyl compound + NADPH + H+ R03586 L-xylose:NADP+ 1-oxidoreductase; L-Xylose + NADP+ <=> L-Xylono-1,4-lactone + NADPH + H+ R03587 S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase; S-Adenosyl-L-methionine + Luteolin <=> S-Adenosyl-L-homocysteine + Chrysoeriol R03588 UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase; UDP-glucose + Luteolin <=> UDP + Luteolin 7-O-beta-D-glucoside R03589 UDPglucuronate:luteolin 7-O-glucuronosyltransferase; UDP-glucuronate + Luteolin <=> UDP + Luteolin 7-O-glucuronide R03590 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Eriodictyol + 2-Oxoglutarate + Oxygen <=> Luteolin + Succinate + CO2 + H2O R03591 morphine:NAD+ 6-oxidoreductase; Morphine + NAD+ <=> Morphinone + NADH + H+ R03592 morphine:NAD(P)+ 6-oxidoreductase; Morphine + NADP+ <=> Morphinone + NADPH + H+ R03593 ricinine aminohydrolase; Ricinine + 2 H2O <=> 3-Carboxy-4-methoxy-N-methyl-2-pyridone + Ammonia R03594 UDPglucose:scopoletin O-beta-D-glucosyltransferase; UDP-glucose + Scopoletin <=> UDP + Scopolin R03595 ATP:selenide, water phosphotransferase; ATP + Hydrogen selenide + H2O <=> AMP + Selenophosphoric acid + Orthophosphate R03596 hydrogen selenide:NADP+ oxidoreductase; Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+ R03597 hydrogen-selenide:(acceptor) oxidoreductase; Hydrogen selenide + 3 Acceptor + 3 H2O <=> Selenite + 3 Reduced acceptor + 2 H+ R03599 L-selenocysteine selenide-lyase (L-alanine-forming); L-Selenocysteine + Reduced acceptor <=> Hydrogen selenide + L-Alanine + Acceptor R03600 hydrogen-sulfide:ferredoxin oxidoreductase; Hydrogen selenide + 6 Oxidized ferredoxin + 3 H2O <=> Selenite + 6 Reduced ferredoxin + 8 H+ R03601 O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide); O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate R03602 Selenium <=> Selenite R03603 Selenium <=> Selenate R03604 syringin beta-D-glucosidase; Syringin + H2O <=> Sinapyl alcohol + D-Glucose R03605 UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase; UDP-glucose + Sinapyl alcohol <=> UDP + Syringin R03607 ATP:viomycin O-phosphotransferase; ATP + Viomycin <=> ADP + O-Phosphoviomycin R03608 o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating); o-Cresol + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + H2O R03609 (gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase; Agaritine + Acceptor <=> 4-Hydroxymethylphenylhydrazine + gamma-L-Glutamyl-acceptor R03610 calcidiol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating); Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitriol + Oxidized adrenal ferredoxin + H2O R03611 calciol,NADPH-hemoprotein reductase:oxygen oxidoreductase (25-hydroxylating); Calcidiol + [Oxidized NADPH---hemoprotein reductase] + H2O <=> Vitamin D3 + [Reduced NADPH---hemoprotein reductase] + Oxygen R03612 cetraxate-benzyl-ester benzylhydrolase; Cetraxate benzyl ester + H2O <=> Cetraxate + Benzyl alcohol R03613 diphthine:ammonia ligase (AMP-forming); ATP + Peptide diphthine + Ammonia + H+ <=> AMP + Diphosphate + Peptide diphthamide R03614 (-)-ephedrine:NAD+ 2-oxidoreductase; Ephedrine + NAD+ <=> (R)-2-Methylimino-1-phenylpropan-1-ol + NADH + H+ R03615 flavonoid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Flavonoid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxyflavonoid + [Oxidized NADPH---hemoprotein reductase] + H2O R03616 galactosylglycerol galactohydrolase; 3-beta-D-Galactosyl-sn-glycerol + H2O <=> Galactose + Glycerol R03617 D-galactosyl-N-acylsphingosine galactohydrolase; Galactosylceramide + H2O <=> D-Galactose + N-Acylsphingosine R03618 globotriosylceramide galactohydrolase; alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> D-Galactose + Lactosylceramide R03620 N-methylhexanamide amidohydrolase; N-Methylhexanamide + H2O <=> Hexanoic acid + Methylamine R03621 acetyl-CoA:imidazole N-acetyltransferase; Acetyl-CoA + Imidazole <=> CoA + N-Acetylimidazole R03622 kievitone-hydrate hydro-lyase; Kievitone hydrate <=> Kievitone + H2O R03623 S-adenosyl-L-methionine:licodione 2'-O-methyltransferase; S-Adenosyl-L-methionine + Licodione <=> S-Adenosyl-L-homocysteine + 2'-O-Methyllicodione R03624 limonoate-D-ring-lactone lactonohydrolase; Limonoate D-ring-lactone + H2O <=> Limonoate R03625 UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase; UDP-glucose + Acetone cyanohydrin <=> UDP + Linamarin R03626 linoleate:oxygen 13-oxidoreductase; Linoleate + Oxygen <=> (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid R03627 9-cis,12-cis-octadecadienoate delta12-cis-delta11-trans-isomerase; Linoleate <=> Rumenic acid R03628 melatonin:oxygen 2,3-dioxygenase (indole-decyclizing); Melatonin + Oxygen <=> Formyl-N-acetyl-5-methoxykynurenamine R03629 melatonin,NADPH---hemoprotein reductase:oxygen oxidoreductase; Melatonin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxymelatonin + [Oxidized NADPH---hemoprotein reductase] + H2O R03630 phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating); Phthalate + Oxygen + NADH + H+ <=> cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ R03631 phytanate:CoA ligase (AMP-forming); ATP + Phytanate + CoA <=> AMP + Diphosphate + Phytanoyl-CoA R03632 ATP:protamine O-phosphotransferase; ATP + Protamine <=> ADP + O-Phosphoprotamine R03633 S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase; S-Adenosyl-L-methionine + O-Demethylpuromycin <=> S-Adenosyl-L-homocysteine + Puromycin R03634 Stachyose + H2O <=> Raffinose + D-Galactose R03635 stachyose fructohydrolase; Stachyose + H2O <=> D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + D-Fructose R03636 leucocyanidin:NADP+ 4-oxidoreductase; Leucocyanidin + NADP+ <=> Taxifolin + NADPH + H+ R03637 taxifolin,NADH:oxygen oxidoreductase (8-hydroxylating); Taxifolin + Oxygen + NADH + H+ <=> 2,3-Dihydrogossypetin + NAD+ + H2O R03638 taxifolin,NADPH:oxygen oxidoreductase (8-hydroxylating); Taxifolin + Oxygen + NADPH + H+ <=> 2,3-Dihydrogossypetin + NADP+ + H2O R03639 taxifolin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Taxifolin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Dihydromyricetin + [Oxidized NADPH---hemoprotein reductase] + H2O R03640 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Eriodictyol + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2 R03641 testololactone lactonohydrolase; Testololactone + H2O <=> Testolate R03642 Vicianose + Mandelonitrile <=> Vicianin + H2O R03643 NADH:(quinone-acceptor) oxidoreductase; Vitamin K + NADH + H+ <=> Reduced Vitamin K + NAD+ R03645 vitamin K:oxidized-dithiothreitol oxidoreductase; Vitamin K + Oxidized dithiothreitol + H2O <=> Vitamin K epoxide + Dithiothreitol R03646 L-arginine:tRNA(Arg) ligase (AMP-forming); ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg) R03647 L-aspartate:tRNAAsp ligase (AMP-forming); ATP + L-Aspartate + tRNA(Asn) <=> AMP + Diphosphate + L-Aspartyl-tRNA(Asn) R03648 L-asparagine:tRNA(Asn) ligase (AMP-forming); ATP + L-Asparagine + tRNA(Asn) <=> AMP + Diphosphate + L-Asparaginyl-tRNA(Asn) R03650 L-cysteine:tRNA(Cys) ligase (AMP-forming); ATP + L-Cysteine + tRNA(Cys) <=> AMP + Diphosphate + L-Cysteinyl-tRNA(Cys) R03651 L-glutamate:tRNA(Gln) ligase (AMP-forming); ATP + L-Glutamate + tRNA(Gln) <=> AMP + Diphosphate + L-Glutamyl-tRNA(Gln) R03652 L-glutamine:tRNA(Gln) ligase (AMP-forming); ATP + L-Glutamine + tRNA(Gln) <=> AMP + Diphosphate + Glutaminyl-tRNA R03654 glycine:tRNA(Gly) ligase (AMP-forming); ATP + Glycine + tRNA(Gly) <=> AMP + Diphosphate + Glycyl-tRNA(Gly) R03655 L-histidine:tRNA(His) ligase (AMP-forming); ATP + L-Histidine + tRNA(His) <=> AMP + Diphosphate + L-Histidyl-tRNA(His) R03656 L-isoleucine:tRNA(Ile) ligase (AMP-forming); ATP + L-Isoleucine + tRNA(Ile) <=> AMP + Diphosphate + L-Isoleucyl-tRNA(Ile) R03657 L-leucine:tRNA(Leu) ligase (AMP-forming); ATP + L-Leucine + tRNA(Leu) <=> AMP + Diphosphate + L-Leucyl-tRNA R03658 L-lysine:tRNALys ligase (AMP-forming); ATP + L-Lysine + tRNA(Lys) <=> AMP + Diphosphate + L-Lysyl-tRNA R03659 L-methionine:tRNAMet ligase (AMP-forming); ATP + L-Methionine + tRNA(Met) <=> AMP + Diphosphate + L-Methionyl-tRNA R03660 L-phenylalanine:tRNA(Ala) ligase (AMP-forming); ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe) R03661 L-proline:tRNA(Pro) ligase (AMP-forming); ATP + L-Proline + tRNA(Pro) <=> AMP + Diphosphate + L-Prolyl-tRNA(Pro) R03662 L-serine:tRNA(Ser) ligase (AMP-forming); ATP + L-Serine + tRNA(Ser) <=> AMP + Diphosphate + L-Seryl-tRNA(Ser) R03663 L-threonine:tRNA(Thr) ligase (AMP-forming); ATP + L-Threonine + tRNA(Thr) <=> AMP + Diphosphate + L-Threonyl-tRNA(Thr) R03664 L-tryptophan -tRNA(Trp) ligase (AMP-forming); ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp) R03665 L-valine:tRNAVal ligase (AMP-forming); ATP + L-Valine + tRNA(Val) <=> AMP + Diphosphate + L-Valyl-tRNA(Val) R03666 Cadaverine <=> Piperideine R03667 coformycin:NADP+ 8-oxidoreductase; Coformycin + NADP+ <=> 8-Oxocoformycin + NADPH + H+ R03668 acetyl-CoA:thioethanolamine S-acetyltransferase; Acetyl-CoA + Cysteamine <=> CoA + S-Acetylthioethanolamine R03671 D-fuconate hydro-lyase; D-Fuconate <=> 2-Dehydro-3-deoxy-D-fuconate + H2O R03672 L-Dopachrome + 3,4-Dihydroxy-L-phenylalanine <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Dopaquinone R03673 L-dopachrome delta7-delta2-isomerase; L-Dopachrome <=> 5,6-Dihydroxyindole-2-carboxylate R03674 L-Dopachrome <=> 5,6-Dihydroxyindole + CO2 R03675 5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase; 5alpha-Ergosta-7,22-diene-3beta,5-diol <=> Ergosterol + H2O R03677 Ergosterol + hn <=> Vitamin D2 R03678 (3Z)-phytochromobilin:ferredoxin oxidoreductase; (3Z)-Phytochromobilin + 2 Oxidized ferredoxin <=> Biliverdin + 2 Reduced ferredoxin R03679 UDP-alpha-D-galactose:galactogen 6-beta-D-galactosyltransferase; UDP-alpha-D-galactose + Galactogen <=> UDP + (1->6)-beta-D-Galactosylgalactogen R03680 UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase; UDP-glucose + Gibberellin A3 <=> UDP + Gibberellin 2-O-beta-D-glucoside R03681 UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase; UDP-glucose + Glycogenin <=> UDP + alpha-D-Glucosylglycogenin R03682 Hemoglobin + Oxygen <=> Oxyhemoglobin R03684 Hemoglobin <=> Globin + Heme R03685 bis-D-fructose-2',1:2,1'-dianhydride fructohydrolase; Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose R03686 UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase; UDP-glucose + Isovitexin <=> Isovitexin 2''-O-beta-D-glucoside + UDP R03687 2-quinolinecarboxylic acid:acceptor 4-oxidoreductase (hydroxylating); 2-Quinolinecarboxylic acid + Acceptor + H2O <=> 4-Hydroxy-2-quinolinecarboxylic acid + Reduced acceptor R03688 L-fuconate hydro-lyase; L-Fuconate <=> 2-Dehydro-3-deoxy-L-fuconate + H2O R03689 lanosterol delta24-reductase; Lanosterol + NADPH + H+ <=> 24,25-Dihydrolanosterol + NADP+ R03691 ATP:lombricine N-phosphotransferase; ATP + D-Lombricine <=> ADP + N-Phospho-D-lombricine R03692 dihydrocoumarin lactonohydrolase; Dihydrocoumarin + H2O <=> 3-(2-Hydroxyphenyl)propanoate R03693 (S)-2-methylmalate hydro-lyase; (S)-2-Methylmalate <=> Mesaconate + H2O R03694 Mesaconate + H2O <=> L-threo-3-Methylmalate R03695 Mesaconate + CoA <=> 2-Methylfumaryl-CoA + H2O R03696 L-threo-3-methylaspartate ammonia-lyase; L-threo-3-Methylaspartate <=> Mesaconate + Ammonia R03697 Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen R03698 oripavine,2-oxoglutarate:oxygen oxidoreductase (6-O-demethylating); Oripavine + 2-Oxoglutarate + Oxygen <=> Morphinone + Formaldehyde + Succinate + CO2 R03699 diphosphate:purine nucleoside phosphotransferase; Diphosphate + N-D-Ribosylpurine <=> Orthophosphate + Purine mononucleotide R03700 3'-phosphoadenylylsulfate:galactosylsphingosine sulfotransferase; 3'-Phosphoadenylyl sulfate + Psychosine <=> Adenosine 3',5'-bisphosphate + Psychosine sulfate R03701 S-adenosyl-L-methionine:thiopurine S-methyltransferase; S-Adenosyl-L-methionine + Thiopurine <=> S-Adenosyl-L-homocysteine + 6-Methylmercaptopurine R03702 triacetolactone lactonohydrolase; Triacetate lactone + H2O <=> Triacetate R03703 raucaffricine beta-D-glucohydrolase; Raucaffricine + H2O <=> Vomilenine + D-Glucose R03704 5,10-methylenetetrahydrofolate:tRNA-UpsiC (uracil-5-)-methyltransferase; 5,10-Methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2 <=> Tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD R03706 poly(beta-D-1,4-mannuronide) lyase; (Alginate)n <=> Oligouronide with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl group R03707 (S,S)-butane-2,3-diol:NAD+ oxidoreductase; (S,S)-Butane-2,3-diol + NAD+ <=> (S)-Acetoin + NADH + H+ R03708 1,4-lactone hydroxyacylhydrolase; gamma-Butyrolactone + H2O <=> 4-Hydroxyacid R03709 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase; 3-(2-Hydroxyphenyl)propanoate + NAD+ <=> trans-2-Hydroxycinnamate + NADH + H+ R03710 UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase; UDP-glucose + trans-2-Hydroxycinnamate <=> UDP + trans-beta-D-Glucosyl-2-hydroxycinnamate R03711 actinomycin lactonohydrolase; Actinomycin + H2O <=> Actinomycinic monolactone R03712 albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming); Albendazole + Oxygen + NADPH + H+ <=> Albendazole S-oxide + NADP+ + H2O R03713 11beta,21-dihydroxy-3,20-oxo-5beta-pregnan-18-al:NADP+ delta4-oxidoreductase; 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> Aldosterone + NADPH + H+ R03714 11beta,21-dihydroxy-3,20-oxo-5beta-pregnan-18-al:(acceptor) delta4-oxidoreductase; 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + Acceptor <=> Aldosterone + Reduced acceptor R03716 chlordecone-alcohol:NADP+ 2-oxidoreductase; Chlordecone alcohol + NADP+ <=> Chlordecone + NADPH + H+ R03718 choloyl-CoA:glycine N-choloyltransferase; Choloyl-CoA + Glycine <=> CoA + Glycocholate R03719 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase; choloyl-CoA:propanoyl-CoA C-acyltransferase; Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA R03720 choloyl-CoA:glycine N-choloyltransferase; Choloyl-CoA + Taurine <=> CoA + Taurocholate R03721 S-adenosyl-L-methionine:columbamine O-methyltransferase; S-Adenosyl-L-methionine + Columbamine <=> S-Adenosyl-L-homocysteine + Palmatine R03722 (S)-tetrahydrocolumbamine:oxigen oxidoreductase; Isocorypalmine + 2 Oxygen <=> Columbamine + 2 Hydrogen peroxide R03723 (24R,24(1)R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming); (24R,24(1)R)-Fucosterol epoxide <=> Desmosterol + Acetaldehyde R03724 Desmosterol + Acceptor <=> 7-Dehydrodesmosterol + Reduced acceptor R03725 Desmosterol + S-Adenosyl-L-methionine <=> 24-Methylenecholesterol + S-Adenosyl-L-homocysteine R03726 S-adenosyl-L-methionine:N6-(delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase; S-Adenosyl-L-methionine + N6-(Delta2-Isopentenyl)-adenine <=> 5'-Methylthioadenosine + Discadenine R03727 feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase; Feruloyl-CoA + D-Galactarate <=> CoA + O-Feruloylgalactarate R03728 octadecanal alkane-lyase; Octadecanal + Oxygen + 2 NADPH + 2 H+ <=> Heptadecane + Formate + H2O + 2 NADP+ R03731 S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase; S-Adenosyl-L-methionine + Isoorientin <=> S-Adenosyl-L-homocysteine + Isoscoparine R03732 (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD+, L-aminopentanoate-forming); (2S)-2-{[1-(R)-Carboxyethyl]amino}pentanoate + NAD+ + H2O <=> L-Norvaline + Pyruvate + NADH + H+ R03733 L-threonate:NAD+ 3-oxidoreductase; Threonate + NAD+ <=> 3-Dehydro-L-threonate + NADH + H+ R03734 3,3',5-triiodo-L-thyronine,iodide:acceptor oxidoreductase (iodinating); Thyroxine + Reduced acceptor <=> Triiodothyronine + Iodide + Acceptor + H+ R03735 (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating); (2S,3S)-2-Hydroxytridecane-1,2,3-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + Oxaloacetate R03736 rifamycin-B:oxygen oxidoreductase; Rifamycin B + Oxygen <=> Rifamycin O + Hydrogen peroxide R03737 (6S)-6beta-hydroxyhyoscyamine,2-oxoglutarate:oxygen oxidoreductase (epoxide-forming); (6S)-Hydroxyhyoscyamine + 2-Oxoglutarate + Oxygen <=> Scopolamine + Succinate + CO2 + H2O R03738 3-alpha(S)-strictosidine tryptamine-lyase; 3-alpha(S)-Strictosidine + H2O <=> Tryptamine + Secologanin R03739 stipitatonate carboxy-lyase (decyclizing); Stipitatonate + H2O <=> Stipitatate + CO2 R03740 Trichodiene <=> Nivalenol R03742 protoaphin-aglucone hydro-lyase (cyclizing); Protoaphin aglucone <=> Xanthoaphin + H2O R03743 beta-lactamhydrolase; beta-Lactam + H2O <=> Substituted beta-amino acid R03744 ATP:tau-protein O-phosphotransferase; ATP + tau-Protein <=> ADP + O-Phospho-tau-protein R03745 (+)-cis-sabinol:NAD+ oxidoreductase; (+)-cis-Sabinol + NAD+ <=> (+)-Sabinone + NADH + H+ R03746 S-adenosyl-L-methionine:2-iodophenol O-methyltransferase; S-Adenosyl-L-methionine + 2-Iodophenol <=> S-Adenosyl-L-homocysteine + 2-Iodophenol methyl ether R03747 3-oxododecanoate carboxy-lyase; 3-Oxododecanoic acid <=> 2-Undecanone + CO2 R03748 3-oxosteroid:(acceptor) delta1-oxidoreductase; 3-Oxosteroid + Acceptor <=> 3-Oxo-Delta1-steroid + Reduced acceptor R03749 (5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming); (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid R03751 epsilon-caprolactone lactonohydrolase; epsilon-Caprolactone + H2O <=> 6-Hydroxyhexanoic acid R03753 7beta-hydroxysteroid:NADP+ 7-oxidoreductase; 7beta-Hydroxysteroid + NADP+ <=> 7-Oxosteroid + NADPH + H+ R03754 ATP:acylglycerol 3-phosphotransferase; ATP + Acylglycerol <=> ADP + Acyl-sn-glycerol 3-phosphate R03755 acyl-CoA:2-acylglycerol O-acyltransferase; Acyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol R03756 2,3-dehydroacyl-CoA:2-acylglycerol O-acyltransferase; 2,3-Dehydroacyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol R03758 Aminoacetone + CO2 <=> L-2-Amino-3-oxobutanoic acid R03759 (R)-1-aminopropan-2-ol:NAD+ oxidoreductase; (R)-1-Aminopropan-2-ol + NAD+ <=> Aminoacetone + NADH + H+ R03760 acetyl-CoA:2-arylethylamine N-acetyltransferase; Acetyl-CoA + 2-Arylethylamine <=> CoA + N-Acetyl-2-arylethylamine R03761 NADH:asparagusate oxidoreductase; Asparagusate + NADH + H+ <=> 3-Sulfanyl-2-(sulfanylmethyl)propanoate + NAD+ R03762 biotin:CoA ligase (AMP-forming); biotinyl-5'-AMP:CoA biotinyltransferase; Biotinyl-5'-AMP + CoA <=> AMP + Biotinyl-CoA R03763 23,24-dihydrocucurbitacin:NAD+ delta23-oxidoreductase; 23,24-Dihydrocucurbitacin B + NAD+ <=> Cucurbitacin B + NADH + H+ R03764 23,24-dihydrocucurbitacin:NADP+ delta23-oxidoreductase; 23,24-Dihydrocucurbitacin B + NADP+ <=> Cucurbitacin B + NADPH + H+ R03765 Cycloartenol <=> Zymosterol R03766 ATP:D-hamamelose 2'-phosphotransferase; ATP + D-Hamamelose <=> ADP + D-Hamamelose 2(1)-phosphate R03767 acetyl-CoA:gentamicin-C N3-acetyltransferase; Acetyl-CoA + Gentamicin C <=> CoA + N3-Acetylgentamicin C R03768 GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase; GDP-mannose + Heteroglycan <=> GDP + 2-alpha-D-Mannosylheteroglycan R03769 GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase; GDP-mannose + Heteroglycan <=> GDP + 3-alpha-D-Mannosylheteroglycan R03770 ATP:hygromycin-B 7''-O-phosphotransferase; ATP + Hygromycin B <=> ADP + 7''-O-Phosphohygromycin R03771 L-lysyl-tRNA(Lys):phosphatidylglycerol 3-O-lysyltransferase; L-Lysyl-tRNA + Phosphatidylglycerol <=> tRNA(Lys) + 3-O-L-Lysyl-1-O-phosphatidylglycerol R03772 L-rhamno-1,4-lactone lactonohydrolase; L-Rhamnono-1,4-lactone + H2O <=> L-Rhamnonate R03774 L-rhamnonate hydro-lyase; L-Rhamnonate <=> 2-Dehydro-3-deoxy-L-rhamnonate + H2O R03775 cycloeucalenol lyase (cyclopropane-decyclizing); Cycloeucalenol <=> Obtusifoliol R03776 trans-Oct-2-enoyl-CoA reductase; Octanoyl-CoA + NADP+ <=> trans-Oct-2-enoyl-CoA + NADPH + H+ R03777 octanoyl-CoA:electron-transfer flavoprotein 2-oxidoreductase; Octanoyl-CoA + FAD <=> trans-Oct-2-enoyl-CoA + FADH2 R03778 octanoyl-CoA:acetyl-CoA C-acyltransferase; Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA R03779 octanoyl-CoA:L-carnitine O-octanoyltransferase; Octanoyl-CoA + L-Carnitine <=> CoA + L-Octanoylcarnitine R03780 ATP:macrolide 2'-O-phosphotransferase; ATP + Oleandomycin <=> ADP + Oleandomycin 2'-O-phosphate R03781 nonane-4,6-dione acylhydrolase; Nonane-4,6-dione + H2O <=> Pentan-2-one + Butanoic acid R03782 isopiperitenone delta8-delta4-isomerase; Isopiperitenone <=> Piperitenone R03783 pregnenolone,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); Pregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O R03784 pregnenolone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); Pregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 21-Hydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O R03785 ATP:taurocyamine N-phosphotransferase; ATP + Taurocyamine <=> ADP + N-Phosphotaurocyamine R03787 5,12-dihydroxanthommatin:NAD+ oxidoreductase; 5,12-Dihydroxanthommatin + NAD+ <=> Xanthommatin + NADH + H+ R03788 S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase; S-Adenosyl-L-methionine + m7G(5')pppAm-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppm6Am-mRNA R03789 tRNA-guanosine34:queuine tRNA-D-ribosyltransferase; tRNA guanine + Queuine <=> tRNA queuine + Guanine R03790 (R)-mandelate:NAD+ 2-oxidoreductase; (R)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+ R03791 mandelate racemase; (S)-Mandelate <=> (R)-Mandelate R03792 (S)-Mandelate + NAD+ <=> alpha-Oxo-benzeneacetic acid + NADH + H+ R03793 (S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase; (S)-Mandelate + Acceptor <=> alpha-Oxo-benzeneacetic acid + Reduced acceptor R03794 (S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating); (S)-Mandelate + Tetrahydropteridine + Oxygen <=> (S)-4-Hydroxymandelate + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R03796 pyruvate-oxime:acetone oximinotransferase; Pyruvate oxime + Acetone <=> Pyruvate + Acetone oxime R03797 UDPglucose:anthocyanidin 3-O-beta-D-glucosyltransferase; UDP-glucose + Anthocyanidin <=> UDP + Anthocyanidin 3-O-beta-D-glucoside R03798 Aristolochene <=> PR-toxin R03799 dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase; 2 Dimethylallyl diphosphate + Aspulvinone E <=> 2 Diphosphate + Aspulvinone H R03800 blasticidin-S aminohydrolase; Blasticidin S + H2O <=> Deaminohydroxyblasticidin S + Ammonia R03801 1,4-beta-D-glucan glucohydrolase; Cellotetraose + H2O <=> Cellotriose + D-Glucose R03802 1,4-beta-D-glucan glucohydrolase; Cellopentaose + H2O <=> Cellotetraose + D-Glucose R03803 deoxylimonate A-ring-lactonohydrolase; Deoxylimonate + H2O <=> Deoxylimononic acid D-ring-lactone R03804 monoamide of a dicarboxylic acid amidohydrolase; Monoamide of dicarboxylate + H2O <=> Dicarboxylate + Ammonia R03805 S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase; S-Adenosyl-L-methionine + G(5')pppPur-mRNA + H+ <=> S-Adenosyl-L-homocysteine + m7G(5')pppR-mRNA R03806 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A44 diacid + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2 + H2O R03807 (gibberellin-19),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A19 + 2 2-Oxoglutarate + 2 Oxygen <=> Gibberellin A20 + 3 CO2 + 2 Succinate + H2O R03809 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A20 + 2-Oxoglutarate + Oxygen <=> Gibberellin A29 + Succinate + CO2 R03810 2,5-dioxopiperazine amidohydrolase; 2,5-Dioxopiperazine + H2O <=> Glycylglycine R03812 L-hyoscyamine,2-oxoglytarate:oxygen oxidoreductase ((6S)-hydroxylating); L-Hyoscyamine + 2-Oxoglutarate + Oxygen <=> (6S)-Hydroxyhyoscyamine + Succinate + CO2 R03813 L-leucyl-tRNA(Leu):protein leucyltransferase; L-Leucyl-tRNA + Protein <=> tRNA(Leu) + L-Leucyl-protein R03814 linoleoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); Linoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> gamma-Linolenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R03815 dihydrolipoylprotein:NAD+ oxidoreductase; Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+ R03816 NADH:phylloquinone oxidoreductase; Phylloquinone + NADH + H+ <=> Phylloquinol + NAD+ R03817 plastoquinol:oxidized-plastocyanin oxidoreductase; Plastoquinol + 2 Oxidized plastocyanin + 2 H+ <=> Plastoquinone + 2 Reduced plastocyanin + 4 H+ R03818 (+)-camphor,reduced-putidaredoxin:oxygen oxidoreductase (5-hydroxylating); Reduced putidaredoxin + (+)-Camphor + Oxygen <=> (+)-exo-5-Hydroxycamphor + Oxidized putidaredoxin + H2O R03819 ATP:sedoheptulose 1-phosphotransferase; ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate R03820 strictosidine beta-D-glucohydrolase; 3-alpha(S)-Strictosidine + H2O <=> Strictosidine aglycone + D-Glucose R03821 trypanathione:NADP+ oxidoreductase; Trypanothione + NADP+ <=> Trypanothione disulfide + NADPH + H+ R03822 glutathionylspermidine:glutathione ligase (ADP-forming); ATP + Glutathionylspermidine + Glutathione <=> ADP + Orthophosphate + Trypanothione R03823 beta-Carotene <=> Lycopene R03824 carotenoid beta-end group lyase (decyclizing); gamma-Carotene <=> beta-Carotene R03826 dTDP-D-galactose:NAD+ 6-oxidoreductase; dTDP-galactose + H2O + 2 NAD+ <=> dTDP-D-galacturonate + 2 NADH + 2 H+ R03827 (2S)-flavan-4-ol:NADP+ 4-oxidoreductase; (2S)-Flavan-4-ol + NADP+ <=> (2S)-Flavanone + NADPH + H+ R03828 GTP:mRNA guanylyltransferase; GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA R03829 GDPmannose:glucomannan 1,4-beta-D-mannosyltransferase; GDP-mannose + Glucomannan <=> GDP + Glucomannan longer by one mannose unit R03830 (S)-2-haloacid halidohydrolase; (S)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide R03831 (S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming); (S)-Reticuline + Oxygen <=> (S)-Scoulerine + Hydrogen peroxide R03832 S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase; S-Adenosyl-L-methionine + 3'-Hydroxy-N-methyl-(S)-coclaurine <=> S-Adenosyl-L-homocysteine + (S)-Reticuline + H+ R03833 (S)-reticuline,[reduced NADPH---hemoprotein reductase]:oxygen 1,2-oxidoreductase; (S)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1,2-Dehydroreticuline + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R03834 (S)-scoulerine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(S)-cheilanthifoline-forming]; (S)-Scoulerine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Cheilanthifoline + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R03835 S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase; S-Adenosyl-L-methionine + (S)-Scoulerine <=> S-Adenosyl-L-homocysteine + Isocorypalmine R03836 11-cis-Retinal <=> Iodopsin R03838 acyl-CoA:2-acylglycerol O-acyltransferase; 2,3-Dehydroacyl-CoA + 2-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol R03840 ATP:5'-dephosphopolynucleotide 5'-phosphotransferase; ATP + 5'-Dephospho-DNA <=> ADP + 5'-Phospho-DNA R03841 acyl-phosphate:D-hexose phosphotransferase; Acyl phosphate + D-Hexose <=> Carboxylate + D-Hexose phosphate R03842 (S)-cis-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating); (S)-cis-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Allocryptopine + [Oxidized NADPH---hemoprotein reductase] + H2O R03845 chlorophyllide-a:NADP+ 7,8-oxidoreductase; Chlorophyllide + NADP+ <=> Protochlorophyllide + NADPH + H+ R03847 corticosterone:NAD+ 11-oxidoreductase; Corticosterone + NAD+ <=> 11-Dehydrocorticosterone + NADH + H+ R03848 corticosterone:NADP+ 11-oxidoreductase; Corticosterone + NADP+ <=> 11-Dehydrocorticosterone + NADPH + H+ R03849 11beta-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); 11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O R03850 11beta,21-dihydroxy-5beta-pregnane-3,20-dione:NADP+ 4,5-oxidoreductase; 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADP+ <=> Corticosterone + NADPH + H+ R03851 11-deoxycorticosterone,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating); 11-Deoxycorticosterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Corticosterone + 2 Oxidized ferredoxin + H2O R03852 nucleoside:purine(pyrimidine) D-ribosyltransferase; D-Ribosyl-base + Base <=> D-Ribosyl-base + Base R03854 2,2-dialkylglycine carboxylyase(amino-transferring); 2,2-Dialkylglycine + Pyruvate <=> Dialkyl ketone + CO2 + L-Alanine R03856 trans-dodec-2-enoyl-CoA reductase; Lauroyl-CoA + NADP+ <=> 2-trans-Dodecenoyl-CoA + NADPH + H+ R03857 lauroyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Lauroyl-CoA + FAD <=> 2-trans-Dodecenoyl-CoA + FADH2 R03858 lauroyl-CoA:acetyl-CoA C-acyltransferase; Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA R03859 3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating); (3S,4S)-3-Hydroxytetradecane-1,3,4-tricarboxylate + CoA <=> Lauroyl-CoA + H2O + 2-Oxoglutarate R03860 geissoschizine:NADP+ 4,21-oxidoreductase; (19E)-Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH R03861 sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase; Sinapoyl-CoA + D-Glucono-1,5-lactone <=> CoA + O-Sinapoylglucarolactone R03862 L-arginyl-tRNA(Arg):protein arginyltransferase; L-Arginyl-tRNA(Arg) + Protein <=> tRNA(Arg) + L-Arginyl-protein R03863 Leukotriene B4 + NAD+ <=> 12-Keto-leukotriene B4 + H+ + NADH R03864 Leukotriene B4 + NADP+ <=> 12-Keto-leukotriene B4 + H+ + NADPH R03866 (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating); Leukotriene B4 + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-OH-Leukotriene B4 + [Oxidized NADPH---hemoprotein reductase] + H2O R03867 (5-glutamyl)-peptide:amino-acid 5-glutamyltransferase; Leukotriene C4 + Amino acid <=> Leukotriene D4 + 5-L-Glutamyl amino acid R03868 3-maleylpyruvate cis-trans-isomerase; Maleylpyruvate <=> 3-Fumarylpyruvate R03869 (S)-methylmalonate semialdehyde:NAD+ oxidoreductase; (S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+ R03870 5-methylbarbiturate amidohydrolase; 5-Methylbarbiturate + 2 H2O <=> Methylmalonate + Urea R03871 (S)-methylmalonate semialdehyde:oxygen oxidoreductase; Methylmalonate + Hydrogen peroxide <=> (S)-Methylmalonate semialdehyde + Oxygen + H2O R03872 Methylmalonate <=> (S)-Methylmalonate semialdehyde R03873 N-acetylindoxyl:oxygen oxidoreductase; N-Acetylisatin <=> N-Acetylindoxyl + Oxygen R03874 [peptide]-(2S)-2-hydroxyglycine peptidyl-amide-lyase (glyoxylate-forming); [Peptide]-(2S)-2-hydroxyglycine <=> [Peptide]-amide + Glyoxylate R03875 Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine R03876 ATP + Ubiquitin + Protein lysine <=> AMP + Diphosphate + Protein N-ubiquityllysine R03877 magnesium-protoporphyrin IX chelatase; ATP + Protoporphyrin + Magnesium cation + H2O <=> ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ R03878 Thromboxane A2 + H2O <=> Thromboxane B2 R03879 UDP-L-rhamnose:NADP+ 4-oxidoreductase (3,5-epimerizing); UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ R03880 UDP-L-rhamnose:flavonol-3-O-D-glucoside L-rhamnosyltransferase; UDP-L-rhamnose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] R03881 UDP-glucosamine 4-epimerase; UDP-glucosamine <=> UDP-galactosamine R03882 1,2-dihydrosantonin:NAD+ 1,2-oxidoreductase; 1,2-Dihydrosantonin + NAD+ <=> alpha-Santonin + NADH + H+ R03883 1,2-dihydrosantonin:NADP+ 1,2-oxidoreductase; 1,2-Dihydrosantonin + NADP+ <=> alpha-Santonin + NADPH + H+ R03884 (E)-glutaconate CoA-transferase; Acetyl-CoA + (E)-Glutaconate <=> Acetate + Glutaconyl-1-CoA R03885 1-methyladenosine ribohydrolase; 1-Methyladenosine + H2O <=> 1-Methyladenine + D-Ribose R03886 10-hydroxydecanoate:NAD+ 10-oxidoreductase; 10-Hydroxydecanoic acid + NAD+ <=> 10-Oxodecanoate + NADH + H+ R03887 2-aminomuconate aminohydrolase; 2-Aminomuconate + H2O <=> gamma-Oxalocrotonate + Ammonia R03889 2-aminomuconate semialdehyde:NAD+ 6-oxidoreductase; 2-Aminomuconate semialdehyde + NAD+ + H2O <=> 2-Aminomuconate + H+ + NADH R03891 benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing); Benzene-1,2,4-triol + Oxygen <=> 2-Maleylacetate R03892 2-Maleylacetate <=> 3-Hydroxy-cis,cis-muconate R03893 4-carboxymethylenebut-2-en-4-olide lactonohydrolase; cis-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate R03894 (3S)-3-methyl-2-oxopentanoate carboxy-lyase; (S)-3-Methyl-2-oxopentanoic acid <=> 2-Methylbutanal + CO2 R03896 (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming); (R)-2-Methylmalate <=> 2-Methylmaleate + H2O R03897 2-Methylmaleate + H2O <=> D-threo-3-Methylmalate R03898 2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming); 2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate R03899 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming); N1-Acetylspermine + Oxygen + H2O <=> Spermidine + 3-Acetamidopropanal + Hydrogen peroxide R03900 3-nitropropanoate:NADP+ oxidoreductase; beta-Nitropropanoate + NADP+ <=> 3-Nitroacrylate + NADPH + H+ R03901 S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase; S-Alkyl-L-cysteine S-oxide <=> Alkyl sulfenate + Dehydroalanine R03903 acetyl-CoA:D-amino-acid N-acetyltransferase; Acetyl-CoA + D-Phenylalanine <=> CoA + N-Acetyl-D-phenylalanine R03904 dATP:depurinated-DNA purinetransferase; dATP + Depurinated DNA <=> Deoxyribose triphosphate + DNA adenine R03905 Glu-tRNA(Gln):L-glutamine amido-ligase (ADP-forming); Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O R03906 glycyrrhizinate glucuronosylhydrolase; Glycyrrhizinate + H2O <=> 1,2-beta-D-Glucuronosyl-D-glucuronate + Glycyrrhetinate R03907 latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating); Latia luciferin + Reduced acceptor + 2 Oxygen <=> Oxidized Latia luciferin + hn + Formate + Acceptor + CO2 + H2O R03908 2-methyleneglutarate carboxy-methylenemethylmutase; 2-Methyleneglutarate <=> Methylitaconate R03909 monocarboxylic acid amide amidohydrolase; Monocarboxylic acid amide + H2O <=> Carboxylate + Ammonia R03910 acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase; Acetyl-CoA + Alkane-alpha,omega-diamine <=> CoA + N-Acetyldiamine R03911 N-Acetylindoxyl <=> Indoxyl R03912 [peptide]-glycine,ascorbate:oxygen oxidoreductase (2-hydroxylating); [Peptide]-glycine + 2 Ascorbate + Oxygen <=> [Peptide]-(2S)-2-hydroxyglycine + 2 Monodehydroascorbate + H2O R03913 protein-dithiol:NAD+ oxidoreductase; NADH:protein-disulfide oxidoreductase; Protein dithiol + NAD+ <=> Protein disulfide + NADH + H+ R03914 protein-dithiol:NADP+ oxidoreductase; NADPH:protein-disulfide oxidoreductase; Protein dithiol + NADP+ <=> Protein disulfide + NADPH + H+ R03915 glutathione:protein-disulfide oxidoreductase; Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione R03916 (5-glutamyl)-peptide:amino-acid 5-glutamyltransferase; R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate R03917 poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase; n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate R03918 sinapyl alcohol:NADP+ oxidoreductase; Sinapyl alcohol + NADP+ <=> Sinapoyl aldehyde + NADPH + H+ R03919 donor:hydrogen-peroxide oxidoreductase; Sinapyl alcohol <=> Syringyl lignin R03920 ATP:D-fructose 6-phosphotransferase; ATP + beta-D-Fructose <=> ADP + beta-D-Fructose 6-phosphate R03921 sucrose 6-phosphate fructohydrolase; Sucrose 6-phosphate + H2O <=> D-Fructose + D-Glucose 6-phosphate R03922 S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] 2-O-methyltransferase; S-Adenosyl-L-methionine + m7G(5')pppR-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppRm-mRNA R03923 L-cysteine:tRNA sulfurtransferase; L-Cysteine + 'Activated' tRNA <=> L-Serine + tRNA containing a thionucleotide R03924 GDPmannose:phosphomannan mannosephosphotransferase; GDP-mannose + Phosphomannan <=> GMP + Phosphomannan mannosephosphate R03925 allantoin racemase; (S)-Allantoin <=> (R)(-)-Allantoin R03927 Pantothenate + 2 Reduced acceptor <=> Pantothenol + 2 Acceptor + H2O R03928 UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase; UDP-D-xylose + 1,4-beta-D-Xylan <=> UDP + 1,4-beta-D-Xylan R03929 2',3'-cyclic CMP 3'-nucleotidohydrolase; 2',3'-Cyclic CMP + H2O <=> 3'-CMP R03930 3-methyloxindole:NADP+ oxidoreductase; 3-Methyloxindole + NADP+ <=> 3-Methyleneoxindole + NADPH + H+ R03932 4-chlorobenzoate:CoA ligase; ATP + 4-Chlorobenzoate + CoA <=> AMP + Diphosphate + 4-Chlorobenzoyl-CoA R03933 20alpha,22beta-dihydroxycholesterol,ferredoxin:oxygen oxidoreductase (side-chain-cleaving); 20alpha,22beta-Dihydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 4-Methylpentanal + Pregnenolone + 2 H2O + 2 Oxidized adrenal ferredoxin R03934 S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase; S-Adenosyl-L-methionine + 6-Hydroxymellein <=> S-Adenosyl-L-homocysteine + 6-Methoxymellein R03935 beta-alanyl-L-arginine hydrolase; beta-Alanyl-L-arginine + H2O <=> beta-Alanine + Amino acid(Arg-) R03936 formylkynurenine hydrolase; L-Formylkynurenine + H2O <=> Formylanthranilate + L-Alanine R03937 Glutaconyl-1-CoA + H2O <=> 2-Hydroxyglutaryl-CoA R03938 S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase; S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine R03939 ATP:hypotaurocyamine N-phosphotransferase; ATP + Hypotaurocyamine <=> ADP + N-Phosphohypotaurocyamine R03940 10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase; L-Methionyl-tRNA + 10-Formyltetrahydrofolate <=> Tetrahydrofolate + N-Formylmethionyl-tRNA R03942 L-rhamnofuranose:NAD+ 1-oxidoreductase; L-Rhamnofuranose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+ R03943 N-Methyltyramine + S-Adenosyl-L-methionine <=> Hordenine + S-Adenosyl-L-homocysteine R03944 ATP:O-alkylglycerone phosphotransferase; ATP + O-Alkylglycerone <=> ADP + O-Alkylglycerone phosphate R03945 perillyl-alcohol:NAD+ oxidoreductase; (-)-Perillyl alcohol + NAD+ <=> Perillyl aldehyde + NADH + H+ R03946 3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + Phenolic steroid <=> Adenosine 3',5'-bisphosphate + Steroid O-sulfate R03947 S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase; Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+ R03948 S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase; S-Adenosyl-L-methionine + Precorrin 2 <=> S-Adenosyl-L-homocysteine + Precorrin 3A + H+ R03950 S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase; 2 S-Adenosyl-L-methionine + Uroporphyrin III <=> 2 S-Adenosyl-L-homocysteine + Sirohydrochlorin R03952 L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase; Triiodothyronine + 2-Oxoglutarate <=> 3,5,3'-Triiodothyropyruvate + L-Glutamate R03953 3-Iodo-L-tyrosine + 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Triiodothyronine + Dehydroalanine + 2 H2O R03954 Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate R03955 Xanthurenic acid + S-Adenosyl-L-methionine <=> 8-Methoxykynurenate + S-Adenosyl-L-homocysteine R03956 glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase; Glutathione + [Glu(-Cys)]n-Gly <=> Glycine + [Glu(-Cys)]n+1-Gly R03959 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); 2,5-Dihydro-5-oxofuran-2-acetate <=> cis,cis-Muconate R03962 2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2-oxidoreductase; 2'-Hydroxydihydrodaidzein + NADP+ <=> 2'-Hydroxydaidzein + NADPH + H+ R03963 2-butyne-1,4-diol:NAD+ 1-oxidoreductase; 2-Butyne-1,4-diol + NAD+ <=> 4-Hydroxy-2-butynal + NADH + H+ R03964 2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating); 2-Hydroxybiphenyl + Oxygen + NADH + H+ <=> Biphenyl-2,3-diol + NAD+ + H2O R03965 sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase; Sinapoyl-CoA + Hydroxymalonate <=> CoA + Sinapoyltartronate R03966 2-Hydroxymuconate <=> gamma-Oxalocrotonate R03968 2-isopropylmalate hydro-lyase; alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O R03969 3-(ADP)-2-phosphoglycerate phosphohydrolase; 3-(ADP)-2-phosphoglycerate + H2O <=> 3-(ADP)-glycerate + Orthophosphate R03970 (5-glutamyl)-peptide:amino-acid 5-glutamyltransferase; 3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O R03971 gamma-glutamyl-beta-aminopropiononitrile amidohydrolase; 3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O R03973 Hydroiodic acid + 3,5-Diiodo-L-tyrosine <=> 3-Iodo-L-tyrosine + Iodine R03974 chenodeoxycholoyl-CoA hydrolase; Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O R03975 glycochenodeoxycholate amidohydrolase; Glycochenodeoxycholate + H2O <=> Chenodeoxycholate + Glycine R03977 chenodeoxycholoyltaurine amidohydrolase; Taurochenodeoxycholate + H2O <=> Chenodeoxycholate + Taurine R03978 lithocholate:FAD oxidoreductase (7alpha-dehydroxylating); Chenodeoxycholate + FADH2 <=> Lithocholic acid + FAD + H2O R03979 Aryl dialkyl phosphate + H2O <=> Dialkyl phosphate + Phenol R03980 estrone 3-sulfate sulfohydrolase; Estrone 3-sulfate + H2O <=> Sulfate + Estrone R03981 UDP-alpha-D-galactose:glycosaminoglycan D-galactosyltransferase; UDP-alpha-D-galactose + Glycosaminoglycan <=> UDP + D-Galactosylglycosaminoglycan R03982 pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechloronating); Pentachlorophenol + Oxygen + NADPH + H+ <=> Chloranil + Cl- + NADP+ + H2O R03983 protein-glutamine:amine gamma-glutamyltransferase; Protein glutamine + Alkylamine <=> Protein N5-alkylglutamine + Ammonia R03984 pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing); Pyrimidodiazepine + Glutathione disulfide + H2O <=> 6-Pyruvoyltetrahydropterin + 2 Glutathione R03986 UDP-sugar sugarphosphohydrolase; UDP-sugar + H2O <=> UMP + alpha-D-Aldose 1-phosphate R03987 3'-phosphoadenylylsulfate:taurolithocholate sulfotransferase; 3'-Phosphoadenylyl sulfate + Taurolithocholate <=> Adenosine 3',5'-bisphosphate + Taurolithocholate sulfate R03989 trans-tetradec-2-enoyl-CoA reductase; Tetradecanoyl-CoA + NADP+ <=> trans-Tetradec-2-enoyl-CoA + NADPH + H+ R03990 tetradecanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Tetradecanoyl-CoA + FAD <=> trans-Tetradec-2-enoyl-CoA + FADH2 R03991 myristoyl-CoA:acetylCoA C-myristoyltransferase; Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA R03992 tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase; Tetradecanoyl-CoA + N-Terminal-glycyl-[protein] <=> CoA + N-Terminal-N-tetradecanoylglycyl-[protein] R03993 [pyruvate kinase] phosphate phosphohydrolase; [Pyruvate kinase] phosphate + H2O <=> [Pyruvate kinase] + Orthophosphate R03994 (E,E)-piperoyl-CoA:piperidine N-piperoyltransferase; (E,E)-Piperoyl-CoA + Piperidine <=> CoA + Piperine R03995 (R)-2-Methylmalate + CO2 <=> Parapyruvate + H2O R03996 UDPglucose:alpha-D-(1,3)-glucan 3-alpha-D-glucosyltransferase; UDP-glucose + 1,3-alpha-D-Glucan <=> UDP + 1,3-alpha-D-Glucan R03997 2,4-dichlorophenol,NADPH:oxygen oxidoreductase(6-hydroxylating); 2,4-Dichlorophenol + Oxygen + NADPH + H+ <=> 3,5-Dichlorocatechol + NADP+ + H2O R03998 anthranilyl-CoA,NADH:oxygen oxidoreductase (de-aromatizing); Anthraniloyl-CoA + Oxygen + 2 NADH + 2 H+ <=> 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NAD+ R03999 anthranilyl-CoA,NADH:oxygen oxidoreductase (de-aromatizing); Anthraniloyl-CoA + Oxygen + 2 NADPH + 2 H+ <=> 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NADP+ R04000 (E)-glutaconate CoA-transferase; Acetyl-CoA + 2-Hydroxyglutarate <=> Acetate + 2-Hydroxyglutaryl-CoA R04001 3-isopropylmalate hydro-lyase; (2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O R04002 ATP:branched-chain-fatty-acid 1-phosphotransferase; ATP + 2-Methylpropanoate <=> ADP + 2-Methylpropanoyl phosphate R04003 3-chloro-L-alanine chloride-lyase (adding thioglycolate); 3-Chloro-L-alanine + Thioglycolate <=> S-Carboxymethyl-L-cysteine + Cl- R04005 UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase; UDP-glucose + 4-Coumaryl alcohol <=> UDP + 4-Hydroxycinnamyl alcohol 4-D-glucoside R04006 4-hydroxycinnamyl alcohol 4-D-glucoside beta-D-glucosidase; 4-Hydroxycinnamyl alcohol 4-D-glucoside + H2O <=> 4-Coumaryl alcohol + D-Glucose R04007 donor:hydrogen-peroxide oxidoreductase; 4-Coumaryl alcohol <=> p-Hydroxyphenyl lignin R04009 Aldoxime + CO2 <=> 2-Oxoacid oxime R04010 benzyl-thiocyanate isomerase; Benzyl thiocyanate <=> Benzyl isothiocyanate R04011 L-glutamine:D-glutamyl-peptide 5-glutamyltransferase; L-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-L-Glutamyl-D-glutamyl-peptide R04012 D-glutamine:D-glutamyl-peptide 5-glutamyltransferase; D-Glutamine + D-Glutamyl-peptide <=> Ammonia + 5-D-Glutamyl-D-glutamyl-peptide R04013 S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-Adenosyl-L-methionine + 16-Methoxy-2,3-dihydro-3-hydroxytabersonine <=> S-Adenosyl-L-homocysteine + Desacetoxyvindoline R04014 dodecanoyl-[acyl-carrier-protein] hydrolase; Dodecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dodecanoic acid R04015 hydrogen:ferricytochrome-c3 oxidoreductase; 2 Ferricytochrome c3 + Hydrogen <=> 2 Ferrocytochrome c3 + 2 H+ R04016 Galactosylceramide + UDP-alpha-D-galactose <=> Digalactosylceramide + UDP R04017 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide R04018 acylneuraminyl hydrolase; Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O R04019 digalactosylceramide galactohydrolase; Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose R04020 indole-3-acetamide hydro-lyase; (Indol-3-yl)acetamide <=> 3-Indoleacetonitrile + H2O R04021 fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase; Palmitoyl-CoA + Mucus glycoprotein <=> CoA + O-Palmitoylglycoprotein R04022 palmitoyl-CoA:myelin-proteolipid O-palmitoyltransferase; Palmitoyl-CoA + Myelin proteolipid <=> CoA + Myelin proteolipid O-palmitoylprotein R04023 ATP:myosin-heavy-chain O-phosphotransferase; ATP + Myosin heavy chain <=> ADP + Myosin heavy-chain phosphate R04024 acetyl-CoA:N-hydroxyarylamine O-acetyltransferase; Acetyl-CoA + Hydroxylaminobenzene <=> CoA + N-(Acetyloxy)benzenamine R04025 N-acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing); N-Acetylputrescine + H2O + Oxygen <=> N4-Acetylaminobutanal + Ammonia + Hydrogen peroxide R04026 N-Formiminoglycine <=> Imidazolone + H2O R04027 N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia R04028 6-acetamido-2-oxohexanoate:2-oxoglutarata aminotransferase; 6-Acetamido-3-aminohexanoate + 2-Oxoglutarate <=> 6-Acetamido-3-oxohexanoate + L-Glutamate R04029 N6-acetyl-L-lysine:2-oxoglutarate aminotransferase; N6-Acetyl-L-lysine + 2-Oxoglutarate <=> 6-Acetamido-2-oxohexanoate + L-Glutamate R04030 O-succinylbenzoate:CoA ligase (AMP-forming); ATP + 2-Succinylbenzoate + CoA <=> AMP + Diphosphate + 2-Succinylbenzoyl-CoA R04031 (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate hydrolyase (2-succinylbenzoate-forming); 2-Succinylbenzoate + H2O <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate R04032 peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing); Peptide tryptophan + Oxygen <=> Peptide formylkynurenine R04033 S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + Phenylethanolamine <=> S-Adenosyl-L-homocysteine + N-Methylphenylethanolamine R04034 3-sn-phosphatidyl-L-serine sn-1 acylhydrolase; Phosphatidylserine + H2O <=> 2-Acyl-sn-glycero-3-phosphoserine + Fatty acid R04035 phosphoribosyl-ATP pyrophosphohydrolase; 1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate R04036 photinus-luciferin:oxygen 4-oxidoreductase(decarboxylating,ATP-hydrolysing); Photinus luciferin + Oxygen + ATP <=> Oxidized Photinus luciferin + hn + AMP + Diphosphate + CO2 R04037 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase; Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide R04038 2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase; Dimethylallyl diphosphate + AMP <=> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate R04039 [xanthine-dehydrogenase]:glutathione-disulfide S-oxidoreductase; [Xanthine dehydrogenase] + Glutathione disulfide <=> [Xanthine oxidase] + 2 Glutathione R04040 alpha-pinene-oxide lyase (ring-opening); alpha-Pinene-oxide <=> (Z)-2-Methyl-5-isopropylhexa-2,5-dienal R04043 2-acetyl-1-alkyl-sn-glycerol acetylhydrolase; 1-Alkyl-2-acetyl-sn-glycerol + H2O <=> 1-Alkyl-sn-glycerol + Acetate R04046 NADH:N-hydroxy-2-acetamidofluorene N-oxidoreductase; 2-Acetamidofluorene + NAD+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADH + H+ R04047 NADPH:N-hydroxy-2-acetamidofluorene N-oxidoreductase; 2-Acetamidofluorene + NADP+ + H2O <=> N-Hydroxy-2-acetamidofluorene + NADPH + H+ R04048 2-Dehydro-D-glucose + Oxygen <=> 2-Dehydro-D-glucono-1,5-lactone + Hydrogen peroxide R04049 2-Deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+ R04050 malonyl-CoA:3,4-dichloroaniline N-malonyltransferase; Malonyl-CoA + 3,4-Dichloroaniline <=> CoA + N-(3,4-Dichlorophenyl)-malonamate R04051 3-Phosphonopyruvate + L-Glutamate <=> 2-Amino-3-phosphonopropanoate + 2-Oxoglutarate R04053 3-phosphonopyruvate carboxy-lyase; 3-Phosphonopyruvate <=> Phosphonoacetaldehyde + CO2 R04055 triacylglycerol:3beta-hydroxysteroid O-acyltransferase; Triacylglycerol + 3beta-Hydroxysteroid <=> Diacylglycerol + 3beta-Hydroxysteroid ester R04056 4-acetamidobutyryl-CoA amidohydrolase; 4-Acetamidobutanoyl-CoA + H2O <=> Acetate + 4-Aminobutanoyl-CoA R04057 acetyl-CoA:5-hydroxypentanoate CoA-transferase; Acetyl-CoA + 5-Hydroxypentanoate <=> Acetate + 5-Hydroxypentanoyl-CoA R04058 L-glutaminyl-peptide gamma-gluramyltransferase (cyclizing); L-Glutaminyl-peptide <=> 5-Oxoprolyl-peptide + Ammonia R04059 (+/-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase; (+/-)-trans-Acenaphthene-1,2-diol + 2 NADP+ <=> Acenaphthenequinone + 2 NADPH + 2 H+ R04060 anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating); Anhydrotetracycline + Oxygen + NADPH + H+ <=> 5a,11a-Dehydrotetracycline + NADP+ + H2O R04061 benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing); Benzene-1,2,4-triol + Oxygen <=> 3-Hydroxy-cis,cis-muconate R04062 S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase; S-Adenosyl-L-methionine + Calmodulin L-lysine <=> S-Adenosyl-L-homocysteine + Calmodulin N6-methyl-L-lysine R04063 cypridina-luciferin:oxygen 2-oxidoreductase(decarboxylating); Cypridina luciferin + Oxygen <=> Oxidized Cypridina luciferin + hn + CO2 R04065 imidazole acetaldehyde:NAD+ oxidoreductase; Imidazole-4-acetaldehyde + NAD+ + H2O <=> Imidazole-4-acetate + NADH + H+ R04066 imidazole-4-acetate,NADH:oxygen oxidoreductase (5-hydroxylating); Imidazole-4-acetate + Oxygen + NADH + H+ <=> 4-Imidazolone-5-acetate + NAD+ + H2O R04068 imidazole-4-acetate:5-phosphoribosyl-diphosphate ligase (ADP- and pyrophosphate- forming); ATP + Imidazole-4-acetate + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O <=> ADP + Orthophosphate + 1-(5-Phosphoribosyl)imidazole-4-acetate + Diphosphate R04070 N5-acyl-L-ornithine-ester hydrolase; N5-Acyl-L-ornithine ester + H2O <=> N5-Acyl-L-ornithine + Alcohol R04071 UDPglucose:zeatin 7-glucosyltransferase; UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-7-beta-D-glucoside R04072 dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase; Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein] R04073 peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Peptide L-aspartate + 2-Oxoglutarate + Oxygen <=> Peptide 3-hydroxy-L-aspartate + Succinate + CO2 R04074 NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase; NAD+ + Peptide diphthamide <=> Nicotinamide + Peptide N-(ADP-D-ribosyl)diphthamide R04076 protein-N(pi)-phosphohistidine:L-sorbose 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + L-Sorbose <=> Protein histidine + Sorbose 1-phosphate R04077 S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase; S-Adenosyl-L-methionine + Isocorypalmine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine R04078 watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating); Watasenia luciferin + Oxygen <=> Oxidized Watasenia luciferin + hn + CO2 R04080 beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing); beta-Cyclopiazonate + Acceptor <=> Cyclopiazonic acid + Reduced acceptor R04081 GDP-L-fucose:beta-D-galactosyl-R 2-fucosyltransferase; GDP-L-fucose + beta-D-Galactosyl-R <=> GDP + alpha-L-Fucosyl-1,2-beta-D-galactoside R04082 GDP-alpha-D-mannose:queuosine in tRNA(Asp) O-4''-alpha-D-mannosyltransferase (configuration-retaining); GDP-mannose + Queuosine in tRNA(Asp) <=> GDP + O-4''-alpha-D-Mannosylqueuosine in tRNA(Asp) R04084 3,4-dihydroxyphenylacetaldehyde hydro-lyase (adding dopamine); 3,4-Dihydroxyphenylacetaldehyde + Dopamine <=> (S)-Norlaudanosoline + H2O R04085 aldehyde:oxygen oxidoreductase; 1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-4-pyridone-5-carboxamide + Hydrogen peroxide + H+ R04088 toluene-cis-1,2-dihydrodiol:NAD+ oxidoreductase; Toluene-cis-dihydrodiol + NAD+ <=> 2,3-Dihydroxytoluene + NADH + H+ R04089 3-methylcatechol:oxygen 2,3-oxidoreductase(decyclizing); 2,3-Dihydroxytoluene + Oxygen <=> 2-Hydroxy-6-keto-2,4-heptadienoate R04090 S-(2-hydroxyacyl)glutathione hydrolase; S-(2-Hydroxyacyl)glutathione + H2O <=> Glutathione + 2-Hydroxy carboxylate R04091 O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl); O-Acetyl-L-serine + 3,4-Dihydroxypyridine + H+ <=> 3-(3,4-Dihydroxypyridin-1-yl)-L-alanine + Acetate R04092 3-Dehydrosphinganine + FAD <=> 3-Ketosphingosine + FADH2 R04093 3-indoleacetaldoxime hydro-lyase; Indole-3-acetaldehyde oxime <=> 3-Indoleacetonitrile + H2O R04094 thioglucoside glucohydrolase; Glucobrassicin + H2O <=> 3-Indoleacetonitrile + D-Glucose + Sulfate + Sulfur R04095 3-methylbutanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; 3-Methylbutanoyl-CoA + FAD <=> 3-Methylcrotonyl-CoA + FADH2 R04096 3-methylbutanoyl-CoA:(acceptor) oxidoreductase; 3-Methylbutanoyl-CoA + Electron-transferring flavoprotein <=> 3-Methylcrotonyl-CoA + Reduced electron-transferring flavoprotein R04097 3-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(3-methylbutanoyl)transferase; 3-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine R04098 3-Methylbutanoyl-CoA <=> Branched chain fatty acid R04099 3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase; 3alpha-Hydroxyglycyrrhetinate + NADP+ <=> 3-Oxoglycyrrhetinate + NADPH + H+ R04100 3-cis-dodecenoyl-CoA delta3-cis-delta2-trans-isomerase; 3-cis-Dodecenoyl-CoA <=> 2-trans-Dodecenoyl-CoA R04101 4-chlorobenzoyl CoA chlorohydrolase; 4-Chlorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Cl- + H+ R04102 (+)-bornane-2,5-dione,FMNH2:oxygen oxidoreductase (1,2-lactonizing); (+)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> 5-Oxo-1,2-campholide + FMN + H2O R04103 penicillin amidohydrolase; Penicillin G + H2O <=> 6-Aminopenicillanate + Phenylacetic acid R04104 chondroitin-D-glucuronate 5-epimerase; Chondroitin <=> Dermatan R04105 ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase; Ethyl (R)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+ R04106 ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase; Ethyl (S)-3-hydroxyhexanoate + NADP+ <=> Ethyl 3-oxohexanoate + NADPH + H+ R04108 UDPglucose:hydroxyanthraquinone O-glucosyltransferase; UDP-glucose + Hydroxyanthraquinone <=> UDP + Glucosyloxyanthraquinone R04109 L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNA(Glu)-forming); L-Glutamyl-tRNA(Glu) + NADPH + H+ <=> (S)-4-Amino-5-oxopentanoate + tRNA(Glu) + NADP+ R04111 protein-N(pi)-phosphohistidine:maltose 6'-phosphotransferase; Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate R04112 N-acetylmuramoyl-Ala amidohydrolase; N-Acetylmuramoyl-Ala + H2O <=> N-Acetylmuramate + L-Alanine R04113 N-benzoyl-D-arginine-4-nitroanilide amidohydrolase; N-Benzoyl-D-arginine-4-nitroanilide + H2O <=> N-Benzoyl-D-arginine + 4-Nitroaniline R04115 cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase; cis-1,2-Dihydronaphthalene-1,2-diol + NAD+ <=> Naphthalene-1,2-diol + NADH + H+ R04117 naphthalene-1,2-diol:oxygen oxidoreductase; Naphthalene-1,2-diol + Oxygen <=> 2-Hydroxychromene-2-carboxylate R04118 oligoglycosylglucosylceramide glycohydrolase; Oligoglycosylglucosylceramide + H2O <=> Oligoglycosylglucose + N-Acylsphingosine R04119 12,13-diacylphorbate 12-acylhydrolase; Phorbol 12,13-dibutanoate + H2O <=> Phorbol 13-butanoate + Butanoic acid R04120 peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming]; Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (S)-S-oxide + Thioredoxin R04121 fatty acid,reduced-flaboprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); [Reduced NADPH---hemoprotein reductase] + Fatty acid + Oxygen <=> alpha-Hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O R04122 alkane,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating); [Reduced NADPH---hemoprotein reductase] + Alkane + Oxygen <=> [Oxidized NADPH---hemoprotein reductase] + ROH + H2O R04123 transferrin[Fe(II)]2:NAD+ oxidoreductase; Transferrin[Fe(II)]2 + NAD+ + H+ <=> Transferrin[Fe(III)]2 + NADH R04124 Transferrin[Fe(II)]2 <=> Apotransferrin + 2 Fe2+ R04125 [protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming); [Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia R04126 ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase; ATP + 1-Alkyl-sn-glycerol <=> ADP + 1-Alkyl-sn-glycero-3-phosphate R04127 UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase; UDP-glucose + 13-Hydroxydocosanoic acid <=> UDP + 13-beta-D-Glucosyloxydocosanoate R04130 2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating); 2,6-Dihydroxypyridine + Oxygen + NADH + H+ <=> 2,3,6-Trihydroxypyridine + NAD+ + H2O R04131 2-Oxohept-3-enedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate R04132 2-Oxohept-3-enedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate R04133 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase; 5-Carboxy-2-oxohept-3-enedioate <=> 2-Oxohept-3-enedioate + CO2 R04134 2-Oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate R04135 3-hydroxy-L-glutamate 1-carboxy-lyase; 3-Hydroxy-L-glutamate <=> 4-Amino-3-hydroxybutanoate + CO2 R04136 3-hydroxybenzyl-alcohol:NADP+ oxidoreductase; 3-Hydroxybenzyl alcohol + NADP+ <=> 3-Hydroxybenzaldehyde + NADPH + H+ R04137 3-hydroxyisovaleryl-CoA hydro-lyase; 3-Hydroxyisovaleryl-CoA <=> 3-Methylcrotonyl-CoA + H2O R04138 3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + 3-Methylcrotonyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-Methylglutaconyl-CoA R04139 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase; Lithocholic acid + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+ R04140 4-chlorophenylacetonitrile aminohydrolase; 4-Chlorophenylacetonitrile + 2 H2O <=> 4-Chlorophenylacetate + Ammonia R04141 4-methylumbelliferyl-acetate acylhydrolase; 4-Methylumbelliferyl acetate + H2O <=> 4-Methylumbelliferone + Acetate R04142 5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O R04143 ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase; ATP + 5-Methylthio-D-ribose <=> ADP + S-Methyl-5-thio-D-ribose 1-phosphate R04144 5-phospho-D-ribosylamine:glycine ligase (ADP-forming); ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5'-Phosphoribosylglycinamide R04145 S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase; S-Adenosyl-L-methionine + Cytochrome c L-lysine <=> S-Adenosyl-L-homocysteine + Cytochrome c N6-methyl-L-lysine R04146 N-acetyl-D-galactosaminoglycan acetylhydrolase; N-Acetyl-D-galactosaminoglycan + H2O <=> D-Galactosaminoglycan + Acetate R04147 Isopenicillin N <=> Penicillin N R04148 nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase; Nicotinate D-ribonucleotide + Dimethylbenzimidazole <=> Nicotinate + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H+ R04149 glycoprotein-phosphatidylinositol phosphatidohydrolase; Glycoprotein phosphatidylinositol + H2O <=> Phosphatidate + Glycoprotein inositol R04150 O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase; 2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoate + CoA R04151 (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase; (+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+ <=> Phenanthrene-3,4-diol + NADH + H+ R04152 (2-aminoethyl)phosphonate:pyruvate aminotransferase; 2-Aminoethylphosphonate + Pyruvate <=> Phosphonoacetaldehyde + L-Alanine R04153 dimethylsulfonioacetate:L-homocysteine S-methyltransferase; Dimethylsulfonioacetate + L-Homocysteine <=> S-Methylthioglycolate + L-Methionine + H+ R04154 tetrahydroxypteridine lyase (isomerizing); Tetrahydroxypteridine <=> Xanthine-8-carboxylate R04155 Transferrin[Fe(III)]2 <=> Apotransferrin + 2 Fe3+ R04156 [glycogen-synthase D] phosphohydrolase; [Glycogen-synthase D] + H2O <=> [Glycogen-synthase I] + Orthophosphate R04157 alpha(omega)-dicarboxylic acid:CoA ligase (AMP-forming); ATP + alpha,omega-Dicarboxylic acid + CoA <=> AMP + Diphosphate + omega-Carboxyacyl-CoA R04158 geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase; Geranylgeranyl diphosphate + sn-Glycerol 1-phosphate <=> Diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate R04159 (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase; (5-L-Glutamyl)-peptide + Amino acid <=> Peptide + 5-L-Glutamyl amino acid R04160 (S)-4-Hydroxymandelate + Acceptor <=> 4-Hydroxyphenylglyoxylate + Reduced acceptor R04161 (S)-4-hydroxymandelate racemase; (S)-4-Hydroxymandelate <=> (R)-4-Hydroxymandelate R04162 1-alkyl-2-acyl-sn-glycero-3-phosphate phosphohydrolase; 2-Acyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acylglycerol + Orthophosphate R04163 21-hydroxypregnenolone:NAD+ 3-oxidoreductase; 21-Hydroxypregnenolone + NAD+ <=> 11-Deoxycorticosterone + NADH + H+ R04165 11-deoxycorticosterone ketol-isomerase; 11-Deoxycorticosterone <=> 20-Hydroxy-3-oxopregn-4-en-21-al R04166 16alpha-hydroxyprogesterone hydro-lyase; 16alpha-Hydroxyprogesterone <=> 16-Dehydroprogesterone + H2O R04167 2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase; 2-Carboxy-D-arabinitol 1-phosphate + H2O <=> 2-Carboxy-D-arabinitol + Orthophosphate R04168 nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase; Deoxynucleoside + Base <=> Deoxynucleoside + Base R04169 S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase; S-Adenosyl-L-methionine + (E)-2-Methylpropanal oxime <=> S-Adenosyl-L-homocysteine + 2-Methylpropanal O-methyloxime R04170 (S)-3-hydroxydodecanoyl-CoA hydro-lyase; (S)-3-Hydroxydodecanoyl-CoA <=> 2-trans-Dodecenoyl-CoA + H2O R04171 3-hydroxy-L-kynurenine:2-oxoglutarate aminotransferase; 3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate R04172 3-Hydroxy-L-kynurenine <=> 3-Hydroxykynurenamine + CO2 R04173 3-phosphoserine:2-oxoglutarate aminotransferase; O-Phospho-L-serine + 2-Oxoglutarate <=> 3-Phosphonooxypyruvate + L-Glutamate R04174 6-acetamido-2-oxohexanoate amidohydrolase; 6-Acetamido-2-oxohexanoate + H2O <=> Acetate + 6-Amino-2-oxohexanoate R04175 6-Amino-2-oxohexanoate <=> Delta1-Piperideine-2-carboxylate + H2O R04176 NAD+:poly(adenosine diphosphate D-ribose)ADP-D-ribosyltransferase; NAD+ + ADP-D-ribosyl-acceptor <=> Nicotinamide + ADP-D-ribosyl-acceptor + H+ R04177 2-hydroxyethylenedicarboxylate hydro-lyase; 2-Hydroxyethylenedicarboxylate <=> Acetylenedicarboxylate + H2O R04178 coproporphyrinogen-III:oxygen oxidoreductase (coproporphyrin-forming); Coproporphyrinogen III + 3 Oxygen <=> Coproporphyrin III + 3 Hydrogen peroxide R04179 UDPglucose:glycoprotein-D-mannose glucosephosphotransferase; UDP-glucose + D-Mannosylglycoprotein <=> UMP + 6-(D-Glucose-1-phospho)-D-mannosylglycoprotein R04180 6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase; 6-(D-Glucose-1-phospho)-D-mannosylglycoprotein + H2O <=> D-Glucose 1-phosphate + D-Mannosylglycoprotein R04182 UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + N-Acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide R04183 alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase; Globoside + N-Acetyl-D-galactosamine <=> N-Acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide + H2O R04184 globoside N-acetylhexosaminohydrolase; alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-Acetyl-D-galactosamine <=> Globoside + H2O R04185 (S)-3-(imidazol-5-yl)lactate:NAD+ oxidoreductase; (S)-3-(Imidazol-5-yl)lactate + NAD+ <=> Imidazol-5-yl-pyruvate + NADH + H+ R04186 (S)-3-(imidazol-5-yl)lactate:NADP+ oxidoreductase; (S)-3-(Imidazol-5-yl)lactate + NADP+ <=> Imidazol-5-yl-pyruvate + NADPH + H+ R04187 L-alanine:3-oxopropanoate aminotransferase; L-Alanine + (S)-Methylmalonate semialdehyde <=> Pyruvate + L-3-Aminoisobutanoate R04188 L-3-amino-isobutanoate:2-oxoglutarate aminotransferase; L-3-Aminoisobutanoate + 2-Oxoglutarate <=> (S)-Methylmalonate semialdehyde + L-Glutamate R04189 N2-succinyl-L-arginine iminohydrolase (decarboxylating); N2-Succinyl-L-arginine + 2 H2O <=> N2-Succinyl-L-ornithine + CO2 + 2 Ammonia R04190 S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase; S-Adenosyl-L-methionine + Protein L-isoaspartate <=> S-Adenosyl-L-homocysteine + Protein L-isoaspartate methyl ester R04191 alpha-amino-acid-ester aminoacylhydrolase; alpha-Amino acid ester + H2O <=> alpha-Amino acid + Alcohol R04192 acetyl-CoA:alpha-tubulin-L-lysine N(epsilon)-acetyltransferase; Acetyl-CoA + [alpha-Tubulin]-L-lysine <=> CoA + [alpha-Tubulin]-N6-acetyl-L-lysine R04193 1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase; (2,1-beta-D-Fructosyl)n(m) + (2,1-beta-D-Fructosyl)n(n) <=> (2,1-beta-D-Fructosyl)n(m-1) + (2,1-beta-D-Fructosyl)n(n+1) R04194 sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase; Sucrose + (2,1-beta-D-Fructosyl)n <=> D-Glucose + (2,1-beta-D-Fructosyl)n R04198 2,3,4,5-tetrahydrodipicolinate:NAD+ 4-oxidoreductase; 2,3,4,5-Tetrahydrodipicolinate + NAD+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+ R04199 2,3,4,5-tetrahydrodipicolinate:NADP+ 4-oxidoreductase; 2,3,4,5-Tetrahydrodipicolinate + NADP+ + H2O <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ R04200 D-threo-2,4-diaminopentanoate:NAD+ oxidoreductase (deaminating); (2R,4S)-2,4-Diaminopentanoate + H2O + NAD+ <=> 2-Amino-4-oxopentanoic acid + Ammonia + NADH + H+ R04201 D-threo-2,4-diaminopentanoate:NADP+ oxidoreductase(deaminating); (2R,4S)-2,4-Diaminopentanoate + NADP+ + H2O <=> 2-Amino-4-oxopentanoic acid + NADPH + Ammonia + H+ R04202 bis(2-ethylhexyl)phthalate acylhydrolase; Bis(2-ethylhexyl)phthalate + H2O <=> Mono-(2-ethylhexyl)phthalate + 2-Ethylhexan-1-ol R04203 (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase; (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA + NAD+ <=> 2-Methylacetoacetyl-CoA + NADH + H+ R04204 (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA hydro-liase; (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <=> 2-Methylbut-2-enoyl-CoA + H2O R04205 (E)-2-methylcrotonoyl-CoA :13-hydroxylupinine O-2-methylcrotonoyltransferase; 2-Methylbut-2-enoyl-CoA + 13-Hydroxylupanine <=> CoA + 13-(2-Methylcrotonoyl)oxylupanine R04206 3-phospho-D-erythronate hydro-lyase; 3-Phospho-D-erythronate <=> Phosphoenol-4-deoxy-3-tetrulosonate + H2O R04208 2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming); ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <=> ADP + Orthophosphate + Aminoimidazole ribotide R04209 1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase; 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2 R04210 4-phospho-D-erythronate:NAD+ 2-oxidoreductase; 4-Phospho-D-erythronate + NAD+ <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ R04211 oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase; Oxalyl-CoA + L-2,3-Diaminopropanoate <=> CoA + 3-(Carboxycarbonylamino)-L-alanine R04212 Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming); L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O R04213 3'-phosphoadenylylsulfate:L-tyrosine-methyl-ester sulfotransferase; 3'-Phosphoadenylyl sulfate + L-Tyrosine methyl ester <=> Adenosine 3',5'-bisphosphate + L-Tyrosine methyl ester 4-sulfate R04214 N-Formimino-L-aspartate <=> 4-Imidazolone-5-acetate + H2O R04215 CTP:N-glycoloylneuraminate cytidylyltransferase; CTP + N-Glycoloyl-neuraminate <=> Diphosphate + CMP-N-glycoloylneuraminate R04216 dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase; Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine R04217 N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase; N2-Succinyl-L-ornithine + 2-Oxoglutarate <=> N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate R04218 prephytoene diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase; Prephytoene diphosphate <=> Diphosphate + 15-cis-Phytoene R04221 cis-4-hydroxy-D-proline:oxygen oxidoreductase (deaminating); cis-4-Hydroxy-D-proline + Oxygen <=> 1-Pyrroline-4-hydroxy-2-carboxylate + Hydrogen peroxide R04222 dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase; dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate R04223 gamma-Oxalocrotonate + H2O <=> 4-Hydroxy-2-oxopentanoate + CO2 R04224 (S)-3-hydroxyisobutyryl-CoA hydro-lyase; 2-Methylprop-2-enoyl-CoA + H2O <=> (S)-3-Hydroxyisobutyryl-CoA R04225 (S)-3-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating); (S)-3-Methyl-2-oxopentanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2 R04227 3-sn-phosphatidylcholine:dolichol O-acyltransferase; Phosphatidylcholine + Dolichol <=> Acyldolichol + 1-Acyl-sn-glycero-3-phosphocholine R04228 NADH:4-nitroquinoline-N-oxide oxidoreductase; 4-Nitroquinoline N-oxide + 2 NADH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NAD+ + H2O R04229 NADPH:4-nitroquinoline-N-oxide oxidoreductase; 4-Nitroquinoline N-oxide + 2 NADPH + 2 H+ <=> 4-Hydroxyaminoquinoline N-oxide + 2 NADP+ + H2O R04230 (R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing); ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine R04231 (R)-4'-phosphopantothenate:L-cysteine ligase; CTP + D-4'-Phosphopantothenate + L-Cysteine <=> CMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine R04234 D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase; D-4-Hydroxyphenylglycine + 2-Oxoglutarate <=> 4-Hydroxyphenylglyoxylate + L-Glutamate R04235 ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase; ATP + Deoxy-5-methylcytidylate <=> ADP + 5-Methyldeoxycytidine diphosphate R04236 propane-1,2-diol-1-phosphate:NAD+ oxidoreductase; Propane-1,2-diol 1-phosphate + NAD+ <=> Hydroxyacetone phosphate + NADH + H+ R04237 S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase; S-Adenosyl-L-methionine + Magnesium protoporphyrin <=> S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester R04238 aminoacyl-tRNA aminoacylhydrolase; N-Substituted aminoacyl-tRNA + H2O <=> N-Substituted amino acid + tRNA R04239 protein-L-lysine:oxygen 6-oxidoreductase (deaminating); Protein lysine + H2O + Oxygen <=> [Protein]-(S)-2-amino-6-oxohexanoate + Ammonia + Hydrogen peroxide R04241 tetrahydropteroyl-gamma-polyglutamate:L-glutamate gamma-ligase (ADP-forming); ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1) R04242 tetrahydropteroyl-poly-gamma-glutamate gamma-glutamylhydrolase; THF-polyglutamate + (n-1) H2O <=> Tetrahydrofolate + (n-1) L-Glutamate R04247 CTP:ethanolamine-phosphate cytidylyltransferase; CTP + 2-Aminoethylphosphonate <=> Diphosphate + CMP-2-aminoethylphosphonate R04248 2-Aminoethylphosphonate + Hydrogen peroxide <=> Ethanolamine + Orthophosphate R04249 2-Aminoethylphosphonate <=> (2-Amino-1-hydroxyethyl)phosphonate R04250 2-Aminoethylphosphonate <=> N-Monomethyl-2-aminoethylphosphonate R04251 phosphonoacetaldehyde:NAD+ oxidoreductase; Phosphonoacetaldehyde + NAD+ + H2O <=> Phosphonoacetate + NADH + H+ R04252 2-Aminoethylphosphonate <=> Ciliatocholate R04254 n (R)-3-Hydroxybutanoyl-CoA <=> Poly-beta-hydroxybutyrate + n CoA R04256 (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating); Leukotriene E4 + Oxygen + NADPH + H+ <=> 20-Hydroxyleukotriene E4 + NADP+ + H2O R04257 Resveratrol <=> Piceatannol R04258 4-Chlorocatechol + Oxygen <=> 3-Chloro-cis,cis-muconate R04259 (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening); 2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> 3-Chloro-cis,cis-muconate R04260 5-oxo-2,5-dihydrofuran-2-acetate delta3-delat2-isomerase; 2,5-Dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate R04263 7alpha-hydroxycholesterol:NAD+ 3-oxidoreductase; 7alpha-Hydroxycholesterol + NAD+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADH + H+ R04264 cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase; 7alpha-Hydroxycholesterol + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+ R04265 CDP-alpha-D-paratose:NADP+ 4-oxidoreductase; CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+ R04266 CDP-3,6-dideoxy-D-glucose 2-epimerase; CDP-3,6-dideoxy-D-glucose <=> CDP-3,6-dideoxy-D-mannose R04267 ATP:deoxynucleoside-phosphate phosphotransferase; ATP + Deoxynucleoside 5'-phosphate <=> ADP + 2'-Deoxyribonucleoside diphosphate R04268 N-formyl-L-methionylaminoacyl-tRNA amidohydrolase; N-Formyl-L-methionylaminoacyl-tRNA + H2O <=> Formate + L-Methionylaminoacyl-tRNA R04269 L-threo-3-Methylaspartate + 2-Oxoglutarate <=> Methyloxaloacetate + L-Glutamate R04270 2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase; Methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O <=> L-Fucose + Methyl beta-D-galactoside R04271 N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase; N-Hydroxy-4-acetylaminobiphenyl + N-Hydroxy-4-aminobiphenyl <=> N-Hydroxy-4-aminobiphenyl + N-Acetoxy-4-aminobiphenyl R04272 oligosaccharide-diphosphodolichol phosphodolichohydrolase; Dolichyl diphosphooligosaccharide + H2O <=> Oligosaccharide phosphate + Dolichyl phosphate R04273 peptidylproline cis-trans-isomerase; Peptidylproline (omega=180) <=> Peptidylproline (omega=0) R04274 RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming); ATP + RNA 3'-terminal-phosphate <=> AMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate R04275 ATP:[L-tyrosine,tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating)] O-phosphotransferase; ATP + [Tyrosine-3-monoxygenase] <=> ADP + Phospho-[tyrosine-3-monoxygenase] R04276 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Pelargonidin + Succinate + CO2 + 2 H2O R04277 2-pyrone-4,6-dicarboxylate lactonohydrolase; 2-Pyrone-4,6-dicarboxylate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate R04278 2-hydroxy-2-hydropyrone-4,6-dicarboxylate:NAD+ 6-oxidoreductase; 2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NAD+ <=> 2-Pyrone-4,6-dicarboxylate + NADH + H+ R04279 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal:NADP+ 2-oxidoreductase; 2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NADP+ <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+ R04280 3-O-methylgallate:oxygen 4,5-oxidoreductase (decyclizing); 3-O-Methylgallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + Methanol R04281 carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase; Carbamoyl phosphate + 3-Hydroxymethyl ceph-3-em-4-carboxylate <=> Orthophosphate + 3-Carbamoyloxymethylcephem R04282 4-Imidazolone-5-propanoate + H2O <=> Formylisoglutamine R04283 4-Imidazolone-5-propanoate + H2O <=> 4-Oxoglutaramate + Formate + Ammonia R04285 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase; 6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+ R04286 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase; 7,8-Dihydroneopterin 3'-triphosphate <=> 6-Pyruvoyltetrahydropterin + Triphosphate R04289 CMP-N-glycoloylneuraminate <=> Glycolipid R04291 UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + Lysosomal-enzyme D-mannose <=> UMP + Lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose R04292 glycerone phosphate:iminosuccinate alkyltransferase (cyclizing); Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate R04293 Quinolinate + H2O <=> 2-Amino-3-carboxymuconate semialdehyde R04294 2'-deoxyribonucleoside diphosphate:oxidized-thioredoxin 2'-oxidoreductase; 2'-Deoxyribonucleoside diphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside diphosphate + Thioredoxin R04296 UDPglucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase; UDP-glucose + (S)-4-Hydroxymandelonitrile <=> UDP + Dhurrin R04297 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase; 1,2,3,5-Tetrahydroxybenzene + 1,2,3-Trihydroxybenzene <=> 1,2,3,5-Tetrahydroxybenzene + Phloroglucinol R04299 2-Amino-2-deoxy-D-gluconate <=> Aminosugar R04300 4-(2-aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing); Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide R04301 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + Dopamine <=> S-Adenosyl-L-homocysteine + 3-Methoxytyramine R04303 NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase; para-(Dimethylamino)azobenzene + NADP+ + H2O <=> 4-(Dimethylamino)phenylazoxybenzene + NADPH + H+ R04304 4-hydroxyphenylethanol:NAD+ oxidoreductase; 4-Hydroxyphenylethanol + NAD+ <=> 4-Hydroxyphenylacetaldehyde + NADH + H+ R04305 4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine); 4-Hydroxyphenylacetaldehyde + Dopamine <=> (S)-Norcoclaurine + H2O R04306 (Z)-4-Hydroxyphenylacetaldehyde oxime <=> 4-Hydroxyphenylacetonitrile + H2O R04307 trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase; trans-4-Hydroxycyclohexanecarboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+ R04309 3alpha-hydroxy-5beta-androstan-17-one:NAD+ oxidoreductase (B-specific); Etiocholanolone + NAD+ <=> 5beta-Androstane-3,17-dione + NADH + H+ R04310 3alpha-hydroxy-5beta-androstan-17-one:NADP+ oxidoreductase (B-specific); Etiocholanolone + NADP+ <=> 5beta-Androstane-3,17-dione + NADPH + H+ R04311 1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase; Acylglycerone phosphate + Long-chain alcohol <=> O-Alkylglycerone phosphate + Long-chain acid anion R04312 pyrophosphate:microsomal-membrane-protein O-phosphotransferase; Diphosphate + Microsomal-membrane protein <=> Orthophosphate + O-Phospho-microsomal-membrane protein R04313 N6,N6,N6-Trimethyl-L-lysine + 2 Protein <=> Protein N6,N6,N6-trimethyl-L-lysine + 2 H2O R04314 DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase; DNA containing 6-O-methylguanine + [Protein]-L-cysteine <=> Protein S-methyl-L-cysteine + DNA containing guanine R04315 2'-deoxyribonucleoside triphosphate:oxydized-thioredoxin 2'-oxidoreductase; Deoxynucleoside triphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside triphosphate + Thioredoxin R04316 acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase; Acetyl-CoA + Ribosomal-protein L-alanine <=> CoA + Ribosomal-protein N-acetyl-L-alanine R04317 S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase; S-Methyl-3-phospho-1-thio-D-glycerate + H2O <=> S-Methyl-1-thio-D-glycerate + Orthophosphate R04318 penicillin-G hydrolase; Penicillin G + H2O <=> Benzylpenicilloic acid R04319 trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase; trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+ R04320 poly(1,4-alpha-D-galacturonide) galacturonohydrolase; Pectate + H2O <=> Pectate + D-Galacturonate R04321 CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase; CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine R04322 UDP-alpha-D-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyltransferase; UDP-alpha-D-galactose + 2-(2-Hydroxyacyl)sphingosine <=> UDP + 1-(beta-D-Galactosyl)-2-(2-hydroxyacyl)sphingosine R04323 2-amino-3-carboxymuconate semialdehyde carboxy-lyase; 2-Amino-3-carboxymuconate semialdehyde <=> 2-Aminomuconate semialdehyde + CO2 R04325 10-formyltetrahydrofolate:5'-phosphoribosylglycinamide formyltransferase; 10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <=> Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide R04326 5'-Phosphoribosylglycinamide + 5,10-Methenyltetrahydrofolate + H2O <=> 5'-Phosphoribosyl-N-formylglycinamide + Tetrahydrofolate R04327 5-hydroxy-1,4-naphthoquinone,water:oxygen oxidoreductase (3-hydroxylating); 2 Juglone + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone R04328 Lathosterol + CO2 + 4 H2O + 3 NADP+ <=> Methostenol + 3 Oxygen + 3 NADPH + 3 H+ R04330 androstan-3alpha,17beta-diol:NAD+ oxidoreductase; Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+ R04331 GDPmannose:chitobiosyldiphosphodolichol alpha-D-mannosyltransferase; GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosylchitobiosyldiphosphodolichol R04332 S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase; S-Adenosyl-L-methionine + Glucuronoxylan D-glucuronate <=> S-Adenosyl-L-homocysteine + Glucuronoxylan 4-O-methyl-D-glucuronate R04333 indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase; Indole-3-acetyl-beta-1-D-glucoside + myo-Inositol <=> D-Glucose + Indole-3-acetyl-myo-inositol R04334 UDP-alpha-D-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase; UDP-alpha-D-galactose + Indole-3-acetyl-myo-inositol <=> UDP + 5-O-(Indol-3-ylacetyl-myo-inositol) D-galactoside R04335 UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase; UDP-L-arabinose + Indole-3-acetyl-myo-inositol <=> UDP + Indol-3-ylacetyl-myo-inositol L-arabinoside R04336 L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O R04338 S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase; S-(4-Bromophenyl)-L-cysteine + 2-Oxoglutarate <=> 3-[(4-Bromophenyl)sulfanyl]-2-oxopropanoate + L-Glutamate R04339 thiomorpholine-3-carboxylate:NAD+ 5,6-oxidoreductase; Thiomorpholine 3-carboxylate + NAD+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADH + H+ R04340 thiomorpholine-3-carboxylate:NADP+ 5,6-oxidoreductase; Thiomorpholine 3-carboxylate + NADP+ <=> 3,4-Dehydrothiomorpholine-3-carboxylate + NADPH + H+ R04341 alpha-N-peptidyl-L-glutamine amidohydrolase; alpha-N-Peptidyl-L-glutamine + H2O <=> alpha-N-Peptidyl-L-glutamate + Ammonia R04342 trans-5-O-(4-coumaroyl)-D-quinate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); p-Coumaroyl quinic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Chlorogenate + [Oxidized NADPH---hemoprotein reductase] + H2O R04343 UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase; UDP-D-galacturonate + Pectate <=> UDP + Pectate R04344 3beta-hydroxysteroid:NADP+ oxidoreductase; 5alpha-Androstan-3beta,17beta-diol + NADP+ <=> Dihydrotestosterone + NADPH + H+ R04345 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); 2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> 2,4-Dichloro-cis,cis-muconate R04346 2,4-dioxotetrahydropyrimidine-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase; 2,4-Dioxotetrahydropyrimidine D-ribonucleotide + Diphosphate <=> 5,6-Dihydrouracil + 5-Phospho-alpha-D-ribose 1-diphosphate R04347 5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferas; 5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme M + 2 Sodium cation(side 1) <=> 5,6,7,8-Tetrahydromethanopterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2) R04348 acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase; Acetyl-CoA + 2-Deoxystreptamine antibiotic <=> CoA + N3-Acetyl-2-deoxystreptamine antibiotic R04349 3,5-dibromo-4-hydroxybenzonitrile aminohydrolase; Bromoxynil + 2 H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia R04350 (2S)-2-amino-3-[3-hydroxy-4-oxopyridin-1(4H)-yl]propanoate 3-hydroxy-4H-pyrid-4-one-lyase (2-aminoprop-2-enoate-forming); L-Mimosine + H2O <=> 3-Hydroxy-4H-pyrid-4-one + Pyruvate + Ammonia R04352 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); Etiocholanolone + UDP-glucuronate <=> Etiocholan-3alpha-ol-17-one 3-glucuronide + UDP R04353 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); 2-Methoxyestrone + UDP-glucuronate <=> 2-Methoxyestrone 3-glucuronide + UDP R04354 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); 2-Methoxy-17beta-estradiol + UDP-glucuronate <=> 2-Methoxy-estradiol-17beta 3-glucuronide + UDP R04355 acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CO2 + Acyl-carrier protein R04356 malonyl-CoA:flavonol-3-O-beta-D-glucoside malonyltransferase; Malonyl-CoA + Flavonol 3-O-beta-D-glucoside <=> CoA + Flavonol 3-O-(6-O-malonyl-beta-D-glucoside) R04358 ATP:[DNA-directed RNA polymerase] phosphotransferase; ATP + [DNA-directed RNA polymerase] <=> ADP + Phospho-[DNA-directed RNA polymerase] R04359 UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-glucosyltransferase; UDP-glucose + Sarsasapogenin <=> UDP + Asparagoside A R04360 1-Alkyl-sn-glycero-3-phosphate + NADP+ <=> O-Alkylglycerone phosphate + NADPH + H+ R04361 acyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acyltransferase; Acyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acyl-1-alkyl-sn-glycero-3-phosphate R04362 1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase; 1-Alkyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkyl-sn-glycero-3-phosphate + Ethanolamine R04363 acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase; Acyl-CoA + 1-Alkyl-2-acetyl-sn-glycerol <=> CoA + 1-O-Alkyl-2-acetyl-3-acyl-sn-glycerol R04364 acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase; 2,3,4,5-Tetrahydrodipicolinate + Acetyl-CoA + H2O <=> N-Acetyl-L-2-amino-6-oxopimelate + CoA R04365 succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Succinyl-CoA + 2,3,4,5-Tetrahydrodipicolinate + H2O <=> CoA + N-Succinyl-2-L-amino-6-oxoheptanedioate R04366 linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Hydroxylinalool + [Oxidized NADPH---hemoprotein reductase] + H2O R04367 4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase; 4-Nitrophenyl-3-ketovalidamine <=> 4-Nitroaniline + 5-D-(5/6)-5-C-(Hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one R04368 m7G5'ppp5'X m7GMP phosphohydrolase; 7-Methylguanosine 5'-triphospho-5'-oligonucleotide + H2O <=> 7-Methylguanosine 5'-phosphate + Oligonucleotide 5'-diphosphate R04369 D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming); ATP + D-Alanine + Alanyl-poly(glycerolphosphate) <=> ADP + Orthophosphate + D-Alanyl-alanyl-poly(glycerolphosphate) R04370 benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase; Benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ <=> Benzyl 2-methyl-3-oxobutanoate + NADPH + H+ R04371 homoisocitrate hydro-lyase; Homoisocitrate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O R04372 D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase; D-myo-Inositol 3,4-bisphosphate + H2O <=> 1D-myo-Inositol 3-phosphate + Orthophosphate R04373 glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase; Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O <=> N-Acetyl-D-glucosamine + Glycoprotein phospho-D-mannose R04374 trans-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming); trans-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O R04375 2-Dehydro-3-deoxy-D-xylonate + NAD+ <=> 5-Hydroxy-2,4-dioxopentanoate + NADH R04376 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing); 3-(2,3-Dihydroxyphenyl)propanoate + Oxygen <=> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate R04377 UDP-alpha-D-glucose:1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol 6-glucosyltransferase; 3-D-Glucosyl-1,2-diacylglycerol + UDP-glucose <=> Diglucosyldiacylglycerol + UDP R04378 1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide:pyrophosphate phosphoribosyltransferase; 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate R04379 5-carboxymethyl-2-hydroxymuconate delta2,delta4-2-oxo,delta3-isomerase; 5-Carboxymethyl-2-hydroxymuconate <=> 5-Carboxy-2-oxohept-3-enedioate R04380 5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase; 5-Carboxy-2-oxohept-3-enedioate <=> 2-Hydroxyhepta-2,4-dienedioate + CO2 R04382 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate lyase; 4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate <=> 2 5-Dehydro-4-deoxy-D-glucuronate R04383 5-dehydro-4-deoxy-D-glucuronate ketol-isomerase; 5-Dehydro-4-deoxy-D-glucuronate <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate R04384 methanol:[Co(I) corrinoid protein] Co-methyltransferase; Methanol + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + H2O R04385 biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming); ATP + Holo-[carboxylase] + HCO3- <=> ADP + Orthophosphate + Carboxybiotin-carboxyl-carrier protein R04386 carboxybiotin-carboxyl-carrier-protein:acetyl-CoA carboxytransferase; Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein <=> Malonyl-CoA + Holo-[carboxylase] R04387 diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase; Diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ <=> Diethyl 2-methyl-3-oxosuccinate + NADPH + H+ R04388 ATP:guanidinoethyyl-methyl-phosphate phosphotransferase; ATP + Guanidinoethyl methyl phosphate <=> ADP + N'-Phosphoguanidinoethyl methyl phosphate R04389 heparosan-N-sulfate-D-glucuronate glucurono-5-epimerase; poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase; Heparosan-N-sulfate D-glucuronate <=> Heparosan-N-sulfate L-iduronate R04390 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase; alpha-Aminoadipoyl-S-acyl enzyme + NADPH + H+ <=> L-2-Aminoadipate 6-semialdehyde + Holo-Lys2 + NADP+ R04391 ATP:pantothenate 4'-phosphotransferase; ATP + N-((R)-Pantothenoyl)-L-cysteine <=> ADP + (R)-4'-Phosphopantothenoyl-L-cysteine R04392 pregna-4,9(11)-diene-3,20-dione,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing); Pregna-4,9(11)-diene-3,20-dione + Reduced acceptor + Oxygen <=> 9,11alpha-Epoxypregn-4-ene-3,20-dione + Acceptor + H2O R04393 protein-N(pi)-phosphohistidine:lactose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate R04394 protein-N(pi)-phosphohistidine:salicin 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Salicin <=> Protein histidine + Salicin 6-phosphate R04396 S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase; S-Adenosyl-L-methionine + 1,4-alpha-D-Glucooligosaccharide <=> S-Adenosyl-L-homocysteine + Oligosaccharide containing 6-methyl-D-glucose units R04397 2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase; 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H2O <=> Acetate + 2-(Hydroxymethyl)-4-oxobutanoate + Ammonia + CO2 R04398 S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase; S-Adenosyl-L-methionine + Gossypetin <=> S-Adenosyl-L-homocysteine + Corniculatusin R04399 4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O R04400 (S)-tetrahydrocolumbamine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming); Isocorypalmine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Canadine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04401 ATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase; ATP + [Isocitrate dehydrogenase (NADP+)] <=> ADP + [Isocitrate dehydrogenase (NADP+)] phosphate R04403 ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4-O'-phosphotransferase; ATP + Low-density lipoprotein L-serine <=> ADP + Low-density lipoprotein O-phospho-L-serine R04404 phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate R04405 5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase; 5-Methyltetrahydropteroyltri-L-glutamate + L-Homocysteine <=> Tetrahydropteroyltri-L-glutamate + L-Methionine R04409 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase; trans-Cinnamoyl beta-D-glucoside + Methanol <=> Methyl cinnamate + D-Glucose R04410 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase; trans-Cinnamoyl beta-D-glucoside + Ethanol <=> Ethyl cinnamate + D-Glucose R04411 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase; trans-Cinnamoyl beta-D-glucoside + Alcohol <=> Alkyl cinnamate + D-Glucose R04412 vomifoliol:NAD+ oxidoreductase; (6S,9R)-Vomifoliol + NAD+ <=> Dehydrovomifoliol + NADH + H+ R04413 acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase; Acyl-CoA + 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine <=> CoA + O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine R04416 (3R)-3-hydroxydecanoyl-[acyl-carrier protein] hydro-lyase; (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> cis-Dec-3-enoyl-[acp] + H2O R04418 5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase; 2-Hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADH + H+ R04419 5-carboxymethyl-2-hydroxymuconic-semialdehyde:NADP+ oxidoreductase; 2-Hydroxy-5-carboxymethylmuconate semialdehyde + NADP+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH + H+ R04420 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-Methyl-5-thio-D-ribose 1-phosphate <=> S-Methyl-5-thio-D-ribulose 1-phosphate R04421 S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase; S-Adenosyl-L-methionine + N-Benzoyl-4-hydroxyanthranilate <=> S-Adenosyl-L-homocysteine + N-Benzoyl-4-methoxyanthranilate R04422 alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase; alpha-D-Aldosyl beta-D-fructoside + D-Aldose <=> D-Aldose + alpha-D-Aldosyl beta-D-fructoside R04423 UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + N-Acetyl-alpha-D-galactosaminyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside R04424 (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]; 2-Methylcitrate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O R04425 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase; (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate <=> (Z)-But-2-ene-1,2,3-tricarboxylate + H2O R04426 (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase; (2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+ R04427 S-adenosyl-L-methionine:zymosterol C-methyltransferase; S-Adenosyl-L-methionine + Zymosterol <=> S-Adenosyl-L-homocysteine + Fecosterol R04428 (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <=> But-2-enoyl-[acyl-carrier protein] + H2O R04429 butyryl-[acp]:NAD+ trans-2-oxidoreductase; Butyryl-[acp] + NAD+ <=> But-2-enoyl-[acyl-carrier protein] + NADH + H+ R04430 butyryl-[acp]:NADP+ trans-2-oxidoreductase; Butyryl-[acp] + NADP+ <=> But-2-enoyl-[acyl-carrier protein] + NADPH + H+ R04431 UDP-alpha-D-galactose:D-galactosyl-(1->4)-beta-D-glucosyl-R 3-beta-galactosyltransferase; UDP-alpha-D-galactose + D-Galactosyl-(1->4)-beta-D-glucosyl-R <=> UDP + D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R R04432 propanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Electron-transferring flavoprotein + Propanoyl-CoA <=> Reduced electron-transferring flavoprotein + Propenoyl-CoA R04433 electron-transferring-flavoprotein:ubiquinone oxidoreductase; Reduced electron-transferring flavoprotein + Ubiquinone <=> Electron-transferring flavoprotein + Ubiquinol R04435 phosphoenolpyruvate:N-acetyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating); N-Acetylneuraminate 9-phosphate + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + Phosphoenolpyruvate + H2O R04436 S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine Nalpha-methyltransferase; S-Adenosyl-L-methionine + N,N-Dimethylhistidine <=> S-Adenosyl-L-homocysteine + Hercynine R04437 protein N6-(4-aminobutyl)-L-lysine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating); [eIF5A-precursor]-deoxyhypusine + Reduced acceptor + Oxygen <=> Protein N6-[(R)-4-amino-2-hydroxybutyl]-L-lysine + Acceptor + H2O R04438 dTDP-4-amino-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase; dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate <=> dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate R04439 (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing); (R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Acetolactate + NADPH + H+ R04440 (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing); (R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid + NADPH + H+ R04441 (R)-2,3-dihydroxy-3-methylbutanoate hydro-lyase; (R)-2,3-Dihydroxy-3-methylbutanoate <=> 3-Methyl-2-oxobutanoic acid + H2O R04443 L-1-Pyrroline-3-hydroxy-5-carboxylate + H2O <=> L-4-Hydroxyglutamate semialdehyde R04444 L-1-pyrroline-3-hydroxy-5-carboxylate:NAD+ oxidoreductase; L-1-Pyrroline-3-hydroxy-5-carboxylate + NAD+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADH + H+ R04445 L-1-pyrroline-3-hydroxy-5-carboxylate:NADP+ oxidoreductase; L-1-Pyrroline-3-hydroxy-5-carboxylate + NADP+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADPH + H+ R04446 1-Pyrroline-4-hydroxy-2-carboxylate + H2O <=> 2-Oxo-4-hydroxy-5-aminovalerate R04447 1-Pyrroline-4-hydroxy-2-carboxylate <=> Pyrrole-2-carboxylate + H2O R04448 ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase; ATP + 5-(2-Hydroxyethyl)-4-methylthiazole <=> ADP + 4-Methyl-5-(2-phosphooxyethyl)thiazole R04449 acetate:holo-[citrate-(pro-3S)-lyase] ligase (AMP-forming); ATP + Acetate + Holo-[citrate (pro-3S)-lyase] <=> AMP + Diphosphate + Acetyl-[citrate (pro-3S)-lyase] R04450 [citrate-(pro-3S)-lyase](acetyl-form) hydrolase; Acetyl-[citrate (pro-3S)-lyase] + H2O <=> Holo-[citrate (pro-3S)-lyase] + Acetate R04451 UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Estradiol-17alpha 3-D-glucuronoside <=> UDP + 17alpha-(N-Acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside R04452 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase; 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Acetate R04453 4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP+ 6-oxidoreductase; 4-Carboxy-2-hydroxymuconate semialdehyde + NADP+ + H2O <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate + NADPH + H+ R04455 hydrogen:N5,N10-methenyltetraydromethanopterin oxidoreductase; 5,10-Methenyltetrahydromethanopterin + Hydrogen <=> 5,10-Methylenetetrahydromethanopterin + H+ R04456 5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase; 5,10-Methylenetetrahydromethanopterin + Coenzyme F420 + H+ <=> 5,10-Methenyltetrahydromethanopterin + Reduced coenzyme F420 R04457 5-amino-6-(D-ribitylamino)uracil butanedionetransferase; 5-Amino-6-(1-D-ribitylamino)uracil + L-3,4-Dihydroxybutan-2-one 4-phosphate <=> 6,7-Dimethyl-8-(D-ribityl)lumazine + 2 H2O + Orthophosphate R04458 6,7-Dimethyl-8-(D-ribityl)lumazine <=> 7-Hydroxy-6-methyl-8-ribityllumazine R04459 variant-surface-glycoprotein-1,2-didecanoyl-sn-phosphatidyl-inositol inositolphosphohydrolase; Variant-surface-glycoprotein 1,2-dimyristyl-sn-phosphatidylinositol <=> Soluble variant-surface-glycoprotein + 1,2-Dimyristyl-sn-glycerol R04460 N-hydroxy-L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); N-Hydroxy-L-tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O R04461 1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase; 1,2-Bis(3,4-dimethoxyphenyl)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + 1-(3,4-Dimethoxyphenyl)ethane-1,2-diol + H2O R04463 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming); ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate R04464 5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase; 5,10-Methylenetetrahydromethanopterin + Reduced coenzyme F420 <=> 5-Methyl-5,6,7,8-tetrahydromethanopterin + Coenzyme F420 R04466 acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase; Acetyl-CoA + Heparan sulfate alpha-D-glucosaminide <=> CoA + Heparan sulfate N-acetyl-alpha-D-glucosaminide R04467 N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate R04469 UDP-alpha-D-galactose:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol 6-alpha-D-galactosyltransferase; 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-alpha-D-galactose <=> Digalactosyl-diacylglycerol + UDP R04470 digalactosyl-diacylglycerol galactohydrolase; Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose R04471 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase; 3-beta-D-Galactosyl-sn-glycerol + 2 Fatty acid <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O R04472 3-beta-D-galactosyl-1,2-diacylglycerol:mono-beta-D-galactosyldiacyl glycerol beta-D-galactosyltransferase; 2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 1,2-Diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 1,2-Diacyl-sn-glycerol R04473 acyl-[acyl-carrier protein]:D-galactosylacylglycerol O-acyltransferase; Acyl-[acyl-carrier protein] + 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> Acyl-carrier protein + 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol R04474 3-beta-D-galactosyl-1,2-diacylglycerol:mono-beta-D-galactosylglycerol acyltransferase; 2 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol <=> 2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol + Acyl1-monogalactosyl-diacylglycerol R04475 N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate amino-transferase; N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate R04476 3'-phosphoadenylylsulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase; 3'-Phosphoadenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate <=> Adenosine 3',5'-bisphosphate + UDP-N-acetyl-D-galactosamine 4,6-bissulfate R04477 UDP-N-acetyl-alpha-D-mannosaminouronate:lipid I N-acetyl-alpha-D-mannosaminouronosyltransferase; UDP-N-acetyl-D-mannosaminouronate + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP R04478 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase; 4-Carboxy-4-hydroxy-2-oxoadipate <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + H2O R04479 1-(5-Phosphoribosyl)imidazole-4-acetate + H2O <=> (1-Ribosylimidazole)-4-acetate + Orthophosphate R04480 acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase; Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA R04481 S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase; S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine R04482 4-carboxy-2-oxo-3-hexenedioate delta2,delta4-2-oxo,delta3-isomerase; 4-Carboxy-2-oxo-3-hexenedioate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate R04483 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADH + H+ R04484 acetyl-CoA:polysialic-acid O-acetyltransferase; Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-7 R04486 glycodeoxycholate amidohydrolase; Glycodeoxycholate + H2O <=> Deoxycholic acid + Glycine R04487 taurodeoxycholate amidohydrolase; Taurodeoxycholate + H2O <=> Deoxycholic acid + Taurine R04488 4-Carboxy-2-hydroxymuconate semialdehyde + H2O <=> 4-Methylene-2-oxoglutarate + Formate R04489 2-Hydroxy-2-hydropyrone-4,6-dicarboxylate <=> 4-Carboxy-2-hydroxymuconate semialdehyde R04490 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase; 5-(4-Acetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(4-Hydroxybut-1-ynyl)-2,2'-bithiophene + Acetate R04491 UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase; UDP-glucose + 5-(D-Galactosyloxy)-L-lysine-procollagen <=> UDP + 1,2-D-Glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen R04493 UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Lactosylceramide <=> UDP + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide R04494 UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl diphosphodolichol N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Diacetylchitobiosyldiphosphodolichol R04495 UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminylglycopeptide 4-beta-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-glycopeptide <=> UDP + beta-D-Galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide R04496 S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase; S-Adenosyl-L-methionine + Protein C-terminal S-farnesyl-L-cysteine <=> S-Adenosyl-L-homocysteine + Protein C-terminal S-farnesyl-L-cysteine methyl ester R04498 1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase; 1-O-Galloyl-beta-D-glucose + 1,2,3,6-Tetrakis-O-galloyl-beta-D-glucose <=> D-Glucose + Pentagalloylglucose R04500 2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid R04501 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Ferricytochrome b5 + H2O R04502 GDPmannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase; GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol R04503 protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase; Protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine + H2O <=> D-Glucose + Protein beta-D-galactosyl-L-hydroxylysine R04504 1-Phosphatidyl-1D-myo-inositol 3-phosphate + 2 ATP <=> Phosphatidylinositol-3,4,5-trisphosphate + 2 ADP R04505 S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase; S-Adenosyl-L-methionine + Tomentin <=> S-Adenosyl-L-homocysteine + Chrysosplenol D + H+ R04506 3alpha,7alpha-dihydroxy-5beta-cholestan-26-al:NAD+ oxidoreductase; 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NAD+ + H2O <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + NADH + H+ R04507 3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming); ATP + 3alpha,7alpha-Dihydroxy-5beta-cholestanate + CoA <=> AMP + Diphosphate + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA R04509 ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase; ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate R04510 4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase; 4-Methylmuconolactone <=> 3-Methylmuconolactone R04511 phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase; Phosphatidylglycerol + Membrane-derived-oligosaccharide D-glucose <=> 1,2-Diacyl-sn-glycerol + Membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose R04512 3-D-glucuronosyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase; 3-D-Glucuronosyl-N2,6-disulfo-beta-D-glucosamine + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate R04513 phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase; Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate R04514 phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase; Phosphatidylcholine + Retinol-(cellular-retinol-binding-protein) <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl-ester-(cellular-retinol-binding-protein) R04515 (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Xylonate + CO2 R04517 (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD+ 15-oxidoreductase; (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD+ <=> 15-OxoETE + NADH + H+ R04518 (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NADP+ 15-oxidoreductase; (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NADP+ <=> 15-OxoETE + NADPH + H+ R04519 [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol polysaccharidetransferase; bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuranoyl-N-acetyl-D-glucosaminyltransferase; Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-A2pm-D-Ala-D-Ala)]n-diphosphoundecaprenol <=> di-trans,poly-cis-Undecaprenyl diphosphate + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-A2pm-D-Ala-D-Ala)]n-diphosphoundecaprenol R04520 geranylgeranyl-diphosphate:3-(O-geranylgeranyl)-sn-glycerol 1-phosphate geranylgeranyltransferase; Geranylgeranyl diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate R04522 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase; DDT <=> 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + Hydrochloric acid R04523 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,NADPH:oxygen oxidoreductase (N-oxide-forming); 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + Oxygen <=> 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide + NADP+ + H2O R04524 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate:NAD+ 5-oxidoreductase; 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+ <=> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate + H2O + NAD+ R04525 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase; 5-(3,4-Diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(3-Hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + Acetate R04526 UDP-apiose:apigenin 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase; UDP-apiose + Apigenin 7-O-beta-D-glucoside <=> UDP + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside] R04527 peptide-D-galactosyl-N-acetyl-alpha-D-galactosaminyl-L-serine D-galactosyl-N-acetyl-galactosaminohydrolase; Peptide beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-serine + H2O <=> beta-D-Galactosyl-(1->3)-N-acetyl-D-galactosamine + [Protein]-L-serine R04529 UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine:2-oxoglutarate aminotransferase; UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + 2-Oxoglutarate <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate R04531 UDP-alpha-D-galactose:N-acetyllactosamine 3-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyllactosamine <=> UDP + alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosamine R04532 CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D--glucosamine alpha-2,6-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + N-Acetyllactosamine <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine R04533 (3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase; (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+ R04534 (3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH R04535 (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> trans-Dec-2-enoyl-[acp] + H2O R04536 (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+ R04537 (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <=> trans-Oct-2-enoyl-[acp] + H2O R04538 (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase; (E)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide <=> (Z)-2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide R04540 coenzyme B:coenzyme M:methanophenazine oxidoreductase; Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Dihydromethanophenazine <=> Coenzyme B + Coenzyme M + Methanophenazine R04541 2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase; Coenzyme B + 2-(Methylthio)ethanesulfonate <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Methane R04542 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphate phosphohydrolase; [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O <=> [Hydroxymethylglutaryl-CoA reductase (NADPH)] + Orthophosphate R04543 (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+ R04544 (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <=> trans-Hexadec-2-enoyl-[acp] + H2O R04545 ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate R04546 Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA R04547 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + FADH2 R04548 UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose; UDP-alpha-D-galactose + alpha-L-Fucosyl-1,2-beta-D-galactoside <=> UDP + alpha-D-Galactosyl-(1,3)-[alpha-L-fucosyl-(1,2)]-D-galactoside R04549 UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-beta-D-glucosaminyl 1-phosphate phosphohydrolase; UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + H2O <=> UMP + Lipid X R04550 (3R)-3-hydroxymyristoyl-[acyl-carrier protein]:UDP-3-O-[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine N-acetyltransferase; UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Acyl-carrier protein R04552 (13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase; Alprostadil + NADP+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+ R04553 GDP-L-fucose:beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4-fucosyltransferase; GDP-L-fucose + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R <=> GDP + 1,3-beta-D-Galactosyl-(alpha-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl-R R04555 ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase; ATP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] <=> ADP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate R04556 (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD+ delta13-oxidoreductase; (5Z)-11alpha-Hydroxy-9,15-dioxoprostanoate + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+ R04557 (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NADP+ delta13-oxidoreductase; (5Z)-11alpha-Hydroxy-9,15-dioxoprostanoate + NADP+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADPH + H+ R04558 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate-lyase (L-glutamine-hydrolysing; 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide-forming); N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate R04559 1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase; 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide R04560 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide R04562 biotin:apo-[acetyl-CoA:carbondioxide ligase (ADP-forming)] ligase (AMP-forming); ATP + Biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Acetyl-CoA:carbon-dioxide ligase (ADP-forming)] R04563 biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming); ATP + Biotin + Apo-[methylmalonyl-CoA:pyruvate carboxytransferase] <=> AMP + Diphosphate + [Methylmalonyl-CoA:pyruvate carboxytransferase] R04564 CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R R04565 (13E)-(15S)-15-Hydroxy-9-oxoprosta-10,13-dienoate <=> (13E)-(15S)-15-Hydroxy-9-oxoprosta-11,13-dienoate R04566 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+ R04567 (R)-3-hydroxytetradecanoly-[acyl-carrier-protein]:UDP-N-acetyl-glucosamine 3-O-(3-hydroxytetradecanoyl)transferase; (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine <=> Acyl-carrier protein + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine R04568 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O R04570 5-pyridoxate,NADPH:oxygen oxidoreductase (ring-opening); 3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + Oxygen + NADPH + H+ <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+ R04571 plasmanylethanolamine,ferrocytochrome b5:oxygen oxidoreductase (plasmenylethanolamine-forming); 1-Alkyl-2-acylglycerophosphoethanolamine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Ferricytochrome b5 + 2 H2O R04573 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:alanyl-D-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) R04575 UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> UDP + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R R04576 cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase; cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide R04577 UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase; UDP-glucose + Nuatigenin <=> UDP + Nuatigenin 3beta-D-glucopyranoside R04578 1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one <=> 4,5-Dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one R04579 UDP-alpha-D-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-beta-D-glucosyltransferase; UDP-glucose + DIMBOA <=> UDP + DIMBOA-glucoside R04580 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming); ATP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + CoA <=> AMP + Diphosphate + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA R04581 CDPabequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase; CDP-abequose + alpha-D-Mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol <=> CDP + alpha-D-Abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol R04582 biotin:apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]; ATP + Biotin + Apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Propionyl-CoA:carbon-dioxide ligase (ADP-forming)] R04583 CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + GM3 <=> CMP + GD3 R04584 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide R04586 N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylhexosaminohydrolase; N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GM3 + N-Acetyl-D-galactosamine R04587 UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase; UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O <=> UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + Acetate R04588 S-acetylphosphopantetheine:deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)] S-acetyltransferase; S-Acetylphosphopantetheine + Holo-[citrate (pro-3S)-lyase] <=> Pantetheine 4'-phosphate + Acetyl-[citrate (pro-3S)-lyase] R04589 ATP:dephopho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] phopshotransferase; ATP + Dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)]kinase] <=> ADP + [[Hydroxymethylglutaryl-CoA reductase (NADPH)]kinase] R04590 CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R R04591 1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming); ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole R04592 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + FADH2 R04593 3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate <=> 5-Pyridoxolactone + H2O R04594 N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H2O <=> alpha-Ribazole + Orthophosphate R04596 CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein R04597 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing); 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Oxygen <=> 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate R04598 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing); Stizolobate + NADH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+ R04599 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing); Stizolobate + NADPH + H+ <=> 4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ R04600 3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing); Stizolobinate + NADH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NAD+ R04601 3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing); Stizolobinate + NADPH + H+ <=> 5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ R04602 5-amino-4-chloro-2-(2',3'-dihydroxyphenyl)-3(2H)-pyridazinone 1',2'-oxidoreductase (decyclizing); 5-Amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + Oxygen <=> 5-Amino-4-chloro-2-(5-hydroxymuconoyl)-3(2H)-pyridazinone R04603 UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine + D-Glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan <=> UDP + N-Acetyl-beta-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan R04604 biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming); ATP + Biotin + Apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] R04606 UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase; UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Lipid X <=> UDP + Lipid A disaccharide R04607 UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein D-glucuronosyltransferase; UDP-glucuronate + 3-beta-D-Galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein R04608 methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyl-trideca-2,6-dienoate acylhydrolase; Juvenile hormone II + H2O <=> Juvenile hormone II acid + Methanol R04609 (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase; (5Z,9E,14Z)-(8xi,11R,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid + H2O <=> (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-Trihydroxyicosa-5,9,14-trienoate R04610 UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide R04611 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine carboxypeptidase; UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanine + D-Alanine R04613 L-alanyl-tRNA(Ala):UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase; UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + L-Alanyl-tRNA <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala) R04615 UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl1,4-beta-D-glucosylceramide beta-1,4-N-acetyl-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + N-Acetyl-D-galactosaminyl-1,4-beta-N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide R04616 20-OH-Leukotriene B4 <=> 20-COOH-Leukotriene B4 R04617 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate:D-alanyl-D-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine R04618 malonyl-CoA:flavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Malonyl-CoA + Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside] <=> CoA + Malonylapiin R04619 UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 1,3-alpha-D-Mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose <=> UDP + 1,3-alpha-D-Mannosyl-(1,2-N-acetyl-alpha-D-glucosaminyl)-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose R04620 7,8-dihydroneopterin-3'-triphosphate phosphohydrolase (alkaline optimum); 7,8-Dihydroneopterin 3'-triphosphate + 3 H2O <=> 7,8-Dihydroneopterin + 3 Orthophosphate R04621 7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O R04622 7,8-Dihydroneopterin + Acceptor <=> Neopterin + Reduced acceptor R04623 (+/-)-5-[(tert-butylamino)-2'-hydroxypropoxyl]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase; (+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ <=> (+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+ R04630 CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + GA2 <=> CMP + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide R04631 UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> UDP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide R04632 CMP-N-acetylneuraminate + N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD2 R04633 D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D- galactosyl-D-glucosylceramide galactohydrolase; D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + D-Galactose R04634 N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> GA2 + N-Acetylneuraminate R04635 CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactose-1,3-(alpha-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R R04636 UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->3)-[N-acetyl-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R 3-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R R04638 7,8-dihydroneopterin 3'-triphosphate diphosphohydrolase; 7,8-Dihydroneopterin 3'-triphosphate + H2O <=> Dihydroneopterin phosphate + Diphosphate R04639 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate hydrolase; 7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine R04640 N-(5'-phospho-D-ribosylformimino)-5-amino-1- (5''-phospho-D-ribosyl)-4-imidazolecarboxamide ketol-isomerase; 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase; 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide <=> N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide R04641 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase; 1-(4-Amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O <=> 1-(4-Hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + Ammonia R04642 UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2)-(N-acetyl-beta-D-glucosaminyl-1,4)-alpha-D-mannosyl-R R04643 3'-phosphoadenylylsulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase; 3'-Phosphoadenylyl sulfate + alpha-D-Glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol <=> Adenosine 3',5'-bisphosphate + 6-Sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol R04644 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-alpha-D-galactose <=> Ceramidepentasaccharide + UDP R04645 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP-N-acetyl-D-galactosamine <=> Ceramidepentasaccharide + UDP R04646 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + GDP-L-fucose <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + GDP R04647 CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + GA1 <=> CMP + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide R04648 CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide R04649 CMP-N-acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GD1b R04650 D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + N-Acetylneuraminate <=> N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O R04653 UDP-N-acetyl-D-glucosamine:glycoprotein (N-acetyl-D-glucosamine to alpha-D-mannosyl-1,6-(R1)-beta-D-mannosyl-R2) beta-1,2-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + alpha-D-Mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R R04654 UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide R04656 CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide R04657 ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-alpha-phosphate 4-O'-phosphotransferase; ATP + Lipid A disaccharide <=> ADP + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate R04658 CMP-3-deoxy-D-manno-oct-2-ulosonate:lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase; 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + CMP-3-deoxy-D-manno-octulosonate <=> 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP R04659 UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide R04660 CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GT1a R04661 CMP-N-acetylneuraminate + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <=> CMP + GT1b R04662 UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-beta-D-mannosyl-R R04665 UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2,6-Bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R R04666 (R)-3-ureidoisobutyrate amidohydrolase; (R)-3-Ureidoisobutyrate + H2O <=> (R)-3-Amino-2-methylpropanoate + CO2 + Ammonia R04667 7-Dehydrodesmosterol + Reduced acceptor <=> 5alpha-Cholesta-7,24-dien-3beta-ol + Acceptor R04670 24,25-Dihydrolanosterol + NADPH <=> 4alpha-Methylcholesta-8-en-3beta-ol + NADP+ R04671 4alpha-methylcholesta-8-en-3beta-ol delta7-delta8-isomerase; 4alpha-Methylcholesta-8-en-3beta-ol <=> Methostenol R04672 (S)-2-acetolactate pyruvate-lyase (carboxylating); (S)-2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate R04673 (S)-2-aceto-2-hydroxybutanoate pyruvate-lyase (carboxylating); 2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate R04674 N-methylhistamine:oxygen oxidoreductase (deaminating); N-Methylhistamine + H2O + Oxygen <=> Methylimidazole acetaldehyde + Ammonia + Hydrogen peroxide R04675 17alpha-hydroxypregnenolone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating); 17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha,21-Dihydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O R04676 17alpha,20alpha-dihydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving); 17alpha,20alpha-Dihydroxycholesterol + 2 Oxygen + 4 H+ + 4 Reduced adrenal ferredoxin <=> 17alpha-Hydroxypregnenolone + 4-Methylpentanal + 3 H2O + 4 Oxidized adrenal ferredoxin R04678 16alpha-hydroxyandrost-4-ene-3,17-dione delta5-delat4-isomerase; 16alpha-hydroxydehydroepiandrosterone:NAD+ 3-oxidoreductase; 16alpha-Hydroxyandrost-4-ene-3,17-dione + H+ + NADH <=> 16alpha-Hydroxydehydroepiandrosterone + NAD+ R04681 estriol:NAD+ 17-oxidoreductase; Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+ R04682 estriol:NADP+ 17-oxidoreductase; Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+ R04683 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific); UDP-glucuronate + Estriol <=> UDP + 16-Glucuronide-estriol R04684 Aminoacyl-tRNA + Phosphatidylglycerol <=> Aminoacyl-phosphatidylglycerol + tRNA R04685 peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase; Aminoacyl-tRNA + Peptidyl-tRNA <=> tRNA + Peptidyl-aminoacyl-tRNA R04686 trans-beta-D-Glucosyl-2-hydroxycinnamate <=> cis-beta-D-Glucosyl-2-hydroxycinnamate R04687 2,5-diaminohexanoate:NAD+ oxidoreductase (deaminating); (2R,5S)-2,5-Diaminohexanoate + H2O + NAD+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADH + H+ R04688 2,5-diaminohexanoate:NADP+ oxidoreductase (deaminating); (2R,5S)-2,5-Diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + Ammonia + NADPH + H+ R04690 (S)-cheilanthifoline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming); (S)-Cheilanthifoline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Stylopine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04691 Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-Methylstylopine + S-Adenosyl-L-homocysteine R04692 S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase; S-Adenosyl-L-methionine + (S)-Coclaurine <=> S-Adenosyl-L-homocysteine + (S)-N-Methylcoclaurine + H+ R04693 monophenol,L-dopa:oxygen oxidoreductase; (S)-N-Methylcoclaurine + Oxygen + Reduced acceptor <=> 3'-Hydroxy-N-methyl-(S)-coclaurine + H2O + Acceptor R04694 (S)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling); (S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Berbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04695 (R)-reticuline:NADP+ oxidoreductase; (R)-Reticuline + NADP+ <=> 1,2-Dehydroreticuline + NADPH R04696 (R)-reticuline,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-C phenol-coupling); (R)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salutaridine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04697 salutaridinol:NADP+ 7-oxidoreductase; Salutaridinol + NADP+ <=> Salutaridine + NADPH + H+ R04699 protopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating); Protopine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxyprotopine + [Oxidized NADPH---hemoprotein reductase] + H2O R04700 (S)-cis-N-methylstylopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating); (S)-cis-N-Methylstylopine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Protopine + [Oxidized NADPH---hemoprotein reductase] + H2O R04701 6-Hydroxyprotopine <=> Dihydrosanguinarine + 2 H2O R04702 dihydrosanguinarine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10-hydroxylating); Dihydrosanguinarine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 10-Hydroxydihydrosanguinarine + [Oxidized NADPH---hemoprotein reductase] + H2O R04703 dihydrosanguinarine:oxygen oxidoreductase; Dihydrosanguinarine + Oxygen + H+ <=> Sanguinarine + Hydrogen peroxide R04705 S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase; S-Adenosyl-L-methionine + 12-Hydroxydihydrochelirubine <=> S-Adenosyl-L-homocysteine + Dihydromacarpine + H+ R04706 dihydrochelirubine:oxygen oxidoreductase; Dihydrochelirubine + Oxygen + H+ <=> Chelirubine + Hydrogen peroxide R04707 S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase; S-Adenosyl-L-methionine + 10-Hydroxydihydrosanguinarine <=> S-Adenosyl-L-homocysteine + Dihydrochelirubine + H+ R04708 dihydrochelirubine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Dihydrochelirubine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxydihydrochelirubine + [Oxidized NADPH---hemoprotein reductase] + H2O R04709 malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase; 3 Malonyl-CoA + 3-Hydroxybenzoyl-CoA <=> 4 CoA + 2,3',4,6-Tetrahydroxybenzophenone + 3 CO2 R04710 protein-glycine,dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving); S-Adenosyl-L-methionine + Dihydroflavodoxin + Protein glycine <=> 5'-Deoxyadenosine + L-Methionine + Flavodoxin semiquinone + Protein glycin-2-yl radical R04711 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase; S-Adenosyl-L-methionine + 3-Hexaprenyl-4,5-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Hexaprenyl-4-hydroxy-5-methoxybenzoate + H+ R04713 S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinolie N- methyltransferase; S-Adenosyl-L-methionine + (R,S)-Tetrahydrobenzylisoquinoline <=> S-Adenosyl-L-homocysteine + N-Methyl-(R,S)-tetrahydrobenzylisoquinoline + H+ R04714 S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase; S-Adenosyl-L-methionine + 6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + Nororientaline + H+ R04715 S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase; S-Adenosyl-L-methionine + Tetrahydropapaveroline <=> S-Adenosyl-L-homocysteine + 6-O-Methylnorlaudanosoline + H+ R04716 S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase; S-Adenosyl-L-methionine + (S)-Tetrahydroprotoberberine <=> S-Adenosyl-L-homocysteine + (S)-cis-N-Methyl-7,8,13,14-tetrahydroprotoberberine R04717 S-adenosyl-L-methionine:[cytochrome c]-methionine S-methyltransferase; S-Adenosyl-L-methionine + [Cytochrome c] methionine <=> S-Adenosyl-L-homocysteine + [Cytochrome c] S-methylmethionine R04718 S-Adenosyl-L-methionine + Histone L-arginine <=> S-Adenosyl-L-homocysteine + Histone N(omega)-methyl-L-arginine R04719 S-Adenosyl-L-methionine + [Myeline basic protein] L-arginine <=> S-Adenosyl-L-homocysteine + [Myeline basic protein] N(omega)-methyl-L-arginine R04720 1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent); 1-Alkyl-2-arachidonyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine R04721 1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent); 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + 1-Alkyl-2-lyso-sn-glycero-3-phosphoethanolamine <=> 1-Alkyl-2-acylglycerophosphoethanolamine + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine R04722 1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase; 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + 1-Organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-Radyl-2-acetyl-sn-glycero-3-phospholipid + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine R04723 acetyl-CoA:salutaridinol 7-O-acetyltransferase; Acetyl-CoA + Salutaridinol <=> CoA + 7-O-Acetylsalutaridinol R04724 dodecanoyl-[acp]:NAD+ trans-2-oxidoreductase; Dodecanoyl-[acyl-carrier protein] + NAD+ <=> trans-Dodec-2-enoyl-[acp] + NADH + H+ R04725 dodecanoyl-[acp]:NADP+ trans-2-oxidoreductase; Dodecanoyl-[acyl-carrier protein] + NADP+ <=> trans-Dodec-2-enoyl-[acp] + NADPH + H+ R04726 dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CO2 + Acyl-carrier protein R04727 N- acetylarylalkylamine amidohydrolase; N-Acetylarylalkylamine + H2O <=> Arylalkylamine + Acetate R04728 phaseollidin-hydrate hydro-lyase; 16alpha-hydroxyprogesterone hydro-lyase; Phaseollidin hydrate <=> Phaseollidin + H2O R04729 (2S)-2-methylacyl-CoA 2-epimerase; (2S)-2-Methylacyl-CoA <=> (2R)-2-Methylacyl-CoA R04730 alpha-tubulin:L-tyrosine ligase (ADP-forming); ATP + Detyrosinated alpha-tubulin + L-Tyrosine <=> alpha-Tubulin + ADP + Orthophosphate R04731 4-aminoimidazole aminohydrolase; 5-Aminoimidazole + H2O <=> Imidazolone + Ammonia R04732 5-Aminoimidazole + CO2 <=> 5-Amino-4-imidazole carboxylate R04733 UTP:[protein-PII] uridylyltransferase; UTP + [Protein-PII] <=> Diphosphate + Uridylyl-[protein-PII] R04734 4a-hydroxytetrahydrobiopterin hydro-lyase; 4a-Hydroxytetrahydrobiopterin <=> Dihydrobiopterin + H2O R04736 L-2-amino-hexano-6-lactam racemase; L-Lysine 1,6-lactam <=> D-2-Aminohexano-6-lactam R04737 (S)-3-hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase; (S)-3-Hydroxyhexadecanoyl-CoA + NAD+ <=> 3-Oxopalmitoyl-CoA + NADH + H+ R04738 (S)-3-hydroxyhexadecanoyl-CoA hydro-lyase; (S)-3-Hydroxyhexadecanoyl-CoA <=> trans-Hexadec-2-enoyl-CoA + H2O R04739 (S)-3-hydroxytetradecanoyl-CoA:NAD+ oxidoreductase; (S)-3-Hydroxytetradecanoyl-CoA + NAD+ <=> 3-Oxotetradecanoyl-CoA + NADH R04740 (S)-3-hydroxytetradecanoyl-CoA hydro-lyase; (S)-3-Hydroxytetradecanoyl-CoA <=> trans-Tetradec-2-enoyl-CoA + H2O R04741 (S)-3-hydroxydodecanoyl-CoA:NAD+ oxidoreductase; (S)-3-Hydroxydodecanoyl-CoA + NAD+ <=> 3-Oxododecanoyl-CoA + NADH + H+ R04742 decanoyl-CoA:acetyl-CoA C-acyltransferase; Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA R04743 (S)-hydroxydecanoyl-CoA:NAD+ oxidoreductase; (S)-Hydroxydecanoyl-CoA + NAD+ <=> 3-Oxodecanoyl-CoA + NADH + H+ R04744 (S)-hydroxydecanoyl-CoA hydro-lyase; (S)-Hydroxydecanoyl-CoA <=> trans-Dec-2-enoyl-CoA + H2O R04745 (S)-hydroxyoctanoyl-CoA:NAD+ oxidoreductase; (S)-3-Hydroxyoctanoyl-CoA + NAD+ <=> 3-Oxooctanoyl-CoA + NADH + H+ R04746 (S)-hydroxyoctanoyl-CoA hydro-lyase; (S)-3-Hydroxyoctanoyl-CoA <=> trans-Oct-2-enoyl-CoA + H2O R04747 hexanoyl-CoA:acetyl-CoA C-acyltransferase; Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA R04748 (S)-hydroxyhexanoyl-CoA:NAD+ oxidoreductase; (S)-Hydroxyhexanoyl-CoA + NAD+ <=> 3-Oxohexanoyl-CoA + NADH + H+ R04749 (S)-hydroxyhexanoyl-CoA hydro-lyase; (S)-Hydroxyhexanoyl-CoA <=> trans-Hex-2-enoyl-CoA + H2O R04751 hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2 R04753 trans-Dec-2-enoyl-CoA reductase; Decanoyl-CoA + NADP+ <=> trans-Dec-2-enoyl-CoA + NADPH + H+ R04754 decanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Decanoyl-CoA + FAD <=> trans-Dec-2-enoyl-CoA + FADH2 R04756 cis,cis-3,6-dodecadienoyl-CoA delta3-cis-delta2-trans-isomerase; cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA R04758 11beta-hydroxyandrost-4-ene-3,17-dione:NADP+ 11-oxidoreductase; 11beta-Hydroxyandrost-4-ene-3,17-dione + NADP+ <=> Adrenosterone + NADPH + H+ R04759 19-hydroxyandrostenedione,NADPH---hemoprotein reductase:oxygen 19-oxidoreductase; 19-Hydroxyandrost-4-ene-3,17-dione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Oxoandrost-4-ene-3,17-dione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04760 7alpha-Hydroxytestosterone + Acceptor <=> 7alpha-Hydroxyandrost-4-ene-3,17-dione + Reduced acceptor R04761 19-hydroxytestosterone,NADPH---hemoprotein reductase:oxygen 19-oxidoreductase; 19-Hydroxytestosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Oxotestosterone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R04762 S-adenosyl-L-methionine:2-hydroxyestrone O-methyltransferase; 2-Hydroxyestrone + S-Adenosyl-L-methionine <=> 2-Methoxyestrone + S-Adenosyl-L-homocysteine R04763 Desmosterol + S-Adenosyl-L-methionine <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + S-Adenosyl-L-homocysteine R04764 2-Hydroxyestradiol + S-Adenosyl-L-methionine <=> 2-Methoxy-17beta-estradiol + S-Adenosyl-L-homocysteine R04768 dihydromacarpine:oxygen oxidoreductase; Dihydromacarpine + Oxygen + H+ <=> Macarpine + Hydrogen peroxide R04769 salutaridinol 7-O-acetate acetate-lyase (thebaine forming); 7-O-Acetylsalutaridinol <=> Thebaine + Acetate R04770 selenomethionine methanethiol-lyase (deaminating); L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate R04771 ATP:L-selenomethione S-adenosyltransferase; ATP + L-Selenomethionine + H2O <=> Orthophosphate + Diphosphate + Se-Adenosylselenomethionine R04772 S-adenosyl-L-methionine:L-methionine S-methyltransferase; S-Adenosyl-L-methionine + L-Selenomethionine <=> S-Adenosyl-L-homocysteine + Se-Methylselenomethionine R04773 selenomethionine:tRNAMet ligase (AMP-forming); ATP + L-Selenomethionine + tRNA(Met) <=> AMP + Diphosphate + Selenomethionyl-tRNA(Met) R04774 L-Selenomethionine <=> Selenohomocysteine + Activated methyl group R04775 L-Selenomethionine <=> Selenomethionine Se-oxide R04776 phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase; L-Glutamate + 4-Hydroxyphenylacetyl-CoA <=> CoA + 4-Hydroxyphenylacetylglutamic acid R04777 4-Hydroxyphenylacetyl-CoA + Glycine <=> p-Hydroxyphenylacetylglycine + CoA R04779 ATP:D-fructose-6-phosphate 1-phosphotransferase; ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate R04780 beta-D-fructose 1,6-bisphosphate 1-phosphohydrolase; beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate R04781 4-carboxy-4-hydroxy-2-oxoadipate hydro-lyase; 4-Carboxy-4-hydroxy-2-oxoadipate <=> 4-Carboxy-2-oxo-3-hexenedioate + H2O R04782 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); Diimine + 2 e- + 2 H+ <=> Hydrazine R04783 3-ketolactose galactohydrolase; 3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose R04784 (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + H2O <=> L-Lyxonate + CO2 R04785 L-dehydroascorbate lactonohydrolase; Dehydroascorbate + H2O <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate R04786 15-cis-phytoene:plastoquinone oxidoreductase; all-trans-Phytoene + Acceptor <=> all-trans-Phytofluene + Reduced acceptor R04787 15-cis-phytoene:acceptor oxidoreductase; all-trans-Phytofluene + Acceptor <=> all-trans-zeta-Carotene + Reduced acceptor R04789 5-Cholestene + Oxygen + NADPH + H+ <=> 5,6beta-Epoxy-5beta-cholestane + NADP+ + H2O R04790 5-Cholestene + NADPH + Oxygen + H+ <=> 5,6alpha-Epoxy-5alpha-cholestane + NADP+ + H2O R04791 5,6beta-Epoxy-5beta-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol R04792 5,6beta-epoxy-5beta-cholestan-3beta-ol hydrolase; Cholesterol-5beta,6beta-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol R04794 5,6alpha-Epoxy-5alpha-cholestane + H2O <=> 5alpha-Cholestan-5alpha,6beta-diol R04795 Phytyl diphosphate + Chlorophyllide <=> Bacteriopheophytin + Magnesium cation + Diphosphate R04798 zeta-carotene,hydrogen-donor:oxygen oxidoreductase; all-trans-zeta-Carotene + Reduced acceptor + Oxygen <=> all-trans-Neurosporene + 2 H2O + Acceptor R04799 all-trans-zeta-Carotene + 2 Oxygen + 2 Reduced acceptor <=> Lycopene + 4 H2O + 2 Acceptor R04800 neurosporene,hydrogen-donor:oxygen oxidoreductase; all-trans-Neurosporene + Reduced acceptor + Oxygen <=> Lycopene + Acceptor + 2 H2O R04801 carotenoid beta-end group lyase (decyclizing); all-trans-Neurosporene <=> beta-Zeacarotene R04803 beta-Zeacarotene + Oxygen + Reduced acceptor <=> gamma-Carotene + 2 H2O + Acceptor R04804 delta8,24-cholestadien-3beta-ol delta7-delta8-isomerase; Zymosterol <=> 5alpha-Cholesta-7,24-dien-3beta-ol R04805 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + NADH + H+ R04806 3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin R04807 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane + H2O + 2 Oxidized adrenal ferredoxin R04808 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 5beta-Cyprinolsulfate R04809 (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA-forming]; (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + H2O <=> (24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA R04810 (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA:NAD+ oxidoreductase; (24R,25R)-3alpha,7alpha,24-Trihydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+ R04811 propanoyl-CoA:acetyl-CoA C-acyltransferase; 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA; C-acyltransferase; Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA R04812 (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA:NAD+ oxidoreductase; (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + NAD+ <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA + NADH + H+ R04813 (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming]; (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + H2O R04817 7alpha-hydroxy-5beta-cholestan-3-one:NADP+ delta4-oxidoreductase; 7alpha-Hydroxy-5beta-cholestan-3-one + NADP+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+ R04818 3alpha,7alpha-dihydroxy-5beta-cholestane:NAD+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+ R04819 3alpha,7alpha-dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+ R04823 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one:NADP+ delta4-oxidoreductase; 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADP+ <=> 4-Cholesten-7alpha,12alpha-diol-3-one + NADPH + H+ R04824 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane:NAD+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NAD+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADH + H+ R04825 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + NADP+ <=> 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one + NADPH + H+ R04826 7alpha-hydroxycholest-4-en-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating); 7alpha-Hydroxycholest-4-en-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Cholesten-7alpha,12alpha-diol-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O R04827 3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase; 4-Cholesten-7alpha,12alpha-diol-3-one + Reduced acceptor <=> 7alpha,12alpha-Dihydroxy-5alpha-cholestan-3-one + Acceptor R04829 urocortisone:NAD+ oxidoreductase (B-specific); Tetrahydrocortisone + NAD+ <=> 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADH + H+ R04830 urocortisone:NADP+ oxidoreductase (B-specific); Tetrahydrocortisone + NADP+ <=> 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+ R04831 cortolone:NAD+ oxidoreductase; Cortolone + NAD+ <=> Tetrahydrocortisone + NADH + H+ R04832 urocortisol:NAD+ oxidoreductase (B-specific); Urocortisol + NAD+ <=> Dihydrocortisol + NADH + H+ R04833 urocortisol:NADP+ oxidoreductase (B-specific); Urocortisol + NADP+ <=> Dihydrocortisol + NADPH + H+ R04834 cortol:NAD+ oxidoreductase; Cortol + NAD+ <=> Urocortisol + NADH + H+ R04835 3alpha,11beta,21-trihydroxy-20-oxo-5beta-pregnan-18-al:NAD+ oxidoreductase (B-specific); 3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NAD+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADH + H+ R04836 3alpha,11beta,21-trihydroxy-20-oxo-5beta-pregnan-18-al:NADP+ oxidoreductase (B-specific); 3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+ R04837 tetrahydrocorticosterone:NAD+ oxidoreductase (B-specific); Tetrahydrocorticosterone + NAD+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADH + H+ R04838 tetrahydrocorticosterone:NADP+ oxidoreductase (B-specific); Tetrahydrocorticosterone + NADP+ <=> 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione + NADPH + H+ R04840 tetrahydrocorticosterone:NADP+ 11-oxidoreductase; Tetrahydrocorticosterone + NADP+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADPH + H+ R04842 3alpha,21-dihydroxy-5beta-pregnane-11,20-dione:NAD+ oxidoreductase (B-specific); 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NAD+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADH + H+ R04843 3alpha,21-dihydroxy-5beta-pregnane-11,20-dione:NADP+ oxidoreductase (B-specific); 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADP+ <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+ R04844 3alpha,20alpha,21-trihydroxy-5beta-pregnane-11-one:NAD+ oxidoreductase; 3alpha,20alpha,21-Trihydroxy-5beta-pregnan-11-one + NAD+ <=> 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione + NADH + H+ R04845 3alpha-hydroxy-5beta-pregnane-20-one:NAD+ oxidoreductase (B-specific); Pregnanolone + NAD+ <=> 5beta-Pregnane-3,20-dione + NADH + H+ R04846 3alpha-hydroxy-5beta-pregnane-20-one:NADP+ oxidoreductase (B-specific); Pregnanolone + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+ R04847 pregnanediol:NAD+ oxidoreductase; Pregnanediol + NAD+ <=> Pregnanolone + NADH + H+ R04849 11-deoxycortisol delta5-delat4-isomerase; 17alpha,21-dihydroxypregnenolone:NAD+ 3-oxidoreductase; 11-Deoxycortisol + H+ + NADH <=> 17alpha,21-Dihydroxypregnenolone + NAD+ R04850 17alpha,21-dihydroxypregnenolone:oxygen oxidoreductase (11-hydroxylating); 17alpha,21-Dihydroxypregnenolone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta,17alpha,21-Trihydroxypregnenolone + 2 Oxidized ferredoxin + H2O R04852 11beta-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); 21-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O <=> 11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen R04853 20alpha-hydroxycholesterol,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); 20alpha-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha,20alpha-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R04854 20alpha-hydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving); 20alpha-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin R04855 22beta-hydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving); 22(R)-Hydroxycholesterol + Oxygen + 2 Reduced adrenal ferredoxin + 2 H+ <=> 20alpha,22beta-Dihydroxycholesterol + H2O + 2 Oxidized adrenal ferredoxin R04856 sulfatide sulfohydrolase; cerebroside-3-sulfate 3-sulfohydrolase; Sulfatide + H2O <=> Galactosylceramide + Sulfate R04857 5-Ureido-4-imidazole carboxylate + H2O <=> 5-Amino-4-imidazole carboxylate + Ammonia + CO2 R04858 S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase; S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + 5-Methylcytosine in DNA R04859 O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming); O3-acetyl-L-serine acetate-lyase (thiosulfate-reducing, L-cysteine-forming); O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate R04860 S-Glutathionyl-L-cysteine + Sulfate <=> S-Sulfo-L-cysteine + Glutathione R04861 3-Sulfinylpyruvate + H2O <=> Sulfite + Pyruvate R04862 (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating); Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+ R04863 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase; L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP R04864 2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase; Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine R04866 S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase; S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine R04867 S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase; S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine R04868 acyl-CoA:isopenicillin N N-acyltransferase; Isopenicillin N + Phenylacetyl-CoA + H2O <=> Penicillin G + L-2-Aminoadipate + CoA R04869 Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O R04870 L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting); L-2-Aminoadipate + L-Valine + L-Cysteine + 3 ATP + H2O <=> delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + 3 AMP + 3 Diphosphate R04872 delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + Oxygen <=> Isopenicillin N + 2 H2O R04874 Imidazol-5-yl-pyruvate <=> Imidazole-4-acetaldehyde + CO2 R04875 Hydantoin-5-propionate + H2O <=> N-Carbamyl-L-glutamate R04876 Imidazol-5-yl-pyruvate + NADH + H+ <=> Imidazole lactate + NAD+ R04877 Ergothioneine <=> Thiourocanic acid + Trimethylamine R04878 Ergothioneine <=> Hercynine R04879 Formylisoglutamine + H2O <=> Isoglutamine R04880 3,4-dihydroxyphenylethyleneglycol:NAD+ oxidoreductase; 3,4-Dihydroxyphenylethyleneglycol + NAD+ <=> 3,4-Dihydroxymandelaldehyde + NADH + H+ R04881 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + 3,4-Dihydroxyphenylethyleneglycol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxyphenylethyleneglycol R04882 3,4-dihydroxymandelaldehyde:NAD+ oxidoreductase; 3,4-Dihydroxymandelaldehyde + NAD+ + H2O <=> 3,4-Dihydroxymandelate + NADH + H+ R04883 3,4-dihydroxymandelaldehyde:NADP+ oxidoreductase; 3,4-Dihydroxymandelaldehyde + NADP+ + H2O <=> 3,4-Dihydroxymandelate + NADPH + H+ R04884 5,6-dihydroxyindole:oxygen oxidoreductase; 2 5,6-Dihydroxyindole + Oxygen <=> 2 Indole-5,6-quinone + 2 H2O R04885 5,6-Dihydroxyindole + CO2 <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole R04886 Indole-5,6-quinone + Oxygen <=> Eumelanin + H2O R04887 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + 3,4-Dihydroxymandelate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxymandelate R04888 3-methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase; 3-Methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O <=> Homovanillate + NADH + H+ R04889 3-methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase; 3-Methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> Homovanillate + NADPH + H+ R04890 3-methoxytyramine:oxygen oxidoreductase (deaminating) (copper-containing); 3-Methoxytyramine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylacetaldehyde + Hydrogen peroxide + Ammonia R04891 3-methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase; 3-Methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADH + H+ R04892 3-methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase; 3-Methoxy-4-hydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADPH + H+ R04893 L-normetanephrine:oxygen oxidoreductase (deaminating) (copper-containing); L-Normetanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Ammonia + Hydrogen peroxide R04894 L-metanephrine:oxygen oxidoreductase (deaminating) (flavin-containing); L-Metanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Hydrogen peroxide + Methylamine R04895 2-Hydroxyhepta-2,4-dienedioate + H2O <=> 4-Hydroxy-2-oxo-heptanedioate R04899 3-(2-Hydroxyphenyl)propanoate <=> Phenylpropanoate R04900 UDP-L-rhamnose:flavonol-3-O-D-glucoside L-rhamnosyltransferase; Isoquercitrin + UDP-L-rhamnose <=> Rutin + UDP R04901 (2S)-flavan-4-ol:NADP+ 4-oxidoreductase; cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase; Luteoforol + NADP+ <=> Eriodictyol + NADPH + H+ R04902 eriodictyol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Eriodictyol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pentahydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O R04903 5-hydroxyindoleacetaldehyde:NAD+ oxidoreductase; 5-Hydroxyindoleacetaldehyde + NAD+ + H2O <=> 5-Hydroxyindoleacetate + H+ + NADH R04904 5-hydroxyindoleacetaldehyde:oxygen oxidoreductase; 5-Hydroxyindoleacetaldehyde + Oxygen + H2O <=> 5-Hydroxyindoleacetate + Hydrogen peroxide R04905 S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase; S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate R04906 5-Hydroxyindoleacetate <=> 5-Hydroxyindoleacetylglycine R04907 3-hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing); 3-Hydroxykynurenamine + Oxygen <=> 4,8-Dihydroxyquinoline + Ammonia + Hydrogen peroxide R04908 5-hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing); 5-Hydroxykynurenamine + H2O + Oxygen <=> 4,6-Dihydroxyquinoline + Ammonia + Hydrogen peroxide + H2O R04909 5-hydroxykynurenamine decarboxy-lyase; 5-Hydroxykynurenamine + CO2 <=> 5-Hydroxykynurenine R04910 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate + NADPH + H+ <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate + NADP+ R04911 aryl-formylamine amidohydrolase; 5-Hydroxy-N-formylkynurenine + H2O <=> 5-Hydroxykynurenine + Formate R04913 5-hydroxykynurenine:2-oxoglutarate aminotransferase; 5-Hydroxykynurenine + 2-Oxo acid <=> 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate + Amino acid R04914 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate <=> 6-Hydroxykynurenate + H2O R04915 quinoline-3,4-diol 2,4-dioxygenase (carbon monoxide-forming); Quinoline-3,4-diol + Oxygen <=> Formylanthranilate + CO R04916 5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NAD+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADH + H+ R04917 5-(2'-Formylethyl)-4,6-dihydroxypicolinate + NADP+ + H2O <=> 5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate + NADPH + H+ R04918 5-(2'-Formylethyl)-4,6-dihydroxypicolinate + CO2 <=> 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate R04919 3-hydroxypropionyl-CoA:NADP+ oxidoreductase; 3-Hydroxypropionyl-CoA + NADP+ <=> 3-Oxopropionyl-CoA + NADPH + H+ R04920 CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase; CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate R04921 CMP-2-aminoethylphosphonate + N-Acylsphingosine <=> Ceramide 2-aminoethylphosphonate + CMP R04922 CMP-N-trimethyl-2-aminoethylphosphonate:1,2-diacylglycerol (N-trimethyl-2-aminoethylphosphonyl)transferase; CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate R04923 Diacylglyceryl-2-aminoethylphosphonate <=> Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate R04924 (2-Amino-1-hydroxyethyl)phosphonate <=> Lipophosphonoglycan R04925 N-Monomethyl-2-aminoethylphosphonate <=> N-Dimethyl-2-aminoethylphosphonate R04927 AMP,sulfite:(acceptor) oxidoreductase; 2 Ferricytochrome c + Selenite + AMP <=> 2 Ferrocytochrome c + Adenylylselenate R04928 ATP:adenylylsulfate 3'-phosphotransferase; ATP + Adenylylselenate <=> ADP + 3'-Phosphoadenylylselenate R04929 ATP:selenate adenylyltransferase; ATP + Selenate <=> Diphosphate + Adenylylselenate R04930 selenocystathionine lysteine-lyase (deaminating); L-Selenocystathionine + H2O <=> L-Selenocysteine + Ammonia + 2-Oxobutanoate R04931 S-adenosyl-L-methionine:thiol S-methyltransferase; L-Selenocysteine + S-Adenosyl-L-methionine <=> Se-Methyl-L-selenocysteine + S-Adenosyl-L-homocysteine R04932 2 L-Selenocysteine <=> Selenocystine R04933 L-Selenocysteine <=> Selenocysteine seleninic acid R04934 L-Selenocysteine <=> Se-Propenylselenocysteine Se-oxide R04935 (5-L-glutamyl)-peptide:Se-methylselenocysteine 5-glutamyltransferase; (5-L-Glutamyl)-peptide + Se-Methyl-L-selenocysteine <=> Peptide + gamma-Glutamyl-Se-methylselenocysteine R04937 Pentosan + H2O <=> Pentosan + D-Xylose R04938 Pentosan + H2O <=> Pentosan + L-Arabinose R04939 R + Se-Adenosylselenomethionine <=> CH3-R + Se-Adenosyl-L-selenohomocysteine R04940 3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+ R04941 selenocystathionine L-homocysteine-lyase (deaminating); L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate R04942 L-serine hydro-lyase (adding homocysteine); L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O R04943 2 Selenohomocysteine <=> Selenohomocystine R04944 O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine); O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate R04945 O-acetylhomoserine succinate-lyase (adding cysteine); O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate R04946 O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine); O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate R04947 N-Hydroxy-amino acid + Acceptor <=> 2-Oxoacid oxime + Reduced acceptor R04948 UDPglucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase; UDP-glucose + Cyanohydrin <=> Cyanoglycoside + UDP R04949 cyanoglycoside glucohydrolase; Cyanoglycoside + H2O <=> Cyanohydrin + D-Glucose R04950 acetyl-CoA:S-substituted L-cysteine N-acetyltransferase; Acetyl-CoA + S-Substituted L-cysteine <=> CoA + S-Substituted N-acetyl-L-cysteine R04951 R-S-Cysteinylglycine + H2O <=> S-Substituted L-cysteine + Glycine R04952 butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexanoyl-[acp] + CO2 + Acyl-carrier protein R04953 (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+ R04954 (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] <=> trans-Hex-2-enoyl-[acp] + H2O R04955 hexanoyl-[acp]:NAD+ trans-2-oxidoreductase; Hexanoyl-[acp] + NAD+ <=> trans-Hex-2-enoyl-[acp] + NADH + H+ R04956 hexanoyl-[acp]:NADP+ trans-2-oxidoreductase; Hexanoyl-[acp] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H+ R04957 hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxooctanoyl-[acp] + CO2 + Acyl-carrier protein R04958 octanoyl-[acp]:NAD+ trans-2-oxidoreductase; Octanoyl-[acp] + NAD+ <=> trans-Oct-2-enoyl-[acp] + NADH + H+ R04959 octanoyl-[acp]:NADP+ trans-2-oxidoreductase; Octanoyl-[acp] + NADP+ <=> trans-Oct-2-enoyl-[acp] + NADPH + H+ R04960 octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CO2 + Acyl-carrier protein R04961 decanoyl-[acp]:NAD+ trans-2-oxidoreductase; Decanoyl-[acp] + NAD+ <=> trans-Dec-2-enoyl-[acp] + NADH + H+ R04962 decanoyl-[acp]:NADP+ trans-2-oxidoreductase; Decanoyl-[acp] + NADP+ <=> trans-Dec-2-enoyl-[acp] + NADPH + H+ R04963 decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp] + CO2 + Acyl-carrier protein R04964 (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase; (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+ R04965 (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] <=> trans-Dodec-2-enoyl-[acp] + H2O R04966 tetradecanoyl-[acp]:NAD+ trans-2-oxidoreductase; Tetradecanoyl-[acp] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+ R04967 tetradecanoyl-[acp]:NADP+ trans-2-oxidoreductase; Tetradecanoyl-[acp] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H+ R04968 tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating); Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexadecanoyl-[acp] + CO2 + Acyl-carrier protein R04969 hexadecanoyl-[acp]:NAD+ trans-2-oxidoreductase; Hexadecanoyl-[acp] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+ R04970 hexadecanoyl-[acp]:NADP+ trans-2-oxidoreductase; Hexadecanoyl-[acp] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+ R04971 Uroporphyrinogen I + Reduced acceptor <=> Uroporphyrin I + Acceptor + 6 H+ R04972 uroporphyrinogen I carboxy-lyase; Uroporphyrinogen I <=> Coproporphyrinogen I + 4 CO2 R04973 Coproporphyrinogen I + Acceptor <=> Coproporphyrin I + Reduced acceptor + 6 H+ R04975 Cobyrinate + 1-Aminopropan-2-ol + 6 Ammonia <=> Cobinamide + 7 H2O R04977 Myoglobin <=> Globin + Heme R04978 (3Z)-Phycocyanobilin <=> (3Z)-Phycoerythrobilin R04979 bilirubin beta-diglucuronide glucuronosohydrolase; Bilirubin beta-diglucuronide + 2 H2O + 3 Reduced acceptor <=> D-Urobilinogen + 2 D-Glucuronate + 3 Acceptor R04980 2-Hexaprenylphenol + Oxygen + NADPH <=> 2-Hexaprenyl-6-hydroxyphenol + NADP+ + H2O R04981 2-Hexaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Hexaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine R04985 4-hydroxy-3-polyprenylbenzoate carboxy-lyase; 2-Polyprenylphenol + CO2 <=> 4-Hydroxy-3-polyprenylbenzoate R04986 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; 3-Octaprenyl-4-hydroxybenzoate <=> 2-Octaprenylphenol + CO2 R04987 2-Octaprenylphenol + Oxygen + NADPH + H+ <=> 2-Octaprenyl-6-hydroxyphenol + NADP+ + H2O R04988 S-adenosyl-L-methionine:3-(all-trans-octaprenyl)benzene-1,2-diol 2-O-methyltransferase; 2-Octaprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Octaprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine R04994 S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinol C-methyltransferase; Demethylphylloquinol + S-Adenosyl-L-methionine <=> Phylloquinol + S-Adenosyl-L-homocysteine R04996 3-methylimidazole acetaldehyde:NAD+ oxidoreductase; Methylimidazole acetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic acid + NADH + H+ R04998 beta-D-glucosyl-2-coumarinate glucohydrolase; cis-beta-D-Glucosyl-2-hydroxycinnamate + H2O <=> cis-2-Hydroxycinnamate + D-Glucose R04999 cis-2-Hydroxycinnamate <=> Coumarin + H2O R05000 polyisopentenylpyrolinate:4-hydroxybenzoate nonaprenyltransferase; all-trans-Polyprenyl diphosphate + 4-Hydroxybenzoate <=> 4-Hydroxy-3-polyprenylbenzoate + Diphosphate R05001 2-Hydroxyphenylacetate <=> 2,6-Dihydroxyphenylacetate R05002 GDPmannose:glycolipid 1,3-alpha-D-mannosyltransferase; GDP-mannose + beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol <=> GDP + alpha-D-Mannosyl-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol R05030 beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol:L-glutamine amidoligase (ADP-forming); ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia <=> ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine R05032 UDP-N-acetyl-D-glucosamine:undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine 4-beta-N-acetylglucosaminlytransferase; Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP R05035 S-adenosyl-L-methionine:kaempferol 3-O-methyltransferase; S-adenosyl-L-methionine:3,5,7,4'-tetrahydroxyfavone 3-O-methyltransferase; S-Adenosyl-L-methionine + Kaempferol <=> S-Adenosyl-L-homocysteine + 3-Methoxyapigenin R05036 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; Cyanidin + Succinate + CO2 + 2 H2O <=> Leucocyanidin + 2-Oxoglutarate + Oxygen + H+ R05037 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; Delphinidin + Succinate + CO2 + 2 H2O <=> Leucodelphinidin + 2-Oxoglutarate + Oxygen + H+ R05038 leucodelphinidin:NADP+ 4-oxidoreductase; Leucodelphinidin + NADP+ <=> Dihydromyricetin + NADPH + H+ R05039 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Dihydromyricetin + Succinate + CO2 R05040 (3Z)-Phycocyanobilin + Acceptor <=> (3Z)-Phytochromobilin + Reduced acceptor + 2 H+ R05041 Bathorhodopsin <=> Lumirhodopsin R05043 all-trans-Dehydroretinal <=> 11-cis-Dehydroretinal R05044 all-trans-Dehydroretinal <=> Porphyropsin R05045 11-cis-Dehydroretinal <=> Porphyropsin R05046 formamidopyrimidine nucleoside triphosphate amidohydrolase; Formamidopyrimidine nucleoside triphosphate + H2O <=> 2,5-Diaminopyrimidine nucleoside triphosphate + Formate R05048 2,5-diaminopyrimidine nucleoside triphosphate mutase; 2,5-Diaminopyrimidine nucleoside triphosphate <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine R05049 N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase; N-Succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O <=> N-Succinyl-L-glutamate + NADH + H+ R05050 N4-acetylaminobutanal:NAD+ oxidoreductase; N4-Acetylaminobutanal + NAD+ + H2O <=> 4-Acetamidobutanoate + NADH + H+ R05051 L-erythro-4-hydroxyglutamate:NAD+ oxidoreductase; L-erythro-4-Hydroxyglutamate + NADH + H+ <=> L-4-Hydroxyglutamate semialdehyde + NAD+ + H2O R05052 L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase; L-erythro-4-Hydroxyglutamate + 2-Oxoglutarate <=> (4R)-4-Hydroxy-2-oxoglutarate + L-Glutamate R05053 D-aspartate:2-oxoglutarate aminotransferase; D-Aspartate + (4R)-4-Hydroxy-2-oxoglutarate <=> Oxaloacetate + L-erythro-4-Hydroxyglutamate R05055 Leukotriene D4 + H2O <=> Leukotriene E4 + Glycine R05056 Prostaglandin A2 <=> Prostaglandin C2 R05057 Prostaglandin B2 <=> Prostaglandin C2 R05058 Prostaglandin J2 <=> Delta-12-Prostaglandin J2 R05059 6-Keto-prostaglandin F1alpha + Acceptor <=> 6-Keto-prostaglandin E1 + Reduced acceptor R05060 Thromboxane B2 + Acceptor <=> 11-Dehydro-thromboxane B2 + Reduced acceptor R05061 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase; trans-Cinnamoyl beta-D-glucoside + Propane-1-ol <=> Propyl cinnamate + D-Glucose R05062 2-propyn-1-ol:cytochrome-c oxidoreductase; 2-Propyn-1-ol + 2 Ferricytochrome c <=> 2-Propynal + 2 Ferrocytochrome c + 2 H+ R05063 2-Propylmalate + CoA <=> 2-Oxopentanoic acid + Acetyl-CoA + H2O R05064 (S)-3-hydroxyisobutyryl-CoA hydrolase; (S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate R05066 3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase; (S)-3-Hydroxyisobutyrate + NAD+ <=> (S)-Methylmalonate semialdehyde + NADH + H+ R05068 (R)-2,3-dihydroxy-3-methylpentanoate:NADP+ oxidoreductase (isomerizing); (R)-2,3-Dihydroxy-3-methylpentanoate + NADP+ <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate + NADPH + H+ R05069 (S)-2-aceto-2-hydroxybutanoate:NADP+ oxidoreductase (isomerizing); (S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate R05070 (R)-2,3-dihydroxy-3-methylpentanoate hydro-lyase; (R)-2,3-Dihydroxy-3-methylpentanoate <=> (S)-3-Methyl-2-oxopentanoic acid + H2O R05071 (S)-2-acetolactate methylmutase; (S)-2-Acetolactate <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid R05072 thiosulfate:dithioerythritol sulfurtransferase; Thiosulfate + Dithioerythritol + H+ <=> Sulfite + Hydrogen sulfide + 4,5-cis-Dihydroxy-1,2-dithiacyclohexane R05074 CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase; 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> KDO2-lipid IVA + CMP R05075 tetradecanoyl-[acyl-carrier protein]:dodecanoyl-KDO2-lipid IV(A) O-tetradecanoyltransferase; Tetradecanoyl-[acp] + Lauroyl-KDO2-lipid IV(A) <=> KDO2-lipid A + Acyl-carrier protein R05076 (2R,3S)-2-methylmalyl-CoA hydro-lyase (2-methylfumaryl-CoA-forming); L-erythro-3-Methylmalyl-CoA <=> 2-Methylfumaryl-CoA + H2O R05077 Parapyruvate + Ammonia <=> 4-Hydroxy-4-methylglutamate + H2O R05078 Parapyruvate <=> 4-Methylene-2-oxoglutarate + H2O R05079 4-Methylene-2-oxoglutarate + Ammonia <=> 4-Methyl-L-glutamate + H2O R05080 Trigalactosyl-diacylglycerol + UDP <=> Digalactosyl-diacylglycerol + UDP-alpha-D-galactose R05081 phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase; Phosphatidylglycerol + Diglucosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid R05083 UDP-glucose:4-hydroxyphenylethanol 1-O-beta-D-glucosyltransferase; 4-Hydroxyphenylethanol + UDP-glucose <=> Salidroside + UDP R05084 isopyridoxal:NAD+ oxidoreductase (5-pyridoxolactone-forming); Isopyridoxal + NAD+ <=> 5-Pyridoxolactone + NADH + H+ R05085 O-phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase; O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate R05086 O-phospho-4-hydroxy-L-threonine phospho-lyase (adding water); O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate R05087 4-Hydroxy-L-threonine <=> 3-Aminopropane-1,2-diol + CO2 R05088 Dimethylallyltryptophan <=> Elymoclavine R05089 Iridodial <=> Iridotrial R05090 Iridotrial <=> 7-Deoxyloganetin R05092 ent-copalyl-diphosphate diphosphate-lyase; ent-Copalyl diphosphate <=> ent-Kaurene + Diphosphate R05097 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A53 + 2-Oxoglutarate + Oxygen <=> Gibberellin A44 diacid + Succinate + CO2 R05098 6-Hydroxyhexan-6-olide <=> Adipate semialdehyde R05099 6-oxohexanoate:NADP+ oxidoreductase; Adipate semialdehyde + NADP+ + H2O <=> Adipate + NADPH + H+ R05100 cyclohexane-1,2-dione acylhydrolase (decyclizing); Adipate semialdehyde <=> Cyclohexane-1,2-dione + H2O R05102 NADPH:cytochrome-P-450 oxidoreductase; Cytochrome P-450 oxidized form + NADPH <=> Cytochrome P-450 reduced form + NADP+ + H+ R05105 3'-phosphoadenylylsulfate:digalactosylceramide 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Digalactosylceramide <=> Adenosine 3',5'-bisphosphate + Digalactosylceramide sulfate R05106 Ceramidepentasaccharide + GDP-L-fucose <=> Type A glycolipid + GDP R05107 Gal-alpha1->3(Fuc-alpha1->2)Gal-beta1->3GlcNAc-beta1->3LacCer + UDP <=> Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-alpha-D-galactose R05108 Fuc-alpha1->2Gal-beta1->3GlcNAc-beta1->3Gal-beta1->4Glc-beta1-1'Cer + UDP-N-acetyl-D-galactosamine <=> Type A glycolipid + UDP R05109 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2 R05110 UDP-alpha-D-galactose + GD2 <=> UDP + GD1b R05111 UDP-alpha-D-galactose + GA2 <=> UDP + GA1 R05112 Gal-beta1->3GalNAc-beta1->4Gal-beta1->4Glc-beta1->1'Cer (GA1) galactohydrolase; GA1 + H2O <=> GA2 + D-Galactose R05113 CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1 R05114 CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1 R05115 acylneuraminyl hydrolase; GT1b + N-Acetylneuraminate <=> GQ1 + H2O R05116 CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b R05117 GT1b + H2O <=> GD1b + N-Acetylneuraminate R05118 Poly-beta-hydroxybutyrate + H2O <=> Poly[(R)-3-hydroxybutanoate]x + (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate R05119 3-Butyn-1-al + NAD+ + H2O <=> 3-Butynoate + NADH + H+ R05120 3-Butyn-1-al + PQQ + H2O <=> 3-Butynoate + PQQH2 R05121 3-Butyn-1-al + PQQH2 <=> 3-Butyn-1-ol + PQQ R05122 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine + 2 S-Adenosyl-L-methionine <=> 6-(3'-Triphosphoryl-1'-methylglyceryl)-7-methyl-7,8-dihydrobiopterin + 2 S-Adenosyl-L-homocysteine + H2O R05123 S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase; S-Adenosyl-L-methionine + (S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (S)-Coclaurine R05124 codeine:NADP+ oxidoreductase; Codeine + NADP+ <=> Codeinone + NADPH + H+ R05125 neopinone Delta8-Delta7-isomerase; Codeinone <=> Neopinone R05126 thebaine,2-oxoglutarate:oxygen oxidoreductase (6-O-demethylating); Thebaine + 2-Oxoglutarate + Oxygen <=> Neopinone + Formaldehyde + Succinate + CO2 R05127 thebaine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating); Thebaine + 2-Oxoglutarate + Oxygen <=> Oripavine + Formaldehyde + Succinate + CO2 R05128 Anabasine + CO2 <=> Piperideine + Nicotinate R05129 Piperideine + Acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2 R05130 Piperideine + Pelletierine <=> L-(+)-Anaferine R05131 Pelletierine <=> N-Methylpelletierine R05132 protein-N(pi)-phosphohistidine:arbutin 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Arbutin <=> Protein histidine + Arbutin 6-phosphate R05133 arbutin 6-phosphate glucohydrolase; Arbutin 6-phosphate + H2O <=> Hydroquinone + beta-D-Glucose 6-phosphate R05134 salicin 6-phosphate glucohydrolase; Salicin 6-phosphate + H2O <=> Salicyl alcohol + beta-D-Glucose 6-phosphate R05135 2',3'-cyclic GMP 3'-nucleotidohydrolase; 2',3'-Cyclic GMP + H2O <=> Guanosine 3'-phosphate R05136 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase; Salicylaldehyde + Pyruvate <=> trans-o-Hydroxybenzylidenepyruvate + H2O R05137 2-hydroxy-2H-chromene-2-carboxylate---(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate isomerase; trans-o-Hydroxybenzylidenepyruvate <=> 2-Hydroxychromene-2-carboxylate R05138 2-hydroxy-6-oxohepta-2,4-dienoate acetylhydrolase; 2-Hydroxy-2,4-pentadienoate + Acetate <=> 2-Hydroxy-6-keto-2,4-heptadienoate + H2O R05140 sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase; D-Glucose + Levan <=> Sucrose + Levan R05141 1,4-beta-D-glucan glucohydrolase; Celloheptaose + H2O <=> Cellohexaose + D-Glucose R05142 1,4-beta-D-glucan glucohydrolase; Cellohexaose + H2O <=> Cellopentaose + D-Glucose R05144 peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing); Gla protein + Vitamin K1 epoxide + H2O <=> Gla protein precursor + Phylloquinol + CO2 + Oxygen R05145 biotinyl-5'-AMP:apo-[carboxylase] ligase (AMP-forming); Biotinyl-5'-AMP + Apo-[carboxylase] <=> AMP + Holo-[carboxylase] R05146 dodecanoyl-[acyl-carrier protein]:KDO2-lipid-IVA O-dodecanoyltransferase; Dodecanoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> Lauroyl-KDO2-lipid IV(A) + Acyl-carrier protein R05148 benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating); Terephthalate + Oxygen + NADH + H+ <=> (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ R05149 S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating); 2 S-Adenosyl-L-methionine + Precorrin 6Y <=> 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 R05150 precorrin-6Y:NADP+ oxidoreductase; Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+ R05151 isoquinoline:acceptor 1-oxidoreductase (hydroxylating); Isoquinoline + Acceptor + H2O <=> Isocarbostyril + Reduced acceptor R05152 quinoline:acceptor 2-oxidoreductase (hydroxylating); Quinoline + Acceptor + H2O <=> 2(1H)-Quinolinone + Reduced acceptor R05153 6-chlorobenzene-1,2,4-triol:oxygen 7S,8S-oxidoreductase; 6-Chlorobenzene-1,2,4-triol + Oxygen <=> 2-Chloromaleylacetate R05154 quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating); 4-Hydroxyquinoline + Oxygen + NADH + H+ <=> Quinoline-3,4-diol + NAD+ + H2O R05155 2-methylquinoline-3,4-diol 2,4-dioxygenase (carbon monoxide-forming); 2-Methylquinoline-3,4-diol + Oxygen <=> N-Acetylanthranilate + CO R05156 2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming); 2-Aminobenzenesulfonate + Oxygen + NADH + H+ <=> 3-Sulfocatechol + Ammonia + NAD+ R05157 quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating); Quinolin-2-ol + Oxygen + NADH + H+ <=> 2,5,6-Trihydroxy-5,6-dihydroquinoline + NAD+ R05158 quinolin-2-ol,NADH:oxygen oxidoreductase (8-hydroxylating); Quinolin-2-ol + Oxygen + NADH + H+ <=> Quinolin-2,8-diol + NAD+ + H2O R05162 S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase; S-Adenosyl-L-methionine + (R,S)-Norcoclaurine <=> S-Adenosyl-L-homocysteine + (R,S)-Coclaurine R05163 4-hydroxycinnamoyl-CoA:anthocyanidin 3,5-di-O-beta-D-glucoside 5-O-glucoside-6'''-O-4-hydroxycinnamoyltransferase; p-Coumaroyl-CoA + Anthocyanidin-3,5-diglucoside <=> CoA + Anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside R05164 UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase; UDP-glucose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + alpha-Kojibiosyldiacylglycerol R05165 1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating); 1-Carboxyvinyl carboxyphosphonate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2 R05166 lacto-N-tetraose lacto-N-biosylhydrolase; Lacto-N-tetraose + H2O <=> Lacto-N-biose + Lactose R05167 phthalyl-amide amidohydrolase; Phthalylamide + H2O <=> Phthalate + Amine R05168 N-acetyl-D-galactosamine 6-phosphate amidohydrolase; N-Acetyl-D-galactosamine 6-phosphate + H2O <=> D-Galactosamine 6-phosphate + Acetate R05169 methylenediurea aminohydrolase; Methylenediurea + 2 H2O <=> N-(Hydroxymethyl)urea + CO2 + 2 Ammonia R05170 methylenediurea aminohydrolase; Methylenediurea + H2O <=> N-(Carboxyaminomethyl)urea + Ammonia R05171 N-(carboxyaminomethyl)urea aminohydrolase; N-(Carboxyaminomethyl)urea <=> N-(Aminomethyl)urea + CO2 R05172 N-(aminomethyl)urea aminohydrolase; N-(Aminomethyl)urea + H2O <=> N-(Hydroxymethyl)urea + Ammonia R05173 2-Aryl-2-methylmalonate carboxy-lyase; 2-Aryl-2-methylmalonate <=> 2-Arylpropionate + CO2 R05174 16-alpha-hydroxypregnenolone hydro-lyase; 16alpha-Hydroxypregnenolone <=> 16,17-Didehydropregnenolone + H2O R05175 [protein]-L-serine epimerase; omega-Agatoxin IVC <=> omega-Agatoxin IVB R05176 ADP-D-glycero-D-manno-heptose 6-epimerase; ADP-D-glycero-beta-D-manno-heptose <=> ADP-L-glycero-beta-D-manno-heptose R05177 precorrin 8X 11,12-methylmutase; Precorrin 8X <=> Hydrogenobyrinate R05179 S-adenosyl-L-methionine:[RbcL]-L-lysine N6-methyltransferase; 3 S-Adenosyl-L-methionine + [Ribulose-1,5-bisphosphate carboxylase]-L-lysine + H+ <=> 3 S-Adenosyl-L-homocysteine + [Ribulose-1,5-bisphosphate carboxylase]-N6,N6,N6-trimethyl-L-lysine R05180 S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 R05181 S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase; S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5 R05182 [methionine synthase]-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase; 2 S-Adenosyl-L-methionine + 2 [Methionine synthase]-cob(II)alamin + NADPH + H+ <=> 2 [Methionine synthase]-methylcob(III)alamin + 2 S-Adenosyl-L-homocysteine + NADP+ R05183 quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating); 4-Quinolinecarboxylic acid + Acceptor + H2O <=> 2-Oxo-1,2-dihydroquinoline-4-carboxylate + Reduced acceptor R05185 reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + Nitrogen + 8 Reduced ferredoxin + 8 H+ + 16 H2O <=> 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin + 2 Ammonia + Hydrogen R05186 reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + Nitrogen + 4 Reduced flavodoxin + 16 H2O <=> 16 Orthophosphate + 16 ADP + 4 Oxidized flavodoxin + 2 Ammonia + Hydrogen R05188 acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing); Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ <=> Long-chain fatty acid + n CO2 + 2n NADP+ + (n+1) CoA + n H2O R05189 acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing); Acyl-CoA + n Methylmalonyl-CoA + 2n NADPH + 2n H+ + Acyl-carrier protein <=> Multi-methyl-branched acyl-[acp] + (n+1) CoA + n CO2 + 2n NADP+ + n H2O R05190 acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing); Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 4n H+ <=> Long-chain acyl-CoA + n CoA + n CO2 + 2n NADP+ + n H2O R05191 UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase; n UDP-D-galacturonate <=> n UDP + Pectin R05193 n ATP + Calmodulin + n Ubiquitin <=> n AMP + n Diphosphate + (Ubiquitin)n-calmodulin R05196 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase; Amylose + n D-Glucose <=> n Maltose R05197 10-formyltetrahydropteroyldiglutamate:L-glutamate gamma-ligase (ADP-forming); n-1 ATP + (6R)-10-Formyltetrahydropteroyldiglutamate + n-1 L-Glutamate <=> n-1 ADP + n-1 Orthophosphate + 10-Formyltetrahydrofolylpolyglutamate R05198 ethanol:cytochrome c oxidoreductase; Ethanol + 2 Ferricytochrome c <=> 2 Ferrocytochrome c + Acetaldehyde + 2 H+ R05199 protein-N(pi)-phosphohistidine:N-acetyl-D-glucosamine 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + N-Acetyl-D-glucosamine <=> Protein histidine + N-Acetyl-D-glucosamine 6-phosphate R05202 ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase; Phytic acid + ADP <=> 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate + ATP R05207 Leukotriene E4 + L-Glutamate <=> Leukotriene F4 + H2O R05209 diacylglycerol acylhydrolase; Diacylglycerol + H2O <=> 1-Acylglycerol + Carboxylate R05210 (S)-coclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling); (S)-Coclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Norberbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R05211 S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinolie N- methyltransferase; S-Adenosyl-L-methionine + (S)-Norreticuline <=> S-Adenosyl-L-homocysteine + (S)-Reticuline R05212 S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase; S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Norreticuline R05213 S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase; S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-Nororientaline R05214 S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase; S-Adenosyl-L-methionine + (S)-Norlaudanosoline <=> S-Adenosyl-L-homocysteine + (S)-6-O-Methylnorlaudanosoline R05215 (R)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling); 2 (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Guattegaumerine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R05216 S-adenosyl-L-methionine:(R)-norreticuline N- methyltransferase; S-Adenosyl-L-methionine + (R)-Norreticuline <=> S-Adenosyl-L-homocysteine + (R)-Reticuline R05217 precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating); Precorrin 3A + Oxygen + NADH + H+ <=> Precorrin 3B + NAD+ + H2O R05218 cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase; 2 Cob(II)yrinate a,c diamide + Reduced FMN <=> 2 Cob(I)yrinate a,c diamide + FMN + 2 H+ R05219 Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine <=> Precorrin 5 + S-Adenosyl-L-methionine + H2O R05220 ATP:cob(I)yrinic acid-a,c-diamide Cobeta-adenosyltransferase; Cob(I)yrinate a,c diamide + ATP <=> Adenosyl cobyrinate a,c diamide + Triphosphate R05221 Adenosyl cobinamide + ATP <=> Adenosyl cobinamide phosphate + ADP R05222 GTP:adenosylcobinamide-phosphate guanylyltransferase; Adenosyl cobinamide phosphate + GTP <=> Adenosine-GDP-cobinamide + Diphosphate R05223 Cobamide coenzyme + GMP <=> Adenosine-GDP-cobinamide + alpha-Ribazole R05224 Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP R05225 Adenosyl cobyrinate a,c diamide + 4 L-Glutamine + 4 ATP + 4 H2O <=> Adenosyl cobyrinate hexaamide + 4 L-Glutamate + 4 Orthophosphate + 4 ADP R05226 adenosylcobinamide amidohydrolase; Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> Adenosyl cobinamide + H2O R05227 hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming); Hydrogenobyrinate a,c diamide + Cobalt ion + ATP + H2O <=> Cob(II)yrinate a,c diamide + Orthophosphate + ADP + H+ R05228 penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding); Deacetylcephalosporin C + H2O + 2 Succinate + 2 CO2 <=> Penicillin N + 2 2-Oxoglutarate + 2 Oxygen R05229 Deacetylcephalosporin C + Succinate + CO2 <=> Deacetoxycephalosporin C + 2-Oxoglutarate + Oxygen R05230 carbamoyl-phosphate:deacetylcephalosporin C carbamoyltransferase; Deacetylcephalosporin C + Carbamoyl phosphate <=> O-Carbamoyl-deacetylcephalosporin C + Orthophosphate R05231 6-hydroxyhexanoate:NADP+ oxidoreductase; 6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H+ R05232 p-cumic alcohol:NAD+ oxidoreductase; p-Cumic alcohol + NAD+ <=> 4-Isopropylbenzaldehyde + NADH + H+ R05233 trans-3-chloro-2-propene-1-ol:NAD+ oxidoreductase; trans-3-Chloro-2-propene-1-ol + NAD+ <=> trans-3-Chloroallyl aldehyde + NADH + H+ R05234 cis-3-chloro-2-propene-1-ol:NAD+ oxidoreductase; cis-3-Chloro-2-propene-1-ol + NAD+ <=> cis-3-Chloroallyl aldehyde + NADH + H+ R05235 p-cumic aldehyde:NAD+ oxidoreductase; 4-Isopropylbenzaldehyde + NAD+ + H2O <=> p-Cumate + NADH + H+ R05236 4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase; cis,cis-4-Hydroxymuconic semialdehyde + NAD+ + H2O <=> 2-Maleylacetate + NADH + H+ R05237 trans-3-Chloroallyl aldehyde + H2O <=> trans-3-Chloroacrylic acid + 2 H+ R05238 cis-3-Chloroallyl aldehyde + H2O <=> cis-3-Chloroacrylic acid + 2 H+ R05239 cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase; cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+ <=> Biphenyl-2,3-diol + NADH + H+ R05240 cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase; cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+ <=> 2,3-Dihydroxy-p-cumate + NADH + H+ R05241 cis-2,3-dihydro-2,3-dihydroxy-4'-chlorobiphenyl:NAD+ oxidoreductase; cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+ <=> 2,3-Dihydroxy-4'-chlorobiphenyl + NADH + H+ R05243 2,5-dichloro-2,5-cyclohexadiene-1,4-diol:NAD+ oxidoreductase; 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ <=> 2,5-Dichlorohydroquinone + NADH + H+ R05244 NADPH:p-benzoquinone oxidoreductase; p-Benzoquinone + NADPH + H+ <=> Hydroquinone + NADP+ R05245 2,3-dihydroxy-4'-chlorobiphenyl:oxygen 1,2-oxidoreductase (decyclizing); 2,3-Dihydroxy-4'-chlorobiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate R05246 Hydroquinone + Oxygen <=> cis,cis-4-Hydroxymuconic semialdehyde R05247 4-isopropylbenzoate:oxygen 2,3-oxidoreductase; p-Cumate + Oxygen + NADH + H+ <=> cis-2,3-Dihydroxy-2,3-dihydro-p-cumate + NAD+ R05248 2,3-Dihydroxy-p-cumate + Oxygen <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate R05249 resorcinol,NADPH:oxogen oxidoreductase (2-hydroxylating); Resorcinol + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + NADP+ + H2O R05250 1,2,3-Trihydroxybenzene + NADP+ + H2O <=> Resorcinol + Oxygen + NADPH + H+ R05251 2,2-Bis(4'-chlorophenyl)ethanol + H2O <=> Bis(4'-chlorophenyl)acetate + 4 H+ R05252 4-Chlorobenzoate <=> 4-Chlorobenzaldehyde + H2O R05255 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Reduced acceptor + 2 H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor R05256 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate R05257 2,3-Dihydroxy-1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + Oxygen <=> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate R05258 4-nitrophenol,NADPH:oxygen 4-oxidoreductase (4-hydroxylating, nitrite-forming); p-Benzoquinone + Nitrite + NADP+ + H2O <=> 4-Nitrophenol + Oxygen + NADPH + H+ R05259 parathion,NADPH---hemoprotein reductase:oxygen oxidoreductase (paraoxon-forming); Parathion + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Paraoxon + [Oxidized NADPH---hemoprotein reductase] + Sulfur + H2O R05260 DDT + Reduced acceptor + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + Acceptor R05261 biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating); 4-Chlorobiphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NAD+ R05262 4-Chlorobiphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl + NADP+ R05263 biphenyl,NADH2:oxygen oxidoreductase (2,3-hydroxylating); Biphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+ R05264 biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating); Biphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NADP+ R05265 4-Nitrocatechol + Oxygen + 3 H+ <=> Benzene-1,2,4-triol + Nitrite + H2O R05266 p-cymene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating); p-Cymene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> p-Cumic alcohol + 2 Oxidized ferredoxin + H2O R05267 Hydrochloric acid + Hydroquinone + Glutathione disulfide <=> Chlorohydroquinone + 2 Glutathione R05268 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + H+ <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl- R05269 2,5-Dichlorohydroquinone + 2 Glutathione <=> Chlorohydroquinone + Glutathione disulfide + Hydrochloric acid R05270 6-deoxyerythronolide-B,reduced ferredoxin:oxygen oxidoreductase; 6-Deoxyerythronolide B + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Erythronolide B + 2 Oxidized ferredoxin + H2O R05271 4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase; 4-Sulfobenzyl alcohol + NAD+ <=> 4-Sulfobenzaldehyde + NADH + H+ R05272 4-formylbenzenesulfonate:NAD+ oxidoreductase; 4-Sulfobenzaldehyde + NAD+ + H2O <=> 4-Sulfobenzoate + NADH + H+ R05273 4-hydroxy-3-methoxybenzoate:oxygen oxidoreductase; Vanillate + NAD+ + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Oxygen + NADH + H+ R05274 vanillate:oxygen oxidoreductase (demethylating); Vanillate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde R05275 cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase; cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ <=> 4,5-Dihydroxyphthalate + NADH + H+ R05276 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating); 4-Chlorobenzoyl-CoA + Hydrochloric acid + NADP+ <=> 2,4-Dichlorobenzoyl-CoA + NADPH + H+ R05277 4-Aminobenzenesulfonate + 4-Aminobenzoate <=> 4-Carboxy-4'-sulfoazobenzene + 4 H+ R05278 4-Sulfocatechol + Oxygen <=> 3-Sulfomuconate R05279 4-Aminobenzenesulfonate + Oxygen + 2 H+ <=> 4-Sulfocatechol + Ammonia R05280 3,4-Dihydroxybenzoate + Ammonia <=> 4-Aminobenzoate + Oxygen + 2 H+ R05281 Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Sulfobenzyl alcohol + NAD+ + H2O R05282 4-methylbenzyl alcohol:NAD+ oxidoreductase; 4-Methylbenzyl alcohol + NAD+ <=> p-Tolualdehyde + NADH + H+ R05283 6-hydroxyhexanoate:NAD+ oxidoreductase; 6-Hydroxyhexanoic acid + NAD+ <=> Adipate semialdehyde + NADH + H+ R05284 1,2-dichloroethane halidohydrolase; 1,2-Dichloroethane + H2O <=> 2-Chloroethanol + Hydrochloric acid R05285 2-chloroethanol:cytochrome c oxidoreductase; 2-Chloroethanol + 2 Ferricytochrome c <=> Chloroacetaldehyde + 2 Ferrocytochrome c + 2 H+ R05286 chloroacetaldehyde:NAD+ oxidoreductase; Chloroacetaldehyde + NAD+ + H2O <=> Chloroacetic acid + NADH + H+ R05287 chloroacetic acid halidohydrolase; Chloroacetic acid + H2O <=> Glycolate + Hydrochloric acid R05288 p-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating); p-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 4-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O R05289 p-methylbenzaldehyde:NADP+ oxidoreductase; p-Tolualdehyde + NADP+ + H2O <=> Toluate + NADPH + H+ R05290 Toluate + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+ R05291 Toluate + Oxygen + NADPH + H+ <=> cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ R05292 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating); cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+ <=> 4-Methylcatechol + CO2 + NADH + H+ R05293 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NADP+ oxidoreductase (decarboxylating); cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ <=> 4-Methylcatechol + CO2 + NADPH + H+ R05294 toluene-4-sulfonate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming); Toluene-4-sulfonate + Oxygen + NADH + H+ <=> 4-Methylcatechol + Sulfite + NAD+ R05295 4-methylcatechol:oxygen 2,3-oxidoreductase(decyclizing); 4-Methylcatechol + Oxygen <=> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde R05296 2-hydroxy-5-methyl-cis,cis-muconic semialdehyde formylhydrolase; 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + (4E)-2-Oxohexenoic acid R05297 (4E)-2-Oxohexenoic acid + H2O <=> 4-Hydroxy-2-oxohexanoic acid R05298 4-hydroxy-2-oxohexanoate pyruvate-lyase (propanal-forming); Propanal + Pyruvate <=> 4-Hydroxy-2-oxohexanoic acid R05299 4-methylcatechol:oxygen 1,2-oxidoreductase(decyclizing); 4-Methylcatechol + Oxygen <=> 3-Methyl-cis,cis-hexadienedioate R05300 4-methylmuconolactone lyase (decyclizing); 4-Methylmuconolactone <=> 3-Methyl-cis,cis-hexadienedioate R05301 penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding); Penicillin N + 2-Oxoglutarate + Oxygen <=> Deacetoxycephalosporin C + Succinate + CO2 + H2O R05302 O-Carbamoyl-deacetylcephalosporin C + 2-Oxoglutarate + Oxygen <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + Succinate + CO2 R05303 Cephamycin C + S-Adenosyl-L-homocysteine <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + S-Adenosyl-L-methionine R05304 Nucleoside + Deoxynucleoside 5'-phosphate <=> Deoxynucleoside + Nucleoside 3'-phosphate R05305 3-hydroxypimeloyl-CoA:NAD+ oxidoreductase; 3-Hydroxypimeloyl-CoA + NAD+ <=> 3-Oxopimeloyl-CoA + NADH + H+ R05307 formaldehyde:NAD+ oxidoreductase (mycothiol-formylating); Formaldehyde + Mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+ R05308 dihydrophloroglucinol:NADP+ oxidoreductase; Dihydrophloroglucinol + NADP+ <=> Phloroglucinol + NADPH + H+ R05309 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate:NAD+ oxidoreductase (decarboxylating); 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + CO2 + NADH + H+ R05310 cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase; cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene + NAD+ <=> 1,2-Dihydroxydibenzothiophene + NADH + H+ R05311 pimeloyl-CoA:NAD+ oxidoreductase; Pimeloyl-CoA + NAD+ <=> 6-Carboxyhex-2-enoyl-CoA + NADH + H+ R05312 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline:NAD+ oxidoreductase; 5,6-Dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ <=> 5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+ R05313 cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase; cis-1,2-Dihydro-3-ethylcatechol + NAD+ <=> 3-Ethylcatechol + NADH + H+ R05314 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating); 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ <=> 2,3-Dihydroxytoluene + NADH + CO2 + H+ R05315 (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase; (1S,3R,4S)-3,4-Dihydroxycyclohexane-1-carboxylate + NAD+ <=> (1S,4S)-4-Hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+ R05316 benzoyl-CoA:acceptor oxidoreductase; 4-Hydroxybenzoyl-CoA + Reduced ferredoxin <=> Benzoyl-CoA + Oxidized ferredoxin + H2O R05317 L-tryptophan:oxygen alpha,beta-oxidoreductase; L-Tryptophan + Oxygen <=> alpha,beta-Didehydrotryptophan + Hydrogen peroxide R05318 ferrocytochrome-c:Fe3+ oxidoreductase; Ferrocytochrome c + Fe3+ <=> Ferricytochrome c + Fe2+ R05320 taurine,2-oxoglutarate:O2 oxidoreductase (sulfite-forming); Taurine + 2-Oxoglutarate + Oxygen <=> Sulfite + Aminoacetaldehyde + Succinate + CO2 R05321 n-tetradecanoyl-CoA,NADPH2:O2 oxidoreductase [11-(E) desaturating]; Tetradecanoyl-CoA + NADH + Oxygen + H+ <=> (E)-11-Tetradecenoyl-CoA + NAD+ + 2 H2O R05322 n-tetradecanoyl-CoA,NADH:O2 oxidoreductase [11-(Z) desaturating]; Tetradecanoyl-CoA + NADH + Oxygen + H+ <=> (Z)-11-Tetradecenoyl-CoA + NAD+ + 2 H2O R05323 S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; S-Adenosyl-L-methionine + 3-O-Methylquercetin <=> S-Adenosyl-L-homocysteine + 3,7-Di-O-methylquercetin R05324 UDPglucose:cis-p-coumarate beta-D-glucosyltransferase; UDP-glucose + cis-p-Coumarate <=> 4'-O-beta-D-Glucosyl-cis-p-coumarate + UDP R05325 UDP-glucose:limonin glucosyltransferase; UDP-glucose + Limonin <=> Glucosyl-limonin + UDP R05326 beta-D-galactopyranosyl-(13)-N-acetyl-D-hexosamine:phosphate galactosyltransferase; Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine R05327 n UDP-N-acetyl-alpha-D-glucosamine + n UDP-glucuronate <=> Hyaluronate + 2n UDP R05328 ADP-alpha-D-glucose:sn-glycerol-3-phosphate 2-alpha-D-glucopyranosyltransferase; ADP-glucose + sn-Glycerol 3-phosphate <=> 2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + ADP R05329 spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming); [eIF5A-precursor]-lysine + Spermidine <=> [eIF5A-precursor]-deoxyhypusine + 1,3-Diaminopropane R05330 4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase; 4,8,12-Trimethyltridecanoyl-CoA + Propanoyl-CoA <=> 3-Oxopristanoyl-CoA + CoA R05331 isovaleryl-CoA:malonyl-CoA acyltransferase; 3-Methylbutanoyl-CoA + 3 Malonyl-CoA <=> 4 CoA + 3 CO2 + Phlorisovalerophenone R05332 acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase; Acetyl-CoA + alpha-D-Glucosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-glucosamine 1-phosphate R05333 phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase; Phospholipid + 1,2-Diacyl-sn-glycerol <=> Lysophospholipid + Triacylglycerol R05334 N-Methylputrescine + Oxygen + H2O <=> 4-Methylaminobutanal + Hydrogen peroxide + Ammonia R05335 4-Methylaminobutanal <=> 1-Methylpyrrolinium + H2O R05336 acetyl-CoA:4-hydroxybutanoate CoA-transferase; 4-Hydroxybutanoic acid + Acetyl-CoA <=> 4-Hydroxybutyryl-CoA + Acetate R05337 4-hydroxybutanoyl-CoA hydro-lyase; 4-Hydroxybutyryl-CoA <=> Vinylacetyl-CoA + H2O R05338 D-arabino-hex-3-ulose-6-phosphate formaldehyde-lyase (D-ribulose-5-phosphate-forming); D-Ribulose 5-phosphate + Formaldehyde <=> D-arabino-Hex-3-ulose 6-phosphate R05339 D-arabino-hex-3-ulose-6-phosphate isomerase; D-arabino-Hex-3-ulose 6-phosphate <=> D-Fructose 6-phosphate R05341 carotenoid beta-end group lyase (decyclizing); Lycopene <=> gamma-Carotene R05344 4-Chloroacetophenone <=> 4-Chlorobenzaldehyde + CO2 R05345 beta-carotene,donor:oxygen oxidoreductase (echinenone-forming); beta-Carotene + 2 Reduced acceptor + 2 Oxygen <=> Echinenone + 2 Acceptor + 3 H2O R05346 Parathion + 3 Reduced acceptor <=> Aminoparathion + 3 Acceptor + 2 H2O R05347 3-Methylbenzyl alcohol + NAD+ <=> 3-Methylbenzaldehyde + NADH + H+ R05348 2-Methylbenzyl alcohol + NAD+ <=> 2-Methylbenzaldehyde + NADH + H+ R05349 Fluoren-9-ol + NAD+ <=> Fluoren-9-one + NADH + H+ R05350 Fluoren-9-ol + NADP+ <=> Fluoren-9-one + NADPH + H+ R05351 Ethylene oxide + CoA + NAD+ <=> Acetyl-CoA + NADH + H+ R05352 (S)-1-phenylethanol:NAD+ oxidoreductase; (S)-1-Phenylethanol + NAD+ <=> Acetophenone + NADH + H+ R05353 2-hydroxy-5-methyl-cis,cis-muconic semialdehyde:NAD+ 6-oxidoreductase; 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + NAD+ + H2O <=> 2-Hydroxy-5-methyl-cis,cis-muconate + NADH + H+ R05354 styrene cis-glycol:NAD+ oxidoreductase; Styrene-cis-2,3-dihydrodiol + NAD+ <=> 3-Vinylcatechol + NADH + H+ R05355 2-Chloromaleylacetate + NADH <=> 2-Maleylacetate + NAD+ + Cl- R05356 2-hydroxy-cyclohexan-1-one amidohydrolase; epsilon-Caprolactam + H2O <=> 6-Aminohexanoate R05357 amidinoproclavaminate amidinohydrolase; Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea R05358 acrylonitrile aminohydrolase; Acrylonitrile + 2 H2O <=> Acrylic acid + Ammonia R05359 2-hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate benzoylhydrolase; 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate + H2O <=> 4-Chlorobenzoate + 2-Hydroxy-2,4-pentadienoate R05360 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H2O <=> Salicylate + 2-Hydroxy-2,4-pentadienoate R05361 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O <=> 2-Hydroxymuconate + Catechol R05362 2-hydroxy-6-oxoocta-2,4,7-trienoate formylhydrolase; 2-Hydroxy-6-oxoocta-2,4,7-trienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Acrylic acid R05363 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate + H2O <=> 2-(4'-Chlorophenyl)-3,3-dichloropropenoate + 2-Hydroxy-3-chloropenta-2,4-dienoate R05364 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate acylhydrolase; 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O <=> 2-Methylpropanoate + 2-Hydroxy-2,4-pentadienoate R05365 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate benzoylhydrolase; 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Anthranilate R05366 2-hydroxy-6-oxo-octa-2,4-dienoate acylhydrolase; 2-Hydroxy-6-oxo-octa-2,4-dienoate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Propanoate R05367 trans-1,3-dichloropropene chlorohydrolase; trans-1,3-Dichloropropene + H2O <=> trans-3-Chloro-2-propene-1-ol + Hydrochloric acid R05368 cis-1,3-dichloropropene chlorohydrolase; cis-1,3-Dichloropropene + H2O <=> cis-3-Chloro-2-propene-1-ol + Hydrochloric acid R05369 1,3,4,6-tetrachloro-1,4-cyclohexadiene chlorohydrolase; 1,3,4,6-Tetrachloro-1,4-cyclohexadiene + H2O <=> 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + Hydrochloric acid R05370 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric acid R05371 trans-3-chloroacrylic acid chlorohydrolase; trans-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate R05372 cis-3-chloroacrylic acid chlorohydrolase; cis-3-Chloroacrylic acid + H2O <=> Hydrochloric acid + 3-Oxopropanoate R05373 methylmalonyl-CoA carboxy-lyase; Methylmalonyl-CoA <=> Propanoyl-CoA + CO2 R05374 2-oxo-5-methyl-cis-muconate carboxy-lyase; 2-Oxo-5-methyl-cis-muconate <=> 2-Hydroxy-cis-hex-2,4-dienoate + CO2 R05375 4-hydroxyphthalate carboxy-lyase; 4-Hydroxyphthalate <=> 3-Hydroxybenzoate + CO2 R05376 Bis(4'-chlorophenyl)methane + CO2 <=> Bis(4'-chlorophenyl)acetate R05377 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate carboxy-lyase; 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate <=> 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate + CO2 R05378 2-deoxy-5-keto-D-gluconic acid 6-phosphate dihydroxyacetone phosphate-lyase; 2-Deoxy-5-keto-D-gluconic acid 6-phosphate <=> 3-Oxopropanoate + Glycerone phosphate R05379 acrylamide hydro-lyase; Acrylamide <=> Acrylonitrile + H2O R05380 acetaldehyde hydro-lyase; Acetaldehyde <=> Acetylene + H2O R05381 diethanolamine ethanolamine-lyase (acetaldehyde-forming); Ethanolamine + Acetaldehyde <=> Diethanolamine R05382 triethanolamine diethanolamine-lyase (acetaldehyde-forming); Triethanolamine <=> Diethanolamine + Acetaldehyde R05383 (hydroxyamino)benzene hydroxymutase; 2-Aminophenol <=> Hydroxylaminobenzene R05384 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethane chloride-lyase; TDE <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Hydrochloric acid R05385 1-chloro-2,2-bis(4'-chlorophenyl)ethane chloride-lyase; 1-Chloro-2,2-bis(4'-chlorophenyl)ethane <=> unsym-Bis(4'-chlorophenyl)ethylene + Hydrochloric acid R05386 gamma-hexachlorocyclohexane chloride-lyase; Lindane <=> gamma-Pentachlorocyclohexene + Hydrochloric acid R05387 gamma-pentachlorocyclohexene chloride-lyase; gamma-Pentachlorocyclohexene <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene + Hydrochloric acid R05388 5-chloro-1,2,4-trihydroxybenzene chloride-lyase; 5-Chloro-1,2,4-trihydroxybenzene <=> 2-Hydroxy-1,4-benzoquinone + Hydrochloric acid R05389 2-hydroxy-5-methyl-cis,cis-muconate 2-oxo-5-methyl-cis-muconate isomerase; 2-Hydroxy-5-methyl-cis,cis-muconate <=> 2-Oxo-5-methyl-cis-muconate R05390 3-Chloro-cis,cis-muconate <=> Protoanemonin + Hydrochloric acid + CO2 R05391 3-Chloro-cis,cis-muconate <=> cis-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid R05392 trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid <=> 2,5-Dichloro-cis,cis-muconate R05393 2,4-Dichloro-cis,cis-muconate <=> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid R05394 4-sulfolactone lyase; 3-Sulfomuconate <=> 4-Sulfolactone R05395 cis-2,3-Dihydrodiol 1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + NAD+ <=> 2,3-Dihydroxy-1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + NADH + H+ R05396 cis-2,3-Dihydrodiol 1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + NADP+ <=> 2,3-Dihydroxy-1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane + NADPH + H+ R05397 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase; 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,6-Dichlorocatechol + NADH + H+ R05398 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + 2 H+ + 2 e- <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethane R05399 NADH:2-hydroxy-1,4-benzoquinone oxidoreductase; 2-Hydroxy-1,4-benzoquinone + NADH + H+ <=> Benzene-1,2,4-triol + NAD+ R05400 hydroxylaminobenzene:NADP+ oxidoreductase; Nitrosobenzene + NADPH + H+ <=> Hydroxylaminobenzene + NADP+ R05401 nitrosobenzene:NADP+ oxidoreductase; Nitrobenzene + NADPH + H+ <=> Nitrosobenzene + NADP+ + H2O R05402 glutathione disulfide:2,6-dichlorohydroquinone (chlorinating); Tetrachlorohydroquinone + 2 Glutathione <=> 2,3,6-Trichlorohydroquinone + Glutathione disulfide + Hydrochloric acid R05403 glutathione disulfide:2,6-dichlorohydroquinone (chlorinating); 2,3,6-Trichlorohydroquinone + 2 Glutathione <=> 2,6-Dichlorohydroquinone + Glutathione disulfide + Hydrochloric acid R05404 3-Vinylcatechol + Oxygen <=> 2-Hydroxy-6-oxoocta-2,4,7-trienoate R05405 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing); 2-Aminophenol + Oxygen <=> 2-Aminomuconate semialdehyde R05406 catechol:oxygen 2,3-oxidoreductase (ring-opening); 4-Chlorocatechol + Oxygen <=> 5-Chloro-2-hydroxymuconic semialdehyde R05407 3,5-Dichlorocatechol + Oxygen <=> 2,4-Dichloro-cis,cis-muconate R05408 2,6-Dichlorohydroquinone + Oxygen + H2O <=> 2-Chloromaleylacetate + Hydrochloric acid R05409 3,6-Dichlorocatechol + Oxygen <=> 2,5-Dichloro-cis,cis-muconate R05410 3,4-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid R05411 2,2',3-Trihydroxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate R05412 1,2-Dihydroxyfluorene + Oxygen <=> 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid R05413 2,2',3-Trihydroxydiphenylether + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate R05414 9H-carbazole,NADH:oxygen oxidoreductase (2,3-hydroxylating); Carbazole + Oxygen + NADH + H+ <=> 2'-Aminobiphenyl-2,3-diol + NAD+ R05415 2'-Aminobiphenyl-2,3-diol + Oxygen <=> 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate R05416 3-Ethylcatechol + Oxygen <=> 2-Hydroxy-6-oxo-octa-2,4-dienoate + H+ R05417 Styrene + Oxygen + NADH + H+ <=> Styrene-cis-2,3-dihydrodiol + NAD+ R05418 2,4,5-Trichlorophenoxyacetic acid + Oxygen + NADH + H+ <=> 2,4,5-Trichlorophenol + Glyoxylate + NAD+ + H2O R05419 2,4-Dichlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Glyoxylate + Succinate + CO2 R05420 4-sulfomuconolactone sulfohydrolase; 4-Sulfolactone + H2O <=> HSO3- + 2-Maleylacetate + H+ R05421 Parathion + H2O <=> Diethylthiophosphoric acid + 4-Nitrophenol R05422 fluorene,NADH:oxygen oxidoreductase; Fluorene + Oxygen + NADH + H+ <=> Fluoren-9-ol + NAD+ + H2O R05423 Fluorene + Oxygen + NADH + H+ <=> (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene + NAD+ R05424 Ethylbenzene <=> Styrene + 2 H+ R05425 Ethylbenzene + Oxygen + NADH + H+ <=> (S)-1-Phenylethanol + NAD+ + H2O R05426 (S)-1-Phenylethanol + Oxygen + NADH + H+ <=> Acetophenone + NAD+ + 2 H2O R05427 2 Acetophenone + Oxygen <=> 2 2-Hydroxyacetophenone R05428 o-Toluate + Oxygen + NADH + H+ <=> 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ R05429 1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating); 1,4-Dichlorobenzene + Oxygen + NADH + H+ <=> 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ R05430 2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 Dihydrocoumarin + 2 NAD+ R05431 2 Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NAD+ R05432 2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 Dihydrocoumarin + 2 NADP+ R05433 2 Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Hydroxy-1-indanone + 2 NADP+ R05434 Dibenzofuran + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxybiphenyl + NAD+ R05435 Fluoren-9-one + Oxygen + 2 NADH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NAD+ R05436 Fluoren-9-one + Oxygen + 2 NADPH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NADP+ R05437 2 2-Indanone + Oxygen + 2 NADH + 2 H+ <=> 2 3-Isochromanone + 2 NAD+ R05438 2 2-Indanone + Oxygen + 2 NADPH + 2 H+ <=> 2 3-Isochromanone + 2 NADP+ R05439 Dibenzo-p-dioxin + Oxygen + NADH + H+ <=> 2,2',3-Trihydroxydiphenylether + NAD+ R05440 Ethylbenzene + Oxygen + NADH + H+ <=> cis-1,2-Dihydro-3-ethylcatechol + NAD+ R05441 4-chlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating); 4-Chlorophenol + Oxygen + NADPH + H+ <=> 4-Chlorocatechol + NADP+ + H2O R05442 o-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating); o-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 2-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O R05443 m-xylene,ferredoxin:oxygen oxidoreductase (methyl-hydroxylating); m-Xylene + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> 3-Methylbenzyl alcohol + 2 Oxidized ferredoxin + H2O R05444 Ethylene + Oxygen + NADH + H+ <=> Ethylene oxide + NAD+ + H2O R05445 2,6-Dichlorohydroquinone + H2O <=> 6-Chlorobenzene-1,2,4-triol + Hydrochloric acid R05446 2,5-Dichlorohydroquinone + FADH2 + Oxygen <=> 5-Chloro-2-hydroxy-p-benzoquinone + FAD + H2O + Cl- R05447 2,4,5-Trichlorophenol + FADH2 + Oxygen <=> 2,5-Dichloro-p-benzoquinone + FAD + H2O + Cl- R05448 2,6-Dichlorophenol + Oxygen + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+ + H2O R05449 2,4,6-trichlorophenol,FADH2:oxygen oxidoreductase (dechlorinating); 2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2,6-Dichloro-p-benzoquinone + FAD + H2O + Cl- R05450 2-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> Homogentisate + NAD+ + H2O R05451 2,4-dichlorobenzoate:CoA ligase; CoA + ATP + 2,4-Dichlorobenzoate <=> Diphosphate + 2,4-Dichlorobenzoyl-CoA + AMP R05452 benzoylacetate:CoA ligase (AMP-forming); 3-Oxo-3-phenylpropanoate + CoA + ATP <=> Diphosphate + Benzoylacetyl-CoA + AMP R05453 acetophenone:carbon-dioxide ligase (ADP-forming); 2 ATP + Acetophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 Orthophosphate + 3-Oxo-3-phenylpropanoate R05454 2-Succinylbenzoate <=> Spirodilactone + H2O R05455 2-Succinylbenzoyl-CoA <=> Spirodilactone + CoA R05459 tetracycline:coenzyme-F420 oxidoreductase; Tetracycline + Coenzyme F420 <=> 5a,11a-Dehydrotetracycline + Reduced coenzyme F420 R05462 4-hydroxy-6-methylpretetramide,NADPH:oxygen oxidoreductase (12a-hydroxylating); 4-Hydroxy-6-methylpretetramide + NADPH + Oxygen + H+ <=> 4-Keto-anhydrotetracycline + NADP+ + H2O R05463 6-methylpretetramide,NADPH:oxygen oxidoreductase (4-hydroxylating); 6-Methylpretetramide + NADPH + Oxygen + H+ <=> 4-Hydroxy-6-methylpretetramide + NADP+ + H2O R05465 D-Glyceraldehyde 3-phosphate + L-Arginine <=> L-N2-(2-Carboxyethyl)arginine + Orthophosphate R05466 deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + Oxygen <=> Guanidinoproclavaminic acid + Succinate + CO2 R05467 L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming); L-N2-(2-Carboxyethyl)arginine + ATP <=> Deoxyguanidinoproclavaminic acid + AMP + Diphosphate R05468 proclavaminate,2-oxoglutarate:oxygen oxidoreductase (cyclyzing); Proclavaminic acid + Oxygen + 2-Oxoglutarate <=> Dihydroclavaminic acid + CO2 + Succinate + H2O R05469 dihydroclavaminate,2-oxoglutarate:oxygen oxidoreductase (desaturating); Dihydroclavaminic acid + Oxygen + 2-Oxoglutarate <=> Clavaminic acid + Succinate + CO2 + H2O R05470 Clavaminic acid <=> Clavulanate-9-aldehyde R05471 clavulanate:NADP+ oxidoreductase; Clavulanate-9-aldehyde + NADPH + H+ <=> Clavulanic acid + NADP+ R05472 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate <=> 4-Chlorobenzoate R05473 Bis(4'-chlorophenyl)methane <=> 4-Chlorophenylacetate R05474 2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chlorophenylacetate R05475 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene + NADH + H+ + Oxygen <=> cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ R05476 DDT <=> TDE + Cl- R05477 1-Chloro-2,2-bis(4'-chlorophenyl)ethane + H2O <=> 2,2-Bis(4'-chlorophenyl)ethanol + Hydrochloric acid R05478 2,2-Bis(4'-chlorophenyl)ethanol <=> unsym-Bis(4'-chlorophenyl)ethylene + H2O R05479 Bis(4'-chlorophenyl)acetate <=> 4,4'-Dichlorobenzophenone R05480 2-(4'-Chlorophenyl)-3,3-dichloropropenoate <=> 4-Chloroacetophenone R05481 Bis(4'-chlorophenyl)acetate <=> 2,2-Bis(4'-chlorophenyl)ethanol + H2O R05482 Hydroquinone + Nitrite + 7 H+ + 6 e- <=> 4-Hydroxyaniline + 3 H2O R05483 1,2,4-Trichlorobenzene + Hydrochloric acid <=> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene R05484 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <=> 2,5-Dichlorophenol + Hydrochloric acid R05485 Aminoparathion + H2O <=> Diethylthiophosphoric acid + 4-Hydroxyaniline R05486 Diethylthiophosphoric acid + H2O <=> Diethylphosphoric acid + Hydrogen sulfide R05487 phenylacetate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating); Phenylacetic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-Hydroxyphenylacetate + [Oxidized NADPH---hemoprotein reductase] + H2O R05488 styrene,FADH2:oxygen oxidoreductase; Styrene + FADH2 + Oxygen <=> (S)-2-Phenyloxirane + FAD + H2O R05492 DDT + Oxygen <=> cis-2,3-Dihydrodiol 1,1,1-trichloro-2,2-bis(4'-chlorophenyl)ethane R05493 4-Chlorophenoxyacetate + 2-Oxoglutarate + Oxygen <=> 4-Chlorophenol + Glyoxylate + Succinate + CO2 R05495 Ethylbenzene + H2O <=> 1-Phenylethanol + 2 H+ R05496 reduced ferredoxin:acetylene oxidoreductase (ATP-hydrolysing); Acetylene + Reduced ferredoxin + 2 H+ + ATP + H2O <=> Ethylene + Oxidized ferredoxin + ADP + Orthophosphate R05497 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene <=> 1-Chloro-2,2-bis(4'-chlorophenyl)ethylene + Cl- R05498 Vinyl chloride + 2 H+ <=> Ethylene + Hydrochloric acid R05499 Tetrachloroethene + 2 H+ <=> Trichloroethene + Hydrochloric acid R05500 Trichloroethene + 2 H+ <=> trans-1,2-Dichloroethene + Hydrochloric acid R05501 Trichloroethene + 2 H+ <=> cis-1,2-Dichloroethene + Hydrochloric acid R05502 trans-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid R05503 cis-1,2-Dichloroethene + 2 H+ <=> Vinyl chloride + Hydrochloric acid R05504 5-Chloro-2-hydroxymuconic semialdehyde + H+ <=> 2-Hydroxymuconate semialdehyde + Cl- R05505 2,4-Dichlorophenoxyacetate + H+ + 2 e- <=> 4-Chlorophenoxyacetate + Cl- R05506 Benzoylacetyl-CoA + CoA <=> Benzoyl-CoA + Acetyl-CoA R05507 6-aminohexanoate:2-oxogutarate aminotransferase; 6-Aminohexanoate + 2-Oxoglutarate <=> Adipate semialdehyde + L-Glutamate R05508 Lactoyl-CoA + Acetate <=> (S)-Lactate + Acetyl-CoA R05509 Acetyl-CoA + Acrylic acid <=> Acetate + Propenoyl-CoA R05510 protoanemonin lactonohydrolase; Protoanemonin + H2O <=> cis-Acetylacrylate R05511 cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-Chloromaleylacetate R05512 D-Glucose 1-phosphate + Nucleoside triphosphate + Amino group donor + Activated methyl group <=> NDP-N-methyl-L-glucosamine + Orthophosphate R05515 Streptomycin 6-phosphate + NADH + H+ <=> Dihydrostreptomycin 6-phosphate + NAD+ R05516 dTDP-L-rhamnose <=> dTDP-L-dihydrostreptose R05518 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose hydro-lyase (dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose-forming); dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + H2O R05519 Erythromycin + Oxygen <=> Erythromycin E + H2O R05520 S-adenosyl-L-methionine:erythromycin-C 3''-O-methyltransferase; S-Adenosyl-L-methionine + Erythromycin C <=> S-Adenosyl-L-homocysteine + Erythromycin R05521 erythromycin-B,NADPH:oxygen oxidoreductase (12-hydroxylating); Erythromycin B + NADPH + H+ + Oxygen <=> Erythromycin + NADP+ + H2O R05522 erythromycin-D,NADPH:oxygen oxidoreductase (12-hydroxylating); Erythromycin D + NADPH + H+ + Oxygen <=> Erythromycin C + NADP+ + H2O R05526 dTDP-4-oxo-2,6-dideoxy-D-glucose:NADP+ 3-oxidoreductase; dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-glucose + NADP+ R05530 dTDP-L-mycarose:erythronolide-B 3-O-alpha-mycarosyltransferase; Erythronolide B + dTDP-L-mycarose <=> 3-O-alpha-Mycarosylerythronolide B + dTDP R05531 dTDP-D-desosamine:3-O-mycarosylerythronolide-B 5-O-beta-D-desosaminyltransferase; dTDP-D-desosamine + 3-O-alpha-Mycarosylerythronolide B <=> Erythromycin D + dTDP R05532 S-adenosyl-L-methionine:erythromycin-D 3''-O-methyltransferase; S-Adenosyl-L-methionine + Erythromycin D <=> S-Adenosyl-L-homocysteine + Erythromycin B R05533 beta-1,2,3,4,5,6-Hexachlorocyclohexane <=> delta-3,4,5,6-Tetrachlorocyclohexene + 2 Cl- R05534 delta-3,4,5,6-Tetrachlorocyclohexene <=> 5,6-Dichloro-1,3-cyclohexadiene + 2 Cl- R05535 5,6-Dichloro-1,3-cyclohexadiene <=> Chlorobenzene + Cl- + H+ R05536 5,6-Dichloro-1,3-cyclohexadiene <=> Benzene + 2 Cl- R05537 3-(2-Hydroxyphenyl)propanoate + ATP + CoA + FAD + NAD+ <=> Salicylate + AMP + Diphosphate + FADH2 + Acetyl-CoA + NADH + H+ R05538 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid + H2O <=> 2-Formyl-1-indanone + Pyruvate R05539 CO2 <=> 3-Isochromanone R05540 2 Indanone + 2 CO2 <=> 2 2-Formyl-1-indanone + Oxygen R05541 Fluorene + Oxygen + 2 H+ <=> 3,4-Dihydroxyfluorene R05542 Fluorene + Oxygen + 2 H+ <=> 1,2-Dihydroxyfluorene R05543 3,4-Dihydroxy-3,4-dihydro-9-fluorenone <=> 4-Hydroxy-9-fluorenone + H2O R05544 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid + H2O <=> 1-Formyl-2-indanone + Pyruvate R05545 1-Formyl-2-indanone + H2O <=> 2-Indanone + CO2 + 2 H+ + 2 e- R05546 2-Amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 H2O <=> 1,4-Cyclohexanedione + Ammonia + CO2 + CoA R05547 N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine R05548 Paraoxon + H2O <=> Diethylphosphoric acid + 4-Nitrophenol R05549 D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose R05551 Acrylic acid + Ammonia <=> Acrylamide + H2O R05552 Chorismate + Ammonia <=> 4-Amino-4-deoxychorismate + H2O R05553 4-amino-4-deoxychorismate pyruvate-lyase; 4-Amino-4-deoxychorismate <=> 4-Aminobenzoate + Pyruvate R05554 ureidoglycine aminohydrolase; (S)-ureidoglycine aminohydrolase; (S)-Ureidoglycine + H2O <=> (S)-Ureidoglycolate + Ammonia R05555 farnesyl diphosphate:isopentenyl diphosphate farnesyl cistransferase; trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> trans,trans,cis-Geranylgeranyl diphosphate + Diphosphate R05556 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units); trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> ditrans,polycis-Polyprenyl diphosphate + n Diphosphate R05558 atrazine chlorohydrolase; Atrazine + H2O <=> Hydroxyatrazine + Hydrochloric acid R05559 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase; Hydroxyatrazine + H2O <=> N-Isopropylammelide + Ethylamine R05560 N-isopropylammelide isopropylaminohydrolase; N-Isopropylammelide + H2O <=> Cyanuric acid + Isopropylamine R05563 biuret amidohydrolase; Biuret + H2O <=> Urea-1-carboxylate + Ammonia R05564 2 Atrazine + Oxygen <=> 2 Deisopropylatrazine + 2 Acetone R05565 2 Atrazine + Oxygen <=> 2 Deethylatrazine + 2 Acetaldehyde R05566 UDP-N-acetyl-alpha-D-mannosamine:N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol 4-beta-N-acetylmannosaminyltransferase (configuration-inverting); UDP-N-acetyl-D-mannosamine + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol R05567 2 Deisopropylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetaldehyde R05568 2 Deethylatrazine + Oxygen <=> 2 Deisopropyldeethylatrazine + 2 Acetone R05569 Deisopropyldeethylatrazine + H2O <=> 2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + Ammonia R05570 protein-N(pi)-phosphohistidine:galactitol 1-phosphotransferase; Galactitol + Protein N(pi)-phospho-L-histidine <=> Galactitol 1-phosphate + Protein histidine R05571 galactitol-1-phosphate:NAD oxidoreductase; Galactitol 1-phosphate + NAD+ <=> D-Tagatose 6-phosphate + NADH + H+ R05572 Deisopropylatrazine + H2O <=> Deisopropylhydroxyatrazine + Hydrochloric acid R05573 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine ethylaminohydrolase; N-Ethylammelide + H2O <=> Cyanuric acid + Ethylamine R05574 deisopropylhydroxyatrazine aminohydrolase; Deisopropylhydroxyatrazine + H2O <=> N-Ethylammelide + Ammonia R05575 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA:NAD+ oxidoreductase; (2S)-[(R)-Hydroxy(phenyl)methyl]succinyl-CoA + NAD+ <=> (S)-2-Benzoylsuccinyl-CoA + NADH + H+ R05576 (S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase; 3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+ R05577 L-aspartate:tRNA(Asp) ligase (AMP-forming); tRNA(Asp) + L-Aspartate + ATP <=> L-Aspartyl-tRNA(Asp) + Diphosphate + AMP R05578 L-glutamate:tRNA(Glu) ligase (AMP-forming); tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP R05579 glutaryl-CoA:(acceptor) 2,3-oxidoreductase (non-decarboxylating); Glutaryl-CoA + Acceptor <=> Glutaconyl-1-CoA + Reduced acceptor R05580 CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein R05581 6-hydroxycyclohex-1-ene-1-carbonyl-CoA:NAD+ 6-oxidoreductase; 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ <=> 6-Oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+ R05582 2-Hydroxycyclohexane-1-carbonyl-CoA + NAD+ <=> 2-Oxocyclohexane-1-carbonyl-CoA + NADH + H+ R05583 2,6-Dihydroxycyclohexane-1-carbonyl-CoA + Acceptor <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + Reduced acceptor R05584 (R)-benzylsuccinyl-CoA:electron transfer flavoprotein oxidoreductase; Benzylsuccinyl-CoA + 2 Electron-transferring flavoprotein <=> E-Phenylitaconyl-CoA + 2 Reduced electron-transferring flavoprotein R05585 Anthraniloyl-CoA + 2 H+ <=> Benzoyl-CoA + Ammonia R05586 3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA R05587 (S)-2-Benzoylsuccinyl-CoA + CoA <=> Benzoyl-CoA + Succinyl-CoA R05588 Benzylsuccinate + Succinyl-CoA <=> Benzylsuccinyl-CoA + Succinate R05590 acylamide aminohydrolase; Benzamide + H2O <=> Benzoate + Ammonia R05591 nitrile aminohydrolase; Benzonitrile + 2 H2O <=> Benzoate + Ammonia R05592 2-Oxocyclohexane-1-carbonyl-CoA + H2O <=> Pimeloyl-CoA R05593 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA hydrolase (decyclizing); 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA R05594 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (decyclizing); 6-Oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-Hydroxypimeloyl-CoA R05595 Crotonoyl-CoA + H2O <=> 3-Hydroxybutanoyl-CoA R05596 benzamide hydro-lyase; Benzonitrile + H2O <=> Benzamide R05597 6-hydroxycyclohex-1-ene-1-carbonyl-CoA hydro-lyase (cyclohexa-1,5-diene-1-carbonyl-CoA-forming); Cyclohexa-1,5-diene-1-carbonyl-CoA + H2O <=> 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA R05598 benzylsuccinate fumarate-lyase; Toluene + Fumarate <=> Benzylsuccinate R05599 (R,S)-2-(alpha-hydroxybenzyl)succinyl-CoA hydro-lyase; E-Phenylitaconyl-CoA + H2O <=> (2S)-[(R)-Hydroxy(phenyl)methyl]succinyl-CoA R05600 Cyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxycyclohexane-1-carbonyl-CoA R05601 6-Carboxyhex-2-enoyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA R05602 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2,6-Dihydroxycyclohexane-1-carbonyl-CoA R05603 4-hydroxybenzoate carboxy-lyase (phenyl phosphate-forming); Phenolic phosphate + CO2 + H2O <=> 4-Hydroxybenzoate + Orthophosphate R05604 D-arabinitol:NAD 4-oxidoreductase; D-Arabitol + NAD+ <=> D-Xylulose + NADH + H+ R05605 2-dehydro-3-deoxy-6-phospho-D-gluconate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-6-phospho-D-gluconate <=> D-Glyceraldehyde 3-phosphate + Pyruvate R05606 D-mannonate hydro-lyase; D-Mannonate <=> 2-Dehydro-3-deoxy-D-gluconate + H2O R05607 D-sorbitol-6-phosphate:NAD 2-oxidoreductase; Sorbitol 6-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+ R05608 galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming); D-Galactarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O R05609 Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohexa-2,5-diene-1-carbonyl-CoA R05610 Cyclohexa-1,5-diene-1-carbonyl-CoA <=> Cyclohexa-1,4-diene-1-carbonyl-CoA R05611 all-trans-Octaprenyl diphosphate + Diphosphate <=> all-trans-Heptaprenyl diphosphate + Isopentenyl diphosphate R05612 all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Diphosphate R05613 all-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + Diphosphate R05615 all-trans-octaprenyl-diphosphate:4-hydroxybenzoate 3-octaprenyltransferase; all-trans-Octaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Octaprenyl-4-hydroxybenzoate + Diphosphate R05616 all-trans-hexaprenyl diphosphate:4-hydroxybenzoate hexaprenyltransferase; all-trans-Hexaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Hexaprenyl-4-hydroxybenzoate + Diphosphate R05618 chlorophyll chlorophyllidohydrolase; Chlorophyll a + H2O <=> Chlorophyllide + Phytol R05619 Cyclohexane-1-carbonyl-CoA + Acceptor <=> Cyclohex-1-ene-1-carbonyl-CoA + Reduced acceptor R05620 Cyclohexane-1-carboxylate + CoA + ATP <=> Cyclohexane-1-carbonyl-CoA + AMP + Diphosphate R05621 Benzoate + NADH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ R05622 Benzoate + NADPH + H+ + Oxygen <=> (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+ R05623 N,N,N-trimethylamine,NADPH:oxygen oxidoreductase (N-oxide-forming); Trimethylamine + NADPH + H+ + Oxygen <=> Trimethylamine N-oxide + NADP+ + H2O R05624 2,6-beta-D-fructan fructanohydrolase; H2O + Levan(m+n) <=> Levan(m) + Levan(n) R05625 ATP:phenol phosphotransferase (AMP-forming); Phenol + ATP + H2O <=> Phenolic phosphate + AMP + Orthophosphate R05626 ATP:undecaprenol phosphotransferase; ATP + di-trans,poly-cis-Undecaprenol <=> ADP + di-trans,poly-cis-Undecaprenyl phosphate R05627 undecaprenyl-diphosphate phosphohydrolase; di-trans,poly-cis-Undecaprenyl diphosphate + H2O <=> di-trans,poly-cis-Undecaprenyl phosphate + Orthophosphate R05629 UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase; UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + MurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphospho-undecaprenol R05630 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine:undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine R05631 UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4--D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine + alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + Globoside R05632 1-hydroxy-2-naphthoate,NADH:oxygen oxidoreductase (2-hydroxylating, decarboxylating); 1-Hydroxy-2-naphthoate + NADH + H+ + Oxygen <=> Naphthalene-1,2-diol + CO2 + NAD+ + H2O R05633 CTP: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2-C-Methyl-D-erythritol 4-phosphate + CTP <=> 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Diphosphate R05634 ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase; 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP <=> 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP R05635 formyl-L-methionyl peptide amidohydrolase; Formyl-L-methionyl peptide + H2O <=> Methionyl peptide + Formate R05636 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); Pyruvate + D-Glyceraldehyde 3-phosphate <=> 1-Deoxy-D-xylulose 5-phosphate + CO2 R05637 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing); 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + CMP R05639 4,4-dimethyl-5a-cholesta-8,24-dien-3b-ol:NADP+ D14-oxidoreductase; 14-Demethyllanosterol + NADP+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ R05640 lanosterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving); Lanosterol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R05641 ergosterol:NADP+ Delta24(24(1))-oxidoreductase; Ergosterol + NADP+ <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H+ R05642 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate <=> cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate R05643 2-formylbenzoate:NAD+ oxidoreductase; 2-Carboxybenzaldehyde + NAD+ + H2O <=> Phthalate + NADH + H+ R05644 ATP:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase; ATP + D-glycero-beta-D-manno-Heptose 1-phosphate <=> Diphosphate + ADP-D-glycero-beta-D-manno-heptose R05645 D-glycero-beta-D-manno-heptose-7-phosphate aldose-ketose-isomerase; Sedoheptulose 7-phosphate <=> D-glycero-beta-D-manno-Heptose 7-phosphate R05646 ATP:D-glycero-beta-D-manno-heptose 7-phosphate 1-phosphotransferase; ATP + D-glycero-beta-D-manno-Heptose 7-phosphate <=> ADP + D-glycero-beta-D-manno-Heptose 1,7-bisphosphate R05647 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase; D-glycero-beta-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-Heptose 1-phosphate + Orthophosphate R05648 cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O <=> 1-Hydroxy-2-naphthaldehyde + Pyruvate R05649 1-Hydroxy-2-naphthaldehyde + NAD+ + H2O <=> 1-Hydroxy-2-naphthoate + NADH + H+ R05650 Phenanthrene-3,4-diol + Oxygen <=> 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate R05651 acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming); Sulfoacetaldehyde + Orthophosphate <=> Acetyl phosphate + Sulfite R05652 taurine:pyruvate aminotransferase; Taurine + Pyruvate <=> Sulfoacetaldehyde + L-Alanine R05653 phenanthrene 9,10-monooxygenase; Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-9,10-oxide + H2O + NAD+ R05654 phenanthrene 1,2-monooxygenase; Phenanthrene + Oxygen + NADH + H+ <=> Phenanthrene-1,2-oxide + H2O + NAD+ R05655 Phenanthrene + Oxygen + NADH + H+ <=> 1-Phenanthrol + H2O + NAD+ R05656 Phenanthrene-1,2-oxide <=> 1-Phenanthrol R05657 1-Phenanthrol + CH3-R <=> 1-Methoxyphenanthrene + R R05658 Phenanthrene-9,10-oxide + H2O <=> trans-9(S),10(S)-Dihydrodiolphenanthrene R05659 2,4,6/3,5-Pentahydroxycyclohexanone <=> D-2,3-Diketo 4-deoxy-epi-inositol + H2O R05661 ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase; 2-Deoxy-5-keto-D-gluconic acid + ATP <=> 2-Deoxy-5-keto-D-gluconic acid 6-phosphate + ADP R05662 UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase; MurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphospho-undecaprenol + UDP-N-acetyl-alpha-D-glucosamine <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + UDP R05663 2-Methylbenzaldehyde + NADP+ + H2O <=> o-Toluate + NADPH + H+ R05664 3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+ R05665 m-Methylbenzoate + NADH + Oxygen + H+ <=> 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ R05666 toluene,NADH:oxygen oxidoreductase (4-hydroxylating); Toluene + NADH + H+ + Oxygen <=> 4-Cresol + NAD+ + H2O R05668 ATP + NAD+ <=> 3'-Keto-3'-deoxy-ATP + NADH + H+ R05669 3'-Keto-3'-deoxy-ATP <=> 3'-Keto-3'-deoxy-AMP + Diphosphate R05670 3'-Keto-3'-deoxy-AMP <=> 3'-Amino-3'-deoxy-AMP R05671 3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate R05672 N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA R05673 N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine R05674 N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine R05675 N-Acetyl-O-demethylpuromycin-5'-phosphate <=> N-Acetyl-O-demethylpuromycin R05676 N-Acetyl-O-demethylpuromycin + S-Adenosyl-L-methionine <=> N-Acetylpuromycin + S-Adenosyl-L-homocysteine R05677 N-Acetylpuromycin + H2O <=> Puromycin + Acetate R05678 sulcatol:NAD+ oxidoreductase; Sulcatol + NAD+ <=> Sulcatone + NADH + H+ R05679 sn-glycerol-1-phosphate:NAD 2-oxidoreductase; sn-Glycerol 1-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+ R05680 sn-glycerol-1-phosphate:NADP 2-oxidoreductase; sn-Glycerol 1-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+ R05681 NAD-dependent threonine 4-phosphate dehydrogenase; O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 2-Amino-3-oxo-4-phosphonooxybutyrate + NADH + H+ R05682 1,5-anhydro-D-glucitol:NADP oxidoreductase; 1,5-Anhydro-D-glucitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ R05683 L-idonate:NAD oxidoreductase; L-Idonate + NAD+ <=> 5-Dehydro-D-gluconate + NADH + H+ R05684 L-idonate:NADP oxidoreductase; L-Idonate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ R05685 3-methylbutanol:NAD(P) oxidoreductase; 3-Methylbutanol + NAD+ <=> 3-Methylbutanal + NADH + H+ R05686 3-methylbutanol:NADP oxidoreductase; 3-Methylbutanol + NADP+ <=> 3-Methylbutanal + NADPH + H+ R05687 dTDP-4-keto-6-deoxyglucose reductase; dTDP-D-fucose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+ R05688 1-deoxy-D-xylulose-5-phosphate isomeroreductase; 2-C-Methyl-D-erythritol 4-phosphate + NADP+ <=> 1-Deoxy-D-xylulose 5-phosphate + NADPH + H+ R05689 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase; (R)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+ R05690 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase; (S)-2-Hydroxypropyl-CoM + NAD+ <=> 2-Oxopropyl-CoM + NADH + H+ R05691 lophenol:NADP+ 3-oxidoreductase; Lophenol + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + NADPH + H+ R05692 GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing); GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ R05693 (R)-2-hydroxyacid:NAD+ oxidoreductase; (S)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+ R05694 (S)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+ R05695 nucleoside:oxygen 5'-oxidoreductase (H2O2-forming); Adenosine + 2 Oxygen + H2O <=> 9-Riburonosyladenine + 2 Hydrogen peroxide R05696 Adenosine + Oxygen <=> 5'-Dehydroadenosine + Hydrogen peroxide R05697 5'-Dehydroadenosine + Oxygen + H2O <=> 9-Riburonosyladenine + Hydrogen peroxide R05698 mannitol:oxygen oxidoreductase (cyclizing); Mannitol + Oxygen <=> D-Mannose + Hydrogen peroxide R05699 vanillin:NAD oxidoreductase; 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O <=> Vanillate + NADH + H+ R05700 coniferyl aldehyde:NAD oxidoreductase; Coniferyl aldehyde + H2O + NAD+ <=> Ferulate + NADH + H+ R05701 coniferyl aldehyde:NADP oxidoreductase; Coniferyl aldehyde + H2O + NADP+ <=> Ferulate + NADPH + H+ R05702 dihydrozeatin:NADP oxidoreductase; Dihydrozeatin + NADP+ <=> Zeatin + NADPH + H+ R05703 lanosterol D24-reductase; Lathosterol + NADP+ <=> 5alpha-Cholesta-7,24-dien-3beta-ol + NADPH + H+ R05704 glycine:acceptor oxidoreductase (hydrogen-cyanide-forming); Glycine + 2 Acceptor <=> Hydrogen cyanide + CO2 + 2 Reduced acceptor R05705 FMNH2:NAD+ oxidoreductase; Reduced FMN + NAD+ <=> FMN + NADH + H+ R05706 FMNH2:NADP+ oxidoreductase; Reduced FMN + NADP+ <=> FMN + NADPH + H+ R05707 reduced-riboflavin:NADP+ oxidoreductase; Reduced riboflavin + NADP+ <=> Riboflavin + NADPH + H+ R05708 N6-dimethylallyladenine:(acceptor) oxidoreductase; N6-(Delta2-Isopentenyl)-adenine + H2O + Acceptor <=> Adenine + 3-Methyl-2-butenal + Reduced acceptor R05711 N,N-dimethyl-1,4-phenylenediamine,aniline:NADP+ oxidoreductase; N,N-Dimethyl-1,4-phenylenediamine + Aniline + 2 NADP+ <=> para-(Dimethylamino)azobenzene + 2 NADPH + 2 H+ R05712 ammonia:ferricytochrome-c oxidoreductase; Ammonia + 2 H2O + 6 Ferricytochrome c <=> Nitrite + 6 Ferrocytochrome c + 6 H+ R05713 2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating); Coenzyme M + Acetoacetate + NADP+ <=> 2-Oxopropyl-CoM + CO2 + NADPH + H+ R05714 CoA,glutathione:NADP+ oxidoreductase (disulfide-forming); NADPH:CoA-glutathione oxidoreductase; CoA + Glutathione + NADP+ <=> CoA-glutathione + NADPH + H+ R05715 mycothiol:NAD+ oxidoreductase; 2 Mycothiol + NAD+ <=> Mycothione + NADH + H+ R05716 mycothiol:NADP+ oxidoreductase; 2 Mycothiol + NADP+ <=> Mycothione + NADPH + H+ R05717 AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming); AMP + Sulfite + Glutathione disulfide <=> Adenylyl sulfate + 2 Glutathione R05718 linoleate:oxygen 11S-oxidoreductase; Linoleate + Oxygen <=> (9Z,12Z)-(11S)-11-Hydroperoxyoctadeca-9,12-dienoic acid R05719 3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming); 3-Hydroxy-1H-quinolin-4-one + Oxygen <=> Formylanthranilate + CO R05720 3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming); 3-Hydroxy-2-methyl-1H-quinolin-4-one + Oxygen <=> N-Acetylanthranilate + CO R05721 chloride:oxygen oxidoreductase; Cl- + Oxygen <=> Chlorous acid R05722 phytanoyl-CoA,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating); Phytanoyl-CoA + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyphytanoyl-CoA + Succinate + CO2 R05723 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; Leucocyanidin + 2-Oxoglutarate + Oxygen <=> Taxifolin + Succinate + CO2 + H2O R05724 nitric oxide,NAD(P)H2:oxygen oxidoreductase; 2 Nitric oxide + 2 Oxygen + NADH + H+ <=> 2 Nitrate + NAD+ R05725 nitric oxide,NADPH2:oxygen oxidoreductase; 2 Nitric oxide + 2 Oxygen + NADPH + H+ <=> 2 Nitrate + NADP+ R05727 quinine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Quinine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Hydroxyquinine + [Oxidized NADPH---hemoprotein reductase] + H2O R05728 (E)-4-hydroxyphenylacetaldehyde oxime,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase; (E)-4-Hydroxyphenylacetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-4-Hydroxymandelonitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R05729 alkene,NADH:oxygen oxidoreductase; Propylene + NADH + H+ + Oxygen <=> (2R)-1,2-Epoxypropane + NAD+ + H2O R05730 alkene,NADH:oxygen oxidoreductase; Propylene + NADH + H+ + Oxygen <=> (S)-1,2-Epoxypropane + NAD+ + H2O R05731 obtusifoliol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving); Obtusifoliol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R05732 (S)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); (S)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxy-N-methyl-(S)-coclaurine + [Oxidized NADPH---hemoprotein reductase] + H2O R05733 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 4alpha-Hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Ferricytochrome b5 + 2 H2O R05734 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O R05735 acetone:carbon-dioxide ligase (AMP-forming); Acetone + HCO3- + 2 ATP + 3 H2O <=> Acetoacetate + 2 AMP + 4 Orthophosphate R05739 choline,reduced-ferredoxin:oxygen oxidoreductase; Choline + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Betaine aldehyde hydrate + H2O + 2 Oxidized ferredoxin R05740 linoleate,ferrocytochrome-b5:oxygen oxidoreductase (12,13-dehydrogenating); Linoleate + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Crepenynate + 2 Ferricytochrome b5 + 2 H2O R05741 7-O-methylluteone:O2 oxidoreductase; 7-O-Methylluteone + NADPH + H+ + Oxygen <=> Dihydrofurano derivative + NADP+ + H2O R05742 thiophene-2-carbonyl-CoA,hydrogen-donor:oxygen oxidoreductase; Thiophene-2-carbonyl-CoA + Reduced acceptor + Oxygen <=> 5-Hydroxythiophene-2-carbonyl-CoA + Acceptor + H2O R05743 rubredoxin:superoxide oxidoreductase; Reduced rubredoxin + Superoxide + 2 H+ <=> Oxidized rubredoxin + Hydrogen peroxide R05744 trans-ferulate:CoASH ligase (ATP-hydrolysing); Ferulate + CoA + ATP <=> Feruloyl-CoA + Products of ATP breakdown R05745 ethylbenzene:(acceptor) oxidoreductase; Ethylbenzene + H2O + Acceptor <=> (S)-1-Phenylethanol + Reduced acceptor R05746 phosphonate:NAD+ oxidoreductase; Phosphonic acid + NAD+ + H2O <=> Orthophosphate + NADH + H+ R05747 glutharedoxin:arsenate oxidoreductase; Arsenate ion + Glutaredoxin <=> Arsenite + Glutaredoxin disulfide R05748 gluthathione:methylarsonate oxidoreductase; Methylarsonate + 2 Glutathione <=> Methanearsonous acid + Glutathione disulfide + H2O R05749 deacetylipecoside dopamine-lyase; Dopamine + Secologanin <=> Deacetylipecoside + H2O R05750 deacetylisoipecoside dopamine-lyase; Dopamine + Secologanin <=> Deacetylisoipecoside + H2O R05751 arsenite:azurin oxidoreductase; Arsenite + H2O + 2 Oxidized azurin <=> Arsenate ion + 2 Reduced azurin + 2 H+ R05752 arsenate:(acceptor) oxidoreductase; Arsenite + Acceptor <=> Arsenate ion + Reduced acceptor R05753 acceptor:trichloroethene oxidoreductase (chlorinating); Trichloroethene + Cl- + Acceptor <=> Tetrachloroethene + Reduced acceptor R05754 S-adenosyl-L-methionine:trichlorophenol O-methyltransferase; S-Adenosyl-L-methionine + 2,4,6-Trichlorophenol <=> S-Adenosyl-L-homocysteine + 2,4.6-Trichloroanisole R05757 S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase; S-Adenosyl-L-methionine + 3'-Demethylstaurosporine <=> S-Adenosyl-L-homocysteine + Staurosporine R05758 threo-3-hydroxy-L-aspartate ammonia-lyase; threo-3-Hydroxy-L-aspartate <=> Oxaloacetate + Ammonia R05759 S-adenosyl-L-methionine:jasmonate O-methyltransferase; S-Adenosyl-L-methionine + (-)-Jasmonic acid <=> S-Adenosyl-L-homocysteine + Methyl jasmonate R05760 S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase; S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + (24R)-24-Methylcycloart-25-en-3-beta-ol R05761 (R)-2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming); (R)-2-Hydroxypropyl-CoM <=> (2R)-1,2-Epoxypropane + Coenzyme M R05762 (S)-2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming); (S)-2-Hydroxypropyl-CoM <=> (S)-1,2-Epoxypropane + Coenzyme M R05763 S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase; S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-3-(Methoxycarbonyl)pent-2-enedioate R05764 S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase; S-Adenosyl-L-methionine + trans-Aconitate <=> S-Adenosyl-L-homocysteine + (E)-2-(Methoxycarbonylmethyl)butenedioate R05765 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-pinene-forming]; Geranyl diphosphate <=> (-)-alpha-Pinene + Diphosphate R05766 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-beta-pinene-forming]; Geranyl diphosphate <=> (-)-beta-Pinene + Diphosphate R05767 trehalose 6-phosphate:phosphate b-D-glucosyltransferase; alpha,alpha'-Trehalose 6-phosphate + Orthophosphate <=> D-Glucose 6-phosphate + beta-D-Glucose 1-phosphate R05768 GDP-mannose:3-phosphoglycerate 3-a-D-mannosyltransferase; GDP-mannose + 3-Phospho-D-glycerate <=> GDP + 2-(alpha-D-Mannosyl)-3-phosphoglycerate R05769 UDP-glucose:hydroquinone-O-b-D-glucosyltransferase; UDP-glucose + Hydroquinone <=> UDP + Arbutin R05771 N-cyclohexylformamide hydro-lyase; N-Cyclohexylformamide <=> Cyclohexyl isocyanide + H2O R05772 feruloyl-CoA hydro-lyase/vanillin-lyase (acetyl-CoA-forming); Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA R05773 feruloyl-CoA hydro-lyase/vanillin-lyase (acetyl-CoA-forming); 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA R05774 sulfopyruvate carboxy-lyase; 3-Sulfopyruvate <=> Sulfoacetaldehyde + CO2 R05775 UDP-6-sulfo-6-deoxyglucose sulfohydrolase; UDP-glucose + Sulfite <=> UDP-6-sulfoquinovose + H2O R05776 S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase; S-Adenosyl-L-methionine + 24-Methylenelophenol <=> S-Adenosyl-L-homocysteine + 24-Ethylidenelophenol R05777 diphospho-myo-inositol-polyphosphate diphosphohydrolase; Diphospho-myo-inositol polyphosphate + H2O <=> myo-Inositol polyphosphate + Orthophosphate R05778 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating); 3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> 4-Hydroxymandelate + CO2 R05779 5-diphosphoinositol pentakisphosphate diphosphohydrolase; 5-PP-InsP5 + H2O <=> Phytic acid + Orthophosphate R05780 thiocyanate aminohydrolase; Thiocyanate + 2 H2O <=> Carbonyl sulfide + Ammonia + HO- R05781 cyclic-imide amidohydrolase (decyclicizing); Maleimide + H2O <=> Maleamate R05782 N-carbamoyl-L-amino acid amidohydrolase; N-Carbamoyl-L-amino acid + H2O <=> L-Amino acid + Ammonia + CO2 R05783 mandelamide hydrolase; (R)-Mandelamide + H2O <=> (R)-Mandelate + Ammonia R05784 limonene-1,2-epoxide hydrolase; Limonene-1,2-epoxide + H2O <=> Limonene-1,2-diol R05788 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase; 6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranoside + H2O <=> 6-O-(beta-D-Xylopyranosyl)-beta-D-glucopyranose + Alcohol R05789 (R)-2-phospho-3-sulfolactate phosphohydrolase; (2R)-O-Phospho-3-sulfolactate + H2O <=> (2R)-3-Sulfolactate + Orthophosphate R05790 alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase; 2-(alpha-D-Mannosyl)-3-phosphoglycerate + H2O <=> 2-O-(alpha-D-Mannosyl)-D-glycerate + Orthophosphate R05791 2-O-(alpha-D-glucopyranosyl)-sn-glycerol-3-phosphate phosphohydrolase; 2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate R05792 acyloxyacyl hydrolase; 3-(Acyloxy)acyl group of bacterial toxin + 2 H2O <=> 3-Hydroxyacyl group of bacterial toxin + 2 Fatty acid R05793 cutin hydrolase; Cutin + H2O <=> Cutin monomer R05794 CDP-diacylglycerol:choline O-phosphatidyltransferase; CDP-diacylglycerol + Choline <=> CMP + Phosphatidylcholine R05795 ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase; ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate R05796 poly[(R)-3-hydroxyoctanoate] hydrolase; Poly[(R)-3-hydroxyoctanoate]n + H2O <=> Poly[(R)-3-hydroxyoctanoate]n + Poly[(R)-3-hydroxyoctanoate]x R05797 poly[(R)-3-hydroxybutyrate] hydrolase; Poly[(R)-3-hydroxybutanoate]n-x + H2O <=> Poly[(R)-3-hydroxybutanoate]n-x + Poly[(R)-3-hydroxybutanoate]x R05798 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + [Heparan sulfate]-glucosamine <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-glucosamine 3-sulfate R05799 ATP:1D-myo-inositol-hexakisphosphate phosphotransferase; ATP + Phytic acid <=> ADP + 1-Diphosinositol pentakisphosphate R05800 ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase; ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate R05801 ATP:1D-myo-inositol-1,4,5,6-tetrakisphosphate 3-phosphotransferase; ATP + 1D-myo-Inositol 1,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate R05802 ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase; ATP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate R05803 ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase; ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate R05804 ADP:D-glucose 6-phosphotransferase; ADP + D-Glucose <=> AMP + D-Glucose 6-phosphate R05805 ADP:D-fructose-6-phosphate 1-phosphotransferase; ADP + D-Fructose 6-phosphate <=> AMP + D-Fructose 1,6-bisphosphate R05806 ATP:deoxynucleoside 5'-phosphotransferase; ATP + Deoxynucleoside <=> ADP + Deoxynucleoside 5'-phosphate R05807 sirohydrochlorin cobalt-lyase; Sirohydrochlorin + Cobalt ion <=> Cobalt-sirohydrochlorin + 2 H+ R05808 S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase; Cobalt-sirohydrochlorin + S-Adenosyl-L-methionine <=> Cobalt-factor III + S-Adenosyl-L-homocysteine R05809 Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine R05810 cobalt-precorrin-4 methyltransferase; Cobalt-precorrin 4 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 5A + S-Adenosyl-L-homocysteine R05811 Cobalt-precorrin 5 + S-Adenosyl-L-methionine + H2O <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine + Acetaldehyde R05812 cobalt-precorrin-6B:NAD+ oxidoreductase; Cobalt-precorrin 6 + NADH + H+ <=> Cobalt-dihydro-precorrin 6 + NAD+ R05813 Cobalt-dihydro-precorrin 6 + 2 S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + 2 S-Adenosyl-L-homocysteine + CO2 R05814 precorrin-8 11,12-methylmutase; Cobalt-precorrin 8 <=> Cobyrinate R05815 cobyrinate:L-glutamine amido-ligase (ADP-forming); Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate R05816 (1->2)-(1->3)-alpha-D-mannan mannohydrolase; (1->2)-(1->6)-alpha-D-mannan D-mannohydrolase; Mannan + H2O <=> D-Mannose + Mannan R05817 (3Z)-phycocyanobilin:ferredoxin oxidoreductase; Biliverdin + 4 Reduced ferredoxin <=> (3Z)-Phycocyanobilin + 4 Oxidized ferredoxin R05818 15,16-dihydrobiliverdin:ferredoxin oxidoreductase; Biliverdin + Reduced ferredoxin <=> 15,16-Dihydrobiliverdin + Oxidized ferredoxin R05819 (3Z)-phycoerythrobilin:ferredoxin oxidoreductase; 15,16-Dihydrobiliverdin + Reduced ferredoxin <=> (3Z)-Phycoerythrobilin + Oxidized ferredoxin R05820 protein-N(pi)-phosphohistidine:D-sorbitol 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Sorbitol <=> Protein histidine + Sorbitol 6-phosphate R05821 inosine:oxygen 5'-oxidoreductase; Inosine + Oxygen <=> 9-Riburonosylhypoxanthine + H2O R05822 5'-oxoinosine:oxygen 5'-oxidoreductase; 2 5'-Oxoinosine + Oxygen <=> 2 9-Riburonosylhypoxanthine R05823 2-dehydro-D-gluconate:NADP+ 2-oxidoreductase; 2-Keto-D-gluconic acid + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+ R05824 4,21-Dehydrocorynantheine aldehyde <=> 4,21-Dehydrogeissoschizine R05825 polyneuridine aldehyde hydrolase (decarboxylating); Polyneuridine aldehyde + H2O <=> 16-Epivellosimine + CO2 + Methanol R05826 16-Epivellosimine <=> Vellosimine R05827 10-deoxysarpagine:NADP+ oxidoreductase; 10-Deoxysarpagine + NADP+ <=> Vellosimine + NADPH + H+ R05828 10-deoxysarpagine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10-hydroxylating); 10-Deoxysarpagine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sarpagine + [Oxidized NADPH---hemoprotein reductase] + H2O R05829 (19E)-geissoschizine:[oxidized NADPH---hemoprotein reductase] oxidoreductase (polyneuridine aldehyde forming); (19E)-Geissoschizine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Polyneuridine aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R05830 2-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase; 2-Hydroxy-vitamin K + Oxidized dithiothreitol <=> Vitamin K1 epoxide + Dithiothreitol R05831 xylitol:NAD oxidoreductase; Xylitol + NAD+ <=> L-Xylulose + NADH + H+ R05832 7-deoxyloganate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating); 7-Deoxyloganate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Loganate + [Oxidized NADPH---hemoprotein reductase] + H2O R05833 loganate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ring-cleaving); Loganate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Secologanate + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R05834 S-adenosyl-L-methionine:secologanate 11-O-methyltransferase; S-Adenosyl-L-methionine + Secologanate <=> S-Adenosyl-L-homocysteine + Secologanin R05835 glycocholate amidohydrolase; Glycocholate + H2O <=> Cholic acid + Glycine R05836 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + 2 H+ <=> Deoxycholic acid R05837 4-(phosphonooxy)threonine:NAD oxidoreductase; O-Phospho-4-hydroxy-L-threonine + NAD+ <=> 3-Amino-2-oxopropyl phosphate + NADH + H+ + CO2 R05838 pyridoxine 5'-phosphate synthase; 3-Amino-2-oxopropyl phosphate + 1-Deoxy-D-xylulose 5-phosphate <=> Pyridoxine phosphate + Orthophosphate + 2 H2O R05839 pyridoxamine:2-oxoglutarate aminotransferase; Pyridoxamine + 2-Oxoglutarate <=> Pyridoxal + D-Glutamate R05840 Glycolaldehyde + 2-Oxobutanoate + Alanine <=> Pyridoxine R05841 phenylacetyl-CoA:glycine N-phenylacetyltransferase; Phenylacetyl-CoA + Glycine <=> Phenylacetylglycine + CoA R05842 ethylene oxide hydrolase; Ethylene oxide + H2O <=> Ethylene glycol R05843 Phenanthrene + NADH + H+ + Oxygen <=> (+)-cis-3,4-Dihydrophenanthrene-3,4-diol + NAD+ R05844 Strictosidine aglycone <=> Dialdehyde R05845 Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine aldehyde + H2O R05846 4,21-Dehydrogeissoschizine <=> Cathenamine R05847 Cathenamine + NADPH + H+ <=> Ajmalicine + NADP+ R05848 Cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+ R05849 Ajmalicine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serpentine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+ R05850 L-ribulose-5-phosphate 4-epimerase; L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate R05855 tabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (16-hydroxylating); Tabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxytabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O R05856 16-Methoxytabersonine + H2O <=> 16-Methoxy-2,3-dihydro-3-hydroxytabersonine R05857 desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4b-hydroxylating); Desacetoxyvindoline + 2-Oxoglutarate + Oxygen <=> Deacetylvindoline + Succinate + CO2 R05858 Vindoline + Catharanthine <=> 3',4'-Anhydrovinblastine R05859 3',4'-Anhydrovinblastine <=> Vinblastine R05860 Vinblastine <=> Vincristine R05861 D-alanine:oxygen oxidoreductase (deaminating); D-Alanine + H2O + Oxygen <=> Pyruvate + Ammonia + Hydrogen peroxide R05862 sarcosine:oxygen oxidoreductase (deaminating); Sarcosine + H2O + Oxygen <=> Glyoxylate + Methylamine + Hydrogen peroxide R05863 N-ethylglycine:oxygen oxidoreductase (deaminating); N-Ethylglycine + H2O + Oxygen <=> Glyoxylate + Ethylamine + Hydrogen peroxide R05864 4-hydroxy-2-oxohexanoate hydro-lyase; 2-Hydroxy-cis-hex-2,4-dienoate + H2O <=> 4-Hydroxy-2-oxohexanoic acid R05865 2-hydroxy-5-methyl-cis,cis-muconic-semialdehyde formylhydrolase; 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + H2O <=> Formate + 2-Hydroxy-cis-hex-2,4-dienoate R05866 Tabersonine + NADPH + H+ + Oxygen <=> Lochnericine + NADP+ + H2O R05867 Lochnericine <=> Horhammericine R05868 Tabersonine <=> Horhammericine R05869 Tabersonine <=> Minovincinine R05870 Minovincinine + Acetyl-CoA <=> Echitovenine + CoA R05871 19-Hydroxytabersonine <=> Horhammericine R05872 Tabersonine <=> 19-Hydroxytabersonine R05873 4,21-Dehydrogeissoschizine <=> 19-epi-Cathenamine R05874 19-epi-Cathenamine + NADPH + H+ <=> 19-epi-Ajmalicine + NADP+ R05875 [2Fe-2S]-ferredoxin:NAD+ oxidoreductase; 2 Reduced [2Fe-2S] ferredoxin + NAD+ + H+ <=> 2 Oxidized [2Fe-2S] ferredoxin + NADH R05876 acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing); Acetyl-CoA + 16-Epivellosimine <=> CoA + Vinorine R05877 vinorine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (21alpha-hydroxylating); Vinorine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Vomilenine + [Oxidized NADPH---hemoprotein reductase] + H2O R05878 1,2-dihydrovomilenine:NADP+ oxidoreductase; 1,2-Dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+ R05879 17-O-acetylnorajmaline:NADP+ oxidoreductase; 17-O-Acetylnorajmaline + NADP+ <=> 1,2-Dihydrovomilenine + NADPH + H+ R05880 17-O-acetylnorajmaline O-acetylhydrolase; 17-O-Acetylnorajmaline + H2O <=> Norajmaline + Acetate R05881 S-adenosyl-L-methionine:norajmaline N-methyltransferase; Norajmaline + S-Adenosyl-L-methionine <=> Ajmaline + S-Adenosyl-L-homocysteine R05882 UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase; UDP-glucose + Vomilenine <=> UDP + Raucaffricine R05884 isopentenyl-diphosphate:ferredoxin oxidoreductase; 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + 2 Reduced ferredoxin + 2 H+ <=> Isopentenyl diphosphate + 2 Oxidized ferredoxin + H2O R05885 S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase; 16-Hydroxytabersonine + S-Adenosyl-L-methionine <=> 16-Methoxytabersonine + S-Adenosyl-L-homocysteine + H+ R05886 Tabersonine <=> Lochnerinine R05887 Deacetylipecoside <=> Demethylalangiside R05888 Demethylalangiside <=> Alangiside R05889 Deacetylisoipecoside <=> Demethylisoalangiside R05890 Demethylisoalangiside <=> Isoalangiside R05894 Protoemetine <=> Tubulosine R05895 Protoemetine + Tryptamine <=> Deoxytubulosine R05896 Deoxytubulosine <=> Alangimarckine R05897 Protoemetine <=> Ankorine R05898 Loganate <=> 10-Deoxygeniposidic acid R05899 10-Deoxygeniposidic acid <=> Geniposidic acid R05900 Geniposidic acid <=> Asperuloside R05901 UDP-N-acetyl-D-glucosamine + G00025 <=> UDP + G00209 R05902 UDP-N-acetyl-D-glucosamine + Galactosylgloboside <=> UDP + G00102 R05903 UDP-D-galactose + G00102 <=> UDP + G00103 R05904 GDP-L-fucose + G00103 <=> GDP + G00104 R05905 CMP-N-acetylneuraminate + G00393 <=> CMP + G00251 R05906 CMP-N-acetylneuraminate + G00837 <=> CMP + G00251 R05907 UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen R05908 UDP-D-galactose + Tn antigen <=> UDP + Thomsen-Friedenreich antigen R05909 UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00028 R05910 UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00031 R05911 CMP-N-acetylneuraminate + Tn antigen <=> CMP + Sialyl-Tn antigen R05912 UDP-N-acetyl-D-glucosamine + Thomsen-Friedenreich antigen <=> UDP + G00025 R05913 CMP-N-acetylneuraminate + Thomsen-Friedenreich antigen <=> CMP + Sialyl T antigen R05914 CMP-N-acetylneuraminate + Sialyl T antigen <=> CMP + G00027 R05915 UDP-N-acetyl-D-glucosamine + G00028 <=> UDP + G00029 R05916 UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143 R05917 G00143 + H2O <=> G00144 + Acetate R05918 G00144 + Palmitoyl-CoA <=> G00145 + CoA R05919 Dolichyl phosphate D-mannose + G00145 <=> Dolichyl phosphate + G00146 R05922 Dolichyl phosphate D-mannose + G00148 <=> Dolichyl phosphate + G00149 R05923 Phosphatidylethanolamine + G00140 <=> 1,2-Diacyl-sn-glycerol + G00141 R05924 Phosphatidylethanolamine + G00141 <=> 1,2-Diacyl-sn-glycerol + G00151 R05925 UDP-D-xylose + [Protein]-L-serine <=> UDP + G00154 R05926 UDP-D-galactose + G00154 <=> UDP + G00155 R05927 UDP-D-galactose + G00155 <=> UDP + G00156 R05928 UDP-D-glucuronate + G00156 <=> UDP + G00157 R05929 UDP-N-acetyl-D-galactosamine + G00157 <=> UDP + G00158 R05930 UDP-N-acetyl-D-glucosamine + G00157 <=> UDP + G00162 R05931 UDP-D-glucuronate + G00158 <=> UDP + G00159 R05932 UDP-N-acetyl-D-galactosamine + G00159 <=> UDP + G00160 R05933 UDP-D-glucuronate + G00160 <=> UDP + G00180 R05934 UDP-N-acetyl-D-galactosamine + G00180 <=> UDP + G00161 R05935 UDP-D-glucuronate + G00162 <=> UDP + G00163 R05936 UDP-N-acetyl-D-glucosamine + G00163 <=> UDP + G00164 R05937 CMP-N-acetylneuraminate + Lactosylceramide <=> CMP + GM3 R05938 UDP-N-acetyl-D-galactosamine + Lactosylceramide <=> UDP + GA2 R05939 UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + GM2 R05940 CMP-N-acetylneuraminate + GM3 <=> CMP + GD3 R05941 UDP-D-galactose + GM2 <=> UDP + GM1 R05942 CMP-N-acetylneuraminate + GM1 <=> CMP + GD1a R05943 CMP-N-acetylneuraminate + GD1a <=> CMP + GT1a R05944 GDP-L-fucose + GM1 <=> GDP + Fucosyl-GM1 R05945 CMP-N-acetylneuraminate + GD1a <=> CMP + GT1aalpha R05946 UDP-N-acetyl-D-galactosamine + GD3 <=> UDP + GD2 R05947 CMP-N-acetylneuraminate + GD3 <=> CMP + GT3 R05948 UDP-D-galactose + GD2 <=> UDP + GD1b R05949 CMP-N-acetylneuraminate + GD1b <=> CMP + GT1b R05950 CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1b R05951 CMP-N-acetylneuraminate + GT1b <=> CMP + GQ1balpha R05952 UDP-N-acetyl-D-galactosamine + GT3 <=> UDP + GT2 R05953 UDP-D-galactose + GT2 <=> UDP + GT1c R05954 CMP-N-acetylneuraminate + GT1c <=> CMP + GQ1c R05955 CMP-N-acetylneuraminate + GQ1c <=> CMP + GP1c R05956 UDP-D-galactose + GA2 <=> UDP + Asialo-GM1 R05957 CMP-N-acetylneuraminate + Asialo-GM1 <=> CMP + GM1b R05958 CMP-N-acetylneuraminate + GM1b <=> CMP + GD1c R05959 CMP-N-acetylneuraminate + GM1b <=> CMP + GD1a R05960 UDP-D-galactose + Lactosylceramide <=> UDP + Globotriaosylceramide R05961 H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide R05962 UDP-N-acetyl-D-galactosamine + Globotriaosylceramide <=> UDP + Globoside R05963 H2O + Globoside <=> N-Acetyl-D-galactosamine + Globotriaosylceramide R05964 UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside R05965 UDP-N-acetyl-D-galactosamine + Globoside <=> UDP + Forssman antigen R05966 H2O + Forssman antigen <=> N-Acetyl-D-galactosamine + Globoside R05967 CMP-N-acetylneuraminate + Galactosylgloboside <=> CMP + Monosialylgalactosylgloboside R05968 GDP-L-fucose + Galactosylgloboside <=> GDP + Globo-H R05969 UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol R05970 UDP-N-acetyl-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Chitobiosyldiphosphodolichol R05971 UDP-N-acetyl-D-glucosamine + Lactosylceramide <=> UDP + Lc3Cer R05972 GDP-D-mannose + N,N'-Chitobiosyldiphosphodolichol <=> GDP + G00003 R05973 GDP-D-mannose + G00003 <=> GDP + G00004 R05974 UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer R05975 UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer R05976 Protein asparagine + G00008 <=> Dolichyl diphosphate + G00009 R05977 UDP-D-galactose + Lc3Cer <=> UDP + Paragloboside R05978 UDP-D-galactose + Paragloboside <=> UDP + IV3Gala-nLc4-Cer R05979 H2O + G00009 <=> beta-D-Glucose + G00171 R05980 Glc2Man9GlcNAc2-[protein] 3-alpha-glucohydrolase (configuration-inverting); H2O + G00171 <=> D-Glucose + G00010 R05981 GlcMan9GlcNAc2-[protein] 3-alpha-glucohydrolase (configuration-inverting); H2O + G00010 <=> D-Glucose + G00011 R05983 UDP-N-acetyl-D-glucosamine + G00012 <=> UDP + G00013 R05984 G00013 + 2 H2O <=> G00014 + 2 alpha-D-Mannose R05985 UDP-N-acetyl-D-glucosamine + G00014 <=> UDP + G00015 R05986 UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00019 R05987 UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00020 R05988 GDP-L-fucose + G00015 <=> GDP + Core fucose R05989 UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase; 2 UDP-D-galactose + Core fucose <=> 2 UDP + G00017 R05990 CMP-N-acetylneuraminate:beta-D-galactosyl 1,4-N-acetyl-beta-D-glucosamine alpha 2,6-N-acetylneuraminyltransferase; 2 CMP-N-acetylneuraminate + G00017 <=> 2 CMP + DS 3 R05991 UDP-N-acetyl-D-glucosamine + G00020 <=> UDP + G00021 R05992 UDP-N-acetyl-D-glucosamine + G00021 <=> UDP + G00022 R05994 Asialo-GM1 + H2O <=> GA2 + D-Galactose R05995 CMP-N-acetylneuraminate + GT1a <=> CMP + GQ1b R05996 GT1b + N-Acetylneuraminate <=> GQ1b + H2O R05998 GT1b + H2O <=> GD1b + N-Acetylneuraminate R05999 Lactosylceramide + N-Acetylneuraminate <=> GM3 + H2O R06000 CMP-N-acetylneuraminate + GD1a <=> CMP + GT1b R06001 GA2 + H2O <=> Lactosylceramide + N-Acetyl-D-galactosamine R06003 CMP-N-acetylneuraminate + Asialo-GM1 <=> CMP + GM1 R06004 GM2 + H2O <=> GM3 + N-Acetyl-D-galactosamine R06005 CMP-N-acetylneuraminate + GM1 <=> CMP + GD1b R06006 UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer R06007 CMP-N-acetylneuraminate + GA2 <=> CMP + GM2 R06009 CMP-N-acetylneuraminate + GM2 <=> CMP + GD2 R06010 GM1 + H2O <=> GM2 + D-Galactose R06011 UDP-N-acetyl-D-galactosamine + GM3 <=> UDP + G00176 R06012 GM2 + H2O <=> GA2 + N-Acetylneuraminate R06013 UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + G00174 R06014 UDP-N-acetyl-D-glucosamine + G00172 <=> UDP + G07376 R06015 GDP-L-fucose + G00015 <=> GDP + G00178 R06016 UDP-D-xylose + G00015 <=> UDP + G00179 R06018 1,3-beta-D-Glucan(n) + Orthophosphate <=> 1,3-beta-D-Glucan(n-1) + D-Glucose 1-phosphate R06020 1,3-beta-D-Glucan(n) + UDP-D-glucose <=> 1,3-beta-D-Glucan(n+1) + UDP R06021 UDP-D-galactose + G00077 <=> UDP + iso-nLc8Cer R06022 1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase; 1,4-beta-D-Glucan(n) + Orthophosphate <=> 1,4-beta-D-Glucan(n-1) + D-Glucose 1-phosphate R06023 UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; 1,4-beta-D-Glucan(n) + UDP-D-glucose <=> 1,4-beta-D-Glucan(n+1) + UDP R06024 GDP-L-fucose + Paragloboside <=> GDP + IV2Fuc-nLc4Cer R06025 GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer R06026 CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside R06027 GDP-L-fucose + IV3Gala-nLc4-Cer <=> GDP + Type II B antigen R06028 UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase; beta-1,4-Poly-N-acetyl-D-glucosamine(n) + UDP-N-acetyl-D-glucosamine <=> beta-1,4-Poly-N-acetyl-D-glucosamine(n+1) + UDP R06029 UDP-D-galactose + IV2Fuc-nLc4Cer <=> UDP + Type II B antigen R06030 GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; 1,4-beta-D-Glucan(n+1) + GDP <=> 1,4-beta-D-Glucan(n) + GDP-glucose R06031 GDP-L-fucose + Gal-TypeIIA glycolipid <=> GDP + Type IIIH glycolipid R06032 CMP-N-acetylneuraminate + Sialyl-3-paragloboside <=> CMP + 3',8'-LD1 R06033 UDP-D-galactose + nLc5Cer <=> UDP + nLc6Cer R06034 sucrose:phosphate alpha-D-glucosyltransferase; Sucrose + Orthophosphate <=> D-Fructose + D-Glucose 1-phosphate R06035 GDP-L-fucose + nLc6Cer <=> GDP + VI2Fuc-nLc6 R06036 UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase; UDP-D-glucose + D-Fructose <=> Sucrose + UDP R06037 CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer R06038 GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer R06039 GDP-L-fucose + nLc8Cer <=> GDP + G00084 R06040 maltose:phosphate 1-beta-D-glucosyltransferase; Maltose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R06041 GDP-L-fucose + G00073 <=> GDP + G00074 R06042 1-alpha-D-galactosyl-myo-inositol:raffinose galactosyltransferase; Galactinol + Raffinose <=> Stachyose + myo-Inositol R06043 UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; UDP-D-glucose + D-Glucose 6-phosphate <=> UDP + Trehalose 6-phosphate R06044 trehalose 6-phosphate:phosphate beta-D-glucosyltransferase; Trehalose 6-phosphate + Orthophosphate <=> D-Glucose 6-phosphate + beta-D-Glucose 1-phosphate R06045 UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase; 1,3-alpha-D-Glucan(n) + UDP-D-glucose <=> 1,3-alpha-D-Glucan(n+1) + UDP R06046 beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyl-1,6-alpha-D-mannosyloligosaccharide R06047 UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol R06048 UDP-glucose + Indoxyl <=> UDP + Indican R06049 ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase; 1,4-alpha-D-Glucan(n) + ADP-glucose <=> 1,4-alpha-D-Glucan(n+1) + ADP R06050 1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase; 1,4-alpha-D-Glucan(n) + Orthophosphate <=> 1,4-alpha-D-Glucan(n-1) + D-Glucose 1-phosphate R06051 UDP-glucose:glycogen 4-alpha-D-glucosyltransferase; 1,4-alpha-D-Glucan(n) + UDP-D-glucose <=> 1,4-alpha-D-Glucan(n+1) + UDP R06052 sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase; 1,4-alpha-D-Glucan(n) + Sucrose <=> 1,4-alpha-D-Glucan(n+1) + D-Fructose R06053 a,a-trehalose:phosphate beta-D-glucosyltransferase; Trehalose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R06054 3-Deoxyoctulosonyl-lipopolysaccharide + H2O <=> 3-Deoxy-D-manno-octulosonate + Lipopolysaccharide R06055 UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase; UDP-D-galactose + N-Acetyl-D-glucosamine <=> N-Acetyllactosamine + UDP R06056 cellobiose:phosphate alpha-D-glucosyltransferase; Cellobiose + Orthophosphate <=> D-Glucose 1-phosphate + D-Glucose R06057 beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase; Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine R06058 3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase; Laminaribiose + Orthophosphate <=> D-Glucose + D-Glucose 1-phosphate R06059 sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase; G10497(n) + Sucrose <=> G10497(n+1) + D-Glucose R06061 alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase; 2 D-Glucose 1-phosphate <=> Maltose + 2 Orthophosphate R06062 UDP-D-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol R06063 5-Hydroxyisourate + H+ + H2O <=> (R)(-)-Allantoin + CO2 R06064 5-Hydroxyisourate + H+ + H2O <=> (S)-Allantoin + CO2 R06066 sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase; 1,6-alpha-D-Glucan(n) + Sucrose <=> 1,6-alpha-D-Glucan(n+1) + D-Fructose R06067 UDP-galactose:D-glucose 4-beta-D-galactotransferase; UDP-D-galactose + D-Glucose <=> Lactose + UDP R06068 n UDP-N-acetyl-D-glucosamine + n UDP-D-glucuronate <=> Hyaluronic acid + 2n UDP R06069 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase; 1,4-alpha-D-Glucan + n D-Glucose <=> n Maltose R06070 Raffinose + H2O <=> D-Galactose + Sucrose R06071 Galactinol + Sucrose <=> myo-Inositol + Raffinose R06072 UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase; Pectic acid(n) + UDP-D-galacturonate <=> Pectic acid(n+1) + UDP R06073 UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase; UDP-D-glucose + D-Fructose 6-phosphate <=> UDP + Sucrose 6'-phosphate R06074 beta-D-Mannosylphosphodecaprenol + 1,6-alpha-D-Mannosyloligosaccharide(n) <=> Decaprenol phosphate + 1,6-alpha-D-Mannosyloligosaccharide(n+1) R06075 GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer R06076 GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081 R06077 1,4-beta-D-Glucan(n+1) + H2O <=> 1,4-beta-D-Glucan(n) + beta-D-Glucose R06078 1,3-beta-D-Glucan(n+1) + H2O <=> 1,3-beta-D-Glucan(n) + alpha-D-Glucose R06079 D-Glucose + G10499(n+1) <=> Sucrose + G10499(n) R06080 Isomaltose + H2O <=> alpha-D-Glucose + D-Glucose R06081 beta-1,4-Poly-N-acetyl-D-glucosamine(n+1) + H2O <=> N-Acetyl-D-glucosamine + beta-1,4-Poly-N-acetyl-D-glucosamine(n) R06082 beta-1,4-Poly-N-acetyl-D-glucosamine(n+2) + H2O <=> Chitobiose + beta-1,4-Poly-N-acetyl-D-glucosamine(n) R06083 Xylan(n) + UDP-D-xylose <=> Xylan(n+1) + UDP R06084 Maltose + H2O <=> 2 alpha-D-Glucose R06085 GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide R06086 GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079 R06087 Sucrose + H2O <=> D-Fructose + D-Glucose R06088 Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose R06089 GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide R06090 GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079 R06091 Melibiose + H2O <=> D-Galactose + D-Glucose R06092 Cellobiose + H2O <=> 2 beta-D-Glucose R06093 Galactinol + H2O <=> myo-Inositol + D-Galactose R06094 Galabiosylceramide + H2O <=> Galactosylceramide + D-Galactose R06095 GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer R06096 Manninotriose + H2O <=> D-Galactose + Melibiose R06097 UDP-D-galactose + nLc7Cer <=> UDP + nLc8Cer R06098 Lactose + H2O <=> alpha-D-Glucose + D-Galactose R06099 Lactosylceramide + H2O <=> Glucosylceramide + D-Galactose R06100 Raffinose + H2O <=> Melibiose + D-Fructose R06101 Stachyose + H2O <=> Manninotriose + D-Fructose R06102 Sucrose 6'-phosphate + H2O <=> beta-D-Fructose + alpha-D-Glucose 6-phosphate R06103 Trehalose + H2O <=> 2 D-Glucose R06104 Cellobiose + H2O <=> 2 D-Glucose R06105 Cellotriose + H2O <=> Cellobiose + D-Glucose R06106 Cellotetraose + H2O <=> Cellotriose + D-Glucose R06107 Cellopentaose + H2O <=> Cellotetraose + D-Glucose R06108 Celloheptaose + H2O <=> Cellohexaose + D-Glucose R06109 Cellohexaose + H2O <=> Cellopentaose + D-Glucose R06110 Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate R06112 G10518 + H2O <=> D-Glucose + D-Glucose 6-phosphate R06113 H2O + Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate R06114 Lactose + H2O <=> D-Glucose + beta-D-Galactose R06115 H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate R06116 Lc4 + H2O <=> Lacto-N-biose + Lactose R06117 (+)-trans-carveol: NAD+ oxidoreductase; (+)-trans-Carveol + NAD+ <=> (+)-(S)-Carvone + NADH + H+ R06118 G10523 + H2O <=> L-Fucose + Methyl beta-D-galactoside R06119 (R)-limonene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating); (R)-Limonene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-trans-Carveol + [Oxidized NADPH---hemoprotein reductase] + H2O R06120 geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming]; Geranyl diphosphate <=> (R)-Limonene + Diphosphate R06121 CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase; Lactosylceramide + CMP-N-acetylneuraminate <=> GM3 + CMP R06122 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase; Galabiosylceramide + 3'-Phosphoadenylyl sulfate <=> Digalactosylceramide sulfate + Adenosine 3',5'-bisphosphate R06124 alpha-Amino acid + H2O + Oxygen <=> 2-Oxo acid + Ammonia + Hydrogen peroxide R06125 GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; GDP-glucose + D-Glucose 6-phosphate <=> Trehalose 6-phosphate + GDP R06126 L-serine:NADP+ 3-oxidoreductase; L-Serine + NADP+ <=> 2-Aminomalonate semialdehyde + NADPH + H+ R06127 GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase; G00005 + GDP-D-mannose <=> G10526 + GDP R06128 GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase; G10526 + GDP-D-mannose <=> G00006 + GDP R06129 UDP-N-acetyl-D-mannosamine + N-Acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> N-Acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP R06130 UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase; Sucrose + UDP-D-galactose <=> Planteose + UDP R06131 alpha-Amino acid <=> 2-Oxo acid + Ammonia R06132 alpha-Amino acid <=> 2,3-Ene acid + Ammonia R06134 Amide + H2O <=> Carboxylate + Ammonia R06135 sucrose:sucrose 1F-beta-D-fructosyltransferase; 2 Sucrose <=> 1-Kestose + D-Glucose R06138 Amidine + H2O <=> Amide + Ammonia R06139 raffinose:raffinose alpha-D-galactosyltransferase; 2 Raffinose <=> G01504 + Sucrose R06140 Thomsen-Friedenreich antigen + H2O <=> G10607 + [Protein]-L-serine R06141 Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine R06142 Epimelibiose + H2O <=> D-Mannose + D-Galactose R06143 G10530 + H2O <=> N,6-O-Disulfo-D-glucosamine + D-Glucuronate R06144 3-Ketolactose + H2O <=> 3-Keto-beta-D-galactose + beta-D-Glucose R06145 N-Acetyllactosamine + UDP-D-galactose <=> Linear B type 2 trisaccharide + UDP R06147 Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O R06149 1,6-alpha-D-Mannosyloligosaccharide(n+1) + H2O <=> D-Mannose + G10542(n) R06150 G10540 + H2O <=> D-Mannose + G10542 R06151 G10541 + H2O <=> D-Mannose + G10542 R06152 Stachyose + H2O <=> Raffinose + D-Galactose R06153 CMP-N-acetylneuraminate + Lc4Cer <=> CMP + 3'-isoLM1 R06154 methylamine:oxygen oxidoreductase (deaminating) (copper-containing); Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide R06155 GDP-L-fucose + Lc4Cer <=> GDP + Fuc-Lc4Cer R06156 GDP-L-fucose + Lc4Cer <=> GDP + IV2Fuc-Lc4Cer R06157 G10544 + H2O <=> Starch + N-Acylsphingosine R06158 Starch + H2O <=> 1,4-alpha-D-Glucan + alpha-D-Glucose R06160 Cyclomaltodextrin + H2O <=> 1,4-alpha-D-Glucan R06161 Bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> Inulobiose R06162 GDP-L-fucose + Type IA glycolipid <=> GDP + ALeb glycolipid R06163 GDP-L-fucose + IV2Fuc-Lc4Cer <=> GDP + IV2Fuc,III4Fuc-Lc4Cer R06164 GDP-L-fucose + Type IB glycolipid <=> GDP + BLeb glycolipid R06165 GDP-L-fucose + 3'-isoLM1 <=> GDP + Fuc-3'-isoLM1 R06166 3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase; 3beta-Hydroxy-5beta-pregnane-20-one + NADP+ <=> 5beta-Pregnane-3,20-dione + NADPH + H+ R06167 UDP-N-acetyl-D-galactosamine + IV2Fuc-Lc4Cer <=> UDP + Type IA glycolipid R06168 UDP-D-galactose + IV2Fuc-Lc4Cer <=> UDP + Type IB glycolipid R06169 UDP-D-galactose + Lc4Cer <=> UDP + G00038 R06170 galactoside alpha-1,2-L-fucosyltransferase; GDP-L-fucose + G00038 <=> GDP + Type IB glycolipid R06171 L-allo-threonine acetaldehyde-lyase (glycine-forming); L-Allothreonine <=> Glycine + Acetaldehyde R06172 G10551 + UDP-N-acetyl-D-glucosamine <=> G10550 + UDP R06173 G10552 + UDP-N-acetyl-D-glucosamine <=> G10553 + UDP R06174 G10556 + UDP-N-acetyl-D-glucosamine <=> G10555 + UDP R06175 Chitosan(n+m) + H2O <=> Chitosan(n) + Chitosan(m) R06176 ATP + Cellobiose <=> ADP + G10518 R06177 G10555 + G10557(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10557(n+1) R06178 [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol polysaccharidetransferase; Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol <=> di-trans,poly-cis-Undecaprenyl diphosphate + [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-g-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol R06179 G10553 + G10554(n) <=> di-trans,poly-cis-Undecaprenyl diphosphate + G10554(n+1) R06180 (R,R)-Tartaric acid + NAD+ <=> 2-Hydroxy-3-oxosuccinate + NADH + H+ R06181 UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase; G10558 + UDP-D-glucose <=> G10559 + UDP R06182 UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) alpha-N-acetylglucosaminyltransferase; G10558 + UDP-N-acetyl-D-glucosamine <=> G10560 + UDP R06183 1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase; G10497(m) + G10497(n) <=> G10497(m-1) + G10497(n+1) R06184 1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase; 1,6-alpha-D-Glucan(m) + 1,4-alpha-D-Glucan(n) <=> 1,6-alpha-D-Glucan(m+1) + 1,4-alpha-D-Glucan(n-1) R06185 Starch + Orthophosphate <=> 1,4-alpha-D-Glucan + D-Glucose 1-phosphate R06186 1,4-alpha-D-Glucan <=> Starch R06187 UDP-N-acetyl-D-galactosamine + IV2Fuc-nLc4Cer <=> UDP + Type II A antigen R06188 CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase; N-Acetyllactosamine + CMP-N-acetylneuraminate <=> 6'-Sialyllactosamine + CMP R06189 UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + G00077 R06190 UDP-D-galactose + VI2Fuc-nLc6 <=> UDP + G00083 R06191 UDP-N-acetyl-D-galactosamine + G00074 <=> UDP + Type IIIAb R06192 UDP-D-galactose + G00072 <=> UDP + G00073 R06193 UDP-N-acetyl-D-galactosamine + VI2Fuc-nLc6 <=> UDP + G00072 R06194 Lumirhodopsin <=> Metarhodopsin R06195 ent-Kaurene <=> Aconitine R06196 ent-Kaurene <=> Veatchine R06197 UDP-N-acetyl-D-galactosamine + Type IIIH glycolipid <=> UDP + Type IIIA glycolipid R06198 UDP-D-galactose + Type II A antigen <=> UDP + Gal-TypeIIA glycolipid R06199 Starch(n+1) + H2O <=> alpha-D-Glucose + Starch(n) R06200 1,4-beta-D-Glucan(n+2) + H2O <=> 1,4-beta-D-Glucan(n) + Cellobiose R06201 Pectic acid(n+1) + H2O <=> D-Galacturonate + Pectic acid(n) R06202 G10534(n+1) + H2O <=> D-Galactose + G10534(n) R06203 D-Xylose + Xylan(n) <=> Xylan(n+1) + H2O R06204 1,3-beta-D-Glucan(n+1) + H2O <=> D-Glucose + 1,3-beta-D-Glucan(n) R06206 H2O + G10499(n+m) <=> G10499(n) + G10499(m) R06207 G10532(n+1) + H2O <=> D-Mannose + G10532(n) R06208 G10535(n+1) + H2O <=> D-Fructose + G10535(n) R06209 Starch(n+m) + H2O <=> Starch(n) + Starch(m) R06210 UDP-D-galactose + G10534(n) <=> G10534(n+1) + UDP R06211 Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate R06213 GDP-D-mannose + G10532(n) <=> GDP + G10532(n+1) R06214 UDP-D-galactose + myo-Inositol <=> UDP + Galactinol R06215 CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-6-paragloboside R06216 CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI6NeuAc-nLc6Cer R06217 Sucrose <=> Palatinose R06218 Maltose <=> Trehalose R06219 lactose:acceptor 3-oxidoreductase; Lactose + Acceptor <=> 3-Ketolactose + Reduced acceptor R06221 GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer R06222 GDP-L-fucose + G00084 <=> GDP + G00085 R06223 squalene synthase; 2 trans,trans-Farnesyl diphosphate + NADPH + H+ <=> Squalene + 2 Diphosphate + NADP+ R06224 GDP-L-fucose + G00085 <=> GDP + G00086 R06225 D-Glucosamine + Chitosan(n) <=> Chitosan(n+1) + H2O R06226 UDP-D-glucose + alpha-D-Glucose 6-phosphate <=> UDP + Trehalose 6-phosphate R06227 GDP-L-fucose + G00081 <=> GDP + Trifucosyl Lewis y R06228 Trehalose 6-phosphate + H2O <=> Trehalose + Orthophosphate R06229 Trehalose + Protein N(pi)-phospho-L-histidine <=> Trehalose 6-phosphate + Protein histidine R06230 GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer R06232 CMP-N-acetylneuraminate + V3Fuc-nLc6Cer <=> CMP + G00091 R06233 Sucrose + FAD <=> 3-Ketosucrose + FADH2 R06234 Galactosylceramide + UDP-D-galactose <=> Galabiosylceramide + UDP R06236 Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate R06237 Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate R06238 GDP-D-mannose:D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-6-mannosyltransferase; GDP-D-mannose + G00004 <=> GDP + G00005 R06239 Pectic acid(n+2) + H2O <=> G02614 + Pectic acid(n) R06240 Pectic acid(n+2) <=> G10113 + Pectic acid(n) R06241 beta-1,4-Poly-N-acetyl-D-glucosamine + n H2O <=> Chitosan + n Acetate R06242 Hyaluronic acid <=> n Hyaluronan-derived disaccharide R06243 1,4-alpha-D-Glucan(n+1) <=> G10589(n) R06244 Cellobiose + Oxygen <=> G10590 + Hydrogen peroxide R06245 Cellobiose <=> G01630 R06246 Cellobiose + Acceptor <=> G10590 + Reduced acceptor R06247 Cellobiose + Quinone <=> G10590 + Hydroquinone R06249 G10113 <=> 2 5-Dehydro-4-deoxy-D-glucuronate R06250 Pectin + n H2O <=> n Methanol + Pectic acid R06251 Acetyl-CoA + Maltose <=> CoA + Acetyl-maltose R06253 GM1 + N-Acetylneuraminate <=> GD1a + H2O R06254 2 I-Urobilinogen + Oxygen <=> 2 Urobilin + 2 H2O R06255 2 L-Urobilinogen + Oxygen <=> 2 L-Urobilin + 2 H2O R06256 D-Urobilinogen + 2 H+ <=> I-Urobilinogen R06257 I-Urobilinogen + 4 H+ <=> L-Urobilinogen R06258 Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595 R06259 Dolichyl phosphate D-mannose + G10595 <=> Dolichyl phosphate + G10596 R06260 Dolichyl phosphate D-mannose + G10596 <=> Dolichyl phosphate + G10597 R06261 Dolichyl phosphate D-mannose + G10597 <=> Dolichyl phosphate + G00007 R06262 dolichyl beta-D-glucosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase; Dolichyl D-glucosyl phosphate + G00007 <=> Dolichyl phosphate + G10598 R06263 dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase; Dolichyl D-glucosyl phosphate + G10598 <=> Dolichyl phosphate + G10599 R06264 dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-glucosyltransferase; Dolichyl D-glucosyl phosphate + G10599 <=> Dolichyl phosphate + G00008 R06265 magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating); Magnesium protoporphyrin monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O R06266 magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating); 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O R06267 magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating); 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + Oxygen <=> Divinylprotochlorophyllide + NADP+ + 2 H2O R06268 magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating); Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O <=> 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine R06269 magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating); 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine R06270 magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating); 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine <=> Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine R06271 Divinylprotochlorophyllide + 2 H+ <=> Protochlorophyllide R06272 chlorophyllide-a:NADP+ oxidoreductase; Divinyl chlorophyllide a + NADPH + H+ <=> Chlorophyllide + NADP+ R06273 CMP-N-acetylneuraminate + G04854 <=> CMP + G04461 R06274 CMP-N-acetylneuraminate + G04461 <=> CMP + G04135 R06275 UDP-D-glucose + N-Acylsphingosine <=> UDP + Glucosylceramide R06276 Glucosylceramide + UDP-D-galactose <=> Lactosylceramide + UDP R06277 UDP-D-galactose + N-Acylsphingosine <=> UDP + Galactosylceramide R06278 n UDP-D-galacturonate <=> n UDP + Pectin R06279 3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide R06280 Sulfatide + H2O <=> Galactosylceramide + Sulfate R06282 ATP-dependent ferredoxin:protochlorophyllide-a 7,8-oxidoreductase; Chlorophyllide + Oxidized ferredoxin + 2 ADP + 2 Orthophosphate <=> Protochlorophyllide + Reduced ferredoxin + 2 ATP + 2 H2O R06283 H2O + 3'-LM1-NeuGc <=> N-Acylsphingosine + nLc4 R06284 chlorophyllide-a:phytyl-diphosphate phytyltransferase; Chlorophyllide + Phytyl diphosphate <=> Chlorophyll a + Diphosphate R06285 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP R06286 chlorophyllide-a:NADP+ 7,8-oxidoreductase; Divinyl chlorophyllide a + NADP+ <=> Divinylprotochlorophyllide + NADPH + H+ R06287 Divinyl chlorophyllide a <=> Divinylchlorophyll a R06288 Divinylchlorophyll a <=> Chlorophyll a R06289 mycothiol:NAD(P)+ oxidoreductase; mycothione reductase; 2 Mycothiol + NAD+ <=> Mycothione + NADH + H+ R06290 mycothiol:NAD(P)+ oxidoreductase; 2 Mycothiol + NADP+ <=> Mycothione + NADPH + H+ R06291 ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); ent-Kaurene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R06292 ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Kaur-16-en-18-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R06293 ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Kaur-16-en-18-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R06294 ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Kaur-16-en-18-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R06295 ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R06296 ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6beta,7beta-Dihydroxykaurenoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R06297 ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Gibberellin A12 aldehyde + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 + [Oxidized NADPH---hemoprotein reductase] + H2O R06298 (+)-copalyl-diphosphate lyase (decyclizing); Geranylgeranyl diphosphate <=> Copalyl diphosphate R06299 (+)-copalyl-diphosphate diphosphate-lyase (pimaradiene-forming); Copalyl diphosphate <=> Pimaradiene + Diphosphate R06301 (+)-copalyl-diphosphate diphosphate-lyase [cyclizing, abieta-7,13-diene-forming]; Copalyl diphosphate <=> (-)-Abietadiene + Diphosphate R06302 (+)-copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]; Copalyl diphosphate <=> Levopimaradiene + Diphosphate R06303 (+)-copaly-diphosphate diphosphate-lyase (cyclizing, neoabietadiene-forming); Copalyl diphosphate <=> Neoabietadiene + Diphosphate R06304 (+)-copalyl-diphosphate diphosphate-lyase (palustradiene-forming); Copalyl diphosphate <=> Palustradiene + Diphosphate R06305 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene forming); Geranylgeranyl diphosphate <=> Taxa-4(5),11(12)-diene + Diphosphate R06306 taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating); Taxa-4(5),11(12)-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R06307 acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase; Taxa-4(20),11(12)-dien-5alpha-ol + Acetyl-CoA <=> Taxa-4(20),11(12)-dien-5alpha-yl acetate + CoA R06308 taxa-4(20),11-dien-5alpha-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (13alpha-hydroxylating); Taxa-4(20),11(12)-dien-5alpha-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha,13alpha-diol + [Oxidized NADPH---hemoprotein reductase] + H2O R06309 taxa-4(20),11-dien-5alpha-yl acetate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (10beta-hydroxylating); Taxa-4(20),11(12)-dien-5alpha-yl acetate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R06310 benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase; 10-Deacetyl-2-debenzoylbaccatin III + Benzoyl-CoA <=> 10-Deacetylbaccatin III + CoA R06311 acetyl-CoA:taxan-10beta-ol O-transferase; 10-Deacetylbaccatin III + Acetyl-CoA <=> Baccatin III + CoA R06312 9alpha-copalyl-diphosphate lyase (decyclizing); Geranylgeranyl diphosphate <=> 9alpha-Copalyl diphosphate R06313 9alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16beta-ol-forming); 9alpha-Copalyl diphosphate + H2O <=> Aphidicolan-16beta-ol + Diphosphate R06314 9alpha-Copalyl diphosphate <=> Aphidicol-16-ene R06315 9alpha-Copalyl diphosphate <=> Aphidicol-15-ene R06316 Aphidicolan-16beta-ol <=> Aphidicolin R06317 Aphidicol-16-ene <=> Aphidicolin R06318 Taxa-4(20),11(12)-dien-5alpha,13alpha-diol <=> 10-Deacetyl-2-debenzoylbaccatin III R06319 10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate <=> 10-Deacetyl-2-debenzoylbaccatin III R06320 Baccatin III <=> Paclitaxel R06321 Geranylgeranyl diphosphate <=> Cembrene R06322 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A12 + 2-Oxoglutarate + Oxygen <=> Gibberellin A15 open lactone + Succinate + CO2 R06323 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A15 open lactone + 2-Oxoglutarate + Oxygen <=> Gibberellin A24 + Succinate + CO2 + H2O R06324 Gibberellin A14 <=> Gibberellin A37 open lactone R06325 Gibberellin A37 open lactone <=> Gibberellin A36 R06326 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A24 <=> Gibberellin A9 + CO2 R06327 Gibberellin A36 <=> Gibberellin A4 + CO2 R06328 Gibberellin A12 aldehyde <=> Gibberellin A53 aldehyde R06329 Gibberellin A12 <=> Gibberellin A53 R06330 Gibberellin A15 open lactone <=> Gibberellin A44 diacid R06331 Gibberellin A24 <=> Gibberellin A19 R06332 Gibberellin A9 <=> Gibberellin A20 R06333 Gibberellin A12 <=> Gibberellin A14 R06334 Gibberellin A15 open lactone <=> Gibberellin A37 open lactone R06335 Gibberellin A24 + 2-Oxoglutarate + Oxygen <=> Gibberellin A36 + Succinate + CO2 R06336 (gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating); Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A4 + Succinate + CO2 R06337 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A9 + 2-Oxoglutarate + Oxygen <=> Gibberellin A51 + Succinate + CO2 R06338 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A4 + 2-Oxoglutarate + Oxygen <=> Gibberellin A34 + Succinate + CO2 R06339 Gibberellin A14 aldehyde <=> Gibberellin A14 R06340 Gibberellin A53 aldehyde <=> Gibberellin A53 R06341 Gibberellin A12 aldehyde <=> Gibberellin A14 aldehyde R06342 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A34 <=> Gibberellin A34-catabolite R06343 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A51 <=> Gibberellin A51-catabolite R06344 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A29 <=> Gibberellin A29-catabolite R06345 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating); Gibberellin A8 <=> Gibberellin A8-catabolite R06346 Gibberellin A20 <=> Gibberellin A5 R06347 Gibberellin A5 <=> Gibberellin A3 R06348 Gibberellin A5 <=> Gibberellin A6 R06349 Gibberellin A9 <=> 2,3-Dehydro-gibberellin A9 R06350 2,3-Dehydro-gibberellin A9 <=> Gibberellin A7 R06351 abieta-7,13-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating); (-)-Abietadiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietinol + [Oxidized NADPH---hemoprotein reductase] + H2O R06352 Levopimaradiene <=> Levopimarinol R06353 Neoabietadiene <=> Neoabietinol R06354 abietinol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating); Abietinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietal + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R06355 Levopimarinol <=> Levopimarinal R06356 Neoabietinol <=> Neoabietal R06357 abietadienal:NAD+ oxidoreductase; Abietal + H2O + NAD+ <=> Abietate + NADH + 2 H+ R06358 Levopimarinal <=> Levopimaric acid R06359 Neoabietal <=> Neoabietic acid R06361 acyl-CoA:isopenicillin N N-acyltransferase; Isopenicillin N + Acyl-CoA + H2O <=> Penicillin + CoA + L-2-Aminoadipate R06363 penicillin hydrolase; Penicillin + H2O <=> Penicilloic acid R06364 CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase; CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine R06365 O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate + NDP-N-methyl-L-glucosamine <=> Dihydrostreptomycin 6-phosphate + NDP R06366 aldehyde:NAD+ oxidoreductase; Perillyl aldehyde + H2O + NAD+ <=> Perillic acid + NADH + H+ R06367 perillic acid:CoA ligase (ADP-forming); Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + ADP + Orthophosphate R06368 perillic acid:CoA ligase (AMP-forming); Perillic acid + CoA + ATP <=> Perillyl-CoA + H2O + AMP + Diphosphate R06369 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA hydro-lyase; Perillyl-CoA + H2O <=> 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA R06370 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA + Acceptor <=> 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + Reduced acceptor R06371 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA + H2O <=> 3-Isopropenylpimelyl-CoA R06372 carvone reductase; (+)-(S)-Carvone + Reduced acceptor <=> (1R,4S)-Iso-dihydrocarvone + Acceptor R06373 carvone reductase; (-)-Carvone + Reduced acceptor <=> (1R,4R)-Dihydrocarvone + Acceptor R06374 (4R,6R)-cis-Carveol <=> (-)-Carvone R06375 (4S,6S)-cis-Carveol <=> (+)-(S)-Carvone R06376 menth-8-en-2-ol:NAD+ oxidoreductase; (1R,2R,4R)-Dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+ R06377 menth-8-en-2-ol:NAD+ oxidoreductase; (1R,2R,4S)-Iso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+ R06378 menth-8-en-2-ol:NAD+ oxidoreductase; (1R,2S,4R)-Neo-dihydrocarveol + NAD+ <=> (1R,4R)-Dihydrocarvone + NADH + H+ R06379 menth-8-en-2-ol:NAD+ oxidoreductase; (1R,2S,4S)-Neoiso-dihydrocarveol + NAD+ <=> (1R,4S)-Iso-dihydrocarvone + NADH + H+ R06380 (1R,4R)-Dihydrocarvone <=> (1S,4R)-Iso-dihydrocarvone R06381 (1R,4S)-Iso-dihydrocarvone <=> (1S,4S)-Dihydrocarvone R06382 menth-8-en-2-ol:NAD+ oxidoreductase; (1S,2S,4R)-Iso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+ R06383 menth-8-en-2-ol:NAD+ oxidoreductase; (1S,2S,4S)-Dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+ R06384 menth-8-en-2-ol:NAD+ oxidoreductase; (1S,2R,4R)-Neoiso-dihydrocarveol + NAD+ <=> (1S,4R)-Iso-dihydrocarvone + NADH + H+ R06385 menth-8-en-2-ol:NAD+ oxidoreductase; (1S,2R,4S)-Neo-dihydrocarveol + NAD+ <=> (1S,4S)-Dihydrocarvone + NADH + H+ R06386 monocyclic monoterpene ketone monooxygenase; (1R,4R)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O R06387 NADPH:oxygen oxidoreductase; (1R,4S)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O R06388 NADPH:oxygen oxidoreductase; (1S,4R)-Iso-dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O R06389 NADPH:oxygen oxidoreductase; (1S,4S)-Dihydrocarvone + NADPH + Oxygen + H+ <=> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O R06390 monoterpene epsilon-lactone hydrolase; (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3R)-6-Hydroxy-3-isopropenyl-heptanoate R06391 isopropenylmethyloxepan-2-one lactonohydrolase; (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate R06392 4-isopropenyl-7-methyloxepan-2-one lactonohydrolase; (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone + H2O <=> (3S)-6-Hydroxy-3-isopropenyl-heptanoate R06393 monoterpene epsilon-lactone hydrolase; (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O <=> (5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate R06394 (3R)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3R)-3-Isopropenyl-6-oxoheptanoate R06395 (3S)-6-Hydroxy-3-isopropenyl-heptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoate R06396 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming); (3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + ADP + Orthophosphate R06397 (3S)-3-Isopropenyl-6-oxoheptanoate <=> (3S)-3-Isopropenyl-6-oxoheptanoyl-CoA R06398 limonene 1,2-monooxygenase; (R)-Limonene + NADH + Oxygen + H+ <=> Limonene-1,2-epoxide + NAD+ + H2O R06399 (1S,2S,4R)-menth-8-ene-1,2-diol:NAD+ 2-oxidoreductase; Limonene-1,2-diol + NAD+ <=> (1S,4R)-1-Hydroxy-2-oxolimonene + NADH + H+ R06400 (1S,4R)-1-hydroxymenth-8-en-2-one,NADPH:oxygen oxidoreductase; (1S,4R)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O R06401 alpha-pinene dehydrogenase; alpha-Pinene + Reduced acceptor + Oxygen <=> Myrtenol + H2O + Acceptor R06402 myrtenol dehydrogenase; Myrtenol + Oxygen + Acceptor <=> Myrtenal + 2 H2O + Reduced acceptor R06403 myrtenal dehydrogenase; Myrtenal + H2O + Acceptor <=> Myrtenic acid + Reduced acceptor R06404 alpha-pinene monooxygenase; alpha-Pinene + Oxygen + 2 H+ + 2 e- <=> Pinocarveol + H2O R06405 pinocarveol dehydrogenase; Pinocarveol <=> Pinocarvone + H+ R06406 alpha-pinene monooxygenase; alpha-Pinene + NADH + H+ + Oxygen <=> alpha-Pinene-oxide + NAD+ + H2O R06407 cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase; (Z)-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+ R06408 trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase; trans-2-Methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + NADH + H+ R06409 cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase; cis-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate R06410 trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase; trans-2-Methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoA <=> trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + Diphosphate R06411 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA hydro-lyase; cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA R06412 trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase; trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA + H2O <=> 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA R06413 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase; 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ <=> 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH + H+ R06414 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase; 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoA <=> 3-Isopropylbut-3-enoyl-CoA + Propanoyl-CoA R06415 3-isopropylbut-3-enoyl-CoA thioesterase; 3-Isopropylbut-3-enoyl-CoA + H2O <=> 3-Isopropyl-3-butenoic acid + CoA R06417 (+)-cis-isopulegone:NADP+ oxidoreductase; (-)-Isopiperitenone + NADPH + H+ <=> (+)-cis-Isopulegone + NADP+ R06418 (+)-cis-isopulegone isomerase; (+)-cis-Isopulegone <=> Pulegone R06419 (-)-menthone:NADP+ oxidoreductase; Pulegone + NADPH + H+ <=> (-)-Menthone + NADP+ R06420 (+)-pulegone reductase; Pulegone + NADPH + H+ <=> (+)-Isomenthone + NADP+ R06421 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-terpineol-forming]; Geranyl diphosphate + H2O <=> (-)-alpha-Terpineol + Diphosphate R06422 (-)-alpha-Terpineol <=> 1,8-Cineole R06423 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose:2-oxoglutarate aminotransferase; 3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate <=> dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate R06424 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose isomerase; dTDP-4-oxo-6-deoxy-D-glucose <=> 3,6-Dideoxy-3-oxo-dTDP-D-glucose R06426 dTDP-3-amino-3,4,6-trideoxy-D-glucose:2-oxoglutarate aminotransferase; dTDP-3-oxo-4,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2-Oxoglutarate R06427 S-adenosyl-L-methionine:dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase; dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-desosamine + 2 S-Adenosyl-L-homocysteine R06428 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose hydro-lyase (dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose-forming); dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O R06433 dTDP-4-oxo-2,6-dideoxy-D-allose 5-epimerase; dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose R06434 dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ <=> dTDP-L-olivose + NADP+ R06436 dTDP-L-mycarose:NADP+ 4-oxidoreductase; dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ <=> dTDP-L-mycarose + NADP+ R06437 dTDP-4-dehydro-6-deoxy-alpha-D-glucose 3-epimerase; dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-oxo-6-deoxy-D-allose R06438 dTDP-6-deoxy-alpha-D-allose:NAD+ oxidoreductase; dTDP-6-deoxy-D-allose + NAD+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADH + H+ R06439 S-adenosyl-L-methionine:dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase; dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ R06443 dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> Maltol + dTDP R06445 dTDP-4-dehydro-beta-L-rhamnose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose R06446 dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-D-olivose R06447 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units); trans,trans-Farnesyl diphosphate + 8 Isopentenyl diphosphate <=> di-trans,poly-cis-Undecaprenyl diphosphate + 8 Diphosphate R06448 5 Methylmalonyl-CoA + 2 Malonyl-CoA + (2S)-Ethylmalonyl-CoA + 7 NADPH + 7 H+ <=> 8 CoA + Tylactone + 8 CO2 + 3 H2O + 7 NADP+ R06449 5-O-beta-D-Mycaminosyltylactone + 2 NADPH + 2 Oxygen + 2 H+ <=> 20-Oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O R06450 dTDP-alpha-D-mycaminose:tylactone 5-O-beta-D-mycaminosyltransferase; Tylactone + dTDP-D-mycaminose <=> 5-O-beta-D-Mycaminosyltylactone + dTDP R06451 dTDP-6-deoxy-alpha-D-allose:5-O-beta-D-mycaminosyltylonolide 23-O-6-deoxy-beta-D-allosyltransferase; 5-O-beta-D-Mycaminosyltylonolide + dTDP-6-deoxy-D-allose <=> Demethyllactenocin + dTDP R06452 dTDP-L-mycarose:demethyllactenocin 4'-O-alpha-mycarosyltransferase; Demethyllactenocin + dTDP-L-mycarose <=> Demethylmacrocin + dTDP R06453 Malonyl-CoA + 6 Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-Deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+ R06454 8,8a-Deoxyoleandolide + 2 NADPH + 2 H+ + 2 Oxygen <=> Oleandolide + 2 NADP+ + 3 H2O R06455 Oleandolide + dTDP-L-olivose <=> L-Olivosyl-oleandolide + dTDP R06456 S-adenosyl-L-methionine:L-olivosyl-oleandolide B 3-O-methyltransferase; L-Olivosyl-oleandolide + S-Adenosyl-L-methionine <=> L-Oleandrosyl-oleandolide + S-Adenosyl-L-homocysteine R06457 L-Oleandrosyl-oleandolide + dTDP-D-desosamine <=> Oleandomycin + dTDP R06458 (2S)-methylmalonyl-CoA:malonyl-CoA malonyltransferase (10-deoxymethynolide forming); 5 (S)-Methylmalonyl-CoA + Malonyl-CoA + 5 NADPH + 5 H+ <=> 10-Deoxymethynolide + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O R06459 (2S)-methylmalonyl-CoA:malonyl-CoA malonyltransferase (narbonolide forming); 6 (S)-Methylmalonyl-CoA + Malonyl-CoA + 5 NADPH + 5 H+ <=> Narbonolide + 7 CoA + 7 CO2 + 5 NADP+ + 2 H2O R06460 dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:10-deoxymethynolide 3-dimethylamino-4,6-dideoxy-alpha-D-glucosyltransferase; 10-Deoxymethynolide + dTDP-D-desosamine <=> 10-Deoxymethymycin + dTDP R06461 dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:narbonolide 3-dimethylamino-4,6-dideoxy-alpha-D-glucosyltransferase; Narbonolide + dTDP-D-desosamine <=> Narbomycin + dTDP R06462 10-deoxymethymycin,reduced ferredoxin:oxygen oxidoreductase (neomethymycin-forming); 10-Deoxymethymycin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Neomethymycin + 2 Oxidized ferredoxin + H2O R06463 10-deoxymethymycin,reduced ferredoxin:oxygen oxidoreductase (methymycin-forming); 10-Deoxymethymycin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Methymycin + 2 Oxidized ferredoxin + H2O R06464 narbomycin,reduced ferredoxin:oxygen oxidoreductase (pikromycin-forming); Narbomycin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pikromycin + 2 Oxidized ferredoxin + H2O R06465 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O R06466 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, lupeol-forming); (S)-2,3-Epoxysqualene <=> Lupeol R06467 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1a'' aglycone + NADP+ + H2O R06468 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O R06469 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, beta-amyrin-forming); (S)-2,3-Epoxysqualene <=> beta-Amyrin R06470 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''1b'' aglycone + NADP+ + H2O R06471 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-amyrin-forming); (S)-2,3-Epoxysqualene <=> alpha-Amyrin R06472 5-Oxoavermectin ''2a'' aglycone + NADPH + H+ <=> Avermectin B2a aglycone + NADP+ R06473 5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+ R06474 5-Oxoavermectin ''2b'' aglycone + NADPH + H+ <=> Avermectin B2b aglycone + NADP+ R06475 5-Oxoavermectin ''1b'' aglycone + NADPH + H+ <=> Avermectin B1b aglycone + NADP+ R06476 Avermectin B2a aglycone + S-Adenosyl-L-methionine <=> Avermectin A2a aglycone + S-Adenosyl-L-homocysteine R06477 Avermectin B1a aglycone + S-Adenosyl-L-methionine <=> Avermectin A1a aglycone + S-Adenosyl-L-homocysteine R06478 Avermectin B2b aglycone + S-Adenosyl-L-methionine <=> Avermectin A2b aglycone + S-Adenosyl-L-homocysteine R06479 Avermectin B1b aglycone + S-Adenosyl-L-methionine <=> Avermectin A1b aglycone + S-Adenosyl-L-homocysteine R06480 2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ R06481 2-Methylbutanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1a'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ R06482 2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ R06483 2-Methylpropanoyl-CoA + 5 Methylmalonyl-CoA + 7 Malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''1b'' aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ R06484 Avermectin B2a aglycone + dTDP-L-oleandrose <=> Avermectin B2a monosaccharide + dTDP R06485 Avermectin B2a monosaccharide + dTDP-L-oleandrose <=> Avermectin B2a + dTDP R06486 Avermectin A2a aglycone + dTDP-L-oleandrose <=> Avermectin A2a monosaccharide + dTDP R06487 Avermectin A2a monosaccharide + dTDP-L-oleandrose <=> Avermectin A2a + dTDP R06488 Avermectin B1a aglycone + dTDP-L-oleandrose <=> Avermectin B1a monosaccharide + dTDP R06489 Avermectin B1a monosaccharide + dTDP-L-oleandrose <=> Avermectin B1a + dTDP R06490 Avermectin A1a aglycone + dTDP-L-oleandrose <=> Avermectin A1a monosaccharide + dTDP R06491 Avermectin A1a monosaccharide + dTDP-L-oleandrose <=> Avermectin A1a + dTDP R06492 Avermectin B2b aglycone + dTDP-L-oleandrose <=> Avermectin B2b monosaccharide + dTDP R06493 Avermectin B2b monosaccharide + dTDP-L-oleandrose <=> Avermectin B2b + dTDP R06494 Avermectin A2b aglycone + dTDP-L-oleandrose <=> Avermectin A2b monosaccharide + dTDP R06495 Avermectin A2b monosaccharide + dTDP-L-oleandrose <=> Avermectin A2b + dTDP R06496 Avermectin B1b aglycone + dTDP-L-oleandrose <=> Avermectin B1b monosaccharide + dTDP R06497 Avermectin B1b monosaccharide + dTDP-L-oleandrose <=> Avermectin B1b + dTDP R06498 Avermectin A1b aglycone + dTDP-L-oleandrose <=> Avermectin A1b monosaccharide + dTDP R06499 Avermectin A1b monosaccharide + dTDP-L-oleandrose <=> Avermectin A1b + dTDP R06500 Soyasapogenol B <=> Soyasaponin I R06501 beta-Amyrin + Oxygen <=> Soyasapogenol B R06502 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate Delta8,11-Delta7,9-isomerase (trans-double-bond-forming); (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid <=> (5Z,7E,9E,14Z,17Z)-Icosapentaenoate R06503 Megalomicin A <=> Megalomicin B R06504 Megalomicin A <=> Megalomicin C1 R06505 Megalomicin A <=> Megalomicin C2 R06506 Erythromycin C + dTDP-L-megosamine <=> Megalomicin A + dTDP R06510 Acetyl-CoA + 2 Malonyl-CoA <=> Triacetate lactone + 3 CoA + 2 CO2 R06513 dTDPglucose 4,6-hydro-lyase; dTDP-glucose <=> dTDP-4-oxo-6-deoxy-D-glucose + H2O R06514 dTDP-4-dehydro-6-deoxy-alpha-D-glucose 3,5-epimerase; dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase; dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose R06515 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming); (3R)-3-Isopropenyl-6-oxoheptanoate + CoA + ATP <=> (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA + H2O + AMP + Diphosphate R06516 sphingosine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming); Sphingosine 1-phosphate <=> Ethanolamine phosphate + Hexadecenal R06517 acyl-CoA:sphingosine N-acyltransferase; Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide R06518 N-acylsphingosine amidohydrolase; Dihydroceramide + H2O <=> Fatty acid + Sphinganine R06519 dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (4,5-dehydrogenating); Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O R06520 3-sn-phosphatidate phosphohydrolase; Sphinganine 1-phosphate + H2O <=> Sphinganine + Orthophosphate R06521 3-sn-phosphatidate phosphohydrolase; Sphingosine 1-phosphate + H2O <=> Sphingosine + Orthophosphate R06522 3-sn-phosphatidate phosphohydrolase; Ceramide 1-phosphate + H2O <=> N-Acylsphingosine + Orthophosphate R06523 trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming); trans,trans-Farnesyl diphosphate <=> Vetispiradiene + Diphosphate R06525 sphinganine,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating); Sphinganine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytosphingosine + 2 Ferricytochrome b5 + H2O R06526 dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating); Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytoceramide + 2 Ferricytochrome b5 + H2O R06527 acyl-CoA: phytosphingosine N-acyltransferase; C26-CoA + Phytosphingosine <=> CoA + Phytoceramide R06528 phytoceramide amidohydrolase; Phytoceramide + H2O <=> Fatty acid + Phytosphingosine R06529 adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase; Adenosyl cobyrinate hexaamide + D-1-Aminopropan-2-ol O-phosphate + ATP <=> Adenosyl cobinamide phosphate + ADP + Orthophosphate R06530 L-threonine-O-3-phosphate carboxy-lyase; L-Threonine O-3-phosphate <=> D-1-Aminopropan-2-ol O-phosphate + CO2 R06531 ATP:L-threonine O-phosphotransferase; L-Threonine + ATP <=> L-Threonine O-3-phosphate + ADP R06532 (2R,3S)-catechin:NADP+ 4-oxidoreductase; Leucocyanidin + NADPH + H+ <=> (+)-Catechin + NADP+ + H2O R06533 (2R,3S)-gallocatechin:NADP+ 4-oxidoreductase; Leucodelphinidin + NADPH + H+ <=> (+)-Gallocatechin + NADP+ + H2O R06534 UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase; Pelargonidin + UDP-glucose <=> Pelargonidin 3-O-glucoside + UDP R06535 UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase; Cyanidin + UDP-glucose <=> Cyanidin 3-O-glucoside + UDP R06536 UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase; Delphinidin + UDP-glucose <=> Delphinidin 3-O-glucoside + UDP R06537 apigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Apigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + H2O R06538 kaempferol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Kaempferol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Quercetin + [Oxidized NADPH---hemoprotein reductase] + H2O R06539 dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase; Dihydromyricetin + 2-Oxoglutarate + Oxygen <=> Myricetin + Succinate + CO2 + H2O R06540 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; cis-3,4-Leucopelargonidin + 2-Oxoglutarate + Oxygen <=> Dihydrokaempferol + Succinate + CO2 + H2O R06541 flavan-3-ol:NADP+ oxidoreductase; (-)-Epiafzelechin + 2 NADP+ <=> Pelargonidin + 2 NADPH + H+ R06542 flavan-3-ol:NADP+ oxidoreductase; (-)-Epicatechin + 2 NADP+ <=> Cyanidin + 2 NADPH + H+ R06543 flavan-3-ol:NADP+ oxidoreductase; (-)-Epigallocatechin + 2 NADP+ <=> Delphinidin + 2 NADPH + H+ R06544 4-hydroxycinnamoyl-CoA:cyanidin-3-O-glucoside 6''-O-acyltransferase; Cyanidin 3-O-glucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + CoA R06545 4-hydroxycinnamoyl-CoA:cyanidin 3,5-O-diglucoside 6''-O-acyltransferase; Cyanidin 3,5-O-diglucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + CoA R06546 UDP-alpha-D-glucose:cyanidin-3-O-beta-D-glucoside 5-O-glucosyltransferase; Cyanidin 3-O-glucoside + UDP-glucose <=> Cyanidin 3,5-O-diglucoside + UDP R06547 UDP-alpha-D-glucose:cyanidin-3-O-(6-O-p-coumaroyl)glucoside 5-O-glucosyltransferase; Cyanidin 3-O-(6-O-p-coumaroyl)glucoside + UDP-glucose <=> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + UDP R06548 Cyanidin 3-O-glucoside <=> Peonidin 3-O-glucoside R06549 Delphinidin 3-O-glucoside <=> Petunidin 3-O-glucoside R06550 Delphinidin 3-O-glucoside <=> Malvidin 3-O-glucoside R06551 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Pentahydroxyflavanone + 2-Oxoglutarate + Oxygen <=> Tricetin + Succinate + CO2 + H2O R06553 Naringenin <=> Genistein R06554 Liquiritigenin <=> Daidzein R06556 flavanone lyase (decyclizing); Isoliquiritigenin <=> Liquiritigenin R06558 Adenosyl cobinamide + GTP <=> Adenosyl cobinamide phosphate + GDP R06560 formononetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyformononetin + [Oxidized NADPH---hemoprotein reductase] + H2O R06561 biochanin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Biochanin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxybiochanin A + [Oxidized NADPH---hemoprotein reductase] + H2O R06562 vestitone:NADP+ oxidoreductase; 2'-Hydroxyformononetin + NADPH + H+ <=> (-)-Vestitone + NADP+ R06563 ferreirin:NADP+ oxidoreductase; 2'-Hydroxybiochanin A + NADPH + H+ <=> Ferreirin + NADP+ R06564 S-adenosyl-L-methionine:daidzein 4'-O-methyltransferase; Daidzein + S-Adenosyl-L-methionine <=> Formononetin + S-Adenosyl-L-homocysteine R06565 (-)-Vestitone <=> Medicarpin R06568 malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing); p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O R06569 cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating); 5-Hydroxyferuloyl-CoA + NADPH + H+ <=> 5-Hydroxyconiferaldehyde + CoA + NADP+ R06570 cinnamyl-alcohol:NADP+ oxidoreductase; 5-Hydroxyconiferaldehyde + NADPH + H+ <=> 5-Hydroxyconiferyl alcohol + NADP+ R06571 cinnamyl-alcohol:NADP+ oxidoreductase; Caffeic aldehyde + NADPH + H+ <=> Caffeyl alcohol + NADP+ R06572 Coniferyl aldehyde + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferaldehyde + NADP+ + H2O R06573 Coniferyl alcohol + NADPH + H+ + Oxygen <=> 5-Hydroxyconiferyl alcohol + NADP+ + H2O R06574 caffeic aldehyde:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; Caffeic aldehyde + S-Adenosyl-L-methionine <=> Coniferyl aldehyde + S-Adenosyl-L-homocysteine R06575 S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; Caffeyl alcohol + S-Adenosyl-L-methionine <=> Coniferyl alcohol + S-Adenosyl-L-homocysteine R06576 S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; 5-Hydroxyconiferaldehyde + S-Adenosyl-L-methionine <=> Sinapoyl aldehyde + S-Adenosyl-L-homocysteine R06577 S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase; 5-Hydroxyconiferyl alcohol + S-Adenosyl-L-methionine <=> Sinapyl alcohol + S-Adenosyl-L-homocysteine R06578 S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase; 5-Hydroxyferuloyl-CoA + S-Adenosyl-L-methionine <=> Sinapoyl-CoA + S-Adenosyl-L-homocysteine R06579 4-Hydroxycinnamyl aldehyde <=> Caffeic aldehyde R06580 4-Coumaryl alcohol <=> Caffeyl alcohol R06582 trans-5-O-(4-coumaroyl)-D-shikimate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); 4-Coumaroylshikimate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-O-Caffeoylshikimic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R06583 4-coumarate:CoA ligase (AMP-forming); 5-Hydroxyferulic acid + CoA + ATP <=> 5-Hydroxyferuloyl-CoA + AMP + Diphosphate R06584 Feruloyl-CoA <=> 5-Hydroxyferuloyl-CoA R06586 UDP-3-ketoglucose:L-glutamate aminotransferase; UDP-3-ketoglucose + L-Glutamate <=> UDP-kanosamine + 2-Oxoglutarate R06587 UDP-kanosamine <=> Kanosamine R06588 ATP:kanosamine 6-phosphotransferase; ATP + Kanosamine <=> ADP + Kanosamine 6-phosphate R06589 Kanosamine 6-phosphate <=> Aminofructose 6-phosphate R06590 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; Aminofructose 6-phosphate + D-Ribose 5-phosphate <=> Iminoerythrose 4-phosphate + Sedoheptulose 7-phosphate R06591 phosphoenolpyruvate:imino-D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming); Iminoerythrose 4-phosphate + Phosphoenolpyruvate + H2O <=> AminoDAHP + Orthophosphate R06592 AminoDAHP <=> AminoDHQ + Orthophosphate R06593 AminoDHQ <=> 5-Amino-5-deoxy-3-dehydroshikimate + H2O R06594 UDP-glucose:NAD+ 3-oxidoreductase; UDP-glucose + NAD+ <=> UDP-3-ketoglucose + NADH + H+ R06595 5-amino-5-deoxy-3-dehydroshikimate hydro-lyase (3-amino-5-hydroxybenzoate-forming); 5-Amino-5-deoxy-3-dehydroshikimate <=> 3-Amino-5-hydroxybenzoate + H2O R06597 Proansamycin X <=> Protorifamycin I R06598 Protorifamycin I <=> Rifamycin W R06599 Proansamycin X <=> 34a-Deoxy-rifamycin W R06600 Rifamycin <=> Rifamycin B R06601 5-hydroxyisourate amidohydrolase; 5-Hydroxyisourate + H2O <=> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate R06602 isochorismate pyruvate-lyase (salicylate-forming); Isochorismate <=> Salicylate + Pyruvate R06603 Chorismate <=> Salicylate + Pyruvate R06604 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate carboxy-lyase [(S)-allantoin-forming]; 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)-Allantoin + CO2 R06605 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)(-)-Allantoin + CO2 R06606 daidzein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Daidzein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxydaidzein + [Oxidized NADPH---hemoprotein reductase] + H2O R06607 genistein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Genistein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxygenistein + [Oxidized NADPH---hemoprotein reductase] + H2O R06610 (2S)-flavan-4-ol:NADP+ 4-oxidoreductase; cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase; Naringenin + NADPH + H+ <=> Apiforol + NADP+ R06611 UDPglucose:flavonol 3-O-D-glucosyltransferase; Kaempferol + UDP-glucose <=> Kaempferol 3-O-glucoside + UDP R06612 5,6-Indolequinone-2-carboxylic acid <=> Eumelanin R06613 5,10-methylenetetrahydrofolate,NADPH:dUMP C-methyltransferase; 5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ <=> Tetrahydrofolate + dTMP + NADP+ R06614 3-cyano-L-alanine carboxy-lyase (3-aminopropiononitrile-forming); 3-Cyano-L-alanine <=> 3-Aminopropiononitrile + CO2 R06615 (2R,3S)-afzelechin:NADP+ 4-oxidoreductase; cis-3,4-Leucopelargonidin + NADPH + H+ <=> Afzelechin + NADP+ + H2O R06617 Gibberellin A4 <=> Gibberellin A7 R06618 Gibberellin A7 <=> Gibberellin A3 R06619 Gibberellin A4 <=> Gibberellin A1 R06620 D-glucose:ubiquinone oxidoreductase; D-Glucose + Ubiquinone <=> D-Glucono-1,5-lactone + Ubiquinol R06621 cis-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH R06622 NADPH + 2-Hydroxycyclohexan-1-one + H+ + Oxygen <=> NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O R06623 glycoprotein-phosphatidylinositol phosphatidohydrolase; G00144 + H2O <=> 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate R06624 3,5-dihydroxyphenylacetyl-CoA:oxygen oxidoreductase (3,5-dihydroxyphenylglyoxylate-forming); 3,5-Dihydroxyphenylacetyl-CoA + Oxygen <=> 3,5-Dihydroxyphenylglyoxylate + CoA R06625 malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming); 4 Malonyl-CoA <=> 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O R06626 4-Hydroxyphenylglyoxylate + L-Tyrosine <=> L-4-Hydroxyphenylglycine + 3-(4-Hydroxyphenyl)pyruvate R06627 dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + S-Adenosyl-L-methionine <=> dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose + S-Adenosyl-L-homocysteine R06628 dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose 5-epimerase; dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose <=> dTDP-L-4-oxovancosamine R06629 dTDP-L-4-oxovancosamine + NADPH + H+ <=> dTDP-L-epivancosamine + NADP+ R06630 dTDP-L-4-oxovancosamine <=> dTDP-L-vancosamine R06631 dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose:2-oxoglutarate aminotransferase; dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + L-Glutamate <=> dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-Oxoglutarate R06632 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating); 3-(4-Hydroxyphenyl)pyruvate + Oxygen <=> (S)-4-Hydroxymandelate + CO2 R06633 (S)-4-hydroxymandelate:oxygen 1-oxidoreductase; (S)-4-Hydroxymandelate + Oxygen <=> 4-Hydroxyphenylglyoxylate + Hydrogen peroxide R06634 (S)-3,5-dihydroxyphenylglycine:2-oxoglutarate aminotransferase; 3,5-Dihydroxy-phenylglycine + 2-Oxoglutarate <=> 3,5-Dihydroxyphenylglyoxylate + L-Glutamate R06635 Acetyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 7 CO2 + 7 CoA R06637 Butanoyl-CoA + 7 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-octadecanoyl-[acp] + 7 CO2 + 7 CoA R06641 Malonamoyl-CoA + 8 Malonyl-CoA + Acyl-carrier protein <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 9 CoA R06642 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9 Reduced nonaketamide + NADP+ R06643 10 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] + 10 CO2 + 10 CoA R06644 Propanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] + 9 CO2 + 9 CoA R06645 Butanoyl-CoA + 9 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15,17,19-Nonaoxo-docosanoyl-[acp] + 9 CO2 + 9 CoA R06650 Tetrangomycin <=> Tetrangulol + H2O R06651 Tetrangulol <=> 8-O-Methyltetrangulol R06652 8-O-Methyltetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol R06653 Tetrangulol <=> 19-Hydroxytetrangulol R06654 19-Hydroxytetrangulol <=> 19-Hydroxy-8-O-methyltetrangulol R06655 19-Hydroxy-8-O-methyltetrangulol <=> PD116740 R06656 Tetrangomycin <=> Rabelomycin R06659 Urdamycinone B + dTDP-beta-L-rhodinose <=> 100-1 + dTDP R06660 dTDP-D-olivose:compound-100-1 O-beta-D-olivosyltransferase; 100-1 + dTDP-D-olivose <=> Urdamycin B + dTDP R06661 Urdamycinone B <=> 104-2 R06662 104-2 + dTDP-beta-L-rhodinose + dTDP-D-olivose <=> 124-1 + 2 dTDP R06664 Urdamycinone F + 2 dTDP-beta-L-rhodinose + dTDP-D-olivose <=> Urdamycin F + 3 dTDP R06665 Urdamycinone F <=> Aquayamycin + H2O R06666 Aquayamycin + dTDP-beta-L-rhodinose <=> 100-2 + dTDP R06667 100-2 + dTDP-beta-L-rhodinose <=> Urdamycin G + dTDP R06668 dTDP-D-olivose:urdamycin-G D-olivosyltransferase; Urdamycin G + dTDP-D-olivose <=> Urdamycin A + dTDP R06670 Jadomycin A <=> Jadomycin B R06671 Dehydrorabelomycin <=> Kinobscurinone R06672 Kinobscurinone <=> Stealthin C R06673 Stealthin C <=> Prekinamycin R06674 Prekinamycin <=> Kinamycin D R06675 S-adenosyl-L-methionine:nogalonic-acid O-methyltransferase; Nogalonate + S-Adenosyl-L-methionine <=> Methyl nogalonate + S-Adenosyl-L-homocysteine R06676 auraviketone lyase (decyclizing); Methyl nogalonate <=> Auraviketone R06677 auramycinone:NADP+ 7-oxidoreductase; Auraviketone + NADPH + H+ <=> Auramycinone + NADP+ R06678 Methyl nogalonate <=> Dihydro-NAME R06679 12-deoxyaklanonic-acid:oxygen oxidoreductase; 12-Deoxyaklanonic acid + Oxygen <=> Aklanonate + H2O R06680 S-adenosyl-L-methionine:aklanonate O-methyltransferase; Aklanonate + S-Adenosyl-L-methionine <=> Methyl aklanonate + S-Adenosyl-L-homocysteine R06681 aklaviketone lyase (ring-opening); methyl aklanonate cyclase; Methyl aklanonate <=> Aklaviketone R06682 aklavinone:NADP+ 7-oxidoreductase; Aklaviketone + NADPH + H+ <=> Aklavinone + NADP+ R06683 aklavinone,NADPH:oxygen oxidoreductase (12-hydroxylating); Aklavinone + NADPH + H+ + Oxygen <=> epsilon-Rhodomycinone + NADP+ + H2O R06684 dTDP-beta-L-daunosamine:epsilon-rhodomycinone beta-L-daunosaminyltransferase; epsilon-Rhodomycinone + dTDP-beta-L-daunosamine <=> Rhodomycin D + dTDP R06685 Rhodomycin D + H2O <=> 10-Carboxy-13-deoxycarminomycin + Methanol R06686 10-Carboxy-13-deoxycarminomycin <=> 13-Deoxycarminomycin + CO2 R06687 S-adenosyl-L-methionine:13-deoxycarminomycin 4-O-methyltransferase; 13-Deoxycarminomycin + S-Adenosyl-L-methionine <=> 13-Deoxydaunorubicin + S-Adenosyl-L-homocysteine R06688 13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating); 13-Deoxydaunorubicin + NADPH + H+ + Oxygen <=> 13-Dihydrodaunorubicin + NADP+ + H2O R06689 13-dihydrodaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating); 13-Dihydrodaunorubicin + NADPH + H+ + Oxygen <=> Daunorubicin + NADP+ + 2 H2O R06690 daunorubicin,NADPH:oxygen oxidoreductase (hydroxylating); Daunorubicin + NADPH + H+ + Oxygen <=> Doxorubicin + NADP+ + H2O R06691 13-deoxycarminomycin,NADPH:oxygen oxidoreductase (13-hydroxylating); 13-Deoxycarminomycin + NADPH + H+ + Oxygen <=> 13-Dihydrocarminomycin + NADP+ + H2O R06692 13-dihydrocarminomycin,NADPH:oxygen oxidoreductase; 13-Dihydrocarminomycin + NADPH + H+ + Oxygen <=> Carminomycin + NADP+ + 2 H2O R06693 S-adenosyl-L-methionine:carminomycin 4-O-methyltransferase; Carminomycin + S-Adenosyl-L-methionine <=> Daunorubicin + S-Adenosyl-L-homocysteine R06694 Daunorubicin <=> (13S)-13-Dihydrodaunorubicin R06695 (S)-DNPA <=> 6-Deoxydihydrokalafungin R06696 6-Deoxydihydrokalafungin + Oxygen <=> Dihydrokalafungin + H2O R06697 2 DHKred-OH <=> Actinorhodin R06698 Dihydrokalafungin <=> Medermycin R06699 tetracenomycin-F2 hydro-lyase (tetracenomycin-F1-forming); Tetracenomycin F2 <=> Tetracenomycin F1 + H2O R06700 tetracenomycin-F1:oxygen C5-monooxygenase; Tetracenomycin F1 + Oxygen <=> Tetracenomycin D3 + H2O R06701 Tetracenomycin D3 <=> Tetracenomycin B3 R06702 Tetracenomycin B3 <=> Tetracenomycin E R06703 S-adenosyl-L-methionine:tetracenomycin-E O-methyltransferase; Tetracenomycin E + S-Adenosyl-L-methionine <=> Tetracenomycin A2 + S-Adenosyl-L-homocysteine R06704 tetracenomycin-A2,NADPH:oxygen oxidoreductase (tetracenomycin-C-forming); Tetracenomycin A2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> Tetracenomycin C + 2 NADP+ + 2 H2O R06706 Tetracenomycin F1 <=> Tetracenomycin F1 methylester R06707 Tetracenomycin F1 <=> Decarboxytetracenomycin F1 R06709 Tetracenomycin D3 <=> Tetracenomycin D3 methylester R06710 Tetracenomycin D3 <=> Tetracenomycin D1 R06711 Tetracenomycin B3 <=> Tetracenomycin B1 R06713 S-adenosyl-L-methionine:tetracenomycin-B3 O-methyltransferase; S-Adenosyl-L-methionine + Tetracenomycin B3 <=> S-Adenosyl-L-homocysteine + Tetracenomycin B2 R06714 Tetracenomycin A2 <=> Tetracenomycin X R06715 S-adenosyl-L-methionine:4-demethylpremithramycinone O-methyltransferase; 4-Demethylpremithramycinone + S-Adenosyl-L-methionine <=> Premithramycinone + S-Adenosyl-L-homocysteine R06716 dTDP-D-olivose:premithramycinone D-olivosyltransferase; Premithramycinone + dTDP-D-olivose <=> Premithramycin A1 + dTDP R06717 dTDP-D-oliose:premithramycin-A1 D-oliosyltransferase; Premithramycin A1 + dTDP-D-oliose <=> Premithramycin A2' + dTDP R06718 Premithramycin A2' + dTDP-D-mycarose <=> Premithramycin A3' + dTDP R06719 S-adenosyl-L-methionine:premithramycin-A3' C-methyltransferase; Premithramycin A3' + S-Adenosyl-L-methionine <=> Premithramycin A3 + S-Adenosyl-L-homocysteine R06722 alpha 1,2-mannosyloligosaccharide alpha-D-mannohydrolase; H2O + G00011 <=> D-Mannose + G10694 R06724 sym-Homospermidine <=> Trachelanthamidine R06725 Trachelanthamidine <=> Retronecine R06726 Retronecine + 2 L-Isoleucine <=> Senecionine R06727 1-Methylpyrrolinium + Benzoate <=> Cocaine R06728 cocaine benzoylhydrolase; Cocaine + H2O <=> Ecgonine methyl ester + Benzoate R06729 Ecgonine methyl ester + H2O <=> Ecgonine + Methanol R06730 Ecgonine <=> Pseudoecgonine R06731 Pseudoecgonine + ATP + CoA <=> Pseudoecgonyl-CoA + AMP R06732 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate <=> Hygrine R06733 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate <=> Tropinone R06734 pseudotropine:NADP+ 3-oxidoreductase; Tropinone + NADPH + H+ <=> Pseudotropine + NADP+ R06735 acetyl-CoA:tropine O-acetyltransferase; Acetyl-CoA + Tropine <=> CoA + Acetyltropine R06736 acetyl-CoA:pseudotropine O-acetyltransferase; Acetyl-CoA + Pseudotropine <=> CoA + Acetylpseudotropine R06737 Pseudotropine <=> Calystegin A3 R06738 Nicotine <=> Nornicotine R06740 Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide R06741 5-Aminopentanal <=> Piperideine R06743 Anabasine <=> Anatalline R06744 L-Phenylalanine <=> Tropate R06745 trans-Cinnamate <=> Cocaine R06746 L-proline:[peptidyl-carrier protein] ligase (AMP-forming); L-Proline + Peptidyl-carrier protein + ATP <=> L-Prolyl-[pcp] + AMP + Diphosphate R06747 L-prolyl-[peptidyl-carrier protein]:electron-transfer flavoprotein oxidoreductase; L-Prolyl-[pcp] + 2 Electron-transferring flavoprotein <=> Pyrrole-2-carbonyl-[pcp] + 2 Reduced electron-transferring flavoprotein R06748 pyrrole-2-carbonyl-[peptidyl-carrier protein]:[peptidyl-carrier protein] (pyrrole-2-carbonyl)transferase; Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein <=> Pyrrole-2-carbonyl-[pcp] + Peptidyl-carrier protein R06751 L-Tyrosine + Peptidyl-carrier protein + ATP <=> L-Tyrosyl-[pcp] + AMP + Diphosphate R06752 L-Tyrosyl-[pcp] + Oxygen <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O R06753 beta-Hydroxy-L-tyrosyl-[pcp] <=> beta-Keto-L-tyrosyl-[pcp] R06757 dimethylallyl diphosphate:4-hydroxyphenylpyruvate 3-dimethylallyltransferase; 3-(4-Hydroxyphenyl)pyruvate + Dimethylallyl diphosphate <=> 3-Dimethylallyl-4-hydroxyphenylpyruvate + Diphosphate R06758 3-(4-hydroxy-3-prenylphenyl)pyruvate:oxygen 1,2-oxidoreductase (4-hydroxy-3-prenylmandelate-forming); 3-Dimethylallyl-4-hydroxyphenylpyruvate + Oxygen <=> 3-Dimethylallyl-4-hydroxymandelic acid + CO2 R06759 4-hydroxy-3-prenylmandelate:oxygen oxidoreductase (4-hydroxy-3-prenylbenzoate forming); 3-Dimethylallyl-4-hydroxymandelic acid + Oxygen <=> 3-Dimethylallyl-4-hydroxybenzoate + CO2 + H2O R06760 beta-Hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp] R06761 3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp] <=> 3-Dimethylallyl-4-hydroxybenzaldehyde R06762 3-Dimethylallyl-4-hydroxyphenylpyruvate <=> 3-Dimethylallyl-4-hydroxybenzaldehyde R06763 3-Dimethylallyl-4-hydroxybenzaldehyde <=> 3-Dimethylallyl-4-hydroxybenzoate R06764 beta-Keto-L-tyrosyl-[pcp] <=> 2-Hydroxy-beta-keto-L-tyrosyl-[pcp] R06765 2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <=> 3-Amino-4,7-dihydroxycoumarin R06766 3-Amino-4,7-dihydroxycoumarin <=> 3-Amino-4,7-dihydroxy-8-chlorocoumarin R06767 Coumermic acid + 2 dTDP-5-dimethyl-L-lyxose + 2 S-Adenosyl-L-methionine <=> Coumermycin D + 2 dTDP + 2 S-Adenosyl-L-homocysteine R06768 Coumermycin D + 2 Pyrrole-2-carbonyl-[pcp] <=> Coumermycin A1 R06770 dTDP-4-O-demethyl-beta-L-noviose:novobiocic-acid 7-O-[4-O-demethyl-L-noviosyl]transferase; Novobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Demethyldecarbamoylnovobiocin + dTDP R06771 S-adenosyl-L-methionine:demethyldecarbamoylnovobiocin 4''-O-methyltransferase; Demethyldecarbamoylnovobiocin + S-Adenosyl-L-methionine <=> Decarbamoylnovobiocin + S-Adenosyl-L-homocysteine R06772 carbamoyl phosphate:decarbamoylnovobiocin 3''-O-carbamoyltransferase; Decarbamoylnovobiocin + Carbamoyl phosphate <=> Novobiocin + Orthophosphate R06773 Chlorobiocic acid + dTDP-5-dimethyl-L-lyxose <=> Novclobiocin 105 + dTDP R06774 Novclobiocin 105 + S-Adenosyl-L-methionine <=> Novclobiocin 104 + S-Adenosyl-L-homocysteine R06775 Novclobiocin 104 + Pyrrole-2-carbonyl-[pcp] <=> Clorobiocin R06776 3-Amino-4,7-dihydroxy-8-chlorocoumarin + 3-Dimethylallyl-4-hydroxybenzoate <=> Chlorobiocic acid R06777 3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate R06778 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + 3-Amino-4,7-dihydroxycoumarin + ATP + 2 S-Adenosyl-L-methionine <=> Coumermic acid + AMP + Diphosphate + 2 S-Adenosyl-L-homocysteine R06779 Nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2 R06780 Phenylpropanoate <=> 3-(3-Hydroxyphenyl)propanoic acid R06781 trans-Cinnamate <=> trans-3-Hydroxycinnamate R06782 3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating); Phenylpropanoate + Oxygen + NADH + H+ <=> cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+ R06783 trans-cinnamate,NADH:oxygen oxidoreductase (2,3-hydroxylating); trans-Cinnamate + Oxygen + NADH + H+ <=> cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+ R06784 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate:NAD+ oxidoreductase; cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol + NAD+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + NADH + H+ R06785 (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate:NAD+ oxidoreductase; cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+ <=> trans-2,3-Dihydroxycinnamate + NADH + H+ R06786 3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating); 3-(3-Hydroxyphenyl)propanoic acid + Oxygen + NADH + H+ <=> 3-(2,3-Dihydroxyphenyl)propanoate + H2O + NAD+ R06787 (2E)-3-(3-hydroxyphenyl)prop-2-enoate,NADH:oxygen oxidoreductase (2-hydroxylating); trans-3-Hydroxycinnamate + Oxygen + NADH + H+ <=> trans-2,3-Dihydroxycinnamate + H2O + NAD+ R06788 (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate:oxygen 1,2-oxidoreductase (decyclizing); trans-2,3-Dihydroxycinnamate + Oxygen <=> 2-Hydroxy-6-ketononatrienedioate R06789 (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate fumarylhydrolase; 2-Hydroxy-6-ketononatrienedioate + H2O <=> 2-Hydroxy-2,4-pentadienoate + Fumarate R06790 Phenylacetic acid <=> 4-Hydroxyphenylacetate R06791 Phenylacetic acid <=> 3-Hydroxyphenylacetate R06792 Apigenin + 2 NADPH + 2 H+ + Oxygen <=> 2-Hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O R06793 2-hydroxy-2,3-dihydrogenistein hydro-lyase (genistein-forming); 2-Hydroxy-2,3-dihydrogenistein <=> Genistein + H2O R06794 S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase; Genistein + S-Adenosyl-L-methionine <=> Prunetin + S-Adenosyl-L-homocysteine R06795 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; Biochanin A + UDP-glucose <=> Biochanin A-beta-D-glucoside + UDP R06796 malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Biochanin A-beta-D-glucoside + Malonyl-CoA <=> Biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) + CoA R06797 malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase; Isoquercitrin + Malonyl-CoA <=> Quercetin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA R06798 Pelargonidin 3-O-glucoside <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside R06799 malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase; Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + Malonyl-CoA <=> 4'''-Demalonylsalvianin + CoA R06800 malonyl-CoA:4'''-demalonylsalvianin 4'''-O-malonyltransferase; 4'''-Demalonylsalvianin + Malonyl-CoA <=> Salvianin + CoA R06801 malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase; Pelargonidin 3-O-glucoside + Malonyl-CoA <=> Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA R06802 Pelargonidin 3-O-glucoside + UDP-L-rhamnose <=> Pelargonidin 3-O-rutinoside + UDP R06803 UDP-glucose:pelargonidin 3-O-rutinoside 5-O-beta-D-glucosyltransferase; Pelargonidin 3-O-rutinoside + UDP-glucose <=> Pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP R06804 UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase; Kaempferol 3-O-glucoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP R06805 UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase; Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Kaempferol 3-sophorotrioside + UDP R06806 4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase; Kaempferol 3-sophorotrioside + p-Coumaroyl-CoA <=> Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA R06807 S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase; Kaempferol + S-Adenosyl-L-methionine <=> Kaempferide + S-Adenosyl-L-homocysteine R06808 UDP-alpha-D-galactose:kaempferol 3-O-beta-D-galactosyltransferase; Kaempferol + UDP-alpha-D-galactose <=> Kaempferol-3-O-galactoside + UDP R06809 3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase; Quercetin 3,4'-bissulfate + 3'-Phosphoadenylyl sulfate <=> Quercetin 3,4',7-trissulfate + Adenosine 3',5'-bisphosphate R06810 UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase; Quercetin + UDP-glucose <=> Quercimeritrin + UDP R06811 UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase; Rutin + UDP-D-xylose <=> Quercetin 3-(2G-xylosylrutinoside) + UDP R06812 UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase; Isoquercitrin + UDP-glucose <=> Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP R06813 UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase; Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-glucose <=> Quercetin 3-sophorotrioside + UDP R06814 UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase; Isoquercitrin + UDP-D-xylose <=> Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside] + UDP R06815 S-adenosyl-L-methionine:myricetin O-methyltransferase; Myricetin + S-Adenosyl-L-methionine <=> Laricitrin + S-Adenosyl-L-homocysteine R06816 S-adenosyl-L-methionine:myricetin O-methyltransferase; Laricitrin + S-Adenosyl-L-methionine <=> Syringetin + S-Adenosyl-L-homocysteine R06817 malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase; Cyanidin 3-O-glucoside + Malonyl-CoA <=> Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA R06818 Cyanidin 3-O-glucoside + UDP-L-rhamnose <=> Cyanidin 3-O-rutinoside + UDP R06819 UDP-glucose:cyanidin 3-O-rutinoside 5-O-beta-D-glucosyltransferase; Cyanidin 3-O-rutinoside + UDP-glucose <=> Cyanidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP R06820 UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-alpha-L-rhamnosyltransferase; Naringenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Naringin + UDP R06821 malonyl-CoA:flavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Apigenin 7-O-beta-D-glucoside + Malonyl-CoA <=> Apigenin 7-(6''-malonylglucoside) + CoA R06822 Apigenin <=> Vitexin R06823 Vitexin <=> Vitexin 2''-O-beta-L-rhamnoside R06824 S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase; Vitexin 2''-O-beta-L-rhamnoside + S-Adenosyl-L-methionine <=> Isoswertisin 2''-rhamnoside + S-Adenosyl-L-homocysteine R06825 Apigenin <=> Isovitexin R06826 UDP-L-rhamnose:apigenin 7-O-beta-D-glucoside 2''-O-beta-L-rhamnosyltransferase; Apigenin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Apigenin 7-O-neohesperidoside + UDP R06827 UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase; Luteolin 7-O-glucuronide + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP R06828 UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase; Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + UDP-glucuronate <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + UDP R06829 UDP-L-rhamnose:luteolin-7-O-beta-D-glucoside 2''-O-alpha-L-rhamnosyltransferase; Luteolin 7-O-beta-D-glucoside + UDP-L-rhamnose <=> Scolymoside + UDP R06830 2-Aminomalonate semialdehyde <=> Aminoacetaldehyde + CO2 R06831 1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating); 1,2,4-Trichlorobenzene + NADH + H+ + Oxygen <=> 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ R06832 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase; 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3,4,6-Trichlorocatechol + NADH + H+ R06833 catechol:oxygen 1,2-oxidoreductase; 3,4,6-Trichlorocatechol + Oxygen <=> 2,3,5-Trichloro-cis,cis-muconate R06834 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase; 2,3,5-Trichloro-cis,cis-muconate <=> 2,5-Dichloro-carboxymethylenebut-2-en-4-olide + Hydrochloric acid R06835 4-carboxymethylenebut-2-en-4-olide lactonohydrolase; 2,5-Dichloro-carboxymethylenebut-2-en-4-olide + H2O <=> 2,5-Dichloro-4-oxohex-2-enedioate R06836 ATP:ribose-1,5-bisphosphate phosphotransferase; D-Ribose 1,5-bisphosphate + ATP <=> 5-Phospho-alpha-D-ribose 1-diphosphate + ADP R06837 ribose 1-phosphokinase; alpha-D-Ribose 1-phosphate <=> D-Ribose 1,5-bisphosphate R06838 4-carboxymethylenebut-2-en-4-olide lactonohydrolase; trans-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate R06839 catechol:oxygen 1,2-oxidoreductase; 3-Chlorocatechol + Oxygen <=> 2-Chloro-cis,cis-muconate R06840 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); 2-Chloro-cis,cis-muconate <=> trans-4-Carboxymethylenebut-2-en-4-olide + Hydrochloric acid R06846 L-quinate:NADP+ 3-oxidoreductase; Quinate + NADP+ <=> 3-Dehydroquinate + NADPH + H+ R06847 shikimate:NAD+ 3-oxidoreductase; Shikimate + NAD+ <=> 3-Dehydroshikimate + NADH + H+ R06848 3-oxoadipate:NAD(P)+ oxidoreductase; 2,5-Dichloro-4-oxohex-2-enedioate + 2 NADH + 2 H+ <=> 2-Chloro-3-oxoadipate + Hydrochloric acid + 2 NAD+ R06849 1,2,4-Trichlorobenzene <=> 1,4-Dichlorobenzene R06850 1,4-Dichlorobenzene <=> Chlorobenzene R06851 Hydroquinone + NADPH + H+ + Oxygen <=> Benzene-1,2,4-triol + NADP+ + H2O R06852 4-Hydroxyaniline + H2O <=> p-Benzoquinone + Ammonia R06853 Benzene-1,2,4-triol <=> 2-Hydroxy-1,4-benzoquinone R06854 2-Hydroxy-1,4-benzoquinone <=> p-Benzoquinone + H2O R06855 2-Chloro-3-oxoadipate <=> Chloroacetic acid + Succinate R06856 chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating); Chlorobenzene + Oxygen + NADH + H+ <=> 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ R06857 (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase; 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 3-Chlorocatechol + NADH + H+ R06861 D-xylulose-5-phosphate:thiamin diphosphate glycolaldehydetransferase; alpha,beta-dihydroxyethyl-TPP:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; D-Xylulose 5-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Glyceraldehyde 3-phosphate R06862 alpha,beta-dihydroxyethyl-TPP:formaldehyde glycolaldehydetransferase; alpha,beta-Dihydroxyethyl-TPP + Formaldehyde <=> Thiamin diphosphate + Glycerone R06863 D-sedoheptulose-7-phosphate:thiamin diphosphate glycolaldehydetransferase; Sedoheptulose 7-phosphate + Thiamin diphosphate <=> alpha,beta-Dihydroxyethyl-TPP + D-Ribose 5-phosphate R06865 3-Hexaprenyl-4-hydroxybenzoate + Oxygen <=> 3-Hexaprenyl-4,5-dihydroxybenzoate + H2O R06866 3-Hexaprenyl-4-hydroxy-5-methoxybenzoate <=> 2-Hexaprenyl-6-methoxyphenol + CO2 R06867 UDP-sulfoquinovose:diacylglycerol alpha-D-sulfoquinovosyltransferase; UDP-6-sulfoquinovose + 1,2-Diacyl-sn-glycerol <=> Sulfoquinovosyldiacylglycerol + UDP R06868 S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase; S-Adenosyl-L-methionine + N-Methylethanolamine phosphate <=> S-Adenosyl-L-homocysteine + Phosphodimethylethanolamine R06869 S-adenosyl-L-methionine:phosphodimethylethanolamine N-methyltransferase; S-Adenosyl-L-methionine + Phosphodimethylethanolamine <=> S-Adenosyl-L-homocysteine + Choline phosphate R06870 phosphoethanolamine phosphohydrolase; Ethanolamine phosphate + H2O <=> Ethanolamine + Orthophosphate R06871 phosphocholine phosphohydrolase; Choline phosphate + H2O <=> Choline + Orthophosphate R06872 acyl-CoA:sn-glycerol-3-phosphate 2-O-acyltransferase; sn-Glycerol 3-phosphate + Acyl-CoA <=> 2-Acyl-sn-glycerol 3-phosphate + CoA R06875 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate 3-phosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate R06876 Tetrabromobisphenol A <=> Tribromobisphenol A + Hydrobromic acid R06877 Tribromobisphenol A <=> Dibromobisphenol A + Hydrobromic acid R06878 Dibromobisphenol A <=> Monobromobisphenol A + Hydrobromic acid R06879 Monobromobisphenol A <=> Bisphenol A + Hydrobromic acid R06880 2 Bisphenol A <=> 4-Methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene R06881 Bisphenol A <=> 5-Hydroxybisphenol A R06882 5-Hydroxybisphenol A <=> 4,5-Bisphenol-o-quinone R06883 Bisphenol A + NADH + H+ + Oxygen <=> 1,2-Bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O R06884 Bisphenol A + NADH + H+ + Oxygen <=> 2,2-Bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O R06885 1,2-Bis(4-hydroxyphenyl)-2-propanol <=> 4,4'-Dihydroxy-alpha-methylstilbene + H2O R06886 4,4'-Dihydroxy-alpha-methylstilbene + Oxygen <=> 4-Hydroxybenzaldehyde + 4'-Hydroxyacetophenone R06887 2,2-Bis(4-hydroxyphenyl)-1-propanol <=> 2,2-Bis(4-hydroxyphenyl)-propanoic acid R06888 2,2-Bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + Oxygen <=> 2,3-Bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O R06889 2,3-Bis(4-hydroxyphenyl)-1,2-propanediol <=> 4-Hydroxyphenacyl alcohol + 4-Hydroxybenzoate R06890 4-Ethylphenol + NADPH + H+ + Oxygen <=> 1-(4'-Hydroxyphenyl)ethanol + NADP+ + H2O R06891 1-(4'-Hydroxyphenyl)ethanol + NAD+ <=> 4'-Hydroxyacetophenone + NADH + H+ R06892 (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming); 4'-Hydroxyacetophenone + NADPH + H+ + Oxygen <=> 4-Hydroxyphenyl acetate + NADP+ + H2O R06893 aryl-ester hydrolase; 4-Hydroxyphenyl acetate + H2O <=> Hydroquinone + Acetate R06894 UDP-N-acetyl-D-galactosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-D-galactosaminuronic acid + 2 NADH + 2 H+ R06895 coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase(decarboxylating); Coproporphyrinogen III + 2 S-Adenosyl-L-methionine <=> Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine R06896 chlorophyllide-a:NADP+ oxidoreductase; Divinylprotochlorophyllide + NADPH + H+ <=> Protochlorophyllide + NADP+ R06897 2,4-dihydroxyhept-2-enedioate hydro-lyase; 2-Hydroxyhepta-2,4-dienedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate R06898 2-Naphthoic acid <=> 5,6,7,8-Tetrahydro-2-naphthoic acid R06899 5,6,7,8-Tetrahydro-2-naphthoic acid <=> Decahydro-2-naphthoic acid R06900 5,6,7,8-Tetrahydro-2-naphthoic acid <=> cis-2-Carboxycyclohexyl-acetic acid R06901 Tetralin <=> 5,6,7,8-Tetrahydro-2-naphthoic acid R06902 2-Naphthoic acid + FADH2 + Oxygen <=> 1-Hydroxy-2-naphthoate + FAD + H2O R06903 2-Methylnaphthalene + Fumarate <=> 2-Naphtylmethylsuccinic acid R06904 2-Naphtylmethylsuccinic acid + Succinyl-CoA <=> Naphthyl-2-methyl-succinyl-CoA + Succinate R06905 Naphthyl-2-methyl-succinyl-CoA <=> Naphthyl-2-methylene-succinyl-CoA + 2 H+ R06906 Naphthyl-2-methylene-succinyl-CoA + H2O <=> Naphthyl-2-hydroxymethyl-succinyl CoA R06907 Naphthyl-2-hydroxymethyl-succinyl CoA <=> Naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ R06908 Naphthyl-2-oxomethyl-succinyl-CoA + CoA <=> 2-Naphthoyl-CoA + Succinyl-CoA R06909 naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating); 1-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ R06910 cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase; cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ <=> 1,2-Dihydroxy-8-methylnaphthalene + NADH + H+ R06911 1,2-Dihydroxy-8-methylnaphthalene + Oxygen <=> 2-Hydroxy-8-methylchromene-2-carboxylate R06912 2-Hydroxy-8-methylchromene-2-carboxylate <=> 2-Hydroxy-3-methylbenzalpyruvate R06913 2-Hydroxy-3-methylbenzalpyruvate + H2O <=> 3-Methylsalicylaldehyde + Pyruvate R06914 3-Methylsalicylaldehyde + NAD+ + H2O <=> 3-Methylsalicylate + NADH + H+ R06915 salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating); 3-Methylsalicylate + Oxygen + NADH + H+ <=> 2,3-Dihydroxytoluene + NAD+ + CO2 + H2O R06916 1-Methylnaphthalene + Oxygen + NADH + H+ <=> 1-Hydroxymethylnaphthalene + NAD+ + H2O R06917 1-hydroxymethylnaphthalene:NAD+ oxidoreductase; 1-Hydroxymethylnaphthalene + NAD+ <=> 1-Naphthaldehyde + NADH + H+ R06918 1-Naphthaldehyde + NAD+ + H2O <=> 1-Naphthoic acid + NADH + H+ R06919 1-Naphthoic acid + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+ R06920 cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene <=> 1,2-Dihydroxy-8-carboxynaphthalene R06921 1,2-Dihydroxy-8-carboxynaphthalene + Oxygen <=> 2-Carboxy-2-hydroxy-8-carboxychromene R06922 2-Carboxy-2-hydroxy-8-carboxychromene <=> 2-Hydroxy-3-carboxybenzalpyruvate R06923 2-Hydroxy-3-carboxybenzalpyruvate + H2O <=> 3-Formylsalicylic acid + Pyruvate R06924 3-Formylsalicylic acid + Oxygen + H2O <=> 2-Hydroxyisophthalic acid + Hydrogen peroxide R06925 2-Hydroxyisophthalic acid <=> Salicylate + CO2 R06926 2-Methylnaphthalene + Oxygen + NADH + H+ <=> (2-Naphthyl)methanol + NAD+ + H2O R06927 (2-naphthyl)methanol:NAD+ oxidoreductase; (2-Naphthyl)methanol + NAD+ <=> 2-Naphthaldehyde + NADH + H+ R06928 2-Naphthaldehyde + NAD+ + H2O <=> 2-Naphthoic acid + NADH + H+ R06929 2-Naphthaldehyde <=> 4-Formylsalicylic acid R06930 naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating); (2-Naphthyl)methanol + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+ R06931 cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase; cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene + NAD+ <=> 1,2-Dihydroxy-7-hydroxymethylnaphthalene + NADH + H+ R06932 1,2-Dihydroxy-7-hydroxymethylnaphthalene + Oxygen <=> 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate R06933 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate <=> 2-Hydroxy-4-hydroxymethylbenzalpyruvate R06934 2-Hydroxy-4-hydroxymethylbenzalpyruvate + H2O <=> 4-Hydroxymethylsalicylaldehyde + Pyruvate R06935 4-Hydroxymethylsalicylaldehyde + NAD+ + H2O <=> 4-Hydroxymethylsalicylate + NADH + H+ R06936 salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating); 4-Hydroxymethylsalicylate + Oxygen + NADH + H+ <=> 4-Hydroxymethylcatechol + NAD+ + H2O + CO2 R06937 naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating); 2-Methylnaphthalene + Oxygen + NADH + H+ <=> cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene + NAD+ R06938 cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene <=> 4-Methylsalicylate R06939 salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating); 4-Methylsalicylate + Oxygen + NADH + H+ <=> 4-Methylcatechol + NAD+ + H2O + CO2 R06940 N-Cyclohexylformamide + H2O <=> Cyclohexylamine + Formate R06941 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase; (3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+ R06942 (3S)-3-hydroxyacyl-CoA hydro-lyase; 5-Carboxy-2-pentenoyl-CoA + H2O <=> (3S)-3-Hydroxyadipyl-CoA R06943 Adipyl-CoA + FAD <=> 5-Carboxy-2-pentenoyl-CoA + FADH2 R06944 Adipate + CoA + ATP <=> Adipyl-CoA + AMP + Diphosphate R06945 Cyclohexane + Oxygen + NADH + H+ <=> Cyclohexanol + NAD+ + H2O R06946 zeaxanthin,NADH:oxygen oxidoreductase; Zeaxanthin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Antheraxanthin + 2 Oxidized ferredoxin + H2O R06947 zeaxanthin,NADH:oxygen oxidoreductase; Antheraxanthin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Violaxanthin + 2 Oxidized ferredoxin + H2O R06948 violaxanthin-neoxanthin isomerase (epoxide-opening); Violaxanthin <=> Neoxanthin R06949 Neoxanthin <=> 9'-cis-Neoxanthin R06950 Violaxanthin <=> 9-cis-Violaxanthin R06951 violaxanthin-neoxanthin isomerase (epoxide-opening); 9-cis-Violaxanthin <=> 9'-cis-Neoxanthin R06952 9'-cis-neoxanthin:9-cis-epoxycarotenoid dioxygenase; 9'-cis-Neoxanthin + Oxygen <=> Xanthoxin + C25-Allenic-apo-aldehyde R06953 9-cis-violaxanthin:9-cis-epoxycarotenoid dioxygenase; 9-cis-Violaxanthin + Oxygen <=> Xanthoxin + C25-Epoxy-apo-aldehyde R06954 xanthoxin:NAD+ oxidoreductase; Xanthoxin + NAD+ <=> Abscisic aldehyde + NADH + H+ R06955 Xanthoxin <=> Xanthoxic acid R06956 Xanthoxic acid <=> Abscisate R06957 abscisic-aldehyde:oxygen oxidoreductase; Abscisic aldehyde + H2O + Oxygen <=> Abscisate + Hydrogen peroxide R06958 Abscisic aldehyde <=> Abscisic alcohol R06959 Abscisic alcohol <=> Abscisate R06960 carotenoid psi-end group lyase (decyclizing); all-trans-Neurosporene <=> alpha-Zeacarotene R06961 alpha-Zeacarotene <=> delta-Carotene R06962 carotenoid beta-end group lyase (decyclizing); delta-Carotene <=> alpha-Carotene R06963 carotenoid psi-end group lyase (decyclizing); Lycopene <=> delta-Carotene R06964 alpha-Carotene <=> Lutein R06966 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase; 2-Chloro-4-hydroxy-6-amino-1,3,5-triazine + H2O <=> Ammelide + Hydrochloric acid R06967 N-isopropylammelide isopropylaminohydrolase; Ammelide + H2O <=> Cyanuric acid + Ammonia R06968 Melamine + H2O <=> Ammeline + Ammonia R06969 melamine aminohydrolase; Ammeline + H2O <=> Ammelide + Ammonia R06970 Cyromazine + H2O <=> N-Cyclopropylammeline + Ammonia R06971 N-Cyclopropylammeline + H2O <=> N-Cyclopropylammelide + Ammonia R06972 N-Cyclopropylammelide + H2O <=> Cyanuric acid + Cyclopropylamine R06973 3-oxopropanoate carboxy-lyase; 3-Oxopropanoate <=> Acetaldehyde + CO2 R06974 formate:N1-(5-phospho-beta-D-ribosyl)glycinamide ligase (ADP-forming); Formate + ATP + 5'-Phosphoribosylglycinamide <=> ADP + Orthophosphate + 5'-Phosphoribosyl-N-formylglycinamide R06975 formate:5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ligase (ADP-forming); 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase; Formate + ATP + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide R06976 ATP + Lombricine <=> ADP + N-Phospholombricine R06977 L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase; L-Glutamate + L-Aspartate 4-semialdehyde <=> 2-Oxoglutarate + L-2,4-Diaminobutanoate R06978 acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase; L-2,4-Diaminobutanoate + Acetyl-CoA <=> N(gamma)-Acetyldiaminobutyrate + CoA R06979 ectoine hydro-lyase; N(gamma)-Acetyldiaminobutyrate <=> H2O + Ectoine R06980 sulfoacetaldehyde:NAD+ oxidoreductase; Sulfoacetaldehyde + NAD+ + H2O <=> Sulfoacetate + NADH + H+ R06981 isethionate:ferricytochrome-c oxidoreductase; 2-Hydroxyethanesulfonate + 2 Ferricytochrome c <=> Sulfoacetaldehyde + 2 Ferrocytochrome c + 2 H+ R06982 S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming); S-(hydroxymethyl)glutathione synthase; Glutathione + Formaldehyde <=> S-(Hydroxymethyl)glutathione R06983 S-(hydroxymethyl)glutathione dehydrogenase; S-(Hydroxymethyl)glutathione + NAD+ <=> S-Formylglutathione + NADH + H+ R06985 trans-Hex-2-enoyl-CoA reductase; trans-Hex-2-enoyl-CoA + NADPH + H+ <=> Hexanoyl-CoA + NADP+ R06986 GDP-mannose:N-linked oligosaccharide alpha-1,6-D-mannosyltransferase; GDP-D-mannose + G00011 <=> GDP + G10694 R06987 propanoyl-CoA:formate C-propanoyltransferase; 2-Oxobutanoate + CoA <=> Propanoyl-CoA + Formate R06988 3-(hydroxyamino)phenol hydroxymutase; 3-Hydroxyaminophenol <=> Aminohydroquinone R06989 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing); cis,cis-Muconate <=> (S)-5-Oxo-2,5-dihydrofuran-2-acetate R06990 (S)-5-oxo-2,5-dihydrofuran-2-acetate delta3-delat2-isomerase; (S)-5-Oxo-2,5-dihydrofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate R06991 34a-Deoxy-rifamycin W <=> Rifamycin W R06992 Rifamycin W <=> Rifamycin W-hemiacetal R06993 Rifamycin W <=> Rifamycin Z R06994 Rifamycin W-hemiacetal <=> Demethyl-desacetyl-rifamycin S R06995 Rifamycin Z <=> Demethyl-desacetyl-rifamycin S R06996 Demethyl-desacetyl-rifamycin S <=> 27-O-Demethyl-25-O-desacetylrifamycin SV R06997 Acetyl-CoA + 27-O-Demethyl-25-O-desacetylrifamycin SV <=> CoA + 27-O-Demethylrifamycin SV R06998 S-adenosyl-L-methionine:27-O-demethylrifamycin-SV 27-O-methyltransferase; S-Adenosyl-L-methionine + 27-O-Demethylrifamycin SV <=> S-Adenosyl-L-homocysteine + Rifamycin R06999 Rifamycin <=> Rifamycin S R07000 naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Naphthalene + NADPH + Oxygen + H+ <=> (1R,2S)-Naphthalene 1,2-oxide + NADP+ + H2O R07001 naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O R07002 (1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming); (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene R07003 (1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming); (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene R07004 (1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming); (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene R07005 (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene <=> (1R)-Hydroxy-(2R)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene R07006 (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R)-N-Acetyl-L-cysteinyl-(2R)-hydroxy-1,2-dihydronaphthalene R07007 (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene <=> (1R,2R)-3-[(1,2-Dihydro-2-hydroxy-1-naphthalenyl)thio]-2-oxopropanoic acid R07008 (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene <=> (1S)-Hydroxy-(2S)-N-acetyl-L-cysteinyl-1,2-dihydronaphthalene R07009 (1R,2S)-Naphthalene 1,2-oxide <=> 1-Naphthol R07010 (1S,2R)-Naphthalene 1,2-oxide <=> 1-Naphthol R07011 (1R,2S)-Naphthalene 1,2-oxide <=> 2-Naphthol R07012 (1S,2R)-Naphthalene 1,2-oxide <=> 2-Naphthol R07013 (1R,2S)-naphthalene 1,2-oxide hydrolase; (1R,2S)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol R07014 (1S,2R)-naphthalene 1,2-oxide hydrolase; (1S,2R)-Naphthalene 1,2-oxide + H2O <=> 1,2-Dihydronaphthalene-1,2-diol R07015 1,2-dihydronaphthalene-1,2-diol dehydrogenase; 1,2-Dihydronaphthalene-1,2-diol + NADP+ <=> Naphthalene-1,2-diol + NADPH + H+ R07016 1,2-dihydronaphthalene-1,2-diol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1,2-Dihydronaphthalene-1,2-diol + NADPH + Oxygen + H+ <=> 1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydronaphthalene + NADP+ + H2O R07017 Naphthalene-1,2-diol <=> 1,2-Naphthoquinone R07018 1-Naphthol <=> 1,4-Dihydroxynaphthalene R07019 1,4-Dihydroxynaphthalene <=> 1,4-Naphthoquinone R07020 beta-naphthol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 2-Naphthol + NADPH + Oxygen + H+ <=> Naphthalene-1,2-diol + NADP+ + H2O R07021 1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-7,8-oxide + NADP+ + H2O R07022 1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1-Nitronaphthalene + NADPH + Oxygen + H+ <=> 1-Nitronaphthalene-5,6-oxide + NADP+ + H2O R07023 1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming); 1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene R07024 1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming); 1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene R07025 1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming); 1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene R07026 1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming); 1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene R07027 1-nitronaphthalene-5,6-oxide hydrolase; 1-Nitronaphthalene-5,6-oxide + H2O <=> 1-Nitro-5,6-dihydroxy-dihydronaphthalene R07028 1-Nitronaphthalene <=> 1-Nitrosonaphthalene R07029 1-Nitrosonaphthalene <=> N-Hydroxy-1-aminonaphthalene R07030 N-Hydroxy-1-aminonaphthalene <=> 1-Naphthylamine R07031 5,6-Epoxytetraene + H2O <=> Lipoxin A4 R07032 5,6-Epoxytetraene + H2O <=> Lipoxin B4 R07034 glutathione: 5-HPETE oxidoreductase; 2 Glutathione + 5(S)-HPETE <=> Glutathione disulfide + 5(S)-HETE + H2O R07035 glutathione: 15-HPETE oxidoreductase; 2 Glutathione + 15(S)-HPETE <=> Glutathione disulfide + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + H2O R07036 hepoxilin A3 hydrolase; Hepoxilin A3 + H2O <=> Trioxilin A3 R07037 hepoxilin B3 hydrolase; Hepoxilin B3 + H2O <=> Trioxilin B3 R07038 arachidonate: oxygen 12-oxidoreductase; Arachidonate + Oxygen <=> 12(R)-HPETE R07039 12(S)-HPETE hydroxymutase; 12(S)-HPETE <=> Hepoxilin A3 R07040 12(S)-HPETE hydroxymutase; 12(S)-HPETE <=> Hepoxilin B3 R07041 arachidonic acid:oxygen 1-oxidoreductase; Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O R07042 15(S)-HPETE <=> 15H-11,12-EETA R07043 15(S)-HPETE <=> 11H-14,15-EETA R07044 15H-11,12-EETA + H2O <=> 11,12,15-THETA R07045 11H-14,15-EETA + H2O <=> 11,14,15-THETA R07046 Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19(S)-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O R07047 arachidonate: oxygen 11-oxidoreductase; Arachidonate + Oxygen <=> 11(R)-HPETE R07048 Arachidonate + Oxygen + NADPH + H+ <=> 14,15-EET + NADP+ + H2O R07049 arachidonate:oxygen 9-oxidoreductase; Arachidonate + Oxygen <=> 9(S)-HPETE R07050 Arachidonate + Oxygen + NADPH + H+ <=> 11,12-EET + NADP+ + H2O R07051 Arachidonate + Oxygen + NADPH + H+ <=> 8,9-EET + NADP+ + H2O R07052 Arachidonate + Oxygen + NADPH + H+ <=> 5,6-EET + NADP+ + H2O R07053 arachidonate:oxygen 8-oxidoreductase; Arachidonate + Oxygen <=> 8(S)-HPETE R07054 Arachidonate + Oxygen + NADPH + H+ <=> 16(R)-HETE + NADP+ + H2O R07055 Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O R07056 Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O R07057 linoleate:oxygen 9-oxidoreductase; Linoleate + Oxygen <=> 9(S)-HPODE R07058 13-HODE:NAD+ oxidoreductase; 13(S)-HODE + NAD+ <=> 13-OxoODE + NADH + H+ R07059 GDP-4-dehydro-6-deoxy-D-mannose <=> GDP-4-keto-6-L-deoxygalactose R07060 GDP-4-keto-6-L-deoxygalactose + NADPH + H+ <=> GDP-L-fucose + NADP+ R07061 linoleate:oxygen (8R)-oxidoreductase; Linoleate + Oxygen <=> 8(R)-HPODE R07062 (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate hydroxymutase [(7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate-forming]; 8(R)-HPODE <=> (7S,8S)-DiHODE R07063 linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase; Linoleate + Reduced acceptor + Oxygen <=> (6Z,9Z,12Z)-Octadecatrienoic acid + Acceptor + 2 H2O R07064 phosphatidylcholine 2-acylhydrolase; Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate R07066 bromobenzene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-3,4-oxide + NADP+ + H2O R07067 Delta-12-Prostaglandin J2 <=> 15-Deoxy-Delta12,14-PGJ2 + H2O R07068 bromobenzene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Bromobenzene + NADPH + Oxygen + H+ <=> Bromobenzene-2,3-oxide + NADP+ + H2O R07069 3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming); Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene R07070 2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming); Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene R07071 bromobenzene-3,4-oxide hydrolase; Bromobenzene-3,4-oxide + H2O <=> Bromobenzene-3,4-dihydrodiol R07072 bromobenzene-2,3-oxide hydrolase; Bromobenzene-2,3-oxide + H2O <=> Bromobenzene-2,3-dihydrodiol R07073 Bromobenzene-3,4-oxide <=> 4-Bromophenol R07074 Bromobenzene-2,3-oxide <=> 2-Bromophenol R07075 4-bromophenol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 4-Bromophenol + NADPH + Oxygen + H+ <=> 4-Bromophenol-2,3-epoxide + NADP+ + H2O R07076 4-Bromophenol-2,3-epoxide <=> 4-Bromocatechol R07077 4-Bromocatechol <=> 4-Bromo-3,5-cyclohexadiene-1,2-dione R07078 Bromobenzene-3,4-dihydrodiol <=> 4-Bromocatechol R07079 benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O R07080 benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-oxide + NADP+ + H2O R07081 benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-4,5-oxide + NADP+ + H2O R07082 benzo[a]pyrene-7,8-oxide hydrolase; Benzo[a]pyrene-7,8-oxide + H2O <=> Benzo[a]pyrene-7,8-dihydrodiol R07083 4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming); Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene R07084 7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase; Benzo[a]pyrene-7,8-dihydrodiol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O R07085 benzo[a]pyrene-7,8-diol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Benzo[a]pyrene-7,8-dihydrodiol + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O R07086 Benzo[a]pyrene-9,10-oxide <=> 9-Hydroxybenzo[a]pyrene R07087 9-hydroxybenzo[a]pyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 9-Hydroxybenzo[a]pyrene + NADPH + Oxygen + H+ <=> 9-Hydroxybenzo[a]pyrene-4,5-oxide + NADP+ + H2O R07088 1,1-dichloroethylene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 2,2-Dichloroacetaldehyde + NADP+ + H2O R07089 1,1-dichloroethylene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> 1,1-Dichloroethylene epoxide + NADP+ + H2O R07090 1,1-dichloroethylene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1,1-Dichloroethylene + NADPH + Oxygen + H+ <=> Chloroacetyl chloride + NADP+ + H2O R07091 S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming); 2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione R07092 1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]; 1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid R07093 chloroacetyl-chloride:glutathione S-chloroacetyltransferase; Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid R07094 2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase; 2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid R07095 2,2-Dichloroacetaldehyde + H2O <=> 2,2-Dichloro-1,1-ethanediol R07096 Chloroacetyl chloride + H2O <=> Chloroacetic acid R07097 2-(S-Glutathionyl)acetyl chloride + H2O <=> 2-S-Glutathionyl acetate R07098 trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O R07099 trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O R07100 trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase; Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid R07101 Chloral + H2O <=> Chloral hydrate R07102 TCE epoxide <=> Dichloroacetyl chloride R07103 Dichloroacetyl chloride <=> Dichloroacetate R07104 chloral:NAD(P)+ oxidoreductase; Chloral hydrate + NAD+ <=> Trichloroacetate + NADH + H+ R07105 trichloroethanol:NAD+ oxidoreductase; Chloral hydrate + NADH + H+ <=> Trichloroethanol + NAD+ + H2O R07106 UDP-glucuronate beta-D-glucuronosyltransferase; Trichloroethanol + UDP-glucuronate <=> Trichloroethanol glucuronide + UDP R07107 trichloroethanol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); Trichloroethanol + 2 NADPH + 2 Oxygen + 2 H+ <=> Trichloroacetate + 2 NADP+ + 3 H2O R07108 14,15-EET hydrolase; 14,15-EET + H2O <=> 14,15-DHET R07109 11,12-EET hydrolase; 11,12-EET + H2O <=> 11,12-DHET R07110 8,9-EET hydrolase; 8,9-EET + H2O <=> 8,9-DHET R07111 5,6-EET hydrolase; 5,6-EET + H2O <=> 5,6-DHET R07112 1,2-dibromoethane,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing); 1,2-Dibromoethane + NADPH + Oxygen + H+ <=> 2-Bromoacetaldehyde + NADP+ + H2O + Hydrobromic acid R07113 1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming); 1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid R07114 S-(Formylmethyl)glutathione <=> Thiodiacetic acid R07115 S-(Formylmethyl)glutathione <=> Thiodiacetic acid sulfoxide R07116 2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase; 2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid R07117 Glutathione episulfonium ion + H2O <=> S-(2-Hydroxyethyl)glutathione R07118 S-(2-Hydroxyethyl)glutathione <=> S-(2-Hydroxyethyl)-N-acetyl-L-cysteine R07119 Glutathione episulfonium ion <=> S-[2-(N7-Guanyl)ethyl]-N-acetyl-L-cysteine R07120 S-(Formylmethyl)glutathione <=> S-(2-Hydroxyethyl)glutathione R07121 12(13)-EpOME hydrolase; 12(13)-EpOME + H2O <=> 12,13-DHOME R07122 9(10)-EpOME hydrolase; 9(10)-EpOME + H2O <=> 9,10-DHOME R07123 Trichloroacetate <=> Dichloroacetate R07124 2-(S-Glutathionyl)acetyl glutathione + H2O <=> 2-S-Glutathionyl acetate + Glutathione R07125 3-dehydro-L-gulonate-6-phosphate carboxy-lyase; 3-Dehydro-L-gulonate 6-phosphate + H+ <=> L-Xylulose 5-phosphate + CO2 R07127 ATP:3-dehydro-L-gulonate 6-phosphotransferase; 3-Dehydro-L-gulonate + ATP <=> 3-Dehydro-L-gulonate 6-phosphate + ADP R07128 oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating); Oplophorus luciferin + Oxygen <=> Oxidized Oplophorus luciferin + hn + CO2 R07129 Dolichyl phosphate D-mannose + G00149 <=> Dolichyl phosphate + G00140 R07131 G02047 + 2 UDP-N-acetyl-D-glucosamine <=> G06302 + 2 UDP R07133 D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase; Sorbitol 6-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+ R07134 D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming); D-Arabitol + NAD+ <=> D-Ribulose + NADH + H+ R07135 mannitol:NAD+ 1-oxidoreductase; Mannitol + NAD+ <=> D-Mannose + NADH + H+ R07136 (2R)-3-sulfolactate:NAD+ oxidoreductase; (2R)-3-Sulfolactate + NAD+ <=> 3-Sulfopyruvate + NADH + H+ R07137 (2R)-3-sulfolactate:NADP+ oxidoreductase; (2R)-3-Sulfolactate + NADP+ <=> 3-Sulfopyruvate + NADPH + H+ R07138 3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase; Isopregnanolone + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+ R07140 S-(hydroxymethyl)glutathione:NADP+ oxidoreductase; S-(Hydroxymethyl)glutathione + NADP+ <=> S-Formylglutathione + NADPH + H+ R07141 2'-deoxymugineic acid:NAD+ 3''-oxidoreductase; 2'-Deoxymugineic acid + NAD+ <=> 3''-Deamino-3''-oxonicotianamine + NADH + H+ R07142 2'-deoxymugineic acid:NADP+ 3''-oxidoreductase; 2'-Deoxymugineic acid + NADP+ <=> 3''-Deamino-3''-oxonicotianamine + NADPH + H+ R07143 D-arabinitol:NADP+ oxidoreductase; D-Arabitol + NADP+ <=> D-Xylulose + NADPH + H+ R07144 D-arabinitol:NADP+ oxidoreductase; D-Arabitol + NADP+ <=> D-Ribulose + NADPH + H+ R07145 L-iditol:NAD+ 2-oxidoreductase; L-Iditol + NAD+ <=> L-Sorbose + NADH + H+ R07146 cis-4-hydroxy-L-proline:NAD+ oxidoreductase (4-oxo-L-proline forming); cis-4-Hydroxy-L-proline + NAD+ <=> 4-Oxoproline + NADH + H+ R07147 D-glucose:NADP+ 1-oxidoreductase; D-Glucose + NADP+ <=> D-Glucono-1,5-lactone + NADPH + H+ R07148 D-threo-aldose:NAD+ 1-oxidoreductase; D-threo-Aldose + NAD+ <=> D-threo-Aldono-1,5-lactone + NADH + H+ R07149 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NADP+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4alpha-Methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH + H+ R07150 dTDP-D-galactose:NADP+ 6-oxidoreductase; dTDP-galactose + 2 NADP+ + H2O <=> dTDP-D-galacturonate + 2 NADPH + 2 H+ R07151 L-2-hydroxyphytanate:oxygen 2-oxidoreductase; L-2-Hydroxyphytanate + Oxygen <=> 2-Oxophytanate + Hydrogen peroxide R07152 xylitol:oxygen oxidoreductase; Xylitol + Oxygen <=> D-Xylose + Hydrogen peroxide R07153 2-dehydro-D-gluconate:acceptor 2-oxidoreductase; 2-Keto-D-gluconic acid + Acceptor <=> 2,5-Didehydro-D-gluconate + Reduced acceptor R07154 pyridoxine:(acceptor) 5-oxidoreductase; Pyridoxine + Acceptor <=> Isopyridoxal + Reduced acceptor R07155 (2R)-hydroxy-carboxylate:acceptor oxidoreductase; (R)-2-Hydroxyacid + Acceptor <=> 2-Oxo acid + Reduced acceptor R07156 fluoroacetaldehyde:NAD+ oxidoreductase; Fluoroacetaldehyde + NAD+ + H2O <=> Fluoroacetate + NADH + H+ R07157 carbon-monoxide,water:ferredoxin oxidoreductase; CO + H2O + 2 Oxidized ferredoxin <=> CO2 + 2 Reduced ferredoxin + 2 H+ R07158 aldehyde:ferredoxin oxidoreductase; Aldehyde + H2O + 2 Oxidized ferredoxin <=> Carboxylate + 2 Reduced ferredoxin + 2 H+ R07159 D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; D-Glyceraldehyde 3-phosphate + H2O + 2 Oxidized ferredoxin <=> 3-Phospho-D-glycerate + 2 H+ + 2 Reduced ferredoxin R07160 3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating;CoA-2-methylpropanoylating); 3-Methyl-2-oxobutanoic acid + CoA + 2 Oxidized ferredoxin <=> 2-Methylpropanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+ R07161 3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating,CoA-indole-acetylating); Indolepyruvate + CoA + Oxidized ferredoxin <=> S-2-(Indol-3-yl)acetyl-CoA + CO2 + Reduced ferredoxin R07162 acyl-CoA:NADP+ trans-2-oxidoreductase; Acyl-CoA + NADP+ <=> trans-2,3-Dehydroacyl-CoA + NADPH + H+ R07163 all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas; all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor R07164 L-aspartate:NAD+ oxidoreductase (deaminating); L-Aspartate + H2O + NAD+ <=> Oxaloacetate + Ammonia + NADH + H+ R07165 L-aspartate:NADP+ oxidoreductase (deaminating); L-Aspartate + H2O + NADP+ <=> Oxaloacetate + Ammonia + NADPH + H+ R07166 D-amino-acid:(acceptor) oxidoreductase (deaminating); D-Amino acid + H2O + Acceptor <=> 2-Oxo acid + Ammonia + Reduced acceptor R07167 taurine:(acceptor) oxidoreductase (deaminating); Taurine + H2O + Acceptor <=> Sulfoacetaldehyde + Ammonia + Reduced acceptor R07168 5-methyltetrahydrofolate:NAD+ oxidoreductase; 5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+ R07169 (R)-tetrahydroberberine:NADP+ oxidoreductase; (R)-Canadine + 2 NADP+ <=> Berberine + 2 NADPH + 2 H+ R07170 (R)-6-hydroxynicotine:oxygen oxidoreductase; (R)-6-Hydroxynicotine + H2O + Oxygen <=> 6-Hydroxypseudooxynicotine + Hydrogen peroxide R07171 NADH:oxygen oxidoreductase; NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide R07172 NADPH:oxygen oxidoreductase; NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide R07174 hydrazine:ferricytochrome c oxidoreductase; Hydrazine + 4 Ferricytochrome c <=> Nitrogen + 4 Ferrocytochrome c R07175 CoA:NADP+ oxidoreductase; 2 CoA + NADP+ <=> CoA-disulfide + NADPH + H+ R07176 AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming); AMP + Sulfite + Thioredoxin disulfide <=> Adenylyl sulfate + Thioredoxin R07177 thiosulfate:6-decylubiquinone oxidoreductase; 2 Thiosulfate + Decylubiquinone <=> Tetrathionate + Decylubiquinol R07178 violaxanthin:ascorbate oxidoreductase; Violaxanthin + Ascorbate <=> Antheraxanthin + Dehydroascorbate + H2O R07179 antheraxanthin:ascorbate oxidoreductase; Antheraxanthin + Ascorbate <=> Zeaxanthin + Dehydroascorbate + H2O R07181 hydrogen:NADP+ oxidoreductase; Hydrogen + NADP+ <=> NADPH + H+ R07182 hydrogen:(acceptor) oxidoreductase; Hydrogen + Acceptor <=> Reduced acceptor R07183 acetylacetone:oxygen oxidoreductase; Pentane-2,4-dione + Oxygen <=> Acetate + Methylglyoxal R07184 (gibberellin-44),2-oxoglutarate:oxygen oxidoreductase; Gibberellin A44 + 2-Oxoglutarate + Oxygen <=> Gibberellin A19 + Succinate + CO2 R07185 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase(2-hydroxylating); 2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> Mugineic acid + Succinate + CO2 R07186 mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Mugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2 R07187 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); 2'-Deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxy-2'-deoxymugineic acid + Succinate + CO2 R07188 benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); Benzoate + NADH + H+ + Oxygen <=> 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ R07190 N,N-Dihydroxy-L-tyrosine <=> (E)-4-Hydroxyphenylacetaldehyde oxime + CO2 + H2O R07191 tetrachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating); 2,3,5,6-Tetrachlorophenol + NADPH + H+ + Oxygen <=> Tetrachlorohydroquinone + NADP+ + H2O R07192 ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating,ester-producing); Ketosteroid + NADPH + H+ + Oxygen <=> Steroid ester + NADP+ + H2O R07193 ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing); Ketosteroid + NADPH + H+ + Oxygen <=> Steroid lactone + NADP+ + H2O R07194 alkene,NADH:oxygen oxidoreductase; Propylene + NADH + H+ + Oxygen <=> 1,2-Epoxypropane + NAD+ + H2O R07195 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing); Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Glyceollin II + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07196 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing); Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin III + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07197 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing); 4-Glyceollidin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-Glyceollin I + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07198 liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (licodione-forming); Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Licodione + [Oxidized NADPH---hemoprotein reductase] + H2O R07201 phenylacetone,NADPH:oxygen oxidoreductase; Phenylacetone + NADPH + H+ + Oxygen <=> Benzyl acetate + NADP+ + H2O R07202 abscisate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8'-hydroxylating); Abscisate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8'-Hydroxyabscisate + [Oxidized NADPH---hemoprotein reductase] + H2O R07203 lithocholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6beta-hydroxylating); Lithocholic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Murideoxycholate + [Oxidized NADPH---hemoprotein reductase] + H2O R07204 5beta-cholestane-3alpha,7alpha-diol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating); 3alpha,7alpha-Dihydroxy-5beta-cholestane + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + [Oxidized NADPH---hemoprotein reductase] + H2O R07205 taurochenodeoxycholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); Taurochenodeoxycholate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Taurohyocholate + [Oxidized NADPH---hemoprotein reductase] + H2O R07206 lithocholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); Lithocholic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Hyodeoxycholate + [Oxidized NADPH---hemoprotein reductase] + H2O R07207 cholesterol,NADPH-hemoprotein reductase:oxygen oxidoreductase (24-hydroxylating); Cholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cerebrosterol + [Oxidized NADPH---hemoprotein reductase] + H2O R07208 (24S)-cholest-5-ene-3beta,24-diol,NADPH-hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating); Cerebrosterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (24S)-Cholest-5-ene-3beta,7alpha,24-triol + [Oxidized NADPH---hemoprotein reductase] + H2O R07209 cholest-5-ene-3beta,25-diol,[NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating); 25-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cholest-5-ene-3beta,7alpha,25-triol + [Oxidized NADPH---hemoprotein reductase] + H2O R07210 alkanesulfonate,reduced-FMN:oxygen oxidoreductase; Alkanesulfonate + Reduced FMN + Oxygen <=> Aldehyde + FMN + Sulfite + H2O R07211 L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase(4-hydroxylating); L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> L-Tyrosine + 4a-Hydroxytetrahydrobiopterin R07212 L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase(3-hydroxylating); L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin R07213 L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating); L-Tryptophan + Tetrahydrobiopterin + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin R07214 1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming); 1-Aminocyclopropane-1-carboxylate + Ascorbate + Oxygen <=> Ethylene + Cyanide ion + Dehydroascorbate + CO2 + 2 H2O R07215 lathosterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating; Lathosterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 7-Dehydrocholesterol + 2 Ferricytochrome b5 + 2 H2O R07216 n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]; Tetradecanoyl-CoA + NADPH + H+ + Oxygen <=> (E)-11-Tetradecenoyl-CoA + NADP+ + 2 H2O R07217 n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]; Tetradecanoyl-CoA + NADPH + H+ + Oxygen <=> (Z)-11-Tetradecenoyl-CoA + NADP+ + 2 H2O R07218 cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating); Cholesterol + Reduced acceptor + Oxygen <=> 25-Hydroxycholesterol + Acceptor + H2O R07220 deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating); Deoxycholic acid + FAD + H2O <=> Cholic acid + FADH2 R07221 6-hydroxynicotinate:O2 oxidoreductase; 6-Hydroxynicotinate + H2O + Oxygen <=> 2,6-Dihydroxynicotinate + Hydrogen peroxide R07222 phenylacetyl-CoA:quinone oxidoreductase; Phenylacetyl-CoA + H2O + 2 Quinone <=> Phenylglyoxylyl-CoA + 2 Hydroquinone R07224 2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase; Naringenin chalcone + Oxygen <=> Aureusidin + H2O R07225 2',3,4,4',6'-pentahydroxychalcone:oxygen oxidoreductase; 2 Eriodictyol chalcone + Oxygen <=> 2 Aureusidin + 2 H2O R07226 acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming); Acetyl phosphate + Ammonia + Thioredoxin disulfide + H2O <=> Glycine + Orthophosphate + Thioredoxin R07227 acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming); Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O <=> Sarcosine + Orthophosphate + Thioredoxin R07228 acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming); Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O <=> Betaine + Orthophosphate + Thioredoxin R07229 ferricytochrome c:selenite oxidoreductase; Selenite + H2O + Ferricytochrome c <=> Selenate + Ferrocytochrome c R07230 acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating); 3,3',5'-Triiodo-L-thyronine + Iodide + Acceptor + H+ <=> Thyroxine + Reduced acceptor R07232 S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase; S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N6-methyladenine R07233 S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase; S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine R07234 S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase; S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N2-methylguanine R07236 S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase; S-Adenosyl-L-methionine + gamma-Tocopherol <=> S-Adenosyl-L-homocysteine + alpha-Tocopherol R07237 S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase; S-Adenosyl-L-methionine + Uroporphyrinogen III <=> S-Adenosyl-L-homocysteine + Precorrin 1 R07238 S-adenosyl-L-methionine:precorrin-1 C-methyltransferase; S-Adenosyl-L-methionine + Precorrin 1 <=> S-Adenosyl-L-homocysteine + Precorrin 2 R07239 S-Adenosyl-L-methionine + [Cytochrome c]-arginine <=> S-Adenosyl-L-homocysteine + [Cytochrome c]-N(omega)-methylarginine R07240 S-adenosyl-L-methionine:isoeugenol O-methyltransferase; S-Adenosyl-L-methionine + Isoeugenol <=> S-Adenosyl-L-homocysteine + Methylisoeugenol R07241 S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase; S-Adenosyl-L-methionine + Palmatine + 2 NADPH <=> S-Adenosyl-L-homocysteine + Corydaline + 2 NADP+ R07242 S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase; S-Adenosyl-L-methionine + Isoliquiritigenin <=> S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin R07243 S-adenosyl-L-methionine:sarcosine N-methyltransferase; S-Adenosyl-L-methionine + Sarcosine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylglycine R07244 S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase; S-Adenosyl-L-methionine + N,N-Dimethylglycine <=> S-Adenosyl-L-homocysteine + Betaine R07245 carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase; Carbamoyl phosphate + N-Acetylornithine <=> Orthophosphate + N-Acetyl-L-citrulline R07247 fluoroacetaldehyde:L-threonine aldehydetransferase; L-Threonine + Fluoroacetaldehyde <=> Acetaldehyde + 4-Fluoro-L-threonine R07248 alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase; 2 alpha,alpha'-Trehalose 6-mycolate <=> alpha,alpha-Trehalose + alpha,alpha'-Trehalose 6,6'-bismycolate R07249 acetyl-CoA:polysialic-acid O-acetyltransferase; Acetyl-CoA + alpha-2,8-Linked polymer of sialic acid <=> CoA + Polysialic acid acetylated at O-9 R07250 malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing); 3 Malonyl-CoA + N-Methylanthraniloyl-CoA <=> 4 CoA + 1,3-Dihydroxy-N-methylacridone + 3 CO2 + H2O R07251 acyl-CoA:malonyl-CoA C-acyltransferase (dihydromonacolin L-[acp]-forming); 9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein <=> Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O R07252 acetyl-CoA:taxan-10beta-ol O-acetyltransferase; Acetyl-CoA + 10-Desacetyltaxuyunnanin C <=> CoA + Taxuyunnanin C R07253 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing); Acetyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O R07255 malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase; Malonyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) R07256 NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase; NDP-glucose + D-Fructose <=> NDP + Sucrose R07257 GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase; GDP-mannose + di-trans,poly-cis-Undecaprenyl phosphate <=> GDP + D-Mannosyl-1-phosphoundecaprenol R07258 UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 6-(alpha-D-Mannosyl)-beta-D-mannosyl-R <=> UDP + 6-(2-[N-Acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R R07259 UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + beta-D-Mannosyl-R <=> UDP + 4-(N-Acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R R07260 UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase; UDP-glucose + cis-Zeatin <=> UDP + O-beta-D-Glucopyranosyl-cis-zeatin R07261 NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase; NDP-glucose + Amylose <=> NDP + Amylose R07262 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; 1,4-Dihydroxy-2-naphthoyl-CoA + H2O <=> 1,4-Dihydroxy-2-naphthoate + CoA R07263 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA dehydratase (cyclizing); 2-Succinylbenzoyl-CoA <=> 1,4-Dihydroxy-2-naphthoyl-CoA + H2O R07264 2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase; 2-alpha-D-Glucosyl-D-glucose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R07265 alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase; alpha,alpha-Trehalose + Orthophosphate <=> alpha-D-Glucose + D-Glucose 1-phosphate R07266 UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase; UDP-glucose + Anthocyanin <=> UDP + Anthocyanin 3'-O-beta-D-glucoside R07267 (E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase; all-trans-Octaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + all-trans-Nonaprenyl diphosphate R07268 ATP:cobinamide Cobeta-adenosyltransferase; ATP + Cobinamide <=> Triphosphate + Adenosyl cobinamide R07269 di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase; di-trans,poly-cis-Decaprenyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + di-trans,poly-cis-Undecaprenyl diphosphate R07270 prephytoene diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase; Prephytoene diphosphate <=> all-trans-Phytoene + Diphosphate R07271 dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase; Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + Glyceocarpin R07272 dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase; Dimethylallyl diphosphate + 3,6,9-Trihydroxypterocarpan <=> Diphosphate + 4-Glyceollidin R07273 solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase; all-trans-Nonaprenyl diphosphate + 4-Hydroxybenzoate <=> Diphosphate + 3-Nonaprenyl-4-hydroxybenzoate R07274 O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; O-Phospho-L-serine + Hydrogen sulfide <=> L-Cysteine + Orthophosphate R07275 diamine:2-oxoglutarate aminotransferase; alpha,omega-Diamine + 2-Oxoglutarate <=> omega-Aminoaldehyde + L-Glutamate R07276 L-arogenate:2-oxoglutarate aminotransferase; L-Arogenate + 2-Oxoglutarate <=> Prephenate + L-Glutamate R07277 nicotianamine:2-oxoglutarate aminotransferase; nicotianamine transaminase; Nicotianamine + 2-Oxoglutarate <=> 3''-Deamino-3''-oxonicotianamine + L-Glutamate R07278 dGTP:depurinated-DNA purine transferase; dGTP + Depurinated DNA <=> Deoxyribose triphosphate + DNA containing guanine R07279 ATP:1D-myo-inositol 3-phosphotransferase; ATP:1L-myo-inositol 1-phosphotransferase; ATP + myo-Inositol <=> ADP + 1D-myo-Inositol 3-phosphate R07280 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphohydrolase; 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + H2O <=> 5-Amino-6-(1-D-ribitylamino)uracil + Orthophosphate R07281 D-ribulose 5-phosphate formate-lyase (L-3,4-dihydroxybutan-2-one 4-phosphate-forming); D-Ribulose 5-phosphate <=> L-3,4-Dihydroxybutan-2-one 4-phosphate + Formate R07282 polyribonucleotide:phosphate nucleotidyltransferase; RNA + Orthophosphate <=> RNA + NDP R07285 tRNA:phosphate nucleotidyltransferase; tRNA + Orthophosphate <=> tRNA + NDP R07287 3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase; 3'-Phosphoadenylyl sulfate + Glycolithocholate <=> Adenosine 3',5'-bisphosphate + Sulfoglycolithocholate R07288 3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 6'-sulfate R07289 3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase; 3'-Phosphoadenylyl sulfate + Glycochenodeoxycholate <=> Adenosine 3',5'-bisphosphate + Glycochenodeoxycholate 7-sulfate R07290 formyl-CoA:oxalate CoA-transferase; Formyl-CoA + Oxalate <=> Formate + Oxalyl-CoA R07291 2-lysophosphatidylcholine acylhydrolase; 1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Carboxylate R07292 4-hydroxy-3-methoxycinnamoyl-sugar hydrolase; Feruloyl-polysaccharide + H2O <=> Ferulate + Polysaccharide R07293 monoacylglycerol acylhydrolase; 1-Acylglycerol + H2O <=> Glycerol + Carboxylate R07294 phenylglyoxylyl-CoA hydrolase; Phenylglyoxylyl-CoA + H2O <=> alpha-Oxo-benzeneacetic acid + CoA R07295 deoxycholoyl-CoA:cholate CoA-transferase; Deoxycholoyl-CoA + Cholic acid <=> Deoxycholic acid + Choloyl-CoA R07296 choloyl-CoA hydrolase; Choloyl-CoA + H2O <=> Cholic acid + CoA R07297 5'-ribonucleotide phosphohydrolase; 5'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate R07298 sn-glycerol-1-phosphate phosphohydrolase; sn-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate R07299 1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate R07300 N8-acetylspermidine amidohydrolase; N8-Acetylspermidine + H2O <=> Acetate + Spermidine R07301 (S)-N-acetylphenylethylamine:H2O hydrolase; N-(2-Phenylethyl)-acetamide + H2O <=> Phenethylamine + Acetate R07302 adenosylcobyric acid:(R)-1-aminopropan-2-ol ligase (ADP-forming); ATP + Adenosyl cobyrinate hexaamide + (R)-1-Aminopropan-2-ol <=> ADP + Orthophosphate + Adenosyl cobinamide R07303 N-benzylformamide amidohydrolase; N-Benzylformamide + H2O <=> Formate + Benzylamine R07306 GTP 8,9-hydrolase (phosphate-forming); GTP + 3 H2O <=> 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 Orthophosphate R07307 dCTP aminohydrolase (dUMP-forming); dCTP + 2 H2O <=> dUMP + Diphosphate + Ammonia R07308 (R)-2-haloacid halidohydrolase; (R)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide R07309 (S)-2-haloacid dehalogenase (configuration-retaining); (S)-2-Haloacid + H2O <=> (S)-2-Hydroxyacid + Halide R07310 (R)-2-haloacid dehalogenase (configuration-retaining); (R)-2-Haloacid + H2O <=> (R)-2-Hydroxyacid + Halide R07311 2'-hydroxybiphenyl-2-sulfinate sulfohydrolase; 2'-Hydroxybiphenyl-2-sulfinate + H2O <=> 2-Hydroxybiphenyl + Sulfite R07312 4-hydroxyphenylacetate carboxy-lyase; 4-Hydroxyphenylacetate + H+ <=> 4-Cresol + CO2 R07313 D-dopachrome carboxy-lyase; D-Dopachrome <=> 5,6-Dihydroxyindole + CO2 R07314 (3S)-3-hydroxyacyl-CoA hydro-lyase; (3S)-3-Hydroxyacyl-CoA <=> (3E)-3-Enoyl-CoA + H2O R07316 Carbamate <=> Ammonia + CO2 R07317 2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming); 2,7,4'-Trihydroxyisoflavanone <=> Daidzein + H2O R07318 7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase; 7alpha,12alpha-Dihydroxy-3-oxochol-4-enoate <=> 12alpha-Hydroxy-3-oxochola-4,6-dienoate + H2O R07319 maltose 1-epimerase; alpha-Maltose <=> beta-Maltose R07320 violaxanthin-capsorubin isomerase (ketone-forming); Violaxanthin <=> Capsorubin R07321 antheraxanthin-capsanthin isomerase (ketone-forming); Antheraxanthin <=> Capsanthin R07322 squalene mutase (cyclizing); Squalene <=> Diploptene R07323 squalene mutase (cyclizing); hopan-22-ol hydro-lyase; Squalene + H2O <=> Diplopterol R07324 1D-myo-inositol-3-phosphate lyase (isomerizing); D-Glucose 6-phosphate <=> 1D-myo-Inositol 3-phosphate R07325 acid:[acyl-carrier-protein] ligase (AMP-forming); ATP + Acid + Acyl-carrier protein <=> AMP + Diphosphate + Acyl-[acyl-carrier protein] R07326 alcohol:NAD+ oxidoreductase; Alcohol + NAD+ <=> Aldehyde + NADH + H+ R07328 alcohol:NADP+ oxidoreductase; Alcohol + NADP+ <=> Aldehyde + NADPH + H+ R07329 (2S)-flavan-4-one,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); (2S)-Flavanone + 2-Oxoglutarate + Oxygen <=> (2R,3R)-Dihydroflavonol + Succinate + CO2 R07330 S-adenosyl-L-methionine:catechol O-methyltransferase; S-Adenosyl-L-methionine + Catechol <=> S-Adenosyl-L-homocysteine + Guaiacol R07331 S-adenosyl-L-methionine:4'-hydroxyisoflavone 4'-O-methyltransferase; S-Adenosyl-L-methionine + 4'-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyisoflavone R07332 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; UDP-glucose + Isoflavone <=> UDP + Isoflavone 7-O-beta-D-glucoside R07333 UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase; UDP-glucose + Flavanone <=> UDP + Flavanone 7-O-beta-D-glucoside R07334 UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan + UDP-N-acetyl-alpha-D-glucosamine <=> UDP + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan R07335 UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase; UDP-glucuronate + N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosylproteoglycan R07336 alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-glucuronate + N-Acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan R07337 UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase; UDP-L-rhamnose + Flavanone 7-O-beta-D-glucoside <=> UDP + Flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] R07338 UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase; UDP-glucose + Flavonol <=> UDP + Flavonol 7-O-beta-D-glucoside R07339 UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase; UDP-glucose + Flavonol 3-O-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside R07340 UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase; UDP-glucose + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <=> UDP + Flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside R07341 nucleotide:nucleoside 5'-phosphotransferase; Nucleotide + Deoxynucleoside <=> Nucleoside + Deoxynucleoside 5'-phosphate R07342 aryl-ester hydrolase; Phenyl acetate + H2O <=> Phenol + Acetate R07343 myo-inositol-phosphate phosphohydrolase; myo-Inositol phosphate + H2O <=> myo-Inositol + Orthophosphate R07344 flavanone lyase (decyclizing); Chalcone <=> Flavanone R07345 reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming); (-)-Usnic acid + NADH + H+ <=> (6R)-2-Acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methyl-2,4-cyclohexadien-1-one + NAD+ R07346 D-glucitol:NADP+ oxidoreductase; D-Sorbitol + NADP+ <=> L-Sorbose + NADPH + H+ R07347 pyranose:acceptor oxidoreductase; Pyranose + Acceptor <=> 2-Dehydropyranose + Reduced acceptor R07348 pyranoside:acceptor oxidoreductase; Pyranoside + Acceptor <=> 3-Dehydropyranoside + Reduced acceptor R07349 n-alkanal:NAD+ 2-oxidoreductase; n-Alkanal + NAD+ <=> Alk-2-enal + NADH + H+ R07350 n-alkanal:NADP+ 2-oxidoreductase; n-Alkanal + NADP+ <=> Alk-2-enal + NADPH + H+ R07351 (2R,3R)-flavan-3-ol:NAD+ 3,4-oxidoreductase; (2R,3R)-Flavan-3-ol + 2 NAD+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADH + H+ R07352 (2R,3R)-flavan-3-ol:NADP+ 3,4-oxidoreductase; (2R,3R)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+ R07353 6-(2-amino-2-carboxyethyl)-7,8-dioxo-7,8-dihydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing); 6-(2-Amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 Oxygen <=> PQQ + 2 Hydrogen peroxide + 2 H2O R07354 5,6,7,8-tetrahydropteridine:NAD+ oxidoreductase; Tetrahydropteridine + NAD+ <=> Dihydropteridine + NADH + H+ R07355 5,6,7,8-tetrahydropteridine:NADP+ oxidoreductase; Tetrahydropteridine + NADP+ <=> Dihydropteridine + NADPH + H+ R07356 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing); Glyceocarpin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07357 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing); 4-Glyceollidin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glyceollin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07358 NADH:quinone oxidoreductase; NADH + H+ + Quinone <=> NAD+ + Hydroquinone R07359 NADPH:quinone oxidoreductase; NADPH + H+ + Quinone <=> NADP+ + Hydroquinone R07360 S-prenyl-L-cysteine:oxygen oxidoreductase; Prenyl-L-cysteine + Oxygen + H2O <=> Prenal + L-Cysteine + Hydrogen peroxide R07361 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase; 1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide + Quinone <=> Nicotinamide-beta-riboside + Hydroquinone R07362 D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing); D-Tryptophan + Oxygen <=> N-Formyl-D-kynurenine R07363 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming); 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 3-(Methylthio)propanoate + Formate + CO R07364 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming); 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Formate R07365 sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming); 4 Sulfur + 4 H2O + Oxygen <=> 2 Hydrogen sulfide + 2 Sulfite R07366 leucocyanidin,2-oxoglutarate:oxygen oxidoreductase; Leucocyanidin + 2-Oxoglutarate + Oxygen <=> cis-Dihydroquercetin + Succinate + CO2 + H2O R07367 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Flavanone + 2-Oxoglutarate + Oxygen <=> Flavone + Succinate + CO2 + H2O R07368 dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase; Dihydroflavonol + 2-Oxoglutarate + Oxygen <=> Flavonol + Succinate + CO2 + H2O R07369 flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3'-Hydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O R07370 3'-hydroxyflavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating); 3'-Hydroxyflavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3',5'-Dihydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O R07371 isoflavone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Isoflavone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyisoflavone + [Oxidized NADPH---hemoprotein reductase] + H2O R07372 cholest-5-ene-3beta,26-diol,[NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating); Cholest-5-ene-3beta,26-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha,27-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R07373 senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming); Senecionine + NADPH + H+ + Oxygen <=> Senecionine N-oxide + NADP+ + H2O R07374 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating); (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + Acceptor <=> (24R,25R)-3alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-CoA + Reduced acceptor R07375 S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase; S-Adenosyl-L-methionine + 7-Hydroxyisoflavone <=> S-Adenosyl-L-homocysteine + 7-Methoxyisoflavone R07376 L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase; Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine R07377 Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline R07379 plasmenylethanolamine 2-acylhydrolase; O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate R07380 lysoplasmalogen ethanolamine phosphohydrolase; 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycerol + Ethanolamine phosphate R07381 plasmenylethanolamine ethanolamine phosphohydrolase; O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkenyl-2-acylglycerol + Ethanolamine phosphate R07382 1-(1-Alkenyl)-sn-glycero-3-phosphate + Acyl-CoA <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + CoA R07383 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + H2O <=> 1-Alkenyl-2-acylglycerol + Orthophosphate R07384 O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine R07385 O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + Ethanolamine R07386 O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + Choline <=> Plasmenylcholine + Ethanolamine R07387 plasmanylcholine 2-acylhydrolase; 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate R07388 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase; 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphate + Ethanolamine R07389 1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP R07390 2 Phosphatidylglycerol <=> Cardiolipin + Glycerol R07392 S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase; S-Methyl-5-thio-D-ribulose 1-phosphate <=> 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O R07393 2,3-diketo-5-methylthiopentyl-1-phosphate keto---enol-isomerase; 2,3-Diketo-5-methylthiopentyl-1-phosphate <=> 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate R07394 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate phosphohydrolase; 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate R07395 5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing); 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O <=> 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate R07396 4-Methylthio-2-oxobutanoic acid + L-Glutamate <=> L-Methionine + 2-Oxoglutarate R07397 UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan; 4IV-alpha-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 3-beta-D-Glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + alpha-N-Acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosylproteoglycan R07398 glycoprotein-phosphatidylinositol phosphatidohydrolase; 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol + Phosphatidate R07399 Acetyl-CoA + Pyruvate + H2O <=> (R)-2-Methylmalate + CoA R07400 cephalosporin C:oxygen oxidoreductase (deaminating); Cephalosporin C + H2O + Oxygen <=> (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Ammonia + Hydrogen peroxide R07401 (7R)-7-(5-Carboxy-5-oxopentanoyl)aminocephalosporinate + Hydrogen peroxide <=> (7R)-7-(4-Carboxybutanamido)cephalosporanate + CO2 + H2O R07402 (7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase; (7R)-7-(4-Carboxybutanamido)cephalosporanate + H2O <=> 7-Aminocephalosporanic acid + Glutarate R07403 indole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating); Indole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Indolin-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O R07404 5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming); ATP + Aminoimidazole ribotide + HCO3- <=> ADP + Orthophosphate + 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole R07405 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase; 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate R07406 2-Amino-3-oxo-4-phosphonooxybutyrate <=> 3-Amino-2-oxopropyl phosphate + CO2 R07407 L-aspartate:NADP+ oxidoreductase (deaminating); L-Aspartate + NADP+ <=> Iminoaspartate + NADPH + H+ R07409 choline,reduced-ferredoxin:oxygen oxidoreductase; Choline + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Betaine aldehyde + 2 H2O + 2 Oxidized ferredoxin R07410 L-aspartate:NAD+ oxidoreductase (deaminating); L-Aspartate + NAD+ <=> Iminoaspartate + NADH + H+ R07411 (2E,6E)-farnesyl-diphosphate:protoheme IX farnesyltranstransferase; Heme + H2O + trans,trans-Farnesyl diphosphate <=> Heme O + Diphosphate R07412 ferroheme o:acceptor C-81-oxidoreductase (heme a-forming); Heme O + H2O + 2 Acceptor <=> Heme A + 2 Reduced acceptor R07413 Digalacturonate + H2O <=> 2 D-Galacturonate R07414 glutamate putrescine ligase; ATP + L-Glutamate + Putrescine <=> ADP + Orthophosphate + gamma-L-Glutamylputrescine R07415 gamma-L-Glutamylputrescine + H2O + Oxygen <=> gamma-Glutamyl-gamma-aminobutyraldehyde + Ammonia + Hydrogen peroxide R07416 N-methylanthranilate:CoA ligase (AMP-forming); ATP + N-Methylanthranilate + CoA <=> AMP + Diphosphate + N-Methylanthraniloyl-CoA R07417 4-(gamma-L-glutamylamino)butanal:NAD+ oxidoreductase; gamma-Glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADH + H+ R07418 4-(gamma-L-glutamylamino)butanal:NADP+ oxidoreductase; gamma-Glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(L-gamma-Glutamylamino)butanoate + NADPH + H+ R07419 4-(gamma-L-glutamylamino)butanoate amidohydrolase; 4-(L-gamma-Glutamylamino)butanoate + H2O <=> 4-Aminobutanoate + L-Glutamate R07420 Phosphocreatine <=> Creatinine + Orthophosphate R07421 indolin-2-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); Indolin-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Hydroxyindolin-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O R07422 3-hydroxyindolin-2-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming); 3-Hydroxyindolin-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> HBOA + [Oxidized NADPH---hemoprotein reductase] + H2O R07423 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); HBOA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> DIBOA + [Oxidized NADPH---hemoprotein reductase] + H2O R07426 UDP-glucose:DIBOA 2-D-glucosyltransferase; UDP-glucose + DIBOA <=> UDP + DIBOA-glucoside R07427 delta5-3-ketosteroid isomerase; Campesterol <=> Campest-4-en-3beta-ol R07428 3-beta-hydroxysteroid dehydrogenase; Campest-4-en-3beta-ol + NAD+ <=> Campest-4-en-3-one + NADH + H+ R07429 5alpha-campestan-3-one:NADP+ delta4-oxidoreductase; Campest-4-en-3-one + NADPH + H+ <=> 5alpha-Campestan-3-one + NADP+ R07430 6-oxocampestanol,NADPH:brassinosteroid C22alpha-hydroxylase; 6-Oxocampestanol + Oxygen + NADPH <=> Cathasterone + NADP+ + H2O R07431 6-deoxo-cathasterone:brassinosteroid C23alpha-hydroxylase; Cathasterone + Oxygen + Reduced acceptor <=> Teasterone + H2O + Acceptor R07432 p-coumaroyl-CoA:quinate hydroxycinnamoyltransferase; p-Coumaroyl-CoA + Quinate <=> CoA + p-Coumaroyl quinic acid R07433 5-O-caffeoylshikimic acid:shikimate hydroxycinnamoyltransferase; 5-O-Caffeoylshikimic acid + CoA <=> Caffeoyl-CoA + Shikimate R07436 p-coumaroyl-CoA:caffeoyl-CoA 3-hydroxylase; p-Coumaroyl-CoA <=> Caffeoyl-CoA R07437 4-coumaryl alcohol:NADP+ oxidoreductase; 4-Hydroxycinnamyl aldehyde + NADPH + H+ <=> 4-Coumaryl alcohol + NADP+ R07440 Ferulate + NADPH + H+ + Oxygen <=> 5-Hydroxyferulic acid + NADP+ + H2O R07441 sinapoyl aldehyde:NAD oxidoreductase; Sinapoyl aldehyde + NAD+ + H2O <=> Sinapate + NADH + H+ R07442 sinapoyl aldehyde:NADP oxidoreductase; Sinapoyl aldehyde + NADP+ + H2O <=> Sinapate + NADPH + H+ R07443 donor:hydrogen-peroxide oxidoreductase; 5-Hydroxyconiferyl alcohol <=> 5-Hydroxy-guaiacyl lignin R07444 teasterone:brassinosteroid C3-oxidoreductase; Teasterone <=> 3-Dehydroteasterone R07445 campesterol,NADPH---hemoprotein reductase:oxygen 22S-oxidoreductase (hydroxylating); Campesterol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 22alpha-Hydroxy-campesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R07446 (22S)-22-hydroxycampesterol,[reduced NADPH-hemoprotein reductase]:oxygen 3-oxidoreductase; 22alpha-Hydroxy-campesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (22S)-22-Hydroxycampest-4-en-3-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07447 22alpha-hydroxy-5alpha-campestan-3-one:NADP+ delta4-oxidoreductase; (22S)-22-Hydroxycampest-4-en-3-one + NADPH + H+ <=> 22alpha-Hydroxy-5alpha-campestan-3-one + NADP+ R07448 6-deoxocathasterone:brassinosteroid C23alpha-hydroxylase; 6-Deoxocathasterone + Oxygen <=> 6-Deoxoteasterone + H2O R07449 6-deoxoteasterone:brassinosteroid C3-oxidoreductase; 6-Deoxoteasterone <=> 3-Dehydro-6-deoxoteasterone R07450 6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (6alpha-hydroxylating); 6-Deoxocastasterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 6alpha-Hydroxycastasterone + H2O + [Oxidized NADPH---hemoprotein reductase] R07451 6alpha-hydroxy-castasterone,NADPH---hemoprotein reductase:oxygen 6-oxidoreductase; 6alpha-Hydroxycastasterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Castasterone + 2 H2O + [Oxidized NADPH---hemoprotein reductase] R07452 campest-4-en-3-one,NADPH---hemoprotein reductase:oxygen 22S-oxidoreductase (hydroxylating); Campest-4-en-3-one + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (22S)-22-Hydroxycampest-4-en-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O R07453 5alpha-campestan-3-one,NADPH---hemoprotein reductase:oxygen 22S-oxidoreductase (hydroxylating); 5alpha-Campestan-3-one + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 22alpha-Hydroxy-5alpha-campestan-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O R07454 campestanol,NADPH---hemoprotein reductase:oxygen 22S-oxidoreductase (hydroxylating); Campestanol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 6-Deoxocathasterone + [Oxidized NADPH---hemoprotein reductase] + H2O R07455 6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (teasterone-forming); 6-Deoxoteasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Teasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase] R07456 D-ribulose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase; D-Glyceraldehyde 3-phosphate + D-Ribulose 5-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + Orthophosphate + 3 H2O R07457 3-dehydro-6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (3-dehydroteasterone-forming); 3-Dehydro-6-deoxoteasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> 3-Dehydroteasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase] R07458 6-deoxotyphasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (typhasterol-forming); 6-Deoxotyphasterol + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Typhasterol + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase] R07459 ATP:[sulfur-carrier protein] adenylyltransferase; Sulfur-carrier protein + ATP <=> Adenylyl-[sulfur-carrier protein] + Diphosphate R07460 L-cysteine:[enzyme]-cysteine sulfurtransferase; [Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine R07461 [enzyme]-S-sulfanyl-L-cysteine:adenylyl-[sulfur-carrier protein] sulfurtransferase; [Enzyme]-S-sulfanylcysteine + Adenylyl-[sulfur-carrier protein] + Reduced acceptor <=> AMP + Thiocarboxy-[sulfur-carrier protein] + [Enzyme]-cysteine + Acceptor R07463 glycine:oxygen oxidoreductase; Glycine + Oxygen <=> Iminoglycine + Hydrogen peroxide R07466 5alpha-Campestan-3-one <=> Campestanol R07467 Campestanol + Oxygen + Reduced acceptor <=> 6alpha-Hydroxycampestanol + H2O + Acceptor R07468 6alpha-Hydroxycampestanol <=> 6-Oxocampestanol R07469 3-Dehydroteasterone <=> Typhasterol R07470 typhasterol,NADPH:oxygen oxidoreductase (2alpha-hydroxylating); Typhasterol + NADPH + H+ + Oxygen <=> Castasterone + NADP+ + H2O R07471 castasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, brassinolide-forming); Castasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Brassinolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07472 22alpha-Hydroxy-5alpha-campestan-3-one <=> 6-Deoxocathasterone R07473 3-Dehydro-6-deoxoteasterone <=> 6-Deoxotyphasterol R07474 6-deoxotyphasterol,NADPH:oxygen oxidoreductase (2alpha-hydroxylating); 6-Deoxotyphasterol + NADPH + H+ + Oxygen <=> 6-Deoxocastasterone + NADP+ + H2O R07475 geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase; Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> all-trans-Pentaprenyl diphosphate + Diphosphate R07476 (2R)-O-phospho-3-sulfolactate sulfo-lyase; (2R)-O-Phospho-3-sulfolactate <=> Sulfite + Phosphoenolpyruvate R07477 spermidine:NAD+ oxidoreductase; Spermidine + NAD+ <=> Dehydrospermidine + NADH + H+ R07478 [eIF5A-precursor]-deoxyhypusine:NAD+ oxidoreductase; N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+ R07479 dehydrospermidine:[enzyme]-lysine N-4-aminobutylidenetransferase; Dehydrospermidine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + 1,3-Diaminopropane R07480 N-(4-aminobutylidene)-[enzyme]-lysine:[eIF5A-precursor]-lysine N-4-aminobutylidenetransferase; N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine R07481 Cycloartenol + S-Adenosyl-L-methionine <=> 24-Methylidenecycloartanol + S-Adenosyl-L-homocysteine R07483 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ <=> 4alpha-Methylfecosterol + NADP+ R07484 4alpha-Methylfecosterol <=> 24-Methylenelophenol R07486 delta7-avenasterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating; Delta7-Avenasterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroavenasterol + 2 Ferricytochrome b5 + 2 H2O R07487 5-Dehydroavenasterol <=> Isofucosterol R07488 Isofucosterol + NADPH + H+ <=> beta-Sitosterol + NADP+ R07489 beta-sitosterol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating); beta-Sitosterol + NADPH + H+ + Oxygen <=> Stigmasterol + NADP+ + 2 H2O R07491 episterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating; Episterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroepisterol + 2 Ferricytochrome b5 + 2 H2O R07492 5-Dehydroepisterol <=> 24-Methylenecholesterol R07493 24-Methylenecholesterol + NADPH + H+ <=> Campesterol + NADP+ R07494 4alpha-Methylzymosterol-4-carboxylate + NADP+ <=> 3-Keto-4-methylzymosterol + NADPH + H+ + CO2 R07495 4alpha-methylzymosterol:NADP+ 3-oxidoreductase; 3-Keto-4-methylzymosterol + NADPH + H+ <=> 4alpha-Methylzymosterol + NADP+ R07497 Fecosterol <=> Episterol R07498 Zymosterol + NADPH + H+ <=> 5alpha-Cholest-8-en-3beta-ol + NADP+ R07499 14-Demethyllanosterol + NADPH + H+ <=> 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ R07500 phytyl-diphosphate:homogentisate phytyltransferase (decarboxylating); Phytyl diphosphate + Homogentisate <=> 2-Methyl-6-phytylquinol + Diphosphate + CO2 R07501 S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C3-methyltransferase; 2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine <=> 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine R07502 gamma-tocopherol lyase (decyclizing); 2,3-Dimethyl-5-phytylquinol <=> gamma-Tocopherol R07503 delta-tocopherol lyase (decyclizing); 2-Methyl-6-phytylquinol <=> delta-Tocopherol R07504 S-adenosyl-L-methionine:delta-tocopherol 5-O-methyltransferase; delta-Tocopherol + S-Adenosyl-L-methionine <=> beta-Tocopherol + S-Adenosyl-L-homocysteine R07506 ergosta-5,7,24(28)-trien-3beta-ol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating); 5-Dehydroepisterol + NADPH + H+ + Oxygen <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O R07507 7-Dehydrodesmosterol + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+ R07508 beta-Tocopherol <=> alpha-Tocopherol R07509 14-demethyllanosterol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 14-Demethyllanosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Methylzymosterol-4-carboxylate + 6 Ferricytochrome b5 + 4 H2O R07510 15-cis-Phytoene <=> 9,9'-dicis-zeta-Carotene R07511 9,9'-dicis-zeta-carotene:quinone oxidoreductase; 9,9'-dicis-zeta-Carotene + 2 Quinone <=> 7,9,7',9'-tetracis-Lycopene + 2 Hydroquinone R07512 7,9,7',9'-tetracis-lycopene cis-trans-isomerase; 7,9,7',9'-tetracis-Lycopene <=> Lycopene R07513 17-O-acetylajmaline O-acetylhydrolase; 17-O-Acetylajmaline + H2O <=> Ajmaline + Acetate R07514 6-hydroxypseudooxynicotinemonooxygenase; 6-Hydroxypseudooxynicotine + Acceptor + H2O <=> 2,6-Dihydroxypseudooxynicotine + Reduced acceptor R07515 2,6-dihydroxypseudooxynicotine hydrolase; 2,6-Dihydroxypseudooxynicotine + H2O <=> 2,6-Dihydroxypyridine + 4-Methylaminobutyrate R07516 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); gamma-Carotene + H2O <=> 1'-Hydroxy-gamma-carotene R07517 1'-Hydroxy-gamma-carotene <=> 1'-Hydroxytorulene R07518 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming); Lycopene + Reduced acceptor + Oxygen <=> 3,4-Dehydrolycopene + Acceptor + H2O R07519 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); Lycopene + H2O <=> 1-Hydroxy-1,2-dihydrolycopene R07520 1-hydroxy-1,2-dihydrolycopene:acceptor oxidoreductase; 1-Hydroxy-1,2-dihydrolycopene + Acceptor <=> 3,4-Dehydrorhodopin + Reduced acceptor R07521 S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase; 3,4-Dehydrorhodopin + S-Adenosyl-L-methionine <=> Anhydrorhodovibrin + S-Adenosyl-L-homocysteine R07522 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); Anhydrorhodovibrin + H2O <=> Rhodovibrin R07523 1-hydroxy-1,2-dihydrolycopene:acceptor oxidoreductase; Rhodovibrin <=> Hydroxyspirilloxanthin R07524 S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase; Hydroxyspirilloxanthin + S-Adenosyl-L-methionine <=> Spirilloxanthin + S-Adenosyl-L-homocysteine R07525 spirilloxanthin,reduced-ferredoxin:oxygen oxidoreductase (spirilloxanthin-2-one-forming); Spirilloxanthin + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> 2-Ketospirilloxanthin + 3 H2O + 4 Oxidized ferredoxin R07526 2-oxospirilloxanthin,reduced-ferredoxin:oxygen oxidoreductase (2-oxospirilloxanthin-2-one-forming); 2-Ketospirilloxanthin + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> 2,2'-Diketospirilloxanthin + 3 H2O + 4 Oxidized ferredoxin R07527 S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase; 1-Hydroxy-1,2-dihydrolycopene + S-Adenosyl-L-methionine <=> 3,4-Dihydroanhydrorhodovibrin + S-Adenosyl-L-homocysteine R07528 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); 3,4-Dihydroanhydrorhodovibrin + H2O <=> 3',4'-Dihydrorhodovibrin R07529 S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase; 3',4'-Dihydrorhodovibrin + S-Adenosyl-L-methionine <=> 3,4,3',4'-Tetrahydrospirilloxanthin + S-Adenosyl-L-homocysteine R07530 alpha-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; alpha-Carotene + 2 Reduced ferredoxin + H+ + Oxygen <=> Zeinoxanthin + 2 Oxidized ferredoxin + H2O R07531 zeinoxanthin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); Zeinoxanthin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Lutein + [Oxidized NADPH---hemoprotein reductase] + H2O R07532 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); all-trans-Neurosporene + H2O <=> Chloroxanthin R07533 demethylspheroidene O-methyltransferase; Chloroxanthin + S-Adenosyl-L-methionine <=> 3,4-Dihydrospheroidene + S-Adenosyl-L-homocysteine R07534 1-hydroxy-1,2-dihydrolycopene:acceptor oxidoreductase; Chloroxanthin <=> Demethylspheroidene R07535 S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase; Demethylspheroidene + S-Adenosyl-L-methionine <=> Spheroidene + S-Adenosyl-L-homocysteine R07536 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); Spheroidene + H2O <=> Hydroxyspheroidene R07537 spheroidene,reduced-ferredoxin:oxygen oxidoreductase (spheroiden-2-one-forming); Spheroidene + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> Spheroidenone + 3 H2O + 4 Oxidized ferredoxin R07538 Hydroxyspheroidene + 2 Oxygen + 4 Reduced ferredoxin + 4 H+ <=> Hydroxyspheroidenone + 3 H2O + 4 Oxidized ferredoxin R07539 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); Spheroidenone + H2O <=> Hydroxyspheroidenone R07540 gamma-Carotene <=> 1',2'-Dihydro-gamma-carotene R07541 gamma-carotene:acceptor oxidoreductase/methyltranferase (phi-ring forming); gamma-Carotene + 2 Acceptor <=> Chlorobactene + 2 Reduced acceptor R07542 gamma-Carotene <=> 1',2'-Dihydrochlorobactene R07543 lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); Chlorobactene + H2O <=> Hydroxychlorobactene R07544 Hydroxychlorobactene <=> Hydroxychlorobactene glucoside R07545 Hydroxychlorobactene glucoside <=> Hydroxychlorobactene glucoside ester R07546 1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-gamma-carotene glucoside R07547 1'-Hydroxy-gamma-carotene glucoside <=> 1'-Hydroxy-gamma-carotene glucoside ester R07548 gamma-Carotene <=> Myxol R07549 Myxol <=> 4-Ketomyxol R07550 Myxol <=> 4-Hydroxymyxol R07551 4-Ketomyxol <=> 4-Hydroxymyxol R07552 gamma-Carotene <=> Deoxymyxol R07553 Deoxymyxol <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) R07554 (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) <=> (3R,2'S)-Myxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) R07555 gamma-Carotene <=> (2'S)-Deoxymyxol 2'-alpha-L-fucoside R07556 (2'S)-Deoxymyxol 2'-alpha-L-fucoside <=> (3R,2'S)-Myxol 2'-alpha-L-fucoside R07557 (3R,2'S)-myxol 2'-alpha-L-fucoside,donor:oxygen oxidoreductase; (3R,2'S)-Myxol 2'-alpha-L-fucoside + 2 Reduced acceptor + 2 Oxygen <=> (3S,2'S)-4-Ketomyxol 2'-alpha-L-fucoside + 2 Acceptor + 3 H2O R07558 beta-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; beta-Carotene + 2 Reduced ferredoxin + H+ + Oxygen <=> beta-Cryptoxanthin + 2 Oxidized ferredoxin + H2O R07559 beta-cryptoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; beta-Cryptoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Zeaxanthin + 2 Oxidized ferredoxin + H2O R07560 beta-carotene:acceptor oxidoreductase/methyltranferase (phi-ring forming); beta-Carotene + 4 Acceptor <=> Isorenieratene + 4 Reduced acceptor R07561 echinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; Echinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> 3'-Hydroxyechinenone + 2 Oxidized ferredoxin + H2O R07562 echinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; Echinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> 3-Hydroxyechinenone + 2 Oxidized ferredoxin + H2O R07563 echinenone,donor:oxygen oxidoreductase (canthaxanthin-forming); Echinenone + 2 Reduced acceptor + 2 Oxygen <=> Canthaxanthin + 2 Acceptor + 3 H2O R07564 beta-cryptoxanthin,donor:oxygen oxidoreductase (3'-hydroxyechinenone-forming); beta-Cryptoxanthin + 2 Reduced acceptor + 2 Oxygen <=> 3'-Hydroxyechinenone + 2 Acceptor + 3 H2O R07565 beta-cryptoxanthin,donor:oxygen oxidoreductase (3-hydroxyechinenone-forming); beta-Cryptoxanthin + 2 Reduced acceptor + 2 Oxygen <=> 3-Hydroxyechinenone + 2 Acceptor + 3 H2O R07566 3'-hydroxyechinenone,donor:oxygen oxidoreductase (phoenicoxanthin-forming); 3'-Hydroxyechinenone + 2 Reduced acceptor + 2 Oxygen <=> Phoenicoxanthin + 2 Acceptor + 3 H2O R07567 3-hydroxyechinenone,donor:oxygen oxidoreductase (phoenicoxanthin-forming); 3-Hydroxyechinenone + 2 Reduced acceptor + 2 Oxygen <=> Phoenicoxanthin + 2 Acceptor + 3 H2O R07568 canthaxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; Canthaxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Phoenicoxanthin + 2 Oxidized ferredoxin + H2O R07569 3'-hydroxyechinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; 3'-Hydroxyechinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> Adonixanthin + 2 Oxidized ferredoxin + H2O R07570 3-hydroxyechinenone,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; 3-Hydroxyechinenone + 2 Reduced ferredoxin + H+ + Oxygen <=> Adonixanthin + 2 Oxidized ferredoxin + H2O R07571 zeaxanthin,donor:oxygen oxidoreductase (adonixanthin-forming); Zeaxanthin + 2 Reduced acceptor + 2 Oxygen <=> Adonixanthin + 2 Acceptor + 3 H2O R07572 phoenicoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3'-oxidoreductase; Phoenicoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Astaxanthin + 2 Oxidized ferredoxin + H2O R07573 adonixanthin,donor:oxygen oxidoreductase (astaxanthin-forming); Adonixanthin + 2 Reduced acceptor + 2 Oxygen <=> Astaxanthin + 2 Acceptor + 3 H2O R07574 UDP-glucose:zeaxanthin beta-D-glucosyltransferase; Zeaxanthin + 2 UDP-glucose <=> Zeaxanthin diglucoside + 2 UDP R07575 UDP-D-glucose:abscisate beta-D-glucosyltransferase; Abscisate + UDP-glucose <=> Abscisic acid glucose ester + UDP R07576 8'-Hydroxyabscisate <=> Phaseic acid R07577 Phaseic acid <=> Dihydrophaseic acid R07578 beta-Cryptoxanthin <=> Thermocryptoxanthin R07579 Thermocryptoxanthin <=> Thermozeaxanthin R07580 Zeaxanthin <=> Thermozeaxanthin R07581 Thermozeaxanthin <=> Thermobiszeaxanthin R07582 (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase; (9S,10S)-10-Hydroxy-9-(phosphonooxy)octadecanoate + H2O <=> (9S,10S)-9,10-Dihydroxyoctadecanoate + Orthophosphate R07583 myo-inositol-hexakisphosphate 5-phosphohydrolase; Phytic acid + H2O <=> 1L-myo-Inositol 1,2,3,4,6-pentakisphosphate + Orthophosphate R07597 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase; Cholesterol-5alpha,6alpha-epoxide + H2O <=> 3beta,5alpha,6beta-Cholestanetriol R07598 L-lysine:oxygen 6-oxidoreductase (deaminating); L-Lysine + Oxygen + H2O <=> L-2-Aminoadipate 6-semialdehyde + Hydrogen peroxide + Ammonia R07599 3-Methyl-2-oxobutanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxypropyl-ThPP + CO2 R07600 2-Methyl-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + Thiamin diphosphate R07601 4-Methyl-2-oxopentanoate + Thiamin diphosphate <=> 3-Methyl-1-hydroxybutyl-ThPP + CO2 R07602 3-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate R07603 (S)-3-Methyl-2-oxopentanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2 R07604 2-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate R07605 7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase; 7-Aminomethyl-7-carbaguanine + 2 NADP+ <=> 7-Cyano-7-carbaguanine + 2 NADPH + 2 H+ R07606 L-methionine:thioredoxin-disulfide S-oxidoreductase; L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (S)-S-oxide + Thioredoxin R07607 peptide-methionine:thioredoxin-disulfide S-oxidoreductase; Peptide-L-methionine + Thioredoxin disulfide + H2O <=> Peptide-L-methionine (R)-S-oxide + Thioredoxin R07608 L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming]; L-Methionine + Thioredoxin disulfide + H2O <=> L-Methionine (R)-S-oxide + Thioredoxin R07609 UDP-N-acetyl-D-galactosamine + Sda antigen - related compound <=> UDP + Sda antigen R07610 UDP-N-acetyl-D-galactosamine + G00388 <=> UDP + G05309 R07611 UDP-N-acetyl-D-galactosamine + G05309 <=> UDP + G00704 R07612 reactive-black-5:hydrogen-peroxide oxidoreductase; Reactive black 5 + Hydrogen peroxide <=> Oxidized reactive black 5 + 2 H2O R07613 LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase; LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate <=> 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O R07614 UDP-N-acetyl-D-galactosamine + G00025 <=> UDP + G13023 R07615 UDP-N-acetyl-D-galactosamine + G01977 <=> UDP + G13024 R07616 UDP-N-acetyl-D-galactosamine + G01941 <=> UDP + G13025 R07617 UDP-D-galactose + G00025 <=> UDP + G11136 R07618 enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase; Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+ R07619 UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13026 R07620 Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027 R07621 UDP-N-acetyl-D-glucosamine + G13026 <=> UDP + G13028 R07622 UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G10818 R07623 UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G13030 R07624 UDP-N-acetyl-D-glucosamine + G10818 <=> UDP + G13029 R07625 UDP-N-acetyl-D-glucosamine + G13030 <=> UDP + G13029 R07626 protein-omega-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase; Protein-omega-N-(ADP-D-ribosyl)-L-arginine + H2O <=> ADP-ribose + Protein-L-arginine R07627 cis-stilbene-oxide hydrolase; cis-Stilbene oxide + H2O <=> (+)-(1R,2R)-1,2-Diphenylethane-1,2-diol R07628 UDP-D-galactose + G00031 <=> UDP + G00032 R07629 3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming); 3-Oxo-3-ureidopropanoate + H2O <=> Malonate + Urea R07630 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming); trans,trans-Farnesyl diphosphate <=> Amorpha-4,11-diene + Diphosphate R07631 geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming]; Geranyl diphosphate + H2O <=> (+)-Linalool + Diphosphate R07632 geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming]; Geranyl diphosphate + H2O <=> (-)-Linalool + Diphosphate R07633 3-sulfolactate bisulfite-lyase; (2R)-3-Sulfolactate <=> Pyruvate + HSO3- R07634 L-cysteate bisulfite-lyase (deaminating); L-Cysteate + H2O <=> Pyruvate + HSO3- + Ammonia R07635 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming); 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol <=> 6-(alpha-D-Glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol R07636 FAD AMP-lyase (cyclic-FMN-forming); FAD <=> AMP + Riboflavin cyclic-4',5'-phosphate R07638 (Z)-phenylacetaldehyde-oxime hydro-lyase; (Z)-Phenylacetaldehyde oxime <=> Phenylacetonitrile + H2O R07639 decenoyl-[acyl-carrier-protein] Delta2-trans-Delta3-cis-isomerase; trans-Dec-2-enoyl-[acp] <=> cis-Dec-3-enoyl-[acp] R07640 poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming); ATP + RNA(n) + RNA(m) <=> AMP + Diphosphate + RNA(n+m) R07641 2 ATP + HCO3- + Ammonia <=> 2 ADP + Orthophosphate + Carbamoyl phosphate R07642 L-amino acid:L-amino acid ligase (ADP-forming); ATP + L-Amino acid + L-Amino acid <=> ADP + Orthophosphate + L-Aminoacyl-L-amino acid R07643 L-glutamate:histamine ligase; ATP + L-Glutamate + Histamine <=> Products of ATP breakdown + N(alpha)-gamma-L-Glutamylhistamine R07644 2,3-dihydroxybenzoate:L-serine ligase; 6 ATP + 3 2,3-Dihydroxybenzoate + 3 L-Serine <=> Enterochelin + 6 AMP + 6 Diphosphate R07646 L-lysine:tRNAPyl ligase (AMP-forming); ATP + L-Lysine + tRNA(Pyl) <=> AMP + Diphosphate + L-Lysyl-tRNA(Pyl) R07647 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + Diphosphate R07648 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-germacrene D-forming]; trans,trans-Farnesyl diphosphate <=> (-)-Germacrene D + Diphosphate R07649 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming); trans,trans-Farnesyl diphosphate <=> (+)-Germacrene A + Diphosphate R07650 L-2,4-diaminobutanoate carboxy-lyase; L-2,4-Diaminobutanoate <=> 1,3-Diaminopropane + CO2 R07651 D-Ala-D-Ala dipeptidase; D-Alanyl-D-alanine + H2O <=> 2 D-Alanine R07652 farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase (4,4'-diapophytoene forming); 2 trans,trans-Farnesyl diphosphate <=> 4,4'-Diapophytoene + 2 Diphosphate R07653 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diapophytoene + 3 FAD <=> 4,4'-Diaponeurosporene + 3 FADH2 R07654 4,4'-diaponeurosporene,AH2:oxygen 4-oxidoreductase; 4,4'-Diaponeurosporene + 3 Reduced acceptor + 3 Oxygen <=> 4,4'-Diaponeurosporenic acid + 3 Acceptor + 4 H2O R07655 4,4'-diaponeurosporenoate glucosyltransferase; 4,4'-Diaponeurosporenic acid <=> Glucosyl-4,4'-diaponeurosporenoate R07656 Glucosyl-4,4'-diaponeurosporenoate <=> Staphyloxanthin R07657 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing); 1-Hydroxy-2-naphthoate + Oxygen <=> (3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate R07658 UDP-glucuronate + NAD+ <=> UDP-L-Ara4O + CO2 + NADH + H+ R07659 UDP-L-Ara4O + L-Glutamate <=> UDP-L-Ara4N + 2-Oxoglutarate R07660 10-Formyltetrahydrofolate + UDP-L-Ara4N <=> Tetrahydrofolate + UDP-L-Ara4FN R07661 UDP-4-deoxy-4-formamido-L-arabinose:undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinosyltransferase; UDP-L-Ara4FN + di-trans,poly-cis-Undecaprenyl phosphate <=> Undecaprenyl phosphate alpha-L-Ara4FN + UDP R07662 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol amidohydrolase; Undecaprenyl phosphate alpha-L-Ara4FN + H2O <=> Undecaprenyl phosphate alpha-L-Ara4N + Formate R07663 Toluene-4-sulfonate + Oxygen <=> 4-Cresol + Sulfate R07664 (S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase; (S)-Mandelate + FMN <=> alpha-Oxo-benzeneacetic acid + Reduced FMN R07665 3-Cresol + Oxygen + NADH + H+ <=> 3-Hydroxybenzyl alcohol + NAD+ + H2O R07666 3-hydroxybenzaldehyde:NADP+ oxidoreductase; 3-Hydroxybenzaldehyde + NADP+ + H2O <=> 3-Hydroxybenzoate + NADPH + H+ R07667 3-hydroxybenzaldehyde:NAD+ oxidoreductase; 3-Hydroxybenzaldehyde + NAD+ + H2O <=> 3-Hydroxybenzoate + NADH + H+ R07668 Vanillate + Cob(I)alamin <=> 3,4-Dihydroxybenzoate + Methylcobalamin R07669 beta-hexachlorocyclohexane halidohydrolase; beta-1,2,3,4,5,6-Hexachlorocyclohexane + H2O <=> beta-2,3,4,5,6-Pentachlorocyclohexanol + Hydrochloric acid R07670 beta-2,3,4,5,6-pentachlorocyclohexanol halidohydrolase; beta-2,3,4,5,6-Pentachlorocyclohexanol + H2O <=> beta-2,3,5,6-Tetrachloro-1,4-cyclohexanediol + Hydrochloric acid R07671 Protein N(pi)-phospho-L-histidine + Ascorbate <=> Protein histidine + L-Ascorbate 6-phosphate R07672 GDP-mannose 5-epimerase; GDP-mannose <=> GDP-L-gulose R07673 GDP-L-gulose <=> GDP-L-galactose R07674 beta-L-galactose-1-phosphate phosphohydrolase; beta-L-Galactose 1-phosphate + H2O <=> L-Galactose + Orthophosphate R07675 L-galactose:NAD+ 1-oxidoreductase; L-Galactose + NAD+ <=> L-Galactono-1,4-lactone + NADH + H+ R07676 L-galactonate:NADP+ oxidoreductase; L-Galactonate + NADP+ <=> D-Galacturonate + NADPH + H+ R07677 L-Ascorbate 6-phosphate + H2O <=> 3-Dehydro-L-gulonate 6-phosphate R07678 GDP-beta-L-galactose:hexose 1-phosphate guanylyltransferase; GDP-L-galactose + D-Mannose 1-phosphate <=> beta-L-Galactose 1-phosphate + GDP-mannose R07679 Ascorbate + 2 Ferricytochrome c <=> Dehydroascorbate + 2 Ferrocytochrome c + 2 H+ R07680 L-Galactono-1,4-lactone + H2O <=> L-Galactonate R07682 naphthalene disulfonate 1,2-dioxygenase; 1,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite R07683 naphthalene disulfonate 1,2-dioxygenase; 2,6-Naphthalenedisulfonic acid + Oxygen <=> 1,2-Dihydroxynaphthalene-6-sulfonate + Sulfite R07684 1,2-Dihydroxynaphthalene-6-sulfonate + Oxygen <=> (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate R07685 (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate + 2 H2O <=> 5-Sulfosalicylate + Pyruvate R07686 5-Sulfosalicylate + Oxygen <=> 2,5-Dihydroxybenzoate + Sulfate R07687 Anthracene + Oxygen + 2 H+ + 2 e- <=> Anthracene-9,10-dihydrodiol R07688 Anthracene-9,10-dihydrodiol <=> 9,10-Dihydroxyanthracene + 2 H+ R07689 9,10-Dihydroxyanthracene <=> Anthraquinone + 2 H+ R07690 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate <=> 1,2-Dihydrophthalic acid R07691 3-Hydroxy-2-naphthoate + Oxygen <=> 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate R07692 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid + 2 H2O <=> 3-Hydroxy-2-naphthoate + Pyruvate R07693 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid <=> 6,7-Benzocoumarin R07694 1,2-Anthracenediol <=> 1-Methoxy-2-hydroxyanthracene R07695 2,3-Dihydroxynaphthalene <=> Salicylate R07696 3-Hydroxy-2-naphthoate <=> 2,3-Dihydroxynaphthalene R07697 Phenylboronic acid + Oxygen <=> Phenol + Boric acid R07698 naphthalene disulfonate 1,2-dioxygenase; 1-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite R07699 naphthalene disulfonate 1,2-dioxygenase; 2-Naphthalenesulfonic acid + Oxygen <=> Naphthalene-1,2-diol + Sulfite R07700 aniline dioxygenase; Aniline + Oxygen <=> Catechol + Ammonia R07701 1,2-Anthracenediol + Oxygen <=> 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid R07702 1,2-Anthracenediol + Oxygen <=> 3-(2-Carboxyvinyl)naphthalene-2-carboxylic acid R07703 1,2-dihydrophthalic acid:NAD+ oxidoreductase; 1,2-Dihydrophthalic acid + NAD+ <=> Phthalate + NADH + H+ R07704 anthracene,NADH:oxygen oxidoreductase (1,2-hydroxylating); Anthracene + Oxygen + NADH + H+ <=> Anthracene-cis-1,2-dihydrodiol + NAD+ R07705 anthracene cis-1,2-dihydrodiol:NAD+ 1,2-oxidoreductase; Anthracene-cis-1,2-dihydrodiol + NAD+ <=> 1,2-Anthracenediol + NADH + H+ R07706 nitrobenzene 1,2-dioxygenase; Nitrobenzene + Oxygen + NADH + H+ <=> Catechol + Nitrite + NAD+ R07707 Phenanthrene-9,10-oxide <=> 9-Hydroxyphenanthrene R07708 trans-9(S),10(S)-Dihydrodiolphenanthrene <=> 9-Hydroxyphenanthrene + H2O R07709 salicylate,NADH:oxygen oxidoreductase (5-hydroxylating); Salicylate + NADH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NAD+ + H2O R07710 salicylate,NADPH:oxygen oxidoreductase (5-hydroxylating); Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O R07711 Liquiritigenin + NADPH + H+ + Oxygen <=> 6,7,4'-Trihydroxyflavanone + NADP+ + H2O R07712 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Liquiritigenin + 2-Oxoglutarate + Oxygen <=> 7,4'-Dihydroxyflavone + Succinate + CO2 + H2O R07713 (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming); (3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate + H2O <=> 2-Carboxybenzaldehyde + Pyruvate R07714 7,4'-Dihydroxyflavone + 2 NADPH + 2 H+ + Oxygen <=> 2,7,4'-Trihydroxyisoflavanone + 2 NADP+ + H2O R07715 6,7,4'-trihydroxyflavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration); 6,7,4'-Trihydroxyflavanone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2,6,7,4'-Tetrahydroxyisoflavanone + H2O + [Oxidized NADPH---hemoprotein reductase] R07716 2,6,7,4'-Tetrahydroxyisoflavanone <=> 4',6,7-Trihydroxyisoflavone R07717 4',6,7-Trihydroxyisoflavone <=> Glycitein R07718 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; Glycitein + UDP-glucose <=> Glycitin + UDP R07719 malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Glycitin + Malonyl-CoA <=> Malonylglycitin + CoA R07720 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; Daidzein + UDP-glucose <=> Daidzin + UDP R07721 malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Daidzin + Malonyl-CoA <=> Malonyldaidzin + CoA R07722 S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase; S-Adenosyl-L-methionine + 2,7,4'-Trihydroxyisoflavanone <=> S-Adenosyl-L-homocysteine + 2,7-Dihydroxy-4'-methoxyisoflavanone R07723 2,7-dihydroxy-4'-methoxyisoflavanone hydro-lyase (formononetin-forming); 2,7-Dihydroxy-4'-methoxyisoflavanone <=> Formononetin + H2O R07724 S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase; Daidzein + S-Adenosyl-L-methionine <=> Isoformononetin + S-Adenosyl-L-homocysteine R07725 Daidzein <=> Anhydroglycinol R07726 Anhydroglycinol <=> Coumestrol R07727 o-Nitrobenzoate + 2 NADPH + 2 H+ <=> o-Hydroxylaminobenzoate + 2 NADP+ + H2O R07728 (6aR,11aR)-3,9-dihydroxypterocarpan:NADP+ 2'-oxidoreductase; 2'-Hydroxydihydrodaidzein + NADPH + H+ <=> 3,9-Dihydroxypterocarpan + NADP+ + H2O R07729 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; Formononetin + UDP-glucose <=> Ononin + UDP R07730 o-Hydroxylaminobenzoate <=> 3-Hydroxyanthranilate R07731 malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Ononin + Malonyl-CoA <=> Formononetin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA R07732 Formononetin 7-O-(6-O-malonyl-beta-D-glucoside) <=> Ononin R07733 Ononin <=> Formononetin R07734 o-Hydroxylaminobenzoate + 2 H+ <=> Anthranilate + H2O R07735 2'-Hydroxyformononetin <=> 7-Hydroxy-2',4',5'-trimethoxyisoflavone R07736 7-Hydroxy-2',4',5'-trimethoxyisoflavone <=> 9-Demethylmunduserone R07737 (3R,4R)-4'-methoxyisoflavan-2',4,7-triol:NADP+ 4-oxidoreductase; (-)-Vestitone + NADPH + H+ <=> 7,2'-Dihydroxy-4'-methoxy-isoflavanol + NADP+ R07738 4'-methoxyisoflavan-2',4,7-triol hydro-lyase [(-)-medicarpin-forming]; 7,2'-Dihydroxy-4'-methoxy-isoflavanol <=> Medicarpin + H2O R07739 Medicarpin + NADPH + H+ <=> (-)-Vestitol + NADP+ R07740 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; Medicarpin + UDP-glucose <=> (-)-Medicocarpin + UDP R07741 malonyl-CoA:pterocarpan-7-O-beta-D-glucoside 6''-O-malonyltransferase; (-)-Medicocarpin + Malonyl-CoA <=> Medicarpin 3-O-glucoside-6'-malonate + CoA R07742 Medicarpin 3-O-glucoside-6'-malonate <=> (-)-Medicocarpin R07743 (-)-Medicocarpin <=> Medicarpin R07744 Calycosin <=> Rotenone R07745 calycosin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming); Calycosin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pseudobaptigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R07746 pseudobaptigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Pseudobaptigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + [Oxidized NADPH---hemoprotein reductase] + H2O R07747 (+)-sophorol:NADP+ oxidoreductase; 2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (+)-Sophorol + NADP+ R07748 (+)-maackiain:NADP+ 2'-oxidoreductase; (+)-Sophorol + NADPH + H+ <=> (+)-Maackiain + NADP+ + H2O R07749 (+)-Maackiain <=> (+)-6a-Hydroxymaackiain R07750 S-adenosyl-L-methionine:(+)-6a-hydroxymaackiain 3-O-methyltransferase; (+)-6a-Hydroxymaackiain + S-Adenosyl-L-methionine <=> Pisatin + S-Adenosyl-L-homocysteine R07751 (-)-sophorol:NADP+ oxidoreductase; 2',7-Dihydroxy-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (-)-Sophorol + NADP+ R07752 (-)-maackiain:NADP+ 2'-oxidoreductase; (-)-Sophorol + NADPH + H+ <=> (-)-Maackiain + NADP+ + H2O R07753 UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase; (-)-Maackiain + UDP-glucose <=> Trifolirhizin + UDP R07754 malonyl-CoA:pterocarpan-7-O-beta-D-glucoside 6''-O-malonyltransferase; Trifolirhizin + Malonyl-CoA <=> (-)-Maackiain-3-O-glucosyl-6''-O-malonate + CoA R07755 (-)-Maackiain-3-O-glucosyl-6''-O-malonate <=> Trifolirhizin R07756 Trifolirhizin <=> (-)-Maackiain R07757 malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase; Genistin + Malonyl-CoA <=> Malonylgenistin + CoA R07758 Malonyl-CoA + Palmitoyl-CoA <=> 3-Oxostearoyl-CoA + CoA + CO2 R07759 3-hydroxyoctadecanoyl-CoA:NADP+ oxidoreductase; 3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+ R07760 3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O R07761 octadecanoyl-CoA:NADP+ trans-2-oxidoreductase; (2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP+ R07762 Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2 R07763 3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+ R07764 (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] <=> (2E)-Octadecenoyl-[acp] + H2O R07765 octadecanoyl-[acp]:NAD+ trans-2-oxidoreductase; (2E)-Octadecenoyl-[acp] + NADH + H+ <=> Octadecanoyl-[acyl-carrier protein] + NAD+ R07766 octanoyl-[acp]:protein N6-octanoyltransferase; Octanoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> [Protein]-N6-(octanoyl)-L-lysine + Acyl-carrier protein R07767 [protein]-N6-(octanoyl)-L-lysine:an [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase; [Protein]-N6-(octanoyl)-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin R07769 lipoyl-[acp]:protein N6-lipoyltransferase; Lipoyl-[acp] + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein R07770 ATP + (R)-Lipoate <=> Diphosphate + Lipoyl-AMP R07771 Lipoyl-AMP + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP R07772 cobalt-precorrin 5A acylhydrolase; Cobalt-precorrin 5A + H2O <=> Cobalt-precorrin 5B + Acetaldehyde R07773 S-adenosyl-L-methionine:cobalt-precorrin-5B (C1)-methyltransferase; Cobalt-precorrin 5B + S-Adenosyl-L-methionine <=> Cobalt-precorrin 6 + S-Adenosyl-L-homocysteine R07774 S-adenosyl-L-methionine:cobalt-precorrin-6B C15-methyltransferase (C12-decarboxylating); Cobalt-dihydro-precorrin 6 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 7 + S-Adenosyl-L-homocysteine + CO2 R07775 S-adenosyl-L-methionine:cobalt-precorrin-7 C5-methyltransferase; Cobalt-precorrin 7 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 8 + S-Adenosyl-L-homocysteine R07776 biochanin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Biochanin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pratensein + [Oxidized NADPH---hemoprotein reductase] + H2O R07777 liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration); Liquiritigenin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2,7,4'-Trihydroxyisoflavanone + H2O + [Oxidized NADPH---hemoprotein reductase] R07778 naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration); Naringenin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 2-Hydroxy-2,3-dihydrogenistein + H2O + [Oxidized NADPH---hemoprotein reductase] R07779 bromoxynil,NADPH:oxygen oxidoreductase; Bromoxynil + 2 NADPH + 2 H+ + Oxygen <=> 2,6-Dibromohydroquinone + 2 NADP+ + Hydrogen cyanide + H2O R07780 3,5-dibromo-4-hydroxybenzamide hydro-lyase (nitrile-forming); Bromoxynil + H2O <=> 3,5-Dibromo-4-hydroxybenzamide R07781 2-maleylacetate:NAD+ oxidoreductase; 2-Bromomaleylacetate + NADH + H+ <=> 2-Maleylacetate + NAD+ + Bromide R07782 3,5-Dibromo-4-hydroxybenzamide + H2O <=> 3,5-Dibromo-4-hydroxybenzoate + Ammonia R07783 3,5-Dibromo-4-hydroxybenzoate <=> 2,6-Dibromophenol R07784 2,6-Dibromophenol <=> 2,6-Dibromohydroquinone R07785 2,6-Dibromohydroquinone <=> 2-Bromomaleylacetate R07786 22alpha-hydroxy-campesterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating); 22alpha-Hydroxy-campesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (22R,23R)-22,23-Dihydroxycampesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R07787 22alpha-hydroxy-campest-4-en-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating); (22S)-22-Hydroxycampest-4-en-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one + [Oxidized NADPH---hemoprotein reductase] + H2O R07788 22alpha-Hydroxy-5alpha-campestan-3-one <=> 3-epi-6-Deoxocathasterone R07789 (22R,23R)-22,23-Dihydroxycampesterol <=> (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one R07790 (22R,23R)-22,23-Dihydroxy-campest-4-en-3-one <=> 3-Dehydro-6-deoxoteasterone R07791 22alpha-hydroxy-5alpha-campestan-3-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating); 22alpha-Hydroxy-5alpha-campestan-3-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Dehydro-6-deoxoteasterone + [Oxidized NADPH---hemoprotein reductase] + H2O R07792 3-epi-6-deoxocathasterone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating); 3-epi-6-Deoxocathasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Deoxotyphasterol + [Oxidized NADPH---hemoprotein reductase] + H2O R07793 4-Chloroaniline + Oxygen + 2 H+ <=> 4-Chlorocatechol + Ammonia R07794 2,4-Dichloroaniline + 2 H+ <=> 4-Chloroaniline + Hydrochloric acid R07795 2,3-dihydroxybenzenesulfonate 2,3-dioxygenase; 3-Sulfocatechol + Oxygen + H2O <=> 2-Hydroxymuconate + Sulfite R07796 (E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase; (E)-Cinnamoyl-CoA + Phenyllactate <=> trans-Cinnamate + (R)-Phenyllactyl-CoA R07797 3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase; 3'-Phosphoadenylyl sulfate + Petromyzonol <=> Adenosine 3',5'-bisphosphate + Petromyzonol 24-sulfate R07798 3'-phosphoadenosine 5'-phosphosulfate:5beta-scymnol sulfotransferase; 3'-Phosphoadenylyl sulfate + Scymnol <=> Adenosine 3',5'-bisphosphate + 5beta-Scymnol sulfate R07799 Fluoren-9-one + Oxygen + H+ + NADH <=> 1-Hydro-1,1a-dihydroxy-9-fluorenone + NAD+ R07800 1-Hydro-1,1a-dihydroxy-9-fluorenone + H2O <=> 2,3-Dihydroxy-2'-carboxybiphenyl + 2 H+ R07801 2,3-Dihydroxy-2'-carboxybiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate R07802 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O <=> Phthalate + 2-Hydroxy-2,4-pentadienoate R07803 3-Isochromanone <=> Catechol R07804 (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene <=> 3,4-Dihydroxyfluorene + 2 H+ R07805 keratan sulfate 1,4-beta-D-galactanohydrolase; Keratan sulfate + H2O <=> Keratan sulfate + G01945 R07806 N-acetyl-D-galactosamine 6-sulfate 6-sulfohydrolase; G01945 + H2O <=> G01977 + Sulfate R07807 G01977 + H2O <=> G13073 + D-Galactose R07808 N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase; G13073 + H2O <=> G13074 + Sulfate R07809 G13074 + H2O <=> G01391 + N-Acetyl-D-glucosamine R07810 G13073 + H2O <=> G01391 + N-Acetyl-D-glucosamine 6-sulfate R07811 Heparan sulfate + H2O <=> Heparan sulfate + G13034 R07812 L-iduronate-2-sulfate 2-sulfohydrolase; G13034 + H2O <=> G13035 + Sulfate R07813 G13035 + H2O <=> G13036 + L-Iduronic acid R07814 G13036 + H2O <=> G13037 + Sulfate R07815 acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase; Acetyl-CoA + G13037 <=> CoA + G13038 R07816 G13038 + H2O <=> G13039 + N-Acetyl-D-glucosamine R07817 G13039 + H2O <=> G13040 + Sulfate R07818 G13040 + H2O <=> G09660 + D-Glucuronate R07819 N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase; G09660 + H2O <=> G02632 + Sulfate R07820 Dermatan sulfate + H2O <=> Dermatan sulfate + G13041 R07821 L-iduronate-2-sulfate 2-sulfohydrolase; G13041 + H2O <=> G13042 + Sulfate R07822 G13042 + H2O <=> G12336 + L-Iduronic acid R07823 N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase; G12336 + H2O <=> G13043 + Sulfate R07824 G13043 + H2O <=> DWA-2 + N-Acetylgalactosamine R07825 G12336 + H2O <=> DWA-2 + N-Acetylgalactosamine 4-sulfate R07826 p-coumarate 3-hydroxylase; 4-Coumarate <=> Caffeate R07827 3-chlorocatechol:oxygen 1,2-oxidoreductase (decyclizing); 3-Chlorocatechol + Oxygen <=> 3-Chloro-2-hydroxymuconic semialdehyde R07828 Cyclopropanecarboxylate + CoA + ATP <=> Cyclopropanecarboxyl-CoA + ADP + Orthophosphate R07829 Cyclopropanecarboxyl-CoA <=> Crotonoyl-CoA R07830 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-epi-Isozizaene + Diphosphate R07831 Dihydrophloroglucinol + H2O <=> 3-Hydroxy-5-oxohexanoate R07832 3-hydroxy-5-oxohexanoyl-CoA:acetate CoA-transferase; 3-Hydroxy-5-oxohexanoate + Acetyl-CoA <=> 3-Hydroxy-5-oxohexanoyl-CoA + Acetate R07833 3-Hydroxy-5-oxohexanoyl-CoA + CoA <=> (S)-3-Hydroxybutanoyl-CoA + Acetyl-CoA R07834 1-Hydroxy-1,2-dihydrolycopene <=> Rhodopinal R07835 Terephthalate + H2O <=> Benzoate + Carbonic acid R07836 Thiobenzamide + Oxygen + NADPH + H+ <=> Thiobenzamide S-oxide + NADP+ + H2O R07837 Thiobenzamide S-oxide + NADPH + H+ + Oxygen <=> Thiobenzamide S,S-dioxide + NADP+ + H2O R07838 Thiobenzamide S,S-dioxide <=> Benzonitrile R07839 4-oxalomesaconate keto---enol-isomerase; (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate R07840 carotenoid psi-end group lyase (decyclizing); delta-Carotene <=> epsilon-Carotene R07841 Zeaxanthin <=> Caloxanthin R07842 Caloxanthin <=> Nostoxanthin R07843 Rhodopinal <=> Rhodopinal glucoside R07844 Lycopene <=> (2S,2'S)-Oscillol R07845 (2S,2'S)-Oscillol <=> (2S,2'S)-Oscillol 2,2'-di(alpha-L-fucoside) R07846 Lycopene <=> R.g.-Keto I R07847 R.g.-Keto I <=> R.g.-Keto III R07848 R.g.-Keto I <=> Thiothece-474 R07849 thiothece-474:acceptor oxidoreductase/methyltranferase (chi-ring forming); Thiothece-474 + 2 Acceptor <=> Okenone + 2 Reduced acceptor R07850 alpha-carotene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); alpha-Carotene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> alpha-Cryptoxanthin + [Oxidized NADPH---hemoprotein reductase] + H2O R07851 alpha-cryptoxanthin,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; alpha-Cryptoxanthin + 2 Reduced ferredoxin + H+ + Oxygen <=> Lutein + 2 Oxidized ferredoxin + H2O R07852 gamma-Carotene <=> (2'S)-Deoxymyxol 2'-(2,4-di-O-methyl-alpha-L-fucoside) R07854 2-phenylacetamide hydro-lyase (nitrile-forming); Phenylacetonitrile + H2O <=> 2-Phenylacetamide R07855 phenylacetonitrile aminohydrolase; Phenylacetonitrile + 2 H2O <=> Phenylacetic acid + Ammonia R07856 carotenoid beta-end group lyase (decyclizing); beta-Zeacarotene <=> 7,8-Dihydro-beta-carotene R07857 beta-carotene:acceptor oxidoreductase/methyltranferase (phi-ring forming); beta-Carotene + 2 Acceptor <=> beta-Isorenieratene + 2 Reduced acceptor R07858 beta-isorenieratene:acceptor oxidoreductase/methyltranferase (phi-ring forming); beta-Isorenieratene + 2 Acceptor <=> Isorenieratene + 2 Reduced acceptor R07859 Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid R07860 Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid R07861 (9Z,12Z,15Z)-Octadecatrienoic acid + Reduced acceptor + Oxygen <=> Stearidonic acid + Acceptor + 2 H2O R07862 1'-Hydroxytorulene <=> Deinoxanthin R07863 (9Z,11E,15Z)-(13S)-hydroperoxyoctadeca-9,11,15-trienoate 12,13-hydro-lyase [(9Z,15Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate-forming]; 13(S)-HPOT <=> (9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O R07864 (9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 9(S)-HPOT R07865 9(S)-HPOT <=> 9,10-EOT + H2O R07866 9,10-EOT <=> 10-OPDA R07867 (8E)-9-[(1E,3Z,6Z)-nona-1,3,6-trien-1-yloxy]non-8-enoate synthase; 9(S)-HPOT <=> Colnelenic acid + H2O R07868 9(S)-HPOT <=> 9-Oxononanoic acid + 3,6-Nonadienal R07869 (9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 13(S)-HPOT R07870 13(S)-HPOT <=> 12-Oxo-9(Z)-dodecenoic acid + 3-Hexenal R07871 13(S)-HPOT <=> Etherolenic acid + H2O R07872 12-Oxo-9(Z)-dodecenoic acid <=> Traumatin R07873 caffeoyl-CoA:pelargonidin-3-O-glucoside 6''-O-acyltransferase; Pelargonidin 3-O-glucoside + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA R07874 UDP-alpha-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase; Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonin + UDP R07875 Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + UDP-glucose <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + UDP R07876 caffeoyl-CoA:pelargonidin 3,5-di-beta-D-glucoside 6''-O-acyltransferase; Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + CoA R07877 UDP-alpha-D-glucose:pelargonidin-3-O-glucoside 2''-O-glucosyltransferase; Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonidin 3-O-sophoroside + UDP R07878 UDP-alpha-D-glucose:cyanidin 3-O-glucoside 2''-O-glucosyltransferase; Cyanidin 3-O-glucoside + UDP-glucose <=> Cyanidin 3-O-sophoroside + UDP R07879 UDP-alpha-D-glucose:delphinidin-3-O-glucoside 2''-O-glucosyltransferase; Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin 3-O-sophoroside + UDP R07880 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Pelargonin + p-Coumaroyl-CoA <=> Pelargonidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA R07881 2-Naphthoyl-CoA + H2O <=> 2-Naphthoic acid + CoA R07882 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Cyanidin 3,5-O-diglucoside + p-Coumaroyl-CoA <=> Cyanidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA R07883 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Delphinidin 3,5-diglucoside + p-Coumaroyl-CoA <=> Delphinidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) + CoA R07884 Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Pelargonidin 3-O-3'',6''-O-dimalonylglucoside + CoA R07885 Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=> Cyanidin 3-O-3'',6''-O-dimalonylglucoside + CoA R07886 Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + Malonyl-CoA <=> Delphinidin 3-O-3'',6''-O-dimalonylglucoside + CoA R07887 ATP + (9S,13S,15Z)-12-Oxo-10,11-dihydrophyto-15-enoate + CoA <=> AMP + Diphosphate + OPC8-CoA R07888 OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2 R07889 3-Hydroxy-OPC8-CoA <=> trans-2-Enoyl-OPC8-CoA + H2O R07890 3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+ R07891 OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA R07892 OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2 R07893 3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O R07894 3-Hydroxy-OPC6-CoA + NAD+ <=> 3-Oxo-OPC6-CoA + NADH + H+ R07895 OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA R07896 OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2 R07897 3-Hydroxy-OPC4-CoA <=> trans-2-Enoyl-OPC4-CoA + H2O R07898 3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+ R07899 (+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA R07900 Cyanidin 3-O-rutinoside <=> Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07901 Cyanidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Peonidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07902 (+)-7-Isojasmonic acid CoA + H2O <=> CoA + (+)-7-Isojasmonic acid R07903 Delphinidin 3-O-glucoside + UDP-L-rhamnose <=> Delphinidin 3-O-rutinoside + UDP R07904 Delphinidin 3-O-rutinoside <=> Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07905 Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07906 Petunidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07907 Delphinidin-3-(p-coumaroyl)-rutinoside-5-glucoside <=> Malvidin-3-(p-coumaroyl)-rutinoside-5-glucoside R07908 Cyanidin <=> Cyanidin 5-O-glucoside R07909 Cyanidin 5-O-glucoside <=> Cyanidin 3,5-O-diglucoside R07910 malonyl-CoA:cyanidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase; Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + Malonyl-CoA <=> Malonylshisonin + CoA R07911 UDP-alpha-D-glucose:delphinidin-3-O-beta-D-glucoside 5-O-glucosyltransferase; Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin 3,5-diglucoside + UDP R07912 UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase; Delphinidin 3,5-diglucoside + UDP-glucose <=> Delphinidin 3,5,3'-triglucoside + UDP R07913 UDP-glucose:delphinidin 3'-O-beta-D-glucosyltransferase; Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-glucose <=> Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP R07914 UDP-glucose:delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside 5'-O-glucosyltransferase; Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP-glucose <=> Ternatin C5 + UDP R07915 Ternatin C5 <=> Ternatin A1 R07916 geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase; 2 Geranylgeranyl diphosphate <=> all-trans-Phytoene + 2 Diphosphate R07917 S-adenosyl-L-methionine:xanthosine N7-methyltransferase; S-Adenosyl-L-methionine + Xanthosine <=> S-Adenosyl-L-homocysteine + 7-Methylxanthosine R07918 7-methylxanthosine ribohydrolase; 7-Methylxanthosine + H2O <=> 7-Methylxanthine + D-Ribose R07919 S-adenosyl-L-methionine:7-methylxanthine N3-methyltransferase; S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + Theobromine R07920 S-adenosyl-L-methionine:3,7-dimethylxanthine N1-methyltransferase; S-Adenosyl-L-methionine + Theobromine <=> S-Adenosyl-L-homocysteine + Caffeine R07921 S-adenosyl-L-methionine:1,7-dimethylxanthine N3-methyltransferase; S-Adenosyl-L-methionine + 1,7-Dimethylxanthine <=> S-Adenosyl-L-homocysteine + Caffeine R07922 S-Adenosyl-L-methionine + 7-Methylxanthine <=> S-Adenosyl-L-homocysteine + 1,7-Dimethylxanthine R07923 UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase; Delphinidin 3-glucoside 5-caffoyl-glucoside + UDP-glucose <=> Albireodelphin + UDP R07924 Albireodelphin <=> Gentiodelphin R07925 Delphinidin 3,5,3'-triglucoside <=> Gentiodelphin R07926 caffeoyl-CoA:delphinidin-3-O-glucoside 6''-O-acyltransferase; Delphinidin 3-O-glucoside + Caffeoyl-CoA <=> Delphinidin 3-O-(6-caffeoyl-beta-D-glucoside) + CoA R07927 4-hydroxycinnamoyl-CoA:pelargonidin-3-O-glucoside 6''-O-acyltransferase; Pelargonidin 3-O-glucoside + p-Coumaroyl-CoA <=> Pelargonidin 3-(6-p-coumaroyl)glucoside + CoA R07928 caffeoyl-CoA:cyanidin-3-O-glucoside 6''-O-acyltransferase; Cyanidin 3-O-glucoside + Caffeoyl-CoA <=> Cyanidin 3-(6-p-caffeoyl)glucoside + CoA R07929 4-hydroxycinnamoyl-CoA:delphinidin-3-O-glucoside 6''-O-acyltransferase; Delphinidin 3-O-glucoside + p-Coumaroyl-CoA <=> Delphinidin 3-(6-p-coumaroyl)glucoside + CoA R07930 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Pelargonin + Caffeoyl-CoA <=> Pelargonidin 3-glucoside 5-caffeoylglucoside + CoA R07931 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Cyanidin 3,5-O-diglucoside + Caffeoyl-CoA <=> Cyanidin 3-glucoside 5-caffeoylglucoside + CoA R07932 UDP-alpha-D-glucuronate:cyanidin-3-O-(6-O-malonyl-beta-D-glucoside) 2-O-beta-D-glucuronosyltransferase; Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + UDP-glucuronate <=> Cyanidin-3-O-(6''-O-malonyl-2''-O-glucuronyl)glucoside + UDP R07933 alpha-linolenoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); (9Z,12Z,15Z)-Octadecatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z)-Octadecatetraenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R07934 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA:oxygen 2-oxidoreductase; (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + Hydrogen peroxide R07935 (3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA hydro-lyase; (3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O R07936 (3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA:NAD+ oxidoreductase; (3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA + NADH + H+ R07937 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA:acetyl-CoA C-acyltransferase; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA R07938 malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase; Delphinidin 3-O-glucoside + Malonyl-CoA <=> Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + CoA R07939 caffeine:oxygen oxidoreductase (N3-demethylating); Caffeine + NADPH + Oxygen + H+ <=> 1,7-Dimethylxanthine + NADP+ + Formaldehyde + H2O R07940 1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil R07941 5-Acetylamino-6-formylamino-3-methyluracil <=> 5-Acetylamino-6-amino-3-methyluracil R07942 1-methylxanthine:oxygen oxidoreductase; 1-Methylxanthine + H2O + Oxygen <=> 1-Methyluric acid + Hydrogen peroxide R07943 1,7-Dimethylxanthine <=> 1-Methylxanthine R07944 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase; Delphinidin 3,5-diglucoside + Caffeoyl-CoA <=> Delphinidin 3-glucoside 5-caffoyl-glucoside + CoA R07945 1,7-Dimethylxanthine <=> 1,7-Dimethyluric acid R07946 (R)-Nicotine + Acceptor + H2O <=> (R)-6-Hydroxynicotine + Reduced acceptor R07947 2,6-Dihydroxypseudooxynicotine <=> 2,6-Dihydroxy-N-methylmyosmine + H2O R07948 2 2,3,6-Trihydroxypyridine + 2 Oxygen <=> Blue pigment + 2 Hydrogen peroxide R07949 2,3,6-Trihydroxypyridine + Oxygen + H+ <=> Maleamate + 2 H+ + CO2 R07950 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA:oxygen 2-oxidoreductase; (6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + Oxygen <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + Hydrogen peroxide R07951 (3R,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA hydro-lyase; (3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + H2O R07952 (3R,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA:NAD+ oxidoreductase; (3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + NADH + H+ R07953 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA:acetyl-CoA C-acyltransferase; (4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA R07954 caffeine:oxygen oxidoreductase (N3-demethylating); Caffeine + NADH + H+ + Oxygen <=> 1,7-Dimethylxanthine + NAD+ + Formaldehyde + H2O R07955 caffeine:oxygen oxidoreductase (N1-demethylating); Caffeine + NADH + H+ + Oxygen <=> Theobromine + NAD+ + Formaldehyde + H2O R07956 caffeine:oxygen oxidoreductase (N1-demethylating); Caffeine + NADPH + H+ + Oxygen <=> Theobromine + NADP+ + Formaldehyde + H2O R07957 paraxanthine:oxygen oxidoreductase (N1-demethylating); 1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O R07958 paraxanthine:oxygen oxidoreductase (N1-demethylating); 1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O R07959 1,7-Dimethylxanthine + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O R07960 1,7-Dimethylxanthine + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O R07961 theobromine:oxygen oxidoreductase (N3-demethylating); Theobromine + NADH + H+ + Oxygen <=> 7-Methylxanthine + NAD+ + Formaldehyde + H2O R07962 theobromine:oxygen oxidoreductase (N3-demethylating); Theobromine + NADPH + H+ + Oxygen <=> 7-Methylxanthine + NADP+ + Formaldehyde + H2O R07963 Theobromine + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O R07964 Theobromine + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O R07965 7-methylxanthine:oxygen oxidoreductase (demethylating); 7-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O R07966 7-methylxanthine:oxygen oxidoreductase (demethylating); 7-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O R07967 3-methylxanthine:oxygen oxidoreductase (N3-demethylating); 3-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O R07968 3-methylxanthine:oxygen oxidoreductase (N3-demethylating); 3-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O R07969 1-methylxanthine:oxygen oxidoreductase (N1-demethylating); 1-Methylxanthine + NADH + H+ + Oxygen <=> Xanthine + NAD+ + Formaldehyde + H2O R07970 1-methylxanthine:oxygen oxidoreductase (N1-demethylating); 1-Methylxanthine + NADPH + H+ + Oxygen <=> Xanthine + NADP+ + Formaldehyde + H2O R07971 Caffeine + NADH + H+ + Oxygen <=> Theophylline + NAD+ + Formaldehyde + H2O R07972 Caffeine + NADPH + H+ + Oxygen <=> Theophylline + NADP+ + Formaldehyde + H2O R07973 theophylline:oxygen oxidoreductase (N1-demethylating); Theophylline + NADH + H+ + Oxygen <=> 3-Methylxanthine + NAD+ + Formaldehyde + H2O R07974 theophylline:oxygen oxidoreductase (N1-demethylating); Theophylline + NADPH + H+ + Oxygen <=> 3-Methylxanthine + NADP+ + Formaldehyde + H2O R07975 theophylline:oxygen oxidoreductase (N3-demethylating); Theophylline + NADH + H+ + Oxygen <=> 1-Methylxanthine + NAD+ + Formaldehyde + H2O R07976 theophylline:oxygen oxidoreductase (N3-demethylating); Theophylline + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O R07977 1,7-dimethylxanthine:oxygen oxidoreductase; 1,7-Dimethylxanthine + Oxygen + H2O <=> 1,7-Dimethyluric acid + Hydrogen peroxide R07978 3,7-dimethylxanthine:oxygen oxidoreductase; Theobromine + H2O + Oxygen <=> 3,7-Dimethyluric acid + Hydrogen peroxide R07979 7-methylxanthine:oxygen oxidoreductase; 7-Methylxanthine + Oxygen + H2O <=> 7-Methyluric acid + Hydrogen peroxide R07980 caffeine:ubiquinone oxidoreductase; Caffeine + Ubiquinone + H2O <=> 1,3,7-Trimethyluric acid + Ubiquinol R07981 1,3,7-Trimethyluric acid + Oxygen + 2 H2O <=> 3,6,8-Trimethylallantoin + CO2 + Hydrogen peroxide R07982 3,6,8-Trimethylallantoin + 2 H2O <=> N,N'-Dimethylurea + N-Methylurea + Glyoxylate R07983 2,6-Dihydroxynicotinate + H2O + Oxygen <=> Maleamate + CO2 + Formate R07984 6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase; 6-Oxo-1,4,5,6-tetrahydronicotinate + 2 H2O <=> 2-Formylglutarate + Ammonia R07985 (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase; 2-Formylglutarate + NADH + H+ <=> (S)-2-(Hydroxymethyl)glutarate + NAD+ R07986 (S)-2-(Hydroxymethyl)glutarate <=> 2-Methyleneglutarate + H2O R07987 malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing); Cinnamoyl-CoA + 3 Malonyl-CoA <=> Pinocembrin chalcone + 4 CoA + 3 CO2 R07988 malonyl-CoA:caffeoyl-CoA malonyltransferase (cyclizing); Caffeoyl-CoA + 3 Malonyl-CoA <=> Eriodictyol chalcone + 4 CoA + 3 CO2 R07989 malonyl-CoA:feruloyl-CoA malonyltransferase (cyclizing); Feruloyl-CoA + 3 Malonyl-CoA <=> Homoeriodictyol chalcone + 4 CoA + 3 CO2 R07990 flavanone lyase (decyclizing); Pinocembrin chalcone <=> Pinocembrin R07991 Eriodictyol chalcone <=> Eriodictyol R07992 Homoeriodictyol chalcone <=> Homoeriodictyol R07993 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Pinocembrin + 2-Oxoglutarate + Oxygen <=> Pinobanksin + Succinate + CO2 R07994 Isoliquiritigenin <=> Butein R07995 flavanone lyase (decyclizing); Butein <=> Butin R07996 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Liquiritigenin + 2-Oxoglutarate + Oxygen <=> Garbanzol + Succinate + CO2 R07997 flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); Butin + 2-Oxoglutarate + Oxygen <=> Fustin + Succinate + CO2 R07998 5-deoxyleucopelargonidin:NADP+ 4-oxidoreductase; 5-Deoxyleucopelargonidin + NADP+ <=> Garbanzol + NADPH + H+ R07999 5-deoxyleucocyanidin:NADP+ 4-oxidoreductase; Fisetinidol-4beta-ol + NADP+ <=> Fustin + NADPH + H+ R08000 5-Deoxyleucopelargonidin <=> Garbanzol R08001 Fisetinidol-4beta-ol <=> Fustin R08002 liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Butin + [Oxidized NADPH---hemoprotein reductase] + H2O R08003 Naringenin chalcone + Dimethylallyl diphosphate <=> Desmethylxanthohumol + Diphosphate R08004 S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase; Desmethylxanthohumol + S-Adenosyl-L-methionine <=> Xanthohumol + S-Adenosyl-L-homocysteine R08005 2',3,4,4',6'-pentahydroxychalcone:oxygen oxidoreductase; Eriodictyol chalcone + Oxygen <=> Bracteatin + H2O R08006 UDP-alpha-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucosyltransferase; Naringenin chalcone + UDP-glucose <=> 2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + UDP R08007 UDP-alpha-D-glucose:2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucosyltransferase; Eriodictyol chalcone + UDP-glucose <=> 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + UDP R08008 2',4,4',6'-tetrahydroxychalcone 4'-O-glucoside:oxygen oxidoreductase; 2',4,4',6'-Tetrahydroxychalcone 4'-O-glucoside + Oxygen <=> Aureusidin 6-O-glucoside + H2O R08009 2',3,4,4',6'-peptahydroxychalcone 4'-O-glucoside:oxygen oxidoreductase; 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> Bracteatin 6-O-glucoside + H2O R08010 2',3,4,4',6'-peptahydroxychalcone 4'-O-glucoside:oxygen oxidoreductase; 2 2',3,4,4',6'-Peptahydroxychalcone 4'-O-glucoside + Oxygen <=> 2 Aureusidin 6-O-glucoside + 2 H2O R08011 Aureusidin <=> Bracteatin R08012 Eriodictyol <=> Homoeriodictyol R08013 Naringenin chalcone + UDP-glucose <=> Phlorizin chalcone + UDP R08014 Trinitrotoluene + 2 NADPH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NADP+ + H2O R08015 4-Hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H+ <=> 2,4-Dihydroxylamino-6-nitrotoluene + 2 NADP+ + H2O R08016 2,4-Dihydroxylamino-6-nitrotoluene + NADPH + H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + NADP+ + H2O R08017 Trinitrotoluene + 2 NADH + 2 H+ <=> 4-Hydroxylamino-2,6-dinitrotoluene + 2 NAD+ + H2O R08018 4-Hydroxylamino-2,6-dinitrotoluene + NADH + H+ <=> 4-Amino-2,6-dinitrotoluene + NAD+ + H2O R08019 4-Hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-Amino-2,6-dinitrotoluene + NADP+ + H2O R08020 4 4-Hydroxylamino-2,6-dinitrotoluene + Oxygen <=> 2 2,2',6,6'-Tetranitro-4,4'-azoxytoluene + 4 H2O R08021 UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase; UDP-glucose + Hesperetin <=> UDP + Hesperetin 7-O-glucoside R08022 UDP-L-rhamnose:hesperetin-7-O-glucoside 2''-O-alpha-L-rhamnosyltransferase; Hesperetin 7-O-glucoside + UDP-L-rhamnose <=> Neohesperidin + UDP R08023 4-Coumarate <=> Naringin chalcone R08024 Naringin chalcone <=> Naringin R08026 Naringenin <=> Hesperetin R08027 2,4-Diamino-6-nitrotoluene <=> 2,4,6-Triaminotoluene R08028 Pinobanksin <=> Pinobanksin 3-O-acetate R08029 Pinocembrin <=> Pinostrobin R08030 2,6-Diamino-4-nitrotoluene <=> 2,4,6-Triaminotoluene R08031 Eriodictyol chalcone <=> Homoeriodictyol chalcone R08032 garbanzol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating); Garbanzol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fustin + [Oxidized NADPH---hemoprotein reductase] + H2O R08033 2-Amino-4,6-dinitrotoluene <=> 2-Amino-4-nitrotoluene R08034 2,4-Diamino-6-nitrotoluene <=> 2,4-Diamino-6-hydroxylaminotoluene R08035 2,4-Diamino-6-hydroxylaminotoluene <=> 2,4,6-Triaminotoluene R08036 acetyl-CoA:2,4-diamino-6-nitrotoluene N-acetyltransferase; 2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA R08037 2 4-Hydroxylamino-2,6-dinitrotoluene + 2 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 2,4',6,6'-Tetranitro-2',4-azoxytoluene + 4 H2O R08038 4 2-Hydroxylamino-4,6-dinitrotoluene + Oxygen <=> 2 4,4',6,6'-Tetranitro-2,2'-azoxytoluene + 4 H2O R08040 2,4,6-Triaminotoluene <=> 2,4,6-Trihydroxytoluene R08041 2,4,6-Trihydroxytoluene <=> 4-Cresol R08042 Trinitrotoluene + 2 NADH + 2 H+ <=> 2-Hydroxylamino-4,6-dinitrotoluene + 2 NAD+ + H2O R08043 2-Hydroxylamino-4,6-dinitrotoluene + NADH + H+ <=> 2-Amino-4,6-dinitrotoluene + NAD+ + H2O R08044 2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,6-Diamino-4-nitrotoluene + 3 NAD+ + 2 H2O R08045 2-Amino-4,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O R08046 4-Amino-2,6-dinitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diamino-6-nitrotoluene + 3 NAD+ + 2 H2O R08047 4-Amino-2,6-dinitrotoluene + 2 NADH + 2 H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + 2 NAD+ + H2O R08048 2,4-Dihydroxylamino-6-nitrotoluene <=> 2-Amino-5-hydroxyl-4-hydroxylamino-6-nitrotoluene R08049 4-Amino-2-hydroxylamino-6-nitrotoluene <=> 2,4-Diamino-6-nitrotoluene R08050 Ectoine + 2-Oxoglutarate + Oxygen <=> 5-Hydroxyectoine + Succinate + CO2 R08051 2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase; dimethylallyl-diphosphate:ATP dimethylallyltransferase; Dimethylallyl diphosphate + ATP <=> Isopentenyladenosine-5'-triphosphate + Diphosphate R08052 2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase; dimethylallyl-diphosphate:ADP dimethylallyltransferase; Dimethylallyl diphosphate + ADP <=> Isopentenyladenosine-5'-diphosphate + Diphosphate R08053 isopentenyladenosine-5'-triphosphate,NADPH---hemoprotein reductase:oxygen oxidoreductase (trans-zeatin-riboside-triphosphate-forming); Isopentenyladenosine-5'-triphosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside triphosphate + [Oxidized NADPH---hemoprotein reductase] + H2O R08054 isopentenyladenosine-5'-diphosphate,NADPH---hemoprotein reductase:oxygen oxidoreductase (trans-zeatin-riboside-diphosphate-forming); Isopentenyladenosine-5'-diphosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside diphosphate + [Oxidized NADPH---hemoprotein reductase] + H2O R08055 isopentenyladenosine-5'-monophosphate,NADPH---hemoprotein reductase:oxygen oxidoreductase (trans-zeatin-riboside-monophosphate-forming); N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside monophosphate + [Oxidized NADPH---hemoprotein reductase] + H2O R08056 D-glucarate hydro-lyase; D-Glucarate <=> 2-Dehydro-3-deoxy-D-glucarate + H2O R08057 GTP:GTP guanylyltransferase; 2 GTP <=> 3',5'-Cyclic diGMP + 2 Diphosphate R08058 5,6,7,8-tetrahydromethanopterin hydro-lyase (formaldehyde-adding, 5,10-methylenetetrahydromethanopterin-forming); 5,6,7,8-Tetrahydromethanopterin + Formaldehyde <=> 5,10-Methylenetetrahydromethanopterin + H2O R08059 5,10-Methylenetetrahydromethanopterin + NADP+ <=> 5,10-Methenyltetrahydromethanopterin + NADPH R08060 Formylmethanofuran + H2O <=> Formate + Methanofuran R08061 Isopentenyladenosine-5'-triphosphate + H2O <=> Isopentenyladenosine-5'-diphosphate + Orthophosphate R08062 Isopentenyladenosine-5'-diphosphate + H2O <=> N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + Orthophosphate R08063 trans-Zeatin riboside triphosphate + H2O <=> trans-Zeatin riboside diphosphate + Orthophosphate R08064 trans-Zeatin riboside diphosphate + H2O <=> trans-Zeatin riboside monophosphate + Orthophosphate R08065 trans-Zeatin riboside monophosphate <=> Dihydrozeatin riboside monophosphate R08066 isopentenyladenosine,NADPH---hemoprotein reductase:oxygen oxidoreductase (trans-zeatin-riboside-forming); Isopentenyl adenosine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> trans-Zeatin riboside + [Oxidized NADPH---hemoprotein reductase] + H2O R08067 trans-Zeatin riboside <=> Dihydrozeatin riboside R08068 isopentenyladenine,NADPH---hemoprotein reductase:oxygen oxidoreductase (trans-zeatin-forming); N6-(Delta2-Isopentenyl)-adenine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Zeatin + [Oxidized NADPH---hemoprotein reductase] + H2O R08069 N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate + H2O <=> Isopentenyl adenosine + Orthophosphate R08070 trans-Zeatin riboside monophosphate + H2O <=> trans-Zeatin riboside + Orthophosphate R08071 Dihydrozeatin riboside monophosphate + H2O <=> Dihydrozeatin riboside + Orthophosphate R08072 Isopentenyl adenosine + H2O <=> N6-(Delta2-Isopentenyl)-adenine + D-Ribose R08073 trans-Zeatin riboside + H2O <=> Zeatin + D-Ribose R08074 Dihydrozeatin riboside + H2O <=> Dihydrozeatin + D-Ribose R08075 Zeatin + UDP-glucose <=> trans-Zeatin-7-beta-D-glucoside + UDP R08076 Dihydrozeatin + UDP-glucose <=> Dihydrozeatin-O-glucoside + UDP R08077 tRNA containing 6-isopentenyladenosine <=> cis-Prenyl-tRNA R08078 cis-Prenyl-tRNA <=> cis-Zeatin riboside monophosphate R08079 cis-Zeatin riboside monophosphate + H2O <=> cis-Zeatin riboside + Orthophosphate R08080 cis-Zeatin riboside + H2O <=> cis-Zeatin + D-Ribose R08081 flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Pinocembrin + 2-Oxoglutarate + Oxygen <=> Chrysin + Succinate + CO2 + H2O R08082 dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase; Pinobanksin + 2-Oxoglutarate + Oxygen <=> Galangin + Succinate + CO2 + H2O R08083 Nerol + NADP+ <=> cis-Citral + NADPH + H+ R08084 beta-Citronellol + NADP+ <=> (R)-(+)-Citronellal + NADPH + H+ R08085 (-)-Citronellol + NADP+ <=> (S)-(-)-Citronellal + NADPH + H+ R08086 geranial:NAD+ oxidoreductase; Geranial + NAD+ + H2O <=> Geranic acid + NADH + H+ R08087 (R)-(+)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+ R08088 citronellyl-CoA ligase; Citronellate + CoA + ATP <=> Citronellyl-CoA + AMP + Diphosphate R08089 Citronellyl-CoA + Acceptor <=> Geranoyl-CoA + Reduced acceptor R08090 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming); 3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 7-Methyl-3-oxo-6-octenoyl-CoA + Acetate R08091 7-methyl-3-oxo-6-octenoyl-CoA:acetyl-CoA C-acyltransferase; 7-Methyl-3-oxo-6-octenoyl-CoA + CoA <=> 5-Methylhex-4-enoyl-CoA + Acetyl-CoA R08092 5-Methylhex-4-enoyl-CoA + FAD <=> (2E)-5-Methylhexa-2,4-dienoyl-CoA + FADH2 R08093 3-hydroxy-5-methylhex-4-enoyl-CoA hydro-lyase; (2E)-5-Methylhexa-2,4-dienoyl-CoA + H2O <=> 3-Hydroxy-5-methylhex-4-enoyl-CoA R08094 3-hydroxy-5-methylhex-4-enoyl-CoA:NAD+ oxidoreductase; 3-Hydroxy-5-methylhex-4-enoyl-CoA + NAD+ <=> 5-Methyl-3-oxo-4-hexenoyl-CoA + NADH + H+ R08095 3-methylcrotonyl-CoA:acetyl-CoA C-acyltransferase; 5-Methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-Methylcrotonyl-CoA + Acetyl-CoA R08096 (S)-(-)-Citronellal + NAD+ + H2O <=> Citronellate + NADH + H+ R08097 Geranic acid + CoA <=> trans-Geranyl-CoA + H2O R08098 trans-Geranyl-CoA <=> Geranoyl-CoA R08099 cis-Citral <=> Geranial R08100 2-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); 2-Fluorobenzoate + NADH + H+ + Oxygen <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ R08101 2-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); 2-Fluorobenzoate + NADH + H+ + Oxygen <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ R08102 Astaxanthin <=> Astaxanthin diester R08103 Fluorobenzene + NADH + Oxygen + H+ <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ R08104 Fluorobenzene + NADH + H+ + Oxygen <=> 1-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ R08105 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ <=> 4-Fluorocatechol + NADH + H+ R08106 1-Fluorocyclohexadiene-cis,cis-1,2-diol <=> Catechol + Hydrofluoric acid R08107 Phosphatidylethanolamine + G00149 <=> 1,2-Diacyl-sn-glycerol + G13044 R08108 3-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); 3-Fluorobenzoate + NADH + Oxygen + H+ <=> 3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ R08109 3-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); 3-Fluorobenzoate + NADH + H+ + Oxygen <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ R08110 4-fluorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating); 4-Fluorobenzoate + NADH + H+ + Oxygen <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ R08111 3-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating); 3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 3-Fluorocatechol + NADH + CO2 + H+ R08112 5-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating); 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+ R08113 4-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating); 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+ R08114 3-fluorocatechol:oxygen 1,2-oxidoreductase; 3-Fluorocatechol + Oxygen <=> 2-Fluoro-cis,cis-muconate R08115 4-fluorocatechol:oxygen 1,2-oxidoreductase; 4-Fluorocatechol + Oxygen <=> 3-Fluoro-cis,cis-muconate R08116 4-fluoromuconolactone lyase (decyclizing); 3-Fluoro-cis,cis-muconate <=> 4-Fluoromuconolactone R08117 4-fluorobenzoate:CoA ligase; 4-Fluorobenzoate + CoA + ATP <=> 4-Fluorobenzoyl-CoA + AMP + Diphosphate R08118 4-fluorobenzoyl CoA fluorohydrolase; 4-Fluorobenzoyl-CoA + H2O <=> 4-Hydroxybenzoyl-CoA + Hydrofluoric acid R08119 5-fluoromuconolactone lyase (decyclizing); 2-Fluoro-cis,cis-muconate <=> 5-Fluoromuconolactone R08120 5-fluoromuconolactone lactonohydrolase; 5-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid R08121 4-fluoromuconolactone lactonohydrolase; 4-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid R08122 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> Catechol R08123 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> 3-Fluorocatechol R08124 ATP:D-fructosyl-L-lysine 6-phosphotransferase; Fructoselysine + ATP <=> Fructoselysine 6-phosphate + ADP R08125 Fructoselysine 6-phosphate + H2O <=> L-Lysine + D-Glucose 6-phosphate R08126 Isovitexin <=> Isovitexin 2''-O-arabinoside R08127 beta-D-glucuronoside glucuronosohydrolase; Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + H2O <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + D-Glucuronate R08128 Kaempferol-3-O-galactoside + UDP-glucose <=> Kaempferol 3-O-beta-D-glucosylgalactoside + UDP R08129 Naringenin <=> 8-C-Glucosylnaringenin R08130 8-C-Glucosylnaringenin <=> Vitexin R08132 7-Dehydrocholesterol <=> 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione R08133 2,22,25-Trideoxyecdysone <=> 2,22-Dideoxyecdysone R08134 2,22-Dideoxyecdysone <=> 2-Deoxyecdysone R08135 2-Deoxyecdysone <=> Ecdysone R08136 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22-Dideoxy-3-dehydroecdysone R08137 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione <=> 2,22,25-Trideoxyecdysone R08138 2,22-Dideoxy-3-dehydroecdysone <=> 3-Dehydro-2-deoxyecdysone R08139 3-Dehydro-2-deoxyecdysone <=> 3-Dehydroecdysone R08140 3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+ R08141 3-Dehydroecdysone + NADH + H+ <=> Ecdysone + NAD+ R08142 Ecdysone <=> 26-Hydroxyecdysone R08143 20-Hydroxyecdysone <=> 20,26-Dihydroxyecdysone R08144 farnesyl-diphosphate phosphohydrolase; trans,trans-Farnesyl diphosphate + 2 H2O <=> (2E,6E)-Farnesol + 2 Orthophosphate R08145 Farnesol <=> Farnesal R08146 farnesal:NAD+ oxidoreductase; 2-trans,6-trans-Farnesal + NAD+ + H2O <=> Farnesoic acid + NADH + H+ R08147 S-adenosyl-L-methionine:(2E,6E)-farnesoate O-methyltransferase; Farnesoic acid + S-Adenosyl-L-methionine <=> Methyl farnesoate + S-Adenosyl-L-homocysteine R08148 methyl (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Methyl farnesoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Juvenile hormone III + [Oxidized NADPH---hemoprotein reductase] + H2O R08149 juvenile hormone III acylhydrolase; Juvenile hormone III + H2O <=> Juvenile hormone III acid + Methanol R08150 (10S)-Juvenile hormone III diol + H2O <=> (10S)-Juvenile hormone III acid diol + Methanol R08151 S-adenosyl-L-methionine:juvenile hormone III acid O-methyltransferase; Juvenile hormone III acid + S-Adenosyl-L-methionine <=> Juvenile hormone III + S-Adenosyl-L-homocysteine R08152 Juvenile hormone III acid + H2O <=> (10S)-Juvenile hormone III acid diol R08153 Juvenile hormone III + H2O <=> (10S)-Juvenile hormone III diol R08154 (10S)-Juvenile hormone III diol + ATP <=> (10S)-Juvenile hormone III diol phosphate + ADP R08155 Juvenile hormone III <=> 12-trans-Hydroxy juvenile hormone III R08157 octanoyl-[acyl-carrier protein] hydrolase; Octanoyl-[acp] + H2O <=> Acyl-carrier protein + Octanoic acid R08158 decanoyl-[acyl-carrier protein] hydrolase; Decanoyl-[acp] + H2O <=> Acyl-carrier protein + Decanoic acid R08159 tetradecanoyl-[acyl-carrier protein] hydrolase; Tetradecanoyl-[acp] + H2O <=> Acyl-carrier protein + Tetradecanoic acid R08160 L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08161 hexadecanoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating); Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Hexadecenoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R08162 hexadecenoyl-[acyl-carrier protein] hydrolase; Hexadecenoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + (9Z)-Hexadecenoic acid R08163 octadecanoyl-[acyl-carrier protein] hydrolase; Octadecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Octadecanoic acid R08164 UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase; Indolylmethylthiohydroximate + UDP-glucose <=> Indolylmethyl-desulfoglucosinolate + UDP R08165 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Isochorismate + 2-Oxoglutarate <=> 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2 R08166 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate <=> (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + Pyruvate R08167 3'-phosphoadenylyl-sulfate:indolylmethyl-desulfoglucosinolate sulfotransferase; Indolylmethyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucobrassicin + Adenosine 3',5'-bisphosphate R08168 indole-3-acetaldehyde-oxime,NADPH:oxidoreductase; Indole-3-acetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + NADP+ + 2 H2O R08170 S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> Indolylmethylthiohydroximate + Pyruvate + Ammonia R08171 benzoyl-CoA:3'-N-debenzoyltaxol 3'-N-benzoyltransferase; 3'-N-Debenzoyltaxol + Benzoyl-CoA <=> Paclitaxel + CoA R08172 (3R)-3-amino-3-phenylpropanoyl-CoA:baccatin III C-13 O-((3R)-3-amino-3-phenylpropanoyl)transferase; Baccatin III + beta-Phenylalanoyl-CoA <=> 3'-N-Debenzoyl-2'-deoxytaxol + CoA R08173 13-O-beta-phenylalanoylbaccatin III 2'-hydroxylase; 3'-N-Debenzoyl-2'-deoxytaxol + Reduced acceptor + Oxygen <=> 3'-N-Debenzoyltaxol + Acceptor + H2O R08174 stearoyl-CoA hydrolase; Stearoyl-CoA + H2O <=> CoA + Octadecanoic acid R08175 icosanoyl-CoA hydrolase; Eicosanoyl-CoA + H2O <=> CoA + Icosanoic acid R08176 oleoyl-CoA hydrolase; Oleoyl-CoA + H2O <=> CoA + (9Z)-Octadecenoic acid R08177 linoleoyl-CoA hydrolase; Linoleoyl-CoA + H2O <=> CoA + Linoleate R08178 (9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid R08179 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA hydrolase; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + H2O <=> CoA + (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid R08180 (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid R08181 gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid R08182 8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + Dihomo-gamma-linolenate R08183 Arachidonyl-CoA + H2O <=> CoA + Arachidonate R08184 Docosanoyl-CoA + H2O <=> CoA + Docosanoic acid R08185 Tetracosanoyl-CoA + H2O <=> CoA + Tetracosanoic acid R08186 Icosenoyl-CoA + H2O <=> CoA + Icosenoic acid R08187 Docosenoyl-CoA + H2O <=> CoA + Erucic acid R08188 Tetracosenoyl-CoA + H2O <=> CoA + (15Z)-Tetracosenoic acid R08189 (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoyl-CoA + H2O <=> CoA + (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid R08190 (11Z,14Z)-Icosadienoyl-CoA + H2O <=> CoA + Icosadienoic acid R08191 (7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H2O <=> CoA + Adrenic acid R08192 (11Z,14Z,17Z)-Icosatrienoyl-CoA + H2O <=> CoA + Icosatrienoic acid R08193 N-acetyl-D-glucosamine 1-phosphate 1,6-phosphomutase; N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-alpha-D-glucosamine 1-phosphate R08194 1,5-anhydro-D-mannitol:NADP+ oxidoreductase; 1,5-Anhydro-D-mannitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ R08195 D-threonine acetaldehyde-lyase (glycine-forming); D-Threonine <=> Glycine + Acetaldehyde R08196 D-allothreonine acetaldehyde-lyase (glycine-forming); D-Allothreonine <=> Glycine + Acetaldehyde R08197 L-arginine:pyruvate aminotransferase; L-Arginine + Pyruvate <=> 5-Guanidino-2-oxopentanoate + L-Alanine R08198 2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+ R08199 dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming); Dimethylallyl diphosphate <=> Isoprene + Diphosphate R08200 3-Phosphonopyruvate + H2O <=> Pyruvate + Orthophosphate R08201 ATP + 2-Oxoglutarate + HCO3- <=> ADP + Orthophosphate + Oxalosuccinate R08203 chlorophyllide-a,NADPH:oxygen 7(1)-oxidoreductase (hydroxylating); Chlorophyllide + Oxygen + NADPH + H+ <=> 7(1)-Hydroxychlorophyllide a + H2O + NADP+ R08204 7(1)-hydroxychlorophyllide-a,NADPH:oxygen 7(1)-oxidoreductase; 7(1)-Hydroxychlorophyllide a + Oxygen + NADPH + H+ <=> Chlorophyllide b + 2 H2O + NADP+ R08205 Androstenedione + NADPH + H+ + Oxygen <=> Testololactone + NADP+ + H2O R08206 17alpha-Hydroxyprogesterone + NADPH + H+ + Oxygen <=> Androstenedione + Acetate + NADP+ + H2O R08207 (+)-marmesin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Marmesin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Psoralen + [Oxidized NADPH---hemoprotein reductase] + Acetone + 2 H2O R08208 tetrahydrobiopterin:NADP+ oxidoreductase (6-pyruvoyltetrahydropterin-forming); Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+ R08210 dimethylallyl diphosphate:ferredoxin oxidoreductase; Dimethylallyl diphosphate + 2 Oxidized ferredoxin + H2O <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + 2 Reduced ferredoxin + 2 H+ R08211 betaine aldehyde:oxygen oxidoreductase; Betaine aldehyde + Oxygen + H2O <=> Betaine + Hydrogen peroxide R08212 choline oxidase; Choline + 2 Oxygen + H2O <=> Betaine + 2 Hydrogen peroxide R08213 2-Oxoglutarate + Acetyl-CoA <=> trans-Homoaconitate + CoA R08214 (-)-threo-iso(homo)2-citrate:NAD+ oxidoreductase (decarboxylating); (-)-threo-Iso(homo)2-citrate + NAD+ <=> 2-Oxopimelate + CO2 + NADH + H+ R08215 (-)-threo-iso(homo)3-citrate:NAD+ oxidoreductase (decarboxylating); (-)-threo-Iso(homo)3-citrate + NAD+ <=> 2-Oxosuberate + CO2 + NADH + H+ R08217 ATP:7-mercaptoheptanoylthreonine 3-phosphotransferase; 7-Mercaptoheptanoylthreonine + ATP <=> Coenzyme B + ADP R08218 L-serine:tRNASec ligase (AMP-forming); ATP + L-Serine + tRNA(Sec) <=> AMP + Diphosphate + L-Seryl-tRNA(Sec) R08219 selenophosphate:L-seryl-tRNASec selenium transferase; L-Seryl-tRNA(Sec) + Selenophosphoric acid <=> L-Selenocysteinyl-tRNA(Sec) + Orthophosphate R08220 capecitabine hydrolase; Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2 R08221 5'-deoxy-5-fluorocytidine aminohydrolase; 5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia R08222 5'-deoxy-5-fluorouridine:phosphate deoxy-alpha-D-ribosyltransferase; 5'-Deoxy-5-fluorouridine + Orthophosphate <=> 5-FU + 5-Deoxyribose-1-phosphate R08223 L-seryl-tRNA(Sec) kinase; L-Seryl-tRNA(Sec) + ATP <=> O-Phosphoseryl-tRNA(Sec) + ADP R08224 selenophosphate:O-phospho-L-seryl-tRNA(Sec) selenium transferase; O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O <=> L-Selenocysteinyl-tRNA(Sec) + 2 Orthophosphate R08225 Tegafur + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-FU + Succinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O R08226 5,6-dihydro-5-fluorouracil:NADP+ 5-oxidoreductase; 5-FU + NADPH + H+ <=> 5,6-Dihydro-5-fluorouracil + NADP+ R08227 5,6-dihydro-5-fluorouracil amidohydrolase; 5,6-Dihydro-5-fluorouracil + H2O <=> alpha-Fluoro-beta-ureidopropionic acid R08228 alpha-fluoro-beta-ureidopropionic acid amidohydrolase; alpha-Fluoro-beta-ureidopropionic acid + H2O <=> alpha-Fluoro-beta-alanine + CO2 + Ammonia R08229 5-fluorouridine:phosphate alpha-D-ribosyltransferase; 5-FU + alpha-D-Ribose 1-phosphate <=> 5-Fluorouridine + Orthophosphate R08230 5-fluorodeoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase; 5-FU + 2-Deoxy-D-ribose 1-phosphate <=> 5-Fluorodeoxyuridine + Orthophosphate R08231 5-fluorouridine monophosphate:diphosphate phospho-alpha-D-ribosyl-transferase; 5-FU + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 5-Fluorouridine monophosphate + Diphosphate R08232 ATP:5-fluorouridine 5'-phosphotransferase; 5-Fluorouridine + ATP <=> 5-Fluorouridine monophosphate + ADP R08233 ATP:5-fluorodeoxyuridine 5'-phosphotransferase; 5-Fluorodeoxyuridine + ATP <=> 5-Fluorodeoxyuridine monophosphate + ADP R08234 Azathioprine <=> 6-Mercaptopurine + 1-Methyl-4-nitroimidazole R08235 6-mercaptopurin:oxygen oxidoreductase; 6-Mercaptopurine + 2 H2O + 2 Oxygen <=> 6-Thiourate + 2 Hydrogen peroxide R08236 S-adenosyl-L-methionine:6-mercaptopurin S-methyltransferase; 6-Mercaptopurine + S-Adenosyl-L-methionine <=> 6-Methylmercaptopurine + S-Adenosyl-L-homocysteine R08237 6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase; 6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate R08238 6-methylthiopurine 5'-monophosphate ribonucleotide:diphosphate phospho-D-ribosyltransferase; 6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate R08239 S-adenosyl-L-methionine:6-thioinosine 5'-monophosphate S-methyltransferase; 6-Thioinosine-5'-monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + S-Adenosyl-L-homocysteine R08240 6-thioinosine 5'-monophosphate:NAD+ oxidoreductase; 6-Thioinosine-5'-monophosphate + NAD+ + H2O <=> 6-Thioxanthine 5'-monophosphate + NADH + H+ R08241 6-Thioinosine-5'-monophosphate + ATP <=> 6-Mercaptopurine ribonucleoside 5'-diphosphate + ADP R08242 6-Mercaptopurine ribonucleoside 5'-diphosphate + ATP <=> 6-Mercaptopurine ribonucleoside triphosphate + ADP R08243 inosine triphosphate pyrophosphatase; 6-Mercaptopurine ribonucleoside triphosphate + H2O <=> 6-Thioinosine-5'-monophosphate + Diphosphate R08244 6-thioxanthine 5'-monophosphate:L-glutamine amido-ligase (AMP-forming); 6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate R08245 6-thioguanosine monophosphate:diphosphate phospho-D-ribosyltransferase; Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate R08246 S-adenosyl-L-methionine:6-thioguanosine monophosphate S-methyltransferase; 6-Thioguanosine monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthioguanosine monophosphate + S-Adenosyl-L-homocysteine R08247 D-ribose pyranase; beta-D-Ribopyranose <=> beta-D-Ribofuranose R08248 acetyl-CoA: isoniazid N-acetyltransferase; Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid R08249 N-acetylisoniazid amidohydrolase; N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid R08250 acetyl-CoA:acetylhydrazine N-acetyltransferase; Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine R08251 isoniazid amidohydrolase; Isoniazid + H2O <=> Isonicotinic acid + Hydrazine R08252 Isonicotinic acid + Glycine <=> Isonicotinylglycine R08253 Isoniazid + Pyruvate <=> Isoniazid pyruvate + H2O R08254 Isoniazid + 2-Oxoglutarate <=> Isoniazid alpha-ketoglutaric acid + H2O R08255 Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid R08256 Irinotecan <=> APC R08257 Irinotecan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> NPC + Glutaral + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08258 NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid R08259 SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP R08260 SN38 glucuronide glucuronosohydrolase; SN38 glucuronide + H2O <=> SN-38 + D-Glucuronate R08261 UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide R08262 Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP R08263 Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP R08264 Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Norcodeine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O R08265 Morphine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Normorphine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O R08266 tamoxifen,NADPH:oxygen oxidoreductase (N-oxide-forming); Tamoxifen + Oxygen + NADPH + H+ <=> Tamoxifen N-oxide + NADP+ + H2O R08267 Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O R08268 Tamoxifen <=> N-Desmethyltamoxifen R08269 Hydroxytamoxifen <=> Endoxifen R08270 N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O R08271 Tamoxifen + NADPH + Oxygen + H+ <=> alpha-Hydroxytamoxifen + NADP+ + H2O R08272 N-Desmethyltamoxifen <=> N,N-Didesmethyltamoxifen R08273 (13Z,16Z)-Docosadienoyl-CoA + H2O <=> CoA + (13Z,16Z)-Docosadienoic acid R08274 N-Desmethyltamoxifen + NADPH + H+ + Oxygen <=> alpha-Hydroxy-N-desmethyltamoxifen + H2O + NADP+ R08275 Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O R08276 Cyclophosphamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde R08277 4-Hydroxycyclophosphamide <=> 4-Ketocyclophosphamide R08278 4-Hydroxycyclophosphamide <=> Aldophosphamide R08279 Aldophosphamide <=> Phosphoramide mustard + Acrolein R08280 4-glutathionyl cyclophosphamide hydrolase; Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O R08281 alcophosphamide:NAD+ oxidoreductase; Aldophosphamide + NADH + H+ <=> Alcophosphamide + NAD+ R08282 carboxyphosphamide:NAD+ oxidoreductase; Aldophosphamide + NAD+ + H2O <=> Carboxyphosphamide + NADH + H+ R08283 carboxyphosphamide:NADP+ oxidoreductase; Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+ R08284 Carboxyphosphamide <=> Nornitrogen mustard R08285 Ifosfamide + NADPH + H+ + Oxygen <=> 4-Hydroxyifosfamide + NADP+ + H2O R08286 Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde R08287 Ifosfamide <=> 2-Dechloroethylifosfamide + Chloroacetaldehyde R08288 4-Hydroxyifosfamide <=> Aldoifosfamide R08289 Aldoifosfamide <=> Isophosphoramide mustard + Acrolein R08290 Aldoifosfamide <=> Alcoifosfamide R08291 4-Hydroxyifosfamide <=> 4-Ketoifosfamide R08292 Aldoifosfamide <=> Carboxyifosfamide R08293 Lidocaine <=> Monoethylglycinexylidide R08294 Lidocaine + NADPH + Oxygen + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O R08295 monoethylglycinexylidide amidohydrolase; Monoethylglycinexylidide + H2O <=> 2,6-Dimethylaniline + N-Ethylglycine R08296 Monoethylglycinexylidide <=> Glycinexylidide R08297 3-Hydroxylidocaine <=> 3-Hydroxymonoethylglycinexylidide R08298 Monoethylglycinexylidide <=> 3-Hydroxymonoethylglycinexylidide R08299 Glycinexylidide <=> 2,6-Dimethylaniline R08300 lidocaine amidohydrolase; Lidocaine + H2O <=> 2,6-Dimethylaniline + N,N-Diethylglycine R08301 2,6-Dimethylaniline <=> 4-Hydroxy-2,6-dimethylaniline R08302 2,6-Dimethylaniline <=> 2-Amino-3-methylbenzoate R08303 Felbamate + NADPH + H+ + Oxygen <=> p-Hydroxyfelbamate + NADP+ + H2O R08304 Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O R08305 Felbamate + H2O <=> 2-Phenyl-1,3-propanediol monocarbamate + CO2 + Ammonia R08306 2-phenyl-1,3-propanediol monocarbamate:NAD+ oxidoreductase; 2-Phenyl-1,3-propanediol monocarbamate + NAD+ <=> 3-Carbamoyl-2-phenylpropionaldehyde + NADH + H+ R08307 3-carbamoyl-2-phenylpropionaldehyde:NAD+ oxidoreductase; 3-Carbamoyl-2-phenylpropionaldehyde + NAD+ + H2O <=> 3-Carbamoyl-2-phenylpropionic acid + NADH + H+ R08308 3-Carbamoyl-2-phenylpropionaldehyde <=> Atropaldehyde + CO2 + Ammonia R08309 3-Carbamoyl-2-phenylpropionaldehyde <=> 4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one R08310 4-hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one:NAD+ oxidoreductase; 4-Hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one + NAD+ <=> 5-Phenyl-1,3-oxazinane-2,4-dione + NADH + H+ R08311 5-Phenyl-1,3-oxazinane-2,4-dione + H2O <=> 3-Carbamoyl-2-phenylpropionic acid R08312 Carbamazepine + NADPH + H+ + Oxygen <=> Carbamazepine-10,11-epoxide + NADP+ + H2O R08313 Carbamazepine + NADPH + H+ + Oxygen <=> 3-Hydroxycarbamazepine + NADP+ + H2O R08314 Carbamazepine-10,11-epoxide + H2O <=> Dihydroxycarbazepine R08315 3-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine R08316 2,3-Dihydroxycarbamazepine <=> Carbamazepine-o-quinone R08317 Carbamazepine <=> 2-Hydroxycarbamazepine R08318 2-Hydroxycarbamazepine <=> 2-Hydroxyiminostilbene R08319 2-Hydroxyiminostilbene <=> 2H-Dibenz[b,f]azepin-2-one R08320 2-Hydroxycarbamazepine <=> 2,3-Dihydroxycarbamazepine R08321 Oxcarbazepine <=> 10-Hydroxycarbazepine R08322 10-Hydroxycarbazepine <=> Dihydroxycarbazepine R08323 7-Mercaptoheptanoic acid + L-Threonine + ATP <=> 7-Mercaptoheptanoylthreonine + ADP + Orthophosphate R08324 Valproic acid <=> 2-n-Propyl-4-pentenoic acid R08325 Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O R08326 Valproic acid + NADPH + H+ + Oxygen <=> 5-Hydroxyvalproic acid + NADP+ + H2O R08327 Valproic acid + NADPH + H+ + Oxygen <=> 3-Hydroxyvalproic acid + NADP+ + H2O R08328 2-Oxosuberate <=> 7-Oxoheptanoic acid + CO2 R08329 2-n-Propyl-4-pentenoic acid <=> 2-Propyl-2,4-pentadienoic acid R08330 4-Hydroxyvalproic acid <=> 2-n-Propyl-4-oxopentanoic acid R08331 acetyl-CoA:2-oxoadipate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming); 2-Oxoadipate + Acetyl-CoA + H2O <=> (R)-(Homo)2-citrate + CoA R08332 acetyl-CoA:2-oxopimelate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming); 2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA R08333 2-n-Propyl-4-oxopentanoic acid <=> 2-Propylsuccinic acid R08334 5-Hydroxyvalproic acid <=> 2-Propylglutaric acid R08335 3-Hydroxyvalproic acid <=> 3-Oxovalproic acid R08336 Valproic acid <=> 2-n-Propyl-2-pentenoic acid R08337 Valproic acid <=> 2-n-Propyl-3-pentenoic acid R08338 2-n-Propyl-2-pentenoic acid <=> 3-Hydroxyvalproic acid R08339 Methadone <=> 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine R08340 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine <=> 2-Ethyl-5-methyl-3,3-diphenyl-1-pyrroline R08341 Levomethadyl acetate <=> L-alpha-Acetyl-N-normethadol R08342 L-alpha-Acetyl-N-normethadol <=> L-alpha-Acetyl-N,N-dinormethadol R08343 Citalopram <=> Demethylcitalopram R08344 Citalopram <=> Citalopram N-oxide R08345 Demethylcitalopram <=> Didemethylcitalopram R08346 citalopram:oxygen oxidoreductase(deaminating)(flavin-containing); Citalopram + Oxygen + H2O <=> Citalopram aldehyde + Dimethylamine + Hydrogen peroxide R08347 demethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing); Demethylcitalopram + Oxygen + H2O <=> Citalopram aldehyde + Methylamine + Hydrogen peroxide R08348 didemethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing); Didemethylcitalopram + H2O + Oxygen <=> Citalopram aldehyde + Ammonia + Hydrogen peroxide R08349 citalopram aldehyde:oxygen oxidoreductase; Citalopram aldehyde + H2O + Oxygen <=> Citalopram propionic acid + Hydrogen peroxide R08350 glutathione:glutathionylspermidine amidase; Trypanothione + H2O <=> Glutathione + Glutathionylspermidine R08351 glutathione:glutathionylaminopropylcadaverine amidase; Homotrypanothione + H2O <=> Glutathione + Glutathionylaminopropylcadaverine R08352 glutathione:spermine ligase (ADP-forming); ATP + Glutathione + Spermine <=> ADP + Orthophosphate + Glutathionylspermine R08353 glutathione:glutathionylspermine ligase (ADP-forming); ATP + Glutathione + Glutathionylspermine <=> ADP + Orthophosphate + Bis(glutathionyl)spermine R08354 glutathione:aminopropylcadaverine ligase (ADP-forming); ATP + Glutathione + Aminopropylcadaverine <=> ADP + Orthophosphate + Glutathionylaminopropylcadaverine R08355 glutathione:glutathionylaminopropylcadaverine ligase (ADP-forming); ATP + Glutathione + Glutathionylaminopropylcadaverine <=> ADP + Orthophosphate + Homotrypanothione R08356 bis(glutathionyl)spermine:NADP+ oxidoreductase; Bis(glutathionyl)spermine + NADP+ <=> Bis(glutathionyl)spermine disulfide + NADPH + H+ R08357 homotrypanothione:NADP+ oxidoreductase; Homotrypanothione + NADP+ <=> Homotrypanothione disulfide + NADPH + H+ R08358 Trypanothione + Dehydroascorbate <=> Trypanothione disulfide + Ascorbate R08359 S-adenosylmethioninamine:cadaverine 3-aminopropyltransferase; S-Adenosylmethioninamine + Cadaverine <=> 5'-Methylthioadenosine + Aminopropylcadaverine R08360 tryparedoxin:hydroperoxide oxidoreductase; Tryparedoxin + ROOH <=> Tryparedoxin disulfide + H2O + ROH R08361 Trypanothione + Tryparedoxin disulfide <=> Trypanothione disulfide + Tryparedoxin R08362 trypanothione:hydroperoxide oxidoreductase; Trypanothione + ROOH <=> Trypanothione disulfide + H2O + ROH R08363 2'-deoxyribonucleoside-diphosphate:tryparedoxin-disulfide 2'-oxidoreductase; 2'-Deoxyribonucleoside diphosphate + Tryparedoxin disulfide + H2O <=> Ribonucleoside diphosphate + Tryparedoxin R08364 2'-deoxyribonucleoside-diphosphate:trypanothione-disulfide 2'-oxidoreductase; 2'-Deoxyribonucleoside diphosphate + Trypanothione disulfide + H2O <=> Ribonucleoside diphosphate + Trypanothione R08365 D-Galactosamine 6-phosphate + H2O <=> D-Tagatose 6-phosphate + Ammonia R08366 protein-N(pi)-phosphohistidine:N-acetyl-D-galactosamine 6-phosphotransferase; N-Acetyl-D-galactosamine + Protein N(pi)-phospho-L-histidine <=> N-Acetyl-D-galactosamine 6-phosphate + Protein histidine R08367 protein-N(pi)-phosphohistidine:D-galactosamine 6-phosphotransferase; D-Galactosamine + Protein N(pi)-phospho-L-histidine <=> D-Galactosamine 6-phosphate + Protein histidine R08368 purine-nucleoside:phosphate ribosyltransferase; N-D-Ribosylpurine + Orthophosphate <=> Purine + alpha-D-Ribose 1-phosphate R08369 UDP-glucose:N6-alkylaminopurine 9-glucosyltransferase; UDP-glucose + N6-Alkylaminopurine <=> UDP + N6-Alkylaminopurine-9-beta-D-glucoside R08370 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming]; trans,trans-Farnesyl diphosphate <=> (E)-alpha-Bisabolene + Diphosphate R08371 2 delta-Cadinene <=> Gossypol R08372 1-Hydroxyalkyl-sn-glycerol <=> Aldehyde + Glycerol R08373 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-humulene-forming); trans,trans-Farnesyl diphosphate <=> Humulene + Diphosphate R08374 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3S,6E)-nerolidol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> Nerolidol + Diphosphate R08376 (S)-2,3-Epoxysqualene <=> Euphol R08377 Euphol <=> Azadirachtin A R08378 (S)-2,3-Epoxysqualene <=> Cucurbitacin E R08379 retinol: NADP+ oxidoreductase; Retinol + NADP+ <=> Retinal + NADPH + H+ R08380 11-cis-retinol: NADP+ oxidoreductase; 11-cis-Retinol + NADP+ <=> 11-cis-Retinal + NADPH + H+ R08381 palmitoyl-CoA:retinol O-acyltransferase; Palmitoyl-CoA + 11-cis-Retinol <=> CoA + 11-cis-Retinyl palmitate R08382 9-cis-retinol:NAD+ oxidoreductase; 9-cis-Retinol + NAD+ <=> 9-cis-Retinal + NADH + H+ R08383 9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+ R08384 retinal:oxygen oxidoreductase; 9-cis-Retinal + Oxygen + H2O <=> 9-cis-Retinoic acid + Hydrogen peroxide R08385 retinal:NAD+ oxidoreductase; 9-cis-Retinal + NAD+ + H2O <=> 9-cis-Retinoic acid + NADH + H+ R08386 acetyl-CoA:N-hydroxyarylamine O-acetyltransferase; Acetyl-CoA + N-Hydroxyarylamine <=> CoA + N-Acetoxyarylamine R08387 phosphatidylcholine:retinol O-acyltransferase; Phosphatidylcholine + Retinol <=> 2-Acyl-sn-glycero-3-phosphocholine + Retinyl ester R08388 all-trans-retinyl ester acylhydrolase, 11-cis-retinol forming; Retinyl ester + H2O <=> 11-cis-Retinol + Fatty acid R08389 phosphatidylcholine:retinol O-acyltransferase; Palmitoylphosphatidylcholine + 11-cis-Retinol <=> 11-cis-Retinyl palmitate + 2-Acyl-sn-glycero-3-phosphocholine R08390 Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-18-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R08391 Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O R08392 Retinoate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> all-trans-4-Hydroxyretinoic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R08393 Geranyl diphosphate <=> Nerol R08394 Geranyl diphosphate <=> cis-Citral R08395 Geranyl diphosphate <=> Car-3-ene + Diphosphate R08396 geranyl-diphosphate diphosphohydrolase; Geranyl diphosphate + H2O <=> Geraniol + Diphosphate R08397 Geranyl diphosphate <=> beta-Citronellol R08398 Geranyl diphosphate <=> Geranial R08399 Geranyl diphosphate <=> (R)-(+)-Citronellal R08400 poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenyl-cis-transferase; poly-cis-Polyprenyl diphosphate + Isopentenyl diphosphate <=> poly-cis-Polyprenyl diphosphate longer by one C5 unit + Diphosphate R08401 ent-Kaurene <=> Stevioside R08402 Levopimaradiene <=> Ginkgolide A R08403 DNA 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine <=> DNA containing guanine + H2O R08404 acyl-phosphate:D-glucose phosphotransferase; Acyl phosphate + D-Glucose <=> Carboxylate + D-Glucose 6-phosphate R08405 acyl-phosphate:D-mannose phosphotransferase; Acyl phosphate + D-Mannose <=> Carboxylate + D-Mannose 6-phosphate R08406 acyl-phosphate:D-fructose phosphotransferase; Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 6-phosphate R08407 acyl-phosphate:D-fructose phosphotransferase; Acyl phosphate + D-Fructose <=> Carboxylate + D-Fructose 1-phosphate R08408 aldehyde:oxygen oxidoreductase; 1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-2-pyridone-5-carboxamide + Hydrogen peroxide + H+ R08409 plastoquinol:oxidized-plastocyanin oxidoreductase; Plastoquinol-9 + 2 Oxidized plastocyanin + 2 H+ <=> Plastoquinone-9 + 2 Reduced plastocyanin + 4 H+ R08410 Xanthine + 2 S-Adenosyl-L-methionine <=> Theophylline + 2 S-Adenosyl-L-homocysteine R08411 L-Leucine <=> 3-Methylbutanoic acid R08412 L-Histidine + 3-Methylbutanoic acid <=> Dolichotheline R08413 L-Histidine <=> Pilocarpine R08414 (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate <=> L-Pipecolate R08415 L-Pipecolate <=> 1-Indolizidinone R08416 1-Indolizidinone <=> Swainsonine R08417 1-Indolizidinone <=> Slaframine R08418 Cadaverine <=> Lupinine R08419 Cadaverine <=> (-)-Sparteine R08420 (-)-Sparteine <=> Cytisine R08421 Cadaverine <=> Lupanine R08422 Piperideine + trans-Cinnamate <=> (-)-Sedamine R08423 Piperideine + trans-Cinnamate + Benzoyl-CoA <=> Lobelanine + CoA R08424 Lobelanine <=> Lobeline R08425 N-Methylpelletierine <=> Pseudopelletierine R08426 Nicotinate <=> 3,6-Dihydronicotinic acid R08427 1-Methylpyrrolinium <=> Cuscohygrine R08428 1-Methylpyrrolinium <=> (-)-Hygrine R08429 1-Methylpyrrolinium <=> Ecgonine methyl ester R08430 Ecgonine methyl ester + Benzoyl-CoA <=> Cocaine + CoA R08431 1-Methylpyrrolinium <=> Tropinone R08432 phenyllactylglucose:tropine O-phenyllactyltransferase; Tropine + Phenyllactylglucose <=> Littorine + D-Glucose R08433 acetyl-CoA:corrinoid protein O-acetyltransferase; Acetyl-CoA + Co(I) corrinoid protein + H+ <=> CO + Methyl-Co(III) corrinoid protein + CoA R08434 Hyoscyamine aldehyde <=> L-Hyoscyamine R08435 4-Coumarate <=> 3,4-Dihydroxybenzaldehyde R08436 Tyramine + 3,4-Dihydroxybenzaldehyde <=> Norcraugsodine + H2O R08437 S-adenosyl-L-methionine:norbelladine O-methyltransferase; Norbelladine + S-Adenosyl-L-methionine <=> 4'-O-Methylnorbelladine + S-Adenosyl-L-homocysteine R08438 4'-O-Methylnorbelladine <=> Noroxopluviine R08439 (4aR,10bS)-Normaritidine <=> Crinine R08440 4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Demethylnarwedine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08441 S-adenosyl-L-homocysteine:norgalanthamine N-methyltransferase; Norgalanthamine + S-Adenosyl-L-methionine <=> Galanthamine + S-Adenosyl-L-homocysteine R08442 N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+ R08443 3,4-Dihydroxy-L-phenylalanine <=> (-)-Salsolinol R08444 Dopamine <=> Mescaline R08445 Dopamine <=> Anhalamine R08446 Anhalonidine + S-Adenosyl-L-methionine <=> Anhalonine + S-Adenosyl-L-homocysteine R08447 Dopamine + 4-Hydroxydihydrocinnamaldehyde <=> (S)-Autumnaline R08448 (S)-Autumnaline + NADPH + Oxygen + H+ <=> Isoandrocymbine + NADP+ + 2 H2O R08449 S-adenosyl-L-methionine:isoandrocymbine O-methyltransferase; Isoandrocymbine + S-Adenosyl-L-methionine <=> O-Methylandrocymbine + S-Adenosyl-L-homocysteine R08450 O-Methylandrocymbine <=> N-Formyldemecolcine R08451 N-Formyldemecolcine + H2O <=> Demecolcine + Formate R08452 Demecolcine <=> Deacetylcolchicine R08453 Deacetylcolchicine + Acetyl-CoA <=> Colchicine + CoA R08454 (S)-Autumnaline <=> Floramultine R08455 Floramultine + S-Adenosyl-L-methionine <=> Kreysigine + S-Adenosyl-L-homocysteine R08456 (S)-Coclaurine <=> (S)-6-O-Methylnorlaudanosoline R08458 (S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine <=> Tubocurarine R08459 2 (S)-N-Methylcoclaurine <=> (+)-Tetrandrine R08460 (S)-Reticuline <=> (S)-Isoboldine R08462 limonin-D-ring-lactone lactonohydrolase; Limonin + H2O <=> Limonoate A-ring-lactone R08463 L-Phenylalanine <=> Cathinone R08464 Cathinone <=> D-Cathine R08465 S-adenosyl-L-methionine:D-cathine N-methyltransferase; D-Cathine + S-Adenosyl-L-methionine <=> (+)-(1S,2S)-Pseudoephedrine + S-Adenosyl-L-homocysteine R08466 Cathinone <=> (-)-Norephedrine R08467 S-adenosyl-L-methionine:norephedrine N-methyltransferase; (-)-Norephedrine + S-Adenosyl-L-methionine <=> Ephedrine + S-Adenosyl-L-homocysteine R08468 S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase; S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine R08469 S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase; S-Adenosyl-L-methionine + Peptide 2-[3-carboxy-3-(dimethylammonio)propyl]-L-histidine <=> S-Adenosyl-L-homocysteine + Peptide diphthine R08470 1,3-Dihydroxy-N-methylacridone <=> Melicopicine R08471 1,3-Dihydroxy-N-methylacridone <=> Acronycine R08472 1,3-Dihydroxy-N-methylacridone <=> Rutacridone R08473 Anthranilate <=> 4-Hydroxy-2-quinolone R08474 4-Hydroxy-2-quinolone <=> Platydesmine R08475 Platydesmine <=> Dictamnine R08476 Dictamnine <=> Skimmianine R08477 Anthranilate + 1-Pyrroline <=> Peganine R08478 N-Acetylanthranilate + L-Aspartate <=> Peganine R08480 ATP:psilocin 4-phosphotransferase; ATP + Psilocin <=> ADP + Psilocybin R08481 Tryptamine <=> Physostigmine R08482 Tryptamine <=> Harman R08483 Tryptamine <=> Calligonine R08484 Tryptamine <=> Harmaline R08485 Harmaline <=> Harmine R08486 Harmaline <=> Tetrahydroharmine R08487 3-alpha(S)-Strictosidine <=> Strictosamide R08488 Strictosamide <=> Pumiloside R08489 Pumiloside <=> Deoxypumiloside R08490 Deoxypumiloside <=> Camptothecin R08491 Corynantheal <=> Cinchoninone R08492 cinchoninone:NADPH oxidoreductase; Cinchoninone + NADPH + H+ <=> Cinchonine + NADP+ R08494 quinidinone:NADPH oxidoreductase; Quinidinone + NADPH + H+ <=> Quinidine + NADP+ R08496 3-alpha(S)-Strictosidine <=> Corynantheal R08497 Corynantheal <=> Quinidinone R08498 Corynantheal <=> Cinchonamine R08499 (6E)-8-hydroxygeraniol:NADP+ oxidoreductase; (6E)-8-Hydroxygeraniol + 2 NADP+ <=> (6E)-8-Oxogeranial + 2 NADPH + 2 H+ R08500 Secologanin <=> Gentiopicrin R08501 Geraniol <=> beta-Skytanthine R08502 Geraniol <=> Actinidine R08503 5-deoxy-D-glucuronate aldose-ketose-isomerase; 5-Deoxy-D-glucuronate <=> 2-Deoxy-5-keto-D-gluconic acid R08505 cholesterol 26-hydroxylase; Cholesterol + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> Cholest-5-ene-3beta,26-diol + H2O + 2 Oxidized adrenal ferredoxin R08506 Cholest-5-ene-3beta,26-diol <=> Solasodine R08507 16alpha,22,26-Trihydroxycholesterol <=> Tomatidine R08508 16alpha,22,26-Trihydroxycholesterol <=> Solanidine R08509 Octanoic acid <=> gamma-Coniceine R08510 gamma-Coniceine + NADPH + H+ <=> Coniine + NADP+ R08511 R-nitrile:glutathione R-transferase; Nitrile + Glutathione <=> Hydrogen cyanide + R-S-Glutathione R08512 R-sulfate-ester:glutathione R-transferase; Sulfuric monoester + Glutathione <=> Sulfate + R-S-Glutathione R08513 Dopamine <=> Anhalonidine R08514 phosphoramidate:hexose 1-phosphotransferase; Phosphoramidate + D-Glucose <=> D-Glucose 1-phosphate + Ammonia R08515 ADP:alpha-D-aldose-1-phosphate adenylyltransferase; ADP + D-Glucose 1-phosphate <=> Orthophosphate + ADP-glucose R08517 17alpha-hydroxypregnenolone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing); 17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Dehydroepiandrosterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O R08518 17alpha-hydroxyprogesterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing); 17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Androstenedione + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O R08519 L-Tyrosyl-tRNA(Tyr) <=> [Thyroglobulin]-L-tyrosine R08520 [Thyroglobulin]-L-tyrosine + Iodine <=> [Thyroglobulin]-3-iodo-L-tyrosine + Hydroiodic acid R08521 [Thyroglobulin]-3-iodo-L-tyrosine + Iodine <=> [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydroiodic acid R08522 [Thyroglobulin]-3,5-diiodo-L-tyrosine + [Thyroglobulin]-3-iodo-L-tyrosine + Hydrogen peroxide <=> Thyroglobulin triiodothyronine + Thyroglobulin dehydroalanine + 2 H2O R08523 2 [Thyroglobulin]-3,5-diiodo-L-tyrosine + Hydrogen peroxide <=> [Thyroglobulin]-L-thyroxine + Thyroglobulin dehydroalanine + 2 H2O R08524 Thyroglobulin triiodothyronine <=> Triiodothyronine R08525 [Thyroglobulin]-L-thyroxine <=> Thyroxine R08527 arachidonate 5-lipoxygenase; Arachidonate + Oxygen <=> Leukotriene A4 + H2O R08528 Z-farnesyl diphosphate synthase; Geranyl diphosphate + Isopentenyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate + Diphosphate R08529 monoterpenyl-diphosphate pyrophosphohydrolase; (+)-Bornyl diphosphate + H2O <=> (+)-Borneol + Diphosphate R08530 acetyl-CoA:monoterpenol O-acetyltransferase; Acetyl-CoA + (-)-Menthol <=> CoA + (-)-Menthyl acetate R08531 acetyl-CoA:monoterpenol O-acetyltransferase; Acetyl-CoA + (+)-Neomenthol <=> CoA + Neomenthyl acetate R08532 acetyl-CoA:monoterpenol O-acetyltransferase; Acetyl-CoA + (+)-Borneol <=> CoA + Bornyl acetate R08533 UDPglucose:sinapate 4-O-beta-D-glucosyltransferase; UDP-glucose + Sinapate <=> UDP + 4-O-beta-D-Glucosyl-sinapate R08534 hydroxycinnamoyl glucosyltransferase; UDP-glucose + 4-Coumarate <=> UDP + p-Coumaroyl-D-glucose R08535 Squalene <=> Hopane-29-acetate R08536 L-glucitol:NAD+ 2-oxidoreductase; L-Glucitol + NAD+ <=> L-Fructose + NADH + H+ R08537 S-adenosyl-L-methionine:amine N-methyltransferase; S-Adenosyl-L-methionine + N-Methylserotonin <=> S-Adenosyl-L-homocysteine + Bufotenine R08538 S-adenosyl-L-methionine:5-hydroxyfuranocoumarin O-methyltransferase; S-Adenosyl-L-methionine + 5-Hydroxyxanthotoxin <=> S-Adenosyl-L-homocysteine + Isopimpinellin R08539 NADPH:ferricytochrome-b5 oxidoreductase; NADPH + 2 Ferricytochrome b5 <=> NADP+ + 2 Ferrocytochrome b5 R08540 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (gamma-humulene-forming); trans,trans-Farnesyl diphosphate <=> gamma-Humulene + Diphosphate R08541 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (caryophyllene-forming); trans,trans-Farnesyl diphosphate <=> beta-Caryophyllene + Diphosphate R08542 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (longifolene-forming); trans,trans-Farnesyl diphosphate <=> Longifolene + Diphosphate R08543 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (adding water;acetone-geosmin-forming); trans,trans-Farnesyl diphosphate + 2 H2O <=> Geosmin + Diphosphate + Acetone R08544 D-galactose:NAD+ 1-oxidoreductase; D-Galactose + NAD+ <=> D-Galactono-1,5-lactone + NADH + H+ R08545 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (germacrene-B-forming); trans,trans-Farnesyl diphosphate <=> Germacrene B + Diphosphate R08546 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (beta-selinene-forming); trans,trans-Farnesyl diphosphate <=> beta-Selinene + Diphosphate R08547 S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase; S-Adenosyl-L-methionine + L-Tryptophan <=> S-Adenosyl-L-homocysteine + L-2-Methyltryptophan R08548 D-Fructose 1-phosphate + H2O <=> D-Fructose + Orthophosphate R08549 2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex; 2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+ R08550 protein N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase; [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + NAD+ <=> Protein N6-(lipoyl)lysine + NADH + H+ R08551 cytochrome P-450 reductase; [Oxidized NADPH---hemoprotein reductase] + NADPH + H+ <=> [Reduced NADPH---hemoprotein reductase] + NADP+ R08553 AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming); AMP + Sulfite + FAD <=> Adenylyl sulfate + FADH2 R08555 (R)-lactate hydro-lyase (adding N-acetyl-D-glucosamine 6-phosphate; N-acetylmuramate 6-phosphate-forming); (R)-Lactate + N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetylmuramic acid 6-phosphate + H2O R08557 Choline + NAD+ <=> Betaine aldehyde + NADH + H+ R08558 Choline + NADP+ <=> Betaine aldehyde + NADPH + H+ R08559 protein-N(pi)-phosphohistidine:N-acetylmuramate 6-phosphotransferase; N-Acetylmuramate + Protein N(pi)-phospho-L-histidine <=> N-Acetylmuramic acid 6-phosphate + Protein histidine R08560 cinchoninone epimerase; Cinchonidinone <=> Cinchoninone R08561 cinchoninone:NADPH oxidoreductase (epimerizing); Cinchoninone + NADPH + H+ <=> Cinchonidine + NADP+ R08562 quinidinone:NADPH oxidoreductase (epimerizing); Quinidinone + NADPH + H+ <=> Quinine + NADP+ R08563 cinchonidinone:NADPH oxidoreductase; Cinchonidinone + NADPH + H+ <=> Cinchonidine + NADP+ R08564 Corynantheal <=> Cinchonidinone R08566 4-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-3-methylbutanoylating); 4-Methyl-2-oxopentanoate + CoA + 2 Oxidized ferredoxin <=> 3-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+ R08567 (S)-3-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylbutanoylating); (S)-3-Methyl-2-oxopentanoic acid + CoA + 2 Oxidized ferredoxin <=> (S)-2-Methylbutanoyl-CoA + CO2 + 2 Reduced ferredoxin + H+ R08568 L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase; L-Aspartate 4-semialdehyde + 6-Deoxy-5-ketofructose 1-phosphate <=> 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + Hydroxypyruvaldehyde phosphate R08569 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating); 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + H2O + NAD+ <=> 3-Dehydroquinate + Ammonia + NADH + H+ R08570 2-dehydro-3-deoxy-D-gluconate D-glyceraldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-D-gluconate <=> D-Glyceraldehyde + Pyruvate R08571 glyceraldehyde ferredoxin oxidoreductase; D-Glyceraldehyde + H2O + Oxidized ferredoxin <=> D-Glycerate + H+ + Reduced ferredoxin R08572 ATP:(R)-glycerate 2-phosphotransferase; D-Glycerate + ATP <=> 2-Phospho-D-glycerate + ADP R08573 D-threitol:NADP+ oxidoreductase; D-Threitol + NADP+ <=> D-Erythrulose + NADPH + H+ R08574 CTP:riboflavin 5'-phosphotransferase; CTP + Riboflavin <=> CDP + FMN R08575 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase; Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Fructose 6-phosphate R08576 O-phospho-L-serine:tRNA(Cys) ligase (AMP-forming); O-Phospho-L-serine + tRNA(Cys) + ATP <=> O-Phosphoseryl-tRNA(Cys) + Diphosphate + AMP R08577 O-phospho-L-seryl-tRNACys:hydrogen sulfide 2-aminopropanoate transferase; O-phosphoseryl-tRNA(Cys):hydrogen-sulfide 2-amino-2-[tRNA(Cys)-carbonyl]ethyltransferase; O-Phosphoseryl-tRNA(Cys) + Hydrogen sulfide <=> L-Cysteinyl-tRNA(Cys) + Orthophosphate R08578 L-pyrrolysine:tRNA(Pyl) ligase (AMP-forming); ATP + L-Pyrrolysine + tRNA(Pyl) <=> AMP + Diphosphate + L-Pyrrolysyl-tRNA(Pyl) R08579 parathion oxidoreductase; Parathion <=> Paraoxon R08583 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase (dTDP-3-oxo-4,6-dideoxy-D-glucose-forming); dTDP-4-amino-4,6-dideoxy-D-glucose + S-Adenosyl-L-methionine + Reduced acceptor <=> dTDP-3-oxo-4,6-dideoxy-D-glucose + Ammonia + L-Methionine + 5'-Deoxyadenosine + Acceptor R08584 chlorophyll-a magnesium-lyase (pheophytin-a-forming); Chlorophyll a + 2 H+ <=> Pheophytin a + Magnesium cation R08585 Chlorophyll a <=> Chlorophyll b R08587 futalosine ribohydrolase; Futalosine + H2O <=> Dehypoxanthine futalosine + Hypoxanthine R08588 dehypoxanthine futalosine:S-adenosyl-L-methionine oxidoreductase (cyclizing); Dehypoxanthine futalosine + S-Adenosyl-L-methionine <=> Cyclic dehypoxanthine futalosine + 5'-Deoxyadenosine + L-Methionine R08589 cyclic dehypoxanthine futalosine lyase (dihydroxyacetone-forming); Cyclic dehypoxanthine futalosine <=> 1,4-Dihydroxy-6-naphthoate + Glycerone R08590 3-sulfolactate:NAD+ oxidoreductase; 3-Sulfopyruvate + NADH + H+ <=> 3-Sulfolactate + NAD+ R08591 dTDP-2,6-dideoxy-L-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-L-glucose R08596 1,4-Dihydroxy-6-naphthoate <=> Menaquinone R08597 dTDP-4-oxo-2,6-dideoxy-D-glucose 3,5-epimerase; dTDP-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose R08599 GDP-D-mannose + G10694 <=> GDP + G01813 R08600 N-acetyl-4-O-acetylneuraminate 4-O-acetylhydrolase; N-Acetyl-4-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate R08601 N-acetyl-9-O-acetylneuraminate 9-O-acetylhydrolase; N-Acetyl-9-O-acetylneuraminate + H2O <=> N-Acetylneuraminate + Acetate R08602 S-palmitoylprotein hydrolase; S-Palmitoylprotein + H2O <=> Hexadecanoic acid + [Protein]-L-cysteine R08603 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); 3D-3,5/4-Trihydroxycyclohexane-1,2-dione + H2O <=> 5-Deoxy-D-glucuronate R08604 tryptamine,NADPH:oxygen oxidoreductase (N-hydroxylating); Tryptamine + Oxygen + NADPH <=> N-Hydroxyl-tryptamine + H2O + NADP+ R08605 N-hydroxyl-tryptamine oxidoreductase; N-Hydroxyl-tryptamine <=> Indole-3-acetaldehyde oxime R08606 Indole-3-acetaldehyde oxime <=> Indole-3-acetaldehyde R08607 indole-3-acetaldehyde-oxime,NADPH:oxidoreductase; Indole-3-acetaldehyde oxime + NADPH + Oxygen + H+ <=> Indole-3-acetaldoxime N-oxide + NADP+ + H2O R08608 Indole-3-acetaldoxime N-oxide + L-Cysteine <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O R08609 Indole <=> Indole-3-acetate R08610 5-hydroxymethyluracil,2-oxoglutarate:oxygen oxidoreductase; 5-Hydroxymethyluracil + 2-Oxoglutarate + Oxygen <=> Uracil 5-carbaldehyde + Succinate + CO2 + H2O R08611 5-formyluracil,2-oxoglutarate:oxygen oxidoreductase; Uracil 5-carbaldehyde + 2-Oxoglutarate + Oxygen <=> Uracil 5-carboxylate + Succinate + CO2 R08612 4-beta-D-mannan mannanohydrolase; 1,4-beta-D-Mannan + H2O <=> 1,4-beta-D-Mannooligosaccharide + 1,4-beta-D-Mannan R08613 beta-D-mannoside mannohydrolase; beta-D-Mannoside + H2O <=> ROH + D-Mannose R08614 1,4-beta-D-mannooligosaccharide mannohydrolase; 1,4-beta-D-Mannooligosaccharide + H2O <=> D-Mannose + 1,4-beta-D-Mannooligosaccharide R08615 UDP-glucuronate glucuronohydrolase; UDP-glucuronate + H2O <=> UDP + D-Glucuronate R08616 raffinose:raffinose 3F-alpha-D-galactosyltransferase; 2 Raffinose <=> Isolychnose + Sucrose R08617 D-glucose-6-phosphate phosphate-lyase (2-deoxy-scyllo-inosose-forming); D-Glucose 6-phosphate <=> 2-Deoxy-scyllo-inosose + Orthophosphate R08618 L-methionine:2-oxo-acid aminotransferase; L-Methionine + 2-Oxo acid <=> 4-Methylthio-2-oxobutanoic acid + L-Amino acid R08619 acetyl-CoA:4-methylthio-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 4-Methylthio-2-oxobutanoic acid + Acetyl-CoA + H2O <=> 2-(2'-Methylthio)ethylmalic acid + CoA R08620 2-(2'-methylthio)ethylmalate hydroxymutase; 2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid R08621 3-(2'-methylthio)ethylmalate:NAD+ oxidoreductase (decarboxylating); 3-(2'-Methylthio)ethylmalic acid + NAD+ <=> 2-Oxo-5-methylthiopentanoic acid + CO2 + NADH + H+ R08622 homomethionine:2-oxo-acid aminotransferase; 2-Oxo-5-methylthiopentanoic acid + L-Amino acid <=> Homomethionine + 2-Oxo acid R08623 acetyl-CoA:5-methylthio-2-oxopentanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=> 2-(3'-Methylthio)propylmalic acid + CoA R08624 2-(3'-methylthio)propylmalate hydroxymutase; 2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid R08625 3-(3'-methylthio)propylmalate:NAD+ oxidoreductase (decarboxylating); 3-(3'-Methylthio)propylmalic acid + NAD+ <=> 2-Oxo-6-methylthiohexanoic acid + CO2 + NADH + H+ R08626 dihomomethionine:2-oxo-acid aminotransferase; 2-Oxo-6-methylthiohexanoic acid + L-Amino acid <=> Dihomomethionine + 2-Oxo acid R08627 acetyl-CoA:6-methylthio-2-oxohexanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo-6-methylthiohexanoic acid + Acetyl-CoA + H2O <=> 2-(4'-Methylthio)butylmalic acid + CoA R08628 2-(3'-methylthio)butylmalate hydroxymutase; 2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid R08629 3-(4'-methylthio)butylmalate:NAD+ oxidoreductase (decarboxylating); 3-(4'-Methylthio)butylmalic acid + NAD+ <=> 2-Oxo-7-methylthioheptanoic acid + CO2 + NADH + H+ R08630 trihomomethionine:2-oxo-acid aminotransferase; 2-Oxo-7-methylthioheptanoic acid + L-Amino acid <=> Trihomomethionine + 2-Oxo acid R08631 acetyl-CoA:7-methylthio-2-oxoheptanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo-7-methylthioheptanoic acid + Acetyl-CoA + H2O <=> 2-(5'-Methylthio)pentylmalic acid + CoA R08632 L-cystathionine cysteine-lyase; L-Cystathionine <=> L-Cysteine + 2-Aminobut-2-enoate R08633 L-homocysteine hydrogen-sulfide-lyase; L-Homocysteine <=> Hydrogen sulfide + 2-Aminobut-2-enoate R08634 2-(3'-methylthio)pentylmalate hydroxymutase; 2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid R08635 L-methionine methanethiol-lyase; L-Methionine <=> Methanethiol + 2-Aminobut-2-enoate R08636 3-(5'-methylthio)pentylmalate:NAD+ oxidoreductase (decarboxylating); 3-(5'-Methylthio)pentylmalic acid + NAD+ <=> 2-Oxo-8-methylthiooctanoic acid + CO2 + NADH + H+ R08637 2-aminobut-2-enoate aminohydrolase (spontaneous); 2-Aminobut-2-enoate + H2O <=> 2-Oxobutanoate + Ammonia R08638 tetrahomomethionine:2-oxo-acid aminotransferase; 2-Oxo-8-methylthiooctanoic acid + L-Amino acid <=> Tetrahomomethionine + 2-Oxo acid R08639 alpha-D-glucose 1,6-phosphomutase; D-Glucose 1-phosphate <=> D-Glucose 6-phosphate R08640 acetyl-CoA:8-methylthio-2-oxooctanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=> 2-(6'-Methylthio)hexylmalic acid + CoA R08641 2-(3'-methylthio)hexylmalate hydroxymutase; 2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid R08642 3-(6'-methylthio)hexylmalate:NAD+ oxidoreductase (decarboxylating); 3-(6'-Methylthio)hexylmalic acid + NAD+ <=> 2-Oxo-9-methylthiononanoic acid + CO2 + NADH + H+ R08643 pentahomomethionine:2-oxo-acid aminotransferase; 2-Oxo-9-methylthiononanoic acid + L-Amino acid <=> Pentahomomethionine + 2-Oxo acid R08644 acetyl-CoA:9-methylthio-2-oxononanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo-9-methylthiononanoic acid + Acetyl-CoA + H2O <=> 2-(7'-Methylthio)heptylmalic acid + CoA R08645 2-(3'-methylthio)heptylmalate hydroxymutase; 2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid R08646 3-(7'-methylthio)heptylmalate:NAD+ oxidoreductase (decarboxylating); 3-(7'-Methylthio)heptylmalic acid + NAD+ <=> 2-Oxo-10-methylthiodecanoic acid + CO2 + NADH + H+ R08647 hexahomomethionine:2-oxo-acid aminotransferase; 2-Oxo-10-methylthiodecanoic acid + L-Amino acid <=> Hexahomomethionine + 2-Oxo acid R08648 pyruvate:2-oxobutanoate acetaldehydetransferase (decarboxylating); Pyruvate + 2-Oxobutanoate <=> (S)-2-Aceto-2-hydroxybutanoate + CO2 R08650 L-Aspartate 4-semialdehyde + Glycerone phosphate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O R08651 D-fructose:NADP+ 5-oxidoreductase; D-Fructose + NADP+ <=> 5-Dehydro-D-fructose + NADPH + H+ R08652 L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating); L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (Z)-Phenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08653 (Z)-phenylacetaldehyde-oxime,NADPH:oxygen oxidoreductase (adding cysteine); (Z)-Phenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O R08654 S-(phenylacetothiohydroximoyl)-L-cysteine phenylacetothiohydroximate-lyase (deaminating; pyruvate-forming); S-(Phenylacetothiohydroximoyl)-L-cysteine + H2O <=> Phenylacetothiohydroximate + Pyruvate + Ammonia R08655 L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating); L-Homophenylalanine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Phenylpropionaldoxim + 2 NADP+ + CO2 + 3 H2O R08657 sn-glycerol 3-phosphate:ubiquinone oxidoreductase; sn-Glycerol 3-phosphate + Ubiquinone <=> Glycerone phosphate + Ubiquinol R08658 glycerol-1-phosphate phosphohydrolase; DL-Glycerol 1-phosphate + H2O <=> Glycerol + Orthophosphate R08659 (Z)-4-hydroxyphenylacetaldehyde-oxime,NADPH:oxygen oxidoreductase (adding cysteine); (Z)-4-Hydroxyphenylacetaldehyde oxime + Oxygen + NADPH + L-Cysteine + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O R08660 S-(hydroxyphenylacetothiohydroximoyl)-L-cysteine phenylacetothiohydroximate-lyase (deaminating; pyruvate-forming); S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + H2O <=> p-Hydroxyphenylacetothiohydroximate + Pyruvate + Ammonia R08661 UDP-glucose:p-hydroxyphenylacetothiohydroximate S-beta-D-glucosyltransferase; p-Hydroxyphenylacetothiohydroximate + UDP-glucose <=> p-Hydroxybenzyldesulphoglucosinolate + UDP R08662 3'-phosphoadenylyl-sulfate:desulfo-p-hydroxybenzylglucosinolate sulfotransferase; p-Hydroxybenzyldesulphoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Sinalbin + Adenosine 3',5'-bisphosphate R08663 L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Valine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylpropanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08664 L-leucine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating); L-Leucine + 2 Oxygen + 2 NADPH + 2 H+ <=> 3-Methylbutyraldehyde oxime + 3 H2O + 2 NADP+ + CO2 R08665 homomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Homomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 4-Methylthiobutanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08666 4-methylthiobutanaldoxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (adding cysteine); 4-Methylthiobutanaldoxime + L-Cysteine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08667 S-(4-methylthiobutylthiohydroximoyl)-L-cysteine 4-methylthiobutylthiohydroximate-lyase (deaminating; pyruvate-forming); S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + H2O <=> 4-Methylthiobutylthiohydroximate + Pyruvate + Ammonia R08668 UDP-glucose:4-methylthiobutylthiohydroximate S-beta-D-glucosyltransferase; 4-Methylthiobutylthiohydroximate + UDP-glucose <=> 3-Methylthiopropyl-desulfoglucosinolate + UDP R08669 3'-phosphoadenylyl-sulfate:3-methylthiopropyl-desulfoglucosinolate sulfotransferase; 3-Methylthiopropyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoiberverin + Adenosine 3',5'-bisphosphate R08670 dihomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Dihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 5-Methylthiopentanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08671 3'-phosphoadenylyl-sulfate:4-methylthiobutyl-desulfoglucosinolate sulfotransferase; 4-Methylthiobutyl-desulfoglucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucoerucin + Adenosine 3',5'-bisphosphate R08672 trihomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Trihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 6-Methylthiohexanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08673 tetrahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Tetrahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 7-Methylthioheptanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08674 pentahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Pentahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 8-Methylthiooctanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08675 hexahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; Hexahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 9-Methylthiononanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R08676 ADP-glucose:D-fructose 2-alpha-D-glucosyltransferase; ADP + Sucrose <=> ADP-glucose + D-Fructose R08678 S-sulfanylglutathione:oxygen oxidoreductase; S-Sulfanylglutathione + Oxygen + H2O <=> Glutathione + Sulfite R08679 amino acid:2-oxo-acid aminotransferase; Amino acid + 2-Oxo acid <=> Amino acid + 2-Oxo acid R08680 acetyl-CoA:2-oxo-acid C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); 2-Oxo acid + Acetyl-CoA + H2O <=> 2-Alkylmalic acid + CoA R08681 2-alkylmalate hydroxymutase; 2-Alkylmalic acid <=> 3-Alkylmalic acid R08682 3-alkylmalate oxidoreductase (decarboxylating); 3-Alkylmalic acid <=> Aliphatic oxo acid + CO2 R08683 amino acid:2-oxo-acid aminotransferase; Aliphatic oxo acid + Amino acid <=> Homoamino acid + 2-Oxo acid R08684 amino-acid,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating); Amino acid + 2 Oxygen + 2 NADPH + 2 H+ <=> Aldoxime + 2 NADP+ + 3 H2O + CO2 R08685 aldoxime,NADPH:oxygen oxidoreductase (adding cysteine); Aldoxime + NADPH + Oxygen + L-Cysteine + H+ <=> S-Alkyl-thiohydroximate + NADP+ + 2 H2O R08686 S-thiohydroximoyl-L-cysteine thiohydroximate-lyase (deaminating; pyruvate-forming); S-Alkyl-thiohydroximate + H2O <=> Thiohydroximic acid + Pyruvate + Ammonia R08687 UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase; Thiohydroximic acid + UDP-glucose <=> desulfo-Glucosinolate + UDP R08688 3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase; desulfo-Glucosinolate + 3'-Phosphoadenylyl sulfate <=> Glucosinolate + Adenosine 3',5'-bisphosphate R08689 (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase (hydrating); 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + 2 Reduced ferredoxin <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + H2O + 2 Oxidized ferredoxin R08690 side chain-elongation; L-Phenylalanine <=> L-Homophenylalanine R08691 trans,trans-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-valencene-forming]; (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-valencene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-Valencene + Diphosphate R08692 GDP-D-mannuronate:poly(beta-D-mannuronate) beta-D-mannuronyltransferase; GDP-D-mannuronate + (beta-D-Mannuronate)n <=> (beta-D-Mannuronate)n + GDP R08693 poly(beta-D-mannuronate) C5-epimerase; (beta-D-Mannuronate)n <=> (Alginate)n R08694 (1->4)-alpha-D-galacturonan lyase; poly(1,4-alpha-D-galacturonate)lyase; Pectate <=> Oligosaccharide with 4-deoxy-alpha-D-gluc-4-enuronosyl group + Pectate R08695 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-beta-farnesene-forming]; trans,trans-farnesyl-diphosphate diphosphate-lyase (beta-farnesene-forming); trans,trans-Farnesyl diphosphate <=> beta-Farnesene + Diphosphate R08696 (2E,6E)-farnesyl-diphosphate lyase [(3E,6E)-alpha-farnesene-forming]; trans,trans-farnesyl-diphosphate diphosphate-lyase (alpha-farnesene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Farnesene + Diphosphate R08697 trans,trans-farnesyl-diphosphate diphosphohydrolase; (2E,6E)-farnesyl-diphosphate diphosphohydrolase; trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Farnesol + Diphosphate R08698 2-aminoacrylate aminohydrolase; Dehydroalanine + H2O <=> Pyruvate + Ammonia R08699 3'-phosphoadenylyl sulfate:2-aminoacrylate C-sulfotransferase; Dehydroalanine + 3'-Phosphoadenylyl sulfate <=> L-Cysteate + Adenosine 3',5'-bisphosphate R08700 [enzyme]-S-sulfanylcysteine:tRNA-uridine sulfurtransferase (ATP-hydrolysing); tRNA uridine + [Enzyme]-S-sulfanylcysteine + ATP <=> tRNA containing 2-thiouridine + [Enzyme]-cysteine + AMP + Diphosphate R08701 tRNA uridine 5-carboxymethylaminomethyl modification; tRNA containing 2-thiouridine + Glycine + Folinic acid + Reduced acceptor <=> tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Tetrahydrofolate + Acceptor + H2O R08702 tRNA containing 5-carboxymethylaminomethyl-2-thiouridine:oxygen oxidoreductase; tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Oxygen + H2O <=> tRNA containing 5-(aminomethyl)-2-thiouridine + Glyoxylate + Hydrogen peroxide R08704 UDP-4-dehydro-6-deoxy-glucose 3,5-epimerase; UDP-4-dehydro-6-deoxy-D-glucose <=> UDP-4-keto-rhamnose R08705 UDP-L-rhamnose:NADP+ 4-oxidoreductase; UDP-4-keto-rhamnose + NADPH + H+ <=> UDP-L-rhamnose + NADP+ R08706 UDP-N-acetyl-D-glucosaminuronate 4-epimerase; UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate <=> UDP-N-acetyl-D-galactosaminuronic acid R08707 N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase; 4-N-(N-Acetyl-D-glucosaminyl)-protein + H2O <=> N-Acetyl-beta-D-glucosaminylamine + Peptide L-aspartate R08708 CDP-4-dehydro-3,6-dideoxy-D-glucose 5-epimerase; CDP-3,6-dideoxy-D-erythro-hexos-4-ulose 5-epimerase; CDP-4-dehydro-3,6-dideoxy-D-glucose <=> CDP-4-dehydro-3,6-dideoxy-D-glucose epimer R08709 CDP-ascarylose:NAD+ 4-oxidoreductase; CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADH + H+ <=> CDP-ascarylose + NAD+ R08710 CDP-ascarylose:NADP+ 4-oxidoreductase; CDP-4-dehydro-3,6-dideoxy-D-glucose epimer + NADPH + H+ <=> CDP-ascarylose + NADP+ R08711 CDP-abequose:NADP+ 4-oxidoreductase; CDP-4-dehydro-3,6-dideoxy-D-glucose + NADPH + H+ <=> CDP-abequose + NADP+ R08712 acyl-CoA:tropine O-acyltransferase; Acyl-CoA + Tropine <=> CoA + O-Acyltropine R08713 acyl-CoA:pseudotropine O-acyltransferase; Acyl-CoA + Pseudotropine <=> CoA + O-Acylpseudotropine R08714 putrescine:pyruvate aminotransferase; Putrescine + Pyruvate <=> 4-Aminobutyraldehyde + L-Alanine R08715 chitosan exo-1,4-beta-D-glucosaminidase; chitosan glucosaminohydrolase; Chitosan(n+1) + H2O <=> Chitosan(n) + D-Glucosamine R08716 cobalt-precorrin 3 dehydrogenase; Cobalt-factor III <=> Cobalt-precorrin 3 R08717 G00309 + H2O <=> G00319 + D-Mannose R08718 G00595 + H2O <=> G00971 + D-Mannose R08721 (24S)-cholest-5-ene-3beta,7alpha,24-triol:NAD+ 3-oxidoreductase; (24S)-Cholest-5-ene-3beta,7alpha,24-triol + NAD+ <=> 7alpha,24-Dihydroxy-4-cholesten-3-one + NADH + H+ R08723 cholest-5-ene-3beta,7alpha,25-triol:NAD+ 3-oxidoreductase; Cholest-5-ene-3beta,7alpha,25-triol + NAD+ <=> 7alpha,25-Dihydroxy-4-cholesten-3-one + NADH + H+ R08724 7alpha,27-dihydroxycholesterol:NAD+ 3-oxidoreductase; 7alpha,27-Dihydroxycholesterol + NAD+ <=> 7alpha,26-Dihydroxy-4-cholesten-3-one + NADH + H+ R08725 7alpha,26-Dihydroxy-4-cholesten-3-one + 2 Oxygen + 2 NADPH + 2 H+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + 2 NADP+ + 3 H2O R08726 Cholest-5-ene-3beta,26-diol + 2 Oxygen + 2 NADPH + 2 H+ <=> 3beta-Hydroxy-5-cholestenoate + 2 NADP+ + 3 H2O R08727 3beta-hydroxy-5-cholestenoate,NADPH:oxygen oxidoreductase (7alpha-hydroxylating); 3beta-Hydroxy-5-cholestenoate + Oxygen + NADPH + H+ <=> 3beta,7alpha-Dihydroxy-5-cholestenoate + NADP+ + H2O R08728 3beta,7alpha-dihydroxy-5-cholestenoate:NAD+ 3-oxidoreductase; 3beta,7alpha-Dihydroxy-5-cholestenoate + NAD+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + NADH + H+ R08733 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + ATP + CoA <=> (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + Diphosphate R08734 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA 25-epimerase; (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA <=> (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA R08735 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24,25-oxidoreductase; (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + Acceptor <=> (24E)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor R08738 3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming); 3alpha,7alpha-Dihydroxy-5beta-cholestanate + ATP + CoA <=> (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + AMP + Diphosphate R08739 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA 25-epimerase; (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA <=> (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA R08740 (25S)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA:acceptor 24,25-oxidoreductase; (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + Acceptor <=> (24E)-3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor R08743 chenodeoxycholate:CoA ligase (AMP-forming); Chenodeoxycholoyl-CoA + AMP + Diphosphate <=> Chenodeoxycholate + CoA + ATP R08744 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:glycine N-choloyltransferase; chenodeoxycholoyl-CoA:glycine N-chenodeoxycholoyltransferase; Chenodeoxycholoyl-CoA + Glycine <=> Glycochenodeoxycholate + CoA R08745 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase; chenodeoxycholoyl-CoA:taurine N-chenodeoxycholoyltransferase; Chenodeoxycholoyl-CoA + Taurine <=> Taurochenodeoxycholate + CoA R08746 2-trans,6-trans-farnesyl-diphosphate 2-cis-trans-isomerase; trans,trans-Farnesyl diphosphate <=> 2-cis,6-trans-Farnesyl diphosphate R08747 (E)-nonaprenyl-diphosphate:isopentenyl-diphosphate nonaprenyltranstransferase; all-trans-nonaprenyl-diphosphate:isopentenyl-diphosphate nonaprenyltranstransferase; all-trans-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Decaprenyl diphosphate + Diphosphate R08748 trans,trans,cis-geranylgeranyl-diphosphate:isopentenyl-diphosphate geranylgeranylcistransferase; geranylneryl-diphosphate:isopentenyl-diphosphate geranylnerylcistransferase; trans,trans,cis-Geranylgeranyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Pentaprenyl diphosphate + Diphosphate R08749 ditrans,dicis-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenylcistransferase; di-trans,poly-cis-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Hexaprenyl diphosphate + Diphosphate R08750 ditrans,tricis-hexaprenyl-diphosphate:isopentenyl-diphosphate hexaprenylcistransferase; di-trans,poly-cis-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Heptaprenyl diphosphate + Diphosphate R08751 ditrans,tetracis-heptaprenyl-diphosphate:isopentenyl-diphosphate heptaprenylcistransferase; di-trans,poly-cis-Heptaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Octaprenyl diphosphate + Diphosphate R08752 ditrans,pentacis-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenylcistransferase; di-trans,poly-cis-Octaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Nonaprenyl diphosphate + Diphosphate R08753 ditrans,hexacis-nonaprenyl-diphosphate:isopentenyl-diphosphate nonaprenylcistransferase; di-trans,poly-cis-Nonaprenyl diphosphate + Isopentenyl diphosphate <=> di-trans,poly-cis-Decaprenyl diphosphate + Diphosphate R08754 dihydrogeranylgeranyl-diphosphate:NADP+ oxidoreductase; Geranylgeranyl diphosphate + NADPH + H+ <=> Dihydrogeranylgeranyl diphosphate + NADP+ R08755 tetrahydrogeranylgeranyl-diphosphate:NADP+ oxidoreductase; Dihydrogeranylgeranyl diphosphate + NADPH + H+ <=> Tetrahydrogeranylgeranyl diphosphate + NADP+ R08756 phytyl-diphosphate:NADP+ oxidoreductase; Tetrahydrogeranylgeranyl diphosphate + NADPH + H+ <=> Phytyl diphosphate + NADP+ R08757 hydroxylamine:ubiquinone oxidoreductase; hydroxylamine oxidase; Hydroxylamine + 2 Ubiquinone + H2O <=> Nitrite + 2 Ubiquinol R08758 3alpha,7alpha,26-Trihydroxy-5beta-cholestane <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al R08759 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al R08760 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha-Dihydroxy-5beta-cholestanate + H2O + 2 Oxidized adrenal ferredoxin R08761 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al + Oxygen + 2 H+ + 2 Reduced adrenal ferredoxin <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + H2O + 2 Oxidized adrenal ferredoxin R08762 2-aminophenol:oxygen oxidoreductase; 2 2-Aminophenol + Oxygen <=> 2 6-Iminocyclohexa-2,4-dienone + 2 H2O R08763 6-iminocyclohexa-2,4-dienone oxidoreductase (dimerizing); 2 6-Iminocyclohexa-2,4-dienone + Acceptor <=> 2-Aminophenoxazin-3-one + Reduced acceptor R08764 6-hydroxynicotinate,NADH:oxygen oxidoreductase (3-hydroxylating, decarboxylating); 6-Hydroxynicotinate + NADH + Oxygen + H+ <=> 2,5-Dihydroxypyridine + NAD+ + CO2 + H2O R08765 deoxyribocyclobutadithymine thymine-lyase; Thymine dimer <=> Two thymine residues (in DNA) R08766 3-(4-hydroxyphenyl)lactate hydro-lyase (4-coumarate-forming); (R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + H2O R08767 p-Coumaroyl-CoA + CoA + NAD+ + H2O <=> 4-Hydroxybenzoyl-CoA + Acetyl-CoA + NADH + H+ R08768 2-(all-trans-polyprenyl)phenol,NADPH:oxygen oxidoreductase (6-hydroxylating); 2-Polyprenylphenol + NADPH + H+ + Oxygen <=> 2-Polyprenyl-6-hydroxyphenol + NADP+ + H2O R08769 S-adenosyl-L-methionine:2-polyprenyl-6-hydroxyphenol 6-O-methyltransferase; S-adenosyl-L-methionine:3-(all-trans-polyprenyl)benzene-1,2-diol 2-O-methyltransferase; 2-Polyprenyl-6-hydroxyphenol + S-Adenosyl-L-methionine <=> 2-Polyprenyl-6-methoxyphenol + S-Adenosyl-L-homocysteine R08770 4-Hydroxy-3-polyprenylbenzoate + Oxygen <=> 3,4-Dihydroxy-5-polyprenylbenzoate + H2O R08771 S-adenosyl-L-methionine:3,4-dihydroxy-5-polyprenylbenzoate 3-O-methyltransferase; 3,4-Dihydroxy-5-polyprenylbenzoate + S-Adenosyl-L-methionine <=> 3-Methoxy-4-hydroxy-5-polyprenylbenzoate + S-Adenosyl-L-homocysteine R08772 3-polyprenyl-4-hydroxy-5-methoxybenzoate carboxy-lyase (2-polyprenyl-6-methoxyphenol-forming); 3-Methoxy-4-hydroxy-5-polyprenylbenzoate <=> 2-Polyprenyl-6-methoxyphenol + CO2 R08776 glycyl-tRNA:undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine N6-glycyltransferase; Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine <=> tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine R08777 glycyl-tRNA:undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine glycyltransferase; 2 Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)-D-alanyl-D-alanine <=> 2 tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine R08778 glycyl-tRNA:undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine glycyltransferase; 2 Glycyl-tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine <=> 2 tRNA(Gly) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-(glycyl)5-D-alanyl-D-alanine R08779 L-alanyl-tRNA:undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase; L-Alanyl-tRNA + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> tRNA(Ala) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine R08780 L-alanyl-tRNA:undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine alanyltransferase; L-Alanyl-tRNA + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl)-D-alanyl-D-alanine <=> tRNA(Ala) + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-(L-alanyl-L-alanyl)-D-alanyl-D-alanine R08782 all-trans-nonaprenyl-diphosphate:homogentisate nonaprenyltransferase (decarboxylating); Homogentisate + all-trans-Nonaprenyl diphosphate <=> 2-Methyl-6-solanyl-1,4-benzoquinol + Diphosphate + CO2 R08784 1,8-cineole,[reduced flavodoxin]:oxygen oxidoreductase (2-endo-hydroxylating); 1,8-Cineole + Reduced flavodoxin + Oxygen <=> 6-endo-Hydroxycineole + Oxidized flavodoxin + H2O R08785 geraniol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); Geraniol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Hydroxygeraniol + [Oxidized NADPH---hemoprotein reductase] + H2O R08787 S-adenosyl-L-methionine:(S)-reticuline 7-O-methyltransferase; (S)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine R08788 S-adenosyl-L-methionine:(R)-reticuline 7-O-methyltransferase; (R)-Reticuline + S-Adenosyl-L-methionine <=> Laudanine + S-Adenosyl-L-homocysteine R08789 S-adenosyl-L-methionine:(S)-canadine N-methyltransferase; S-Adenosyl-L-methionine + (S)-Canadine <=> S-Adenosyl-L-homocysteine + (S)-cis-N-Methylcanadine R08790 (S)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling; (S)-corytuberine-forming); (S)-Reticuline + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Corytuberine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08791 S-adenosyl-L-methionine:(S)-corytuberine N-methyltransferase; (S)-Corytuberine + S-Adenosyl-L-methionine <=> Magnoflorine + S-Adenosyl-L-homocysteine R08792 chain-elongation cycle; Amino acid <=> Homoamino acid R08794 S-Adenosyl-L-methionine + (S)-6-O-Methylnorlaudanosoline <=> S-Adenosyl-L-homocysteine + 3'-Hydroxy-N-methyl-(S)-coclaurine R08795 tetrahydropalmatine:oxygen oxidoreductase; Tetrahydropalmatine + 2 Oxygen + H+ <=> Palmatine + 2 Hydrogen peroxide R08796 p-Coumaroyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-(4-Hydroxyphenyl)-1-decene-3,5-dione + 3 CoA + 2 CO2 R08797 Feruloyl-CoA + Malonyl-CoA + Hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2 R08798 1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone R08799 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone R08800 1-Dehydro-[6]-gingerdione <=> [6]-Gingerol R08801 1-(4-Hydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione R08802 5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone R08803 S-adenosyl-L-methionine:1-(3,4-dihydroxyphenyl)-1-decene-3,5-dione O-methyltransferase; 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione + S-Adenosyl-L-methionine <=> 1-Dehydro-[6]-gingerdione + S-Adenosyl-L-homocysteine R08804 S-adenosyl-L-methionine:1-(3,4-dihydroxyphenyl)-5-hydroxy-3-decanone O-methyltransferase; 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone + S-Adenosyl-L-methionine <=> [6]-Gingerol + S-Adenosyl-L-homocysteine R08805 p-coumaroyl-CoA:malonyl-CoA C-coumaroyltransferase (decarboxylating); p-Coumaroyl-CoA + Malonyl-CoA <=> p-Coumaroyl-diketide-CoA + CoA + CO2 R08806 feruloyl-CoA:malonyl-CoA C-feruloyltransferase (decarboxylating); Feruloyl-CoA + Malonyl-CoA <=> Feruloyl-diketide-CoA + CoA + CO2 R08807 p-coumaroyl-CoA:p-coumaroyl-diketide-CoA C-coumaroyltransferase (thioester-hydrolysing and decarboxylating); p-Coumaroyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Bisdemethoxycurcumin + 2 CoA + CO2 R08808 feruloyl-CoA:p-coumaroyl-diketide-CoA C-feruloyltransferase (thioester-hydrolysing and decarboxylating); p-Coumaroyl-diketide-CoA + Feruloyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2 R08809 p-coumaroyl-CoA:feruloyl-diketide-CoA C-coumaroyltransferase (thioester-hydrolysing and decarboxylating); Feruloyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2 R08810 feruloyl-CoA:feruloylacetyl-CoA feruloyltransferase (curcumin-forming); Feruloyl-diketide-CoA + Feruloyl-CoA + H2O <=> Curcumin + 2 CoA + CO2 R08811 Bisdemethoxycurcumin <=> Demethoxycurcumin R08812 Demethoxycurcumin <=> Curcumin R08813 UDP-glucose:curcumin glucosyltransferase; Curcumin + UDP-glucose <=> Curcumin monoglucoside + UDP R08814 UDP-glucose:curcumin-monoglucoside glucosyltransferase; Curcumin monoglucoside + UDP-glucose <=> Curcumin diglucoside + UDP R08815 cinnamoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating); Cinnamoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> p-Coumaroyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O R08816 UDP-glucose:2,3-dihydro-5,6-dihydroxyindole-2-carboxylate 5-O-beta-D-glucosyltransferase; 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + UDP-glucose <=> cyclo-Dopa 5-O-glucoside + UDP R08817 UDP-glucuronate:cyclo-DOPA-5-O-glucoside 2'-O-beta-D-glucuronosyltransferase; cyclo-Dopa 5-O-glucoside + UDP-glucuronate <=> cyclo-Dopa-glucuronylglucoside + UDP R08818 cyclo-Dopa-glucuronylglucoside + Betalamic acid <=> Amaranthin + H2O R08819 1-O-feruloyl-beta-D-glucose:amaranthin feruloyltransferase; Amaranthin + 1-O-Feruloyl-beta-D-glucose <=> Celosianin II + D-Glucose R08820 cyclo-Dopa 5-O-glucoside + Betalamic acid <=> Betanin + H2O R08821 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + Betalamic acid <=> Betanidin + H2O R08822 UDP-glucose:betanidin 5-O-beta-D-glucosyltransferase; Betanidin + UDP-glucose <=> Betanin + UDP R08823 1-O-feruloyl-beta-D-glucose:betanin feruloyltransferase; Betanin + 1-O-Feruloyl-beta-D-glucose <=> Lampranthin II + D-Glucose R08824 UDP-glucuronate:betanin beta-D-glucuronosyltransferase; Betanin + UDP-glucuronate <=> Amaranthin + UDP R08825 L-Tyrosine + Betalamic acid <=> Portulacaxanthin II + H2O R08826 portulacaxanthin-II,dopaxanthin:oxygen oxidoreductase; Portulacaxanthin II + Oxygen + Dopaxanthin <=> Dopaxanthin + H2O + Dopaxanthin quinone R08827 3,4-Dihydroxy-L-phenylalanine + Betalamic acid <=> Dopaxanthin + H2O R08828 dopaxanthin:oxygen oxidoreductase; 2 Dopaxanthin + Oxygen <=> 2 Dopaxanthin quinone + 2 H2O R08829 Dopaxanthin quinone <=> Betanidin R08830 UDP-glucose:betanidin 6-O-beta-D-glucosyltransferase; Betanidin + UDP-glucose <=> Gomphrenin-I + UDP R08831 3-Methoxytyramine + Betalamic acid <=> 3-Methoxytyramine-betaxanthin + H2O R08832 dopamine:oxygen oxidoreductase; 2 Dopamine + Oxygen <=> 2 Dopamine quinone + 2 H2O R08833 Dopamine quinone <=> 2-Descarboxy-cyclo-dopa R08834 2-Descarboxy-cyclo-dopa + Betalamic acid <=> 2-Descarboxy-betanidin + H2O R08835 Dopamine + Betalamic acid <=> Miraxanthin-V + H2O R08836 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (decyclizing); 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 4,5-seco-Dopa R08837 4,5-seco-Dopa <=> Betalamic acid + H2O R08838 benzoate,NADPH:oxygen oxidoreductase (2-hydroxylating); Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O R08839 UDP-glucose:ferulate D-glucosyltransferase; UDP-glucose + Ferulate <=> 1-O-Feruloyl-beta-D-glucose + UDP R08840 teasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, 7-oxateasterone-forming); Teasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Oxateasterone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08841 typhasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, 7-oxatyphasterol-forming); Typhasterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Oxatyphasterol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08842 7-Oxateasterone <=> 7-Oxatyphasterol R08843 1-Guanidino-1-deoxy-scyllo-inositol <=> 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol R08844 ATP:1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphotransferase; ATP + 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol <=> ADP + N1-Amidinostreptamine 6-phosphate R08845 UTP:monosaccharide-1-phosphate uridylyltransferase; UTP + alpha-D-Aldose 1-phosphate <=> Diphosphate + UDP-sugar R08846 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming); 3,4-Dihydroxy-L-phenylalanine + NADH + H+ <=> 3,4-Dihydroxyphenylpropanoate + NAD+ + Ammonia R08847 3,4-Dihydroxyphenylpropanoate <=> (R)-3-(3,4-Dihydroxyphenyl)lactate R08848 Dopaquinone + L-Cysteine <=> Cysteinyldopa R08849 Cysteinyldopa <=> Phaeomelanin R08850 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine carboxypeptidase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + H2O <=> UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + D-Alanine R08851 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5S-hydroxylating); (+)-epi-Isozizaene + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> (5S)-Albaflavenol + 2 Oxidized [2Fe-2S] ferredoxin + H2O R08852 (5S)-albaflavenol,reduced-ferredoxin:oxygen oxidoreductase; (5S)-Albaflavenol + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> Albaflavenone + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O R08853 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5R-hydroxylating); (+)-epi-Isozizaene + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> (5R)-Albaflavenol + 2 Oxidized [2Fe-2S] ferredoxin + H2O R08854 (5R)-albaflavenol,reduced-ferredoxin:oxygen oxidoreductase; (5R)-Albaflavenol + 2 Reduced [2Fe-2S] ferredoxin + 2 H+ + Oxygen <=> Albaflavenone + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O R08855 undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine:L-glutamine amido-ligase (ADP-forming); Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-Glutamine + ATP + H2O <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + L-Glutamate + ADP + Orthophosphate R08856 UDP-N-acetyl-D-glucosamine:undecaprenyl-phosphate N-acetyl-D-glucosamine phosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> N-Acetyl-D-glucosaminyldiphosphoundecaprenol + UMP R08857 dTDP-L-rhamnose:alpha-D-galactosyl-diphosphoundecaprenol L-rhamnosyltransferase; alpha-D-Galactosyl-diphosphoundecaprenol + dTDP-L-rhamnose <=> alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + dTDP R08858 GDP-D-mannose:alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol D-mannosyltransferase; alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + GDP-mannose <=> alpha-D-Mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol + GDP R08859 UDP-glucose:limonoate-A-ring-lactone glucosyltransferase; Limonoate A-ring-lactone + UDP-glucose <=> Glucosyl-limonin + UDP R08861 Phosphonoacetaldehyde + NADPH + H+ <=> 2-Hydroxyethylphosphonate + NADP+ R08862 methylcobalamin:2-hydroxyethylphosphonate C-methyltransferase; 2-Hydroxyethylphosphonate + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> (S)-2-Hydroxypropylphosphonate + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine R08863 (S)-2-hydroxypropylphosphonate,NADH:oxygen epoxidase; (S)-2-Hydroxypropylphosphonate + Hydrogen peroxide <=> Fosfomycin + 2 H2O R08864 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming); 2-Hydroxyethylphosphonate + Oxygen <=> Hydroxymethylphosphonate + Formate R08865 Hydroxymethylphosphonate <=> Formylphosphonate R08866 Formylphosphonate <=> Phosphonoformate R08867 CTP:phosphonoformate cytidylyltransferase; Phosphonoformate + CTP <=> Phosphonoformyl-CMP + Diphosphate R08868 1-carboxyvinyl carboxyphosphonate phosphorylmutase; 1-Carboxyvinyl carboxyphosphonate <=> Carboxyphosphonopyruvate R08869 carboxyphosphonopyruvate carboxy-lyase; Carboxyphosphonopyruvate <=> 3-(Hydrohydroxyphosphoryl)pyruvate + CO2 R08870 acetyl-CoA:phosphinopyruvate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming); 3-(Hydrohydroxyphosphoryl)pyruvate + Acetyl-CoA + H2O <=> 2-Phosphinomethylmalate + CoA R08871 acetyl-CoA:demethylphosphinothricin N-acetyltransferase; Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA R08872 N-acetyldemethylphosphinothricin:L-alanine:L-alanine ligase (AMP-forming); N-Acetyldemethylphosphinothricin + 2 L-Alanine + 3 ATP + H2O <=> N-Acetyldemethylphosphinothricin tripeptide + 3 AMP + 3 Diphosphate R08873 methylcobalamin:N-acetyldemethylphosphinothricin P-methyltransferase; N-Acetyldemethylphosphinothricin + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> N-Acetylphosphinothricin + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine R08874 N-acetylphosphinothricin amidohydrolase; N-Acetylphosphinothricin + H2O <=> L-Phosphinothricin + Acetate R08875 methylcobalamin:N-acetyldemethylphosphinothricin-tripeptide P-methyltransferase; N-Acetyldemethylphosphinothricin tripeptide + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> N-Acetylbialaphos + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine R08876 N-acetylbialaphos amidohydrolase; N-Acetylbialaphos + H2O <=> Bialaphos + Acetate R08877 Deamino-alpha-keto-demethylphosphinothricin <=> Demethylphosphinothricin R08878 2-dehydro-L-idonate:NADP+ 5-oxidoreductase; 2-Dehydro-L-idonate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+ R08879 5-dehydro-D-gluconate:NADP+ 2-oxidoreductase; 5-Dehydro-D-gluconate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+ R08880 L-idonate:NADP+ 2-oxidoreductase; L-Idonate + NADP+ <=> 2-Dehydro-L-idonate + NADPH + H+ R08881 (R)-2-(Phosphonomethyl)malate <=> 2-Oxo-4-phosphonobutanoate R08882 2-Oxo-4-phosphonobutanoate <=> FR 900098 R08883 Phosphonoacetaldehyde <=> Rhizocticin B R08884 Phosphonoacetaldehyde <=> Rhizocticin A R08885 Phosphonoacetaldehyde <=> Rhizocticin C R08886 Phosphonoacetaldehyde <=> Rhizocticin D R08887 Phosphonoformyl-CMP + 3-Phospho-D-glycerate <=> 1-Carboxyvinyl carboxyphosphonate + CMP + Orthophosphate R08888 3-Phosphinomethylmalate <=> Deamino-alpha-keto-demethylphosphinothricin R08889 8'-apo-beta-carotenol:O2 oxidoreductase; 8'-apo-beta-Carotenol + Oxygen <=> 14'-apo-beta-Carotenal + 7-Hydroxy-6-methylhepta-3,5-dienal R08890 L-glutamine:2-deoxy-scyllo-inosose aminotransferase; 2-Deoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate R08891 L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase; 3-Amino-2,3-dideoxy-scyllo-inosose + L-Glutamine <=> 2-Deoxystreptamine + 2-Oxoglutaramate R08892 2-deoxy-scyllo-inosamine:NAD+ oxidoreductase; 2-Deoxy-scyllo-inosamine + NAD+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADH + H+ R08893 2-deoxy-scyllo-inosamine:S-adenosyl-L-methionine 1-oxidoreductase; 2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine <=> 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine R08894 UDP-N-acetyl-alpha-D-glucosamine:2-deoxystreptamine N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 2-Deoxystreptamine <=> UDP + 2'-N-Acetylparomamine R08895 2'-N-acetylparomamine hydrolase (acetate-forming); 2'-N-Acetylparomamine + H2O <=> Paromamine + Acetate R08896 paromamine:oxygen 6'-oxidoreductase; Paromamine + Oxygen <=> 6'-Dehydro-6'-oxoparomamine + Hydrogen peroxide R08897 neamine:2-oxoglutarate aminotransferase; Neamine + 2-Oxoglutarate <=> 6'-Dehydro-6'-oxoparomamine + L-Glutamate R08898 5-phospho-alpha-D-ribose 1-diphosphate:neamine phosphoribosyltransferase; 5''-phosphoribostamycin:diphosphate phospho-alpha-D-ribosyltransferase; 5-Phospho-alpha-D-ribose 1-diphosphate + Neamine <=> Diphosphate + 5''-Phosphoribostamycin R08899 5''-phosphoribostamycin phosphohydrolase; 5''-Phosphoribostamycin + H2O <=> Ribostamycin + Orthophosphate R08900 UDP-N-acetyl-alpha-D-glucosamine:ribostamycin N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Ribostamycin <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C R08901 2'''-acetyl-6'''-hydroxyneomycin-C hydrolase (acetate-forming); 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate R08902 6'''-deamino-6'''-hydroxyneomycin-C:oxygen 6'''-oxidoreductase; 6'''-Deamino-6'''-hydroxyneomycin C + Oxygen <=> 6'''-Deamino-6'''-oxoneomycin C + Hydrogen peroxide R08903 2-oxoglutarate:neomycin-C aminotransferase; Neomycin C + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoneomycin C + L-Glutamate R08904 neomycin-C 5'''-epimerase; Neomycin C <=> Neomycin B R08905 L-glutamate:[acyl-carrier protein] ligase (ADP-forming); ATP + L-Glutamate + Acyl-carrier protein <=> ADP + Orthophosphate + gamma-L-Glutamyl-[acp] R08906 L-glutamate:4-aminobutyryl-[acp] ligase (ADP-forming); ATP + L-Glutamate + 4-Aminobutyryl-[acp] <=> ADP + Orthophosphate + 4-(gamma-L-Glutamylamino)butanoyl-[acp] R08907 gamma-L-glutamyl-[acp] carboxy-lyase (4-aminobutyryl-[acp]-forming); gamma-L-Glutamyl-[acp] <=> 4-Aminobutyryl-[acp] + CO2 R08908 4-(gamma-L-glutamylamino)butanoyl-[acp],reduced-FMN:oxygen oxidoreductase; 4-(gamma-L-Glutamylamino)butanoyl-[acp] + Reduced FMN + Oxygen <=> 4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + FMN + H2O R08909 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[acp]:ribostamycin 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase; 4-(gamma-L-Glutamylamino)-(2S)-2-hydroxybutanoyl-[acp] + Ribostamycin <=> Acyl-carrier protein + gamma-L-Glutamyl-butirosin B R08910 gamma-L-glutamyl-butirosin-B gamma-glutamyl cyclotransferase (5-oxoproline-forming); gamma-L-Glutamyl-butirosin B <=> Butirosin B + 5-Oxoproline R08911 Butirosin B <=> Butirosin A R08912 flaviolin,reduced ferredoxin:oxygen oxidoreductase; 2 Flaviolin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 3,3'-Biflaviolin + 2 Oxidized ferredoxin + 2 H2O R08913 flaviolin,reduced ferredoxin:oxygen oxidoreductase; 2 Flaviolin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 3,8'-Biflaviolin + 2 Oxidized ferredoxin + 2 H2O R08914 7(1)-hydroxychlorophyllide-a:NAD+ oxidoreductase; 7(1)-Hydroxychlorophyllide a + NAD+ <=> Chlorophyllide b + NADH + H+ R08915 7(1)-hydroxychlorophyllide-a:NADP+ oxidoreductase; 7(1)-Hydroxychlorophyllide a + NADP+ <=> Chlorophyllide b + NADPH + H+ R08916 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide:NAD+ oxidoreductase; 3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD+ <=> Momilactone A + NADH + H+ R08917 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide:NADP+ oxidoreductase; 3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> Momilactone A + NADPH + H+ R08918 menth-8-en-2-ol:NAD+ oxidoreductase; 1,6-Dihydrocarveol + NAD+ <=> Dihydrocarvone + NADH + H+ R08919 menth-8-ene-1,2-diol:NAD+ oxidoreductase; p-Menth-8-ene-1,2-diol + NAD+ <=> 1-Hydroxy-p-menth-8-en-2-one + NADH + H+ R08920 3,4-dihydroxy-L-phenylalanine:oxygen oxidoreductase (deaminating); 2 3,4-Dihydroxy-L-phenylalanine + Oxygen <=> 2 3-(3,4-Dihydroxyphenyl)pyruvate + 2 Ammonia R08921 pheophorbide-a,ferredoxin:oxygen oxidoreductase (biladiene-forming); Pheophorbide a + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Red chlorophyll catabolite + 2 Oxidized ferredoxin R08922 sophoraflavanone-B,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating); Sophoraflavanone B + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Leachianone G + [Oxidized NADPH---hemoprotein reductase] + H2O R08923 (+)-pulegone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9-hydroxylating); Pulegone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-Menthofuran + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R08924 butanoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + HCO3- + Butanoyl-CoA + H+ <=> ADP + Orthophosphate + (2S)-Ethylmalonyl-CoA R08925 (-)-menthone,NADPH:oxygen oxidoreductase; (-)-Menthone + NADPH + H+ + Oxygen <=> (4R,7S)-7-Isopropyl-4-methyloxepan-2-one + NADP+ + H2O R08926 L-fucose:NAD+ 1-oxidoreductase; L-Fucose + NAD+ <=> L-Fucono-1,5-lactone + NADH + H+ R08927 dTDP-3,4-dioxo-2,6-dideoxy-D-glucose <=> dTDP-3-oxo-2,6-dideoxy-D-glucose R08928 dTDP-3-oxo-2,6-dideoxy-D-glucose <=> dTDP-2,6-dideoxy-D-kanosamine R08929 dTDP-2,6-dideoxy-D-kanosamine <=> dTDP-D-angolosamine R08930 dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose hydro-lyase (dTDP-2,3,6-trideoxy-alpha-D-hexopyranose-forming); dTDP-4-oxo-2,6-dideoxy-D-glucose + Reduced ferredoxin + H+ <=> dTDP-4-oxo-2,3,6-trideoxy-D-glucose + H2O + Oxidized ferredoxin R08931 dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose:2-oxoglutarate aminotransferase; dTDP-4-oxo-2,3,6-trideoxy-D-glucose + L-Glutamate <=> dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2-Oxoglutarate R08932 S-adenosyl-L-methionine:dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase; dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2 S-Adenosyl-L-methionine <=> dTDP-D-forosamine + 2 S-Adenosyl-L-homocysteine R08933 S-adenosyl-L-methionine:dTDP-4-oxo-2,6-dideoxy-D-allose 3-C-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose R08934 dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose 5-epimerase; dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose R08935 dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase (3,5-epimerizing); dTDP-L-rhamnose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+ R08936 malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxytransferase; Malonyl-[acyl-carrier protein] + Biotinyl-[protein] <=> Acetyl-[acyl-carrier protein] + Carboxybiotinyl-[protein] R08937 carbamoyl-phosphate:N2-succinyl-L-ornithine carbamoyltransferase; Carbamoyl phosphate + N2-Succinyl-L-ornithine <=> Orthophosphate + N-Succinyl-L-citrulline R08938 acetyl-CoA:phosphinothricin N-acetyltransferase; Acetyl-CoA + L-Phosphinothricin <=> CoA + N-Acetylphosphinothricin R08939 butyryl-[acyl-carrier protein]:S-adenosyl-L-methionine butyryltranserase (lactone-forming, methylthioadenosine-releasing); Butyryl-[acp] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Butyryl-L-homoserine lactone R08940 acyl-[acyl-carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing); Acyl-[acyl-carrier protein] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Acyl-L-homoserine lactone R08941 cholesterol-sulfate sulfohydrolase; steryl-sulfate sulfohydrolase; Cholesterol + Sulfate <=> Cholesterol sulfate + H2O R08942 pregnenolone-sulfate sulfohydrolase; steryl-sulfate sulfohydrolase; Pregnenolone + Sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + H2O R08943 pregnenolone,NADPH:oxygen oxidoreductase (7alpha-hydroxylating); Pregnenolone + NADPH + H+ + Oxygen <=> 7alpha-Hydroxypregnenolone + NADP+ + H2O R08944 acetyl-[acyl-carrier-protein]: malonate S-[acyl-carrier-protein]transferase; Acetyl-[acyl-carrier protein] + Malonate <=> Malonyl-[acyl-carrier protein] + Acetate R08945 11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase; 11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+ R08946 ADP-glucose: D-glucose 1-alpha-D-glucosyltransferase; ADP-glucose + D-Glucose <=> alpha,alpha-Trehalose + ADP R08947 GDP-mannose: D-fructose-6-phosphate 2-alpha-D-mannosyltransferase; GDP-mannose + D-Fructose 6-phosphate <=> GDP + beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate R08948 dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming); 2 Dimethylallyl diphosphate <=> Diphosphate + Chrysanthemyl diphosphate R08949 11-deoxycorticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta,18-hydroxylating); 11-Deoxycorticosterone + 3 Reduced adrenal ferredoxin + 3 Oxygen <=> Aldosterone + 3 Oxidized adrenal ferredoxin + 4 H2O R08950 dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming); 2 Dimethylallyl diphosphate <=> Diphosphate + Lavandulyl diphosphate R08951 dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase; Dimethylallyl diphosphate + Naringenin <=> Diphosphate + Sophoraflavanone B R08952 dimethylallyl-diphosphate:leachianone-G 2''-dimethylallyltransferase; Dimethylallyl diphosphate + Leachianone G <=> Diphosphate + Sophoraflavanone G R08953 Aldosterone <=> Aldosterone hemiacetal R08954 5alpha-dihydrodeoxycorticosterone:NADP+ delta4-oxidoreductase; 11-Deoxycorticosterone + NADPH + H+ <=> 5alpha-Dihydrodeoxycorticosterone + NADP+ R08955 3alpha,21-dihydroxy-5alpha-pregnan-20-one:NADP+ 3-oxidoreductase (A-specific); 5alpha-Dihydrodeoxycorticosterone + NADPH + H+ <=> Allotetrahydrodeoxycorticosterone + NADP+ R08956 (2S)-2-amino-4-deoxychorismate:L-glutamate aminotransferase; 2-Amino-2-deoxyisochorismate + L-Glutamate <=> Chorismate + L-Glutamine R08957 3alpha-hydroxy-5alpha-pregnan-20-one:NADP+ 3-oxidoreductase (A-specific); 5alpha-Pregnane-3,20-dione + NADPH + H+ <=> Allopregnanolone + NADP+ R08958 5alpha-pregnan-20alpha-ol-3-one:NADP+ 20-oxidoreductase; 5alpha-Pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-Pregnane-3,20-dione + NADPH + H+ R08959 5alpha-pregnane-3alpha,20alpha-diol:NADP+ 20-oxidoreductase; 5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+ R08960 5alpha-pregnane-3alpha,20alpha-diol:NADP+ oxidoreductase (A-specific); 5alpha-Pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5alpha-Pregnane-3alpha,20alpha-diol + NADP+ R08961 dehydroepiandrosterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating); Dehydroepiandrosterone + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 7alpha-Hydroxydehydroepiandrosterone + [Oxidized NADPH---hemoprotein reductase] + H2O R08962 ATP:N-acetyl-D-hexosamine 1-phosphotransferase; ATP + N-Acetyl-D-hexosamine <=> ADP + N-Acetyl-alpha-D-hexosamine 1-phosphate R08963 androstan-3alpha,17beta-diol:NADP+ oxidoreductase; Androstan-3alpha,17beta-diol + NADP+ <=> Dihydrotestosterone + NADPH + H+ R08964 ATP:1D-myo-inositol-5-diphosphate-pentakisphosphate phosphotransferase; ATP + 5-PP-InsP5 <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate R08965 5,6-dihydroxyindole-2-carboxylate:oxygen oxidoreductase; 2 5,6-Dihydroxyindole-2-carboxylate + Oxygen <=> 2 5,6-Indolequinone-2-carboxylic acid + 2 H2O R08966 CTP:2,3-bis-(O-geranylgeranyl)-sn-glycerol-1-phosphate cytidylyltransferase; CTP + 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol R08967 ATP:N-acetyl-D-galactosamine 1-phosphotransferase; N-Acetyl-D-galactosamine + ATP <=> N-Acetyl-alpha-D-galactosamine 1-phosphate + ADP R08968 ATP:N-acetyl-D-glucosamine 1-phosphotransferase; N-Acetyl-D-glucosamine + ATP <=> N-Acetyl-alpha-D-glucosamine 1-phosphate + ADP R08969 ceramide:phosphatidylcholine cholinephosphotransferase; N-Acylsphingosine + Phosphatidylcholine <=> Sphingomyelin + 1,2-Diacyl-sn-glycerol R08970 N-acyl-L-homoserine-lactone lactonohydrolase; N-Acyl-L-homoserine lactone + H2O <=> N-Acyl-L-homoserine R08972 (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside:oxygen oxidoreductase (7-hydroxylating); DIBOA-glucoside + 2-Oxoglutarate + Oxygen <=> TRIBOA-glucoside + Succinate + CO2 R08973 S-adenosyl-L-methionine:TRIBOA-glucoside 7-O-methyltransferase; S-Adenosyl-L-methionine + TRIBOA-glucoside <=> S-Adenosyl-L-homocysteine + DIMBOA-glucoside R08974 pheophorbide-a hydrolase (decarboxylating); Pheophorbide a + H2O <=> Pyropheophorbide a + Methanol + CO2 R08975 pheophorbide-a hydrolase; Pheophorbide a + H2O <=> C-13(2)-Carboxypyropheophorbide a + Methanol R08976 C-13(2)-Carboxypyropheophorbide a <=> Pyropheophorbide a + CO2 R08977 3'-phosphoadenylyl-sulfate:cholesterol sulfotransferase; Cholesterol + 3'-Phosphoadenylyl sulfate <=> Cholesterol sulfate + Adenosine 3',5'-bisphosphate R08978 3'-phosphoadenylyl-sulfate:pregnenolone sulfotransferase; Pregnenolone + 3'-Phosphoadenylyl sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + Adenosine 3',5'-bisphosphate R08979 7-isopropyl-4-methyloxepan-2-one lactonohydrolase; 7-Isopropyl-4-methyloxepan-2-one + H2O <=> 6-Hydroxy-3,7-dimethyloctanoate R08980 11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase; 11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+ R08981 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate R08982 beta-D-fructofuranosyl-alpha-D-mannopyranoside-6F-phosphate phosphohydrolase; beta-D-Fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate + H2O <=> beta-D-Fructofuranosyl-alpha-D-mannopyranoside + Orthophosphate R08983 3 p-Coumaroyl-CoA + Spermidine <=> N1,N5,N10-Tricoumaroyl spermidine + 3 CoA R08984 N1,N5,N10-Tricoumaroyl spermidine <=> N1,N5,N10-Tricaffeoyl spermidine R08985 N1,N5,N10-Tricaffeoyl spermidine <=> N1,N5,N10-Triferuloyl spermidine R08986 N1,N5,N10-Triferuloyl spermidine <=> N1,N5,N10-Tri(hydroxyferuloyl) spermidine R08987 N1,N5,N10-Tri(hydroxyferuloyl) spermidine + S-Adenosyl-L-methionine <=> N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl spermidine + S-Adenosyl-L-homocysteine R08988 beta-Carotene <=> Strigolactone ABC-rings R08989 Strigolactone ABC-rings <=> 5-Deoxystrigol R08990 5-Deoxystrigol <=> Strigol R08991 cyclic bis(3->5')diguanylate 3-guanylylhydrolase; 3',5'-Cyclic diGMP + H2O <=> 5'-Phosphoguanylyl(3'->5')guanosine R08992 geranylgeranyl-diphosphate diphosphohydrolase (sclareol-forming); Geranylgeranyl diphosphate + 2 H2O <=> Sclareol + Diphosphate R08993 geranyl-diphosphate diphosphohydrolase; Geranylgeranyl diphosphate + H2O <=> Geranylgeraniol + Diphosphate R08994 11-Dehydrocorticosterone <=> 21-Hydroxy-5beta-pregnane-3,11,20-trione R08995 Cortisol <=> 11beta-Hydroxyandrost-4-ene-3,17-dione R08996 dimethylallyl-diphosphate:umbelliferone 6-dimethylallyltransferase; Umbelliferone + Dimethylallyl diphosphate <=> Demethylsuberosin + Diphosphate R08997 demethylsuberosin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Demethylsuberosin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Marmesin + [Oxidized NADPH---hemoprotein reductase] + H2O R08998 Psoralen + NADPH + Oxygen + H+ <=> Bergaptol + NADP+ + H2O R08999 Psoralen + NADPH + Oxygen + H+ <=> Xanthotoxol + NADP+ + H2O R09000 Umbelliferone + Dimethylallyl diphosphate <=> Osthenol + Diphosphate R09002 (+)-columbianetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (+)-Columbianetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Angelicin + [Oxidized NADPH---hemoprotein reductase] + Acetone + 2 H2O R09009 UDP-L-arabinopyranose furanomutase; UDP-L-arabinose <=> UDP-L-arabinofuranose R09016 Umbelliferone <=> Esculetin R09030 D-allose-6-phosphate aldose-ketose-isomerase; D-Allose 6-phosphate <=> D-Allulose 6-phosphate R09031 D-Allulose 6-phosphate <=> D-Fructose 6-phosphate R09032 primary fluorescent chlorophyll catabolite:ferredoxin oxidoreductase; Primary fluorescent chlorophyll catabolite + 2 Oxidized ferredoxin <=> Red chlorophyll catabolite + 2 Reduced ferredoxin + 2 H+ R09033 chlorophyllide magnesium-lyase (pheophorbide-forming); Chlorophyllide + 2 H+ <=> Pheophorbide a + Magnesium cation R09034 acyl-CoA:1-acyl-sn-glycero-3-phosphoinositol O-acyltransferase; Acyl-CoA + 1-Acylglycerophosphoinositol <=> CoA + 1-Phosphatidyl-D-myo-inositol R09035 acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase; Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine R09036 acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase; Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol R09037 Acyl-CoA + Monolysocardiolipin <=> CoA + Cardiolipin R09038 cardiolipin acylhydrolase; Cardiolipin + H2O <=> Monolysocardiolipin + Fatty acid R09039 4-(beta-D-glucosyloxy)benzoate glucohydrolase; 4-(beta-D-Glucosyloxy)benzoate + H2O <=> 4-Hydroxybenzoate + D-Glucose R09040 geranyl-diphosphate:4-hydroxybenzoate geranyltransferase; 4-Hydroxybenzoate + Geranyl diphosphate <=> Geranyl-hydroxybenzoate + Diphosphate R09041 Geranyl-hydroxybenzoate <=> Geranylhydroquinone R09042 geranylhydroquinone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3''-hydroxylating); Geranylhydroquinone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3''-Hydroxy-geranylhydroquinone + [Oxidized NADPH---hemoprotein reductase] + H2O R09043 3''-Hydroxy-geranylhydroquinone <=> Deoxyshikonin R09044 Deoxyshikonin <=> Shikonin R09045 Geranylhydroquinone <=> Dihydroshikonofuran R09046 Dihydroshikonofuran <=> Dihydroechinofuran R09047 ATP:gentamicin-A 2''-adenylyltransferase; ATP + Gentamicin A <=> Diphosphate + 2''-Adenylylgentamicin A R09048 3 Cadaverine + 4 Pyruvate <=> 17-Oxosparteine + 4 L-Alanine + 3 H2O R09049 17-Oxosparteine <=> Lupanine R09050 Lupanine <=> 13-Hydroxylupanine R09051 3,6-Dihydronicotinic acid <=> 3,6-Dihydropyridine R09052 Piperideine <=> Piperidine R09053 3-vinylbacteriochlorophyllide a:ferredoxin 7,8-oxidoreductase; Chlorophyllide + 2 Reduced ferredoxin + ATP + H2O + 2 H+ <=> 3-Vinylbacteriochlorophyllide a + 2 Oxidized ferredoxin + ADP + Orthophosphate R09054 3-hydroxyethylbacteriochlorophyllide-a hydro-lyase (3-vinylbacteriochlorophyllide-a-forming); 3-Vinylbacteriochlorophyllide a + H2O <=> 3-Hydroxyethylbacteriochlorophyllide a R09055 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide-a:NAD+ oxidoreductase (bacteriochlorophyllide a-forming); 3-Hydroxyethylbacteriochlorophyllide a + NAD+ <=> Bacteriochlorophyllide a + NADH + H+ R09056 Bacteriochlorophyllide a <=> Bacteriochlorophyllide b R09059 3-hydroxyethylchlorophyllide-a hydro-lyase (chlorophyllide-a-forming); Chlorophyllide + H2O <=> 3-Hydroxyethylchlorophyllide a R09060 3-hydroxyethylbacteriochlorophyllide-a:ferredoxin oxidoreductase; 3-Hydroxyethylchlorophyllide a + 2 Reduced ferredoxin + ATP + H2O + 2 H+ <=> 3-Hydroxyethylbacteriochlorophyllide a + 2 Oxidized ferredoxin + ADP + Orthophosphate R09061 chlorophyllide-a hydrolase; Chlorophyllide + H2O <=> 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2 R09063 S-adenosyl-L-methionine:bacteriochlorophyllide-d C20-methyltransferase; Bacteriochlorophyllide d + S-Adenosyl-L-methionine <=> Bacteriochlorophyllide c + S-Adenosyl-L-homocysteine R09064 trans,trans-farnesyl-diphosphate:bacteriochlorophyllide-c farnesyltransferase; Bacteriochlorophyllide c + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll c + Diphosphate R09065 trans,trans-farnesyl-diphosphate:bacteriochlorophyllide-d farnesyltransferase; Bacteriochlorophyllide d + trans,trans-Farnesyl diphosphate <=> Bacteriochlorophyll d + Diphosphate R09066 7(1)-Hydroxychlorophyllide a <=> Chlorophyllide R09067 chlorophyllide-b:phytyl-diphosphate phytyltransferase; Chlorophyllide b + Phytyl diphosphate <=> Chlorophyll b + Diphosphate R09068 chlorophyll chlorophyllidohydrolase; Chlorophyll b + H2O <=> Chlorophyllide b + Phytol R09069 7(1)-hydroxychlorophyll-a:NAD+ oxidoreductase; 7(1)-Hydroxychlorophyll a + NAD+ <=> Chlorophyll b + NADH + H+ R09070 7(1)-hydroxychlorophyll-a:NADP+ oxidoreductase; 7(1)-Hydroxychlorophyll a + NADP+ <=> Chlorophyll b + NADPH + H+ R09071 7(1)-hydroxychlorophyll a:ferredoxin oxidoreductase; 7(1)-Hydroxychlorophyll a + 2 Reduced ferredoxin + 2 H+ <=> Chlorophyll a + 2 Oxidized ferredoxin + H2O R09072 S-adenosyl-L-methionine:1,2-diacyl-sn-glycerol 3-amino-3-carboxypropyltransferase; 1,2-Diacyl-sn-glycerol + S-Adenosyl-L-methionine <=> Diacylglycerylhomoserine + 5'-Methylthioadenosine R09073 S-adenosylmethionine:diacylglycerylhomoserine N-methyltransferase (diacylglyceryl-N,N,N-trimethylhomoserine-forming); Diacylglycerylhomoserine + 3 S-Adenosyl-L-methionine <=> Diacylglyceryl-N,N,N-trimethylhomoserine + 3 S-Adenosyl-L-homocysteine R09074 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming); N1-Acetylspermidine + Oxygen + H2O <=> Putrescine + 3-Acetamidopropanal + Hydrogen peroxide R09075 N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming); N8-Acetylspermidine + Oxygen + H2O <=> 1,3-Diaminopropane + N4-Acetylaminobutanal + Hydrogen peroxide R09076 spermidine:oxygen oxidoreductase (spermidine-forming); Spermine + Oxygen + H2O <=> Spermidine + 3-Aminopropanal + Hydrogen peroxide R09077 spermidine:oxygen oxidoreductase (3-aminopropanal-forming); Spermidine + Oxygen + H2O <=> Putrescine + 3-Aminopropanal + Hydrogen peroxide R09078 (S)-acetoin:NAD+ oxidoreductase; Diacetyl + NADH + H+ <=> (S)-Acetoin + NAD+ R09079 carboxyspermidine:NADP+ oxidoreductase; Putrescine + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxyspermidine + H2O + NADP+ R09080 carboxynorspermidine:NADP+ oxidoreductase; 1,3-Diaminopropane + L-Aspartate 4-semialdehyde + NADPH + H+ <=> Carboxynorspermidine + H2O + NADP+ R09081 carboxyspermidine carboxy-lyase (spermidine-forming); Carboxyspermidine <=> Spermidine + CO2 R09082 carboxynorspermidine carboxy-lyase (norspermidine-forming); Carboxynorspermidine <=> Norspermidine + CO2 R09083 Reduced FMN + Oxygen <=> Dimethylbenzimidazole + D-Erythrose 4-phosphate + H2O R09084 ADP:D-fructose-6-phosphate 1-phosphotransferase; beta-D-Fructose 6-phosphate + ADP <=> beta-D-Fructose 1,6-bisphosphate + AMP R09085 ADP:D-glucose 6-phosphotransferase; alpha-D-Glucose + ADP <=> alpha-D-Glucose 6-phosphate + AMP R09086 ADP:D-glucose 6-phosphotransferase; beta-D-Glucose + ADP <=> beta-D-Glucose 6-phosphate + AMP R09087 ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase; ATP + Phytic acid <=> ADP + 5-PP-InsP5 R09088 Benzoate + Pyruvate <=> Pyruvophenone + CO2 R09089 Pyruvophenone <=> Cathinone R09090 2-Methylpropanoyl-CoA + 3 Malonyl-CoA <=> 8-Methyl-6-nonenoic acid R09093 Tetrahydrofolate + Formaldehyde <=> 5,10-Methylenetetrahydrofolate + H2O R09094 Formate <=> CO2 R09095 hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase; Methanophenazine + Hydrogen <=> Dihydromethanophenazine R09096 Acetyl-CoA + 5,6,7,8-Tetrahydromethanopterin <=> CoA + 5-Methyl-5,6,7,8-tetrahydromethanopterin + CO R09097 propanal:NAD+ oxidoreductase (CoA-propanoylating); Propanal + NAD+ + CoA <=> Propanoyl-CoA + NADH + H+ R09098 methanol:coenzyme M methyltransferase; Methanol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + H2O R09099 5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase; L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O R09100 D-Fructose 1,6-bisphosphate <=> 3-Phospho-D-glycerate R09102 Bis(4-hydroxyphenyl)methane <=> Bis(4-hydroxyphenyl)methanol R09103 Bis(4-hydroxyphenyl)methanol <=> 4,4'-Dihydroxybenzophenone R09104 4,4'-Dihydroxybenzophenone <=> 4-Hydroxyphenyl-4-hydroxybenzoate R09105 4-Hydroxyphenyl-4-hydroxybenzoate + H2O <=> 4-Hydroxybenzoate + Hydroquinone R09106 feruloyl-CoA:16-hydroxypalmitate feruloyltransferase; Feruloyl-CoA + 16-Hydroxypalmitate <=> CoA + 16-Feruloyloxypalmitate R09107 N-acetyl-L-citrulline amidohydrolase; N-Acetyl-L-citrulline + H2O <=> Acetate + L-Citrulline R09108 Palustradiene <=> Palustradienol R09109 Palustradienol <=> Palustradienal R09110 Palustradienal <=> Palustric acid R09111 (+)-copalyl diphosphate-lyase (isopimara-7,15-diene-forming); Copalyl diphosphate <=> Isopimara-7,15-diene + Diphosphate R09112 Isopimara-7,15-diene <=> Isopimaradienol R09113 Isopimaradienol <=> Isopimaradienal R09114 Isopimaradienal <=> Isopimaric acid R09115 9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming); 9alpha-Copalyl diphosphate <=> Stemar-13-ene + Diphosphate R09116 9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming]; 9alpha-Copalyl diphosphate <=> Stemod-13(17)-ene + Diphosphate R09117 9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming); 9alpha-Copalyl diphosphate <=> 9beta-Pimara-7,15-diene + Diphosphate R09118 9beta-Pimara-7,15-dien-19-oate <=> 3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide R09119 ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming); ent-Copalyl diphosphate <=> ent-Cassa-12,15-diene + Diphosphate R09120 ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming]; ent-Copalyl diphosphate <=> (+)-Sandaracopimaradiene + Diphosphate R09121 ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming]; ent-Copalyl diphosphate <=> ent-Pimara-8(14),15-diene + Diphosphate R09122 geranylgeraniol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating); Geranylgeraniol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Plaunotol + [Oxidized NADPH---hemoprotein reductase] + H2O R09123 geranylgeranyl diphosphate-lyase (fusicocca-2,10(14)-diene-forming); Geranylgeranyl diphosphate <=> Fusicocca-2,10(14)-diene + Diphosphate R09124 trimethylamine:coenzyme M methyltransferase; Trimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Dimethylamine R09125 2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase; 2,5-Dihydroxypyridine + Oxygen <=> N-Formylmaleamic acid R09126 N-formylmaleamic acid amidohydrolase; N-Formylmaleamic acid + H2O <=> Maleamate + Formate R09127 ethanol:cytochrome c oxidoreductase; Ethanol + 2 Ferricytochrome cL <=> Acetaldehyde + 2 Ferrocytochrome cL + 2 H+ R09128 2-chloroethanol:cytochrome c oxidoreductase; 2-Chloroethanol + 2 Ferricytochrome cL <=> Chloroacetaldehyde + 2 Ferrocytochrome cL + 2 H+ R09129 S-(hydroxymethyl)mycothiol:NAD+ oxidoreductase; S-(Hydroxymethyl)mycothiol + NAD+ <=> S-Formylmycothiol + NADH + H+ R09130 1,2,3,4-Tetrachlorobenzene + Oxygen + NADH + H+ <=> cis-Chlorobenzene dihydrodiol + NAD+ R09131 1,2,3,4-Tetrachlorobenzene + Oxygen + NADPH + H+ <=> cis-Chlorobenzene dihydrodiol + NADP+ R09132 cis-Chlorobenzene dihydrodiol + NAD+ <=> Tetrachlorocatechol + NADH + H+ R09133 cis-Chlorobenzene dihydrodiol + NADP+ <=> Tetrachlorocatechol + NADPH + H+ R09134 tetrachlorocatechol:oxygen 1,2-oxidoreductase; Tetrachlorocatechol + Oxygen <=> Tetrachloro-cis,cis-muconate R09135 2,3,5-trichlorodienelactone lyase (decyclizing); Tetrachloro-cis,cis-muconate <=> 2,3,5-Trichlorodienelactone + Hydrochloric acid R09136 2,3,5-trichlorodienelactone lactonohydrolase; 2,3,5-Trichlorodienelactone + H2O <=> 2,3,5-Trichloromaleylacetate R09137 2,4-dichloro-3-oxoadipate:NAD+ oxidoreductase; 2,3,5-Trichloromaleylacetate + 2 NADH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NAD+ + Hydrochloric acid R09138 2,4-dichloro-3-oxoadipate:NADP+ oxidoreductase; 2,3,5-Trichloromaleylacetate + 2 NADPH + 2 H+ <=> 2,4-Dichloro-3-oxoadipate + 2 NADP+ + Hydrochloric acid R09139 2,4-Dichloro-3-oxoadipate <=> CO2 R09140 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 8-epi-Cedrol + Diphosphate R09141 Trichloroethene + NADH + H+ + Oxygen <=> TCE epoxide + NAD+ + H2O R09142 TCE epoxide <=> CO R09143 TCE epoxide <=> Dichloroacetate R09144 TCE epoxide <=> Glyoxylate R09145 TCE epoxide <=> Formate R09146 Trichloroethene <=> Chloral R09147 Trichloroethene <=> TCE epoxide R09148 1,1,1-Trichloroethane + NADH + H+ + Oxygen <=> Trichloroethanol + NAD+ + H2O R09149 Trichloroethanol <=> Chloral R09150 Chloral <=> Trichloroacetate R09151 trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming); Trichloroethene + Oxygen + H2O + NADH + H+ <=> Glyoxylate + 3 Hydrochloric acid + NAD+ R09152 trichloroethene,NADH:oxygen oxidoreductase (formate-forming); Trichloroethene + Oxygen + 2 H2O + NADH + H+ <=> 2 Formate + 3 Hydrochloric acid + NAD+ R09153 Sulfoacetaldehyde <=> Coenzyme M R09154 1,1,1-Trichloroethane <=> 1,1-Dichloroethane + Hydrochloric acid R09155 1,1-Dichloroethane <=> Chloroethane + Hydrochloric acid R09156 chloroethane,donor:oxygen oxidoreductase (dechlorinating, acetaldehyde-forming); Chloroethane + Oxygen + Reduced acceptor <=> Acetaldehyde + Hydrochloric acid + Acceptor + H2O R09157 Trichloroacetate + 2 H2O <=> Oxalate + 3 Hydrochloric acid R09158 Trichloroacetate <=> CO2 R09159 Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+ R09160 Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-7,8-dihydrodiol + NAD+ R09161 Pyrene + Oxygen <=> cis-4,5-Dihydroxy-4,5-dihydropyrene R09162 cis-4,5-dihydroxy-4,5-dihydropyrene:NAD+ 4,5-oxidoreductase; cis-4,5-Dihydroxy-4,5-dihydropyrene + NAD+ <=> 4,5-Dihydroxypyrene + NADH + H+ R09163 4,5-Dihydroxypyrene + Oxygen <=> Phenanthrene-4,5-dicarboxylate R09164 Phenanthrene-4,5-dicarboxylate <=> Phenanthrene-4-carboxylate + CO2 R09165 Phenanthrene-4-carboxylate + Oxygen + NADH + H+ <=> cis-3,4-Phenanthrenedihydrodiol-4-carboxylate + NAD+ R09166 cis-3,4-Phenanthrenedihydrodiol-4-carboxylate <=> Phenanthrene-3,4-diol + CO2 R09167 Pyrene + Oxygen <=> Pyrene-4,5-oxide + H2O R09168 Pyrene-4,5-oxide + H2O <=> trans-4,5-Dihydroxy-4,5-dihydropyrene R09169 Pyrene + Oxygen <=> Pyrene-1,2-oxide + H2O R09170 Pyrene-1,2-oxide <=> 1-Hydroxypyrene R09171 1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-6,7-oxide + H2O R09172 1-Hydroxypyrene-6,7-oxide <=> 1,6-Dihydroxypyrene R09173 1,6-Dihydroxypyrene <=> Pyrene-1,6-dione R09174 1-Hydroxypyrene + Oxygen <=> 1-Hydroxypyrene-7,8-oxide + H2O R09175 1-Hydroxypyrene-7,8-oxide <=> 1,8-Dihydroxypyrene R09176 1,8-Dihydroxypyrene <=> Pyrene-1,8-dione R09177 1-Hydroxypyrene + S-Adenosyl-L-methionine <=> 1-Methoxypyrene + S-Adenosyl-L-homocysteine R09178 1-Methoxypyrene + Oxygen <=> 1-Methoxypyrene-6,7-oxide + H2O R09179 1-Methoxypyrene-6,7-oxide <=> 1-Hydroxy-6-methoxypyrene R09180 1-Hydroxy-6-methoxypyrene + CH3-R <=> 1,6-Dimethoxypyrene + R R09181 1-Hydroxypyrene <=> 1-Pyrenylsulfate R09182 Benzo[a]pyrene-cis-7,8-dihydrodiol + Oxygen <=> cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate R09183 Benzo[a]pyrene-cis-9,10-dihydrodiol + NAD+ <=> 9,10-Dihydroxybenzo[a]pyrene + NADH + H+ R09184 9,10-dihydroxybenzo[a]pyrene:oxygen 10,10a-oxidoreductase (decyclizing); 9,10-Dihydroxybenzo[a]pyrene + Oxygen <=> cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate R09185 cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 10-Oxabenzo[def]chrysen-9-one + Formate R09186 2-dehydro-3-deoxy-D-arabinonate hydro-lyase (2,5-dioxopentanoate-forming); 2-Dehydro-3-deoxy-D-xylonate <=> 2,5-Dioxopentanoate + H2O R09187 C-9 Reduced nonaketamide <=> Nonaketamide monocyclic intermediate + 2 H2O R09188 Nonaketamide monocyclic intermediate <=> Nonaketamide tricyclic intermediate R09189 S-adenosyl-L-methionine:pretetramid C-methyltransferase; S-Adenosyl-L-methionine + Pretetramid <=> S-Adenosyl-L-homocysteine + 6-Methylpretetramide R09190 6-methylpretetramide,NADPH:oxygen oxidoreductase (4,12a-hydroxylating); 6-Methylpretetramide + 2 NADPH + 2 H+ + 2 Oxygen <=> 4-Keto-anhydrotetracycline + 2 NADP+ + 2 H2O R09191 S-adenosyl-L-methionine:4-amino-anhydrotetracycline N-methyltransferase; 4-Amino-anhydrotetracycline + 2 S-Adenosyl-L-methionine <=> Anhydrotetracycline + 2 S-Adenosyl-L-homocysteine R09192 oxytetracycline:coenzyme-F420 oxidoreductase; Oxytetracycline + Coenzyme F420 <=> 5a,11a-Dehydrooxytetracycline + Reduced coenzyme F420 R09195 malonyl-CoA:L-glutamine amido-ligase (AMP-forming); ATP + Malonyl-CoA + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-CoA + L-Glutamate R09196 Nonaketamide tricyclic intermediate <=> Pretetramid R09197 4-Keto-anhydrotetracycline <=> 4-Amino-anhydrotetracycline R09198 5a,11a-dehydrotetracycline,NADPH:oxygen oxidoreductase (5-hydroxylating); 5a,11a-Dehydrotetracycline + NADPH + H+ + Oxygen <=> 5a,11a-Dehydrooxytetracycline + NADP+ + H2O R09201 2,4-Dichlorotoluene + NADH + Oxygen + H+ <=> 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ R09202 cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-8-carboxylate R09203 cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 7,8-Dihydropyrene-7-carboxylate R09204 Benzo[a]pyrene + Oxygen + NADH + H+ <=> Benzo[a]pyrene-cis-4,5-dihydrodiol + NAD+ R09205 Benzo[a]pyrene-cis-4,5-dihydrodiol <=> 4,5-Dihydroxybenzo[a]pyrene R09206 4,5-Dihydroxybenzo[a]pyrene + Oxygen <=> 4,5-Chrysenedicarboxylate R09207 4,5-Chrysenedicarboxylate <=> 4-Chrysenecarboxylate + CO2 R09208 4,5-Chrysenedicarboxylate <=> 5-Chrysenecarboxylate + CO2 R09209 Benzo[a]pyrene + NADH + H+ + Oxygen <=> Benzo[a]pyrene-cis-11,12-dihydrodiol + NAD+ R09210 Benzo[a]pyrene + Oxygen <=> Benzo[a]pyrene-11,12-epoxide R09211 Benzo[a]pyrene-11,12-epoxide + H2O <=> Benzo[a]pyrene-trans-11,12-dihydrodiol R09212 Benzo[a]pyrene-trans-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene R09213 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+ <=> 4,6-Dichloro-3-methylcatechol + NADH + H+ R09214 4,6-Dichloro-3-methylcatechol + Oxygen <=> 3,5-Dichloro-2-methylmuconate R09215 chloromuconate chloromuconate; 3,5-Dichloro-2-methylmuconate <=> 3,5-Dichloro-2-methylmuconolactone R09216 Benzo[a]pyrene-cis-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene R09217 chloromuconate cycloisomerase; 3,5-Dichloro-2-methylmuconolactone <=> 3-Chloro-2-methyldienelactone + Hydrochloric acid R09218 Pyrene-4,5-dione <=> Phenanthrene-4,5-dicarboxylate R09219 Pyrene-4,5-dione + NADH + H+ <=> 4,5-Dihydroxypyrene + NAD+ R09220 dienelactone hydrolase; 3-Chloro-2-methyldienelactone + H2O <=> 3-Chloro-2-methylmaleylacetate R09221 chloromuconate cycloisomerase; 3,5-Dichloro-2-methylmuconate <=> 2-Chloro-5-methyl-cis-dienelactone + Hydrochloric acid R09222 dienelactone hydrolase; 2-Chloro-5-methyl-cis-dienelactone + H2O <=> 2-Chloro-5-methylmaleylacetate R09223 maleylacetate reductase; 2-Chloro-5-methylmaleylacetate + NADH + H+ <=> 5-Methylmaleylacetate + NAD+ + Hydrochloric acid R09224 maleylacetate reductase; 5-Methylmaleylacetate + NADH + H+ <=> 2-Methyl-3-oxoadipate + NAD+ R09225 3-methyl-5-oxo-2,5-dihydrofuran-2-acetate delta3-delat2-isomerase; 3-Methylmuconolactone <=> 4-Methyl-3-oxoadipate-enol-lactone R09226 4-Methyl-3-oxoadipate-enol-lactone + H2O <=> 4-Methyl-3-oxoadipate R09227 Phthalate + Oxygen + NADH + H+ <=> Phthalate 3,4-cis-dihydrodiol + NAD+ R09228 Phthalate 3,4-cis-dihydrodiol + NAD+ <=> 3,4-Dihydroxyphthalate + NADH + H+ R09229 muconate cycloisomerase; 3-Methyl-cis,cis-hexadienedioate <=> 3-Methylmuconolactone R09230 2-Amino-4-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O R09231 2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NAD+ + 2 H2O R09232 2,4-Dinitrotoluene + 3 NADH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NAD+ + 2 H2O R09233 2,4-dinitrotoluene,NADH:oxygen oxidoreductase (4,5-hydroxylating, nitrite-releasing); 2,4-Dinitrotoluene + NADH + Oxygen + H+ <=> 4-Methyl-5-nitrocatechol + NAD+ + Nitrite R09234 4-methyl-5-nitrocatechol,NADPH:oxygen 5-oxidoreductase (5-hydroxylating, nitrite-forming); 4-Methyl-5-nitrocatechol + NADPH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NADP+ + Nitrite + H2O R09235 4-Amino-2-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O R09236 2-Hydroxy-5-methylquinone + NADH + H+ <=> 2,4,5-Trihydroxytoluene + NAD+ R09237 2,4,5-Trihydroxytoluene + Oxygen <=> cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate R09238 cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> (S)-Methylmalonate semialdehyde + Pyruvate R09239 4,5-Dihydroxypyrene <=> Pyrene-4,5-dione R09240 2-Amino-4-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O R09241 2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NADP+ + 2 H2O R09242 2,4-Dinitrotoluene + 3 NADPH + 3 H+ <=> 4-Amino-2-nitrotoluene + 3 NADP+ + 2 H2O R09243 4-Amino-2-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O R09244 (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesylcistransferase (adding 7 isopentenyl units); 2-cis,6-trans-Farnesyl diphosphate + 7 Isopentenyl diphosphate <=> trans,octacis-Decaprenyl diphosphate + 7 Diphosphate R09245 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units); trans,trans-Farnesyl diphosphate + 3 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 3 Diphosphate R09246 geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units); Geranylgeranyl diphosphate + 2 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 2 Diphosphate R09247 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 4 isopentenyl units); trans,trans-Farnesyl diphosphate + 4 Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + 4 Diphosphate R09248 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units); trans,trans-Farnesyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Octaprenyl diphosphate + 5 Diphosphate R09249 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units); trans,trans-Farnesyl diphosphate + 7 Isopentenyl diphosphate <=> all-trans-Decaprenyl diphosphate + 7 Diphosphate R09250 geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units); Geranyl diphosphate + 7 Isopentenyl diphosphate <=> all-trans-Nonaprenyl diphosphate + 7 Diphosphate R09251 geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 5 isopentenyl units); Geranylgeranyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Nonaprenyl diphosphate + 5 Diphosphate R09252 cyclohex-1-ene-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase; Cyclohex-1-ene-1-carbonyl-CoA + Electron-transferring flavoprotein <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Reduced electron-transferring flavoprotein R09253 2-oxo-4-hydroxy-5-aminovalerate hydro-lyase (deaminating; 2,5-dioxopentanoate-forming); 2-Oxo-4-hydroxy-5-aminovalerate <=> 2,5-Dioxopentanoate + Ammonia R09254 L-tyrosine:pyruvate aminotransferase; L-Tyrosine + Pyruvate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Alanine R09255 feruloyl-CoA:agmatine feruloyltransferase; Feruloyl-CoA + Agmatine <=> CoA + Feruloylagmatine R09256 4-coumaroyl-CoA:putrescine N4-coumaroyltransferase; p-Coumaroyl-CoA + Putrescine <=> CoA + p-Coumaroylputrescine R09257 feruloyl-CoA:putrescine feruloyltransferase; Feruloyl-CoA + Putrescine <=> CoA + Feruloylputrescine R09258 8 Malonyl-CoA + Acyl-carrier protein <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA R09259 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] <=> 7,9,12-Octaketide intermediate 1 R09260 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 1 R09261 3,5,7,9,11,13,15,17,19-Nonaoxo-henicosanoyl-[acp] <=> 7,9,12-Decaketide intermediate 4 R09262 7,9,12-Octaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Octaketide intermediate 2 + NADP+ R09263 7,9,12-Decaketide intermediate 1 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 2 + NADP+ R09264 7,9,12-Decaketide intermediate 4 + NADPH + H+ <=> 7,9,12-Decaketide intermediate 5 + NADP+ R09265 7,9,12-Octaketide intermediate 2 <=> 7,9,12-Octaketide intermediate 3 + 2 H2O R09266 7,9,12-Decaketide intermediate 2 <=> 7,9,12-Decaketide intermediate 3 + 2 H2O R09267 7,9,12-Decaketide intermediate 5 <=> 7,9,12-Decaketide intermediate 6 + 2 H2O R09268 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide intermediate 1 + H2O R09269 3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 9,14-Decaketide intermediate 1 + 2 H2O R09270 syringate:tetrahydrofolate N-methyltransferase; Syringic acid + Tetrahydrofolate <=> 3-O-Methylgallate + 5-Methyltetrahydrofolate R09271 3-O-methylgallate:tetrahydrofolate O-methyltransferase; 3-O-Methylgallate + Tetrahydrofolate <=> Gallate + 5-Methyltetrahydrofolate R09272 3-O-methylgallate:oxygen 3,4-oxidoreductase (decyclizing); 3-O-Methylgallate + Oxygen <=> 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate R09273 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate acylhydrolase; 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate + H2O <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + Methanol R09274 4-Carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate <=> 2-Pyrone-4,6-dicarboxylate + Methanol R09275 5,5'-dehydrodivanillate,NADPH:oxygen oxidoreductase (demethylating); 5,5'-Dehydrodivanillate + Oxygen + NADPH + H+ <=> 2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + NADP+ + H2O + Formaldehyde R09276 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl:oxygen 1,2-oxidoreductase (decyclizing); 2,2',3-Trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + Oxygen <=> 4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate R09277 4-[2-(5-carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate 5-carboxy-2-hydroxy-3-methoxybenzoylhydrolase; 4-[2-(5-Carboxy-2-hydroxy-3-methoxyphenyl)-2-oxoethylidene]-2-hydroxy-2-pentenedioate + H2O <=> 5-Carboxyvanillic acid + 4-Methylene-2-oxoglutarate R09278 5-carboxyvanillate 5-carboxy-lyase (vanillate-forming); 5-Carboxyvanillic acid <=> Vanillate + CO2 R09279 4-hydroxybutanoate:CoA ligase (AMP-forming); 4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + AMP + Diphosphate R09280 succinate-semialdehyde:NADP+ oxidoreductase (CoA-acylating); Succinyl-CoA + NADPH + H+ <=> Succinate semialdehyde + NADP+ + CoA R09281 4-hydroxybutanoate:NADP+ oxidoreductase; 4-Hydroxybutanoic acid + NADP+ <=> Succinate semialdehyde + H+ + NADPH R09282 3-methylfumaryl-CoA hydratase; (3S)-citramalyl-CoA hydro-lyase (3-methylfumaryl-CoA-forming); 3-Methylfumaryl-CoA + H2O <=> (3S)-Citramalyl-CoA R09283 2-methylfumaryl-CoA 1,4-CoA-mutase; 2-Methylfumaryl-CoA <=> 3-Methylfumaryl-CoA R09284 3-(hydroxyamino)phenol hydroxymutase; 3-Hydroxyaminophenol <=> 4-Aminocatechol R09285 4-Aminocatechol + H2O <=> Benzene-1,2,4-triol + Ammonia R09286 3-hydroxypropionate:CoA ligase (AMP-forming); 3-Hydroxypropionyl-CoA + Diphosphate + AMP <=> 3-Hydroxypropanoate + CoA + ATP R09287 Aminohydroquinone + H2O <=> Benzene-1,2,4-triol + Ammonia R09288 3-hydroxyaminophenol:NAD+ oxidoreductase; 3-Nitrophenol + 2 NADH + 2 H+ <=> 3-Hydroxyaminophenol + 2 NAD+ + H2O R09289 3-hydroxypropionate:NADP+ oxidoreductase; 3-Hydroxypropanoate + NADP+ <=> 3-Oxopropanoate + NADPH + H+ R09290 UDP-alpha-D-xylose:[protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine 3-alpha-D-xylosyltransferase (configuration-retaining); UDP-D-xylose + G13051 <=> UDP + G03532 R09291 ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating); (2S)-Ethylmalonyl-CoA + NADP+ <=> Crotonoyl-CoA + CO2 + NADPH + H+ R09292 (2R)-ethylmalonyl-CoA CoA-carbonylmutase; (2R)-Ethylmalonyl-CoA <=> (2S)-Methylsuccinyl-CoA R09293 (2S)-methylsuccinyl-CoA:electron-transfer flavoprotein oxidoreductase; (2S)-Methylsuccinyl-CoA + Electron-transferring flavoprotein <=> 2-Methylfumaryl-CoA + Reduced electron-transferring flavoprotein R09295 GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase; GDP-L-fucose + [Protein]-L-serine <=> GDP + G13052 R09296 UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-D-glucosamine + G13052 <=> UDP + G13053 R09297 CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein alpha-(2->3)-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + G13054 <=> CMP + G05914 R09298 CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine alpha-(2->6)-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate + G13054 <=> CMP + G10982 R09299 UDP-D-galactose + G13053 <=> UDP + G13054 R09300 GDP-D-mannose + G13027 <=> GDP + G10737 R09301 GDP-D-mannose + G10737 <=> GDP + G10842 R09302 GDP-D-mannose + G10842 <=> GDP + G10843 R09303 GDP-D-mannose + G10843 <=> GDP + G11055 R09304 UDP-N-acetyl-D-glucosamine + [Protein]-L-serine <=> UDP + G12573 R09305 7,9,12-Octaketide intermediate 3 <=> Octaketide bicyclic intermediate + H2O R09306 Octaketide bicyclic intermediate + NADPH + H+ <=> (S)-Chiral alcohol + NADP+ R09307 (S)-Chiral alcohol <=> (S)-Hemiketal R09308 (S)-Hemiketal <=> (S)-DNPA + H2O R09309 Octaketide bicyclic intermediate + NADPH + H+ <=> (R)-Chiral alcohol + NADP+ R09310 (R)-Chiral alcohol <=> (R)-Hemiketal R09311 (R)-Hemiketal <=> (R)-DNPA + H2O R09312 Dihydrokalafungin + NADH + H+ <=> Dihydrokalafungin dihydroquinone form + NAD+ R09313 dihydrokalafungin-dihydroquinone,FMNH2:oxygen oxidoreductase (hydroxylating); Dihydrokalafungin dihydroquinone form + Reduced FMN + Oxygen <=> DHKred-OH + FMN + H2O R09314 6-Deoxydihydrokalafungin + Reduced FMN + Oxygen <=> Dihydrokalafungin + FMN + H2O R09315 UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051 R09316 UDP-D-glucose + G13052 <=> UDP + G10981 R09317 Methyl-Co(III) corrinoid protein + CoA + CO2 + Reduced ferredoxin <=> Acetyl-CoA + Co(I) corrinoid protein + H2O + Oxidized ferredoxin R09318 GDP-L-fucose + G00179 <=> GDP + G13056 R09319 GDP-L-fucose + G00014 <=> GDP + G10770 R09320 UDP-D-galactose + G10770 <=> UDP + G13057 R09322 quinate:quinone 3-oxidoreductase; Quinate + Quinone <=> 3-Dehydroquinate + Hydroquinone R09323 G13057 + H2O <=> N-Acetyl-D-glucosamine + G13058 R09324 GDP-L-fucose + G13058 <=> GDP + G13059 R09325 7,9,12-Decaketide intermediate 3 <=> Deoxynogalonate R09326 7,9,12-Decaketide intermediate 6 <=> 12-Deoxyaklanonic acid R09327 deoxynogalonate:oxygen oxidoreductase; Deoxynogalonate + Oxygen <=> Nogalonate + H2O R09328 nogalaviketone lyase (ring-opening); methyl nogalonate cyclase; Methyl nogalonate <=> Nogalaviketone R09329 nogalavinone:NADP+ 7-oxidoreductase; Nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+ R09330 Nogalavinone <=> 1-OH-Nogalamycinone R09331 dTDP-beta-L-rhodosamine:aklavinone 7-alpha-L-rhodosaminyltransferase; Aklavinone + dTDP-beta-L-rhodosamine <=> Aclacinomycin T + dTDP R09332 dTDP-2-deoxy-beta-L-fucose:aclacinomycin-T 2-deoxy-alpha-L-fucosyltransferase; Aclacinomycin T + dTDP-2-deoxy-beta-L-fucose <=> Aclacinomycin S + dTDP R09333 Aclacinomycin S <=> Aclacinomycin N R09334 aclacinomycin N:oxygen oxidoreductase; Aclacinomycin N + Oxygen <=> Aclacinomycin A + Hydrogen peroxide R09335 aclacinomycin A:oxygen oxidoreductase; Aclacinomycin A + Oxygen <=> Aclacinomycin Y + Hydrogen peroxide R09336 epsilon-Rhodomycinone <=> epsilon-Rhodomycin T R09337 epsilon-rhodomycin-T acylhydrolase; epsilon-Rhodomycin T + H2O <=> 15-Demethoxy-epsilon-rhodomycin + Methanol R09338 15-Demethoxy-epsilon-rhodomycin + Oxygen + 2 Glutathione <=> beta-Rhodomycin + CO2 + H2O + Glutathione disulfide R09339 methylmercury mercuric-lyase (methane-forming); Methylmercury + H+ <=> Methane + Mercury(2+) R09340 7,9,12-Decaketide intermediate 3 <=> UWM6 R09341 UWM6 <=> Rabelomycin R09342 UWM6 <=> 2,3-Dehydro-UWM6 + H2O R09343 2,3-Dehydro-UWM6 <=> Dehydrorabelomycin R09344 2,3-Dehydro-UWM6 + L-Isoleucine <=> Jadomycin A + CO2 + H2O R09345 dTDP-D-olivose:UWM6 9-C-beta-D-olivosyltransferase; UWM6 + dTDP-D-olivose <=> C1'-C9-Glycosylated UWM6 + dTDP R09346 Rabelomycin <=> 11-Deoxylandomycinone R09347 11-Deoxylandomycinone <=> Landomycin H R09348 8-D-Olivosyl-landomycin <=> Landomycin D R09349 Landomycin D <=> Landomycin E R09350 7,12-Decaketide intermediate 1 <=> Decaketide tricyclic intermediate R09351 dTDP-D-olivose:premithramycin-A3 D-olivosyltransferase; Premithramycin A3 + dTDP-D-olivose <=> 3A-Deolivosylpremithramycin B + dTDP R09352 dTDP-D-olivose:3A-deolivosylpremithramycin-B D-olivosyltransferase; 3A-Deolivosylpremithramycin B + dTDP-D-olivose <=> Premithramycin B + dTDP R09353 premithramycin-B,NADPH:oxygen oxidoreductase; Premithramycin B + NADPH + H+ + Oxygen <=> Mithramycin DK + NADP+ + CO2 R09354 Mithramycin DK <=> Mithramycin R09355 9,14-Decaketide intermediate 1 <=> Tetracenomycin F2 + Acyl-carrier protein R09357 Landomycin H <=> 8-D-Olivosyl-landomycin R09358 (2R)-2-hydroxy-2-methylbutanenitrile butan-2-one-lyase (cyanide forming); (2R)-2-Hydroxy-2-methylbutanenitrile <=> Methyl ethyl ketone + Hydrogen cyanide R09359 (S)-cyanohydrin lyase (cyanide forming); (S)-Hydroxynitrile <=> Cyanide ion + Aldehyde R09360 Landomycin E <=> Landomycin J R09361 Landomycin J <=> Landomycin B R09362 Landomycin B <=> Landomycin A R09363 L-arginine,2-oxoglutarate:oxygen oxidoreductase ((3S)-hydroxylating); L-Arginine + 2-Oxoglutarate + Oxygen <=> beta-Hydroxyarginine + Succinate + CO2 R09364 (2S,3S)-3-hydroxyarginine hydrolyase (cyclizing, (2S,3R)-capreomycidine-forming); beta-Hydroxyarginine <=> L-Capreomycidine + H2O R09365 5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase; Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate R09366 Se-methyl-L-selenocysteine methaneselenol-lyase (deaminating; pyruvate-forming); Se-Methyl-L-selenocysteine + H2O <=> Pyruvate + Ammonia + Methaneselenol R09367 Selenite + 4 Glutathione + 2 H+ <=> Selenodiglutathione + Glutathione disulfide + 3 H2O R09368 Selenodiglutathione + Glutathione <=> Glutathioselenol + Glutathione disulfide R09369 S-adenosyl-L-methionine:methaneselenol Se-methyltransferase; S-Adenosyl-L-methionine + Methaneselenol <=> S-Adenosyl-L-homocysteine + Dimethyl selenide R09370 S-adenosyl-L-methionine:dimethyl-selenide Se-methyltransferase; S-Adenosyl-L-methionine + Dimethyl selenide <=> S-Adenosyl-L-homocysteine + Trimethylselenonium R09371 S-adenosyl-L-methionine:hydrogen-selenide Se-methyltransferase; S-Adenosyl-L-methionine + Hydrogen selenide <=> S-Adenosyl-L-homocysteine + Methaneselenol R09372 methaneselenol:NADP+ oxidoreductase; 2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol R09373 L-methionine:methylselenopyruvate aminotransferase; Se-Methyl-L-selenocysteine + 4-Methylthio-2-oxobutanoic acid <=> Methylselenopyruvate + L-Methionine R09374 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one amidohydrolase; 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O <=> 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + Formate R09375 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one:NAD+ 1'-oxidoreductase; 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD+ R09376 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one:NADP+ 1'-oxidoreductase; 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NADPH + H+ <=> 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NADP+ R09377 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one 2-aminohydrolase; 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O <=> 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + Ammonia R09378 ATP:(R)-pantoate 4-phosphotransferase; ATP + (R)-Pantoate <=> ADP + (R)-4-Phosphopantoate R09379 (R)-4-phosphopantoate:beta-alanine ligase (AMP-forming); ATP + (R)-4-Phosphopantoate + beta-Alanine <=> AMP + Diphosphate + D-4'-Phosphopantothenate R09380 acyl-ACP:sn-glycerol-3-phosphate 1-O-acyltransferase; Acyl-[acyl-carrier protein] + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-carrier protein R09381 acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase; Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate R09382 CTP,CTP,ATP:tRNA cytidylyl,cytidylyl,adenylyltransferase; tRNA precursor + 2 CTP + ATP <=> tRNA with a 3' CCA end + 3 Diphosphate R09383 CTP:tRNA cytidylyltransferase; tRNA precursor + CTP <=> tRNA with a 3' cytidine + Diphosphate R09384 CTP:tRNA cytidylyltransferase; tRNA with a 3' cytidine + CTP <=> tRNA with a 3' CC end + Diphosphate R09385 (S)-limonene,NADH:oxygen oxidoreductase; (S)-Limonene + NADH + H+ + Oxygen <=> (4S)-Limonene-1,2-epoxide + NAD+ + H2O R09386 ATP:tRNA adenylyltransferase; tRNA with a 3' CC end + ATP <=> tRNA with a 3' CCA end + Diphosphate R09387 limonene-1,2-epoxide hydrolase; (4S)-Limonene-1,2-epoxide + H2O <=> (1R,2R,4S)-Limonene-1,2-diol R09388 (1R,2R,4S)-menth-8-ene-1,2-diol:NAD+ 2-oxidoreductase; (1R,2R,4S)-Limonene-1,2-diol + NAD+ <=> (1R,4S)-1-Hydroxy-2-oxolimonene + NADH + H+ R09389 (S)-limonene,NADPH:oxygen oxidoreductase; (S)-Limonene + NADPH + Oxygen + H+ <=> (4S)-Limonene-1,2-epoxide + NADP+ + H2O R09390 (1R,4S)-1-hydroxymenth-8-en-2-one,NADPH:oxygen oxidoreductase; (1R,4S)-1-Hydroxy-2-oxolimonene + NADPH + Oxygen + H+ <=> (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O R09391 (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3S)-3-Isopropenyl-6-oxoheptanoate R09392 (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone <=> (3R)-3-Isopropenyl-6-oxoheptanoate R09393 limonene,NADPH:oxygen oxidoreductase; (R)-Limonene + NADPH + Oxygen + H+ <=> Limonene-1,2-epoxide + NADP+ + H2O R09394 GTP 3',8-cyclase [(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate-forming]; GTP + S-Adenosyl-L-methionine + Reduced acceptor <=> (8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-Deoxyadenosine + L-Methionine + Acceptor R09395 thiocarboxylated molybdopterin synthase:cyclic pyranopterin phosphate sulfurtransferase; Precursor Z + 2 Thiocarboxy-[sulfur-carrier protein] <=> Molybdopterin + 2 Sulfur-carrier protein R09397 GTP:2-phospho-L-lactate guanylyltransferase; (2S)-2-Phospholactate + GTP <=> (2S)-Lactyl-2-diphospho-5'-guanosine + Diphosphate R09398 (2S)-lactyl-2-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase; 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + (2S)-Lactyl-2-diphospho-5'-guanosine <=> Coenzyme F420-0 + GMP R09399 L-glutamate:coenzyme F420-0 ligase (GDP-forming); Coenzyme F420-0 + GTP + L-Glutamate <=> Coenzyme F420-1 + GDP + Orthophosphate R09400 L-glutamate:coenzyme F420-1 ligase (GDP-forming); Coenzyme F420-1 + GTP + L-Glutamate <=> Coenzyme F420 + GDP + Orthophosphate R09401 L-glutamate:coenzyme gamma-F420-2 (ADP-forming); ATP + Coenzyme F420 + L-Glutamate <=> ADP + Coenzyme F420-3 + Orthophosphate R09402 codeine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating); Codeine + 2-Oxoglutarate + Oxygen <=> Morphine + Formaldehyde + Succinate + CO2 R09403 L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Isoleucine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-2-Methylbutanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R09404 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin Q1 + H2O + NADP+ R09405 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin M1 + H2O + NADP+ R09406 Aflatoxin M1 + Oxygen + NADPH + H+ <=> Aflatoxin-M1-8,9-epoxide + H2O + NADP+ R09407 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-endo-8,9-epoxide + H2O + NADP+ R09408 Aflatoxin B1 + Oxygen + NADPH + H+ <=> Aflatoxin B1-exo-8,9-epoxide + H2O + NADP+ R09409 glutathione-S-transferase; Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH R09410 epoxide hydrolase; Aflatoxin B1-exo-8,9-epoxide + H2O <=> Aflatoxin B1 diol R09411 Aflatoxin B1 diol <=> Aflatoxin B1 dialdehyde R09412 Aflatoxin B1 dialdehyde <=> 1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal R09413 Aflatoxin B1 dialdehyde <=> alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde R09414 1,2,3,4-Tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione R09415 alpha-(1,2-Dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde <=> 6-[2,3-Dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione R09416 7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O + NADP+ R09417 microsomal epoxide hydrolase; 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O <=> trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene R09418 trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol + H2O + NADP+ R09419 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating); Malonyl-CoA + Acyl-CoA <=> 3-Oxoacyl-CoA + CoA + CO2 R09420 carbonyl reductase; 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + NADPH + H+ <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + NADP+ R09421 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+ R09422 Apoferritin + n Fe3+ <=> Ferritin R09423 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+ R09424 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol + H2O + NADP+ R09425 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + Oxygen + NADPH + H+ <=> alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol + H2O + NADP+ R09426 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP R09427 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP R09428 UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); UDP-glucuronate + Acceptor <=> UDP + Acceptor beta-D-glucuronoside R09429 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone <=> 4-(Methylnitrosamino)-1-(1-oxido-3-pyridinyl)-1-butanone R09430 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol <=> 4-(Methylnitrosamino)-1-(3-pyridyl-N-oxide)-1-butanol R09431 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone <=> 4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + Formaldehyde R09432 alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol <=> alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + Formaldehyde R09433 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone <=> 4-Oxo-1-(3-pyridyl)-1-butanone + N-Nitrosomethanamine R09434 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol <=> 5-(3-Pyridyl)-2-hydroxytetrahydrofuran + N-Nitrosomethanamine R09435 4-(Nitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O <=> 4-Hydroxy-1-(3-pyridinyl)-1-butanone + Nitrogen + H2O R09436 alpha-[3-(Nitrosoamino)propyl]-3-pyridinemethanol + H2O <=> 1-(3-Pyridinyl)-1,4-butanediol + Nitrogen + H2O R09438 4-Hydroxy-1-(3-pyridinyl)-1-butanone <=> 3-Succinoylpyridine R09439 5-(3-Pyridyl)-2-hydroxytetrahydrofuran <=> gamma-Hydroxy-3-pyridinebutanoate R09440 1-(3-Pyridinyl)-1,4-butanediol <=> gamma-Hydroxy-3-pyridinebutanoate R09441 7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene + H2O + NADP+ R09442 7,12-Dimethylbenz[a]anthracene + Oxygen + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O + NADP+ R09443 microsomal epoxide hydrolase; 7,12-Dimethylbenz[a]anthracene 5,6-oxide + H2O <=> trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene R09444 3'-phosphoadenylyl-sulfate:7-hydroxymethyl-12-methylbenz[a]anthracene sulfotransferase; 7-Hydroxymethyl-12-methylbenz[a]anthracene + 3'-Phosphoadenylyl sulfate <=> 7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate + Adenosine 3',5'-bisphosphate R09445 nitrous-oxide:menaquinone oxidoreductase; 2 Nitric oxide + Menaquinol <=> Nitrous oxide + Menaquinone + H2O R09446 nitrous-oxide:NADP+ oxidoreductase; 2 Nitric oxide + NADPH + H+ <=> Nitrous oxide + NADP+ + H2O R09447 D-Glucuronate + NAD+ + H2O <=> D-Glucarate + NADH + H+ R09448 16-Hydroxypalmitate <=> 16-Oxopalmitate R09449 very-long-chain acyl-CoA:NADP+ oxidoreductase; trans-2,3-Dehydroacyl-CoA + NADPH + H+ <=> Long-chain acyl-CoA + NADP+ R09450 long-chain fatty-acyl-CoA hydrolase; Long-chain acyl-CoA + H2O <=> Long-chain fatty acid + CoA R09451 hexadecanoic acid:fatty acid omega-hydroxylase; Hexadecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxypalmitate + [Oxidized NADPH---hemoprotein reductase] + H2O R09452 (9Z)-octadecenoic acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); (9Z)-Octadecenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleate + [Oxidized NADPH---hemoprotein reductase] + H2O R09453 cis-9,10-epoxystearate,NADPH:oxygen oxidoreductase (18-hydroxylating); 9,10-Epoxystearate + NADPH + Oxygen + H+ <=> 9,10-Epoxy-18-hydroxystearate + NADP+ + H2O R09454 docosanoate,NADPH:oxygen oxidoreductase (22-hydroxylating); Docosanoic acid + NADPH + Oxygen + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O R09455 18-Hydroxyoleate <=> 18-Oxooleate R09456 22-Hydroxydocosanoate <=> 22-Oxodocosanoate R09457 16-Oxopalmitate <=> Hexadecanedioate R09458 18-oxooleate:omega-oxo-fatty acid dehydrogenase; 18-Oxooleate <=> Octadec-9-ene-1,18-dioic-acid R09459 22-Oxodocosanoate <=> Docosanedioate R09460 16-hydroxypalmitate,NADPH:oxygen oxidoreductase (10-hydroxylating); 16-Hydroxypalmitate + NADPH + Oxygen + H+ <=> 10,16-Dihydroxyhexadecanoic acid + NADP+ + H2O R09461 9,10-dihydroxystearate,NADPH:oxygen oxidoreductase (18-hydroxylating); 9,10-Dihydroxystearate + NADPH + Oxygen + H+ <=> 9,10,18-Trihydroxystearate + NADP+ + H2O R09462 oleate:lipid-hydroperoxide oxidoreductase (9,10-epoxidising); (9Z)-Octadecenoic acid + Lipid hydroperoxide <=> 9,10-Epoxystearate + Alcohol R09463 18-hydroxyoleate:lipid-hydroperoxide oxidoreductase (9,10-epoxidising); 18-Hydroxyoleate + Lipid hydroperoxide <=> 9,10-Epoxy-18-hydroxystearate + Alcohol R09464 9,10-epoxy-18-hydroxystearate hydrolase; 9,10-Epoxy-18-hydroxystearate + H2O <=> 9,10,18-Trihydroxystearate R09465 9,10-epoxystearate hydrolase; 9,10-Epoxystearate + H2O <=> 9,10-Dihydroxystearate R09466 aldehyde decarbonylase; Long-chain aldehyde <=> Alkane + CO R09467 Alkane <=> Secondary alcohol R09468 Secondary alcohol <=> Ketone R09469 Ketone <=> Diketone R09470 long-chain-primary-alcohol:NADP+ oxidoreductase (CoA-acylating); Long-chain acyl-CoA + 2 NADPH + 2 H+ <=> Primary alcohol + 2 NADP+ + CoA R09471 6-Hydroxypseudooxynicotine + 2 H2O <=> 6-Hydroxy-3-succinoylpyridine + Methylamine R09472 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing); 6-Hydroxy-3-succinoylpyridine + 2 NADH + 2 H+ + Oxygen <=> 2,5-Dihydroxypyridine + Succinate semialdehyde + 2 NAD+ + H2O R09473 nicotinate:cytochrome 6-oxidoreductase (hydroxylating); Nicotinate + H2O + 2 Ferricytochrome <=> 6-Hydroxynicotinate + 2 Ferrocytochrome + 2 H+ R09474 Long-chain acyl-CoA <=> Wax ester R09475 acetate:[acyl-carrier-protein] ligase (AMP-forming); ATP + Acetate + Acyl-carrier protein <=> AMP + Diphosphate + Acetyl-[acyl-carrier protein] R09476 (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming); (S)-2,3-Epoxysqualene <=> Taraxerol R09477 xylitol:NAD+ oxidoreductase; Xylitol + NAD+ <=> D-Xylose + NADH + H+ R09478 2-hydroxyethylphosphonate:NAD+ oxidoreductase; 2-Hydroxyethylphosphonate + NAD+ <=> Phosphonoacetaldehyde + NADH + H+ R09479 ethanol:quinone oxidoreductase; Ethanol + Ubiquinone <=> Acetaldehyde + Ubiquinol R09480 alcohol:azurin oxidoreductase; Primary alcohol + 2 Oxidized azurin <=> Aldehyde + 2 Reduced azurin + 2 H+ R09481 formate:[oxidized hydrogenase] oxidoreductase; Formate + Oxidized hydrogenase <=> CO2 + Reduced hydrogenase R09482 malonyl-[acyl-carrier-protein] carboxy-lyase; Malonyl-[acyl-carrier protein] <=> Acetyl-[acyl-carrier protein] + CO2 R09483 malonate carboxy-lyase (biotin-independent/biotin-dependent); Malonate <=> Acetate + CO2 R09484 long-chain-aldehyde:NAD+ oxidoreductase (acyl-[acyl-carrier protein]-forming); Long-chain aldehyde + Acyl-carrier protein + NAD+ <=> Long-chain acyl-[acyl-carrier protein] + NADH + H+ R09485 long-chain-aldehyde:NADP+ oxidoreductase (acyl-[acyl-carrier protein]-forming); Long-chain aldehyde + Acyl-carrier protein + NADP+ <=> Long-chain acyl-[acyl-carrier protein] + NADPH + H+ R09486 oxalate:ferredoxin oxidoreductase; Oxalate + 2 Oxidized ferredoxin <=> 2 CO2 + 2 Reduced ferredoxin + 2 H+ R09487 germacradienol geosmin-lyase (acetone forming); (1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol + H2O <=> Geosmin + Acetone R09488 indole-3-carboxylate carboxy-lyase; Indole-3-carboxylate <=> Indole + CO2 R09489 protoporphyrinogen IX:quinone oxidoreductase; Protoporphyrinogen IX + 3 Quinone <=> Protoporphyrin + 3 Hydroquinone R09491 (3Z)-phycoerythrobilin:ferredoxin oxidoreductase (from biliverdin IXalpha); (3Z)-Phycoerythrobilin + 2 Oxidized ferredoxin <=> Biliverdin + 2 Reduced ferredoxin R09492 menaquinol:O2 oxidoreductase (H+-transporting); 2 Menaquinol + Oxygen + n H+ <=> 2 Menaquinone + 2 H2O + n H+ R09493 D-amino acid:quinone oxidoreductase (deaminating); D-Amino acid + H2O + Quinone <=> 2-Oxo acid + Ammonia + Hydroquinone R09494 formate:quinone oxidoreductase; Formate + Quinone <=> CO2 + Hydroquinone R09495 L-saccharopine:oxygen oxidoreductase (L-glutamate forming); N6-(L-1,3-Dicarboxypropyl)-L-lysine + H2O + Oxygen <=> L-2-Aminoadipate 6-semialdehyde + L-Glutamate + Hydrogen peroxide R09496 D-proline:acceptor oxidoreductase; D-Proline + Acceptor <=> 1-Pyrroline-2-carboxylate + Reduced acceptor R09497 nitrite:quinone oxidoreductase; Nitrate + Hydroquinone <=> Nitrite + Quinone + H2O R09498 dimethylsulfone reductase; Dimethyl sulfoxide + H2O + NAD+ <=> Dimethyl sulfone + NADH + H+ R09499 hydrogen-sulfide:flavocytochrome c oxidoreductase; Hydrogen sulfide + 2 Ferricytochrome c <=> Sulfur + 2 Ferrocytochrome c + 2 H+ R09500 dimethyl sulfide:ferricytochrome-c2 oxidoreductase; Dimethyl sulfide + 2 Ferricytochrome c2 + H2O <=> Dimethyl sulfoxide + 2 Ferrocytochrome c2 + 2 H+ R09501 dimethyl sulfide:menaquinone oxidoreductase; Dimethyl sulfide + Menaquinone + H2O <=> Dimethyl sulfoxide + Menaquinol R09502 ferredoxin:thioredoxin disulfide oxidoreductase; 2 Reduced ferredoxin + Thioredoxin disulfide + 2 H+ <=> 2 Oxidized ferredoxin + Thioredoxin R09503 H2O:plastoquinone reductase (light-dependent); 2 H2O + 2 Plastoquinone + 4 hn <=> Oxygen + 2 Plastoquinol R09504 ubiquinol:oxygen oxidoreductase (non-electrogenic); 2 Ubiquinol + Oxygen <=> 2 Ubiquinone + 2 H2O R09505 bromide:hydrogen-peroxide oxidoreductase; Alkane + Hydrobromic acid + Hydrogen peroxide <=> RBr + 2 H2O R09506 thioredoxin:(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate oxidoreductase; Thioredoxin + Prostaglandin H2 <=> Thioredoxin disulfide + Prostaglandin F2alpha R09507 substrate:hydrogen peroxide oxidoreductase (RH-hydroxylating or -epoxidising); Alkane + Hydrogen peroxide <=> ROH + H2O R09508 hydrogen:NAD+, ferredoxin oxidoreductase; 2 Hydrogen + NAD+ + 2 Oxidized ferredoxin <=> 5 H+ + NADH + 2 Reduced ferredoxin R09509 carboxybiotinyl-[protein] carboxy-lyase; Carboxybiotinyl-[protein] + H+ <=> Biotinyl-[protein] + CO2 R09510 protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6,N6-dimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6-methyl-L-lysine + Succinate + Formaldehyde + CO2 R09511 protein-N6-methyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6-methyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein lysine + Succinate + Formaldehyde + CO2 R09512 9H-carbazole,NADPH:oxygen oxidoreductase (2,3-hydroxylating); Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+ R09513 methanesulfonate,NADH:oxygen oxidoreductase; Methanesulfonic acid + NADH + H+ + Oxygen <=> Formaldehyde + NAD+ + Sulfite + H2O R09514 urate,NADH:oxygen oxidoreductase (5-hydroxyisourate forming); Urate + NADH + H+ + Oxygen <=> 5-Hydroxyisourate + NAD+ + H2O R09515 calcitriol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating); Calcitriol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitetrol + 2 Oxidized adrenal ferredoxin + H2O R09516 calcidiol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating); Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Secalciferol + 2 Oxidized adrenal ferredoxin + H2O R09517 anthranilate,FAD:oxygen oxidoreductase (3-hydroxylating); Anthranilate + FADH2 + Oxygen <=> 3-Hydroxyanthranilate + FAD + H2O R09518 methane,quinol:oxygen oxidoreductase; Methane + Hydroquinone + Oxygen <=> Methanol + Quinone + H2O R09519 ammonia monooxygenase; Ammonia + Reduced acceptor + Oxygen <=> Hydroxylamine + Acceptor + H2O R09520 FADH2:NADP+ oxidoreductase; FAD + NADPH + H+ <=> FADH2 + NADP+ R09521 L-tyrosine,iodide:NADP+ oxidoreductase (iodinating); L-Tyrosine + NADP+ + Iodide <=> 3-Iodo-L-tyrosine + NADPH R09522 L-tyrosine,iodide:NADP+ oxidoreductase (iodinating); 3-Iodo-L-tyrosine + NADP+ + Iodide <=> 3,5-Diiodo-L-tyrosine + NADPH R09523 S-adenosylmethionine:iodide methyltransferase; S-Adenosyl-L-methionine + Iodide + H+ <=> S-Adenosyl-L-homocysteine + Methyl iodide R09524 acetyl-CoA:acetaldehyde acetyltransferase; Acetoin + CoA + NAD+ <=> Acetaldehyde + Acetyl-CoA + NADH + H+ R09525 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (zingiberene-forming); trans,trans-Farnesyl diphosphate <=> Zingiberene + Diphosphate R09526 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (beta-eudesmol-forming); trans,trans-Farnesyl diphosphate + H2O <=> beta-Eudesmol + Diphosphate R09527 acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating); Acetyl-CoA + Malonyl-CoA <=> Acetoacetyl-CoA + CoA + CO2 R09528 benzoyl-CoA:benzyl alcohol O-benzoyltransferase; Benzoyl-CoA + Benzyl alcohol <=> Benzyl benzoate + CoA R09529 UDP-D-glucuronate:5,6,7-trihydroxyflavone 7-O-glucuronosyltransferase; UDP-glucuronate + Baicalein <=> UDP + Baicalin R09530 sulfite:O-phospho-L-serine sulfotransferase (phosphate-hydrolysing, L-cysteate-forming); O-phospho-L-serine:sulfite 2-amino-2-carboxyethyltransferase; O-Phospho-L-serine + Sulfite <=> L-Cysteate + Orthophosphate R09531 S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing); S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Thermospermine + H+ R09532 2,3-bisphospho-D-glycerate 3-phosphohydrolase; 2,3-Bisphospho-D-glycerate + H2O <=> 2-Phospho-D-glycerate + Orthophosphate R09533 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase; Baicalin + H2O <=> Baicalein + D-Glucuronate R09534 hesperetin 7-(6-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranoside) 6-O-alpha-rhamnopyranosyl-beta-glucohydrolase; Hesperidin + H2O <=> Hesperetin + Rutinose R09535 Angiotensin II + H2O <=> Angiotensin (1-7) + L-Phenylalanine R09536 fatty acylamide amidohydrolase; Anandamide + H2O <=> Arachidonate + Ethanolamine R09537 fatty acylamide amidohydrolase; Oleamide + H2O <=> (9Z)-Octadecenoic acid + Ammonia R09538 CDP-choline phosphohydrolase; CDP-choline + H2O <=> CMP + Choline phosphate R09539 salicylate carboxy-lyase; Salicylate <=> Phenol + CO2 R09540 2 Ascorbate + Hydrogen peroxide <=> 2 Monodehydroascorbate + 2 H2O R09541 Fe(II):NADP+ oxidoreductase; 2 Fe2+ + NADP+ + H+ <=> 2 Fe3+ + NADPH R09542 plastocyanin:ferredoxin oxidoreductase (light-dependent); Reduced plastocyanin + Oxidized ferredoxin + hn <=> Oxidized plastocyanin + Reduced ferredoxin R09543 S-adenosyl-L-methionine:malonyl-[acyl-carrier protein] O-methyltransferase; S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] <=> S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester R09544 D-arabitol-phosphate:NAD+ oxidoreductase; D-Arabinitol 1-phosphate + NAD+ <=> D-Xylulose 5-phosphate + NADH + H+ R09545 (R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase; (R)-2,3-Dihydroxypropane-1-sulfonate + 2 NAD+ + H2O <=> (2R)-3-Sulfolactate + 2 NADH + 2 H+ R09548 germacra-1(10),4,11(13)-trien-12-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Germacra-1(10),4,11(13)-trien-12-ol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Germacrene A acid + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R09549 (+)-germacrene-A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); (+)-Germacrene A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R09550 D-glucose-6-phosphate:F420 1-oxidoreductase; D-Glucose 6-phosphate + Coenzyme F420 <=> D-Glucono-1,5-lactone 6-phosphate + Reduced coenzyme F420 R09551 L-sorbose:acceptor 1-oxidoreductase; L-Sorbose + Acceptor <=> L-Sorbosone + Reduced acceptor R09552 ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase; Ethanol + N,N-Dimethyl-4-nitrosoaniline <=> Acetaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline R09553 methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase; Methanol + N,N-Dimethyl-4-nitrosoaniline <=> Formaldehyde + 4-(Hydroxylamino)-N,N-dimethylaniline R09554 3,4-didehydroadipyl-CoA semialdehyde:NADP+ oxidoreductase; 3,4-Didehydroadipyl-CoA semialdehyde + NADP+ + H2O <=> 3,4-Didehydroadipyl-CoA + NADPH + H+ R09555 benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-epoxydizing); Benzoyl-CoA + NADPH + H+ + Oxygen <=> 2,3-Epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O R09556 2,3-epoxy-2,3-dihydrobenzoyl-CoA (3Z)-6-oxohex-3-enoyl-CoA-lyase (formate-forming); 2,3-Epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O <=> 3,4-Didehydroadipyl-CoA semialdehyde + Formate R09557 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating); Sulfoacetaldehyde + CoA + NADP+ <=> Sulfoacetyl-CoA + NADPH + H+ R09558 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-D-forming]; trans,trans-Farnesyl diphosphate <=> (+)-Germacrene D + Diphosphate R09559 (2S)-2-amino-4-deoxychorismate:FMN oxidoreductase; 2-Amino-2-deoxyisochorismate + FMN <=> 3-(1-Carboxyvinyloxy)anthranilate + Reduced FMN R09560 7-chloro-L-tryptophan:oxygen oxidoreductase; 7-Chloro-L-tryptophan + Oxygen <=> 2-Imino-3-(7-chloroindol-3-yl)propanoate + Hydrogen peroxide R09561 glutathione amide:NAD+ oxidoreductase; 2 Glutathione amide + NAD+ <=> Glutathione amide disulfide + NADH + H+ R09562 S-(2E,6E)-farnesyl-L-cysteine oxidase; Farnesylcysteine + Oxygen + H2O <=> 2-trans,6-trans-Farnesal + L-Cysteine + Hydrogen peroxide R09563 glutathione amide:hydrogen-peroxide oxidoreductase; 2 Glutathione amide + Hydrogen peroxide <=> Glutathione amide disulfide + 2 H2O R09564 chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming); Cl- + Hydrogen peroxide + H+ <=> Hypochlorous acid + H2O R09565 gallate:oxygen oxidoreductase; Gallate + Oxygen <=> (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate R09566 2-imino-3-(7-chloroindol-3-yl)propanoate ammonia-lyase (dichlorochromopyrrolate-forming); 2-imino-3-(7-chloroindol-3-yl)propanoate:oxygen oxidoreductase (dichlorochromopyrrolate-forming); 4 2-Imino-3-(7-chloroindol-3-yl)propanoate + Oxygen <=> 2 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 2 Ammonia + 2 H2O R09567 dichlorochromopyrrolate,NADH:oxygen 2,5-oxidoreductase (dichloroarcyriaflavin A-forming); 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 4 Oxygen + 4 NADH + 4 H+ <=> Dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ R09568 4'-demethylrebeccamycin D-glucose-lyase; 4'-O-Demethylrebeccamycin + H2O <=> Dichloroarcyriaflavin A + beta-D-Glucose R09569 S-adenosyl-L-methionine:demethylrebeccamycin-D-glucose O-methyltransferase; 4'-O-Demethylrebeccamycin + S-Adenosyl-L-methionine <=> Rebeccamycin + S-Adenosyl-L-homocysteine R09570 L-tryptophan:FADH2 oxidoreductase (7-halogenating); L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 7-Chloro-L-tryptophan + FAD + 2 H2O R09571 dinoflagellate-luciferin:oxygen 13-oxidoreductase; Dinoflagellate luciferin + Oxygen <=> Oxidized dinoflagellate luciferin + H2O + hn R09572 L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); L-Proline + 2-Oxoglutarate + Oxygen <=> cis-3-Hydroxy-L-proline + Succinate + CO2 R09573 5-epiaristolochene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (1- and 3-hydroxylating); 5-Epiaristolochene + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Capsidiol + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09574 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-5-epiaristolochene-forming]; trans,trans-Farnesyl diphosphate <=> 5-Epiaristolochene + Diphosphate R09575 germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Costunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09576 (-)-vetispiradiene,[reduced NADPH---hemoprotein reductase]:oxygen 2alpha-oxidoreductase; Vetispiradiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Solavetivol + [Oxidized NADPH---hemoprotein reductase] + H2O R09577 solavetivol,[reduced NADPH---hemoprotein reductase]:oxygen 2alpha-oxidoreductase; Solavetivol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Solavetivone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09578 L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating); L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-Phenylacetaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R09579 L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating); L-Phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O R09580 N-hydroxy-L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating); N-Hydroxy-L-phenylalanine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-phenylalanine + [Oxidized NADPH---hemoprotein reductase] + H2O R09581 N,N-Dihydroxy-L-phenylalanine <=> (E)-Phenylacetaldoxime + CO2 + H2O R09583 L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Tryptophan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N-Hydroxy-L-tryptophan + [Oxidized NADPH---hemoprotein reductase] + H2O R09584 N-hydroxy-L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); N-Hydroxy-L-tryptophan + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N,N-Dihydroxy-L-tryptophan + [Oxidized NADPH---hemoprotein reductase] + H2O R09585 N,N-Dihydroxy-L-tryptophan <=> Indole-3-acetaldehyde oxime + CO2 + H2O R09586 pyrrole-2-carboxylate,NADH:oxygen oxidoreductase (5-hydroxylating); Pyrrole-2-carboxylate + NADH + H+ + Oxygen <=> 5-Hydroxypyrrole-2-carboxylate + NAD+ + H2O R09587 progesterone,reduced-ferredoxin:oxygen oxidoreductase (15beta-hydroxylating); Progesterone + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> 15beta-Hydroxyprogesterone + 2 Oxidized [2Fe-2S] ferredoxin + H2O R09588 D-alanine:(R)-lactate ligase (ADP-forming); D-Alanine + (R)-Lactate + ATP <=> D-Alanyl-(R)-lactate + ADP + Orthophosphate R09589 3-hydroxybenzoate:CoA ligase (AMP-forming); ATP + 3-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 3-Hydroxybenzoyl-CoA R09590 D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming); ATP + D-Aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n <=> [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + Orthophosphate R09591 L-cysteine:1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol ligase (AMP-forming); 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-Cysteine + ATP <=> 1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + Diphosphate R09592 cyanophycin:L-aspartate ligase (ADP-forming); ATP + [L-Asp(4-L-Arg)]n + L-Aspartate <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n-L-Asp R09593 cyanophycin:L-arginine ligase (ADP-forming); ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-Arginine <=> ADP + Orthophosphate + [L-Asp(4-L-Arg)]n+1 R09594 tetrahydromethanopterin:alpha-L-glutamate ligase (ADP-forming); ATP + 5,6,7,8-Tetrahydromethanopterin + L-Glutamate <=> ADP + Orthophosphate + Tetrahydrosarcinapterin R09595 D-alanine:D-serine ligase (ADP-forming); D-Alanine + D-Serine + ATP <=> D-Alanyl-D-serine + ADP + Orthophosphate R09596 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:D-lysine alpha-ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-Lysine <=> ADP + Orthophosphate + N6-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine R09597 L-lysine:[tRNA(Ile2)]-cytidine34 ligase (AMP-forming); [tRNA(Ile2)]-cytidine34 + L-Lysine + ATP <=> [tRNA(Ile2)]-lysidine34 + AMP + Diphosphate + H2O R09598 Cobyrinate + L-Glutamine + ATP + H2O <=> Cobyrinate c-monamide + L-Glutamate + ADP + Orthophosphate R09599 Cobyrinate c-monamide + L-Glutamine + ATP + H2O <=> Cob(II)yrinate a,c diamide + L-Glutamate + ADP + Orthophosphate R09600 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate 2-epimerase; UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate R09601 all-trans-8'-apo-beta-carotenal:oxygen 15,15'-oxidoreductase (bond-cleaving); all-trans-8'-Apo-beta-carotenal + Oxygen <=> Retinal + (2E,4E,6E)-2,6-Dimethylocta-2,4,6-trienedial R09602 pratensein,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming); Pratensein + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-Hydroxypseudobaptigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09603 zeaxanthin:oxygen 7',8'-oxidoreductase (bond-cleaving); Zeaxanthin + 2 Oxygen <=> Crocetin dialdehyde + 2 (3S)-3-Hydroxycyclocitral R09604 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (24-hydroxylating); beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 24-Hydroxy-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O R09605 sophoradiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (24-hydroxylating); Sophoradiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Soyasapogenol B + [Oxidized NADPH---hemoprotein reductase] + H2O R09606 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-alpha-gurjunene-forming]; trans,trans-Farnesyl diphosphate <=> (-)-alpha-Gurjunene + Diphosphate R09607 (2Z,6Z)-farnesyl diphosphate lyase (cyclizing;(-)-endo-alpha-bergamotene-forming); 2-cis,6-cis-Farnesyl diphosphate <=> (-)-endo-alpha-Bergamotene + Diphosphate R09608 (2Z,6Z)-farnesyl diphosphate lyase (cyclizing;(+)-alpha-santalene-forming); 2-cis,6-cis-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate R09609 (2Z,6Z)-farnesyl diphosphate lyase (cyclizing;(+)-endo-beta-bergamotene-forming); 2-cis,6-cis-Farnesyl diphosphate <=> (+)-endo-beta-Bergamotene + Diphosphate R09610 (2Z,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-gamma-cadinene-forming]; 2-cis,6-trans-Farnesyl diphosphate <=> (-)-gamma-Cadinene + Diphosphate R09611 S-adenosyl-L-methionine:tricetin 3',5'-O-dimethyltransferase; 2 S-Adenosyl-L-methionine + Tricetin <=> 2 S-Adenosyl-L-homocysteine + Tricin R09612 S-adenosyl-L-methionine:tricetin 3'-O-methyltransferase; S-Adenosyl-L-methionine + Tricetin <=> S-Adenosyl-L-homocysteine + 3'-O-Methyltricetin R09613 S-adenosyl-L-methionine:3'O-tricetin 5'-O-methyltransferase; S-Adenosyl-L-methionine + 3'-O-Methyltricetin <=> S-Adenosyl-L-homocysteine + Tricin R09614 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-alpha-barbatene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-alpha-Barbatene + Diphosphate R09615 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-cubenene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-Cubenene + Diphosphate R09616 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-delta-selinene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-delta-Selinene + Diphosphate R09617 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epicubenol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-Epicubenol + Diphosphate R09618 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3R,6E)-nerolidol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (3R,6E)-Nerolidol + Diphosphate R09619 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-gamma-bisabolene-forming]; trans,trans-Farnesyl diphosphate <=> (E)-gamma-Bisabolene + Diphosphate R09620 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming]; trans,trans-Farnesyl diphosphate <=> gamma-Bisabolene + Diphosphate R09621 malonyl-CoA:benzoyl-CoA malonyltransferase (cyclizing); 3 Malonyl-CoA + Benzoyl-CoA <=> 4 CoA + 3,5-Dihydroxybiphenyl + 4 CO2 R09622 acetyl-CoA:desacetylmycothiol N-acetyltransferase; 1-O-[2-(L-Cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + Acetyl-CoA <=> Mycothiol + CoA R09623 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(S)-beta-bisabolene-forming]; trans,trans-Farnesyl diphosphate <=> (S)-beta-Bisabolene + Diphosphate R09624 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (germacrene-C-forming); trans,trans-Farnesyl diphosphate <=> Germacrene C + Diphosphate R09625 (S)-beta-macrocarpene lyase (decyclizing); (S)-beta-Bisabolene <=> (S)-beta-Macrocarpene R09626 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming); trans,trans-Farnesyl diphosphate <=> cis-Muurola-3,5-diene + Diphosphate R09627 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming); trans,trans-Farnesyl diphosphate <=> cis-Muurola-4(14),5-diene + Diphosphate R09628 (2E,6E)-farnesyl-diphosphate diphospho-lyase [cyclising, (-)-drimenol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (-)-Drimenol + Diphosphate R09629 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming); trans,trans-Farnesyl diphosphate + H2O <=> Patchoulol + Diphosphate R09630 (2E,6E)-farnesyl-diphosphate diphosphohydrolase (presilphiperfolan-8beta-ol-forming); trans,trans-Farnesyl diphosphate + H2O <=> Presilphiperfolan-8beta-ol + Diphosphate R09631 acetyl-CoA:(3Z)-hex-3-en-1-ol acetyltransferase; Acetyl-CoA + 3-Hexenol <=> (3Z)-Hex-3-en-1-yl acetate + CoA R09632 beta-D-galactosyl-(1->4)-L-rhamnose:phosphate 1-alpha-D-galactosyltransferase; beta-D-Galactosyl-(1->4)-L-rhamnose + Orthophosphate <=> L-Rhamnose + alpha-D-Galactose 1-phosphate R09633 dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units); Dimethylallyl diphosphate + 2 Isopentenyl diphosphate <=> 2 Diphosphate + 2-cis,6-cis-Farnesyl diphosphate R09634 UDP-N-acetyl-D-glucosamine:1D-myo-inositol 3-phosphate alpha-D-glycosyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-Inositol 3-phosphate <=> 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + UDP R09635 UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase; UDP-glucuronate + Cyanidin 3-O-glucoside <=> UDP + Cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside R09636 UDP-D-glucuronate:soyasapogenol 3-O-D-glucuronosyltransferase; UDP-glucuronate + Soyasapogenol B <=> UDP + Soyasapogenol B 3-O-D-glucuronide R09637 S-adenosyl-L-methionine:fluoride adenosyltransferase; S-Adenosyl-L-methionine + Fluoride <=> 5'-Deoxy-5'-fluoroadenosine + L-Methionine R09638 dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase; Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 7-(3-Methylbut-2-enyl)-L-tryptophan R09639 S-adenosyl-L-methionine:chloride adenosyltransferase; S-Adenosyl-L-methionine + Cl- <=> 5-Deoxy-5-chloroadenosine + L-Methionine R09640 ATP:1,6-anhydro-N-acetylmuramate 6-phosphotransferase; ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetyl-beta-muramate 6-phosphate R09641 UDP-glucose:ditrans,octacis-undecaprenyl-phosphate glucose phosphotransferase; UDP-glucose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Glucopyranosyl-diphospho-ditrans,octacis-undecaprenol R09642 UDP-D-xylose:3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase; UDP-D-xylose + 3-O-alpha-D-Mannopyranosyl-alpha-D-mannopyranose <=> UMP + 3-O-(6-O-alpha-D-Xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose R09643 fluoroacetyl-CoA hydrolase; Fluoroacetyl-CoA + H2O <=> Fluoroacetate + CoA R09644 1,2-diacyl-sn-glycerol-3-diphosphate phosphohydrolase; 1,2-Diacyl-sn-glycerol 3-diphosphate + H2O <=> Phosphatidate + Orthophosphate R09645 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate + H2O <=> D-Mannose 6-phosphate + D-Glycerate R09646 N-acyl-L-homoserine-lactone amidohydrolase; N-Acyl-L-homoserine lactone + H2O <=> L-Homoserine lactone + Carboxylate R09647 (R)-piperazine-2-carboxamide amidohydrolase; (R)-Piperazine-2-carboxamide + H2O <=> (R)-Piperazine-2-carboxylate + Ammonia R09648 beta-alaninamide amidohydrolase; beta-Alaninamide + H2O <=> beta-Alanine + Ammonia R09649 (S)-piperazine-2-carboxamide amidohydrolase; (S)-Piperazine-2-carboxamide + H2O <=> (S)-Piperazine-2-carboxylate + Ammonia R09650 L-prolinamide amidohydrolase; L-Prolinamide + H2O <=> L-Proline + Ammonia R09651 1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase; 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O <=> 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + Acetate R09652 15-cis-phytoene:plastoquinone oxidoreductase; 15-cis-Phytoene + 2 Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + 2 Plastoquinol R09653 15-cis-phytoene:plastoquinone oxidoreductase; 15-cis-Phytoene + Plastoquinone <=> 15,9'-dicis-Phytofluene + Plastoquinol R09654 15,9'-dicis-phytofluene:plastoquinone oxidoreductase; 15,9'-dicis-Phytofluene + Plastoquinone <=> 9,15,9'-tricis-zeta-Carotene + Plastoquinol R09655 9,15,9'-tricis-zeta-carotene cis-trans-isomerase; 9,15,9'-tricis-zeta-Carotene <=> 9,9'-dicis-zeta-Carotene R09656 9,9'-dicis-zeta-carotene:quinone oxidoreductase; 9,9'-dicis-zeta-Carotene + Quinone <=> 7,9,9'-tricis-Neurosporene + Hydroquinone R09657 streptothricin-F hydrolase; Streptothricin F + H2O <=> Streptothricin F acid R09658 7,9,9'-tricis-neurosporene:quinone oxidoreductase; 7,9,9'-tricis-Neurosporene + Quinone <=> 7,9,7',9'-tetracis-Lycopene + Hydroquinone R09659 all-trans-zeta-carotene:acceptor oxidoreductase; all-trans-zeta-Carotene + 2 Acceptor <=> Lycopene + 2 Reduced acceptor R09660 S-methyl-5'-thioadenosine amidohydrolase; 5'-Methylthioadenosine + H2O <=> 5'-S-Methyl-5'-thioinosine + Ammonia R09661 5-nitroanthranilate aminohydrolase; 5-Nitroanthranilate + H2O <=> 5-Nitrosalicylate + Ammonia R09662 flavin:NAD+ oxidoreductase; Reduced flavin + NAD+ <=> Flavin + NADH + H+ R09663 NDP-glucose:3-phospho-D-glycerate 2-alpha-D-glucosyltransferase; NDP-glucose + 3-Phospho-D-glycerate <=> NDP + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate R09664 alpha-D-glucosyl-3-phospho-D-glycerate phosphohydrolase; 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate + H2O <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate R09665 ADP-glucose:D-glycerate 2-alpha-D-glucosyltransferase; ADP-glucose + D-Glycerate <=> 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + ADP R09666 GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase; GDP-mannose + D-Glycerate <=> GDP + 2-O-(alpha-D-Mannosyl)-D-glycerate R09667 GDP-mannose:2-O-(alpha-D-glucosyl)-3-phospho-D-glycerate 2-O-alpha-D-mannosyltransferase; GDP-mannose + 2-O-(alpha-D-Glucopyranosyl)-3-phospho-D-glycerate <=> GDP + 2-O-[2-O-(alpha-D-Mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate R09668 S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase; 5'-S-Methyl-5'-thioinosine + Orthophosphate <=> Hypoxanthine + S-Methyl-5-thio-D-ribose 1-phosphate R09669 CTP:1L-myo-inositol 1-phosphate cytidylyltransferase; CTP + 1D-myo-Inositol 3-phosphate <=> Diphosphate + CDP-1L-myo-inositol R09670 CDP-1L-myo-inositol:1L-myo-inositol 1-phosphate myo-inositolphosphotransferase; CDP-1L-myo-inositol + 1D-myo-Inositol 3-phosphate <=> CMP + Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate R09671 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating); 4,4'-Diapolycopene + 4 Reduced acceptor + 4 Oxygen <=> 4,4'-Diapolycopenedial + 4 Acceptor + 6 H2O R09672 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine N-acetylglucosaminyl hydrolase; [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine + H2O <=> [Protein]-L-serine + N-Acetyl-D-glucosamine R09673 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine N-acetylglucosaminyl hydrolase; [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine + H2O <=> [Protein]-L-threonine + N-Acetyl-D-glucosamine R09674 fumonisin B1 acylhydrolase; Fumonisin B1 + 2 H2O <=> Aminopentol + 2 Propane-1,2,3-tricarboxylate R09675 ATP:3'-dephospho-CoA 5-triphospho-alpha-D-ribosyltransferase; ATP + Dephospho-CoA <=> 2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Adenine R09676 UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase; UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-serine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine R09677 UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase; UDP-N-acetyl-alpha-D-glucosamine + [Protein]-L-threonine <=> UDP + [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine R09678 S-adenosyl-L-methionine:tricin 4'-O-methyltransferase; S-Adenosyl-L-methionine + Tricin <=> S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin R09679 S-adenosyl-L-methionine:tricetin 3',4',5'-O-trimethyltransferase; 3 S-Adenosyl-L-methionine + Tricetin <=> 3 S-Adenosyl-L-homocysteine + 3',4',5'-O-Trimethyltricetin R09680 (S)-piperidine-2-carboxamide amidohydrolase; (S)-Piperidine-2-carboxamide + H2O <=> L-Pipecolate + Ammonia R09681 ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming]; ent-Copalyl diphosphate <=> ent-Pimara-9(11),15-diene + Diphosphate R09682 9-cis-epoxycarotenoid 11,12-dioxygenase; 9-cis-Epoxycarotenoid + Oxygen <=> Xanthoxin + 12'-apo-Carotenal R09683 threo-3-hydroxy-D-aspartate ammonia-lyase (oxaloacetate-forming); threo-3-Hydroxy-D-aspartate <=> Oxaloacetate + Ammonia R09684 terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming); Terpentedienyl diphosphate <=> Terpentetriene + Diphosphate R09685 geranylgeranyl-diphosphate diphosphate-lyase (elisabethatriene-forming); Geranylgeranyl diphosphate <=> Elisabethatriene + Diphosphate R09686 (+)-copalyl-diphosphate diphosphate-lyase (phyllocladan-16alpha-ol-forming); Copalyl diphosphate + H2O <=> Phyllocladan-16alpha-ol + Diphosphate R09687 neryl-diphosphate diphosphate-lyase [cyclizing; beta-phellandrene-forming]; Neryl diphosphate <=> beta-Phellandrene + Diphosphate R09688 (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming); (S)-2,3-Epoxysqualene <=> Cucurbitadienol R09689 (S)-2,3-epoxysqualene mutase [cyclizing, (17Z)-protosta-17(20),24-dien-3beta-ol-forming]; (S)-2,3-Epoxysqualene <=> Protostadienol R09690 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diapophytoene + 4 FAD <=> 4,4'-Diapolycopene + 4 FADH2 R09691 15-cis-phytoene:acceptor oxidoreductase (neurosporene-forming); 15-cis-Phytoene + 3 Acceptor <=> all-trans-Neurosporene + 3 Reduced acceptor R09692 15-cis-phytoene:acceptor oxidoreductase; 15-cis-Phytoene + Acceptor <=> all-trans-Phytofluene + Reduced acceptor R09693 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming); 15-cis-Phytoene + 2 Acceptor <=> all-trans-zeta-Carotene + 2 Reduced acceptor R09694 1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming); 1,5-Anhydro-D-fructose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O R09695 1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one R09696 1,5-anhydro-D-fructose hydro-lyase (microthecin-forming); 1,5-Anhydro-D-fructose <=> 2-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O R09697 UDP-N-acetylglucosamine hydro-lyase (inverting; UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose-forming); UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + H2O R09698 (3R)-3-hydroxyacyl-CoA hydro-lyase; (3R)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O R09699 (8E)-9-[(1E,3E)-nona-1,3-dien-1-yloxy]non-8-enoate synthase; 9(S)-HPODE <=> Colneleate + H2O R09700 (S)-squalene-2,3-epoxide hydro-lyase (arabidiol forming); Arabidiol <=> (S)-2,3-Epoxysqualene + H2O R09701 (S)-squalene-2,3-epoxide hydro-lyase (dammarenediol-II forming); Dammarenediol-II <=> (S)-2,3-Epoxysqualene + H2O R09702 (+)-linalool hydro-lyase (myrcene-forming); (+)-Linalool <=> Myrcene + H2O R09703 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming); 15-cis-Phytoene + 5 Acceptor <=> 3,4-Dehydrolycopene + 5 Reduced acceptor R09704 D-5-monosubstituted-hydantoin racemase; D-5-Monosubstituted hydantoin <=> L-5-Monosubstituted hydantoin R09705 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose Delta3-Delta1-isomerase; 1,5-Anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose <=> 1,5-Anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose R09707 (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate isomerase; (5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate <=> (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate R09708 geraniol hydroxymutase; Geraniol <=> (+)-Linalool R09709 (S)-2,3-epoxysqualene mutase (cyclizing, thalianol-forming); (S)-2,3-Epoxysqualene <=> Thalianol R09710 (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming); (S)-2,3-Epoxysqualene <=> Germanicol R09711 (S)-2,3-epoxysqualene mutase (cyclizing, isomultiflorenol-forming); (S)-2,3-Epoxysqualene <=> Isomultiflorenol R09712 squalene mutase (cyclizing, dammara-20,24-diene-forming); Squalene <=> Dammara-20,24-diene R09713 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming); (S)-2,3-Epoxysqualene <=> Camelliol C R09714 terpentedienyl-diphosphate lyase (decyclizing); Geranylgeranyl diphosphate <=> Terpentedienyl diphosphate R09715 halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing); Geranylgeranyl diphosphate <=> Tuberculosinyl diphosphate R09716 15-cis-phytoene:acceptor oxidoreductase (lycopene-forming); 15-cis-Phytoene + 4 Acceptor <=> Lycopene + 4 Reduced acceptor R09717 threo-3-hydroxy-D-aspartate glyoxylate-lyase (glycine-forming); threo-3-Hydroxy-D-aspartate <=> Glycine + Glyoxylate R09718 D-erythro-3-hydroxyaspartate glyoxylate-lyase (glycine-forming); D-erythro-3-Hydroxyaspartate <=> Glycine + Glyoxylate R09719 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diapophytoene + FAD <=> 4,4'-Diapophytofluene + FADH2 R09720 (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate-forming]; (R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> Homoisocitrate R09721 peptidoglycan-N-acetylglucosamine amidohydrolase; Peptidoglycan(N-acetyl-D-glucosamine) + n H2O <=> Peptidoglycan-D-glucosamine + n Acetate R09722 cyanophycinase; [L-Asp(4-L-Arg)]n+1(n) + H2O <=> [L-Asp(4-L-Arg)]n(n-1) + L-Asp(4-L-Arg) R09723 beta-D-glucopyranosyl abscisate glucohydrolase; Abscisic acid glucose ester + H2O <=> D-Glucose + Abscisate R09724 trans-permethrin acylhydrolase; trans-Permethrin + H2O <=> (3-Phenoxyphenyl)methanol + (1S,3R)-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate R09725 pimeloyl-[acyl-carrier protein]-methyl-ester hydrolase; Pimeloyl-[acyl-carrier protein] methyl ester + H2O <=> Pimeloyl-[acyl-carrier protein] + Methanol R09726 ATP:molybdopterin adenylyltransferase; ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin R09727 4,4'-diaponeurosporene,AH2:oxygen 4-oxidoreductase; 4,4'-Diaponeurosporene + 2 Reduced acceptor + 2 Oxygen <=> 4,4'-Diaponeurosporen-4-al + 2 Acceptor + 3 H2O R09728 4,4'-diaponeurosporen-4-al,AH2:oxygen 4-oxidoreductase; 4,4'-Diaponeurosporen-4-al + Reduced acceptor + Oxygen <=> 4,4'-Diaponeurosporenic acid + Acceptor + H2O R09729 ATP:hygromycin-B 4-O-phosphotransferase; ATP + Hygromycin B <=> ADP + 4-O-Phosphohygromycin B R09730 geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units); Geranylgeranyl diphosphate + 7 Isopentenyl diphosphate <=> 7 Diphosphate + tritrans,heptacis-Undecaprenyl diphosphate R09731 (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 9-11 isopentenyl units); 2-cis,6-trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> n Diphosphate + trans,polycis-Polyprenyl diphosphate R09732 UDP-glucuronate:D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol beta-1,2-glucuronyltransferase; UDP-glucuronate + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> UDP + D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol R09733 GDP-mannose:D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase; GDP-mannose + D-Glc-beta-(1->4)-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> GDP + D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol R09734 GDP-mannose:GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase; GDP-mannose + D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> GDP + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol R09735 adenylyl-molybdopterin:molybdate molybdate transferase (AMP-forming); Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O R09736 S-adenosyl-L-methione:demethylmenaquinol methyltransferase; Demethylmenaquinol + S-Adenosyl-L-methionine <=> Menaquinol + S-Adenosyl-L-homocysteine R09737 S-adenosyl-L-methionine:2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol 5-C-methyltransferase; S-Adenosyl-L-methionine + 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + 6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol R09738 butanoyl-CoA:NADP+ 2,3-oxidoreductase; Butanoyl-CoA + NADP+ <=> Crotonoyl-CoA + NADPH + H+ R09739 Fe(III):ascorbate oxidorectuctase (electron-translocating); Ascorbate + Fe3+ <=> Monodehydroascorbate + Fe2+ R09740 fatty acid:hydroperoxide oxidoreductase (2-hydroxylating); Fatty acid + Hydrogen peroxide <=> alpha-Hydroxy fatty acid + H2O R09741 fatty acid:hydroperoxide oxidoreductase (RH-hydroxylating); Fatty acid + Hydrogen peroxide <=> 3-Hydroxy fatty acid + H2O R09742 cyclic alcohol:quinone oxidoreductase; Cyclic alcohol + Quinone <=> Cyclic ketone + Hydroquinone R09743 (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming); Lupan-3beta,20-diol <=> (S)-2,3-Epoxysqualene + H2O R09744 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diapophytofluene + FAD <=> 4,4'-Diapo-zeta-carotene + FADH2 R09745 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diapo-zeta-carotene + FAD <=> 4,4'-Diaponeurosporene + FADH2 R09746 4,4'-diapophytoene:FAD oxidoreductase; 4,4'-Diaponeurosporene + FAD <=> 4,4'-Diapolycopene + FADH2 R09747 beta-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase; beta-Carotene + 4 Reduced ferredoxin + 2 H+ + 2 Oxygen <=> Zeaxanthin + 4 Oxidized ferredoxin + 2 H2O R09748 FADH2:NAD+ oxidoreductase; FADH2 + NAD+ <=> FAD + NADH + H+ R09749 reduced coenzyme F420:NADP+ oxidoreductase; Reduced coenzyme F420 + NADP+ <=> Coenzyme F420 + NADPH + H+ R09750 reduced-riboflavin:NAD+ oxidoreductase; Reduced riboflavin + NAD+ <=> Riboflavin + NADH + H+ R09751 nitrite:nitrite oxidoreductase; 3 Nitrite <=> 2 Nitric oxide + Nitrate + H2O R09752 GDP:alpha-D-glucose 1-phosphate guanylyltransferase; GDP-glucose + Orthophosphate <=> D-Glucose 1-phosphate + GDP R09753 UDP-alpha-D-galactose:soyasapogenol B 3-O-glucuronide beta-D-galactosyltransferase; UDP-alpha-D-galactose + Soyasapogenol B 3-O-D-glucuronide <=> UDP + Soyasaponin III R09754 UDP-rhamnose:soyasaponin III rhamnosyltransferase; UDP-L-rhamnose + Soyasaponin III <=> UDP + Soyasaponin I R09755 UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide R09756 versicolorone:NADP+ oxidoreductase; Versicolorone + NADP+ <=> 1'-Hydroxyversicolorone + NADPH + H+ R09757 UDP-glucose:crocetin 8-O-D-glucosyltransferase; UDP-glucose + Crocetin <=> UDP + beta-D-Glucosyl crocetin R09758 UDP-glucose:beta-D-glucosylcrocetin 8'-O-D-glucosyltransferase; UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + Bis(beta-D-glucosyl) crocetin R09759 UDP-glucose:beta-D-gentiobiosylcrocetin 8'-O-D-glucosyltransferase; UDP-glucose + beta-D-Gentiobiosyl crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester R09760 phosphoenolpyruvate:D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4,6-O-(1-carboxyethan-1,1-diyl)transferase; Phosphoenolpyruvate + D-Man-beta-(1->4)-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <=> 4,6-CH3(COO-)C-D-Man-beta-(1->4)-D-GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol + Orthophosphate R09761 Castasterone <=> 26-Hydroxycastasterone R09762 Brassinolide <=> 26-Hydroxybrassinolide R09763 CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)2-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->8) glycosidic bond-forming]; KDO2-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP R09764 Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP R09765 CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)3-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->4) glycosidic bond-forming]; alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP R09766 CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)3-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->4) glycosidic bond-forming]; alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate <=> alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP R09767 ATP:(KDO)-lipid IVA 3-deoxy-alpha-D-manno-oct-2-ulopyranose 4-phosphotransferase; 3-Deoxy-D-manno-octulosonyl-lipid IV(A) + ATP <=> 4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA + ADP R09768 D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase; Sedoheptulose 7-phosphate <=> D-glycero-D-manno-Heptose 7-phosphate R09769 D-glycero-alpha-D-manno-heptose 7-phosphate aldose-ketose-isomerase; Sedoheptulose 7-phosphate <=> D-glycero-alpha-D-manno-Heptose 7-phosphate R09770 ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase; D-glycero-alpha-D-manno-Heptose 7-phosphate + ATP <=> D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + ADP R09771 D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase; D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-alpha-D-manno-Heptose 1-phosphate + Orthophosphate R09772 GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase; D-glycero-alpha-D-manno-Heptose 1-phosphate + GTP <=> GDP-D-glycero-alpha-D-manno-heptose + Diphosphate R09773 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:lipid IVA 4-amino-4-deoxy-beta-L-arabinopyranosyltransferase; Undecaprenyl phosphate alpha-L-Ara4N + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <=> Lipid IIA + di-trans,poly-cis-Undecaprenyl phosphate R09774 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:KDO2-lipid IVA 4-amino-4-deoxy-beta-L-arabinopyranosyltransferase; Undecaprenyl phosphate alpha-L-Ara4N + KDO2-lipid IVA <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid IVA + di-trans,poly-cis-Undecaprenyl phosphate R09775 LysW:L-2-aminoadipate ligase (ADP-forming); [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate:L-2-aminoadipate ligase (ADP-forming); L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate R09776 ATP:LysW-gamma-L-alpha-aminoadipate 6-phosphotransferase; LysW-gamma-L-alpha-aminoadipate + ATP <=> LysW-gamma-L-alpha-aminoadipyl 6-phosphate + ADP R09777 LysW-gamma-L-alpha-aminoadipate 6-semialdehyde:NADP+ 6-oxidoreductase (phosphorylating); LysW-gamma-L-alpha-aminoadipyl 6-phosphate + NADPH + H+ <=> LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + NADP+ + Orthophosphate R09778 LysW-gamma-L-lysine:2-oxoglutarate 6-aminotransferase; LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + L-Glutamate <=> LysW-gamma-L-lysine + 2-Oxoglutarate R09779 LysW-gamma-L-lysine amidohydrolase; LysW-gamma-L-lysine + H2O <=> L-Lysine + alpha-Aminoadipate carrier protein LysW R09780 D-arabino-hex-3-ulose-6-phosphate isomerase; D-arabino-Hex-3-ulose 6-phosphate <=> beta-D-Fructose 6-phosphate R09781 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:KDO2-lipid A 4-amino-4-deoxy-alpha-L-arabinopyranosyltransferase; KDO2-lipid A + Undecaprenyl phosphate alpha-L-Ara4N <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + di-trans,poly-cis-Undecaprenyl phosphate R09782 torulene:oxygen 4',5'-oxidoreductase (bond-cleaving); Torulene + Oxygen <=> 4'-Apo-beta,psi-caroten-4'-al + 3-Methyl-2-butenal R09783 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase; 4'-Apo-beta,psi-caroten-4'-al + NAD+ + H2O <=> Neurosporaxanthin + NADH + H+ R09784 2-oxoglutarate:oxygen oxidoreductase (decarboxylating, ethylene-forming); 2-Oxoglutarate + Oxygen <=> Ethylene + 3 CO2 + H2O R09785 L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming); L-Arginine + 2-Oxoglutarate + Oxygen <=> L-Glutamate 5-semialdehyde + Guanidine + Succinate + CO2 R09786 dimethyl sulfide,NADH:oxygen oxidoreductase; Dimethyl sulfide + Oxygen + NADH + H+ <=> Methanethiol + Formaldehyde + NAD+ + H2O R09787 arsenite:cytochrome c oxidoreductase; Arsenite + H2O + 2 Ferricytochrome c <=> Arsenate ion + 2 Ferrocytochrome c + 2 H+ R09788 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-eudesmol-forming); trans,trans-Farnesyl diphosphate + H2O <=> alpha-Eudesmol + Diphosphate R09789 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (10-epi-gamma-eudesmol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-gamma-Eudesmol + Diphosphate R09790 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming); 1,1'-Dihydroxylycopene <=> 1-Hydroxy-1,2-dihydrolycopene + H2O R09791 S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase; S-Adenosyl-L-methionine + Naringenin <=> S-Adenosyl-L-homocysteine + Sakuranetin R09792 S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase; S-Adenosyl-L-methionine + 4'-Hydroxyflavanone <=> S-Adenosyl-L-homocysteine + 4'-Methoxyflavanone R09793 presqualene-diphosphate diphosphate-lyase (15-cis-4,4'-diapophytoene-forming); Presqualene diphosphate <=> 4,4'-Diapophytoene + Diphosphate R09794 pyrrole-2-carboxylate carboxy-lyase; Pyrrole-2-carboxylate <=> Pyrrole + CO2 R09795 pyrrole-2-carboxylate carboxy-lyase; Pyrrole-2-carboxylate + H2O <=> Pyrrole + HCO3- R09796 (R)-lactate hydro-lyase; (R)-Lactate <=> Methylglyoxal + H2O R09797 N-acetyl-alpha-neuraminate 2-epimerase; N-Acetyl-alpha-neuraminate <=> N-Acetyl-beta-neuraminate R09798 nitrilotriacetate,FMNH2:oxygen oxidoreductase (glyoxylate-forming); Nitrilotriacetic acid + Reduced FMN + Oxygen <=> Iminodiacetate + Glyoxylate + FMN + H2O R09799 hydrazine:ferricytochrome-c oxidoreductase; Nitric oxide + Ammonia + 3 Ferrocytochrome c <=> Hydrazine + H2O + 3 Ferricytochrome c R09800 ectoine aminohydrolase; Ectoine + H2O <=> N(alpha)-Acetyl-L-2,4-diaminobutyrate R09801 N2-acetyl-L-2,4-diaminobutanoate amidohydrolase; N(alpha)-Acetyl-L-2,4-diaminobutyrate + H2O <=> L-2,4-Diaminobutanoate + Acetate R09802 UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase; Kaempferol + UDP-L-rhamnose <=> Afzelin + UDP R09803 UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase; Quercetin + UDP-L-rhamnose <=> Quercitrin + UDP R09804 UDP-glucose:quercitrin 7-O-glucosyltransferase; Quercitrin + UDP-glucose <=> Quercetin 3-O-rhamnoside 7-O-glucoside + UDP R09805 L-aspartate-4-semialdehyde:NAD+ oxidoreductase; L-Aspartate 4-semialdehyde + NAD+ + H2O <=> L-Aspartate + NADH + H+ R09806 raucaffrinoline:NADP+ oxidoreductase; Raucaffrinoline + NADP+ <=> Perakine + NADPH + H+ R09807 prosolanapyrone-II:oxygen 3'-oxidoreductase; Prosolanapyrone II + Oxygen <=> Prosolanapyrone III + Hydrogen peroxide R09808 Nitric oxide + Azide <=> Nitrous oxide + Nitrogen R09809 Nitric oxide + Ammonia <=> Nitrous oxide + H2O R09810 alpha-linolenate:oxygen (9R)-oxidoreductase; (9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (9R,10E,12Z,15Z)-9-Hydroperoxyoctadeca-10,12,15-trienoate R09811 linoleate:oxygen (10R)-oxidoreductase; Linoleate + Oxygen <=> (8E,10R,12Z)-10-Hydroperoxy-8,12-octadecadienoate R09812 pentalenene,reduced ferredoxin:oxygen 13-oxidoreductase; Pentalenene + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pentalen-13-ol + 2 Oxidized ferredoxin + H2O R09813 pentalen-13-ol,reduced ferredoxin:oxygen 13-oxidoreductase; Pentalen-13-ol + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Pentalen-13-al + 2 Oxidized ferredoxin + 2 H2O R09814 pentalenene,reduced ferredoxin:oxygen 13-oxidoreductase; Pentalenene + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Pentalen-13-al + 4 Oxidized ferredoxin + 3 H2O R09815 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11alpha-Hydroxy-beta-amyrin + H2O + [Oxidized NADPH---hemoprotein reductase] R09816 11alpha-hydroxy-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen 11-oxidoreductase; 11alpha-Hydroxy-beta-amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Oxo-beta-amyrin + 2 H2O + [Oxidized NADPH---hemoprotein reductase] R09817 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); beta-Amyrin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Oxo-beta-amyrin + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase] R09818 1-hydroxy-2-naphthoate,NADPH:oxygen oxidoreductase (2-hydroxylating, decarboxylating); 1-Hydroxy-2-naphthoate + NADPH + H+ + Oxygen <=> Naphthalene-1,2-diol + NADP+ + H2O + CO2 R09819 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione,FMNH2:oxygen oxidoreductase; 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + Reduced FMN + Oxygen <=> 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O R09820 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde:NADP+ oxidoreductase; 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP+ + H2O <=> 3-Oxo-5,6-dehydrosuberyl-CoA + NADPH + H+ R09821 S-adenosyl-L-methionine:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N,N-dimethyltransferase; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-methionine <=> dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-homocysteine R09822 S-adenosyl-L-methionine:mycinamicin VI 2''-O-methyltransferase; Mycinamicin VI + S-Adenosyl-L-methionine <=> Mycinamicin III + S-Adenosyl-L-homocysteine R09823 S-adenosyl-L-methionine:mycinamicin III 3''-O-methyltransferase; Mycinamicin III + S-Adenosyl-L-methionine <=> Mycinamicin IV + S-Adenosyl-L-homocysteine R09824 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose:2-oxoglutarate aminotransferase; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate R09825 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine:2-oxoglutarate aminotransferase; UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-Oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate R09826 all-trans-retinyl ester acylhydrolase, 13-cis retinol forming; Retinyl ester + H2O <=> 13-cis-Retinol + Fatty acid R09827 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase; Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate R09830 L-tyrosine:NAD+ oxidoreductase (deaminating); L-Tyrosine + H2O + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + Ammonia + NADH + H+ R09831 beta-D-4-deoxy-Delta4-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp beta-D-4-deoxy-Delta4-GlcAp hydrolase; beta-D-4-Deoxy-Delta4-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc R09832 8-oxo-dGTP diphosphohydrolase; 8-Oxo-dGTP + H2O <=> 8-Oxo-dGMP + Diphosphate R09833 2-hydroxy-dATP diphosphohydrolase; 2-Hydroxy-dATP + H2O <=> 2-Hydroxy-dAMP + Diphosphate R09834 UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose hydrolase; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + H2O <=> 2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + UDP R09835 (+)-beta-caryophyllene hydrolase [cyclizing, (+)-caryolan-1-ol-forming]; (+)-beta-Caryophyllene + H2O <=> (+)-Caryolan-1-ol R09836 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolyase; 2-Oxepin-2(3H)-ylideneacetyl-CoA + H2O <=> 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde R09837 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase; 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA <=> 2-Oxepin-2(3H)-ylideneacetyl-CoA R09838 phenylacetyl-CoA:oxygen oxidoreductase (1,2-epoxidizing); Phenylacetyl-CoA + Oxygen + NADPH + H+ <=> 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+ R09839 2,3-didehydroadipoyl-CoA:acetyl-CoA C-didehydroadipoyltransferase (double bond migration); 3-Oxo-5,6-dehydrosuberyl-CoA + CoA <=> 5-Carboxy-2-pentenoyl-CoA + Acetyl-CoA R09840 Phenylacetyl-CoA + H2O <=> Phenylacetic acid + CoA R09841 phosphoenolpyruvate:2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose transferase (phosphate-hydrolysing, 2,7-acetylamino-transfering, 2-carboxy-2-oxoethyl-forming); 2,4-Bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + Phosphoenolpyruvate + H2O <=> Pseudaminic acid + Orthophosphate R09842 acetyl-CoA:UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine 4-N-acetyltransferase; UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + Acetyl-CoA <=> UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose + CoA R09843 CTP:pseudaminate cytidylyltransferase; Pseudaminic acid + CTP <=> CMP-pseudaminic acid + Diphosphate R09844 farnesyl-diphosphate:protein-cysteine farnesyltransferase; trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate R09845 CAAX protease; S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide R09846 prenylcycteine methylesterase; Protein C-terminal S-farnesyl-L-cysteine + Methanol <=> Protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O R09847 Protein C-terminal S-farnesyl-L-cysteine methyl ester <=> Farnesylcysteine R09848 farnesal reductase; 2-trans,6-trans-Farnesal <=> (2E,6E)-Farnesol R09849 CTP:2-trans,6-trans-farnesol O-phosphotransferase; (2E,6E)-Farnesol + CTP <=> trans,trans-Farnesyl phosphate + CDP R09850 CTP:farnesyl-phosphate phosphotransferase; trans,trans-Farnesyl phosphate + CTP <=> trans,trans-Farnesyl diphosphate + CDP R09851 Proansamitocin <=> 19-Chloroproansamitocin R09852 19-Chloroproansamitocin <=> 20-O-Methyl-19-chloroproansamitocin R09853 carbamoyl-phosphate:20-O-methyl-19-chloroproansamitocin carbamoyltransferase; 20-O-Methyl-19-chloroproansamitocin + Carbamoyl phosphate <=> N-Demethyl-desepoxymaytansinol + Orthophosphate R09854 N-Demethyl-desepoxymaytansinol + 2-Methylpropanoyl-CoA <=> N-Demethyl-desepoxyansamitocin P-3 + CoA R09855 N-Demethyl-desepoxyansamitocin P-3 <=> N-Demethylansamitocin P-3 R09856 S-adenosyl-L-methionine:N-demethylansamitocin-P-3 N-methyltransferase; S-Adenosyl-L-methionine + N-Demethylansamitocin P-3 <=> S-Adenosyl-L-homocysteine + Ansamitocin P-3 R09857 UDP-glucose:N-demethylansamitocin-P-3 beta-D-glucosyltransferase; UDP-glucose + N-Demethylansamitocin P-3 <=> UDP + Ansamitocinoside P-3 R09858 carbamoyl-phosphate:ansamitocinoside-P-3 carbamoyltransferase; Ansamitocinoside P-3 + Carbamoyl phosphate <=> 4''-O-Carbamoyl ansamitocinoside P-3 + Orthophosphate R09859 cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); Cholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> (25S)-26-Hydroxycholest-4-en-3-one + 2 Oxidized ferredoxin + H2O R09860 androsta-1,4-diene-3,17-dione,[reduced ferredoxin]:oxygen oxidoreductase (9alpha-hydroxylating); Androsta-1,4-diene-3,17-dione + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 9alpha-Hydroxyandrosta-1,4-diene-3,17-dione + 2 Oxidized ferredoxin + H2O R09861 ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; ent-Isokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha-Hydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase] R09862 9beta-pimara-7,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen 19-oxidoreductase; 9beta-Pimara-7,15-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R09863 9beta-pimara-7,15-dien-19-ol,[reduced NADPH---hemoprotein reductase]:oxygen 19-oxidoreductase; 9beta-Pimara-7,15-dien-19-ol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09864 9beta-pimara-7,15-dien-19-al,[reduced NADPH---hemoprotein reductase]:oxygen 19-oxidoreductase; 9beta-Pimara-7,15-dien-19-al + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-oate + [Oxidized NADPH---hemoprotein reductase] + H2O R09865 9beta-pimara-7,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen 19-oxidoreductase; 9beta-Pimara-7,15-diene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 9beta-Pimara-7,15-dien-19-oate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R09866 ent-cassa-12,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen 11-oxidoreductase; ent-Cassa-12,15-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-11beta-Hydroxycassa-12,15-diene + [Oxidized NADPH---hemoprotein reductase] + H2O R09867 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl-acetate,NADPH:oxygen 14-oxidoreductase; Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol + Oxygen + NADPH + H+ <=> 10beta,14beta-Dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O R09868 taxusin,[reduced NADPH---hemoprotein reductase]:oxygen 7-oxidoreductase; Taxusin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7beta-Hydroxytaxusin + [Oxidized NADPH---hemoprotein reductase] + H2O R09870 S-adenosyl-L-methionine:trans-resveratrol 3-O-methyltransferase; S-Adenosyl-L-methionine + Resveratrol <=> S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene R09871 S-adenosyl-L-methionine:3-methoxy-4',5-dihydroxy-trans-stilbene 5-O-methyltransferase; S-Adenosyl-L-methionine + 3-Methoxy-4',5-dihydroxy-trans-stilbene <=> S-Adenosyl-L-homocysteine + Pterostilbene R09872 S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase; 2 S-Adenosyl-L-methionine + Resveratrol <=> 2 S-Adenosyl-L-homocysteine + Pterostilbene R09873 acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase; Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose R09874 geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming]; Geranylgeranyl diphosphate + H2O <=> (13E)-Labda-7,13-dien-15-ol + Diphosphate R09875 leukotriene-C4 hydrolase; Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate R09876 8-oxoguanine aminohydrolase; 8-Oxoguanine + H2O <=> Urate + Ammonia R09877 8-oxo-dGDP phosphohydrolase; 8-Oxo-dGDP + H2O <=> 8-Oxo-dGMP + Orthophosphate R09879 P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (ATP-forming); P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> 2 ATP R09880 P1,P5-bis(5'-adenosyl)pentaphosphate nucleotidohydrolase (ATP-forming); Bis(5'-adenosyl) pentaphosphate + H2O <=> ATP + ADP R09881 P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (AMP-forming); P1,P6-Bis(5'-adenosyl)hexaphosphate + H2O <=> Adenosine 5'-pentaphosphate + AMP R09882 P1,P5-bis(5'-adenosyl)pentaphosphate nucleotidohydrolase (AMP-forming); Bis(5'-adenosyl) pentaphosphate + H2O <=> Adenosine tetraphosphate + AMP R09883 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase ( (2Z,4Z)-2-hydroxyhexa-2,4-dienoate-forming); 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate R09884 androstenedione:acceptor Delta1-oxidoreductase; Androstenedione + Acceptor <=> Androsta-1,4-diene-3,17-dione + Reduced acceptor R09885 9alpha-Hydroxyandrosta-1,4-diene-3,17-dione <=> 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione R09886 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (7-epi-alpha-selinene-forming); trans,trans-Farnesyl diphosphate <=> 7-epi-alpha-Selinene + Diphosphate R09887 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-guaiene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Guaiene + Diphosphate R09888 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (viridiflorene-forming); trans,trans-Farnesyl diphosphate <=> Viridiflorene + Diphosphate R09889 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-beta-caryophyllene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-beta-Caryophyllene + Diphosphate R09890 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 5-epi-alpha-selinene-forming); trans,trans-Farnesyl diphosphate <=> 5-epi-alpha-Selinene + Diphosphate R09891 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, cubebol-forming); trans,trans-Farnesyl diphosphate + H2O <=> Cubebol + Diphosphate R09892 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-gamma-cadinene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-gamma-Cadinene + Diphosphate R09893 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, delta-guaiene-forming); trans,trans-Farnesyl diphosphate <=> delta-Guaiene + Diphosphate R09894 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, gamma-curcumene-forming); trans,trans-Farnesyl diphosphate <=> gamma-Curcumene + Diphosphate R09895 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-cuprenene-forming]; trans,trans-Farnesyl diphosphate <=> (-)-alpha-Cuprenene + Diphosphate R09896 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, avermitilol-forming); trans,trans-Farnesyl diphosphate + H2O <=> Avermitilol + Diphosphate R09897 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-delta-cadinene-forming]; trans,trans-Farnesyl diphosphate <=> (-)-delta-Cadinene + Diphosphate R09898 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-T-muurolol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-T-Muurolol + Diphosphate R09899 9alpha-copalyl-diphosphate diphosphate-lyase [(12E)-9alpha-labda-8(17),12,14-triene-forming]; 9alpha-Copalyl diphosphate <=> (12E)-9alpha-Labda-8(17),12,14-triene + Diphosphate R09900 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming); trans,trans-Farnesyl diphosphate <=> Bicyclogermacrene + Diphosphate R09901 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (7-epi-sesquithujene-forming); trans,trans-Farnesyl diphosphate <=> 7-epi-Sesquithujene + Diphosphate R09902 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (sesquithujene-forming); trans,trans-Farnesyl diphosphate <=> Sesquithujene + Diphosphate R09903 ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-isokaurene-forming); ent-Copalyl diphosphate <=> ent-Isokaurene + Diphosphate R09904 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose isomerase; dTDP-4-oxo-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose R09905 (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate hydroxymutase [(5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate-forming]; 8(R)-HPODE <=> 5S,8R-DiHODE R09906 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, shionone-forming); (S)-2,3-Epoxysqualene <=> Shionone R09907 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, parkeol-forming); (S)-2,3-Epoxysqualene <=> Parkeol R09908 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, achilleol-B-forming); (S)-2,3-Epoxysqualene <=> Achilleol B R09909 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming); (S)-2,3-Epoxysqualene <=> Glutinol R09910 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, friedelin-forming); (S)-2,3-Epoxysqualene <=> Friedelin R09911 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baccharis-oxide-forming); (S)-2,3-Epoxysqualene <=> Baccharis oxide R09912 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-seco-amyrin-forming); (S)-2,3-Epoxysqualene <=> alpha-seco-Amyrin R09913 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, marneral-forming); (S)-2,3-Epoxysqualene <=> Marneral R09914 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, beta-seco-amyrin-forming); (S)-2,3-Epoxysqualene <=> beta-seco-Amyrin R09915 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, delta-amyrin-forming); (S)-2,3-Epoxysqualene <=> delta-Amyrin R09916 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, tirucalla-7,24-dien-3beta-ol-forming); (S)-2,3-Epoxysqualene <=> Tirucalla-7,24-dien-3beta-ol R09917 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming); (S)-2,3-Epoxysqualene <=> Baruol R09918 (-)-solanapyrone-A lyase (decyclizing); Prosolanapyrone III <=> (-)-Solanapyrone A R09919 Delta4-Dafachronic acid <=> Androstenedione R09920 cholesterol:NAD+ 3-oxidoreductase; cholest-4-en-3-one delta5-delat4-isomerase; Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+ R09921 stemod-13(17)-ene,[reduced NADPH---hemoprotein reductase]:oxygen 19-oxidoreductase; Stemod-13(17)-ene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> syn-Stemoden-19-oate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R09922 (+)-linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); (+)-Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Hydroxylinalool + [Oxidized NADPH---hemoprotein reductase] + H2O R09923 (-)-linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); (-)-Linalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Hydroxylinalool + [Oxidized NADPH---hemoprotein reductase] + H2O R09924 8-hydroxylinalool,[reduced NADPH---hemoprotein reductase]:oxygen 8-oxidoreductase; (6E)-8-Hydroxylinalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (6E)-8-Oxolinalool + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R09925 linalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); Linalool + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> (6E)-8-Oxolinalool + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R09926 (6E)-8-hydroxygeraniol:NADP+ oxidoreductase; (6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Hydroxygeranial + NADPH + H+ R09927 (6E)-8-hydroxygeranial:NADP+ oxidoreductase; (6E)-8-Hydroxygeranial + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+ R09928 (6E)-8-hydroxygeraniol:NADP+ oxidoreductase; (6E)-8-Hydroxygeraniol + NADP+ <=> (6E)-8-Oxogeraniol + NADPH + H+ R09929 (6E)-8-oxogeraniol:NADP+ oxidoreductase; (6E)-8-Oxogeraniol + NADP+ <=> (6E)-8-Oxogeranial + NADPH + H+ R09930 eugenol:NADP+ oxidoreductase (coniferyl ester reducing); Eugenol + Carboxylate + NADP+ <=> Coniferyl ester + NADPH + H+ R09931 eugenol:NADP+ oxidoreductase (coniferyl acetate reducing); Isoeugenol + Acetate + NADP+ <=> Coniferyl acetate + NADPH + H+ R09932 (S)-benzoin:NADP+ oxidoreductase; (S)-Benzoin + NADP+ <=> Benzil + NADPH + H+ R09933 (R)-benzoin:NADP+ oxidoreductase; (R)-Benzoin + NADP+ <=> Benzil + NADPH + H+ R09934 alpha-humulene,[reduced NADPH---hemoprotein reductase]:oxygen 10-oxidoreductase; Humulene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 10-Hydroxy-alpha-humulene + [Oxidized NADPH---hemoprotein reductase] + H2O R09935 (+)-sabinene,NADPH:oxygen oxidoreductase (3-hydroxylating); (+)-Sabinene + NADPH + H+ + Oxygen <=> (+)-cis-Sabinol + NADP+ + H2O R09936 uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening); Uracil + Reduced FMN + Oxygen <=> (Z)-3-Ureidoacrylate peracid + FMN R09937 thymine,FMNH2:oxygen oxidoreductase (thymine hydroxylating, ring-opening); Thymine + Reduced FMN + Oxygen <=> (Z)-2-Methylureidoacrylate peracid + FMN R09938 lupanine:cytochrome c-oxidoreductase (17-hydroxylating); Lupanine + 2 Ferricytochrome c + H2O <=> 17-Hydroxylupanine + 2 Ferrocytochrome c + 2 H+ R09939 S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate 3-methyltransferase; S-Adenosyl-L-methionine + 5-Guanidino-2-oxopentanoate <=> S-Adenosyl-L-homocysteine + (3R)-5-Guanidino-3-methyl-2-oxopentanoate R09940 S-adenosyl-L-methionine:geranyl-diphosphate 2-C-methyltransferase; S-Adenosyl-L-methionine + Geranyl diphosphate <=> S-Adenosyl-L-homocysteine + (E)-2-Methylgeranyl diphosphate R09941 3-O-alpha-D-glucopyranosyl-D-glucopyranose:phosphate beta-D-glucosyltransferase; Nigerose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate R09942 N,N'-diacetylchitobiose:phosphate N-acetyl-D-glucosaminyltransferase; Chitobiose + Orthophosphate <=> N-Acetyl-D-glucosamine + N-Acetyl-alpha-D-glucosamine 1-phosphate R09943 4-O-beta-D-mannopyranosyl-D-glucopyranose:phosphate alpha-D-mannosyltransferase; 4-O-beta-D-Mannopyranosyl-D-glucopyranose + Orthophosphate <=> D-Glucose + D-Mannose 1-phosphate R09944 CTP:1,2-diacyl-sn-glycerol 3-phosphotransferase; CTP + 1,2-Diacyl-sn-glycerol <=> CDP + Phosphatidate R09945 ATP:alpha-maltose 1-phosphotransferase; ATP + Maltose <=> ADP + alpha-Maltose 1-phosphate R09946 ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase; ATP + UDP-N-acetyl-alpha-D-glucosamine <=> ADP + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate R09947 (Z)-3-ureidoacrylate-peracid amidohydrolase; (Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + Carbamate R09948 (Z)-3-ureidoacrylate peracid amidohydrolase; (Z)-3-Ureidoacrylate peracid + H2O <=> (Z)-3-Peroxyaminoacrylate + CO2 + Ammonia R09949 (Z)-2-methylureidoacrylate-peracid amidohydrolase; (Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + Carbamate R09950 (Z)-2-methylureidoacrylate peracid amidohydrolase; (Z)-2-Methylureidoacrylate peracid + H2O <=> (Z)-2-Methylperoxyaminoacrylate + CO2 + Ammonia R09951 1D-chiro-inositol:NAD+ oxidoreductase; 1D-chiro-Inositol + NAD+ <=> 1-Keto-D-chiro-inositol + NADH + H+ R09952 2,4,6/3,5-pentahydroxycyclohexanone 2-isomerase; 1-Keto-D-chiro-inositol <=> 2,4,6/3,5-Pentahydroxycyclohexanone R09953 scyllo-inositol:NAD+ oxidoreductase; scyllo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+ R09954 scyllo-inositol:NADP+ oxidoreductase; scyllo-Inositol + NADP+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADPH + H+ R09955 5-androstene-3,17-dione delta5-delta4-isomerase; 5-Androstene-3,17-dione <=> Androstenedione R09956 epiandrosterone:NAD+ oxidoreductase; Epiandrosterone + NAD+ <=> 5alpha-Androstane-3,17-dione + NADH + H+ R09957 dehydroepiandrosterone:NAD+ oxidoreductase; Dehydroepiandrosterone + NAD+ <=> 5-Androstene-3,17-dione + NADH + H+ R09958 (S)-ethylmalonyl-CoA carboxy-lyase (butanoyl-CoA-forming); (2S)-Ethylmalonyl-CoA <=> Butanoyl-CoA + CO2 R09959 7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming); 7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 6-Carboxy-5,6,7,8-tetrahydropterin + Acetaldehyde + Triphosphate R09960 4-hydroxy-2-oxohexanoate hydro-lyase [(2Z,4Z)-2-hydroxyhexa-2,4-dienoate-forming]; 4-Hydroxy-2-oxohexanoic acid <=> (2Z,4Z)-2-Hydroxyhexa-2,4-dienoate + H2O R09961 geranyl-diphosphate diphosphate-lyase (cyclizing; tricyclene-forming); Geranyl diphosphate <=> Tricyclene + Diphosphate R09962 geranyl-diphosphate diphosphate-lyase [(E)-beta-ocimene-forming]; Geranyl diphosphate <=> (E)-beta-Ocimene + Diphosphate R09963 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-car-3-ene-forming]; Geranyl diphosphate <=> (+)-3-Carene + Diphosphate R09964 geranyl-diphosphate diphosphate-lyase (cyclizing, 1,8-cineole-forming); Geranyl diphosphate + H2O <=> 1,8-Cineole + Diphosphate R09965 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-sabinene-forming]; Geranyl diphosphate <=> (-)-Sabinene + Diphosphate R09966 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-sabinene-forming]; Geranyl diphosphate <=> (+)-Sabinene + Diphosphate R09967 geranylgeranyl-diphosphate hydratase (copal-8-ol-diphosphate-forming); copal-8-ol-diphosphate hydro-lyase; Copal-8-ol diphosphate <=> Geranylgeranyl diphosphate + H2O R09968 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-alpha-terpineol-forming]; Geranyl diphosphate + H2O <=> (R)-(+)-alpha-Terpineol + Diphosphate R09969 geranyl-diphosphate diphosphate-lyase (cyclizing, gamma-terpinene-forming); Geranyl diphosphate <=> gamma-Terpinene + Diphosphate R09970 geranyl-diphosphate diphosphate-lyase (cyclizing, alpha-terpinene-forming); Geranyl diphosphate <=> alpha-Terpinene + Diphosphate R09971 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-camphene-forming]; Geranyl diphosphate <=> (+)-Camphene + Diphosphate R09972 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-camphene-forming]; Geranyl diphosphate <=> (-)-Camphene + Diphosphate R09973 (E)-2-methylgeranyl-diphosphate diphosphate-lyase (cyclizing, 2-methylisoborneol-forming); (E)-2-Methylgeranyl diphosphate + H2O <=> 2-Methylisoborneol + Diphosphate R09974 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-alpha-pinene-forming]; Geranyl diphosphate <=> (+)-alpha-Pinene + Diphosphate R09975 geranyl-diphosphate diphosphate-lyase [(+)-beta-pinene-forming]; Geranyl diphosphate <=> (+)-beta-Pinene + Diphosphate R09976 (2E,6E)-farnesyl diphosphate diphosphate-lyase (cyclizing, beta-sesquiphellandrene-forming); trans,trans-Farnesyl diphosphate <=> beta-Sesquiphellandrene + Diphosphate R09977 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate isomerase; 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate R09978 7-carboxy-7-carbaguanine:ammonia ligase (ADP-forming); 7-Carboxy-7-carbaguanine + Ammonia + ATP <=> 7-Cyano-7-carbaguanine + ADP + Orthophosphate + H2O R09979 (2S)-ethylmalonyl-CoA epimerase; (2S)-Ethylmalonyl-CoA <=> (2R)-Ethylmalonyl-CoA R09980 ureidoacrylate amidohydrolase; Ureidoacrylate + H2O <=> Aminoacrylate + Carbamate R09981 (Z)-3-Ureidoacrylate peracid + NADH + H+ <=> Ureidoacrylate + NAD+ + H2O R09982 (Z)-3-Peroxyaminoacrylate <=> Aminoacrylate R09983 Aminoacrylate + H2O <=> 3-Oxopropanoate + Ammonia R09984 (-)-endo-fenchol:NAD+ oxidoreductase; (-)-endo-Fenchol + NAD+ <=> (1S,4R)-(+)-Fenchone + NADH + H+ R09985 (-)-endo-fenchol:NADP+ oxidoreductase; (-)-endo-Fenchol + NADP+ <=> (1S,4R)-(+)-Fenchone + NADPH + H+ R09986 (+)-thujan-3-ol:NAD+ oxidoreductase; (+)-Thujan-3-ol + NAD+ <=> (+)-Thujan-3-one + NADH + H+ R09987 (+)-thujan-3-ol:NADP+ oxidoreductase; (+)-Thujan-3-ol + NADP+ <=> (+)-Thujan-3-one + NADPH + H+ R09988 10-hydroxy-alpha-humulene:NAD+ oxidoreductase; 10-Hydroxy-alpha-humulene + NAD+ <=> Zerumbone + NADH + H+ R09989 L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase; L-threo-7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+ R09990 L-threo-tetrahydrobiopterin:NADP+ oxidoreductase; L-threo-Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H+ R09991 peptidyl-glutamate 4-carboxylase (menaquinone-epoxidizing); 2,3-Epoxymenaquinone + Gla protein + H2O <=> Menaquinol + Gla protein precursor + CO2 + Oxygen R09992 menaquinone:oxidized-dithiothreitol oxidoreductase; 2,3-Epoxymenaquinone + Dithiothreitol <=> Menaquinone + Oxidized dithiothreitol + H2O R09993 4-amino-5-aminomethyl-2-methylpyrimidine aminohydrolase; 4-Amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + Ammonia R09994 alpha-maltose 1-phosphate:(1->4)-alpha-D-glucan 4-alpha-D-maltosyltransferase; alpha-Maltose 1-phosphate + Amylose(n) <=> Orthophosphate + Amylose(n+2) R09995 Starch <=> alpha,alpha-Trehalose R09996 2 Nitric oxide <=> Nitrogen + Oxygen R09997 methanethiol:coenzyme M methyltransferase; Methanethiol + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Hydrogen sulfide R09998 methylamine:coenzyme M methyltransferase; Methylamine + Coenzyme M <=> Ammonia + 2-(Methylthio)ethanesulfonate R09999 dimethylamine:coenzyme M methyltransferase; Dimethylamine + Coenzyme M <=> 2-(Methylthio)ethanesulfonate + Methylamine R10000 [methyl-Co(III) corrinoid protein]:coenzyme M methyltransferase; Coenzyme M + Methyl-Co(III) corrinoid protein <=> 2-(Methylthio)ethanesulfonate + Co(I) corrinoid protein R10001 methanethiol:[Co(I) corrinoid protein] Co-methyltransferase; Methanethiol + Co(I) corrinoid protein <=> Hydrogen sulfide + Methyl-Co(III) corrinoid protein R10002 6-carboxy-5,6,7,8-tetrahydropterin ammonia-lyase; 6-Carboxy-5,6,7,8-tetrahydropterin <=> 7-Carboxy-7-carbaguanine + Ammonia R10003 [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate:CoA ligase (AMP-forming); [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA <=> AMP + Diphosphate + [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA R10004 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-muurolene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Muurolene + Diphosphate R10005 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, gamma-muurolene-forming); trans,trans-Farnesyl diphosphate <=> gamma-Muurolene + Diphosphate R10006 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, beta-copaene-forming); trans,trans-Farnesyl diphosphate <=> beta-Copaene + Diphosphate R10007 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, beta-cubebene-forming); trans,trans-Farnesyl diphosphate <=> beta-Cubebene + Diphosphate R10008 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-sativene-forming); trans,trans-Farnesyl diphosphate <=> (+)-Sativene + Diphosphate R10009 all-trans-heptaprenyl-diphosphate diphosphate-lyase (cyclizing, tetraprenyl-beta-curcumene-forming); all-trans-Heptaprenyl diphosphate <=> Tetraprenyl-beta-curcumene + Diphosphate R10010 L-lysine carboxy-aminomethylmutase; L-Lysine <=> (2R,3R)-3-Methylornithine R10011 L-Lysine + (2R,3R)-3-Methylornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + Products of ATP breakdown R10012 (2R,3R)-3-Methylornithinyl-N6-lysine + NAD+ + H2O <=> (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine + Ammonia + NADH + H+ R10013 (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine <=> L-Pyrrolysine + H2O R10014 methylamine:[Co(I) corrinoid protein] Co-methyltransferase; Methylamine + Co(I) corrinoid protein <=> Ammonia + Methyl-Co(III) corrinoid protein R10015 dimethylamine:[Co(I) corrinoid protein] Co-methyltransferase; Dimethylamine + Co(I) corrinoid protein <=> Methylamine + Methyl-Co(III) corrinoid protein R10016 trimethylamine:[Co(I) corrinoid protein] Co-methyltransferase; Trimethylamine + Co(I) corrinoid protein <=> Dimethylamine + Methyl-Co(III) corrinoid protein R10017 tetramethylammonium:[Co(I) corrinoid protein] Co-methyltransferase; Tetramethylammonium + Co(I) corrinoid protein <=> Trimethylamine + Methyl-Co(III) corrinoid protein R10018 Papaveroxine <=> Narcotine hemiacetal R10020 narcotine hemiacetal:NAD+ 1-oxidoreductase; Narcotine hemiacetal + NAD+ <=> alpha-Narcotine + NADH + H+ R10021 5-exo-hydroxycamphor:NAD+ oxidoreductase; (+)-exo-5-Hydroxycamphor + NAD+ <=> (+)-Bornane-2,5-dione + NADH + H+ R10022 5-Oxo-1,2-campholide <=> [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate R10023 amorpha-4,11-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Amorpha-4,11-diene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinic alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O R10024 artemisinic-alcohol,[reduced NADPH---hemoprotein reductase]:oxygen 12-oxidoreductase; Artemisinic alcohol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinic aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10025 artemisinic-aldehyde,[reduced NADPH---hemoprotein reductase]:oxygen 12-oxidoreductase; Artemisinic aldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Artemisinate + [Oxidized NADPH---hemoprotein reductase] + H2O R10026 amorpha-4,11-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Amorpha-4,11-diene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Artemisinate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R10027 L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O R10028 N-hydroxy-L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); N-Hydroxy-L-isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O R10029 N,N-Dihydroxy-L-isoleucine <=> (E)-2-Methylbutanal oxime + CO2 + H2O R10030 (E)-2-Methylbutanal oxime <=> (Z)-2-Methylbutanal oxime R10031 L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O R10032 N-hydroxy-L-valine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); N-Hydroxy-L-valine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-valine + [Oxidized NADPH---hemoprotein reductase] + H2O R10033 N,N-Dihydroxy-L-valine <=> (E)-2-Methylpropanal oxime + CO2 + H2O R10034 (E)-2-Methylpropanal oxime <=> (Z)-2-Methylpropanal oxime R10035 beta-D-glucoside glucohydrolase; Dhurrin + H2O <=> (S)-4-Hydroxymandelonitrile + beta-D-Glucose R10036 (Z)-2-Methylbutanal oxime + NADPH + H+ + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O R10037 UDP-glucose:(2R)-2-hydroxy-2-methylbutanenitrile beta-D-glucosyltransferase; (2R)-2-Hydroxy-2-methylbutanenitrile + UDP-glucose <=> UDP + Lotaustralin R10038 (Z)-2-Methylpropanal oxime + NADPH + H+ + Oxygen <=> Acetone cyanohydrin + NADP+ + 2 H2O R10039 beta-D-glucoside glucohydrolase; Lotaustralin + H2O <=> (2R)-2-Hydroxy-2-methylbutanenitrile + beta-D-Glucose R10040 beta-D-glucoside glucohydrolase; Linamarin + H2O <=> Acetone cyanohydrin + beta-D-Glucose R10041 (E)-Phenylacetaldoxime <=> (Z)-Phenylacetaldehyde oxime R10042 benzene,NADH:oxygen oxidoreductase; Benzene + Oxygen + NADH + H+ <=> Phenol + NAD+ + H2O R10043 phenol,NADH:oxygen oxidoreductase (2-hydroxylating); Phenol + Oxygen + NADH + H+ <=> Catechol + NAD+ + H2O R10044 [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA,NADPH:oxygen oxidoreductase (1,5-lactonizing); [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + Oxygen + NADPH + H+ <=> [(2R)-3,3,4-Trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O R10045 (+)-camphor,NADPH:oxygen oxidoreductase (6-exo-hydroxylating); (+)-Camphor + NADPH + H+ + Oxygen <=> (+)-6-exo-Hydroxycamphor + NADP+ + H2O R10046 nicotinate D-ribonucleoside ribohydrolase; Nicotinate D-ribonucleoside + H2O <=> Nicotinate + D-Ribose R10047 (+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (6-endo-hydroxylating); (+)-Camphor + Reduced putidaredoxin + Oxygen <=> (+)-6-endo-Hydroxycamphor + Oxidized putidaredoxin + H2O R10048 putidaredoxin:NAD+ oxidoreductase; Reduced putidaredoxin + NAD+ <=> Oxidized putidaredoxin + NADH + H+ R10049 2-oxopropanal:D-fructose 1,6-bisphosphate glycerone-phosphotransferase; Methylglyoxal + D-Fructose 1,6-bisphosphate <=> D-Glyceraldehyde 3-phosphate + 6-Deoxy-5-ketofructose 1-phosphate R10050 2-oxopropanal:D-fructose 1-phosphate glycerone-phosphotransferase; Methylglyoxal + D-Fructose 1-phosphate <=> D-Glyceraldehyde + 6-Deoxy-5-ketofructose 1-phosphate R10051 bornane-2,6-dione hydrolase; Bornane-2,6-dione + H2O <=> [(1S)-4-Hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate R10052 (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase; (2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+ R10053 L-gulono-1,4-lactone:oxygen 3-oxidoreductase; L-Gulono-1,4-lactone + Oxygen <=> Ascorbate + Hydrogen peroxide R10054 L-lysine:NAD+ 6-oxidoreductase (deaminating); L-Lysine + NAD+ <=> (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia R10055 violaxanthin:ascorbate oxidoreductase; Violaxanthin + 2 Ascorbate <=> Zeaxanthin + 2 Dehydroascorbate + 2 H2O R10056 protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6,N6-dimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein lysine + 2 Succinate + 2 Formaldehyde + 2 CO2 R10057 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O R10059 L-tyrosine,iodide:NADP+ oxidoreductase (iodinating); L-Tyrosine + 2 NADP+ + 2 Iodide <=> 3,5-Diiodo-L-tyrosine + 2 NADPH R10060 S-adenosyl-L-methionine:glycine N-methyltransferase [N,N-dimethylglycine-forming]; 2 S-Adenosyl-L-methionine + Glycine <=> 2 S-Adenosyl-L-homocysteine + N,N-Dimethylglycine R10061 S-adenosyl-L-methionine:sarcosine N-methyltransferase [betaine-forming]; 2 S-Adenosyl-L-methionine + Sarcosine <=> 2 S-Adenosyl-L-homocysteine + Betaine R10062 S-adenosyl-L-methionine:glycine N-methyltransferase [betaine-forming]; 3 S-Adenosyl-L-methionine + Glycine <=> 3 S-Adenosyl-L-homocysteine + Betaine R10063 UDP-glucose:delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside 3',5'-O-glucosyltransferase; 2 UDP-glucose + Delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside <=> 2 UDP + Ternatin C5 R10065 ATP:1D-myo-inositol-1,4,5-trisphosphate 3,6-phosphotransferase; 2 ATP + D-myo-Inositol 1,4,5-trisphosphate <=> 2 ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate R10066 ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); ent-Kaurene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Kaur-16-en-18-oic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R10067 ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Kaur-16-en-18-oic acid + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Gibberellin A12 + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R10068 magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating); Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 Oxygen <=> Divinylprotochlorophyllide + 3 NADP+ + 5 H2O R10069 flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3',5'-dihydroxylating); Flavanone + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 3',5'-Dihydroxyflavanone + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10070 zeaxanthin,NADH:oxygen oxidoreductase; Zeaxanthin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Violaxanthin + 4 Oxidized ferredoxin + 2 H2O R10072 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5-hydroxylating); (+)-epi-Isozizaene + 4 Reduced [2Fe-2S] ferredoxin + 4 H+ + 2 Oxygen <=> Albaflavenone + 4 Oxidized [2Fe-2S] ferredoxin + 3 H2O R10073 (-)-vetispiradiene,[reduced NADPH---hemoprotein reductase]:oxygen 2alpha-oxidoreductase; Vetispiradiene + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Solavetivone + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R10074 glutaryl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; Glutaryl-CoA + Electron-transferring flavoprotein <=> Glutaconyl-1-CoA + Reduced electron-transferring flavoprotein R10075 (11R)-dihydroartemisinic-aldehyde:NADP+ Delta11(13)-oxidoreductase; (11R)-Dihydroartemisinic aldehyde + NADP+ <=> Artemisinic aldehyde + NADPH + H+ R10076 1,8-cineole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating); 1,8-Cineole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-exo-Hydroxy-1,8-cineole + [Oxidized NADPH---hemoprotein reductase] + H2O R10077 Abietinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abieta-7,13-dien-18,18-diol + [Oxidized NADPH---hemoprotein reductase] + H2O R10078 Abieta-7,13-dien-18,18-diol <=> Abietal + H2O R10079 carbamate hydro-lyase; cyanate hydratase; Cyanate + HCO3- + H+ <=> Ammonia + 2 CO2 R10080 chlorophyllide-a oxygenase; Chlorophyllide + 2 Oxygen + 2 NADPH + 2 H+ <=> Chlorophyllide b + 3 H2O + 2 NADP+ R10081 L-arginine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating); 2-Oxoglutarate + L-Arginine + Oxygen <=> Succinate + CO2 + 5-Hydroxy-L-arginine R10082 5-Hydroxy-L-arginine <=> Guanidine + L-Glutamate 5-semialdehyde R10086 L-glutamate:ferredoxin oxidoreductase (deaminating); L-Glutamate + 2 Oxidized ferredoxin + H2O <=> Ammonia + 2-Oxoglutarate + 2 Reduced ferredoxin + 2 H+ R10088 D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase; D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + Ammonia <=> Pyridoxal phosphate + 4 H2O + Orthophosphate R10089 D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase (glutamine-hydrolyzing); D-Ribose 5-phosphate + D-Glyceraldehyde 3-phosphate + L-Glutamine <=> Pyridoxal phosphate + L-Glutamate + 3 H2O + Orthophosphate R10090 citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (AMP-forming); Citrate + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + AMP + Diphosphate R10091 N2-citryl-N6-acetyl-N6-hydroxy-L-lysine:N6-acetyl-N6-hydroxy-L-lysine ligase (AMP-forming); N2-Citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-Acetyl-N6-hydroxy-L-lysine + ATP <=> Aerobactin + AMP + Diphosphate R10092 carbonate hydro-lyase (carbon-dioxide-forming); HCO3- + H+ <=> CO2 + H2O R10093 ATP:isopentenyl phosphate phosphotransferase; ATP + Isopentenyl phosphate <=> ADP + Isopentenyl diphosphate R10094 2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase; 2'-Deamino-2'-hydroxyneamine + 2-Oxoglutarate <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + L-Glutamate R10095 trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate:diphosphate phospho-alpha-D-ribosyltransferase; Decaprenol phosphate + 5-Phospho-alpha-D-ribose 1-diphosphate <=> trans,octacis-Decaprenylphospho-beta-D-ribofuranose 5-phosphate + Diphosphate R10096 UDP-alpha-D-glucose:2-deoxystreptamine 4-O-alpha-D-glucosyltransferase; UDP-glucose + 2-Deoxystreptamine <=> UDP + 2'-Deamino-2'-hydroxyparomamine R10097 2,4-Dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + Hydrochloric acid R10098 3-O-alpha-D-glucopyranosyl-L-rhamnopyranose:phosphate beta-D-glucosyltransferase; 3-O-alpha-D-Glucopyranosyl-L-rhamnopyranose + Orthophosphate <=> L-Rhamnose + beta-D-Glucose 1-phosphate R10099 acetyl-CoA:UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase; acetyl-CoA:UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose 4-N-acetyltransferase; UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + Acetyl-CoA <=> UDP-N,N'-diacetylbacillosamine + CoA R10100 acetyl-CoA:UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate 3-N-acetyltransferase; Acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate <=> CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate R10101 4-methylaminobutanoate methylamidohydrolase; 4-methylaminobutanoate:oxygen oxidoreductase (methylamine-forming); 4-Methylaminobutyrate + Oxygen + H2O <=> Succinate semialdehyde + Methylamine + Hydrogen peroxide R10102 4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming); 4-methylaminobutanoate:oxygen oxidoreductase (demethylating); 4-Methylaminobutyrate + Oxygen + H2O <=> 4-Aminobutanoate + Formaldehyde + Hydrogen peroxide R10103 4-(methylamino)-1-(pyridin-3-yl)butan-1-one:c-type cytochrome oxidoreductase (methylamine releasing); Pseudooxynicotine + H2O + 2 Ferricytochrome c <=> 4-Oxo-1-(3-pyridyl)-1-butanone + Methylamine + 2 Ferrocytochrome c + 2 H+ R10104 long-chain acyl-CoA:NADPH reductase; Long-chain acyl-CoA + 2 NADPH + 2 H+ <=> Long-chain alcohol + 2 NADP+ + CoA R10105 4-oxo-4-(pyridin-3-yl)butanal:NADP+ oxidoreductase; 4-Oxo-1-(3-pyridyl)-1-butanone + NADP+ + H2O <=> 3-Succinoylpyridine + NADPH + H+ R10106 L-arginine,NADH:oxygen oxidoreductase (nitric-oxide-forming); 2 L-Arginine + 3 NADH + 3 H+ + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 NAD+ + 4 H2O R10107 L-Arginine + Oxygen + NADH + H+ <=> N(omega)-Hydroxyarginine + NAD+ + H2O R10108 2 N(omega)-Hydroxyarginine + NADH + H+ + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + NAD+ + 2 H2O R10109 5-nitrosalicylate:oxygen 1,2-oxidoreductase (recyclizing); 5-Nitrosalicylate + Oxygen <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite R10110 5-nitrosalicylate:oxygen 1,2-oxidoreductase (decyclizing); 5-Nitrosalicylate + Oxygen <=> 4-Nitro-6-oxohepta-2,4-dienedioate R10111 4-Nitro-6-oxohepta-2,4-dienedioate <=> 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + Nitrite R10112 trans,octacis-decaprenylphospho-beta-D-ribofuranose:FAD 2-oxidoreductase; trans,octacis-Decaprenylphospho-beta-D-ribofuranose + FAD <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2 R10113 trans,octacis-decaprenylphospho-beta-D-arabinofuranose:NAD+ 2-oxidoreductase; trans,octacis-Decaprenylphospho-beta-D-arabinofuranose + NAD+ <=> trans,octacis-Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H+ R10114 ecgonine methyl ester:NADP+ oxidoreductase; Ecgonine methyl ester + NADP+ <=> Ecgonone methyl ester + NADPH + H+ R10115 malonyl-[acyl-carrier protein]-methyl-ester:malonyl-[acyl-carrier protein] C-acyltransferase; Malonyl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketoglutaryl-[acp] methyl ester + CO2 + Acyl-carrier protein R10116 3-hydroxyglutaryl-[acp]-methyl-ester:NADP+ oxidoreductase; 3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+ R10117 3-hydroxyglutaryl-[acp]-methyl-ester hydro-lyase; 3-Hydroxyglutaryl-[acp] methyl ester <=> Enoylglutaryl-[acp] methyl ester + H2O R10118 glutaryl-[acp]-methyl-ester:NADP+ oxidoreductase; Enoylglutaryl-[acp] methyl ester + NADPH + H+ <=> Glutaryl-[acp] methyl ester + NADP+ R10119 glutaryl-[acp]-methyl-ester:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating); Glutaryl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketopimeloyl-[acp] methyl ester + CO2 + Acyl-carrier protein R10120 3-hydroxypimeloyl-[acp]-methyl-ester:NADP+ oxidoreductase; 3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+ R10121 3-hydroxypimeloyl-[acp]-methyl-ester hydro-lyase; 3-Hydroxypimeloyl-[acp] methyl ester <=> Enoylpimeloyl-[acp] methyl ester + H2O R10122 pimelyl-[acyl-carrier protein]-methyl-ester:NADP+ oxidoreductase; Enoylpimeloyl-[acp] methyl ester + NADPH + H+ <=> Pimeloyl-[acyl-carrier protein] methyl ester + NADP+ R10123 acyl-[acyl-carrier protein],reduced-flavodoxin:oxygen oxidoreductase (pimeloyl-[acyl-carrier protein] forming); Long-chain acyl-[acyl-carrier protein] + 2 Reduced flavodoxin + 3 Oxygen <=> Pimeloyl-[acyl-carrier protein] + n-Alkanal + 2 Oxidized flavodoxin + 3 H2O R10124 pimeloyl-[acyl-carrier protein]:L-alanine C-pimeloyltransferase (decarboxylating); Pimeloyl-[acyl-carrier protein] + L-Alanine <=> 8-Amino-7-oxononanoate + Acyl-carrier protein + CO2 R10125 beta-Citronellol + NAD+ <=> (R)-(+)-Citronellal + NADH + H+ R10126 (-)-Citronellol + NAD+ <=> (S)-(-)-Citronellal + NADH + H+ R10127 biotin:NADP+ S-oxidoreductase (biotin S-oxide-forming); Biotin sulfoxide + NADPH + H+ <=> Biotin + NADP+ + H2O R10128 chanoclavine-I:NAD+ oxidoreductase; Chanoclavine-I + NAD+ <=> Chanoclavine-I aldehyde + NADH + H+ R10129 (-)-secoisolariciresinol:NAD+ oxidoreductase; Secoisolariciresinol + 2 NAD+ <=> Matairesinol + 2 NADH + 2 H+ R10130 2-deoxy-scyllo-inosamine:NADP+ 1-oxidoreductase; 2-Deoxy-scyllo-inosamine + NADP+ <=> 3-Amino-2,3-dideoxy-scyllo-inosose + NADPH + H+ R10131 3,3'-bipyridine-2,2',5,5',6,6'-hexol:NAD+ 11-oxidoreductase; 3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NAD+ <=> Blue pigment + NADH + H+ R10132 3,3'-bipyridine-2,2',5,5',6,6'-hexol:NADP+ 11-oxidoreductase; 3,3'-Bipyridine-2,2',5,5',6,6'-hexol + NADP+ <=> Blue pigment + NADPH + H+ R10133 2-nitroimidazole nitrohydrolase; Azomycin + H2O <=> Imidazol-2-one + Nitrite R10134 mycophenolic acid O-acyl-glucuronide-ester hydrolase; Mycophenolic acid O-acyl-glucuronide + H2O <=> Mycophenolate + D-Glucuronate R10135 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonohydrolase; 2-Oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> Maleylpyruvate R10136 vanillate:tetrahydrofolate O-methyltransferase; Vanillate + Tetrahydrofolate <=> 3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate R10137 UDP-N-acetyl-alpha-D-glucosamine:trans,octacis-decaprenyl-phosphate N-acetylglucosaminephosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + Decaprenol phosphate <=> UMP + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol R10138 G00164 + UDP-D-glucuronate <=> G00165 + UDP R10139 G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP R10140 UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate:NAD+ 3-oxidoreductase; UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NAD+ <=> UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+ R10141 UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate:2-oxoglutarate aminotransferase; UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-Glutamate <=> UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-Oxoglutarate R10142 acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-galactose N-acetyltransferase; Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-galactose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose R10143 pentalenolactone-D,2-oxoglutarate:oxygen oxidoreductase; Pentalenolactone D + 2-Oxoglutarate + Oxygen <=> Pentalenolactone E + Succinate + CO2 + H2O R10144 pentalenolactone-E,2-oxoglutarate:oxygen oxidoreductase; Pentalenolactone E + 2-Oxoglutarate + Oxygen <=> Pentalenolactone F + Succinate + CO2 R10145 pentalenolactone-D,2-oxoglutarate:oxygen oxidoreductase; Pentalenolactone D + 2 2-Oxoglutarate + 2 Oxygen <=> Pentalenolactone F + 2 Succinate + 2 CO2 + H2O R10146 Sulfite + 3 NADH + 3 H+ <=> Hydrogen sulfide + 3 NAD+ + 3 H2O R10147 L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate-forming]; L-Aspartate 4-semialdehyde + Pyruvate <=> (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O R10149 Thiosulfate + Menaquinol <=> Sulfite + Hydrogen sulfide + Menaquinone R10150 Tetrathionate + 2 e- <=> 2 Thiosulfate R10151 Thiosulfate + 5 H2O + 8 Ferricytochrome c <=> 2 Sulfate + 8 Ferrocytochrome c + 10 H+ R10152 sulfide:quinone oxidoreductase; n Hydrogen sulfide + n Quinone <=> Polysulfide + n Hydroquinone R10153 L-glutamate 2,3-aminomutase; L-Glutamate <=> 3-Aminopentanedioate R10154 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (pentalenolactone-D forming); 1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Pentalenolactone D + NADP+ + H2O R10155 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (neopentalenolactone-D forming); 1-Deoxy-11-oxopentalenate + NADPH + H+ + Oxygen <=> Neopentalenolactone D + NADP+ + H2O R10156 1-deoxy-11beta-hydroxypentalenate:NAD+ oxidoreductase; 1-Deoxy-11beta-hydroxypentalenate + NAD+ <=> 1-Deoxy-11-oxopentalenate + NADH + H+ R10157 1-deoxypentalenic acid,2-oxoglutarate:oxygen oxidoreductase; 1-Deoxypentalenate + 2-Oxoglutarate + Oxygen <=> 1-Deoxy-11beta-hydroxypentalenate + Succinate + CO2 R10158 1-deoxypentalenate,reduced ferredoxin:oxygen oxidoreductase; 1-Deoxypentalenate + Reduced ferredoxin + Oxygen <=> Pentalenate + Oxidized ferredoxin + H2O R10159 adrenodoxin:NADP+ oxidoreductase; 2 Reduced adrenal ferredoxin + NADP+ + H+ <=> 2 Oxidized adrenal ferredoxin + NADPH R10160 cannabigerolate:oxygen oxidoreductase (cyclizing, cannabidiolate-forming); Cannabigerolate + Oxygen <=> Cannabidiolic acid + Hydrogen peroxide R10161 propanoyl-CoA:NAD+ oxidoreductase; Propanoyl-CoA + NAD+ <=> Propenoyl-CoA + NADH + H+ R10162 pentalenolactone-reduced-ferredoxin:oxygen oxidoreductase (pentalenolactone forming); Pentalenolactone F + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Pentalenolactone + 2 Oxidized ferredoxin + 2 H2O R10163 festuclavine:NAD+ oxidoreductase; Festuclavine + NAD+ <=> 6,8-Dimethyl-6,7-didehydroergoline + NADH + H+ R10164 hydroxylamine:ferricytochrome-c oxidoreductase; Hydroxylamine + H2O + 4 Ferricytochrome c <=> Nitrite + 4 Ferrocytochrome c + 5 H+ R10165 hydroxylamine:ferricytochrome-c oxidoreductase (nitric acid-forming); Hydroxylamine + 3 Ferricytochrome c <=> Nitric oxide + 3 Ferrocytochrome c + 3 H+ R10166 S-adenosyl-L-methionine:4-(3-methylbut-2-enyl)-L-tryptophan N-methyltransferase; 4-(3-Methylbut-2-enyl)-L-tryptophan + S-Adenosyl-L-methionine <=> 4-Dimethylallyl-L-abrine + S-Adenosyl-L-homocysteine R10167 S-adenosyl-L-methionine:squalene C-methyltransferase; S-Adenosyl-L-methionine + Squalene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene R10168 S-adenosyl-L-methionine:3-methyl-1,2-didehydro-2,3-dihydrosqualene C-methyltransferase; S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene <=> S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene R10169 S-adenosyl-L-methionine:squalene C-methyltransferase; 2 S-Adenosyl-L-methionine + Squalene <=> 2 S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene R10170 (2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming); (2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate R10171 malonyl-CoA:hexanoyl-CoA malonyltransferase (3,5,7-trioxododecanoyl-CoA-forming); 3 Malonyl-CoA + Hexanoyl-CoA <=> 3 CoA + 3,5,7-Trioxododecanoyl-CoA + 3 CO2 R10172 octanoyl-CoA:malonyl-[acyl-carrier protein] C-heptanoyltransferase (decarboxylating, CoA-forming); Octanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CoA + CO2 R10173 malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase; Malonyl-CoA + 2-Hydroxybenzoyl-CoA <=> 2 CoA + 4-Hydroxycoumarin + CO2 R10174 acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase; Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-D-glucose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-D-glucose R10175 dTDP-6-deoxy-beta-L-mannose:N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol 3-alpha-L-rhamnosyltransferase; dTDP-L-rhamnose + N-Acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP + alpha-L-Rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol R10176 geranyl-diphosphate:olivetolate geranyltransferase; Geranyl diphosphate + 2,4-Dihydroxy-6-pentylbenzoate <=> Diphosphate + Cannabigerolate R10177 geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene forming); 2 Geranylgeranyl diphosphate <=> 15-cis-Phytoene + 2 Diphosphate R10178 4-aminobutanoate:pyruvate aminotransferase; 4-Aminobutanoate + Pyruvate <=> Succinate semialdehyde + L-Alanine R10179 4-aminobutanoate:glyoxylate aminotransferase; 4-Aminobutanoate + Glyoxylate <=> Succinate semialdehyde + Glycine R10180 L-tryptophan:pyruvate aminotransferase; L-Tryptophan + Pyruvate <=> Indolepyruvate + L-Alanine R10181 indole-3-pyruvate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); Indolepyruvate + NADPH + H+ + Oxygen <=> Indole-3-acetate + NADP+ + H2O + CO2 R10182 CTP:N,N'-diacetyllegionaminate cytidylyltransferase; CTP + N,N'-Diacetyllegionaminate <=> CMP-N,N'-diacetyllegionaminate + Diphosphate R10183 UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase; UTP + N-Acetyl-alpha-D-galactosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-D-galactosamine R10184 UDP-N,N'-diacetylbacillosamine:tritrans,heptacis-undecaprenyl-phosphate N,N'-diacetylbacillosamine transferase; UDP-N,N'-diacetylbacillosamine + tritrans,heptacis-Undecaprenyl phosphate <=> UMP + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol R10185 ATP:methylphosphonate 5-triphosphoribosyltransferase; ATP + Methylphosphonate <=> alpha-D-Ribose 1-methylphosphonate 5-triphosphate + Adenine R10186 alpha-D-ribose-1-methylphosphonate-5-triphosphate diphosphohydrolase; alpha-D-Ribose 1-methylphosphonate 5-triphosphate + H2O <=> alpha-D-Ribose 1-methylphosphonate 5-phosphate + Diphosphate R10187 UDP-N,N'-diacetylbacillosamine hydrolase (2-epimerising); UDP-N,N'-diacetylbacillosamine + H2O <=> UDP + 2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose R10188 UDP-N-acetyl-alpha-D-galactosamine:N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol 3-alpha-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine + N,N'-Diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol <=> UDP + N-Acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyldiphospho-tritrans,heptacis-undecaprenol R10189 (2S)-2-hydroxycarboxylate:NAD+ oxidoreductase; (S)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+ R10190 dTDP-6-deoxy-beta-L-talose:NAD+ 4-oxidoreductase; dTDP-6-deoxy-beta-L-talose + NAD+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADH + H+ R10191 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (methylphosphonate forming); 2-Hydroxyethylphosphonate + Oxygen <=> Methylphosphonate + HCO3- R10192 zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing); Zeaxanthin + Oxygen <=> (3R)-11-cis-3-Hydroxyretinal + (3R)-all-trans-3-Hydroxyretinal R10193 (+)-larreatricin:oxygen 3'-hydroxylase; (+)-Larreatricin + Oxygen + Reduced acceptor <=> (+)-3'-Hydroxylarreatricin + Acceptor + H2O R10194 C30 botryococcene:NADP+ oxidoreductase; C30 Botryococcene + NADP+ + Diphosphate <=> Presqualene diphosphate + NADPH + H+ R10195 S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene R10196 S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene R10197 S-Adenosyl-L-methionine + C30 Botryococcene <=> S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene R10198 S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene <=> S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene R10199 S-adenosyl-L-methionine:botryococcene C-methyltransferase; 2 S-Adenosyl-L-methionine + C30 Botryococcene <=> 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene R10200 acetyl-CoA:fumigaclavine B O-acetyltransferase; Acetyl-CoA + Fumigaclavine B <=> CoA + Fumigaclavine A R10201 dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase; Fumigaclavine A + Dimethylallyl diphosphate <=> Fumigaclavine C + Diphosphate R10203 Dimethyl sulfone + 2 Reduced FMN + 2 Oxygen <=> Methanesulfonic acid + Formaldehyde + 2 FMN + 2 H2O R10204 alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming); alpha-D-Ribose 1-methylphosphonate 5-phosphate + S-Adenosyl-L-methionine + Reduced acceptor <=> alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + Methane + L-Methionine + 5'-Deoxyadenosine + Acceptor R10205 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 2-phosphohydrolase (alpha-D-ribose 1,5-bisphosphate-forming); alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 1,5-bisphosphate R10206 methanesulfonate,FMNH2:oxygen oxidoreductase; Methanesulfonic acid + Reduced FMN + Oxygen <=> FMN + Sulfite + H2O + Formaldehyde R10207 2'-deamino-2'-hydroxyparomamine:oxygen 6'-oxidoreductase; 2'-Deamino-2'-hydroxyparomamine + Oxygen <=> 2'-Deamino-2'-hydroxy-6'-dehydroparomamine + Hydrogen peroxide R10208 (3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (trans-2-enoyl-[acyl-carrier protein]-forming); (3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O R10209 tRNA-guanosine34:7-aminomethyl-7-carbaguanine tRNA-D-ribosyltransferase; tRNA guanine + 7-Aminomethyl-7-carbaguanine <=> tRNA 7-aminomethyl-7-carbaguanine + Guanine R10210 2-Oxoglutaryl-CoA + H2O <=> 2-Oxoglutarate + CoA R10211 S-(5-Hydroxy-2-furoyl)-CoA + H2O <=> 2-Oxoglutaryl-CoA R10212 Furfural + H2O + Oxygen <=> 2-Furoate + Hydrogen peroxide R10213 2,5-Furandicarboxylate <=> 2-Furoate + CO2 R10216 5-Hydroxymethyl-2-furaldehyde + H2O + Oxygen <=> 5-Hydroxymethyl-2-furoate + Hydrogen peroxide R10217 Furfural + NADH + H+ <=> Furfuryl alcohol + NAD+ R10218 5-Hydroxymethyl-2-furaldehyde + NADH + H+ <=> 5-Hydroxymethylfurfuryl alcohol + NAD+ R10219 Acetyl-CoA + Tetrahydrosarcinapterin <=> CoA + 5-Methyl-H4SPT + CO R10220 S-adenosyl-L-methionine:7-aminomethyl-7-deazaguanosine ribosyltransferase (ribosyl isomerizing; L-methionine, adenine releasing); S-Adenosyl-L-methionine + tRNA 7-aminomethyl-7-carbaguanine <=> L-Methionine + Adenine + Epoxyqueuosine in tRNA R10221 6-phospho-D-gluconate:NAD+ 2-oxidoreductase (decarboxylating); 6-Phospho-D-gluconate + NAD+ <=> D-Ribulose 5-phosphate + CO2 + NADH + H+ R10222 (R)-2-hydroxycarboxylate:NAD+ oxidoreductase; (R)-2-Hydroxyacid + NAD+ <=> 2-Oxo acid + NADH + H+ R10223 tRNA(adenine34) aminohydrolase; tRNA adenine + H2O <=> tRNA hypoxanthine + Ammonia R10224 norsolorinic acid anthrone:oxygen 9-oxidoreductase (norsolorinic acid-forming); Norsolorinic acid anthrone + Oxygen <=> Norsolorinic acid + H2O R10225 (+)-lariciresinol:NADP+ oxidoreductase; Lariciresinol + NADP+ <=> (+)-Pinoresinol + NADPH + H+ R10226 (-)-secoisolariciresinol:NADP+ oxidoreductase; Secoisolariciresinol + NADP+ <=> Lariciresinol + NADPH + H+ R10227 (-)-lariciresinol:NADP+ oxidoreductase; (-)-Lariciresinol + NADP+ <=> (-)-Pinoresinol + NADPH + H+ R10228 (+)-secoisolariciresinol:NADPH+ oxidoreductase; (+)-Secoisolariciresinol + NADP+ <=> (-)-Lariciresinol + NADPH + H+ R10229 agroclavine:NADP+ oxidoreductase; Agroclavine + NADP+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+ R10230 hydroxylamine:oxygen oxidoreductase; Hydroxylamine + Oxygen <=> Nitrite + H2O + H+ R10231 tRNA(Ala)-adenine37 aminohydrolase; tRNA(Ala) adenine + H2O <=> tRNA(Ala) hypoxanthine + Ammonia R10232 tRNA(cytosine8) aminohydrolase; tRNA cytosine + H2O <=> tRNA uridine + Ammonia R10233 4-coumaroyl-CoA:malonyl-CoA 4-coumaryltransferase (bisdemethoxycurcumin-forming); 2 p-Coumaroyl-CoA + Malonyl-CoA + H2O <=> 3 CoA + Bisdemethoxycurcumin + 2 CO2 R10234 4-coumaroyl-CoA:malonyl-CoA 4-coumaryltransferase (4-hydroxybenzalacetone-forming); p-Coumaroyl-CoA + Malonyl-CoA + H2O <=> 2 CoA + 4-Hydroxycinnamoylmethane + 2 CO2 R10235 deoxyinosine diphosphate phosphatase; dIDP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Orthophosphate R10236 1-O-(4-hydroxycinnamoyl)-beta-D-glucose:cyanidin 3-O-(6-O-beta-D-glucosyl-2-O-beta-D-xylosyl-beta-D-galactoside) 6'''-O-(4-hydroxycinnamoyl)transferase; p-Coumaroyl-D-glucose + Cyanidin 3-O-(6''-glucosyl-2''-xylosylgalactoside) <=> beta-D-Glucose + Cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] R10237 4-hydroxycinnamoyl-CoA:anthocyanin-3-O-glucoside 6''-O-acyltransferase; p-Coumaroyl-CoA + Anthocyanidin 3-O-beta-D-glucoside <=> CoA + Anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] R10238 malonyl-CoA:malonyl-CoA malonyltransferase (5,7-dihydroxy-2-methyl-4H-chromen-4-one-forming); 5 Malonyl-CoA <=> 5 CoA + 5,7-Dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O R10239 malonyl-CoA:hexanoate malonyltransferase (norsolorinic acid anthrone-forming); 7 Malonyl-CoA + Hexanoyl-[acp] <=> 7 CoA + Norsolorinic acid anthrone + Acyl-carrier protein + 7 CO2 + 2 H2O R10240 UDP-alpha-D-galactose:cyanidin 3-O-galactosyltransferase; UDP-alpha-D-galactose + Cyanidin <=> UDP + Cyanidin 3-O-galactoside R10241 (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (sclareol forming); copal-8-ol-diphosphate diphosphate-lyase (sclareol-forming); Copal-8-ol diphosphate + H2O <=> Sclareol + Diphosphate R10242 5alpha-androstane-3,17-dione:NADP+ delta4-oxidoreductase; 5alpha-Androstane-3,17-dione + NADP+ <=> Androstenedione + NADPH + H+ R10243 Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO R10244 purine-deoxynucleoside:phosphate ribosyltransferase; Purine deoxyribonucleoside + Orthophosphate <=> Purine + 2-Deoxy-D-ribose 1-phosphate R10245 Iminoglycine + H2O <=> Glyoxylate + Ammonia R10246 L-tyrosine 4-methylphenol-lyase (2-iminoacetate-forming); L-Tyrosine + S-Adenosyl-L-methionine + Reduced acceptor <=> Iminoglycine + 4-Cresol + 5'-Deoxyadenosine + L-Methionine + Acceptor R10247 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase; 1-Deoxy-D-xylulose 5-phosphate + Iminoglycine + Thiocarboxy-[sulfur-carrier protein] <=> 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + Sulfur-carrier protein + 2 H2O R10248 eugenol:NADP+ oxidoreductase (coniferyl ester reducing); Coniferyl acetate + NADPH + H+ <=> Eugenol + NADP+ + Acetate R10249 chavicol:NADP+ oxidoreductase; Coumaryl acetate + NADPH + H+ <=> Chavicol + NADP+ + Acetate R10250 S-adenosyl-L-methionine:eugenol O-methyltransferase; Eugenol + S-Adenosyl-L-methionine <=> Methyleugenol + S-Adenosyl-L-homocysteine R10251 S-adenosyl-L-methionine:chavicol O-methyltransferase; Chavicol + S-Adenosyl-L-methionine <=> Estragole + S-Adenosyl-L-homocysteine R10252 S-adenosyl-L-methionine:trans-anol O-methyltransferase; Isochavicol + S-Adenosyl-L-methionine <=> Anethole + S-Adenosyl-L-homocysteine R10253 Coniferyl alcohol + Acetyl-CoA <=> Coniferyl acetate + CoA R10254 4-Coumaryl alcohol + Acetyl-CoA <=> Coumaryl acetate + CoA R10255 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol:L-serine 2,3-bis-(O-geranylgeranyl)-sn-glycerol phosphotransferase; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine R10256 UDP-alpha-D-xylose:anthocyanidin-3-O-beta-D-glucoside 2'''-O-xylosyltransferase; UDP-D-xylose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-beta-D-sambubioside R10257 UDP-alpha-D-xylose:cyanidin-3-O-beta-D-galactoside 2''-O-xylosyltransferase; UDP-D-xylose + Cyanidin 3-O-galactoside <=> UDP + Cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-galactoside) R10258 quercetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Quercetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Myricetin + [Oxidized NADPH---hemoprotein reductase] + H2O R10259 1-O-vanilloyl-beta-D-glucose:cyanidin-3-O-beta-D-glucoside 7-O-beta-D-glucosyltransferase; 1-O-Vanilloyl-beta-D-glucose + Cyanidin 3-O-glucoside <=> Vanillate + Cyanidin 3,7-di-O-beta-D-glucoside R10260 luteolin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Luteolin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Tricetin + [Oxidized NADPH---hemoprotein reductase] + H2O R10261 1-O-sinapoyl-beta-D-glucose:cyanidin-3-O-beta-D-glucoside 5-O-beta-D-glucosyltransferase; 1-O-Sinapoyl-beta-D-glucose + Cyanidin 3-O-glucoside <=> Sinapate + Cyanidin 3,5-O-diglucoside R10262 UDP-alpha-D-glucose:anthocyanidin-3-O-beta-D-glucoside 5-O-glucosyltransferase; UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin-3,5-diglucoside R10263 UDP-alpha-D-glucose:anthocyanidin-3-O-glucoside 2''-O-glucosyltransferase; UDP-glucose + Anthocyanidin 3-O-beta-D-glucoside <=> UDP + Anthocyanidin 3-O-sophoroside R10264 UDP-alpha-D-glucose:anthocyanidin-3-O-[3-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucosyltransferase; UDP-glucose + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] <=> UDP + Anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside R10265 UDP-alpha-D-glucose:anthocyanidin-3-O-beta-D-sambubioside 5-O-glucosyltransferase; UDP-glucose + Anthocyanidin 3-O-beta-D-sambubioside <=> UDP + Anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside R10266 UDP-N-acetyl-alpha-D-glucosamine hydro-lyase; UDP-N-acetyl-alpha-D-glucosamine <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + H2O R10267 (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing; NADH-forming); ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> AMP + Orthophosphate + NADH R10268 (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide-phosphate hydro-lyase (ADP-hydrolysing; NADPH-forming); ADP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> AMP + Orthophosphate + NADPH R10269 Sporulenol <=> Tetraprenyl-beta-curcumene + H2O R10270 (5R)-5-phosphooxy-L-lysine phosphate-lyase (deaminating; (S)-2-amino-6-oxohexanoate-forming); 5-Phosphooxy-L-lysine + H2O <=> L-2-Aminoadipate 6-semialdehyde + Ammonia + Orthophosphate R10271 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, Delta6-protoilludene-forming); trans,trans-Farnesyl diphosphate <=> Delta6-Protoilludene + Diphosphate R10272 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-alpha-isocomene-forming); trans,trans-Farnesyl diphosphate <=> (-)-alpha-Isocomene + Diphosphate R10273 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (E)-2-epi-beta-caryophyllene-forming); trans,trans-Farnesyl diphosphate <=> (E)-2-epi-beta-Caryophyllene + Diphosphate R10274 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-epi-alpha-bisabolol-forming); trans,trans-Farnesyl diphosphate + H2O <=> (+)-epi-alpha-Bisabolol + Diphosphate R10275 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming); trans,trans-Farnesyl diphosphate <=> Valerena-4,7(11)-diene + Diphosphate R10276 (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (cis-abienol forming); copal-8-ol-diphosphate diphosphate-lyase (cis-abienol forming); Copal-8-ol diphosphate <=> cis-Abienol + Diphosphate R10277 L-lysine ammonia-lyase (cyclizing; ammonia-forming); L-Lysine <=> L-Pipecolate + Ammonia R10278 3,5,7-trioxododecanoyl-CoA CoA-lyase (2,4-dihydroxy-6-pentylbenzoate-forming); 3,5,7-Trioxododecanoyl-CoA <=> CoA + 2,4-Dihydroxy-6-pentylbenzoate R10279 dTDP-6-deoxy-beta-L-talose 4-epimerase; dTDP-6-deoxy-beta-L-talose <=> dTDP-L-rhamnose R10280 (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide 6-epimerase; (6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide R10281 (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide-phosphate 6-epimerase; (6R)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate R10282 beta-carotene 9-cis-all-trans isomerase; beta-Carotene <=> 9-cis-beta-Carotene R10283 (4S)-4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming); (4S)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate R10284 (2Z,6Z)-farnesyl-diphosphate diphosphate-lyase (cyclizing; 7-epizingiberene-forming); 2-cis,6-cis-Farnesyl diphosphate <=> 7-Epizingiberene + Diphosphate R10285 choline trimethylamine-lyase (acetaldehyde-forming); Choline <=> Trimethylamine + Acetaldehyde + H+ R10286 L-phenylalanine 2,3-aminomutase [(R)-3-amino-3-phenylpropanoate forming]; L-Phenylalanine <=> L-beta-Phenylalanine R10287 L-phenylalanine 2,3-aminomutase [(S)-3-amino-3-phenylpropanoate]; L-Phenylalanine <=> D-beta-Phenylalanine R10288 (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide-phosphate hydro-lyase (ATP-hydrolysing; NADPH-forming); ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate <=> ADP + Orthophosphate + NADPH R10289 isochavicol:NADP+ oxidoreductase; Coumaryl acetate + NADPH + H+ <=> Isochavicol + Acetate + NADP+ R10290 UDP-alpha-D-xylose:pelargonidin-3-O-beta-D-glucoside 2'''-O-xylosyltransferase; Pelargonidin 3-O-glucoside + UDP-D-xylose <=> Pelargonidin 3-O-beta-D-sambubioside + UDP R10291 UDP-alpha-D-xylose:cyanidin-3-O-beta-D-glucoside 2'''-O-xylosyltransferase; Cyanidin 3-O-glucoside + UDP-D-xylose <=> Cyanidin 3-O-beta-D-sambubioside + UDP R10292 UDP-alpha-D-xylose:delphinidin-3-O-beta-D-glucoside 2'''-O-xylosyltransferase; Delphinidin 3-O-glucoside + UDP-D-xylose <=> Delphinidin 3-O-beta-D-sambubioside + UDP R10293 UDP-alpha-D-glucose:pelargonidin-3-O-beta-D-sambubioside 5-O-glucosyltransferase; Pelargonidin 3-O-beta-D-sambubioside + UDP-glucose <=> Pelargonidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP R10294 UDP-alpha-D-glucose:cyanidin-3-O-beta-D-sambubioside 5-O-glucosyltransferase; Cyanidin 3-O-beta-D-sambubioside + UDP-glucose <=> Cyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP R10295 UDP-alpha-D-glucose:delphinidin-3-O-beta-D-sambubioside 5-O-glucosyltransferase; Delphinidin 3-O-beta-D-sambubioside + UDP-glucose <=> Delphinidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP R10296 1-O-vanilloyl-beta-D-glucose:pelargonidin-3-O-beta-D-glucoside 7-O-beta-D-glucosyltransferase; 1-O-Vanilloyl-beta-D-glucose + Pelargonidin 3-O-glucoside <=> Vanillate + Pelargonidin 3,7-di-O-beta-D-glucoside R10297 1-O-vanilloyl-beta-D-glucose:delphinidin-3-O-beta-D-glucoside 7-O-beta-D-glucosyltransferase; 1-O-Vanilloyl-beta-D-glucose + Delphinidin 3-O-glucoside <=> Vanillate + Delphinidin 3,7-di-O-beta-D-glucoside R10298 1-O-sinapoyl-beta-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-beta-D-glucosyltransferase; Pelargonidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Pelargonin + Sinapate R10299 1-O-sinapoyl-beta-D-glucose:delphinidin-3-O-beta-D-glucoside 5-O-beta-D-glucosyltransferase; Delphinidin 3-O-glucoside + 1-O-Sinapoyl-beta-D-glucose <=> Delphinidin 3,5-diglucoside + Sinapate R10301 S-(hydroxymethyl)mycothiol:NAD+ oxidoreductase; S-(Hydroxymethyl)mycothiol + NAD+ + H2O <=> Formate + Mycothiol + NADH + H+ R10302 Formaldehyde + Mycothiol <=> S-(Hydroxymethyl)mycothiol R10303 dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose:lipid II 4-acetamido-4,6-dideoxy-D-galactosyltransferase; N-Acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose <=> 4-Acetamido-4,6-dideoxy-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-mannosaminuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP R10304 phosphoenolpyruvate:2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose 1-(2-carboxy-2-oxoethyl)transferase; 2,4-Diacetamido-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> N,N'-Diacetyllegionaminate + Orthophosphate R10305 O3-acetyl-L-serine:L-homocysteine S-(2-amino-2-carboxyethyl)transferase; O-Acetyl-L-serine + L-Homocysteine <=> L-Cystathionine + Acetate R10306 S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine-[translation elongation factor 2] methyltransferase; 3 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 3 S-Adenosyl-L-homocysteine + Peptide diphthine R10307 S-adenosyl-L-methionine:dihydrosterigmatocystin 8-O-methyltransferase; S-Adenosyl-L-methionine + Dihydrosterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydro-O-methylsterigmatocystin R10308 geraniol:NAD+ oxidoreductase; Geraniol + NAD+ <=> Geranial + NADH + H+ R10309 (1'S)-averantin:NADP+ oxidoreductase; (1'S)-Averantin + NADP+ <=> Norsolorinic acid + NADPH + H+ R10310 (1'S,5'S)-hydroxyaverantin:NAD+ oxidoreductase; (1'S,5'S)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+ R10311 (1'S,5'R)-hydroxyaverantin:NAD+ oxidoreductase; (1'S,5'R)-5'-Hydroxyaverantin + NAD+ <=> 5'-Oxoaverantin + NADH + H+ R10312 kanamycin-B,2-oxoglutarate:oxygen oxidoreductase (deaminating, 2'-hydroxylating); Kanamycin B + 2-Oxoglutarate + Oxygen <=> 2'-Dehydrokanamycin A + Succinate + Ammonia + CO2 R10313 11-oxo-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating); 11-Oxo-beta-amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 30-Hydroxy-11-oxo-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O R10314 30-hydroxy-11-oxo-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating); 30-Hydroxy-11-oxo-beta-amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetaldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10315 glycyrrhetaldehyde,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating); Glycyrrhetaldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetinate + [Oxidized NADPH---hemoprotein reductase] + H2O R10316 11-oxo-beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating); 11-Oxo-beta-amyrin + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Glycyrrhetinate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R10317 (1'S)-averantin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating); (1'S)-Averantin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (1'S,5'S)-5'-Hydroxyaverantin + [Oxidized NADPH---hemoprotein reductase] + H2O R10318 (1'S)-averantin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating); (1'S)-Averantin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (1'S,5'R)-5'-Hydroxyaverantin + [Oxidized NADPH---hemoprotein reductase] + H2O R10319 8-O-methylsterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming); O-Methylsterigmatocystin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Aflatoxin B1 + 2 [Oxidized NADPH---hemoprotein reductase] + H2O + Methanol + CO2 R10320 8-O-methyldihydrosterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming); Dihydro-O-methylsterigmatocystin + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Aflatoxin B2 + 2 [Oxidized NADPH---hemoprotein reductase] + H2O + Methanol + CO2 R10321 tryprostatin B,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxytryprostatin B-forming); Tryprostatin B + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxytryprostatin B + [Oxidized NADPH---hemoprotein reductase] + H2O R10322 cyclo(L-leucyl-L-leucyl),reduced-ferredoxin:oxygen oxidoreductase (N-hydroxylating,aromatizing); Cyclo(L-leucyl-L-leucyl) + 6 Reduced ferredoxin + 3 Oxygen <=> Pulcherriminic acid + 6 Oxidized ferredoxin + 4 H2O R10323 cyclo(L-tyrosyl-L-tyrosyl),reduced ferredoxin:oxygen oxidoreductase (diarylbridge-forming); Cyclo(L-tyrosyl-L-tyrosyl) + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Mycocyclosin + 2 Oxidized ferredoxin + 2 H2O R10324 D-glyceraldehyde:acceptor oxidoreductase (FAD-containing); D-Glyceraldehyde + H2O + Acceptor <=> D-Glycerate + Reduced acceptor R10325 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NAD+ oxidoreductase; 2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NAD+ <=> 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate + 8 NADH + 8 H+ R10326 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NADP+ oxidoreductase; 2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NADP+ <=> 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate + 8 NADPH + 8 H+ R10327 cyclo(L-leucyl-L-phenylalanyl):oxygen oxidoreductase; Cyclo(L-leucyl-L-phenylalanyl) + Oxygen <=> Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Hydrogen peroxide R10328 cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl]:oxygen oxidoreductase; Cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + Oxygen <=> Albonoursin + Hydrogen peroxide R10329 cyclo(L-leucyl-L-phenylalanyl):oxygen oxidoreductase; Cyclo(L-leucyl-L-phenylalanyl) + 2 Oxygen <=> Albonoursin + 2 Hydrogen peroxide R10330 dihydrourocanate:acceptor oxidoreductase; Dihydrourocanate + Acceptor <=> Urocanate + Reduced acceptor R10331 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid:ferredoxin oxidoreductase; 2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate + Acceptor <=> 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate + Reduced acceptor R10332 5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase; 5,6,7,8-Tetrahydromethanopterin + NAD+ <=> 7,8-Dihydromethanopterin + NADH + H+ R10333 S,S-dimethyl-beta-propiothetin:tetrahydrofolate S-methyltransferase; S,S-Dimethyl-beta-propiothetin + Tetrahydrofolate <=> 3-(Methylthio)propanoate + 5-Methyltetrahydrofolate R10334 L-leucyl-tRNALeu:L-phenylalanyl-tRNAPhe leucyltransferase (cyclizing); L-Leucyl-tRNA + L-Phenylalanyl-tRNA(Phe) <=> tRNA(Leu) + tRNA(Phe) + Cyclo(L-leucyl-L-phenylalanyl) R10335 L-tyrosyl-tRNATyr:L-tyrosyl-tRNATyr tyrosyltransferase (cyclizing); 2 L-Tyrosyl-tRNA(Tyr) <=> 2 tRNA(Tyr) + Cyclo(L-tyrosyl-L-tyrosyl) R10336 L-leucyl-tRNALeu:L-leucyl-tRNALeu leucyltransferase (cyclizing); 2 L-Leucyl-tRNA <=> 2 tRNA(Leu) + Cyclo(L-leucyl-L-leucyl) R10337 5-phospho-alpha-D-ribose 1-diphosphate:4-aminobenzoate 5-phospho-beta-D-ribofuranosyltransferase (decarboxylating); 5-Phospho-alpha-D-ribose 1-diphosphate + 4-Aminobenzoate <=> 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate + CO2 + Diphosphate R10338 S-adenosyl-3-(methylsulfanyl)propylamine:agmatine 3-aminopropyltransferase; S-Adenosylmethioninamine + Agmatine <=> 5'-Methylthioadenosine + N1-(3-Aminopropyl)agmatine R10339 (7,8-dihydropterin-6-yl)methyl-diphosphate:4-(beta-D-ribofuranosyl)aniline-5'-phosphate 6-hydroxymethyl-7,8-dihydropterintransferase; 6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-(beta-D-Ribofuranosyl)aniline 5'-phosphate <=> N-[(7,8-Dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + Diphosphate R10340 dimethylallyl-diphosphate:brevianamide-F dimethylallyl-C-2-transferase; Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Tryprostatin B R10341 dimethylallyl-diphosphate:verruculogen dimethylallyl-O-transferase; Dimethylallyl diphosphate + Verruculogen <=> Diphosphate + Fumitremorgin A R10342 ATP:ATP adenylyltransferase (cyclizing); 2 ATP <=> 2 Diphosphate + Cyclic di-3',5'-adenylate R10343 succinyl-CoA:acetate CoA-transferase; Succinyl-CoA + Acetate <=> Acetyl-CoA + Succinate R10344 7,8-dihydroneopterin 2',3'-cyclic phosphate 3'-phosphodiesterase; 7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> Dihydroneopterin phosphate R10345 7,8-dihydroneopterin 2',3'-cyclic phosphate 2'-phosphodiesterase; 7,8-Dihydroneopterin 2',3'-cyclic phosphate + H2O <=> 7,8-Dihydroneopterin 2'-phosphate R10346 beta-L-arabinofuranoside non-reducing end beta-L-arabinofuranosidase; beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O <=> 2 beta-L-Arabinofuranose R10347 N1-aminopropylagmatine amidinohydrolase; N1-(3-Aminopropyl)agmatine + H2O <=> Spermidine + Urea R10348 GTP 7,8-8,9-dihydrolase (cyclizing, formate-releasing, diphosphate-releasing); GTP + H2O <=> 7,8-Dihydroneopterin 2',3'-cyclic phosphate + Formate + Diphosphate R10349 Geranylgeranyl diphosphate + Indoleglycerol phosphate <=> 3-Geranylgeranylindole + D-Glyceraldehyde 3-phosphate + Diphosphate R10350 3-geranylgeranylindole,NADPH:oxygen oxidoreductase (10,11-epoxidizing); 3-Geranylgeranylindole + Oxygen + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O R10351 emindole-SB,NADPH:oxygen oxidoreductase (14,15-epoxidizing); Emindole SB + Oxygen + NADPH + H+ <=> 14,15-Epoxyemindole SB + NADP+ + H2O R10352 10,11-Epoxy-3-geranylgeranylindole <=> Emindole SB R10353 14,15-Epoxyemindole SB <=> Paspaline R10356 paspaline-B,NADPH:oxygen oxidoreductase; Paspaline B + NADPH + H+ + Oxygen <=> 12-Demethyl-11,12-dehydropaspaline + NADP+ + H2O + Formate R10357 12-Demethyl-11,12-dehydropaspaline + Oxygen + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O R10358 beta-PC-M6 + Oxygen + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O R10359 13-desoxypaxilline,NADPH:oxygen oxidoreductase; 13-Desoxypaxilline + NADPH + H+ + Oxygen <=> Paxilline + NADP+ + H2O R10360 Paxilline + 2 Dimethylallyl diphosphate <=> 21,22-Diprenylpaxilline + 2 Diphosphate R10361 13-Desoxypaxilline + NADPH + Oxygen + H+ <=> Paspalicine + NADP+ + 2 H2O R10362 Paspalicine + Oxygen + NADPH + H+ <=> Paspalinine + NADP+ + H2O R10365 dimethylallyl-diphosphate:paspalinine dimethylallyltransferase; Paspalinine + Dimethylallyl diphosphate <=> Aflatrem + Diphosphate R10366 13-desoxyterpendole I,NADPH:oxygen oxidoreductase; 13-Desoxyterpendole I + NADPH + H+ + Oxygen <=> Terpendole I + NADP+ + H2O R10367 20,21-Diprenylterpendole I + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O R10368 Lolitrem E + NADPH + Oxygen + H+ <=> Lolitrem B + NADP+ + 2 H2O R10369 Terpendole I + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole I + 2 Diphosphate R10370 dimethylallyl-diphosphate:lolitriol dimethylallyl-O-transferase; Lolitriol + Dimethylallyl diphosphate <=> Lolitrem E + Diphosphate R10371 paspaline,NADPH:oxygen oxidoreductase; Paspaline + 2 NADPH + 2 H+ + 2 Oxygen <=> Paspaline B + 2 NADP+ + 3 H2O R10372 Paspaline B <=> Terpendole G R10373 paspaline,NADPH:oxygen oxidoreductase; Paspaline + Oxygen + NADPH + H+ <=> Terpendole E + NADP+ + H2O R10376 Terpendole E + 4 NADPH + 4 Oxygen + 4 H+ <=> 13-Desoxyterpendole I + Formate + 4 NADP+ + 5 H2O R10379 12-Demethyl-11,12-dehydropaspaline + 3 Oxygen + 3 NADPH + 3 H+ <=> Terpendole I + 3 NADP+ + 3 H2O R10380 dimethylallyl-diphosphate:terpendole-I dimethylallyl-O-transferase; Terpendole I + Dimethylallyl diphosphate <=> Terpendole J + Diphosphate R10381 Terpendole J + NADPH + Oxygen + H+ <=> Terpendole C + NADP+ + 2 H2O R10382 Terpendole C <=> Terpendole K R10383 Terpendole C + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole C + 2 Diphosphate R10384 Terpendole J + 2 Dimethylallyl diphosphate <=> 20,21-Diprenylterpendole J + 2 Diphosphate R10385 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase; Methyl-Co(III) corrinoid protein + Tetrahydrosarcinapterin <=> Co(I) corrinoid protein + 5-Methyl-H4SPT R10388 nitroalkane:oxygen oxidoreductase; Nitroalkane + H2O + Oxygen <=> Aldehyde + Nitrite + Hydrogen peroxide R10389 nitroalkane:oxygen oxidoreductase; Nitroalkane + H2O + Oxygen <=> Ketone + Nitrite + Hydrogen peroxide R10390 H2:polysulfide oxidoreductase; Hydrogen + Polysulfide(n) <=> Hydrogen sulfide + Polysulfide(n-1) R10391 (R)-(homo)2-citrate hydro-lyase [(-)-threo-iso(homo)2-citrate forming]; (R)-(Homo)2-citrate <=> (-)-threo-Iso(homo)2-citrate R10392 (R)-(homo)2-citrate hydro-lyase; (R)-(Homo)2-citrate <=> cis-(Homo)2-aconitate + H2O R10393 (-)-threo-iso(homo)2-citrate hydro-lyase; cis-(Homo)2-aconitate + H2O <=> (-)-threo-Iso(homo)2-citrate R10394 (R)-(homo)3-citrate hydro-lyase [(-)-threo-iso(homo)3-citrate forming]; (R)-(Homo)3-citrate <=> (-)-threo-Iso(homo)3-citrate R10395 (R)-(homo)3-citrate hydro-lyase; (R)-(Homo)3-citrate <=> cis-(Homo)3-aconitate + H2O R10396 (-)-threo-iso(homo)3-citrate hydro-lyase; cis-(Homo)3-aconitate + H2O <=> (-)-threo-Iso(homo)3-citrate R10397 7-Oxoheptanoic acid <=> 7-Mercaptoheptanoic acid R10398 versiconol acetate O-acetylhydrolase; Versiconol acetate + H2O <=> Versiconol + Acetate R10399 versiconol-acetate:NADP+ oxidoreductase; Versiconol acetate + NADP+ <=> Versiconal hemiacetal acetate + NADPH + H+ R10400 versiconol:NADP+ oxidoreductase; Versiconol + NADP+ <=> Versiconal + NADPH + H+ R10401 versiconal-hemiacetal-acetate O-acetylhydrolase; Versiconal hemiacetal acetate + H2O <=> Versiconal + Acetate R10402 versiconal hydro-lyase (versicolorin-B forming); Versiconal <=> Versicolorin B + H2O R10403 S-adenosyl-L-methionine:dihydrodemethylsterigmatocystin 6-O-methyltransferase; S-Adenosyl-L-methionine + Dihydrodemethylsterigmatocystin <=> S-Adenosyl-L-homocysteine + Dihydrosterigmatocystin R10404 S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine R10405 Terpendole E <=> Terpendole G R10406 Terpendole G <=> Terpendole B R10407 2-Amino-2-deoxy-D-gluconate + Protein N(pi)-phospho-L-histidine <=> D-Glucosaminate-6-phosphate + Protein histidine R10408 D-glucosaminate-6-phosphate ammonia-lyase; 2-amino-2-deoxy-D-gluconate 6-phosphate ammonia-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming); D-Glucosaminate-6-phosphate <=> 2-Dehydro-3-deoxy-6-phospho-D-gluconate + Ammonia R10409 S-Sulfo-L-cysteine + Glutaredoxin <=> L-Cysteine + Sulfite + Glutaredoxin disulfide R10410 beta-Paxitriol <=> Paxilline R10411 D-glucose:acceptor oxidoreductase; D-Glucose + Acceptor <=> D-Glucono-1,5-lactone + Reduced acceptor R10412 (2E,6E)-farnesol:NAD+ 1-oxidoreductase; (2E,6E)-Farnesol + NAD+ <=> 2-trans,6-trans-Farnesal + NADH + H+ R10413 L-enduracididine,2-oxoglutarate:O2 oxidoreductase (3-hydroxylating); L-Enduracididine + 2-Oxoglutarate + Oxygen <=> (3S)-3-Hydroxy-L-enduracididine + Succinate + CO2 R10414 fumitremorgin C,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha,13alpha-dihydroxyfumitremorgin C-forming); Fumitremorgin C + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 12alpha,13alpha-Dihydroxyfumitremorgin C + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10415 (3S,5S)-carbapenam-3-carboxylate,2-oxoglutarate:oxygen oxidoreductase (dehydrating); (3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O R10416 tryprostatin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Tryprostatin A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fumitremorgin C + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10417 kanamycin-A:NADP+ oxidoreductase; Kanamycin A + NADP+ <=> 2'-Dehydrokanamycin A + NADPH + H+ R10418 (S)-2-chloropropanoate:NADP+ oxidoreductase; (S)-2-Chloropropanoate + NADP+ <=> 2-Chloroacrylate + NADPH + H+ R10419 hydrogen sulfide:NAD+ oxidoreductase (CoA-dependent); Hydrogen sulfide + NAD+ <=> Sulfur + NADH + H+ R10420 GDP-beta-L-colitose:NAD+ 4-oxidoreductase (5-epimerizing); GDP-beta-L-colitose + NAD+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADH + H+ R10421 GDP-beta-L-colitose:NADP+ 4-oxidoreductase (5-epimerizing); GDP-beta-L-colitose + NADP+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H+ R10422 3alpha-hydroxysteroid:NAD+ 3-oxidoreductase; 3alpha-Hydroxysteroid + NAD+ <=> 3-Oxosteroid + NADH + H+ R10423 3alpha-hydroxysteroid:NADP+ 3-oxidoreductase; 3alpha-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+ R10424 UDP-alpha-D-kanosamine:2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase; UDP-kanosamine + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin A R10425 UDP-alpha-D-kanosamine:neamine 1-alpha-D-kanosaminyltransferase; UDP-kanosamine + Neamine <=> UDP + Kanamycin B R10426 UDP-alpha-D-kanosamine:paromamine 1-alpha-D-kanosaminyltransferase; UDP-kanosamine + Paromamine <=> UDP + Kanamycin C R10427 UDP-alpha-D-kanosamine:2'-deamino-2'-hydroxyparomamine 1-alpha-D-kanosaminyltransferase; UDP-kanosamine + 2'-Deamino-2'-hydroxyparomamine <=> UDP + Kanamycin X R10428 an aldopyranose:NAD+ 1-oxidoreductase; Aldopyranose + NAD+ <=> Aldono-1,5-lactone + NADH + H+ R10429 an aldopyranose:NADP+ 1-oxidoreductase; Aldopyranose + NADP+ <=> Aldono-1,5-lactone + NADPH + H+ R10430 S-methyl-L-methionine:L-selenocysteine Se-methyltransferase; S-Methyl-L-methionine + L-Selenocysteine <=> L-Methionine + Se-Methyl-L-selenocysteine R10431 S-adenosyl-L-methionine:2-oxo-3-phenylpropanoate C3-methyltransferase; S-Adenosyl-L-methionine + Phenylpyruvate <=> S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate R10432 UDP-alpha-D-galactose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-beta-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R10433 UDP-alpha-D-galactose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol beta-1,4-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R10434 UDP-alpha-D-glucose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol beta-1,3-glucosyltransferase; UDP-glucose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R10435 UDP-N-acetyl-alpha-D-galactosamine:N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol alpha-1,3-N-acetyl-D-galactosyltransferase; UDP-N-acetyl-D-galactosamine + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol <=> UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol R10436 UDP-alpha-D-galactose:alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol beta-1,3-galactosyltransferase; UDP-alpha-D-galactose + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> UDP + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol R10437 7-(hydroxymethyl)bacteriochlorophyllide c:S-adenosyl-L-methionine oxidoreductase (C-7(1)-hydroxylating); S-Adenosyl-L-methionine + 7-(Hydroxymethyl)bacteriochlorophyllide c + H2O <=> 7-(Dihydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine R10438 hydrogen sulfide:NADP+ oxidoreductase (CoA-dependent); Hydrogen sulfide + NADP+ <=> Sulfur + NADPH + H+ R10439 GDP-beta-L-fucose:beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol alpha-1,2-fucosyltransferase; GDP-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol R10440 UDP-alpha-D-galactose:alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol alpha-1,3-galactosyltransferase; UDP-alpha-D-galactose + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol <=> UDP + alpha-D-Gal-(1->3)-(alpha-L-Fuc-(1->2))-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol R10441 CDP-2,3-bis-(O-phytanyl)-sn-glycerol:L-serine 2,3-bis-(O-phytanyl)-sn-glycerol phosphotransferase; CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-Serine <=> CMP + 2,3-Bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine R10442 NDP + H2O <=> Nucleoside 5'-phosphate + Orthophosphate R10443 nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming); Nucleoside triphosphate + 2 H2O <=> Nucleoside 5'-phosphate + 2 Orthophosphate R10444 caldariellaquinol:O2 oxidoreductase (H+-transporting); 2 Caldariellaquinol + Oxygen + n H+ <=> 2 Caldariellaquinone + 2 H2O + n H+ R10445 fumitremorgin B,2-oxoglutarate:oxygen oxidoreductase (verruculogen-forming); Fumitremorgin B + 2-Oxoglutarate + 2 Oxygen + Reduced acceptor <=> Verruculogen + Succinate + CO2 + H2O + Acceptor R10446 L-asparagine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating); L-Asparagine + 2-Oxoglutarate + Oxygen <=> (2S,3S)-3-Hydroxyasparagine + Succinate + CO2 R10447 S-adenosyl-L-methionine:benzoate O-methyltransferase; S-Adenosyl-L-methionine + Benzoate <=> S-Adenosyl-L-homocysteine + Methyl benzoate R10448 S-adenosyl-L-methionine:salicylate 1-O-methyltransferase; S-Adenosyl-L-methionine + Salicylate <=> S-Adenosyl-L-homocysteine + Methyl salicylate R10449 S-adenosyl-L-methionine:gibberellin A9 O-methyltransferase; S-Adenosyl-L-methionine + Gibberellin A9 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A9 R10450 S-adenosyl-L-methionine:gibberellin A4 O-methyltransferase; S-Adenosyl-L-methionine + Gibberellin A4 <=> S-Adenosyl-L-homocysteine + Methyl gibberellin A4 R10451 S-adenosyl-L-methionine:anthranilate O-methyltransferase; S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + O-Methyl anthranilate R10452 S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase; S-Adenosyl-L-methionine + Indole-3-acetate <=> S-Adenosyl-L-homocysteine + Methyl (indol-3-yl)acetate R10453 3-dimethylallyl-4-hydroxybenzoate:3-amino-4,7-dihydroxycoumarin ligase (AMP-forming); ATP + 3-Dimethylallyl-4-hydroxybenzoate + 3-Amino-4,7-dihydroxycoumarin <=> AMP + Diphosphate + 8-Demethylnovobiocic acid R10454 S-adenosyl-L-methionine:8-demethylnovobiocic acid C8-methyltransferase; S-Adenosyl-L-methionine + 8-Demethylnovobiocic acid <=> S-Adenosyl-L-homocysteine + Novobiocic acid R10455 S-adenosyl-L-methionine:L-histidine-[translation elongation factor 2] 2-[(3S)-3-amino-3-carboxypropyl]transferase; S-Adenosyl-L-methionine + L-Histidine-[translation elongation factor 2] <=> 5'-Methylthioadenosine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine R10456 dimethylallyl-diphosphate:brevianamide-F tert-dimethylallyl-C-2-transferase; Dimethylallyl diphosphate + Brevianamide F <=> Diphosphate + Deoxybrevianamide E R10457 dimethylallyl-diphosphate:12alpha,13alpha-dihydroxyfumitremorgin C dimethylallyl-N-1-transferase; Dimethylallyl diphosphate + 12alpha,13alpha-Dihydroxyfumitremorgin C <=> Diphosphate + Fumitremorgin B R10459 dTDP-5-dimethyl-L-lyxose:NAD+ 4-oxidoreductase; dTDP-4-oxo-5-C-methyl-L-rhamnose + NADH + H+ <=> dTDP-5-dimethyl-L-lyxose + NAD+ R10460 GDP-4-amino-4,6-dideoxy-alpha-D-mannose:2-oxoglutarate aminotransferase; GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate <=> GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate R10461 O-acetyl-L-serine:hydroxyurea 2-amino-2-carboxyethyltransferase; O-Acetyl-L-serine + Hydroxyurea <=> O-Ureido-L-serine + Acetate R10462 ATP:GTP adenylyltransferase (cyclizing); ATP + GTP <=> 2 Diphosphate + Cyclic GMP-AMP R10463 ATP:L-threonyl,bicarbonate adenylyltransferase; L-Threonine + ATP + HCO3- + H+ <=> L-Threonylcarbamoyladenylate + Diphosphate + H2O R10464 CDP-2,3-bis-(O-phytanyl)-sn-glycerol:1L-myo-inositol 1-phosphate 1-sn-archaetidyltransferase; CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1D-myo-Inositol 3-phosphate <=> CMP + 1-Archaetidyl-1D-myo-inositol 3-phosphate R10465 UDP-N-acetyl-alpha-D-galactosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-galactosaminephosphotransferase; UDP-N-acetyl-D-galactosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol R10466 N(omega)-hydroxy-L-arginine amidinohydrolase; N(omega)-Hydroxyarginine + H2O <=> L-Ornithine + Hydroxyurea R10467 2-heptyl-4(1H)-quinolone,NADH:oxygen oxidoreductase (3-hydroxylating); 2-Heptyl-4(1H)-quinolone + NADH + H+ + Oxygen <=> 2-Heptyl-3-hydroxy-quinolone + NAD+ + H2O R10468 protoheme,hydrogen-donor:oxygen oxidoreductase (delta-methene-oxidizing, hydroxylating); Heme + 5 Reduced acceptor + 4 Oxygen <=> 5-Oxo-delta-bilirubin + Fe2+ + Formaldehyde + 5 Acceptor + 4 H2O R10469 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate hydro-lyase (cyclizing, 3-amino-4-hydroxybenzoate-forming); 2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O R10470 O-ureido-D-serine cyclo-ligase (D-cycloserine-forming); O-Ureido-D-serine + ATP + H2O <=> Cycloserine + CO2 + Ammonia + ADP + Orthophosphate R10472 S-adenosyl-L-methionine:emodin 8-O-methyltransferase; S-Adenosyl-L-methionine + Emodin <=> S-Adenosyl-L-homocysteine + Questin R10473 acetyl-CoA:benzylalcohol O-acetyltransferase; Acetyl-CoA + Benzyl alcohol <=> CoA + Benzyl acetate R10474 acetyl-CoA:cinnamyl alcohol O-acetyltransferase; Acetyl-CoA + Cinnamyl alcohol <=> CoA + Cinnamyl acetate R10475 5'-oxoaverantin hydro-lyase [(1'S,5'S)-averufin forming]; 5'-Oxoaverantin <=> (1'S,5'S)-Averufin + H2O R10476 (1'S,5'S)-Averufin + NADPH + H+ + Oxygen <=> 1'-Hydroxyversicolorone + NADP+ + H2O R10477 1'-Hydroxyversicolorone + NADPH + H+ + Oxygen <=> Versiconal hemiacetal acetate + NADP+ + H2O R10478 Versicolorone + NADPH + H+ + Oxygen <=> Versiconol acetate + NADP+ + H2O R10479 Versicolorin B + Oxygen + NADPH + H+ <=> Versicolorin A + NADP+ + 2 H2O R10480 Versicolorin B <=> Dihydrodemethylsterigmatocystin R10481 Versicolorin A <=> 6-Demethylsterigmatocystin R10482 Dihydro-O-methylsterigmatocystin <=> Aflatoxin G2 R10483 O-Methylsterigmatocystin <=> Aflatoxin G1 R10484 palmitoyl-CoA:[protein]-L-cysteine S-palmitoyltransferase; Palmitoyl-CoA + [Protein]-L-cysteine <=> S-Palmitoylprotein + CoA R10485 malonyl-CoA:(S)-1-pyrroline-5-carboxylate malonyltransferase (cyclizing); Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate + H2O <=> CoA + (2S,5S)-trans-Carboxymethylproline + CO2 R10486 maltose 6'-phosphate phosphohydrolase; Maltose 6'-phosphate + H2O <=> Maltose + Orthophosphate R10487 (S)-2-(4-chloro-2-dichlorophenoxy)propanoate,2-oxoglutarate:oxygen oxidoreductase (pyruvate-forming); (S)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2 R10488 (2S)-2-amino-3-[(carbamoylamino)oxy]propanoate 2-epimerase; O-Ureido-L-serine <=> O-Ureido-D-serine R10491 S-adenosyl-L-methionine:gamma-tocotrienol 5-O-methyltransferase; S-Adenosyl-L-methionine + gamma-Tocotrienol <=> S-Adenosyl-L-homocysteine + alpha-Tocotrienol R10492 S-adenosyl-L-methionine:delta-tocotrienol 5-O-methyltransferase; S-Adenosyl-L-methionine + delta-Tocotrienol <=> S-Adenosyl-L-homocysteine + beta-Tocotrienol R10493 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (kunzeaol forming); trans,trans-Farnesyl diphosphate + H2O <=> Kunzeaol + Diphosphate R10494 6-tuliposide-A D-glucose-lyase (tulipalin-A-forming); 6-Tuliposide A <=> Tulipalin A + D-Glucose R10495 S-adenosyl-L-methionine:anthranilate:L-phenylalanine ligase (cyclopeptine forming); 2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine <=> Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine R10496 agmatine:[tRNA(Ile2)]-cytidine34 ligase; ATP + Agmatine + [tRNA(Ile2)]-cytidine34 + H2O <=> [tRNA(Ile2)]-2-agmatinylcytidine34 + AMP + 2 Orthophosphate R10497 S-adenosyl-L-methionine:25S rRNA (adenine2142-N1)-methyltransferase; S-adenosyl-L-methionine:25S rRNA (adenine645-N1)-methyltransferase; S-Adenosyl-L-methionine + Adenine in rRNA <=> S-Adenosyl-L-homocysteine + N1-Methyladenine in rRNA R10498 S-adenosyl-L-methionine:tRNAPhe [7-[(3S)-(3-amino-3-carboxypropyl)-4-demethyl]wyosine-N4]-methyltransferase; S-Adenosyl-L-methionine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe) <=> S-Adenosyl-L-homocysteine + 7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) R10499 L-phenylalanine:2-oxo-acid aminotransferase; L-Phenylalanine + 2-Oxo acid <=> Phenylpyruvate + L-Amino acid R10500 acetyl-CoA:phenylpyruvate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); Phenylpyruvate + Acetyl-CoA + H2O <=> 2-Benzylmalic acid + CoA R10501 2-benzylmalate hydro-lyase (3-benzylmalate-forming); 2-Benzylmalic acid <=> 3-Benzylmalic acid R10502 3-benzylmalate:NAD+ oxidoreductase (decarboxylating); 3-Benzylmalic acid + NAD+ <=> 2-Oxo-4-phenylbutyric acid + CO2 + NADH + H+ R10503 L-amino acid:2-oxo-4-phenylbutyric-acid aminotransferase; 2-Oxo-4-phenylbutyric acid + L-Amino acid <=> L-Homophenylalanine + 2-Oxo acid R10504 meso-2,3-butanediol:NAD+ oxidoreductase [(S)-acetoin forming]; meso-2,3-Butanediol + NAD+ <=> (S)-Acetoin + NADH + H+ R10505 meso-2,3-butanediol:NAD+ oxidoreductase [(R)-acetoin forming]; meso-2,3-Butanediol + NAD+ <=> (R)-Acetoin + NADH + H+ R10506 (S)-2-Acetolactate + Acceptor <=> Diacetyl + CO2 + Reduced acceptor R10507 L-proline:(acceptor) oxidoreductase; L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2 R10508 lycopene cyclase; 3,4-Dehydrolycopene <=> Torulene R10509 (-)-bornyl-diphosphate lyase (decyclizing); Geranyl diphosphate <=> (-)-Bornyl diphosphate R10510 protoheme,hydrogen-donor:oxygen oxidoreductase (beta-methene-oxidizing, hydroxylating); Heme + 5 Reduced acceptor + 4 Oxygen <=> 15-Oxo-beta-bilirubin + Fe2+ + Formaldehyde + 5 Acceptor + 4 H2O R10511 testosterone monooxygenase (17beta-estradiol-forming); Testosterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Estradiol-17beta + Formate + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R10512 hydrogen sulfide,polysulfide:NADP+ oxidoreductase; Hydrogen sulfide + Polysulfide(n) + NADP+ <=> Polysulfide(n+1) + NADPH + H+ R10514 acetyl-CoA:GDP-4-amino-4,6-dideoxy-alpha-D-mannose N-acetyltransferase; Acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose R10515 androst-4-ene-3,17-dione monooxygenase (estrone-forming); Androstenedione + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Estrone + Formate + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R10516 2-oxocarboxylate:ferredoxin 2-oxidoreductase (decarboxylating, CoA-acylating); 2-Oxo acid + CoA + 2 Oxidized ferredoxin <=> Acyl-CoA + CO2 + 2 Reduced ferredoxin + 2 H+ R10517 NADH:oxygen oxidoreductase (H2O-forming); 2 NADH + 2 H+ + Oxygen <=> 2 NAD+ + 2 H2O R10518 NADPH:oxygen oxidoreductase (H2O-forming); 2 NADPH + 2 H+ + Oxygen <=> 2 NADP+ + 2 H2O R10519 D-glucose-6-phosphate:NAD+ oxidoreductase; D-Glucose 6-phosphate + NAD+ <=> 3-Dehydro-D-glucose 6-phosphate + NADH + H+ R10520 D-glucose-6-phosphate:NAD+ 1-oxidoreductase; D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+ R10521 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing); 2-Amino-5-chlorophenol + Oxygen <=> 2-Amino-5-chloromuconate 6-semialdehyde R10522 tRNAPhe 7-(3-amino-3-carboxypropyl)wyosine37,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating); 7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + 2-Oxoglutarate + Oxygen <=> 7-(2-Hydroxy-3-amino-3-carboxypropyl)wyosine in tRNA(Phe) + Succinate + CO2 R10523 S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase; S-Adenosyl-L-methionine + L-Histidine <=> S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine R10524 S-adenosyl-L-methionine:Nalpha-methyl-L-histidine Nalpha-methyltransferase; S-Adenosyl-L-methionine + Nalpha-Methylhistidine <=> S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine R10525 NDP-alpha-D-glucose:D-glucose 1-alpha-D-glucosyltransferase; NDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + NDP R10526 isovaleryl-CoA:S-adenosyl-L-methionine isovaleryltranserase (lactone-forming, methylthioadenosine-releasing); 3-Methylbutanoyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-Isovaleryl-L-homoserine lactone R10527 (S)-2-(4-chloro-2-methylphenoxy)propanoate,2-oxoglutarate:oxygen oxidoreductase (pyruvate-forming); (S)-2-(4-Chloro-2-methylphenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2 R10528 (R)-2-hydroxycarboxylate:NADP+ oxidoreductase; (R)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+ R10529 4-coumaroyl-CoA:S-adenosyl-L-methionine trans-4-coumaroyltranserase (lactone-forming, methylthioadenosine-releasing); p-Coumaroyl-CoA + S-Adenosyl-L-methionine <=> CoA + 5'-Methylthioadenosine + N-(4-Coumaroyl)-L-homoserine lactone R10530 protodioscin glucohydrolase; Protodioscin + H2O <=> 26-Deglucoprotodioscin + D-Glucose R10531 ATP phosphohydrolase (ABC-type, tungstate-importing); ATP + H2O + Tungstate <=> ADP + Orthophosphate + Tungstate R10532 L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming); L-Galactonate <=> 2-Dehydro-3-deoxy-L-galactonate + H2O R10533 geranylgeranyl-diphosphate diphosphate-lyase [(E,E)-geranyllinalool-forming]; Geranylgeranyl diphosphate + H2O <=> (E,E)-Geranyllinalool + Diphosphate R10534 carbon-disulfide hydrogen-sulfide-lyase (carbonyl-sulfide-forming); Carbon disulfide + H2O <=> Carbonyl sulfide + Hydrogen sulfide R10535 carbonyl-sulfide hydrogen-sulfide-lyase (decarboxylating); Carbonyl sulfide + H2O <=> CO2 + Hydrogen sulfide R10536 dTDP-alpha-D-fucopyranose furanomutase; dTDP-D-fucose <=> dTDP-alpha-D-fucofuranose R10537 RNA-3'-phosphate:RNA ligase (cyclizing, GMP-forming); GTP + RNA 3'-terminal-phosphate <=> GMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate R10538 carbon-disulfide hydrogen-sulfide-lyase (decarboxylating); Carbon disulfide + 2 H2O <=> CO2 + 2 Hydrogen sulfide R10539 (R)-2-(4-chloro-2-methylphenoxy)propanoate,2-oxoglutarate:oxygen oxidoreductase (pyruvate-forming); Mecoprop-P + 2-Oxoglutarate + Oxygen <=> 4-Chloro-2-methylphenol + Pyruvate + Succinate + CO2 R10540 dammarenediol-II,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12beta-hydroxylating); Dammarenediol-II + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Protopanaxadiol + [Oxidized NADPH---hemoprotein reductase] + H2O R10541 Carbamoyl phosphate + ATP + H2O <=> Diphosphate + O-Carbamoyladenylate + Orthophosphate R10542 (R)-2-(4-chloro-2-dichlorophenoxy)propanoate,2-oxoglutarate:oxygen oxidoreductase (pyruvate-forming); (R)-(2,4-Dichlorophenoxy)propanoate + 2-Oxoglutarate + Oxygen <=> 2,4-Dichlorophenol + Pyruvate + Succinate + CO2 R10543 tobramycin:carbamoyl phosphate ligase (AMP,phosphate-forming); O-Carbamoyladenylate + Tobramycin <=> AMP + Nebramycin 5' R10544 kanamycin A:carbamoyl phosphate ligase (AMP,phosphate-forming); O-Carbamoyladenylate + Kanamycin A <=> AMP + 6''-O-Carbamoylkanamycin A R10545 aclacinomycin T acylhydrolase; Aclacinomycin T + H2O <=> 15-Demethylaclacinomycin T + Methanol R10546 N7-methyl-GMP phosphohydrolase; 7-Methylguanosine 5'-phosphate + H2O <=> N7-Methylguanosine + Orthophosphate R10547 kanosamine-6-phosphate phosphohydrolase; Kanosamine 6-phosphate + H2O <=> Kanosamine + Orthophosphate R10548 ATP:1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 5-phosphotransferase; ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate R10549 long-chain-aldehyde:NADP+ oxidoreductase (protein thioester-forming); Long-chain aldehyde + [Protein]-L-cysteine + NADP+ <=> [Protein]-S-(long-chain-acyl)-L-cysteine + NADPH + H+ R10550 2-dehydro-3-deoxy-L-galactonate L-glyceraldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-L-galactonate <=> Pyruvate + L-Glyceraldehyde R10551 long-chain-aldehyde,FMNH2:oxygen oxidoreductase (1-hydroxylating, luminescing); Long-chain aldehyde + Reduced FMN + Oxygen <=> Long-chain fatty acid + hn + FMN + H2O R10552 tRNA(Phe)-N1-methylguanine,pyruvate acetaldehyde-lyase [tRNA(Phe)-4-demethylwyosine-forming, decarboxylating, dehydrating]; N1-Methylguanine in tRNA(Phe) + Pyruvate + S-Adenosyl-L-methionine <=> 4-Demethylwyosine in tRNA(Phe) + L-Methionine + 5'-Deoxyadenosine + CO2 + H2O R10553 N-acetyl-L-cysteine-S-conjugate amidohydrolase (carboxylate-forming); S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate R10554 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase; N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> N-Acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol R10555 alpha-D-ribose 1,5-bisphosphate aldose-ketose-isomerase; D-Ribose 1,5-bisphosphate <=> D-Ribulose 1,5-bisphosphate R10556 (2S,5S)-5-carboxymethylproline cyclo-ligase (AMP-forming); ATP + (2S,5S)-trans-Carboxymethylproline <=> AMP + Diphosphate + (3S,5S)-Carbapenam-3-carboxylic acid R10557 9-cis-beta-carotene:O2 oxidoreductase (9',10'-cleaving); 9-cis-beta-Carotene + Oxygen <=> 9-cis-10'-Apo-beta-carotenal + beta-Ionone R10558 9-cis-10'-apo-beta-carotenal:O2 oxidoreductase (14,15-cleaving, carlactone-forming); 9-cis-10'-Apo-beta-carotenal + 2 Oxygen <=> Carlactone + (2E,4E,6E)-7-Hydroxy-4-methylhepta-2,4,6-trienal R10559 all-trans-beta-carotene:O2 oxidoreductase (9',10'-cleaving); beta-Carotene + Oxygen <=> all-trans-10'-Apo-beta-carotenal + beta-Ionone R10560 all-trans-10'-apo-beta-carotenal:O2 oxidoreductase (13,14-cleaving); all-trans-10'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + (2E,4E,6E)-4-Methylocta-2,4,6-trienedial R10561 ATP:phosphomevalonate carboxy-lyase (adding ATP; isopentenyl-phosphate-forming); (R)-5-Phosphomevalonate + ATP <=> Isopentenyl phosphate + ADP + Orthophosphate + CO2 R10562 (6E,10E)-geranyllinalool,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (E,E)-Geranyllinalool + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (E,E)-4,8,12-Trimethyltrideca-1,3,7,11-tetraene + But-3-en-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10563 glycerol:NADP+ oxidoreductase (D/L-glyceraldehyde-forming); L-Glyceraldehyde + NADPH + H+ <=> Glycerol + NADP+ R10564 (5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase; (S)-5-Amino-3-oxohexanoic acid + Acetyl-CoA <=> L-3-Aminobutyryl-CoA + Acetoacetate R10565 L-galactonate:NAD+ oxidoreductase; L-Galactonate + NAD+ <=> D-Galacturonate + NADH + H+ R10566 beta-Paxitriol <=> Penitrem D R10569 beta-Paxitriol <=> Janthitrem C R10570 12-Demethyl-11,12-dehydropaspaline <=> Terpendole B R10571 Terpendole B <=> 13-Desoxyterpendole I R10572 quinol:coenzyme-F420 oxidoreductase; Hydroquinone + Coenzyme F420 <=> Quinone + Reduced coenzyme F420 R10573 dTDP-6-deoxy-alpha-D-allose:NADP+ oxidoreductase; dTDP-6-deoxy-D-allose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-allose + NADPH + H+ R10574 secondary-alcohol:coenzyme F420 oxidoreductase; Secondary alcohol + Coenzyme F420 <=> Ketone + Reduced coenzyme F420 R10575 (R)-2-hydroxyglutarate:acceptor 2-oxidoreductase; (R)-2-Hydroxyglutarate + Acceptor <=> 2-Oxoglutarate + Reduced acceptor R10576 oleate:oxygen (10S)-oxidoreductase; (9Z)-Octadecenoic acid + Oxygen <=> (8E,10S)-10-Hydroperoxyoctadeca-8-enoate R10577 linoleate:oxygen (10S)-oxidoreductase; Linoleate + Oxygen <=> (8E,10S,12Z)-10-Hydroperoxyoctadeca-8,12-dienoate R10578 alpha-linolenate:oxygen (10S)-oxidoreductase; (9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> (8E,10S,12Z,15Z)-10-Hydroperoxyoctadeca-8,12,15-trienoate R10579 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose hydrolase; 4-O-(beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O <=> 4-O-(beta-L-Arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-Arabinofuranosyl-(1->2)-beta-L-arabinofuranose R10580 avenacoside B 26-beta-D-glucohydrolase; Avenacoside B + H2O <=> 26-Desgluco-avenacoside B + D-Glucose R10581 3-O-[alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc]diosgenin hydrolase (diosgenin-forming); Dioscin + 3 H2O <=> D-Glucose + 2 L-Rhamnose + Diosgenin R10582 3-O-[alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc]diosgenin (3-O-beta-D-Glc-diosgenin-forming); Dioscin + 2 H2O <=> 2 L-Rhamnose + Diosgenin 3-O-beta-D-glucopyranoside R10583 chorismate pyruvate-hydrolase; Chorismate + H2O <=> (4R,5R)-4,5-Dihydroxycyclohexa-1(6),2-diene-1-carboxylate + Pyruvate R10584 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-copaene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Copaene + Diphosphate R10585 (+)-copaly-diphosphate diphosphate-lyase (cyclizing, miltiradiene-forming); Copalyl diphosphate <=> Miltiradiene + Diphosphate R10586 S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-carboxypropyl]wyosine37-O}-methyltransferase; 7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine R10587 S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methyltransferase (carbon dioxide-adding); 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine R10588 S-adenosyl-L-methionine:6-hydroxytryprostatin B O-methyltransferase; S-Adenosyl-L-methionine + 6-Hydroxytryprostatin B <=> S-Adenosyl-L-homocysteine + Tryprostatin A R10589 anthraniloyl-CoA:3-oxodecanoate C-anthraniloyltransferase (decarboxylating); 3-Oxodecanoate + Anthraniloyl-CoA <=> CoA + 2-Heptyl-4(1H)-quinolone + CO2 + H2O R10590 octanoyl-CoA:2-aminobenzoylacetate octanoyltransferase; Octanoyl-CoA + L-Cysteinyl-protein <=> S-Octanoyl-L-cysteinyl-protein + CoA R10591 protopanaxadiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); Protopanaxadiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Protopanaxatriol + [Oxidized NADPH---hemoprotein reductase] + H2O R10593 4-hydroxy-2,5-dimethylfuran-3(2H)-one:NADP+ oxidoreductase; 4-Hydroxy-2,5-dimethylfuran-3(2H)-one + NADP+ <=> 4-Hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H+ R10594 UDP-alpha-D-glucose:vancomycin aglycone 48-O-beta-glucosyltransferase; UDP-glucose + Vancomycin aglycone <=> UDP + Desvancosaminyl-vancomycin R10595 dTDP-L-4-epi-vancosamine:desvancosaminyl-vancomycin vancosaminyltransferase; dTDP-L-epivancosamine + Desvancosaminyl-vancomycin <=> dTDP + Chloroorienticin B R10596 UDP-N-acetyl-alpha-D-glucosamine:alpha-D-mannosyl-threonyl-[protein] 4-beta-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein] <=> UDP + 3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] R10597 chorismate pyruvate-lyase (3-hydroxybenzoate-forming); Chorismate <=> 3-Hydroxybenzoate + Pyruvate R10598 (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-beta-chamigrene-forming); trans,trans-Farnesyl diphosphate <=> (+)-beta-Chamigrene + Diphosphate R10599 (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-thujopsene-forming); trans,trans-Farnesyl diphosphate <=> (+)-Thujopsene + Diphosphate R10600 acetyl-CoA:itaconate CoA-transferase; Acetyl-CoA + Itaconate <=> Acetate + Itaconyl-CoA R10601 cyclohexane-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase; Cyclohexane-1-carbonyl-CoA + Electron-transferring flavoprotein <=> Cyclohex-1-ene-1-carbonyl-CoA + Reduced electron-transferring flavoprotein R10602 reduced coenzyme F420:oxygen oxidoreductase; 2 Reduced coenzyme F420 + Oxygen <=> 2 Coenzyme F420 + 2 H2O R10603 coenzyme F420:ferredoxin oxidoreductase; Reduced coenzyme F420 + 2 Oxidized ferredoxin <=> Coenzyme F420 + 2 Reduced ferredoxin + 2 H+ R10604 D-Galactono-1,5-lactone + H2O <=> D-Galactonate R10605 S-adenosyl-L-methionine:(S)-reticuline 7-O-methyltransferase; (S)-Reticuline + S-Adenosyl-L-methionine <=> (S)-Laudanine + S-Adenosyl-L-homocysteine R10606 S-adenosyl-L-methionine:(R)-reticuline 7-O-methyltransferase; (R)-Reticuline + S-Adenosyl-L-methionine <=> (-)-Laudanidine + S-Adenosyl-L-homocysteine R10607 UDP-glucose:ginsenoside-Rd beta-1,6-glucosyltransferase; UDP-glucose + Ginsenoside Rd <=> UDP + Ginsenoside Rb1 R10608 nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase; Nicotinate D-ribonucleotide + Phenol <=> Nicotinate + Phenyl 5-phospho-alpha-D-ribofuranoside + H+ R10609 UDP-alpha-D-xylose:kaempferol 3-O-D-xylosyltransferase; UDP-D-xylose + Kaempferol <=> UDP + Kaempferol 3-O-beta-D-xyloside R10610 O-phospho-L-serine:thiocarboxy-[sulfur-carrier protein] 2-amino-2-carboxyethyltransferase; O-Phospho-L-serine + Thiocarboxy-[sulfur-carrier protein] <=> [Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + Orthophosphate R10611 S-adenosyl-L-methionine:tRNA(Phe) (4-demethylwyosine37-C7)-[(3S)-3-amino-3-carboxypropyl]transferase; S-Adenosyl-L-methionine + 4-Demethylwyosine in tRNA(Phe) <=> 5'-Methylthioadenosine + 7-[(3S)-3-Amino-3-carboxypropyl]-4-demethylwyosine in tRNA(Phe) R10612 (S)-malyl-CoA hydrolase; L-Malyl-CoA + H2O <=> (S)-Malate + CoA R10613 FAD:protein riboflavin-5'-phosphate transferase; FAD + [Protein]-L-threonine <=> [Protein]-FMN-L-Threonine + AMP R10614 acetyl-CoA:oxalate CoA-transferase; Acetyl-CoA + Oxalate <=> Acetate + Oxalyl-CoA R10615 D-glyceraldehyde:NADP+ oxidoreductase; D-Glyceraldehyde + NADP+ + H2O <=> D-Glycerate + NADPH + H+ R10616 2-dehydro-3-deoxy-D-galactonate D-glyceraldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-D-galactonate <=> Pyruvate + D-Glyceraldehyde R10617 mycothiol S-conjugate amidohydrolase (N-acetyl-L-cysteine-S-conjugate-forming); Mycothiol S-conjugate + H2O <=> S-Substituted N-acetyl-L-cysteine + 1-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol R10619 D-galactose 1-epimerase; aldose 1-epimerase; D-Galactose <=> alpha-D-Galactose R10620 UDP-N-acetyl-alpha-D-galactosamine:N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-threonyl-[protein] 3-beta-N-acetyl-D-galactosaminyltransferase; 3-O-[N-Acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-D-galactosamine <=> 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP R10621 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); N-Acyl-aromatic-L-amino acid + H2O <=> Aromatic amino acid + Carboxylate R10622 alpha-D-galactose-1-phosphate phosphohydrolase; alpha-D-Galactose 1-phosphate + H2O <=> D-Galactose + Orthophosphate R10623 delta-tocotrienol lyase (decyclizing); delta-Tocotrienol <=> 6-Geranylgeranyl-2-methylbenzene-1,4-diol R10624 gamma-tocotrienol lyase (decyclizing); gamma-Tocotrienol <=> 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol R10625 (R)-2-hydroxyacid:quinone oxidoreductase; (R)-2-Hydroxyacid + Quinone <=> 2-Oxo acid + Hydroquinone R10626 narbomycin,reduced ferredoxin:oxygen oxidoreductase (neopikromycin-forming); Narbomycin + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Neopikromycin + 2 Oxidized ferredoxin + H2O R10627 narbomycin,reduced ferredoxin:oxygen oxidoreductase (novapikromyin-forming); Narbomycin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Novapikromycin + 4 Oxidized ferredoxin + 2 H2O R10628 10-deoxymethymycin,reduced ferredoxin:oxygen oxidoreductase (novamethymycin-forming); 10-Deoxymethymycin + 4 Reduced ferredoxin + 4 H+ + 2 Oxygen <=> Novamethymycin + 4 Oxidized ferredoxin + 2 H2O R10629 NAD+ nicotinamide-lyase (cyclic-ADP-ribose-forming); NAD+ <=> Cyclic ADP-ribose + Nicotinamide + H+ R10630 cyclic-ADP-ribose hydrolase; Cyclic ADP-ribose + H2O <=> ADP-ribose R10631 NADP+ nicotinamide-lyase (2'-phospho-cyclic-ADP-ribose-forming); NADP+ <=> 2'-Phospho-cyclic ADP-ribose + Nicotinamide + H+ R10632 NAADP nicotinate-lyase (2'-phospho-cyclic-ADP-ribose-forming); 2'-Phospho-cyclic ADP-ribose + Nicotinate + H+ <=> Nicotinic acid adenine dinucleotide phosphate R10633 NAD+ + Histone N6-acetyl-L-lysine + H2O <=> Nicotinamide + Histone-L-lysine + O-Acetyl-ADP-ribose + H+ R10634 NAD+ + Protein N6-acetyl-L-lysine + H2O <=> Nicotinamide + Protein lysine + O-Acetyl-ADP-ribose + H+ R10635 NADH:oxygen oxidoreductase (H2O2-forming, epimerising); alpha-NADH + H+ + Oxygen <=> NAD+ + Hydrogen peroxide R10636 NADPH:oxygen oxidoreductase (H2O2-forming, epimerising); alpha-NADPH + H+ + Oxygen <=> NADP+ + Hydrogen peroxide R10637 (Z)-phenylacetaldehyde-oxime,NADPH:oxygen oxidoreductase; (Z)-Phenylacetaldehyde oxime + NADPH + Oxygen + H+ <=> Mandelonitrile + NADP+ + 2 H2O R10638 UDP-D-glucose:(R)-mandelonitrile beta-D-glucosyltransferase; Mandelonitrile + UDP-glucose <=> Prunasin + UDP R10639 Prunasin + UDP-glucose <=> Amygdalin + UDP R10640 succinyl-CoA:(R)-citramalate CoA-transferase; Succinyl-CoA + (R)-2-Methylmalate <=> Succinate + (3R)-Citramalyl-CoA R10641 succinyl-CoA:(R)-malate CoA-transferase; Succinyl-CoA + (R)-Malate <=> Succinate + (R)-Malyl-CoA R10643 (E)-4-(trimethylammonio)but-2-enoyl-CoA:L-carnitine CoA-transferase; (E)-4-(Trimethylammonio)but-2-enoyl-CoA + L-Carnitine <=> (E)-4-(Trimethylammonio)but-2-enoate + L-Carnitinyl-CoA R10644 4-trimethylammoniobutanoyl-CoA:L-carnitine CoA-transferase; 4-Trimethylammoniobutanoyl-CoA + L-Carnitine <=> 4-Trimethylammoniobutanoate + L-Carnitinyl-CoA R10645 tRNA (N6-dimethylallyladenosine):sulfur-donor,S-adenosyl-L-methionine C2-methylthiotransferase; tRNA containing 6-isopentenyladenosine + Sulfur donor + 2 S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine R10646 tRNA containing 6-isopentenyladenosine + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-dimethylallyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine R10647 2-Thio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-dimethylallyladenine in tRNA + S-Adenosyl-L-homocysteine R10648 L-threonylcarbamoyladenylate:adenine in tRNA N6-L-threonylcarbamoyltransferase; L-Threonylcarbamoyladenylate + tRNA adenine <=> AMP + N6-L-Threonylcarbamoyladenine in tRNA R10649 tRNA (N6-L-threonylcarbamoyladenosine37):sulfur-donor,S-adenosyl-L-methionine C2-methylthiotransferase; N6-L-Threonylcarbamoyladenine in tRNA + Sulfur donor + 2 S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine R10650 N6-L-Threonylcarbamoyladenine in tRNA + Sulfur donor + S-Adenosyl-L-methionine <=> 2-Thio-N6-L-threonylcarbamoyladenine in tRNA + L-Methionine + 5'-Deoxyadenosine R10651 2-Thio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-methionine <=> 2-Methylthio-N6-L-threonylcarbamoyladenine in tRNA + S-Adenosyl-L-homocysteine R10652 [ribosomal protein uS12]-L-aspartate:sulfur-donor,S-adenosyl-L-methionine C3-methylthiotransferase; [Ribosomal protein uS12]-L-aspartate + Sulfur donor + 2 S-Adenosyl-L-methionine + Reduced acceptor <=> [Ribosomal protein uS12]-3-methylthioaspartate + S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + Acceptor R10655 3'-phosphoadenylyl-sulfate:desulfo-A47934 sulfotransferase; 3'-Phosphoadenylyl sulfate + Desulfo-A47934 <=> Adenosine 3',5'-bisphosphate + A47934 R10656 20-oxo-5-O-beta-mycaminosyltylactone,reduced ferredoxin:oxygen oxidoreductase (23-hydroxylating); 20-Oxo-5-O-beta-mycaminosyltylactone + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 5-O-beta-D-Mycaminosyltylonolide + 2 Oxidized ferredoxin + H2O R10657 ATP:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phosphotransferase; ATP + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> ADP + 3-O-Phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R10658 S-adenosyl-L-methionine:3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-alpha-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase; S-Adenosyl-L-methionine + 3-O-Phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> S-Adenosyl-L-homocysteine + 3-O-Methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R10659 CTP:phytol O-phosphotransferase; CTP + Phytol <=> CDP + Phytyl phosphate R10660 fumarate CoM:CoB oxidoreductase (succinate forming); Fumarate + Coenzyme M + Coenzyme B <=> Succinate + Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide R10661 L-Tryptophan + L-Proline + 2 ATP <=> Brevianamide F + 2 AMP + 2 Diphosphate R10662 dTDP-beta-L-evernosamine,NADPH:oxygen oxidoreductase (N-hydroxylating); dTDP-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-N-hydroxy-beta-L-evernosamine + NADP+ + H2O R10663 dTDP-beta-L-evernosamine,NADPH:oxygen oxidoreductase (N-hydroxylating); dTDP-N-hydroxy-beta-L-evernosamine + NADPH + H+ + Oxygen <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + 2 H2O R10664 dTDP-beta-L-evernosamine,NADPH:oxygen oxidoreductase (N-hydroxylating); dTDP-beta-L-evernosamine + 2 NADPH + 2 H+ + 2 Oxygen <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 NADP+ + 3 H2O R10665 UDP-2-acetamido-2,6-dideoxy-L-talose:NADP+ oxidoreductase; UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + NADPH + H+ R10666 chorismate hydro-lyase (3-[(1-carboxyvinyl)oxy]benzoate-forming); Chorismate <=> 3-[(1-Carboxyvinyl)oxy]benzoate + H2O R10667 S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming); S-Adenosyl-L-methionine + 3-[(1-Carboxyvinyl)oxy]benzoate + H2O <=> 6-Amino-6-deoxyfutalosine + L-Methionine + HCO3- R10668 6-amino-6-deoxyfutalosine ribohydrolase; 6-Amino-6-deoxyfutalosine + H2O <=> Dehypoxanthine futalosine + Adenine R10669 6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (castasterone-forming); 6-Deoxocastasterone + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> Castasterone + 3 H2O + 2 [Oxidized NADPH---hemoprotein reductase] R10670 phenylacetaldehyde-oxime,NADPH:oxygen oxidoreductase (adding cysteine); (E)-Phenylacetaldoxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O R10671 L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); L-Tyrosine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (E)-4-Hydroxyphenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O + CO2 R10672 4-hydroxyphenylacetaldehyde-oxime,NADPH:oxygen oxidoreductase (adding cysteine); (E)-4-Hydroxyphenylacetaldehyde oxime + L-Cysteine + NADPH + Oxygen + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O R10673 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate L-aspartate-4-semialdehyde-lyase (glycerone-phosphate-forming); 2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> Glycerone phosphate + L-Aspartate 4-semialdehyde R10674 (3R)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming); (3R)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate R10675 L-carnitinyl-CoA hydro-lyase [(E)-4-(trimethylammonio)but-2-enoyl-CoA-forming]; L-Carnitinyl-CoA <=> (E)-4-(Trimethylammonio)but-2-enoyl-CoA + H2O R10676 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase; UDP-2-acetamido-2,6-dideoxy-beta-L-talose <=> UDP-N-acetyl-beta-L-fucosamine R10677 citrate:L-glutamate ligase (ADP-forming); ATP + Citrate + L-Glutamate <=> ADP + Orthophosphate + beta-Citryl-L-glutamate R10678 N-acetyl-L-aspartate:L-glutamate ligase (ADP, N-acetyl-L-aspartyl-L-glutamate-forming); ATP + N-Acetyl-L-aspartate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamate R10679 N-acetyl-L-aspartate:L-glutamate ligase (ADP, N-acetyl-L-aspartyl-L-glutamyl-L-glutamate-forming); 2 ATP + N-Acetyl-L-aspartate + 2 L-Glutamate <=> 2 ADP + 2 Orthophosphate + N-Acetylaspartylglutamylglutamate R10680 S-adenosyl-L-methionine:(+/-)-pavine N-methyltransferase; S-Adenosyl-L-methionine + (+/-)-Pavine <=> S-Adenosyl-L-homocysteine + N-Methylpavine R10681 anthraniloyl-CoA:methanol O-anthraniloyltransferase; Anthraniloyl-CoA + Methanol <=> CoA + O-Methyl anthranilate R10682 6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (brassinolide-forming); 6-Deoxocastasterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Brassinolide + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R10683 6-deoxotyphasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (7-oxatyphasterol-forming); 6-Deoxotyphasterol + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 7-Oxatyphasterol + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R10684 6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (7-oxateasterone-forming); 6-Deoxoteasterone + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> 7-Oxateasterone + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R10685 NAD+:glycine ADP-D-ribosyltransferase (dehydroalanine-producing); NAD+ + Glycine + [Protein]-L-cysteine <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + Nicotinamide + [Protein]-dehydroalanine + 3 H2O R10686 Pyridoxal phosphate + L-Histidine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine R10687 N-Acetylaspartylglutamate + H2O <=> N-Acetyl-L-aspartate + L-Glutamate R10688 N-Acetylaspartylglutamylglutamate + H2O <=> N-Acetylaspartylglutamate + L-Glutamate R10689 L-fucono-1,5-lactone lactonohydrolase; L-Fucono-1,5-lactone + H2O <=> L-Fuconate R10690 2-dehydro-3-deoxy-L-fuconate:NAD+ 4-oxidoreductase; 2-Dehydro-3-deoxy-L-fuconate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+ R10691 2,4-Diketo-3-deoxy-L-fuconate + H2O <=> (S)-Lactate + Pyruvate R10692 20,21-Diprenylterpendole J + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem E + 3 NADP+ + 4 H2O R10693 N-acetyl-L-aspartyl-L-glutamate:L-glutamate ligase (ADP, N-acetyl-L-aspartyl-L-glutamyl-L-glutamate-forming); ATP + N-Acetylaspartylglutamate + L-Glutamate <=> ADP + Orthophosphate + N-Acetylaspartylglutamylglutamate R10694 20,21-Diprenylterpendole C + 3 Oxygen + 3 NADPH + 3 H+ <=> Lolitrem B + 3 NADP+ + 4 H2O R10695 6-amino-6-deoxyfutalosine deaminase; 6-Amino-6-deoxyfutalosine + H2O <=> Futalosine + Ammonia R10696 6-oxocyclohex-1-ene-1-carbonyl-CoA hydro-lyase (2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA-forming); 6-Oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA R10697 styrene-oxide isomerase (epoxide-cleaving); (S)-2-Phenyloxirane <=> Phenylacetaldehyde R10698 kanosamine-6-phosphate:2-oxoglutarate aminotransferase; Kanosamine 6-phosphate + 2-Oxoglutarate <=> 3-Dehydro-D-glucose 6-phosphate + L-Glutamate R10699 L-lysine:8-amino-7-oxononanoate aminotransferase; L-Lysine + 8-Amino-7-oxononanoate <=> L-2-Aminoadipate 6-semialdehyde + 7,8-Diaminononanoate R10700 palmitoyl-[acp]:CoA S-palmitoyltransferase; Hexadecanoyl-[acp] + CoA <=> Palmitoyl-CoA + Acyl-carrier protein R10701 5-O-Caffeoylshikimic acid + H2O <=> Caffeate + Shikimate R10702 propane,NADH:oxygen oxidoreductase (2-hydroxylating); Propane + NADH + H+ + Oxygen <=> Propan-2-ol + NAD+ + H2O R10703 propan-2-ol:NAD+ oxidoreductase; Propan-2-ol + NAD+ <=> Acetone + NADH + H+ R10704 acetone,NADPH:oxygen oxidoreductase (methyl acetate-forming); Acetone + NADPH + H+ + Oxygen <=> Methyl acetate + NADP+ + H2O R10705 methyl acetate acetohydrolase; Methyl acetate + H2O <=> Acetate + Methanol R10706 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase 2'-(5-phosphoribosyl)-3'-dephospho-CoA-transferase; 2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Apo-[acyl-carrier protein] <=> Acyl-carrier protein + Diphosphate R10707 acetyl-CoA:malonyl-[acyl-carrier protein] C-acetyltransferase (decarboxylating); Acetyl-CoA + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CoA + CO2 R10708 geranylgeranyl-diphosphate:homogentisate geranylgeranyltransferase; Geranylgeranyl diphosphate + Homogentisate <=> Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 R10709 S-adenosyl-L-methionine:2-methyl-6-solanyl-1,4-benzoquinol C3-methyltransferase; S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + Plastoquinol-9 R10710 S-adenosyl-L-methionine:6-geranylgeranyl-2-methylbenzene-1,4-diol C3-methyltransferase; S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol <=> S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol R10711 ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O <=> 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate + AMP R10712 2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate 2-methyl-4-aminopyrimidine-5-methenyltransferase; 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate <=> Thiamin monophosphate + Diphosphate + CO2 R10713 primary alcohol:cytochrome cL oxidoreductase; Primary alcohol + 2 Ferricytochrome cL <=> Aldehyde + 2 Ferrocytochrome cL + 2 H+ R10714 cis-Dec-3-enoyl-[acp] <=> n-7 Unsaturated acyl-[acyl-carrier protein] R10715 (S)-Lactaldehyde + NAD+ <=> Methylglyoxal + NADH + H+ R10716 S-adenosyl-L-methionine:rRNA (adenine-N6-)-dimethyltransferase; 2 S-Adenosyl-L-methionine + Adenine in rRNA <=> 2 S-Adenosyl-L-homocysteine + N6-Dimethyladenine in rRNA R10717 propane-1,2-diol:NAD+ 2-oxidoreductase; Propane-1,2-diol + NAD+ <=> Hydroxyacetone + NADH + H+ R10718 hydroxyacetone:NAD+ 1-oxidoreductase; Methylglyoxal + NADH + H+ <=> Hydroxyacetone + NAD+ R10719 (2S)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase; (2S)-2,3-Dihydroxypropane-1-sulfonate + NAD+ <=> (2S)-3-Sulfolactaldehyde + NADH + H+ R10720 3-amino-4-hydroxybenzoate:N-acetyl-L-cysteine:oxygen oxidoreductase; 2 3-Amino-4-hydroxybenzoate + Acetylcysteine + 2 Oxygen <=> Grixazone B + 4 H2O + CO2 R10721 3-methyl-L-tyrosine:hydrogen-peroxide oxidoreductase (3-hydroxy-5-methyl-L-tyrosine-forming); 3-Methyl-L-tyrosine + Hydrogen peroxide <=> 3-Hydroxy-5-methyl-L-tyrosine + H2O R10722 2-amino-1-hydroxyethylphosphonate:oxygen 1-oxidoreductase (glycine-forming); (2-Amino-1-hydroxyethyl)phosphonate + Oxygen <=> Glycine + Orthophosphate R10723 L-isoleucine,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating); L-Isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-4-Hydroxy-L-isoleucine + Succinate + CO2 R10724 (2-aminoethyl)phosphonate,2-oxoglutarate:oxygen oxidoreductase (1-hydroxylating); 2-Aminoethylphosphonate + 2-Oxoglutarate + Oxygen <=> (2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2 R10725 5-methyl-1-naphthoate,NADPH:oxygen oxidoreductase (3-hydroxylating); 5-Methyl-1-naphthoate + NADPH + H+ + Oxygen <=> 3-Hydroxy-5-methyl-1-naphthoate + NADP+ + H2O R10726 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-longipinene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Longipinene + Diphosphate R10727 Miltiradiene <=> Abieta-8,11,13-triene R10728 phylloquinone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxyphylloquinone forming); Phylloquinone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> omega-Hydroxyphylloquinone + [Oxidized NADPH---hemoprotein reductase] + H2O R10729 L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating); L-Phenylalanine + Tetrahydrobiopterin + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin R10730 (R)-2-methylpyrrolidine:NADP+ 2-oxidoreductase; (R)-2-Methylpyrrolidine + NADP+ <=> 2-Methyl-1-pyrroline + NADPH + H+ R10731 (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein],FADH2:oxygen oxidoreductase (5-hydroxylating); (S)-3-Chloro-beta-tyrosyl-[pcp] + FADH2 + Oxygen <=> (S)-3-Chloro-4,5-dihydroxy-beta-phenylalanyl-[pcp] + FAD + H2O R10732 (2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-exo-alpha-bergamotene-forming); trans,trans-Farnesyl diphosphate <=> (-)-exo-alpha-Bergamotene + Diphosphate R10733 (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-alpha-santalene-forming); trans,trans-Farnesyl diphosphate <=> (+)-alpha-Santalene + Diphosphate R10734 (2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-beta-santalene-forming); trans,trans-Farnesyl diphosphate <=> beta-Santalene + Diphosphate R10735 OA-6129-A,2-oxoglutarate:oxygen oxidoreductase (8-hydroxylating); OA-6129 A + 2-Oxoglutarate + Oxygen <=> OA-6129 B2 + Succinate + CO2 R10736 (5R)-Carbapen-2-em-3-carboxylate + L-Cysteine <=> C20817 + CO2 R10737 C20817 <=> C20818 R10738 C20818 <=> C20819 R10739 C20819 <=> 2,3-Dihydrothienamycin R10740 2,3-dihydrothienamycin,2-oxoglutarate:oxygen oxidoreductase (dehydrating); 2,3-Dihydrothienamycin + 2-Oxoglutarate + Oxygen <=> Thienamycin + Succinate + CO2 + H2O R10741 epithienamycin-F,2-oxoglutarate:oxygen oxidoreductase (dehydrating); Epithienamycin F + 2-Oxoglutarate + Oxygen <=> Epithienamycin E + Succinate + CO2 + H2O R10742 epithienamycin-E,2-oxoglutarate:oxygen oxidoreductase (sulfoxidation); Epithienamycin E + 2-Oxoglutarate + Oxygen <=> MM 4550 + Succinate + CO2 R10743 C20819 <=> 8-Dehydroxythienamycin R10744 8-Dehydroxythienamycin <=> Thienamycin R10745 acetyl-CoA:thienamycin N-acetyltransferase; Acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin R10746 acetyl-CoA:deacetyl-MM17880 N-acetyltransferase; Acetyl-CoA + Deacetylepithienamycin F <=> CoA + Epithienamycin F R10747 CoA nucleotidohydrolase; CoA + H2O <=> Pantetheine 4'-phosphate + Adenosine 3',5'-bisphosphate R10748 pantetheine-4'-phosphate phosphohydrolase; Pantetheine 4'-phosphate + H2O <=> Pantetheine + Orthophosphate R10749 C20821 + Pantetheine <=> OA-6129 A R10750 OA-6129 B2 <=> OA-6129 B1 R10751 3'-phosphoadenylyl-sulfate:OA-6129-B1 sulfotransferase; 3'-Phosphoadenylyl sulfate + OA-6129 B1 <=> Adenosine 3',5'-bisphosphate + OA-6129 C R10752 OA-6129-C amidohydrolase; OA-6129 C + H2O <=> Deacetylepithienamycin F + Pantothenate R10753 C20818 <=> C20822 R10754 C20822 <=> C20823 R10755 C20823 <=> C20819 R10756 C20822 <=> Northienamycin R10757 all-trans-polyprenyl-diphosphate:1,4-dihydroxy-2-naphthoate polyprenyltransferase; all-trans-Polyprenyl diphosphate + 1,4-Dihydroxy-2-naphthoate <=> Demethylmenaquinol + Diphosphate + CO2 R10758 4-hydroxybutanoate:CoA ligase (ADP-forming); 4-Hydroxybutanoic acid + ATP + CoA <=> 4-Hydroxybutyryl-CoA + ADP + Orthophosphate R10759 3-Hydroxyisovaleryl-CoA <=> 3-Hydroxyisovalerate R10760 6-deoxy-6-sulfofructose-1-phosphate (2S)-3-sulfolactaldehyde-lyase (glycerone-phosphate-forming); 6-Deoxy-6-sulfo-D-fructose 1-phosphate <=> Glycerone phosphate + (2S)-3-Sulfolactaldehyde R10761 hydroperoxyicosatetraenoate hydro-lyase (oxoicosatetraenoate-forming); Hydroperoxyicosatetraenoate <=> Oxoicosatetraenoate + H2O R10762 all-trans-pentaprenyl-diphosphate diphosphate-lyase (cyclizing, ophiobolin-F-forming); all-trans-Pentaprenyl diphosphate + H2O <=> Ophiobolin F + Diphosphate R10763 geranylgeranyl-diphosphate diphosphate-lyase (cyclooctat-9-en-7-ol-forming); Geranylgeranyl diphosphate + H2O <=> Cyclooctat-9-en-7-ol + Diphosphate R10764 alpha-L-fucopyranose 1-epimerase; alpha-L-Fucopyranose <=> beta-L-Fucopyranose R10765 6-deoxy-6-sulfo-D-glucopyranose aldose-ketose-isomerase; 6-Sulfo-beta-D-quinovose <=> 6-Deoxy-6-sulfo-D-fructose R10766 hydroperoxyicosatetraenoate hydroxymutase; Hydroperoxyicosatetraenoate <=> Hydroxyepoxyicosatrienoate R10767 tobramycin:carbamoyl-phosphate ligase (AMP,phosphate-forming); Tobramycin + Carbamoyl phosphate + ATP + H2O <=> Nebramycin 5' + AMP + Diphosphate + Orthophosphate R10768 kanamycin-A:carbamoyl-phosphate ligase (AMP,phosphate-forming); Kanamycin A + Carbamoyl phosphate + ATP + H2O <=> 6''-O-Carbamoylkanamycin A + AMP + Diphosphate + Orthophosphate R10769 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate:CoA ligase (AMP-forming); ATP + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA <=> AMP + Diphosphate + 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA R10770 (25S)-3-oxocholest-4-en-26-oate:CoA ligase (AMP-forming); ATP + Delta4-Dafachronic acid + CoA <=> AMP + Diphosphate + (25S)-3-Oxocholest-4-en-26-oyl-CoA R10771 2-hydroxy-7-methoxy-5-methyl-1-naphthoate:CoA ligase; ATP + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA <=> AMP + Diphosphate + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA R10772 L-glutamate:aniline ligase (ADP-forming); ATP + L-Glutamate + Aniline <=> ADP + Orthophosphate + N5-Phenyl-L-glutamine R10773 2-Amino-2-deoxy-D-gluconate <=> (2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate + H2O R10774 (2Z,4S,5R)-2-Amino-4,5,6-trihydroxyhex-2-enoate <=> (4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate R10775 (4S,5R)-4,5,6-Trihydroxy-2-iminohexanoate + H2O <=> 2-Dehydro-3-deoxy-D-gluconate + Ammonia R10776 2'-deoxyribonucleoside 5'-monophosphate phosphohydrolase; Deoxynucleoside 5'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate R10777 5-methylbarbiturate amidohydrolase (2-methyl-3-oxo-3-ureidopropanoate-forming); 5-Methylbarbiturate + H2O <=> 3-Oxo-3-ureidoisobutyrate R10778 2-methyl-3-oxo-3-ureidopropanoate amidohydrolase (urea- and methylmalonate-forming); 3-Oxo-3-ureidoisobutyrate + H2O <=> Methylmalonate + Urea R10779 ATP:(R)-mevalonate 3-phosphotransferase; (R)-Mevalonate + ATP <=> (R)-Mevalonate 3-phosphate + ADP R10780 ATP:(R)-3-phosphomevalonate 5-phosphotransferase; (R)-Mevalonate 3-phosphate + ATP <=> (R)-Mevalonate 3,5-bisphosphate + ADP R10781 (R)-3,5-bisphosphomevalonate carboxy-lyase (isopentenyl-phosphate-forming); (R)-Mevalonate 3,5-bisphosphate <=> Isopentenyl phosphate + CO2 + Orthophosphate R10782 4-hydroxybutanoyl-CoA hydro-lyase; 4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O R10783 3-hexenol:NAD+ oxidoreductase; 3-Hexenal + NADH + H+ <=> 3-Hexenol + NAD+ R10784 (2->6)-beta-D-fructanan 6-(beta-D-fructosyl)-D-fructohydrolase; levan levanbiohydrolase; Levan + H2O <=> Levan + Levanbiose R10785 UDP-N-acetyl-alpha-D-glucosamine:NAD+ 3-oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine + NAD+ <=> UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ R10786 (2S)-2-hydroxycarboxylate:NADP+ oxidoreductase; (S)-2-Hydroxyacid + NADP+ <=> 2-Oxo acid + NADPH + H+ R10787 L-arabinose:NADP+ 1-oxidoreductase; L-Arabinose + NADP+ <=> L-Arabinono-1,4-lactone + NADPH + H+ R10788 L-rhamnose:NADP+ 1-oxidoreductase; L-Rhamnose + NADP+ <=> L-Rhamnono-1,4-lactone + NADPH + H+ R10789 L-ornithine,NADPH:oxygen oxidoreductase (N5-hydroxylating); L-Ornithine + NADPH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NADP+ + H2O R10790 L-ornithine,NADH:oxygen oxidoreductase (N5-hydroxylating); L-Ornithine + NADH + H+ + Oxygen <=> N5-Hydroxy-L-ornithine + NAD+ + H2O R10791 dihydromonacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); Dihydromonacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 3alpha-Hydroxy-3,5-dihydromonacolin L acid + [Oxidized NADPH---hemoprotein reductase] + H2O R10792 3alpha-hydroxy-3,5-dihydromonacolin L acid hydro-lyase; 3alpha-Hydroxy-3,5-dihydromonacolin L acid <=> Monacolin L acid + H2O R10793 dihydromonacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); Dihydromonacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin L acid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10794 monacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); Monacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin J acid + [Oxidized NADPH---hemoprotein reductase] + H2O R10795 docosahexaenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (22-hydroxydocosahexaenoate forming); (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22-Hydroxydocosahexaenoate + [Oxidized NADPH---hemoprotein reductase] + H2O R10796 2-hydroxy-5-methyl-1-naphthoate,reduced ferredoxin:oxygen oxidoreductase (7-hydroxylating); 2-Hydroxy-5-methyl-1-naphthoate + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 2,7-Dihydroxy-5-methyl-1-naphthoate + 2 Oxidized ferredoxin + H2O R10797 formate:coenzyme-F420 oxidoreductase; Formate + Coenzyme F420 <=> CO2 + Reduced coenzyme F420 R10798 dihydrosanguinarine:NAD+ oxidoreductase; Dihydrosanguinarine + NAD+ <=> Sanguinarine + NADH + H+ R10799 dihydrosanguinarine:NADP+ oxidoreductase; Dihydrosanguinarine + NADP+ <=> Sanguinarine + NADPH + H+ R10800 dihydrochelirubine:NAD+ oxidoreductase; Dihydrochelirubine + NAD+ <=> Chelirubine + NADH + H+ R10801 dihydrochelirubine:NADP+ oxidoreductase; Dihydrochelirubine + NADP+ <=> Chelirubine + NADPH + H+ R10802 5,6,7,8-tetrahydromethanopterin:acceptor 5,6-oxidoreductase; 5,6,7,8-Tetrahydromethanopterin + Acceptor <=> 7,8-Dihydromethanopterin + Reduced acceptor R10803 hydrogen sulfide:coenzyme F420 oxidoreductase; Hydrogen sulfide + 3 Coenzyme F420 + 3 H2O <=> Sulfite + 3 Reduced coenzyme F420 R10804 UDP-alpha-D-galactose:1-alkyl-2-acylglycerol 3-beta-D-galactosyl-transferase; 1-Alkyl-2-acylglycerol + UDP-alpha-D-galactose <=> Galactosyl-1-alkyl-2-acylglycerol + UDP R10805 3'-phosphoadenylyl-sulfate:1-alkyl-2-acyl-3-beta-galactosyl-sn-glycerol 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Galactosyl-1-alkyl-2-acylglycerol <=> Adenosine 3',5'-bisphosphate + Seminolipid R10806 S-adenosyl-L-methionine:[protein]-L-glutamine (N5-glutamine)-methyltransferase; Protein glutamine + S-Adenosyl-L-methionine <=> Protein N5-methyl-L-glutamine + S-Adenosyl-L-homocysteine R10807 UDP-alpha-D-glucose:diglucosyldiacylglycerol 6-glucosyltransferase; Diglucosyldiacylglycerol + UDP-glucose <=> Triglucosyldiacylglycerol + UDP R10809 alpha-1,6-mannobiose alpha-D-mannohydrolase; Mannobiose + H2O <=> 2 D-Mannose R10810 beta-1,4-mannobiose 2-epimerase; Mannobiose <=> 4-O-beta-D-Mannopyranosyl-D-glucopyranose R10811 1,4-beta-D-mannooligosaccharide:phosphate alpha-D-mannosyltransferase; 1,4-beta-D-Mannooligosaccharide(n) + (n-2) Orthophosphate <=> Mannobiose + (n-2) D-Mannose 1-phosphate R10812 S-adenosyl-L-methionine:5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-ribonucleotide-[mRNA] 2'-O-methyltransferase; S-Adenosyl-L-methionine + m7G(5')pppRm-mRNA <=> S-Adenosyl-L-homocysteine + 5'-(N7-Methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)-[mRNA] R10813 nucleoside-triphosphate:nucleoside-triphosphate nucleotidyltransferase (DNA-directed); n Nucleoside triphosphate <=> 5'-Triphospho-[mRNA](n) + (n-1) Diphosphate R10814 5'-triphospho-[mRNA] phosphohydrolase; 5'-Triphospho-[mRNA] + H2O <=> (5')ppPur-mRNA + Orthophosphate R10815 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] N7-methylguanosine-5'-diphosphate phosphohydrolase; m7G(5')pppR-mRNA + H2O <=> N7-Methylguanosine 5'-diphosphate + 5'-Phospho-[mRNA] R10816 5'-triphospho-[mRNA] diphosphatase; 5'-Triphospho-[mRNA] + H2O <=> 5'-Phospho-[mRNA] + Diphosphate R10817 D-psicose 3-epimerase; D-Psicose <=> D-Fructose R10818 D-tagatose 3-epimerase; D-Tagatose <=> D-Sorbose R10819 L-rhamnopyranose 1-epimerase; alpha-L-Rhamnose <=> beta-L-Rhamnose R10820 3-(methylthio)propanoate:CoA ligase (AMP-forming); ATP + 3-(Methylthio)propanoate + CoA <=> AMP + Diphosphate + 3-(Methylthio)propanoyl-CoA R10821 (R)-pantoate:beta-alanine ligase (ADP-forming); ATP + (R)-Pantoate + beta-Alanine <=> ADP + Orthophosphate + Pantothenate R10822 (deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP); ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m) R10823 (deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP); GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m) R10824 S-adenosyl-L-methionine:3'-hydroxyflavone 3'-O-methyltransferase; S-Adenosyl-L-methionine + 3'-Hydroxyflavone <=> S-Adenosyl-L-homocysteine + 3'-Methoxyflavone R10825 very-long-chain acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating); Very-long-chain acyl-CoA + Malonyl-CoA <=> Very-long-chain 3-oxoacyl-CoA + CO2 + CoA R10826 very-long-chain-(3R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase; Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+ R10827 very-long-chain (3R)-3-hydroxyacyl-CoA hydro-lyase; Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O R10828 very-long-chain acyl-CoA:NADP+ oxidoreductase; Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ R10829 4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine:phosphate alpha-D-mannosyltransferase; beta-D-Mannosyl-1,4-N-acetyl-D-glucosamine + Orthophosphate <=> N-Acetyl-D-glucosamine + D-Mannose 1-phosphate R10830 beta-D-glucuronoside glucuronosohydrolase; G00526 + H2O <=> G00711 + D-Glucuronate R10831 G00711 + H2O <=> G10008 + N-Acetyl-D-glucosamine R10832 4-O-beta-D-glucopyranosyl-D-gluconate:phosphate alpha-D-glucosyltransferase; Cellobionate + Orthophosphate <=> D-Glucose 1-phosphate + D-Gluconic acid R10833 dTDP-beta-L-vancomycin:desvancosaminyl-vancomycin beta-L-vancosaminetransferase; dTDP-L-vancosamine + Desvancosaminyl-vancomycin <=> dTDP + Vancomycin R10834 UDP-alpha-D-glucose:7-deoxyloganetate O-D-glucosyltransferase; UDP-glucose + 7-Deoxyloganetate <=> UDP + 7-Deoxyloganate R10835 UDP-alpha-D-glucose:7-deoxyloganetin O-D-glucosyltransferase; UDP-glucose + 7-Deoxyloganetin <=> UDP + Deoxyloganin R10836 AMP:phosphate (5-phospho-alpha-D-ribosyl)transferase; AMP + Orthophosphate <=> Adenine + D-Ribose 1,5-bisphosphate R10837 CMP:phosphate (5-phospho-alpha-D-ribosyl)transferase; CMP + Orthophosphate <=> Cytosine + D-Ribose 1,5-bisphosphate R10838 UMP:phosphate (5-phospho-alpha-D-ribosyl)transferase; UMP + Orthophosphate <=> Uracil + D-Ribose 1,5-bisphosphate R10839 O-acetyl-L-serine:isoxazolin-5-one 2-(2-amino-2-carboxyethyl)transferase; O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-2-yl)-L-alanine + Acetate R10840 O-acetyl-L-serine:isoxazolin-5-one 4-(2-amino-2-carboxyethyl)transferase; O-Acetyl-L-serine + Isoxazolin-5-one <=> 3-(5-Oxoisoxazolin-4-yl)-L-alanine + Acetate R10841 D-galacturonate:NAD+ 1-oxidoreductase; D-Galacturonate + NAD+ <=> D-Galactaro-1,5-lactone + NADH + H+ R10842 D-glucuronate:NAD+ 1-oxidoreductase; D-Glucuronate + NAD+ <=> D-Glucaro-1,5-lactone + NADH + H+ R10843 zeaxanthin:oxygen oxidoreductase (7,8-cleaving); Zeaxanthin + Oxygen <=> beta-Citraurin + (3S)-3-Hydroxycyclocitral R10844 beta-citraurin:oxygen oxidoreductase (7,8-cleaving); beta-Citraurin + Oxygen <=> Crocetin dialdehyde + (3S)-3-Hydroxycyclocitral R10845 (2S,3S)-3-methylphenylalanine:2-oxoglutarate aminotransferase; (2S,3S)-3-Methylphenylalanine + 2-Oxoglutarate <=> (3S)-2-Oxo-3-phenylbutanoate + L-Glutamate R10846 D-galactarolactone 4,5-acylmutase; D-Galactaro-1,5-lactone <=> D-Galactaro-1,4-lactone R10847 D-galactaro-1,4-lactone lyase (ring-opening); D-Galactaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate R10848 L-gulonate:NAD+ 5-oxidoreductase; L-Gulonate + NAD+ <=> D-Fructuronate + NADH + H+ R10849 phosphatidylglycerol:Glc-alpha1->2Glc-alpha1->3acyl2Gro glycerophosphotransferase; Phosphatidylglycerol + alpha-Kojibiosyldiacylglycerol <=> 1,2-Diacyl-sn-glycerol + Glycerophosphoglycoglycerolipid R10850 UDP-alpha-D-glucose:1,2-diacyl-sn-glycerol 3-alpha-D-glucosyltransferase; UDP-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol R10851 L-allo-threonine:NADP+ 3-oxidoreductase; L-Allothreonine + NADP+ <=> L-2-Amino-3-oxobutanoic acid + NADPH + H+ R10852 L-allo-threonine:NADP+ 3-oxidoreductase (decarboxylating); L-Allothreonine + NADP+ <=> Aminoacetone + CO2 + NADPH + H+ R10853 5-Hydroxymethyl-2-furaldehyde + Oxygen <=> Furan-2,5-dicarbaldehyde + Hydrogen peroxide R10854 Furan-2,5-dicarbaldehyde + H2O <=> 5-(Dihydroxymethyl)furan-2-carbaldehyde R10855 5-(Dihydroxymethyl)furan-2-carbaldehyde + Oxygen <=> 5-Formyl-2-furoate + Hydrogen peroxide R10856 5-Formyl-2-furoate + H2O <=> 5-(Dihydroxymethyl)furan-2-carboxylate R10857 5-(Dihydroxymethyl)furan-2-carboxylate + Oxygen <=> 2,5-Furandicarboxylate + Hydrogen peroxide R10858 5-(hydroxymethyl)furfural:oxygen oxidoreductase; 5-Hydroxymethyl-2-furaldehyde + 3 Oxygen + 2 H2O <=> 2,5-Furandicarboxylate + 3 Hydrogen peroxide R10859 (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized flavodoxin oxidoreductase; 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + H2O + Oxidized flavodoxin <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + Reduced flavodoxin R10860 D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase; D-Glyceraldehyde 3-phosphate + NAD+ + H2O <=> 3-Phospho-D-glycerate + NADH + H+ R10861 3,6-anhydro-alpha-L-galactopyranose:NAD+ 1-oxidoredutase; 3,6-Anhydro-alpha-L-galactopyranose + NAD+ + H2O <=> 3,6-Anhydro-L-galactonate + NADH + H+ R10862 3,6-anhydro-alpha-L-galactopyranose:NADP+ 1-oxidoredutase; 3,6-Anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-Anhydro-L-galactonate + NADPH + H+ R10863 Glycerophosphoglycoglycerolipid <=> Lipoteichoic acid R10864 Glycerophosphoglycoglycerolipid <=> Lipoteichoic acid R10865 UDP-galactose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) galactosyltransferase; UDP-alpha-D-galactose + 1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol <=> UDP + Galactosylglucosyldiacylglycerol R10866 pyruvate:flavodoxin 2-oxidoreductase (CoA-acetylating); Pyruvate + CoA + Oxidized flavodoxin <=> Acetyl-CoA + CO2 + Reduced flavodoxin R10867 beta-D-4-deoxy-Delta4-GlcAp-(1->3)-D-GalNAc6S hydrolase; 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 5-Dehydro-4-deoxy-D-glucuronate + N-Acetyl-D-galactosamine 6-sulfate R10868 3'-phospho-5'-adenylyl sulfate:[dermatan]-4-O-sulfo-N-acetyl-D-galactosamine 6-O-sulfotransferase; 3'-Phosphoadenylyl sulfate + Dermatan 4-sulfate <=> Adenosine 3',5'-bisphosphate + Dermatan 4,6-sulfate R10869 3'-phospho-5'-adenylyl sulfate:[chondroitin]-4-O-sulfo-N-acetyl-D-galactosamine 6-O-sulfotransferase; 3'-Phosphoadenylyl sulfate + Chondroitin 4-sulfate <=> Adenosine 3',5'-bisphosphate + Chondroitin 4,6-sulfate R10870 chondroitin-sulfate-A lyase; Chondroitin 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate R10871 dermatan-sulfate lyase; chondroitin-sulfate-B lyase; Dermatan 4-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate R10872 chondroitin-sulfate-C lyase; Chondroitin 6-sulfate <=> n 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate R10873 3'-phospho-5'-adenylyl sulfate:[dermatan]-N-acetyl-D-galactosamine 4-sulfotransferase; 3'-Phosphoadenylyl sulfate + Dermatan <=> Adenosine 3',5'-bisphosphate + Dermatan 4-sulfate R10874 dTDP-6-deoxy-alpha-D-allose:mycinamicin-VII 21-O-6-deoxy-beta-D-allosyltransferase; dTDP-6-deoxy-D-allose + Mycinamicin VII <=> Mycinamicin VI + dTDP R10875 mycinamicin-VIII,NADPH:oxygen oxidoreductase (21-hydroxylating); Mycinamicin VIII + NADPH + Oxygen + H+ <=> Mycinamicin VII + NADP+ + H2O R10876 dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:protomycinolide-IV 5-O-(3-dimethylamino-3,4,6-trideoxy-beta-D-glucosyl)transferase; dTDP-D-desosamine:protomycinolide-IV 5-O-beta-D-desosaminyltransferase; dTDP-D-desosamine + Protomycinolide IV <=> Mycinamicin VIII + dTDP R10877 mycinamicin-IV,NADPH:oxygen oxidoreductase (14-hydroxylating); Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin V + NADP+ + H2O R10878 mycinamicin-V,NADPH:oxygen oxidoreductase (12,13-epoxidizing); Mycinamicin V + NADPH + Oxygen + H+ <=> Mycinamicin II + NADP+ + H2O R10879 mycinamicin-IV,NADPH:oxygen oxidoreductase (12,13-epoxidizing); Mycinamicin IV + NADPH + Oxygen + H+ <=> Mycinamicin I + NADP+ + H2O R10880 5 ATP + 3 L-4-Hydroxyphenylglycine + L-Arginine + L-Serine + H2O <=> 5 AMP + 5 Diphosphate + Nocardicin G + L-4-Hydroxyphenylglycyl-L-arginine R10881 S-adenosyl-L-methionine:nocardicin-G 3-amino-3-carboxypropyltransferase; S-Adenosyl-L-methionine + Nocardicin G <=> 5'-Methylthioadenosine + Isonocardicin C R10882 nocardicin-C,NADPH:oxygen oxidoreductase; Nocardicin C + 2 NADPH + 2 H+ + 2 Oxygen <=> Nocardicin A + 2 NADP+ + 3 H2O R10883 nocardicin-C epimerase; Isonocardicin C <=> Nocardicin C R10884 N-Acetyl-L-2-amino-6-oxopimelate <=> C20911 R10885 C20911 <=> C20912 R10886 C20912 <=> C20913 R10887 C20913 <=> C20914 + CO2 R10888 C20914 + L-Threonine <=> C20915 R10889 C20915 <=> C20916 R10890 C20916 <=> Tabtoxin R10891 Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-Threonine R10892 tabtoxinine-beta-lactam:L-threonine ligase (ADP-forming); ATP + Tabtoxinine-beta-lactam + L-Threonine <=> ADP + Orthophosphate + Tabtoxin R10893 acetyl-CoA:tabtoxinine-beta-lactam N-acetyltransferase; Acetyl-CoA + Tabtoxinine-beta-lactam <=> CoA + N1-Acetyl-tabtoxinine-beta-lactam R10894 Tabtoxinine-beta-lactam <=> Tabtoxinine-delta-lactam R10895 Tabtoxin <=> Isotabtoxin R10896 geranylgeranyl-diphosphate diphosphate-lyase (cembrene-C-forming); Geranylgeranyl diphosphate <=> Cembrene C + Diphosphate R10897 geranylgeranyl-diphosphate diphosphate-lyase [(R)-nephthenol-forming]; Geranylgeranyl diphosphate + H2O <=> (R)-Nephthenol + Diphosphate R10898 geranylgeranyl-diphosphate diphosphate-lyase [(R)-cembrene-A-forming]; Geranylgeranyl diphosphate <=> Neocembrene + Diphosphate R10899 geranylgeranyl-diphosphate diphosphate-lyase [(1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol-forming]; Geranylgeranyl diphosphate + H2O <=> (1S,4E,8E,12E)-2,2,5,9,13-Pentamethylcyclopentadeca-4,8,12-trien-1-ol + Diphosphate R10900 3,6-anhydro-L-galactonate lyase (ring-opening); 3,6-Anhydro-L-galactonate <=> 2-Dehydro-3-deoxy-L-galactonate R10901 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase; ATP + UDP-N-acetylmuramate + L-Alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate R10902 tyramine:L-glutamate gamma-ligase (ADP-forming); ATP + Tyramine + L-Glutamate <=> ADP + Orthophosphate + gamma-Glutamyltyramine R10903 Nocardicin G <=> Nocardicin E R10904 succinyl-CoA:mesaconate CoA-transferase; Succinyl-CoA + Mesaconate <=> Succinate + 2-Methylfumaryl-CoA R10905 Hyaluronic acid + H2O <=> Hyaluronic acid + G00526 R10906 (9Z)-hexadec-9-enoyl-[acyl-carrier protein]:KDO2-lipid IVA O-palmitoleoyltransferase; Hexadecenoyl-[acyl-carrier protein] + KDO2-lipid IVA <=> (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) + Acyl-carrier protein R10907 beta-D-glucose-6-phosphate:NAD+ 1-oxidoreductase; beta-D-Glucose 6-phosphate + NAD+ <=> D-Glucono-1,5-lactone 6-phosphate + NADH + H+ R10908 (S)-ureidoglycine:glyoxylate aminotransferase; (S)-Ureidoglycine + Glyoxylate <=> Glycine + Oxalureate R10909 ATP:ATP adenylyltransferase (2'-5' linkages-forming); 3 ATP <=> pppA2'p5'A2'p5'A + 2 Diphosphate R10910 ATP:ATP adenylyltransferase (2'-5' linkages-forming); n ATP <=> 2-5A + (n-1) Diphosphate R10911 aldehyde:quinone oxidoreductase; Aldehyde + Quinone + H2O <=> Carboxylate + Hydroquinone R10912 aldehyde:quinone oxidoreductase; Aldehyde + Quinone + H2O <=> Fatty acid + Hydroquinone R10913 Hydroxylamine + 2 Ferricytochrome c <=> Nitroxyl + 2 Ferrocytochrome c + 2 H+ R10914 Nitroxyl + 2 Ferrocytochrome c + Oxygen + H+ <=> Nitrite + 2 Ferricytochrome c + H2O R10915 reactive-blue-5:hydrogen-peroxide oxidoreductase; Reactive Blue 5 + 2 Hydrogen peroxide <=> Phthalate + 2,2'-Disulfonyl azobenzene + 3-[(4-Amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O R10916 (2R)-2,3-dihydroxy-3-methylbutanoate:NAD+ oxidoreductase (isomerizing); (R)-2,3-Dihydroxy-3-methylbutanoate + NAD+ <=> (S)-2-Acetolactate + NADH + H+ R10917 L-dihydroanticapsin:NAD+ oxidoreductase; L-Dihydroanticapsin + NAD+ <=> L-Anticapsin + NADH + H+ R10918 (R)-ipsdienol:NAD+ oxidoreductase; (R)-Ipsdienol + NAD+ <=> Ipsdienone + NADH + H+ R10919 (R)-ipsdienol:NADP+ oxidoreductase; (R)-Ipsdienol + NADP+ <=> Ipsdienone + NADPH + H+ R10920 xanthine,2-oxoglutarate:oxygen oxidoreductase; Xanthine + 2-Oxoglutarate + Oxygen <=> Urate + Succinate + CO2 R10921 beta-Amyrin + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Erythrodiol + [Oxidized NADPH---hemoprotein reductase] + H2O R10922 Erythrodiol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R10923 Oleanolic aldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Oleanolic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R10924 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (28-hydroxylating); beta-Amyrin + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Oleanolic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R10925 (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Farnesoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Juvenile hormone III acid + [Oxidized NADPH---hemoprotein reductase] + H2O R10926 icosanoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating); Eicosanoyl-CoA + Ferrocytochrome b5 + Oxygen + 2 H+ <=> (Z)-Icos-5-enoyl-CoA + Ferricytochrome b5 + 2 H2O R10927 arsenate:thioredoxin oxidoreductase; Arsenate ion + Thioredoxin <=> Arsenite + Thioredoxin disulfide + H2O R10928 1-phosphatidyl-1D-myo-inositol-3,5-bisphosphate 3-phosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate R10929 LysW:L-glutamate ligase (ADP-forming); L-Glutamate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-L-glutamate + ADP + Orthophosphate R10930 ATP:LysW-L-glutamate 5-phosphotransferase; LysW-L-glutamate + ATP <=> LysW-L-glutamyl 5-phosphate + ADP R10931 LysW-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating); LysW-L-glutamyl 5-phosphate + NADPH + H+ <=> LysW-L-glutamate 5-semialdehyde + NADP+ + Orthophosphate R10932 LysW-L-ornithine:2-oxoglutarate 5-aminotransferase; LysW-L-glutamate 5-semialdehyde + L-Glutamate <=> LysW-L-ornithine + 2-Oxoglutarate R10933 LysW-L-ornithine amidohydrolase; LysW-L-ornithine + H2O <=> L-Ornithine + alpha-Aminoadipate carrier protein LysW R10934 prephenate carboxy-lyase (3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate-forming); Prephenate <=> 3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2 R10935 (5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O <=> 2 D-Glyceraldehyde 3-phosphate R10936 3-(methylthio)acryloyl-CoA hydratase; 3-(Methylthio)acryloyl-CoA + 2 H2O <=> Acetaldehyde + Methanethiol + CoA + CO2 R10937 alpha-D-sedoheptulopyranose-7-phosphate phosphate-lyase (cyclizing, 2-epi-5-epi-valiolone-forming); alpha-D-Sedoheptulopyranose 7-phosphate <=> 2-epi-5-epi-Valiolone + Orthophosphate R10938 L-alanyl-D-glutamate epimerase; L-Alanyl-D-glutamate <=> L-Alanyl-L-glutamate R10939 (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione aldose-ketose-isomerase; (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione R10940 fumarate:L-2,3-diaminopropanoate ligase (AMP-forming); ATP + Fumarate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + N3-Fumaroyl-L-2,3-diaminopropanoate R10941 N(beta)-epoxysuccinamoyl-DAP:L-valine ligase (ADP-forming); ATP + N(beta)-Epoxysuccinamoyl-DAP + L-Valine <=> ADP + Orthophosphate + N(beta)-Epoxysuccinamoyl-DAP-Val R10942 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-valine ligase (ADP-forming); ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Valine <=> ADP + Orthophosphate + Dapdiamide A R10943 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-isoleucine ligase (ADP-forming); ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Isoleucine <=> ADP + Orthophosphate + Dapdiamide B R10944 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-leucine ligase (ADP-forming); ATP + 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Leucine <=> ADP + Orthophosphate + Dapdiamide C R10945 3-(methylthio)acryloyl-CoA hydratase; 3-hydroxy-3-(methylthio)propanoyl-CoA hydro-lyase; 3-(Methylthio)acryloyl-CoA + H2O <=> 3-Hydroxy-3-(methylthio)propanoyl-CoA R10946 3-hydroxy-3-(methylthio)propanoyl-CoA methanethiol-lyase; 3-Hydroxy-3-(methylthio)propanoyl-CoA <=> 3-Oxopropionyl-CoA + Methanethiol R10947 3-oxopropionyl-CoA hydrolase; 3-Oxopropionyl-CoA + H2O <=> 3-Oxopropanoate + CoA R10948 ATP:HCO3- phosphotransferase; ATP + HCO3- <=> ADP + Carboxyphosphate R10949 Ammonia + Carboxyphosphate <=> Carbamate + Orthophosphate R10950 1D-myo-inositol 1,3,4-trisphosphate 4-phosphohydrolase; 1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 1,3-bisphosphate + Orthophosphate R10951 ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate R10952 1-phosphatidyl-1D-myo-inositol-4-phosphate inositolbisphosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol R10953 ATP:1D-myo-inositol-1,3,4,5-tetrakisphosphate 6-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate R10954 tetracenomycin-B2,NADPH:oxygen oxidoreductase (8-demethyltetracenomycin-C-forming); Tetracenomycin B2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> 8-Demethyltetracenomycin C + 2 NADP+ + 2 H2O R10955 dTDP-beta-L-rhamnose:8-demethyltetracenomycin-C alpha-L-rhamnosyltransferase; dTDP-L-rhamnose + 8-Demethyltetracenomycin C <=> dTDP + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C R10956 S-adenosyl-L-methionine:8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase; S-Adenosyl-L-methionine + 8-Demethyl-8-alpha-L-rhamnosyltetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C R10957 S-adenosyl-L-methionine:8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase; S-Adenosyl-L-methionine + 8-Demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C R10958 S-adenosyl-L-methionine:8-demethyl-8-(2,3-di-O-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase; S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C R10959 S-adenosyl-L-methionine:8-demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin-C O-methyltransferase; S-Adenosyl-L-methionine + 8-Demethyl-8-(2,3,4-tri-O-methyl-alpha-L-rhamnosyl)tetracenomycin C <=> S-Adenosyl-L-homocysteine + Elloramycin A R10960 malonyl-CoA:acetate malonyltransferase (tetracenomycin-F2-forming); 10 Malonyl-CoA <=> Tetracenomycin F2 + 10 CoA + 10 CO2 + 2 H2O R10961 Benzoyl-CoA + Reduced acceptor <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Acceptor R10962 S-adenosyl-L-methionine:3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase; S-Adenosyl-L-methionine + 3-Hydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 3-Methoxy-5-methyl-1-naphthoate R10963 S-adenosyl-L-methionine:2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase; S-Adenosyl-L-methionine + 2,7-Dihydroxy-5-methyl-1-naphthoate <=> S-Adenosyl-L-homocysteine + 2-Hydroxy-7-methoxy-5-methyl-1-naphthoate R10964 S-adenosyl-L-methionine:L-tyrosine C3-methyltransferase; S-Adenosyl-L-methionine + L-Tyrosine <=> S-Adenosyl-L-homocysteine + 3-Methyl-L-tyrosine R10965 malonyl-CoA C-acyl transferase (1,3,6,8-tetrahydroxynaphthalene forming); 5 Malonyl-CoA <=> 1,3,6,8-Naphthalenetetrol + 5 CoA + 5 CO2 + H2O R10966 dimethylallyl-diphosphate:5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase; Dimethylallyl diphosphate + 5,10-Dihydrophenazine-1-carboxylate <=> Diphosphate + 9-(Dimethylallyl)-5,10-dihydrophenazine-1-carboxylate R10967 malonyl-CoA:malonyl-CoA malonyltransferase (decarboxylating, phloroglucinol-forming); 3 Malonyl-CoA <=> Phloroglucinol + 3 CoA + 3 CO2 R10968 dimethylallyl-diphosphate:L-tyrosine 4-O-dimethylallyltransferase; Dimethylallyl diphosphate + L-Tyrosine <=> Diphosphate + 4-O-Dimethylallyl-L-tyrosine R10969 geranyl-diphosphate:flaviolin 3-linalyltransferase; Geranyl diphosphate + Flaviolin <=> 3-Linalylflaviolin + Diphosphate R10970 ATP:6-deoxy-6-sulfo-D-fructose 1-phosphotransferase; ATP + 6-Deoxy-6-sulfo-D-fructose <=> ADP + 6-Deoxy-6-sulfo-D-fructose 1-phosphate R10971 3'-phosphoadenylyl-sulfate:alpha,alpha-trehalose 2-sulfotransferase; 3'-Phosphoadenylyl sulfate + alpha,alpha-Trehalose <=> Adenosine 3',5'-bisphosphate + 2-Sulfotrehalose R10972 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase (D-ribose 2,5-bisphosphate-forming); alpha-D-Ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> D-Ribose 2,5-bisphosphate R10973 D-ribose-2,5-bisphosphate 2-phosphohydrolase; D-Ribose 2,5-bisphosphate + H2O <=> D-Ribose 5-phosphate + Orthophosphate R10974 3-sulfinopropanoyl-CoA sulfinohydrolase; 3-Sulfinopropanoyl-CoA + H2O <=> Propanoyl-CoA + Sulfite R10975 6-aminohexanoate-oligomer exoamidohydrolase; [N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-1) + 6-Aminohexanoate R10976 6-aminohexanoate-oligomer endoamidohydrolase; [N-(6-Aminohexanoyl)]n(n) + H2O <=> [N-(6-Aminohexanoyl)]n(n-x) + [N-(6-Aminohexanoyl)]n(x) R10978 6-aminohexanoate-cyclic-oligomer amidohydrolase; 6-Aminohexanoate cyclic oligomer + H2O <=> [N-(6-Aminohexanoyl)]n R10979 [N-(6-Aminohexanoyl)]n <=> N-(6-Aminohexanoyl)-6-aminohexanoate R10980 5-valerolactone lactonohydrolase; 5-Valerolactone + H2O <=> 5-Hydroxypentanoate R10981 5-hydroxypentanoate:NAD+ oxidoreductase; 5-Hydroxypentanoate + NAD+ <=> 5-Oxopentanoate + NADH + H+ R10982 glutarate-semialdehyde:NADP+ oxidoreductase; 5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+ R10983 methyl-(2E,6E,10R,11S)-10,11-epoxy-7-ethyl-3,11-dimethyl-2,6-tridecadienoate acylhydrolase; Juvenile hormone I + H2O <=> Juvenile hormone I acid + Methanol R10984 L-serine:NADP+ 3-oxidoreductase; L-Serine + NADP+ <=> Aminoacetaldehyde + CO2 + NADPH + H+ R10985 L-Serine + NAD+ <=> 2-Aminomalonate semialdehyde + NADH + H+ R10986 L-serine:NAD+ 3-oxidoreductase; L-Serine + NAD+ <=> Aminoacetaldehyde + CO2 + NADH + H+ R10987 sucrose-6F-phosphate:phosphate 1-alpha-D-glucosyltransferase; Sucrose 6'-phosphate + Orthophosphate <=> D-Glucose 1-phosphate + beta-D-Fructose 6-phosphate R10988 UDP-alpha-D-glucose:beta-D-glucosyl-crocetin beta-1,6-glucosyltransferase; UDP-glucose + beta-D-Glucosyl crocetin <=> UDP + beta-D-Gentiobiosyl crocetin R10989 UDP-alpha-D-glucose:bis(beta-D-glucosyl)-crocetin beta-1,6-glucosyltransferase; UDP-glucose + Bis(beta-D-glucosyl) crocetin <=> UDP + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester R10990 UDP-alpha-D-glucose:beta-D-gentiobiosyl-beta-D-glucosyl-crocetin beta-1,6-glucosyltransferase; UDP-glucose + trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester <=> UDP + Crocin R10991 2-aminobutanoate:2-oxoglutarate aminotransferase; (S)-2-Aminobutanoate + 2-Oxoglutarate <=> 2-Oxobutanoate + L-Glutamate R10992 L-alanine:2-oxobutanoate aminotransferase; L-Alanine + 2-Oxobutanoate <=> Pyruvate + (S)-2-Aminobutanoate R10993 L-glutamate:2-aminobutanoate gamma-ligase (ADP-forming); ATP + L-Glutamate + (S)-2-Aminobutanoate <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-2-aminobutyrate R10994 gamma-L-glutamyl-L-2-aminobutyrate:glycine ligase (ADP-forming); ATP + gamma-L-Glutamyl-L-2-aminobutyrate + Glycine <=> ADP + Orthophosphate + Ophthalmate R10995 L-rhamnose:NAD+ 1-oxidoreductase; L-Rhamnose + NAD+ <=> L-Rhamnono-1,4-lactone + NADH + H+ R10996 2-Oxobutanoate + Thiamin diphosphate <=> 2-(alpha-Hydroxypropyl)thiamine diphosphate + CO2 R10997 2-(alpha-Hydroxypropyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> Enzyme N6-(S-propyldihydrolipoyl)lysine + Thiamin diphosphate R10998 propanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-propanoyltransferase; Propanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + Enzyme N6-(S-propyldihydrolipoyl)lysine R10999 oleoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); Oleoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleoyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O R11000 linoleoyl-CoA,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); Linoleoyl-CoA + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxylinoleoyl-CoA + [Oxidized NADPH---hemoprotein reductase] + H2O R11001 (4R)-4-hydroxysphinganine ceramide,ferrocytochrome-b5:oxygen oxidoreductase (fatty acyl 2-hydroxylating); Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (2'R)-2'-Hydroxyphytoceramide + 2 Ferricytochrome b5 + H2O R11002 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,ferrocytochrome-b5:oxygen oxidoreductase (12-hydroxylating); 1-Acyl-2-oleoyl-sn-glycero-3-phosphocholine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-Acyl-2-[(12R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Ferricytochrome b5 + H2O R11003 dihydroceramide,ferrocytochrome-b5:oxygen oxidoreductase (fatty acyl 2-hydroxylating); Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (2'R)-2'-Hydroxydihydroceramide + 2 Ferricytochrome b5 + H2O R11004 (11Z)-hexadec-11-enoyl-CoA,reduced acceptor:oxygen 10,13-allylic oxidase (10E,12E-forming); (11Z)-Hexadec-11-enoyl-CoA + Reduced acceptor + Oxygen <=> (10E,12Z)-Hexadeca-10,12-dienoyl-CoA + Acceptor + 2 H2O R11005 (4E)-sphing-4-enine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-trans dehydrogenating); N-Acylsphingosine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4E,8E)-Sphinga-4,8-dienine ceramide + 2 Ferricytochrome b5 + 2 H2O R11006 (4E,8E)-sphinga-4,8-dienine ceramide,ferrocytochrome b5:oxygen oxidoreductase (10,11-trans-dehydrogenating); (4E,8E)-Sphinga-4,8-dienine ceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4E,8E,10E)-Sphinga-4,8,10-trienine ceramide + 2 Ferricytochrome b5 + 2 H2O R11007 cholesterol,NADH:oxygen oxidoreductase (7,8 dehydrogenating); Cholesterol + Oxygen + NADH + H+ <=> 7-Dehydrocholesterol + NAD+ + 2 H2O R11008 cholesterol,NADPH:oxygen oxidoreductase (7,8 dehydrogenating); Cholesterol + Oxygen + NADPH + H+ <=> 7-Dehydrocholesterol + NADP+ + 2 H2O R11009 (4R)-4-hydroxysphinganine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-trans-dehydrogenating); Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4R,8E)-4-Hydroxysphing-8-enine ceramide + 2 Ferricytochrome b5 + 2 H2O R11010 (4R)-4-hydroxysphinganine ceramide,ferrocytochrome b5:oxygen oxidoreductase (8,9-cis-dehydrogenating); Phytoceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (4R,8Z)-4-Hydroxysphing-8-enine ceramide + 2 Ferricytochrome b5 + 2 H2O R11011 palmitoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (14,15-trans-dehydrogenating); Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (14E)-Hexadec-14-enoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11012 palmitoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (14,15-cis-dehydrogenating); Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (14Z)-Hexadec-14-enoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11013 hercynine,gamma-L-glutamyl-L-cysteine:oxygen oxidoreductase [gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide-forming]; Hercynine + gamma-L-Glutamyl-L-cysteine + Oxygen <=> gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O R11014 hercynine,L-cysteine:oxygen [S-(hercyn-2-yl)-L-cysteine S-oxide-forming]; Hercynine + L-Cysteine + Oxygen <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O R11015 L-histidine,L-cysteine:oxygen [S-(L-histidin-5-yl)-L-cysteine S-oxide-forming]; L-Histidine + L-Cysteine + Oxygen <=> S-(L-Histidin-5-yl)-L-cysteine S-oxide + H2O R11016 D-Arginine + Acceptor <=> Iminoarginine + Reduced acceptor R11017 Iminoarginine + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia R11018 D-arginine:acceptor oxidoreductase (deaminating); D-Arginine + Acceptor + H2O <=> 5-Guanidino-2-oxopentanoate + Ammonia + Reduced acceptor R11019 5,6,7,8-tetrahydromonapterin:NADP+ oxidoreductase; 5,6,7,8-Tetrahydromonapterin + NADP+ <=> 7,8-Dihydromonapterin + NADPH + H+ R11020 S-adenosyl-L-methionine:dTDP-4-oxo-6-deoxy-D-allose 5-C-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-oxo-6-deoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose R11021 S-gamma-glutamyl hercynylcysteine S-oxide amidohydrolase; gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O <=> S-(Hercyn-2-yl)-L-cysteine S-oxide + L-Glutamate R11022 2-Aminomuconate semialdehyde <=> Picolinic acid + H2O R11023 S-(hercyn-2-yl)-L-cysteine-S-oxide ergothioneine-lyase (deaminating; pyruvate-forming); S-(Hercyn-2-yl)-L-cysteine S-oxide + Reduced acceptor <=> Ergothioneine + Pyruvate + Ammonia + Acceptor R11024 ATP:N-acetyl-D-muramate 1-phosphotransferase; N-Acetylmuramate + ATP <=> N-Acetylmuramic acid alpha-1-phosphate + ADP R11025 UTP:N-acetyl-alpha-D-muramate-1-phosphate uridylyltransferase; N-Acetylmuramic acid alpha-1-phosphate + UTP <=> UDP-N-acetylmuramate + Diphosphate R11026 (R)-5,6-dihydrothymine:NAD+ oxidoreductase; (R)-5,6-Dihydrothymine + NAD+ <=> Thymine + NADH + H+ R11028 (S)-Methylmalonate semialdehyde <=> (R)-Methylmalonate semialdehyde R11029 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate <=> 5-Hydroxymethylcytosine in DNA R11030 5-methylcytosine in DNA,2-oxoglutarate:oxygen oxidoreductase; 5-Methylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Hydroxymethylcytosine in DNA + Succinate + CO2 R11031 L-arginine:NAD+ oxidoreductase (deaminating); 5-Guanidino-2-oxopentanoate + NADH + H+ + Ammonia <=> L-Arginine + NAD+ + H2O R11032 L-arginine:NADP+ oxidoreductase (deaminating); 5-Guanidino-2-oxopentanoate + NADPH + H+ + Ammonia <=> L-Arginine + NADP+ + H2O R11033 L-Arginine <=> N(omega)-Hydroxyarginine R11034 dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> dTDP-3,4-dioxo-2,6-dideoxy-D-glucose R11035 2-dehydro-3-deoxy-L-galactonate:NAD+ 5-oxidoreductase; 2-Dehydro-3-deoxy-L-galactonate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+ R11036 6-deoxy-6-sulfo-D-glucopyranose:NAD+ 1-oxidoreductase; Sulfoquinovose + NAD+ <=> 6-Deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H+ R11037 7,8-dihydroneopterin:oxygen oxidoreductase; 7,8-Dihydroneopterin + Oxygen <=> 7,8-Dihydroxanthopterin + Formate + Glycolaldehyde R11038 L-alanine:(5-formylfuran-3-yl)methyl-phosphate aminotransferase; (5-Formylfuran-3-yl)methyl phosphate + L-Alanine <=> [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate R11039 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase; [5-(Aminomethyl)furan-3-yl]methyl phosphate + ATP <=> [5-(Aminomethyl)furan-3-yl]methyl diphosphate + ADP R11040 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase; [5-(Aminomethyl)furan-3-yl]methyl diphosphate + gamma-Glutamyltyramine <=> (4-{4-[2-(gamma-L-Glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + Diphosphate R11041 S-adenosyl-L-methionine:dTDP-4-oxo-2,6-dideoxy-L-mannose 3-O-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-L-mannose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose R11042 dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose R11043 oleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (12,13 cis-dehydrogenating); Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Linoleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11044 palmitoleoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (12,13 cis-dehydrogenating); Palmitoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (9Z,12Z)-Hexadeca-9,12-dienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11045 S-adenosyl-L-methionine:dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose 3-N,N-dimethyltransferase; 2 S-Adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> 2 S-Adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose R11046 dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose 5-epimerase; dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose R11047 dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-megosamine R11048 (S)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide R11049 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + H2O <=> 6-Hydroxypseudooxynicotine R11050 (R)-6-Hydroxynicotine + Oxygen <=> 5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol + Hydrogen peroxide R11051 dTDP-4-oxo-2,6-dideoxy-D-allose:NADP+ 3-oxidoreductase; dTDP-3,4-dioxo-2,6-dideoxy-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+ R11052 8'-apo-beta-carotenal:oxygen 13,14-dioxygenase (bond-cleaving); all-trans-8'-Apo-beta-carotenal + Oxygen <=> 13-Apo-beta-carotenone + 2,6-Dimethyldeca-2,4,6,8-tetraenedial R11053 UMP,2-oxoglutarate:oxygen oxidoreductase; UMP + 2-Oxoglutarate + Oxygen <=> 5'-Dehydrouridine + Succinate + CO2 + Orthophosphate R11054 dodecanoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7-hydroxylating); Dodecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Hydroxydodecanoate + [Oxidized NADPH---hemoprotein reductase] + H2O R11055 myrcene,NADPH---hemoprotein reductase:O2 oxidoreductase (hydroxylating); Myrcene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (R)-Ipsdienol + [Oxidized NADPH---hemoprotein reductase] + H2O R11056 salicyloyl-CoA,NADH:oxygen oxidoreductase (5-hydroxylating); 2-Hydroxybenzoyl-CoA + NADH + H+ + Oxygen <=> Gentisyl-CoA + NAD+ + H2O R11057 (11Z,14Z)-icosadienoyl-CoA,acceptor:oxygen oxidoreductase (5,6 cis-dehydrogenating); (11Z,14Z)-Icosadienoyl-CoA + Reduced acceptor + Oxygen <=> (5Z,11Z,14Z)-Icosa-5,11,14-trienoyl-CoA + Acceptor + 2 H2O R11058 (11Z,14Z,17Z)-icosatrienoyl-CoA,acceptor:oxygen oxidoreductase (5,6 cis-dehydrogenating); (11Z,14Z,17Z)-Icosatrienoyl-CoA + Reduced acceptor + Oxygen <=> (5Z,11Z,14Z,17Z)-Icosa-5,11,14,17-tetraenoyl-CoA + Acceptor + 2 H2O R11059 8,11,14-eicosatrienoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (5,6-cis-dehydrogenating); 8,11,14-Eicosatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Arachidonyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11060 (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (5,6-cis-dehydrogenating); (8Z,11Z,14Z,17Z)-Icosatetraenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11061 NADPH:demethylphylloquinone oxidoreductase; 2-Phytyl-1,4-naphthoquinone + NADPH + H+ <=> Demethylphylloquinol + NADP+ R11062 phosphatidylethanolamine:phosphatidylglycerol 3-phosphatidyltransferase; Phosphatidylglycerol + Phosphatidylethanolamine <=> Cardiolipin + Ethanolamine R11063 S-methyl-L-methionine:L-homocysteine S-methyltransferase; S-Methyl-L-methionine + L-Homocysteine <=> 2 L-Methionine R11064 L-alanine:L-anticapsin ligase (ADP-forming); L-Anticapsin + L-Alanine + ATP <=> Bacilysin + Orthophosphate + ADP R11065 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase; 3-[(4R)-4-Hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate <=> 3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate R11066 3-[(1E,4R)-4-Hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate <=> (3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate R11067 (3E)-3-[(1R,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADH + H+ <=> 3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD+ R11068 3-[(1R,2S,5R,6S)-5-Hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-Phenylalanine <=> L-Dihydroanticapsin + Phenylpyruvate R11069 Terpentetriene <=> Terpentecin R11070 trans-cinnamate carboxy-lyase; trans-Cinnamate <=> Styrene + CO2 R11071 ferulate carboxy-lyase; Ferulate <=> 4-Vinylguaiacol + CO2 R11072 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one cyclohydrolase; 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one <=> Dihydroneopterin phosphate + H2O R11073 7,8-dihydroneopterin 2'-epimerase; 7,8-Dihydroneopterin <=> 7,8-Dihydromonapterin R11074 (S)-malate carboxy-lyase; (S)-Malate <=> (S)-Lactate + CO2 R11075 L-altarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming); L-Altarate <=> 5-Dehydro-4-deoxy-D-glucarate + H2O R11076 (R)-2-hydroxy-4-methylpentanoyl-CoA hydro-lyase; (R)-2-Hydroxyisocaproyl-CoA <=> Isocaprenoyl-CoA + H2O R11077 galactarate hydro-lyase (3-deoxy-D-threo-hex-2-ulosarate-forming); D-Galactarate <=> (2S,3R)-2,3-Dihydroxy-5-oxohexanedioate + H2O R11078 isoleucine 2-epimerase; L-Isoleucine <=> D-allo-Isoleucine R11079 2-epi-5-epi-valiolone 2-epimerase; 2-epi-5-epi-Valiolone <=> 5-epi-Valiolone R11080 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol 4-epimerase; 3-D-Glucosyl-1,2-diacylglycerol <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol R11081 2-epi-5-epi-valiolone-7-phosphate 2-epimerase; 2-epi-5-epi-Valiolone 7-phosphate <=> 5-epi-Valiolone 7-phosphate R11082 7,8-dihydroneopterin 3'-triphosphate 2'-epimerase; 7,8-Dihydroneopterin 3'-triphosphate <=> 7,8-Dihydromonapterin 3'-triphosphate R11083 D-glucaro-1,4-lactone lyase (ring-opening); D-Glucaro-1,4-lactone <=> 5-Dehydro-4-deoxy-D-glucarate R11084 L-allo-isoleucine:[peptidyl-carrier protein] ligase (AMP-forming); ATP + L-allo-Isoleucine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-allo-Isoleucyl-[peptidyl-carrier protein] R11085 L-arginine:L-amino-acid ligase (ADP-forming); ATP + L-Arginine + L-Amino acid <=> ADP + Orthophosphate + L-Arginyl-L-amino acid R11086 geranyl-diphosphate:2-O-methyl-3-methylflaviolin geranyltransferase (6-linalyl-2-O,3-dimethylflaviolin-forming); Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 6-Linalyl-2-O,3-dimethylflaviolin R11087 geranyl-diphosphate:2-O,3-dimethylflaviolin geranyltransferase (7-O-geranyl-2-O,3-dimethylflaviolin-forming); Geranyl diphosphate + 2-O,3-Dimethylflaviolin <=> Diphosphate + 7-O-Geranyl-2-O,3-dimethylflaviolin R11088 S-adenosyl-3-(methylsulfanyl)propylamine:norspermidine 3-aminopropyltransferase; S-Adenosylmethioninamine + Norspermidine <=> 5'-Methylthioadenosine + Norspermine + H+ R11089 S-adenosyl-3-(methylsulfanyl)propylamine:norspermine 3-aminopropyltransferase; S-Adenosylmethioninamine + Norspermine <=> 5'-Methylthioadenosine + Caldopentamine + H+ R11090 ATP:[protein]-L-arginine N(omega)-phosphotransferase; ATP + Protein-L-arginine <=> ADP + Protein N(omega)-phospho-L-arginine R11091 2,6-Dichloro-p-benzoquinone + NADH + H+ <=> 2,6-Dichlorohydroquinone + NAD+ R11092 2,5-Dichloro-p-benzoquinone + NADH + H+ <=> 2,5-Dichlorohydroquinone + NAD+ R11093 5-Chloro-2-hydroxy-p-benzoquinone + NADH + H+ <=> 5-Chloro-1,2,4-trihydroxybenzene + NAD+ R11094 5'-deoxyadenosine aminohydrolase; 5'-Deoxyadenosine + H2O <=> 5'-Deoxyinosine + Ammonia R11095 [protein]-N(omega)-phospho-L-arginine phosphohydrolase; Protein N(omega)-phospho-L-arginine + H2O <=> Protein-L-arginine + Orthophosphate R11096 24-Methylenecholesterol + NADPH + H+ <=> 24-epi-Campesterol + NADP+ R11097 24-epi-campesterol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating); 24-epi-Campesterol + NADPH + H+ + Oxygen <=> Brassicasterol + NADP+ + 2 H2O R11098 2-iminobutanoate aminohydrolase; 2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia R11099 2-iminopropanoate aminohydrolase; 2-Iminopropanoate + H2O <=> Pyruvate + Ammonia R11100 Dehydroalanine <=> 2-Iminopropanoate R11101 2-Aminobut-2-enoate <=> 2-Iminobutanoate R11102 5-phospho-alpha-D-ribose-1-diphosphate:4-hydroxybenzoate 5-phospho-beta-D-ribofuranosyltransferase (decarboxylating); 5-Phospho-alpha-D-ribose 1-diphosphate + 4-Hydroxybenzoate <=> 4-(beta-D-Ribofuranosyl)phenol 5'-phosphate + CO2 + Diphosphate R11103 L-allo-isoleucyl-[peptidyl-carrier protein]:[peptidyl-carrier protein] L-allo-isoleucyltransferase; L-allo-Isoleucyl-[peptidyl-carrier protein] + Peptidyl-carrier protein <=> Peptidyl-carrier protein + L-allo-Isoleucyl-[peptidyl-carrier protein] R11104 NADH phosphohydrolase; NADH + H2O <=> AMP + NMNH R11105 7-Chloro-L-tryptophan + Oxygen <=> Monodechloroaminopyrrolnitrin + CO2 + 2 H2O R11106 Monodechloroaminopyrrolnitrin + FADH2 + Cl- + Oxygen + H+ <=> Aminopyrrolnitrin + FAD + 2 H2O R11107 Aminopyrrolnitrin + 2 NADPH + 2 Oxygen + 2 H+ <=> Pyrrolnitrin + 2 NADP+ + 2 H2O R11108 palmitoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (4,5 cis-dehydrogenating); Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (4Z)-Hexadec-4-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R11109 palmitoyl-[acyl-carrier protein],reduced-ferredoxin:oxygen oxidoreductase (6,7 cis-dehydrogenating); Hexadecanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (6Z)-Hexadec-6-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R11110 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); (9Z,12Z,15Z,18Z,21Z)-Tetracosapentaenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11111 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); (9Z,12Z,15Z,18Z)-Tetracosatetraenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R11112 Diploptene + S-Adenosyl-L-methionine + Reduced acceptor <=> Adenosylhopane + L-Methionine + Acceptor R11113 Adenosylhopane + H2O <=> Ribosylhopane + Adenine R11114 Ribosylhopane <=> Bacteriohopanetetrol R11115 Bacteriohopanetetrol + UDP-N-acetyl-alpha-D-glucosamine <=> Bacteriohopanetetrol-acetylglucosamine + UDP R11116 Bacteriohopanetetrol-acetylglucosamine + H2O <=> Bacteriohopanetetrol-glucosamine + Acetate R11117 Bacteriohopanetetrol-glucosamine <=> Bacteriohopanetetrol cyclitol ether R11118 Ribosylhopane + L-Glutamate <=> Aminobacteriohopanetriol + 2-Oxoglutarate R11119 L-Tryptophan + Oxygen <=> IPA imine + Hydrogen peroxide R11120 2 IPA imine <=> Chromopyrrolate R11121 Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+ R11122 K-252c + dTDP-L-ristosamine <=> Holyrine A + dTDP R11123 Holyrine A <=> O-Demethyl-N-demethyl-staurosporine R11124 malonyl-CoA:acetyl-CoA malonyltransferase (5-methyl-1-naphthoic acid forming); Acetyl-CoA + 5 Malonyl-CoA + 3 NADPH + 3 H+ <=> 5-Methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+ R11125 malonyl-CoA:acetyl-CoA malonyltransferase (2-hydroxy-5-methyl-1-naphthoic acid forming); Acetyl-CoA + 5 Malonyl-CoA + 2 NADPH + 2 H+ <=> 2-Hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+ R11126 monacolin-J-acid:(S)-2-methylbutanoyl-[acp] (S)-2-methylbutanoyltransferase; Monacolin J acid + (S)-2-Methylbutanoyl-[acp] <=> Lovastatin acid + Acyl-carrier protein R11127 2-O-(alpha-D-glucopyranosyl)glycerol:phosphate beta-D-glucosyltransferase; 2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> beta-D-Glucose 1-phosphate + Glycerol R11128 1,2-beta-D-glucan:phosphate alpha-D-glucosyltransferase; 1,2-beta-D-Glucan(n) + (n-2) Orthophosphate <=> Sophorose + (n-2) D-Glucose 1-phosphate R11129 O-Demethyl-N-demethyl-staurosporine <=> 3'-Demethylstaurosporine R11130 3-(methylsulfanyl)propanoyl-CoA:acceptor 2-oxidoreductase; 3-(Methylthio)propanoyl-CoA + Acceptor <=> 3-(Methylthio)acryloyl-CoA + Reduced acceptor R11131 2 IPA imine <=> Protodeoxyviolaceinic acid R11132 protodeoxyviolaceinate,NADPH:O2 oxidoreductase; Protodeoxyviolaceinic acid + Oxygen + NADPH + H+ <=> Deoxyviolaceinic acid + NADP+ + H2O R11133 Deoxyviolaceinic acid + Oxygen <=> Deoxyviolacein + CO2 + H2O R11134 protodeoxyviolaceinate,NADPH:O2 oxidoreductase; Protodeoxyviolaceinic acid + NADPH + Oxygen + H+ <=> Protoviolaceinic acid + NADP+ + H2O R11135 protoviolaceinate,NADPH:O2 oxidoreductase; Protoviolaceinic acid + Oxygen + NADPH + H+ <=> Violaceinic acid + NADP+ + H2O R11136 Violaceinic acid + Oxygen <=> Violacein + CO2 + H2O R11138 dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose R11139 dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-ristosamine R11140 1,3-alpha-D-glucan:phosphate beta-D-glucosyltransferase; 1,3-alpha-D-Glucan(n) + (n-2) Orthophosphate <=> Nigerose + (n-2) beta-D-Glucose 1-phosphate R11141 pyruvate:(E)-oct-2-enal acetaldehydetransferase (decarboxylating); Pyruvate + trans-2-Octenal <=> (S)-3-Acetyloctanal + CO2 R11142 5beta-cholestane-3alpha,7alpha,12alpha-triol,adrenodoxin:oxygen oxidoreductase (26-hydroxylating); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + 6 Reduced adrenal ferredoxin + 6 H+ + 3 Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + 6 Oxidized adrenal ferredoxin + 4 H2O R11143 [lipoyl-carrier protein]-L-lysine:lipoate ligase (AMP-forming); ATP + (R)-Lipoate + [Lipoyl-carrier protein]-L-lysine <=> Protein N6-(lipoyl)lysine + AMP + Diphosphate R11144 isolithocholate:NAD+ 3-oxidoreductase; Isolithocholate + NAD+ <=> 3-Oxo-5beta-cholanate + NADH + H+ R11145 lithocholate:NADP+ 3-oxidoreductase; Lithocholic acid + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+ R11146 isolithocholate:NADP+ 3-oxidoreductase; Isolithocholate + NADP+ <=> 3-Oxo-5beta-cholanate + NADPH + H+ R11147 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+ R11148 Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide R11149 aurachin B:NAD+ 3-oxidoreductase; Aurachin B + NAD+ + H2O <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+ R11150 4-methyl-5-nitrocatechol,NADH:oxygen 5-oxidoreductase (5-hydroxylating, nitrite-forming); 4-Methyl-5-nitrocatechol + NADH + Oxygen + H+ <=> 2-Hydroxy-5-methylquinone + NAD+ + Nitrite + H2O R11151 rifampicin:NADH:oxygen oxidoreductase (2-hydroxy-2,27-secorifampicin-forming; ring-cleaving); Rifampicin + NADH + Oxygen + H+ <=> 2-Hydroxy-2,27-secorifampicin + NAD+ + H2O R11152 rifampicin:NADPH:oxygen oxidoreductase (2'-N-hydroxyrifampicin-forming); Rifampicin + NADPH + Oxygen + H+ <=> 2-Hydroxy-2,27-secorifampicin + NADP+ + H2O R11153 1,3,7-trimethylurate,NADH:oxygen oxidoreductase (1,3,7-trimethyl-5-hydroxyisourate forming); 1,3,7-Trimethyluric acid + NADH + H+ + Oxygen <=> 1,3,7-Trimethyl-5-hydroxyisourate + NAD+ + H2O R11154 S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase [N4-bis(aminopropyl)spermidine synthesizing]; 2 S-Adenosylmethioninamine + Spermidine <=> 2 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine R11155 protoasukamycin,NADH:oxygen oxidoreductase (4-hydroxylating); Protoasukamycin + NADH + H+ + Oxygen <=> 4-Hydroxyprotoasukamycin + NAD+ + H2O R11156 asperlicin C,NADH:oxygen oxidoreductase; Asperlicin C + NADH + H+ + Oxygen <=> Asperlicin E + NAD+ + H2O R11157 asperlicin C,NADPH:oxygen oxidoreductase; Asperlicin C + NADPH + H+ + Oxygen <=> Asperlicin E + NADP+ + H2O R11158 protodeoxyviolaceinate,NADH:O2 oxidoreductase; Protodeoxyviolaceinic acid + NADH + H+ + Oxygen <=> Protoviolaceinic acid + NAD+ + H2O R11159 S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase (N4-aminopropylspermidine synthesizing); S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + N4-Aminopropylspermidine R11160 S-adenosyl 3-(methylsulfanyl)propylamine:N4-aminopropylspermidine 3-aminopropyltransferase [N4-bis(aminopropyl)spermidine synthesizing]; S-Adenosylmethioninamine + N4-Aminopropylspermidine <=> 5'-Methylthioadenosine + N4-Bis(aminopropyl)spermidine R11161 Dibenzothiophene + Reduced FMN + Oxygen <=> Dibenzothiophene-5-oxide + FMN + H2O R11162 Dibenzothiophene-5-oxide + Reduced FMN + Oxygen <=> Dibenzothiophene-5,5-dioxide + FMN + H2O R11163 dibenzothiophene,FMNH2:oxygen oxidoreductase; Dibenzothiophene + 2 Reduced FMN + 2 Oxygen <=> Dibenzothiophene-5,5-dioxide + 2 FMN + 2 H2O R11164 dibenzothiophene-5,5-dioxide,FMNH2:oxygen oxidoreductase; Dibenzothiophene-5,5-dioxide + Reduced FMN + Oxygen + NADH <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN + H2O + NAD+ + H+ R11165 S-adenosyl-L-methionine:2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] methyltransferase (diphthine methyl ester-[translation elongation factor 2]-forming); 4 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 4 S-Adenosyl-L-homocysteine + Peptide diphthine methyl ester R11166 diphthine methyl ester acylhydrolase; Peptide diphthine methyl ester + H2O <=> Peptide diphthine + Methanol R11168 carbon-monoxide:quinone oxidoreductase; CO + Quinone + H2O <=> CO2 + Hydroquinone R11169 protein-Npi-phospho-L-histidine:2-O-alpha-mannopyranosyl-D-glycerate 6'-O-phosphotransferase; Protein N(pi)-phospho-L-histidine + 2-O-(alpha-D-Mannosyl)-D-glycerate <=> Protein histidine + 2-O-(6-Phospho-alpha-mannosyl)-D-glycerate R11170 protein-Npi-phospho-L-histidine:N,N'-diacetylchitobiose 6'-O-phosphotransferase; Protein N(pi)-phospho-L-histidine + Chitobiose <=> Protein histidine + N,N'-Diacetylchitobiose 6'-phosphate R11171 protein-Npi-phospho-L-histidine:D-galactose 6-O-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Galactose <=> Protein histidine + D-Galactose 6-phosphate R11172 protein-Npi-phospho-L-histidine:cellobiose 6'-O-phosphotransferase; Protein N(pi)-phospho-L-histidine + Cellobiose <=> Protein histidine + 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose R11173 adenosylcobalamin-5'-phosphate phosphohydrolase; Adenosylcobalamin 5'-phosphate + H2O <=> Cobamide coenzyme + Orthophosphate R11174 adenosylcobinamide-GDP:alpha-ribazole adenosylcobinamide-phosphotransferase; Adenosine-GDP-cobinamide + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole <=> GMP + Adenosylcobalamin 5'-phosphate R11175 (S)-nicotine:cytochrome c oxidoreductase (N-methylmimosine-forming); Nicotine + 2 Ferricytochrome c <=> N-Methylmyosmine + 2 Ferrocytochrome c + 2 H+ R11176 N-Methylmyosmine + H2O <=> Pseudooxynicotine R11177 Nicotine + 2 Ferricytochrome c + H2O <=> Pseudooxynicotine + 2 Ferrocytochrome c + 2 H+ R11178 Pseudooxynicotine + H2O <=> 3-Succinoylpyridine + Methylamine R11179 3-Succinoylpyridine + H2O + Acceptor <=> 6-Hydroxy-3-succinoylpyridine + Reduced acceptor R11180 pseudouridine-5'-phosphate phosphohydrolase; Pseudouridine 5'-phosphate + H2O <=> Pseudouridine + Orthophosphate R11181 isatin amidohydrolase; Isatin + H2O <=> Isatinate R11182 acetyl-CoA:glycerone phosphate C-acetyltransferase; Glycerone phosphate + Acetyl-CoA <=> 3-Hydroxy-5-phosphooxypentane-2,4-dione + CoA R11183 ATP:(S)-4,5-dihydroxypentane-2,3-dione 5-phosphotransferase; ATP + (S)-4,5-Dihydroxypentane-2,3-dione <=> ADP + (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione R11184 ATP:acarbose 7IV-phosphotransferase; ATP + Acarbose <=> ADP + Acarbose 7IV-phosphate R11185 ATP:2-epi-5-epi-valiolone 7-phosphotransferase; ATP + 2-epi-5-epi-Valiolone <=> ADP + 2-epi-5-epi-Valiolone 7-phosphate R11186 ditrans,octacis-undecaprenyl-diphosphate:KDO2-lipid-A phosphotransferase; di-trans,poly-cis-Undecaprenyl diphosphate + KDO2-lipid A <=> di-trans,poly-cis-Undecaprenyl phosphate + KDO2-lipid A 1-diphosphate R11187 dihydromonacolin L-[acyl-carrier protein] hydrolase; Dihydromonacolin L-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dihydromonacolin L acid R11188 nucleoside-3',5'-bisphosphate 3'-phosphohydrolase; Nucleoside 3',5'-bisphosphate + H2O <=> Nucleoside 5'-phosphate + Orthophosphate R11189 2,4-dinitroanisole hydrolase; 2,4-Dinitroanisole + H2O <=> Methanol + 2,4-Dinitrophenol R11190 L-Alanyl-gamma-D-glutamyl-L-lysine + H2O <=> L-Alanyl-D-glutamate + L-Lysine R11191 S-adenosyl-L-methionine:6-demethylmitomycin-A 6-O-methyltransferase; S-Adenosyl-L-methionine + 7-Demethylmitomycin A <=> S-Adenosyl-L-homocysteine + Mitomycin A R11192 S-adenosyl-L-methionine:6-demethylmitomycin-B 6-O-methyltransferase; S-Adenosyl-L-methionine + 7-Demethylmitomycin B <=> S-Adenosyl-L-homocysteine + Mitomycin B R11193 S-adenosyl-L-methionine:(4E,8E)-sphinga-4,8-dienine ceramide C-methyltransferase; S-Adenosyl-L-methionine + (4E,8E)-Sphinga-4,8-dienine ceramide <=> S-Adenosyl-L-homocysteine + 9-Methyl-(4E,8E)-sphinga-4,8-dienine ceramide R11194 2,4-dimethylphenol:oxidized azurin oxidoreductase (methyl-hydroxylating); 2,4-Dimethylphenol + 4 Oxidized azurin + H2O <=> 4-Hydroxy-3-methylbenzaldehyde + 4 Reduced azurin + 4 H+ R11195 4-hydroxy-3-methylbenzaldehyde:NADP+ oxidoreductase; 4-Hydroxy-3-methylbenzaldehyde + NADP+ + H2O <=> 4-Hydroxy-3-methylbenzoate + NADPH + H+ R11196 4-Hydroxy-3-methylbenzoate <=> 4-Hydroxyisophthalate R11197 4-Hydroxyisophthalate + Oxygen + NADH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NAD+ + CO2 R11198 4-Hydroxyisophthalate + Oxygen + NADPH + H+ <=> 3,4-Dihydroxybenzoate + H2O + NADP+ + CO2 R11199 sinapoyl-CoA:spermidine N-sinapoyltransferase; 2 Sinapoyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(sinapoyl)spermidine R11200 4-coumaroyl-CoA:spermidine N-(4-coumaroyl)transferase; 2 p-Coumaroyl-CoA + Spermidine <=> 2 CoA + N1,N8-Bis(4-coumaroyl)spermidine R11201 (9Z)-hexadec-9-enoyl-CoA:[Wnt]-L-serine O-hexadecenoyltransferase; Palmitoleoyl-CoA + [Wnt]-L-serine <=> CoA + [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine R11202 [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine acylhydrolase; [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine + H2O <=> [Wnt]-L-serine + (9Z)-Hexadecenoic acid R11203 5'-triphospho-mRNA:GDP 5'-phosphopolyribonucleotidyltransferase [G(5')ppp-mRNA-forming]; 5'-Triphospho-[mRNA] + GDP <=> Diphosphate + G(5')pppPur-mRNA R11204 phosphatidylethanolamine:KDO2-lipid-A 7''-O-ethanolaminephosphotransferase; Phosphatidylethanolamine + KDO2-lipid A <=> 1,2-Diacyl-sn-glycerol + PEtN-KDO2-lipid A R11205 phosphatidylethanolamine:KDO2-lipid-IVA 7''-O-ethanolaminephosphotransferase; Phosphatidylethanolamine + KDO2-lipid IVA <=> 1,2-Diacyl-sn-glycerol + PEtN-KDO2-lipid IV(A) R11206 3-(3,4-dihydroxyphenyl)propanoyl-CoA:(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate CoA-transferase; Dihydrocaffeoyl-CoA + Caffeate <=> 3,4-Dihydroxyphenylpropanoate + Caffeoyl-CoA R11207 [prokaryotic ubiquitin-like protein]:[protein]-L-lysine ligase (ADP-forming); ATP + Prokaryotic ubiquitin-like protein + Protein lysine <=> ADP + Orthophosphate + Pupylated protein R11208 pupylated-protein depupylase; Pupylated protein + H2O <=> Prokaryotic ubiquitin-like protein + Protein lysine R11209 [prokaryotic ubiquitin-like protein]-L-glutamine amidohydrolase; [Prokaryotic ubiquitin-like protein]-L-glutamine + H2O <=> Prokaryotic ubiquitin-like protein + Ammonia R11210 (-)-yatein,2-oxoglutarate:oxygen oxidoreductase (ring-forming); Dihydroanhydropodorhizol + 2-Oxoglutarate + Oxygen <=> Deoxypodophyllotoxin + Succinate + CO2 + H2O R11211 (-)-bursehernin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5'-hydroxylating); Bursehernin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (-)-5'-Demethylyatein + [Oxidized NADPH---hemoprotein reductase] + H2O R11212 (-)-deoxypodophyllotoxin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating); 4'-Demethyldeoxypodophyllotoxin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4'-Demethylepipodophyllotoxin + [Oxidized NADPH---hemoprotein reductase] + H2O R11213 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate (2S)-3-sulfolactaldehyde-lyase (pyruvate-forming); 2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate <=> (2S)-3-Sulfolactaldehyde + Pyruvate R11214 6-deoxy-6-sulfo-D-gluconate hydro-lyase (2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate-forming); 6-Deoxy-6-sulfo-D-gluconate <=> 2-Dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O R11215 6-tuliposide-B D-glucose-lyase (tulipalin-B-forming); 6-Tuliposide B <=> Tulipalin B + D-Glucose R11216 S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase; S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine R11217 S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming); S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine R11218 S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming); S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine R11219 S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming); 2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine R11220 S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming); 2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine R11221 S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming); S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N5-methyl-L-arginine R11222 (-)-matairesinol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming); Matairesinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Pluviatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11223 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid A in lipopolysaccharide palmitoyltransferase; Palmitoylphosphatidylcholine + Hexa-acyl lipid A in lipopolysaccharide <=> 2-Acyl-sn-glycero-3-phosphocholine + Hepta-acyl lipid A in lipopolysaccharide R11224 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate:dolichyl N-acetyl-alpha-D-glucosaminyl-phosphate 3-beta-D-2,3-diacetamido-2,3-dideoxy-beta-D-glucuronosyltransferase; UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate <=> UDP + Archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate R11225 dimethylallyl-phosphate:FMNH2 prenyltransferase; Dimethylallyl phosphate + Reduced FMN <=> Prenylated FMNH2 + Orthophosphate R11226 bacteriochlorophyll a:NADP+ oxidoreductase (geranylgeranyl-reducing); Bacteriochlorophyll a + 3 NADP+ <=> Geranylgeranyl bacteriochlorophyllide a + 3 NADPH + 3 H+ R11227 Pheophorbide a + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Epoxypheophorbide a + 2 Oxidized ferredoxin + H2O R11228 Epoxypheophorbide a + H2O <=> Red chlorophyll catabolite R11229 GTP:gentamicin-C 2''-O-phosphotransferase; GTP + Gentamicin C <=> GDP + Gentamicin C 2''-phosphate R11230 S-adenosyl-L-methionine:(-)-pluviatolide 4-O-methyltransferase; S-Adenosyl-L-methionine + Pluviatolide <=> S-Adenosyl-L-homocysteine + Bursehernin R11231 (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+ R11232 (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADP+ + 2 H2O <=> L-2-Aminoadipate + NADPH + H+ R11233 5-epi-Valiolone <=> Valienone + H2O R11234 ATP:valienone 7-phosphotransferase; Valienone + ATP <=> Valienone 7-phosphate + ADP R11235 Valienone 7-phosphate <=> 1-epi-Valienol 7-phosphate R11236 Valienone 7-phosphate <=> Validone 7-phosphate R11237 1-epi-Valienol 1-phosphate + Nucleoside triphosphate <=> NDP-1-epi-valienol + Diphosphate R11238 Validone 7-phosphate <=> Validamine 7-phosphate R11239 Validamine 7-phosphate + NDP-1-epi-valienol <=> Validoxylamine A 7'-phosphate + NDP R11240 Validoxylamine A 7'-phosphate + H2O <=> Validoxylamine A + Orthophosphate R11241 Validoxylamine A + UDP-glucose <=> Validamycin A + UDP R11242 6-deoxy-6-sulfo-D-glucono-1,5-lactone lactonohydrolase; 6-Deoxy-6-sulfo-D-glucono-1,5-lactone + H2O <=> 6-Deoxy-6-sulfo-D-gluconate R11243 5-epi-Valiolone 7-phosphate + NADH + H+ <=> 5-epi-Valiolol 7-phosphate + NAD+ R11244 5-epi-Valiolol 7-phosphate <=> 1-epi-Valienol 7-phosphate R11245 1-epi-Valienol 7-phosphate <=> 1,7-Diphospho-1-epi-valienol R11246 1,7-Diphospho-1-epi-valienol + Nucleoside triphosphate <=> NDP-1-epi-valienol 7-phosphate + Diphosphate R11247 NDP-1-epi-valienol 7-phosphate + dTDP-4-amino-4,6-dideoxy-D-glucose <=> dTDP-acarviose-7-phosphate R11248 dTDP-acarviose-7-phosphate <=> Acarbose 7IV-phosphate R11249 1-epi-Valienol 7-phosphate <=> 1-epi-Valienol 1-phosphate R11250 NDP-1-epi-valienol + 2-Amino-1,5-anhydro-2-deoxyglucitol <=> Salbostatin 6'-phosphate + NDP R11251 Salbostatin 6'-phosphate + H2O <=> Salbostatin + Orthophosphate R11252 2-Amino-5-epi-valiolone <=> 2-Aminovalienone R11253 5-epi-Valiolone <=> 2-Keto-5-epi-valiolone R11254 2-Keto-5-epi-valiolone <=> 2-Amino-5-epi-valiolone R11255 Cetoniacytone B <=> Cetoniacytone A R11256 4-alpha-D-[(1->4)-alpha-D-glucano]trehalose glucanohydrolase (trehalose-producing); 1-alpha-D-[(1->4)-alpha-D-Glucosyl](n-1)-alpha-D-glucopyranoside + H2O <=> alpha,alpha-Trehalose + Maltodextrin R11257 (2Z)-4,6-dioxohept-2-enedioate acylhydrolase; Maleylpyruvate + H2O <=> Maleic acid + Pyruvate R11258 [protein]-N-pros-phospho-L-histidine phosphohydrolase; Protein N(pi)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate R11259 [protein]-N-tele-phospho-L-histidine phosphohydrolase; Protein N(tau)-phospho-L-histidine + H2O <=> Protein histidine + Orthophosphate R11260 Starch <=> Cyclomaltodextrin R11261 Starch + n H2O <=> (n+1) Maltodextrin R11262 maltodextrin maltohydrolase; Maltodextrin + H2O <=> Maltose R11263 (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase (2-methyl-trans-aconitate forming); 2-Methylcitrate <=> 2-Methyl-trans-aconitate + H2O R11264 2-Methyl-trans-aconitate <=> (Z)-But-2-ene-1,2,3-tricarboxylate R11265 ribostamycin:NAD+ 3''-oxidoreductase; Ribostamycin + NAD+ <=> 3''-Oxoribostamycin + NADH + H+ R11266 xylostasin:NADP+ 3''-oxidoreductase; 3''-Oxoribostamycin + NADPH + H+ <=> Xylostasin + NADP+ R11267 kanamycin-X:oxygen 6'-oxidoreductase; Kanamycin X + Oxygen <=> 6'-Oxokanamycin X + Hydrogen peroxide R11268 kanamycin-C:oxygen 6'-oxidoreductase; Kanamycin C + Oxygen <=> 6'-Oxokanamycin C + Hydrogen peroxide R11269 kanamycin-A:2-oxoglutarate aminotransferase; Kanamycin A + 2-Oxoglutarate <=> 6'-Oxokanamycin X + L-Glutamate R11270 kanamycin-B:2-oxoglutarate aminotransferase; Kanamycin B + 2-Oxoglutarate <=> 6'-Oxokanamycin C + L-Glutamate R11271 UDP-alpha-D-glucose:2'-deamino-2'-hydroxyneamine alpha-D-glucosyltransferase; UDP-glucose + 2'-Deamino-2'-hydroxyneamine <=> UDP + Kanamycin D R11272 UDP-alpha-D-glucose:neamine alpha-D-glucosyltransferase; UDP-glucose + Neamine <=> UDP + 3''-Deamino-3''-hydroxykanamycin B R11273 lividamine:oxygen 6'-oxidoreductase; Lividamine + Oxygen <=> 6'-Oxolividamine + Hydrogen peroxide R11274 Paromamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxolividamine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O R11275 Neamine + S-Adenosyl-L-methionine + Reduced acceptor <=> 4'-Oxonebramine + L-Methionine + 5'-Deoxyadenosine + Acceptor + H2O R11276 lividamine:NADP+ 4'-oxidoreductase; 4'-Oxolividamine + NADPH + H+ <=> Lividamine + NADP+ R11277 nebramine:NADP+ 4'-oxidoreductase; 4'-Oxonebramine + NADPH + H+ <=> Nebramine + NADP+ R11278 UDP-alpha-D-kanosamine:nebramine alpha-D-kanosaminyltransferase; UDP-kanosamine + Nebramine <=> UDP + Tobramycin R11279 kanamycin-B:carbamoyl-phosphate ligase (AMP,phosphate-forming); Kanamycin B + Carbamoyl phosphate + ATP + H2O <=> Nebramycin factor 4 + AMP + Diphosphate + Orthophosphate R11280 paromamine:5-phospho-alpha-D-ribose-1-diphosphate phosphoribosyltransferase; 5-Phospho-alpha-D-ribose 1-diphosphate + Paromamine <=> Diphosphate + 5''-Phosphoribosylparomamine R11281 5''-phosphoribosylparomamine phosphohydrolase; 5''-Phosphoribosylparomamine + H2O <=> 5-Ribosylparomamine + Orthophosphate R11282 UDP-N-acetyl-alpha-D-glucosamine:5-ribosylparomamine N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + 5-Ribosylparomamine <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II R11283 2'''-N-acetyl-6'''-deamino-6'''-hydroxyparomomycin-II hydrolase (acetate-forming); 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II + H2O <=> 6'''-Deamino-6'''-hydroxyparomomycin II + Acetate R11284 6'''-deamino-6'''-hydroxyparomomycin-II:oxygen 6'''-oxidoreductase; 6'''-Deamino-6'''-hydroxyparomomycin II + Oxygen <=> 6'''-Deamino-6'''-oxoparomomycin II + Hydrogen peroxide R11285 paromomycin-II:2-oxoglutarate aminotransferase; Paromomycin II + 2-Oxoglutarate <=> 6'''-Deamino-6'''-oxoparomomycin II + L-Glutamate R11286 paromomycin-II 5'''-epimerase; Paromomycin II <=> Paromomycin R11287 Paromomycin II <=> 5'''-epi-Lividomycin B R11288 5'''-epi-lividomycin-B 5'''-epimerase; 5'''-epi-Lividomycin B <=> Lividomycin B R11289 UDP-D-xylose:paromamine alpha-D-xylosyltransferase; UDP-D-xylose + Paromamine <=> UDP + Gentamicin A2 R11290 gentamicin-A2:NAD+ 3''-oxidoreductase; Gentamicin A2 + NAD+ <=> 3''-Oxogentamicin A2 + NADH + H+ R11291 3''-dehydro-3''-amino-gentamicin-A2:2-oxoglutarate aminotransferase; 3''-Oxogentamicin A2 + L-Glutamate <=> 3''-Amino-3''-deoxygentamicin A2 + 2-Oxoglutarate R11292 S-adenosyl-L-methionine:3''-dehydro-3''-amino-gentamicin-A2 N-methyltransferase; S-Adenosyl-L-methionine + 3''-Amino-3''-deoxygentamicin A2 <=> S-Adenosyl-L-homocysteine + Gentamicin A R11293 S-adenosyl-L-methionine:methylcob(III)alamin:gentamicin-A methyltransferase; Gentamicin A + Methylcobalamin + S-Adenosyl-L-methionine + H+ + e- <=> Gentamicin X2 + Cob(II)alamin + 5'-Deoxyadenosine + L-Methionine R11294 S-adenosyl-L-methionine:methylcob(III)alamin:gentamicin-X2 methyltransferase; Methylcobalamin + Gentamicin X2 + S-Adenosyl-L-methionine <=> Vitamin B12 + Antibiotic G-418 + 5'-Deoxyadenosine + L-Methionine R11295 Gentamicin X2 + FAD <=> 6'-Oxogentamicin X2 + FADH2 R11296 Antibiotic G-418 + FAD <=> 6'-Oxo-G418 + FADH2 R11297 antibiotic-JI-20A:2-oxoglutarate aminotransferase; 6'-Oxogentamicin X2 + L-Glutamate <=> Antibiotic JI-20A + 2-Oxoglutarate R11298 antibiotic-JI-20Ba:2-oxoglutarate aminotransferase; 6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20Ba + 2-Oxoglutarate R11299 antibiotic-JI-20B:2-oxoglutarate aminotransferase; 6'-Oxo-G418 + L-Glutamate <=> Antibiotic JI-20B + 2-Oxoglutarate R11300 Gentamicin C2 <=> Gentamicin C2a R11301 Antibiotic JI-20B <=> Antibiotic JI-20Ba R11302 Antibiotic JI-20A <=> Gentamicin C1a R11303 Antibiotic JI-20Ba <=> Gentamicin C2a R11304 Antibiotic JI-20B <=> Gentamicin C2 R11305 Acarbose 7IV-phosphate <=> Acarbose R11306 UDP-D-glucose:D-glucose 1-alpha-D-glucosyltransferase; UDP-glucose + D-Glucose <=> alpha,alpha-Trehalose + UDP R11307 Cellulose + H2O <=> Cellulose + Cellodextrin R11308 Cellodextrin <=> Cellobiose R11309 Dextran <=> Isomaltose R11310 beta-D-glucose 1,6-phosphomutase; beta-D-Glucose 1-phosphate <=> D-Glucose 6-phosphate R11311 Levan <=> Levanbiose R11312 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> Diphosphate + Thiamin monophosphate + CO2 R11313 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine amidohydrolase; N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-aminomethyl-2-methylpyrimidine + Formate R11314 Thiamine <=> N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine R11315 Pentalen-13-al <=> 1-Deoxypentalenate R11316 G13056 + H2O <=> N-Acetyl-D-glucosamine + G10665 R11317 G05477 + H2O <=> G10920 + N-Acetyl-D-glucosamine R11318 GDP-L-fucose + G10770 <=> GDP + G05477 R11319 ADP:thiamin-diphosphate phosphotransferase; Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP R11320 UDP-D-galactose + Lactosylceramide <=> UDP + iGb3-Cer R11321 UDP-N-acetyl-D-galactosamine + iGb3-Cer <=> UDP + iGb4-Cer R11322 UDP-N-acetyl-D-galactosamine + iGb4-Cer <=> UDP + G02977 R11323 dTTP diphosphohydrolase; dTTP + H2O <=> dTMP + Diphosphate R11324 secalciferol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating); Secalciferol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitetrol + Oxidized adrenal ferredoxin + H2O R11325 ubiquinol:oxygen oxidoreductase (electrogenic, non H+-transporting); 2 Ubiquinol + Oxygen + 4 H+ <=> 2 Ubiquinone + 2 H2O + 4 H+ R11326 D-sedoheptulose-7-phosphate phosphate-lyase (cyclizing; demethyl-4-deoxygadusol-forming); Sedoheptulose 7-phosphate <=> Demethyl-4-deoxygadusol + Orthophosphate + H2O R11327 D-sedoheptulose-7-phosphate phosphate-lyase (cyclizing; 2-epi-valiolone-forming); Sedoheptulose 7-phosphate <=> 2-epi-Valiolone + Orthophosphate R11328 L-tryptophan ammonia-lyase (3-indoleacrylate-forming); L-Tryptophan <=> 3-Indoleacrylate + Ammonia R11329 Fe-coproporphyrin-III ferro-lyase (coproporphyrin-III-forming); Fe-coproporphyrin III + 2 H+ <=> Coproporphyrin III + Fe2+ R11330 D-erythrulose-1-phosphate 3-epimerase; D-Erythrulose 1-phosphate <=> Erythrulose 1-phosphate R11332 L-erythrulose-1-phosphate isomerase; Erythrulose 1-phosphate <=> D-Erythrulose 4-phosphate R11333 D-erythrulose-4-phosphate ketose-aldose isomerase; D-Erythrulose 4-phosphate <=> D-Erythrose 4-phosphate R11334 2-hydroxy-2-methylpropanoyl-CoA CoA-carbonylmutase; 2-Hydroxyisobutanoyl-CoA <=> (S)-3-Hydroxybutanoyl-CoA R11335 ubiquinol:oxygen oxidoreductase (H+-transporting); 2 Ubiquinol + Oxygen + 8 H+ <=> 2 Ubiquinone + 2 H2O + 8 H+ R11336 (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate:NAD+ oxidoreductase; (2S,3R)-2-Hydroxy-3-(indol-3-yl)butanoate + NAD+ <=> (R)-3-(Indol-3-yl)-2-oxobutyrate + NADH + H+ R11337 (R)-2-hydroxyglutarate:NAD+ 2-oxidireductase; (R)-2-Hydroxyglutarate + NAD+ <=> 2-Oxoglutarate + NADH + H+ R11338 2-methylpropane-1,2-diol:NAD+ 1-oxidoreductase; 2-Methylpropane-1,2-diol + NAD+ <=> 2-Hydroxy-2-methylpropanal + NADH + H+ R11339 2-dehydro-3-deoxy-L-rhamnonate:NAD+ 4-oxidoreductase; 2-Dehydro-3-deoxy-L-rhamnonate + NAD+ <=> 2,4-Diketo-3-deoxy-L-fuconate + NADH + H+ R11340 validamycin-A,2-oxoglutarate:oxygen oxidoreductase (6'-hydroxylating); Validamycin A + 2-Oxoglutarate + Oxygen <=> Validamycin B + Succinate + CO2 R11341 D-erythritol-1-phosphate 2-oxidoreductase; D-Erythritol 1-phosphate + NADP+ <=> D-Erythrulose 1-phosphate + NADPH + H+ R11342 D-threitol:NAD+ oxidoreductase; D-Threitol + NAD+ <=> D-Erythrulose + NADH + H+ R11343 butan-1-ol:ferricytochrome c oxidoreductase; 1-Butanol + Ferricytochrome c <=> Butanal + Ferrocytochrome c + H+ R11344 butan-1-ol:quinone oxidoreductase; 1-Butanol + Quinone <=> Butanal + Hydroquinone R11345 DNA-N6-methyladenosine,2-oxoglutarate:oxygen oxidoreductase (formaldehyde-forming); DNA 6-methylaminopurine + 2-Oxoglutarate + Oxygen <=> DNA adenine + Formaldehyde + Succinate + CO2 R11346 5-methylphenazine-1-carboxylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating); 5-Methylphenazine-1-carboxylate + NADH + Oxygen <=> Pyocyanine + NAD+ + CO2 + H2O R11347 resorcinol,NADH:oxygen oxidoreductase (4-hydroxylating); Resorcinol + NADH + H+ + Oxygen <=> Benzene-1,2,4-triol + NAD+ + H2O R11348 resorcinol,FADH2:oxygen oxidoreductase (4-hydroxylating); Resorcinol + FADH2 + Oxygen <=> Benzene-1,2,4-triol + FAD + H2O R11349 testosterone,reduced-ferredoxin:oxygen oxidoreductase (1alpha-hydroxylating); Testosterone + Reduced ferredoxin + Oxygen + H+ <=> 1alpha-Hydroxytestosterone + H2O + Oxidized ferredoxin R11350 2-hydroxy-2-methylpropanal:NAD+ oxidoreductase; 2-Hydroxy-2-methylpropanal + NAD+ + H2O <=> 2-Hydroxy-2-methylpropanoate + NADH + H+ R11351 glyoxal:oxygen oxidoreductase; Glyoxal + H2O + Oxygen <=> Glyoxylate + Hydrogen peroxide R11352 methylglyoxal:oxygen oxidoreductase; Methylglyoxal + H2O + Oxygen <=> Pyruvate + Hydrogen peroxide R11353 2,6-dihydroxybenzoate carboxy-lyase; 2,6-Dihydroxybenzoate <=> Resorcinol + CO2 R11354 RCH2NHR':oxygen oxidoreductase (deaminating); RCH2NHR' + H2O + Oxygen <=> Aldehyde + R'NH2 + Hydrogen peroxide R11355 (25S)-26-Hydroxycholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> (25S)-26-Oxocholest-4-en-3-one + 2 Oxidized ferredoxin + 2 H2O R11356 (25S)-26-Oxocholest-4-en-3-one + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta4-Dafachronic acid + 2 Oxidized ferredoxin + H2O R11357 cholest-4-en-3-one,[reduced ferredoxin]:oxygen oxidoreductase [(25S)-3-oxocholest-4-en-26-oate forming]; Cholest-4-en-3-one + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> Delta4-Dafachronic acid + 6 Oxidized ferredoxin + 4 H2O R11358 cholest-4-en-3-one,reduced-[2Fe-2S]-ferredoxin:oxygen oxidoreductase [(25R)-26-hydroxycholest-4-en-3-one forming]; Cholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-26-Hydroxycholest-4-en-3-one + 2 Oxidized [2Fe-2S] ferredoxin + H2O R11359 (25R)-26-hydroxycholest-4-en-3-one,reduced-[2Fe-2S]-ferredoxin:oxygen oxidoreductase [(25R)-26-oxocholest-4-en-3-one forming]; (25R)-26-Hydroxycholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-26-Oxocholest-4-en-3-one + 2 Oxidized [2Fe-2S] ferredoxin + 2 H2O R11360 (25R)-26-oxocholest-4-en-3-one,reduced-[2Fe-2S]-ferredoxin:oxygen oxidoreductase [(25R)-3-oxocholest-4-en-26-oate forming]; (25R)-26-Oxocholest-4-en-3-one + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> (25R)-3-Oxocholest-4-en-26-oate + 2 Oxidized [2Fe-2S] ferredoxin + H2O R11361 cholest-4-en-3-one,reduced-2Fe-2S]-ferredoxin:oxygen oxidoreductase [(25R)-3-oxocholest-4-en-26-oate forming]; Cholest-4-en-3-one + 6 Reduced [2Fe-2S] ferredoxin + 3 Oxygen <=> (25R)-3-Oxocholest-4-en-26-oate + 6 Oxidized [2Fe-2S] ferredoxin + 4 H2O R11362 3-(1-Carboxyvinyloxy)anthranilate <=> 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate R11363 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate R11364 3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid R11365 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA R11366 L-tyrosine 2,3-aminomutase; L-Tyrosine <=> (S)-beta-Tyrosine R11367 (S)-beta-tyrosine:[peptidyl-carrier protein] ligase (AMP-forming); ATP + (S)-beta-Tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (S)-beta-Tyrosyl-[pcp] R11368 (S)-beta-tyrosyl-[pcp]:FADH2 oxidoreductase; (S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O R11369 (S)-beta-Tyrosyl-[pcp] <=> 3-(4-Hydroxyphenyl)-3-oxopropanoyl-[pcp] R11370 6-methylsalicylate:CoA ligase (AMP-forming); ATP + 6-Methylsalicylate + CoA <=> AMP + Diphosphate + 6-Methylsalicylyl-CoA R11371 S-adenosyl-L-methionine:6-methylsalicylyl-CoA 3-C-methyltransferase; S-Adenosyl-L-methionine + 6-Methylsalicylyl-CoA <=> S-Adenosyl-L-homocysteine + 3,6-Dimethylsalicylyl-CoA R11372 (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate lyase (cyclic pyranopterin phosphate-forming); (8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + H2O <=> Precursor Z + Diphosphate R11373 protoviolaceinate,NADH:O2 oxidoreductase; Protoviolaceinic acid + Oxygen + NADH + H+ <=> Violaceinic acid + NAD+ + H2O R11374 protodeoxyviolaceinate,NADH:O2 oxidoreductase; Protodeoxyviolaceinic acid + Oxygen + NADH + H+ <=> Deoxyviolaceinic acid + NAD+ + H2O R11375 UDP-D-galactose + Paragloboside <=> UDP + IV4Gala-nLc4-Cer R11376 UDP-D-galactose + Globoside <=> UDP + IV4-alpha-Gal-Gb4Cer R11377 UDP-D-galactose + NORint <=> UDP + NOR2 antigen R11378 UDP-N-acetyl-D-galactosamine + Paragloboside <=> UDP + PX2 R11379 UDP-N-acetyl-D-galactosamine + IV4-alpha-Gal-Gb4Cer <=> UDP + NORint R11380 (R)-mandelonitrile:oxygen oxidoreductase; Mandelonitrile + Oxygen <=> Benzoyl cyanide + Hydrogen peroxide R11381 (2E,6E)-farnesol:oxygen oxidoreductase; (2E,6E)-Farnesol + Oxygen <=> 2-trans,6-trans-Farnesal + Hydrogen peroxide R11382 aurachin C:NADH:oxygen oxidoreductase (4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide-forming); Aurachin C + NADH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ + H2O R11383 aurachin C:NADPH:oxygen oxidoreductase (4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide-forming); Aurachin C + NADPH + H+ + Oxygen <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP+ + H2O R11384 aurachin C:NADH:oxygen oxidoreductase (aurachin-C-epoxide-forming); Aurachin C + NADH + H+ + Oxygen <=> Aurachin C epoxide + NAD+ + H2O R11385 aurachin C:NADPH:oxygen oxidoreductase (aurachin-C-epoxide-forming); Aurachin C + NADPH + H+ + Oxygen <=> Aurachin C epoxide + NADP+ + H2O R11386 aurachin-C-epoxide mutase; Aurachin C epoxide <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide R11387 3,6,8-Trihydroxy-2-naphthoate + Reduced acceptor + Oxygen <=> 3,6,7,8-Tetrahydroxy-2-naphthoate + Acceptor + H2O R11388 3,6,7,8-Tetrahydroxy-2-naphthoate <=> 3-Hydroxy-6,7,8-trimethoxy-2-naphthoate R11389 3-Hydroxy-6,7,8-trimethoxy-2-naphthoate <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate R11390 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate + CoA <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA R11391 2-aza-L-tyrosine 2,3-aminomutase; Azatyrosine <=> (R)-2-Aza-beta-tyrosine R11392 (R)-2-aza-beta-tyrosine:[peptidyl-carrier protein] ligase (AMP-forming); ATP + (R)-2-Aza-beta-tyrosine + Peptidyl-carrier protein <=> AMP + Diphosphate + (R)-2-Aza-beta-tyrosyl-[pcp] R11393 (R)-2-aza-beta-tyrosyl-[pcp]:FADH2 oxidoreductase; (R)-2-Aza-beta-tyrosyl-[pcp] + FADH2 + Cl- + Oxygen + H+ <=> (R)-2-Aza-3-chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O R11394 3-deoxy-D-manno-octulosonate:oxygen 8-oxidoreductase; 3-Deoxy-D-manno-octulosonate + Oxygen <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + Hydrogen peroxide R11395 8-amino-3,8-dideoxy-D-manno-octulosonate:2-oxoglutarate aminotransferase; 8-Amino-3,8-dideoxy-D-manno-octulosonate + 2-Oxoglutarate <=> 8-Dehydro-3-deoxy-D-manno-octulosonate + L-Glutamate R11396 CTP:8-amino-3,8-dideoxy-D-manno-octulosonate cytidylyltransferase; CTP + 8-Amino-3,8-dideoxy-D-manno-octulosonate <=> Diphosphate + CMP-8-amino-3,8-dideoxy-beta-D-manno-octulosonate R11397 (1->2)-beta-D-mannan:phosphate beta-D-mannosyltransferase (conformation-inverting); 1,2-beta-Oligomannan(n) + Orthophosphate <=> 1,2-beta-Oligomannan(n-1) + D-Mannose 1-phosphate R11398 beta-D-mannopyranosyl-(1->2)-D-mannopyranose:phosphate alpha-D-mannosyltransferase; beta-1,2-Mannobiose + Orthophosphate <=> D-Mannose + D-Mannose 1-phosphate R11399 dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase; Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein] R11400 ATP:3-O-[N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] 6-phosphotransferase; ATP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] <=> ADP + 3-O-[N-Acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-(6-phospho)mannosyl]-L-threonyl-[protein] R11401 squalene:FAD oxidoreductase (hydroxylating); Squalene + FAD + H2O <=> Hydroxysqualene + FADH2 R11402 GTP:valienol-1-phosphate guanylyltransferase; GTP + Valienol 1-phosphate <=> Diphosphate + GDP-valienol R11403 2-methylpropan-1-amine,FADH2:O2 N-oxidoreductase; 2-Methylpropanamine + FADH2 + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FAD + H2O R11404 2-methylpropan-1-amine,FADH2:O2 N-oxidoreductase; 2-Methylpropanamine + Reduced FMN + Oxygen <=> N-(2-Methylpropanyl)hydroxylamine + FMN + H2O R11405 (S)-scoulerine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(S)-nandinine-forming]; (S)-Scoulerine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-Nandinine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11406 ATP:validone 7-phosphotransferase; ATP + Validone <=> ADP + Validone 7-phosphate R11407 UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13087 R11408 2-phosphinomethylmalate hydro-lyase [3-phosphinomethylmalate-forming]; phosphinomethylmalate isomerase; 2-Phosphinomethylmalate <=> 3-Phosphinomethylmalate R11409 GDP-4-dehydro-alpha-D-rhamnose 3-hydro-lyase; GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia R11410 presqualene-diphosphate diphosphate-lyase (adding water; hydroxysqualene-forming); Presqualene diphosphate + H2O <=> Hydroxysqualene + Diphosphate R11411 2-(glutathion-S-yl)-2-methylbut-3-en-1-ol lyase [(3R)-3,4-epoxy-3-methylbut-1-ene-forming]; 2-(Glutathion-S-yl)-2-methylbut-3-en-1-ol <=> (3R)-3,4-Epoxy-3-methylbut-1-ene + Glutathione R11412 Acetyl-CoA + 3 Malonyl-CoA + Acyl-carrier protein <=> Orsellinate-[acp] + 4 CoA + 3 CO2 + H2O R11413 S-adenosyl-L-methionine:orsellinate-[acp] O-methyltransferase; S-Adenosyl-L-methionine + Orsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 2-Methoxyorsellinate-[acp] R11414 2-Methoxyorsellinate-[acp] + Iodide <=> 5-Iodo-2-methoxyorsellinate-[acp] R11415 5-Iodo-2-methoxyorsellinate-[acp] <=> 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp] R11416 S-adenosyl-L-methionine:3-hydroxy-5-iodo-2-methoxyorsellinate-[acp] O-methyltransferase; S-Adenosyl-L-methionine + 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp] <=> S-Adenosyl-L-homocysteine + 5-Iodo-2,3-dimethoxyorsellinate-[acp] R11417 dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose:calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase; dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin T0 R11418 dTDP-4-deoxy-4-thio-alpha-D-digitoxose:calicheamicin-T0 4-deoxy-4-thio-alpha-D-digitoxosyltransferase; dTDP-4-deoxy-4-thio-alpha-D-digitoxose + Calicheamicin T0 <=> dTDP + 4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 R11419 4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin PsAg + Acyl-carrier protein R11420 dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose:calicheamicin-PsAg 4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentosyltransferase; dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha1(I) R11421 dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose:calicheamicin-alpha3(I) 4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentosyltransferase; dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin alpha3(I) <=> dTDP + Calicheamicin gamma(1)I R11422 dTDP-3'-O-methyl-beta-L-rhamnose:calicheamicin-alpha1(I) 3'-O-methyl-beta-L-rhamnosyltransferase; dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin alpha1(I) <=> dTDP + Calicheamicin gamma(1)I R11423 dTDP-3'-O-methyl-beta-L-rhamnose:calicheamicin-PsAg 3'-O-methyl-beta-L-rhamnosyltransferase; dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin PsAg <=> dTDP + Calicheamicin alpha3(I) R11424 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein],NADH:oxygen oxidoreductase (5-hydroxylating); 3-Hydroxy-4-methylanthranilyl-[aryl-carrier protein] + NADH + H+ + Oxygen <=> 3,5-Dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + NAD+ + H2O R11425 [F-actin]-L-methionine,NADPH:O2 S-oxidoreductase; [F-actin]-L-methionine + NADPH + Oxygen + H+ <=> [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O R11426 (2S)-flavan-3-ol:NADP+ oxidoreductase; (2S,3R)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+ R11427 (2S)-flavan-3-ol:NADP+ oxidoreductase; (2S,3S)-Flavan-3-ol + 2 NADP+ <=> Anthocyanidin with a 3-hydroxy group + 2 NADPH + H+ R11428 cis-4-hydroxy-D-proline:acceptor oxidoreductase; cis-4-Hydroxy-D-proline + Acceptor <=> 1-Pyrroline-4-hydroxy-2-carboxylate + Reduced acceptor R11429 D-Mannose 1-phosphate <=> NDP-D-mannose R11430 NDP-D-mannose <=> NDP-4-oxo-6-deoxy-D-mannose R11431 NDP-4-oxo-6-deoxy-D-mannose <=> NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose R11432 NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose R11433 NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose <=> NDP-2-amino-2,6-dideoxy-D-galactose R11434 NDP-2-amino-2,6-dideoxy-D-galactose <=> NDP-2-methylamino-2,6-dideoxy-D-galactose R11435 8 Malonyl-CoA + 7 NADPH + 7 H+ + Acyl-carrier protein <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+ R11436 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] <=> 1,3,5,7,9,11,13-Pentadecaheptaene + CO2 + Acyl-carrier protein R11439 phosphoenolpyruvate:D-mannose-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase; Phosphoenolpyruvate + D-Mannose 6-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + Orthophosphate R11440 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate-9-phosphate 9-phosphohydrolase; 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + H2O <=> 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate + Orthophosphate R11441 CTP:3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate cytidylyltransferase; CTP + 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonate <=> Diphosphate + CMP-3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate R11442 (E)-4-Hydroxyphenylacetaldehyde oxime <=> (Z)-4-Hydroxyphenylacetaldehyde oxime R11443 L-leucyl-tRNA(Leu):[protein] N-terminal L-lysine leucyltransferase; L-Leucyl-tRNA + L-Lysyl-protein <=> tRNA(Leu) + L-Leucyl-L-lysyl-protein R11444 L-leucyl-tRNA(Leu):[protein] N-terminal L-arginine leucyltransferase; L-Leucyl-tRNA + L-Arginyl-protein <=> tRNA(Leu) + L-Leucyl-L-arginyl-protein R11445 malonyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, methylating, 2-methylbutanoate-forming); 2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine <=> (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O R11446 jasmonate,NADPH:oxygen oxidoreductase (12-hydroxylating); (-)-Jasmonic acid + NADPH + H+ + Oxygen <=> trans-12-Hydroxyjasmonic acid + NADP+ + H2O R11447 tert-butyl alcohol,NADPH:oxygen oxidoreductase; tert-Butyl alcohol + NADPH + H+ + Oxygen <=> 2-Methylpropane-1,2-diol + NADP+ + H2O R11448 butane,NADH:oxygen oxidoreductase; Butane + NADH + H+ + Oxygen <=> 1-Butanol + NAD+ + H2O R11449 tetracycline,NADPH:oxygen oxidoreductase (11a-hydroxylating); Tetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxytetracycline + NADP+ + H2O R11450 eicosanoyl-CoA:methylmalonyl-CoA C-acyltransferase (mycocerosate-forming); Eicosanoyl-CoA + 4 Methylmalonyl-CoA + 8 NADPH + 8 H+ + Acyl-carrier protein <=> C32-Mycocerosyl-[acp] + 5 CoA + 4 CO2 + 8 NADP+ + 4 H2O R11451 stearoyl-CoA:methylmalonyl-CoA C-acyltransferase (mycolipanoate-forming); Stearoyl-CoA + 3 Methylmalonyl-CoA + 6 NADPH + 6 H+ + Acyl-carrier protein <=> C27-Mycolipanoyl-[acp] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O R11452 S-adenosyl-L-methionine:dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose N-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose R11453 S-adenosyl-L-methionine:dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose N-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-D-glucose <=> S-Adenosyl-L-homocysteine + dTDP-D-forosamine R11454 ethylenediaminetetraacetate,FMNH2:O2 oxidoreductase (glyoxylate-forming); EDTA + Reduced FMN + Oxygen <=> Ethylenediaminetriacetic acid + Glyoxylate + FMN + H2O R11455 ethylenediaminetetraacetate,FMNH2:O2 oxidoreductase (glyoxylate-forming); Ethylenediaminetriacetic acid + Reduced FMN + Oxygen <=> Ethylenediamine-N,N'-diacetic acid + Glyoxylate + FMN + H2O R11456 ethylenediaminetetraacetate,FMNH2:O2 oxidoreductase (glyoxylate-forming); EDTA + 2 Reduced FMN + 2 Oxygen <=> Ethylenediamine-N,N'-diacetic acid + 2 Glyoxylate + 2 FMN + 2 H2O R11457 dimethyl sulfone,FMNH2:oxygen oxidoreductase; Dimethyl sulfone + Reduced FMN + Oxygen <=> Methanesulfinic acid + Formaldehyde + FMN + H2O R11458 calciol,ferredoxin:oxygen oxidoreductase (1,25-hydroxylating); Vitamin D3 + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcidiol + 2 Oxidized ferredoxin + H2O R11459 Calcidiol + Oxygen + 2 Reduced ferredoxin + 2 H+ <=> Calcitriol + 2 Oxidized ferredoxin + H2O R11460 ATP:L-erythrulose 4-phosphotransferase; ATP + L-Erythrulose <=> ADP + Erythrulose 1-phosphate R11461 ATP:D-erythrulose 4-phosphotransferase; ATP + D-Erythrulose <=> ADP + D-Erythrulose 4-phosphate R11462 4-methylpentanoyl-CoA:(R)-2-hydroxy-4-methylpentanoate CoA-transferase; Isocaproyl-CoA + (R)-2-Hydroxyisocaproate <=> Isocaproate + (R)-2-Hydroxyisocaproyl-CoA R11463 (2S)-2-amino-4-deoxychorismate pyruvate-hydrolase; 2-Amino-2-deoxyisochorismate + H2O <=> (5S,6S)-6-Amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate + Pyruvate R11464 dTDP-4-oxo-5-C-methyl-L-rhamnose <=> dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose R11465 dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose <=> dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose R11466 dTDP-4-oxo-alpha-D-xylose <=> dTDP-3-methyl-4-oxo-alpha-D-ribopyranose R11467 dTDP-3-methyl-4-oxo-alpha-D-ribopyranose <=> dTDP-madurosamine R11468 dTDP-4-amino-4,6-dideoxy-D-glucose:reduced-ferredoxin:oxygen oxidoreductase; dTDP-4-amino-4,6-dideoxy-D-glucose + Reduced ferredoxin + Oxygen <=> dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Oxidized ferredoxin + H2O R11469 S-adenosyl-L-methionine:dTDP-L-rhamnose 3'-O-methyltransferase; S-Adenosyl-L-methionine + dTDP-L-rhamnose <=> S-Adenosyl-L-homocysteine + dTDP-3-O-methyl-beta-L-rhamnose R11470 dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-deoxy-4-thio-alpha-D-digitoxose R11471 dTDP-glucose:NAD+ 6-oxidoreductase; dTDP-glucose + 2 NAD+ + H2O <=> dTDP-D-glucuronate + 2 NADH + 2 H+ R11472 dTDP-D-glucuronate:NAD+ oxidoreductase (decarboxylating); dTDP-D-glucuronate + NAD+ <=> dTDP-4-oxo-alpha-D-xylose + CO2 + NADH + H+ R11473 dTDP-4-oxo-alpha-D-xylose hydro-lyase (dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene-forming); dTDP-4-oxo-alpha-D-xylose <=> dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + H2O R11474 dTDP-4-oxo-2-deoxy-beta-L-xylose:NADP+ oxidoreductase; dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + NADPH + H+ <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + NADP+ R11475 dTDP-4-amino-2,4-dideoxy-beta-L-xylose:2-oxoglutarate aminotransferase; dTDP-4-amino-2,4-dideoxy-beta-L-xylose + 2-Oxoglutarate <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + L-Glutamate R11476 S-adenosyl-L-methionine:dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase; S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose R11477 tert-amyl alcohol,NADPH:oxygen oxidoreductase (1,2-dehydrogenating); tert-Amyl alcohol + NADPH + H+ + Oxygen <=> Isoprenyl alcohol + NADP+ + 2 H2O R11478 tetracycline:FADH2 oxidoreductase (7-halogenating); Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O R11479 acetyl-CoA:2-aminoethylphosphonate N-acetyltransferase; Acetyl-CoA + 2-Aminoethylphosphonate <=> 2-Acetamidoethylphosphonate + CoA R11480 2-Acetamidoethylphosphonate <=> N-Ethylacetamide R11481 Bialaphos <=> L-Phosphinothricin R11482 4'-O-methylnorbelladine,NADPH---hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming); 4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (4aS,10bR)-Noroxomaritidine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11483 4'-O-methylnorbelladine,NADPH---hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming); 4'-O-Methylnorbelladine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (4aR,10bS)-Noroxomaritidine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11484 bacteriochlorophyllide-c:S-adenosyl-L-methionine oxidoreductase (C-7(1)-hydroxylating); S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> 7-(Hydroxymethyl)bacteriochlorophyllide c + 5'-Deoxyadenosine + L-Methionine R11485 flavodoxin:NADP+ oxidoreductase; Reduced flavodoxin + NADP+ <=> Oxidized flavodoxin + NADPH + H+ R11486 2 Glyphosate + Oxygen <=> 2 1-Aminomethylphosphonic acid + 2 Glyoxylate R11487 sulfite:quinone oxidoreductase; Sulfite + Quinone + H2O <=> Sulfate + Hydroquinone R11488 sulfite,hydrogen sulfide:quinone oxidoreductase; Sulfite + Hydrogen sulfide + Quinone <=> Thiosulfate + Hydroquinone R11489 (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate:oxygen oxidoreductase; (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Hydrogen peroxide R11490 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate:oxygen oxidoreductase; (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1,6-dicarboxylate + Oxygen <=> (5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate + Hydrogen peroxide R11491 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate:oxygen oxidoreductase; (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Oxygen <=> (10aS)-10,10a-Dihydrophenazine-1-carboxylate + Hydrogen peroxide R11492 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate:oxygen oxidoreductase; (1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine-1-carboxylate + Hydrogen peroxide R11493 2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + 2 H2O R11494 magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating); Magnesium protoporphyrin monomethyl ester + 3 S-Adenosyl-L-methionine + H2O <=> Divinylprotochlorophyllide + 3 5'-Deoxyadenosine + 3 H2O R11495 naphthalene-1,2,4,8-tetrol hydro-lyase (juglone-forming); Juglone + H2O <=> Naphthalene-1,2,4,8-tetrol R11496 naphthalene-1,2,4,8-tetrol:oxygen oxidoreductase; 2 Naphthalene-1,2,4,8-tetrol + Oxygen <=> 2 3,5-Dihydroxy-1,4-naphthoquinone + 2 H2O R11497 GDP-valienol:validamine 7-phosphate valienyltransferase; GDP-valienol + Validamine 7-phosphate <=> Validoxylamine A 7'-phosphate + GDP R11498 Valienone 7-phosphate <=> Valienol 7-phosphate R11499 Valienol 7-phosphate <=> Valienol 1-phosphate R11500 (2R,3S,4S)-leucoanthocyanidin:NADP+ 4-oxidoreductase; (2R,3S,4S)-Leucoanthocyanidin + NADP+ <=> (2R,3R)-Dihydroflavonol + NADPH + H+ R11501 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol:hydrogen-peroxide oxidoreductase; 1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> Veratraldehyde + o-Methoxyphenol + Glycolaldehyde + H2O R11502 (3,4-dimethoxyphenyl)methanol:hydrogen-peroxide oxidoreductase; 2 (3,4-Dimethoxyphenyl)methanol + Hydrogen peroxide <=> 2 (3,4-Dimethoxyphenyl)methanol radical + 2 H2O R11503 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol:hydrogen-peroxide oxidoreductase; 1-(4-Hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + Hydrogen peroxide <=> 4-Hydroxy-3-methoxy-benzaldehyde + o-Methoxyphenol + Glycolaldehyde + H2O R11504 1,2-dihydro-beta-NAD:oxygen oxidoreductase (H2O2-forming); 1,2-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide R11505 1,6-dihydro-beta-NAD:oxygen oxidoreductase (H2O2-forming); 1,6-Dihydro-beta-NAD + H+ + Oxygen <=> NAD+ + Hydrogen peroxide R11506 3-vinylbacteriochlorophyllide-d 3(1)-hydro-lyase; Bacteriochlorophyllide d <=> 3-Vinyl bacteriochlorophyllide d + H2O R11507 S-adenosyl-L-methionine:8-ethyl-12-methyl-3-vinylbacteriochlorophyllide-d C-12(1)-methyltransferase; 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine R11508 S-adenosyl-L-methionine:8,12-diethyl-3-vinylbacteriochlorophyllide-d C-8(2)-methyltransferase; 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine R11509 S-adenosyl-L-methionine:12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d C-8(2)-methyltransferase; 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine R11510 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + H2O <=> 8-Ethyl-12-methylbacteriochlorophyllide d R11511 8,12-Diethyl-3-vinylbacteriochlorophyllide d + H2O <=> 8,12-Diethylbacteriochlorophyllide d R11512 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-propylbacteriochlorophyllide d R11513 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H2O <=> 12-Ethyl-8-isobutylbacteriochlorophyllide d R11514 geranylgeranyl-diphosphate:bacteriochlorophyllide-a geranylgeranytransferase; Geranylgeranyl diphosphate + Bacteriochlorophyllide a <=> Geranylgeranyl bacteriochlorophyllide a + Diphosphate R11515 malonyl-[acyl-carrier protein]:L-glutamine amido-ligase (AMP-forming); ATP + Malonyl-[acyl-carrier protein] + L-Glutamine + H2O <=> AMP + Diphosphate + Malonamoyl-[acyl-carrier protein] + L-Glutamate R11516 malonyl-CoA:malonamoyl-[acyl-carrier protein] malonyltransferase; Malonamoyl-[acyl-carrier protein] + 8 Malonyl-CoA <=> 18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + 8 CO2 + 8 CoA R11517 geranylgeranyl-diphosphate:bacteriochlorophyllide-b geranylgeranytransferase; Bacteriochlorophyllide b + Geranylgeranyl diphosphate <=> Geranylgeranyl bacteriochlorophyllide b + Diphosphate R11518 bacteriochlorophyll-b:NADP+ oxidoreductase (geranylgeranyl-reducing); Geranylgeranyl bacteriochlorophyllide b + 3 NADPH + 3 H+ <=> Bacteriochlorophyll b + 3 NADP+ R11519 protochlorophyllide-a:ferredoxin C-8(1)-oxidoreductase; Protochlorophyllide + 2 Oxidized ferredoxin <=> Divinylprotochlorophyllide + 2 Reduced ferredoxin + 2 H+ R11520 S-adenosyl-L-methionine:4-amino-anhydrotetracycline N-methyltransferase; S-Adenosyl-L-methionine + 4-Amino-anhydrotetracycline <=> S-Adenosyl-L-homocysteine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline R11521 S-adenosyl-L-methionine:4-methylamino-4-de(dimethylamino)anhydrotetracycline N-methyltransferase; S-Adenosyl-L-methionine + 4-Methylamino-4-de(dimethylamino)anhydrotetracycline <=> S-Adenosyl-L-homocysteine + Anhydrotetracycline R11522 Fe-coproporphyrin III:hydrogen peroxide oxidoreductase (decarboxylating); Fe-coproporphyrin III + 2 Hydrogen peroxide <=> Heme + 2 CO2 + 4 H2O R11523 [Sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine <=> [Sulfur-carrier protein]-Gly-Gly-L-Cys R11524 [CysO sulfur-carrier protein]-L-cysteine carboxypeptidase; [Sulfur-carrier protein]-Gly-Gly-L-Cys + H2O <=> L-Cysteine + Sulfur-carrier protein R11525 oxytetracycline,NADPH:oxygen oxidoreductase (11a-hydroxylating); Oxytetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxyoxytetracycline + NADP+ + H2O R11526 chlortetracycline,NADPH:oxygen oxidoreductase (11a-hydroxylating); Chlortetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O R11527 1-acyl-sn-glycerol 3-phosphate phosphohydrolase; 1-Acyl-sn-glycerol 3-phosphate + H2O <=> 1-Acylglycerol + Orthophosphate R11528 L-cysteine:sulfur-acceptor sulfurtransferase; L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine R11529 [enzyme]-S-sulfanylcysteine:sulfur-acceptor sulfurtransferase; [Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine R11530 ADP-alpha-D-glucose:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (configuration-retaining); ADP-glucose + D-Glucose 1-phosphate <=> ADP + alpha-Maltose 1-phosphate R11531 bacteriochlorophyllide-g:ferredoxin C-8(1)-oxidoreductase; Bacteriochlorophyllide g + 2 Oxidized ferredoxin + ADP + Orthophosphate <=> Divinyl chlorophyllide a + 2 Reduced ferredoxin + ATP + H2O + 2 H+ R11532 2-aminomuconate aminohydrolase (2-hydroxymuconate-forming); 2-Aminomuconate + H2O <=> 2-Hydroxymuconate + Ammonia R11533 S-adenosyl-L-methionine:phenazine-1-carboxylate 5-methyltransferase; S-Adenosyl-L-methionine + Phenazine-1-carboxylate + H+ <=> S-Adenosyl-L-homocysteine + 5-Methylphenazine-1-carboxylate R11534 S-adenosyl-L-methionine:N-demethylindolmycin N-methyltransferase; S-Adenosyl-L-methionine + N-Demethylindolmycin <=> S-Adenosyl-L-homocysteine + Indolmycin R11535 ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase; ADP + alpha-D-Ribose 1-phosphate <=> AMP + D-Ribose 1,5-bisphosphate R11536 ATP:erythritol 1-phosphotransferase; ATP + Erythritol <=> ADP + D-Erythritol 1-phosphate R11537 ATP + 17-(4-Hydroxyphenyl)heptadecanoate <=> Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl adenylate R11538 ATP + 19-(4-Hydroxyphenyl)nonadecanoate <=> Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl adenylate R11539 lithocholoyl-CoA:cholate CoA-transferase; Lithocholoyl-CoA + Cholic acid <=> Lithocholic acid + Choloyl-CoA R11540 poly(ethylene terephthalate) hydrolase; Poly(ethylene terephthalate)(n) + H2O <=> Poly(ethylene terephthalate)(n-1) + 4-(2-Hydroxyethoxycarbonyl)benzoate R11541 4-[(2-hydroxyethoxy)carbonyl]benzoate acylhydrolase; 4-(2-Hydroxyethoxycarbonyl)benzoate + H2O <=> Terephthalate + Ethylene glycol R11542 2-aminobenzoylacetyl-CoA hydrolase; (2-Aminobenzoyl)acetyl-CoA + H2O <=> (2-Aminobenzoyl)acetate + CoA R11543 6-sulfo-alpha-D-quinovosyl diacylglycerol 6-sulfo-D-quinovohydrolase (configuration-retaining); Sulfoquinovosyldiacylglycerol + H2O <=> 6-Sulfo-alpha-D-quinovose + 1,2-Diacyl-sn-glycerol R11544 beta-1,2-mannotriose mannohydrolase; beta-1,2-Mannotriose + H2O <=> beta-1,2-Mannobiose + alpha-D-Mannose R11545 S-adenosyl-L-methionine:(-)-5'-demethylyatein 5'-O-methyltransferase; S-Adenosyl-L-methionine + (-)-5'-Demethylyatein <=> S-Adenosyl-L-homocysteine + Dihydroanhydropodorhizol R11546 S-adenosyl-L-methionine:methanethiol S-methyltransferase; S-Adenosyl-L-methionine + Methanethiol <=> S-Adenosyl-L-homocysteine + Dimethyl sulfide R11547 L-leucyl-tRNA(Leu):[protein] N-terminal L-glutamate leucyltransferase; L-Leucyl-tRNA + L-Glutamyl-protein <=> tRNA(Leu) + L-Leucyl-L-glutamyl-protein R11548 L-leucyl-tRNA(Leu):[protein] N-terminal L-aspartate leucyltransferase; L-Leucyl-tRNA + L-Aspartyl-protein <=> tRNA(Leu) + L-Leucyl-L-aspartyl-protein R11549 feruloyl-CoA,2-oxoglutarate:oxygen oxidoreductase (6-hydroxylating); Feruloyl-CoA + 2-Oxoglutarate + Oxygen <=> 6-Hydroxyferuloyl-CoA + Succinate + CO2 R11550 6-Hydroxyferuloyl-CoA <=> Scopoletin + CoA R11551 geranyl-diphosphate phosphohydrolase; Geranyl diphosphate + H2O <=> Geranyl phosphate + Orthophosphate R11552 geranyl-phosphate phosphohydrolase; Geranyl phosphate + H2O <=> Geraniol + Orthophosphate R11553 ATP:D-ribose-5-phosphate adenylyltransferase; ATP + D-Ribose 5-phosphate <=> Diphosphate + ADP-ribose R11554 ATP:3-hydroxy-4-methylanthranilate adenylyltransferase; ATP + 3-Hydroxy-4-methylanthranilate <=> Diphosphate + (3-Hydroxy-4-methylanthranilyl)adenylate R11555 phosphatidylethanolamine:KDO2-lipid-A ethanolaminephosphotransferase; Phosphatidylethanolamine + KDO2-lipid A <=> Diacylglycerol + KDO2-lipid A 1-(2-aminoethyl diphosphate) R11556 phosphatidylethanolamine:KDO2-lipid-A ethanolaminephosphotransferase; Phosphatidylethanolamine + KDO2-lipid A <=> Diacylglycerol + KDO2-lipid A 4'-(2-aminoethyl diphosphate) R11557 phosphatidylethanolamine:KDO2-lipid-A-1-(2-aminoethyl diphosphate) ethanolaminephosphotransferase; Phosphatidylethanolamine + KDO2-lipid A 1-(2-aminoethyl diphosphate) <=> Diacylglycerol + KDO2-lipid A 1,4'-bis(2-aminoethyl diphosphate) R11558 CDP-glycerol:N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol glycerophosphotransferase; CDP-glycerol + N-Acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol <=> CMP + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11559 protein N-terminal asparagine amidohydrolase; L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia R11560 protein N-terminal glutamine amidohydrolase; L-Glutaminyl-peptide + H2O <=> L-Glutamyl-protein + Ammonia R11561 N5-phenyl-L-glutamine amidohydrolase; N5-Phenyl-L-glutamine + H2O <=> L-Glutamate + Aniline R11562 protein-Nomega-(1-hydroxy-2-oxopropyl)-L-arginine hydrolase; Protein Nomega-(1-hydroxy-2-oxopropyl)-L-arginine + H2O <=> Protein-L-arginine + Lactate R11563 protein-N6-(1-hydroxy-2-oxopropyl)-L-lysine hydrolase; Protein N6-(1-hydroxy-2-oxopropyl)-L-lysine + H2O <=> Protein lysine + Lactate R11564 protein-S-(1-hydroxy-2-oxopropyl)-L-cysteine hydrolase; Protein S-(1-hydroxy-2-oxopropyl)-L-cysteine + H2O <=> [Protein]-L-cysteine + Lactate R11565 7alpha,12alpha-dihydroxy-3-oxochol-4-enoyl-CoA hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoyl-CoA-forming); 7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O R11566 7alpha-hydroxy-3-oxochol-4-enoyl-CoA hydro-lyase (3-oxochola-4,6-dienoyl-CoA-forming); 7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-Oxochola-4,6-dien-24-oyl-CoA + H2O R11568 2 (1R,6S)-6-Amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O R11569 (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + H2O R11570 (1R,6R)-1,4,5,5a,6,9-Hexahydrophenazine-1,6-dicarboxylate + Oxygen <=> (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate + Hydrogen peroxide + CO2 R11571 (1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate <=> (1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate R11572 (1R)-1,4,5,10-Tetrahydrophenazine-1-carboxylate + Oxygen <=> 5,10-Dihydrophenazine + Hydrogen peroxide + CO2 R11573 5,10-Dihydrophenazine + Oxygen <=> Phenazine + Hydrogen peroxide R11574 (5aS)-5,5a-Dihydrophenazine-1,6-dicarboxylate <=> 5,10-Dihydrophenazine-1,6-dicarboxylate R11575 5,10-Dihydrophenazine-1,6-dicarboxylate + Oxygen <=> Phenazine-1,6-dicarboxylic acid + Hydrogen peroxide R11576 (10aS)-10,10a-Dihydrophenazine-1-carboxylate <=> 5,10-Dihydrophenazine-1-carboxylate R11577 5,10-Dihydrophenazine-1-carboxylate + Oxygen <=> Phenazine-1-carboxylate + Hydrogen peroxide R11578 Phenazine-1-carboxylate + NADH + Oxygen + H+ <=> 1-Hydroxyphenazine + NAD+ + CO2 + H2O R11579 protoheme,reduced ferredoxin:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating); Heme + 6 Reduced ferredoxin + 3 Oxygen + 6 H+ <=> Biliverdin + Fe2+ + CO + 6 Oxidized ferredoxin + 3 H2O R11580 S-adenosyl-L-methionine:cobalt-factor III 17-methyltransferase (ring contracting); S-Adenosyl-L-methionine + Cobalt-factor III + Reduced acceptor <=> S-Adenosyl-L-homocysteine + Cobalt-precorrin 4 + Acceptor R11581 GTP:molybdenum cofactor guanylyltransferase; Molybdoenzyme molybdenum cofactor + GTP <=> Guanylyl molybdenum cofactor + Diphosphate R11582 CTP:molybdenum cofactor cytidylyltransferase; Molybdoenzyme molybdenum cofactor + CTP <=> Cytidylyl molybdenum cofactor + Diphosphate R11583 L-cysteine:molybdenum cofactor sulfurtransferase; Molybdoenzyme molybdenum cofactor + L-Cysteine + Reduced acceptor + H+ <=> Thio-molybdenum cofactor + L-Alanine + H2O + Acceptor R11584 isobutyryl-CoA:malonyl-CoA acyltransferase; 2-Methylpropanoyl-CoA + 3 Malonyl-CoA <=> 4 CoA + 3 CO2 + Phlorisobutyrophenone R11585 2,3,5,6-tetrachlorohydroquinone:NAD+ oxidoreductase; Tetrachlorohydroquinone + NAD+ <=> Chloranil + NADH + H+ R11586 anthraniloyl-CoA:malonyl-CoA anthraniloyltransferase; Anthraniloyl-CoA + L-Cysteinyl-protein <=> S-Anthraniloyl-L-cysteinyl-protein + CoA R11587 anthraniloyl-CoA:malonyl-CoA anthraniloyltransferase; S-Anthraniloyl-L-cysteinyl-protein + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein R11588 anthraniloyl-CoA anthraniloyltransferase; Anthraniloyl-CoA + Malonyl-CoA <=> (2-Aminobenzoyl)acetyl-CoA + CoA + CO2 R11589 octanoyl-CoA:2-aminobenzoylacetate octanoyltransferase; S-Octanoyl-L-cysteinyl-protein + (2-Aminobenzoyl)acetate <=> 1-(2-Aminophenyl)decane-1,3-dione + CO2 + L-Cysteinyl-protein R11590 octanoyl-CoA:2-aminobenzoylacetate octanoyltransferase; 1-(2-Aminophenyl)decane-1,3-dione <=> 2-Heptyl-4(1H)-quinolone + H2O R11591 (R)-lactate:quinone 2-oxidoreductase; (R)-Lactate + Quinone <=> Pyruvate + Hydroquinone R11592 ribonucleoside-5'-triphosphate:formate 2'-oxidoreductase; Ribonucleoside triphosphate + Formate <=> Deoxynucleoside triphosphate + CO2 + H2O R11593 (R)-2-hydroxyglutarate:pyruvate oxidoreductase [(R)-lactate-forming]; Pyruvate + (R)-2-Hydroxyglutarate <=> (R)-Lactate + 2-Oxoglutarate R11594 L-proline,2-oxoglutarate:oxygen oxidoreductase (cis-4-hydroxylating); L-Proline + 2-Oxoglutarate + Oxygen <=> cis-4-Hydroxy-L-proline + Succinate + CO2 R11595 S-adenosyl-L-methionine:(S)-reticuline N-methyltransferase; S-Adenosyl-L-methionine + (S)-Reticuline <=> S-Adenosyl-L-homocysteine + (S)-Tembetarine R11597 (E)-2-methylbutanal oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (E)-2-Methylbutanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11598 (E)-2-methylpropanal oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (E)-2-Methylpropanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Acetone cyanohydrin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11599 UDP-alpha-D-galactose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-galactosyltransferase (configuration-retaining); UDP-alpha-D-galactose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> UDP + alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R11600 gamma-butyrobetainyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase; 4-Trimethylammoniobutanoyl-CoA + Electron-transferring flavoprotein <=> (E)-4-(Trimethylammonio)but-2-enoyl-CoA + Reduced electron-transferring flavoprotein R11601 GDP-beta-L-fucose:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R alpha-(1,2)-L-fucosyltransferase (configuration-inverting); GDP-L-fucose + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + alpha-L-Fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R R11602 geranyl-diphosphate:umbelliferone 8-geranyltransferase; Geranyl diphosphate + Umbelliferone <=> Diphosphate + 8-Geranylumbelliferone R11603 geranyl-diphosphate:esculetin 8-geranyltransferase; Geranyl diphosphate + Esculetin <=> Diphosphate + 8-Geranylesculetin R11604 L-arginine:oxygen oxidoreductase (deaminating); L-Arginine + H2O + Oxygen <=> 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide R11606 sulfite,hydrogen sulfide:ferricytochrome-c3 oxidoreductase (thiosulfate-forming); Sulfite + Hydrogen sulfide + 2 Ferricytochrome c3 <=> Thiosulfate + 2 Ferrocytochrome c3 R11607 3-aminobutanoyl-CoA:2-oxoglutarate aminotransferase; 3-Aminobutanoyl-CoA + 2-Oxoglutarate <=> Acetoacetyl-CoA + L-Glutamate R11608 ATP + 4-Hydroxybenzoate <=> Diphosphate + 4-Hydroxybenzoyl-adenylate R11609 dimethylallyl-diphosphate:2-acylphloroglucinol 4-dimethylallyltransferase; Dimethylallyl diphosphate + 2-Acylphloroglucinol <=> Diphosphate + 2-Acyl-4-prenylphloroglucinol R11610 dimethylallyl-diphosphate:2-acyl-4-prenylphloroglucinol 6-dimethylallyltransferase; Dimethylallyl diphosphate + 2-Acyl-4-prenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol R11611 dimethylallyl-diphosphate:2-acyl-4-prenylphloroglucinol 6-dimethylallyltransferase; Dimethylallyl diphosphate + 2-Acyl-4,6-bisprenylphloroglucinol <=> Diphosphate + 2-Acyl-4,6,6-trisprenylcyclohexa-2,4-dien-1-one R11612 CDP-glycerol:4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol glycerophosphotransferase; CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11613 CDP-ribitol:4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol ribitylphosphotransferase; CDP-ribitol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-[1-D-Ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11614 CDP-ribitol:4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol ribitolphosphotransferase; n CDP-ribitol + 4-O-[1-D-Ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-[(1-D-Ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11615 malonyl-CoA:4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] malonyltransferase (4-hydroxyphenylalkanoate-forming); 4-Hydroxybenzoyl-[acp] + 8 Malonyl-CoA + 16 NADPH + 16 H+ <=> 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] + 8 CO2 + 8 CoA + 16 NADP+ + 8 H2O R11616 malonyl-CoA:4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] malonyltransferase (4-hydroxyphenylalkanoate-forming); 4-Hydroxybenzoyl-[acp] + 9 Malonyl-CoA + 18 NADPH + 18 H+ <=> 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O R11617 oxamate amidohydrolase; Oxamate + H2O <=> Oxalate + Ammonia R11618 alditol:oxygen oxidoreductase; Alditol + Oxygen <=> Aldose + Hydrogen peroxide R11619 3',5'-cyclic AMP aminohydrolase; 3',5'-Cyclic AMP + H2O <=> 3',5'-Cyclic IMP + Ammonia R11620 D-sorbitol:oxygen oxidoreductase; D-Sorbitol + Oxygen <=> alpha-D-Glucose + Hydrogen peroxide R11621 CDP-ribitol:4-O-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol ribitolphosphotransferase; 4-O-Di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + n CDP-ribitol <=> 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + n CMP R11622 jasmonoyl-L amino acid amidohydrolase; Jasmonoyl-L-amino acid + H2O <=> (-)-Jasmonic acid + L-Amino acid R11623 D-tagatose 6-phosphate 4-epimerase; D-Tagatose 6-phosphate <=> D-Fructose 6-phosphate R11624 D-tagaturonate 3-epimerase; D-Tagaturonate <=> D-Fructuronate R11625 cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming); cis-3-Hydroxy-L-proline <=> 1-Pyrroline-2-carboxylate + H2O R11626 Ni-sirohydrochlorin nickel-lyase (sirohydrochlorin-forming); Sirohydrochlorin + Nickel(2+) <=> Nickel-sirohydrochlorin + 2 H+ R11627 Ni-sirohydrochlorin:L-glutamine amido-ligase (ADP-forming); Nickel-sirohydrochlorin + 2 ATP + 2 L-Glutamine + 2 H2O <=> Nickel-sirohydrochlorin a,c-diamide + 2 ADP + 2 L-Glutamate + 2 Orthophosphate R11628 Ni-sirohydrochlorin a,c-diamide reductive cyclo-ligase (ADP-forming); ATP + Nickel-sirohydrochlorin a,c-diamide + 3 Reduced acceptor + H2O <=> ADP + Orthophosphate + 15,17(3)-Seco-F430-17(3)-acid + 3 Acceptor R11629 15,17(3)-seco-F430-17(3)-acid cyclo-ligase (ADP-forming); 15,17(3)-Seco-F430-17(3)-acid + ATP <=> Coenzyme F430 + ADP + Orthophosphate R11630 4-hydroxyproline-betaine 2-epimerase; (-)-Betonicine <=> Turicine R11631 proline-betaine 2-epimerase; Stachydrine <=> D-Proline betaine R11632 L-carnitine:CoA ligase (AMP-forming); ATP + L-Carnitine + CoA <=> AMP + Diphosphate + L-Carnitinyl-CoA R11633 GTP:formate 2'-oxidoreductase; GTP + Formate <=> dGTP + CO2 + H2O R11634 ATP:formate 2'-oxidoreductase; ATP + Formate <=> dATP + CO2 + H2O R11635 UTP:formate 2'-oxidoreductase; UTP + Formate <=> dUTP + CO2 + H2O R11636 CTP:formate 2'-oxidoreductase; CTP + Formate <=> dCTP + CO2 + H2O R11637 galactitol:NAD+ 2-oxidoreductase (L-tagatose-forming); Galactitol + NAD+ <=> L-Tagatose + NADH + H+ R11638 D-altritol:NAD+ 5-oxidoreductase; D-Altritol + NAD+ <=> D-Tagatose + NADH + H+ R11639 (Z)-2-Methylbutanal oxime <=> 2-Methylbutanenitrile + H2O R11640 2-Methylbutanenitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (2R)-2-Hydroxy-2-methylbutanenitrile + [Oxidized NADPH---hemoprotein reductase] + H2O R11641 (Z)-2-Methylpropanal oxime <=> Isobutyronitrile + H2O R11642 Isobutyronitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Acetone cyanohydrin + [Oxidized NADPH---hemoprotein reductase] + H2O R11643 acyl-CoA,reduced acceptor:oxygen oxidoreductase (15,16 cis-dehydrogenating); (9Z,12Z)-Hexadeca-9,12-dienoyl-CoA + Reduced acceptor + Oxygen <=> (9Z,12Z)-Hexadeca-9,12,15-trienoyl-CoA + Acceptor + 2 H2O R11644 acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase [omega(9-4),omega(9-5) cis-dehydrogenating]; Linoleoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Pinolenoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O R11645 acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase [omega(9-4),omega(9-5) cis-dehydrogenating]; alpha-Linolenoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Coniferonoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O R11646 L-homomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase; L-Polyhomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> omega-(Methylthio)-(E)-alkanal oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O R11647 L-Polyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N-Hydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O R11648 L-N-Hydroxypolyhomomethionine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> L-N,N-Dihydroxypolyhomomethionine + [Oxidized NADPH---hemoprotein reductase] + H2O R11649 L-N,N-Dihydroxypolyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime + CO2 + H2O R11650 (E)-omega-(methylthio)alkananaldoxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating); omega-(Methylthio)-(E)-alkanal oxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11651 omega-(Methylthio)-(E)-alkanal oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-omega-(methylthio)alkane + [Oxidized NADPH---hemoprotein reductase] + H2O R11652 1-aci-Nitro-omega-(methylthio)alkane + Glutathione <=> (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O R11653 phenol,FADH2:oxygen oxidoreductase (2-hydroxylating); Phenol + FADH2 + Oxygen <=> Catechol + FAD + H2O R11654 menaquinone-9 oxidoreductase (beta-dihydromenaquinone-9-forming); Menaquinone-9 + Reduced acceptor <=> beta-Dihydromenaquinone-9 + Acceptor R11655 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate:NAD+ dehydrogenase (L-2,3-diaminopropanoate-forming); N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O <=> 2-Oxoglutarate + L-2,3-Diaminopropanoate + NADH + H+ R11656 ent-sandaracopimaradiene,NADPH:oxygen oxidoreductase (ent-sandaracopimaradien-3beta-ol forming); (+)-Sandaracopimaradiene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Sandaracopimaradien-3beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R11657 ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin E forming); ent-Sandaracopimaradien-3beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Oryzalexin E + [Oxidized NADPH---hemoprotein reductase] + H2O R11658 ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin D forming); ent-Sandaracopimaradien-3beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Oryzalexin D + [Oxidized NADPH---hemoprotein reductase] + H2O R11659 2-(glutathione-S-yl)-hydroquinone:glutathione oxidoreductase; 2-(Glutathione-S-yl)-hydroquinone + Glutathione <=> Glutathione disulfide + Hydroquinone R11660 chitin,hydrogen-donor:oxygen oxidoreductase (N-acetyl-beta-D-glucosaminyl C1-hydroxylating/C4-dehdrogenating); Chitin(n+m) + Reduced acceptor + Oxygen <=> [(1->4)-N-Acetyl-beta-D-glucosaminyl]n-(1->4)-N-acetyl-2-deoxy-2-amino-D-glucono-1,5-lactone + Chitin(m) + Acceptor + H2O R11661 2-methyl-3-n-amyl-dihydropyrrole:amine oxidoreductase; 2-Methyl-3-n-amyl-dihydropyrrole + FAD <=> 2-Methyl-3-n-amyl-pyrrole + FADH2 R11662 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole + ATP <=> Prodigiosin + ADP + Orthophosphate R11663 4-keto-2-undecylpyrroline,NADPH: oxidoreductase; 4-Keto-2-undecylpyrroline + NADPH + H+ <=> 2-Undecylpyrrole + NADP+ + H2O R11664 Dodecanoic acid + Malonyl-CoA + Glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA R11665 Pyrrole-2-carbonyl-[pcp] + Acyl-carrier protein <=> Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Peptidyl-carrier protein R11666 4-keto-2-undecylpyrroline,NADH: oxidoreductase; 4-Keto-2-undecylpyrroline + NADH + H+ <=> 2-Undecylpyrrole + NAD+ + H2O R11667 Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Malonyl-CoA + L-Serine <=> 4-Hydroxy-2,2'-bipyrrole-5-methanol + CoA + Acyl-carrier protein + 2 CO2 + H2O R11668 4-hydroxy-2,2'-bipyrrole-5-methanal:NADP+ oxidoreductase; 4-Hydroxy-2,2'-bipyrrole-5-methanol + NADP+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADPH + H+ R11669 4-hydroxy-2,2'-bipyrrole-5-methanal:NAD+ oxidoreductase; 4-Hydroxy-2,2'-bipyrrole-5-methanol + NAD+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADH + H+ R11670 S-adenosyl-L-methionine:4-hydroxy-2,2'-bipyrrole-5-carbaldehyde 4-O-methyltransferase; 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-methionine <=> 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-homocysteine R11671 Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein] R11672 (S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid R11673 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole + ATP <=> Undecylprodigiosin + ADP + Orthophosphate R11674 3-(3,4-dihydroxyphenyl)propanoyl-CoA:NAD+,ferredoxin oxidoreductase; Dihydrocaffeoyl-CoA + 2 NAD+ + 2 Reduced ferredoxin <=> Caffeoyl-CoA + 2 NADH + 2 Oxidized ferredoxin R11675 butanoyl-CoA:NAD+, ferredoxin oxidoreductase; Butanoyl-CoA + 2 NAD+ + 2 Reduced ferredoxin <=> Crotonoyl-CoA + 2 NADH + 2 Oxidized ferredoxin R11676 lactate:NAD+,ferredoxin oxidoreductase; Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin R11677 (2S)-3-sulfolactaldehyde:NAD+ oxidoreductase; (2S)-3-Sulfolactaldehyde + NAD+ + H2O <=> (S)-3-Sulfolactate + NADH + H+ R11678 (2S)-3-sulfolactaldehyde:NADP+ oxidoreductase; (2S)-3-Sulfolactaldehyde + NADP+ + H2O <=> (S)-3-Sulfolactate + NADPH + H+ R11679 (S)-2-amino-6-oxohexanoate:NADP+ oxidoreductase (ATP-forming); L-2-Aminoadipate 6-semialdehyde + NADP+ + AMP + Diphosphate <=> L-2-Aminoadipate + NADPH + H+ + ATP R11680 1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate R11681 S-adenosyl-L-methionine:deacetylisoipecoside 6-O-methyltransferase; Deacetylisoipecoside + S-Adenosyl-L-methionine <=> 6-O-Methyldeacetylisoipecoside + S-Adenosyl-L-homocysteine R11682 6-O-methyldeacetylisoipecoside:beta-glucosidase; 6-O-Methyldeacetylisoipecoside + H2O <=> D-Glucose + 6-O-Methyl-N-deacetylisoipecoside aglycon R11683 6-O-Methyl-N-deacetylisoipecoside aglycon <=> Protoemetine R11684 Protoemetine + Dopamine <=> 7'-O-Demethylcephaeline + H2O R11685 S-adenosyl-L-methionine:7'-O-demethylcephaeline 7'-O-methyltransferase; 7'-O-Demethylcephaeline + S-Adenosyl-L-methionine <=> Cephaeline + S-Adenosyl-L-homocysteine R11686 S-adenosyl-L-methionine:cephaeline 6'-O-methyltransferase; Cephaeline + S-Adenosyl-L-methionine <=> Emetine + S-Adenosyl-L-homocysteine R11687 (S)-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (1-hydroxylating); (S)-cis-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-1-Hydroxy-cis-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O R11688 (S)-1-hydroxy-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (13-hydroxylating); (S)-1-Hydroxy-cis-N-methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (13S,14R)-1,13-Dihydroxy-cis-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O R11689 acetyl-CoA:(13S,14R)-1,13-dihydroxy-N-methylcanadine O-acetyltransferase; (13S,14R)-1,13-Dihydroxy-cis-N-methylcanadine + Acetyl-CoA <=> (13S,14R)-13-O-Acetyl-1-hydroxy-cis-N-methylcanadine + CoA R11690 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating); (13S,14R)-13-O-Acetyl-1-hydroxy-cis-N-methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (13S,14R)-13-O-Acetyl-1,8-dihydroxy-cis-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O R11691 (13S,14R)-13-O-Acetyl-1,8-dihydroxy-cis-N-methylcanadine <=> 4'-O-Desmethyl-3-O-acetylpapaveroxine + H+ R11692 S-adenosyl-L-methionine:3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase; 4'-O-Desmethyl-3-O-acetylpapaveroxine + S-Adenosyl-L-methionine <=> 3-O-Acetylpapaveroxine + S-Adenosyl-L-homocysteine R11693 3-O-acetylpapaveroxine acetatehydrolase; 3-O-Acetylpapaveroxine + H2O <=> Papaveroxine + Acetate R11694 4'-O-desmethyl-3-O-acetylpapaveroxine acetatehydrolase; 4'-O-Desmethyl-3-O-acetylpapaveroxine + H2O <=> 4'-O-Desmethylpapaveroxine + Acetate R11695 4'-O-Desmethylpapaveroxine <=> Narcotoline hemiacetal R11696 narcotoline hemiacetal:NAD+ 1-oxidoreductase; Narcotoline hemiacetal + NAD+ <=> Narcotoline + NADH + H+ R11697 S-adenosyl-L-methionine:3-(aminomethyl)indole N-methyltransferase (gramine-forming); 2 S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> 2 S-Adenosyl-L-homocysteine + Gramine R11698 S-adenosyl-L-methionine:3-(aminomethyl)indole N-methyltransferase; S-Adenosyl-L-methionine + 3-(Aminomethyl)indole <=> S-Adenosyl-L-homocysteine + (1H-Indol-3-yl)-N-methylmethanamine R11699 S-adenosyl-L-methionine:(1H-indol-3-yl)-N-methylmethanamine N-methyltransferase; S-Adenosyl-L-methionine + (1H-Indol-3-yl)-N-methylmethanamine <=> S-Adenosyl-L-homocysteine + Gramine R11700 S-adenosyl-L-methionine:protoheme C-methyltransferase (anaerobilin-producing); 2 S-Adenosyl-L-methionine + Heme + 2 Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + Anaerobilin + Fe2+ + 2 Oxidized flavodoxin R11701 acetyl-CoA:(3S)-3,6-diaminohexanoate N6-acetyltransferase; Acetyl-CoA + (3S)-3,6-Diaminohexanoate <=> CoA + (3S)-6-Acetamido-3-aminohexanoate R11702 GDP-alpha-D-mannose:1-phosphatidyl-1D-myo-inositol 2-alpha-D-mannosyltransferase (configuration-retaining); GDP-mannose + 1-Phosphatidyl-D-myo-inositol <=> GDP + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol R11703 GDP-alpha-D-mannose:2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol 6-alpha-D-mannosyltransferase (configuration-retaining); GDP-mannose + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol R11704 GDP-alpha-D-mannose:2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol 6-alpha-D-mannosyltransferase (configuration-retaining); GDP-mannose + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol <=> GDP + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol R11705 O-phospho-L-serine:L-glutamate N-(2S)-2-amino-2-carboxyethyltransferase; O-Phospho-L-serine + L-Glutamate <=> N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate + Orthophosphate R11706 ATP:3-dehydro-L-erythronate 4-phosphotransferase; ATP + 3-Dehydro-L-erythronate <=> ADP + 3-Dehydro-4-phospho-L-erythronate R11707 ATP:3-dehydro-D-erythronate 4-phosphotransferase; ATP:3-dehydro-L-threonate 4-phosphotransferase; ATP + 3-Dehydro-L-threonate <=> ADP + 3-Dehydro-4-phospho-D-erythronate R11708 acetyl-CoA:3-phosphonopyruvate C-acetyltransferase; Acetyl-CoA + H2O + 3-Phosphonopyruvate <=> (R)-2-(Phosphonomethyl)malate + CoA R11709 7-(Dihydroxymethyl)bacteriochlorophyllide c <=> Bacteriochlorophyllide e + H2O R11710 bacteriochlorophyllide-c:S-adenosyl-L-methionine oxidoreductase (C-7(1)-hydroxylating); 2 S-Adenosyl-L-methionine + Bacteriochlorophyllide c + H2O <=> Bacteriochlorophyllide e + 2 5'-Deoxyadenosine + 2 L-Methionine R11711 L-arginine,reduced-flavodoxin:oxygen oxidoreductase (nitric-oxide-forming); 2 L-Arginine + 3 Reduced flavodoxin + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 Oxidized flavodoxin + 4 H2O R11712 2 L-Arginine + 2 Reduced flavodoxin + 2 Oxygen <=> 2 N(omega)-Hydroxyarginine + 2 Oxidized flavodoxin + 2 H2O R11713 2 N(omega)-Hydroxyarginine + Reduced flavodoxin + 2 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + Oxidized flavodoxin + 2 H2O R11714 UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-R 3-beta-D-galactosyltransferase; UDP-alpha-D-galactose + N-Acetyl-beta-D-glucosaminide <=> UDP + 1,3-beta-D-Galactosyl-N-acetyl-D-glucosaminyl-R R11715 CMP-N-acetyl-beta-neuraminate:a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R alpha-(2->3)-N-acetylneuraminyltransferase (configuration-inverting); CMP-N-acetylneuraminate + beta-D-Galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R R11716 3-dehydro-4-phospho-L-erythronate carboxy-lyase; 3-Dehydro-4-phospho-L-erythronate <=> Glycerone phosphate + CO2 R11717 3-dehydro-4-phospho-D-erythronate carboxy-lyase; 3-Dehydro-4-phospho-D-erythronate <=> Glycerone phosphate + CO2 R11718 7,8-dihydroneopterin-3'-phosphate glycolaldehyde-phosphate-lyase [6-(hydroxymethyl)-7,8-dihydropterin-forming]; Dihydroneopterin phosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde phosphate R11719 7,8-dihydroneopterin-3'-triphosphate glycolaldehyde-phosphate-lyase [6-(hydroxymethyl)-7,8-dihydropterin-forming]; 7,8-Dihydroneopterin 3'-triphosphate <=> 6-(Hydroxymethyl)-7,8-dihydropterin + Glycolaldehyde triphosphate R11720 fructoselysine 3-epimerase; Fructoselysine <=> Psicoselysine R11721 2-dehydro-L-erythronate isomerase; 2-Dehydro-L-erythronate <=> 3-Dehydro-L-erythronate R11722 2-dehydro-D-erythronate isomerase; 2-Dehydro-D-erythronate <=> 3-Dehydro-L-threonate R11723 L-isoleucine:acetoacetyl-CoA ligase (tenuazonic acid-forming); ATP + L-Isoleucine + Acetoacetyl-CoA <=> AMP + Diphosphate + Tenuazonic acid + CoA R11724 4-phospho-D-threonate:NAD+ 3-oxidoreductase; 4-Phospho-D-threonate + NAD+ <=> Glycerone phosphate + NADH + CO2 + H+ R11726 4-phospho-D-erythronate:NAD+ 3-oxidoreductase; 4-Phospho-D-erythronate + NAD+ <=> Glycerone phosphate + CO2 + NADH + H+ R11730 (indol-3-yl)acetate,NADH:oxygen oxidoreductase (2-hydroxylating); Indole-3-acetate + NADH + H+ + Oxygen <=> (2-Hydroxy-1H-indol-3-yl)acetate + NAD+ + H2O R11731 S-adenosyl-L-methionine:(S)-norreticuline 7-O-methyltransferase; (S)-Norreticuline + S-Adenosyl-L-methionine <=> (S)-Norlaudanine + S-Adenosyl-L-homocysteine R11732 (E)-phenylacetaldehyde oxime,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Mandelonitrile + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11733 phenylacetonitrile,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase [(R)-mandelonitrile-forming]; Phenylacetonitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Mandelonitrile + [Oxidized NADPH---hemoprotein reductase] + H2O R11734 (E)-indol-3-ylacetaldoxime,[reduced NADPH---hemoprotein reductase],glutathione:oxygen oxidoreductase (oxime-hydroxylating); Indole-3-acetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11735 Indole-3-acetaldehyde oxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Indole-3-acetaldoxime N-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O R11736 Indole-3-acetaldoxime N-oxide + Glutathione <=> S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O R11737 (E)-phenylacetaldehyde oxime,[reduced NADPH---hemoprotein reductase],glutathione:oxygen oxidoreductase (oxime-hydroxylating); (E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Glutathione + Oxygen <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11738 (E)-Phenylacetaldoxime + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 1-aci-Nitro-2-phenylethane + [Oxidized NADPH---hemoprotein reductase] + H2O R11739 1-aci-Nitro-2-phenylethane + Glutathione <=> S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O R11740 (S)-Norlaudanine + S-Adenosyl-L-methionine <=> (S)-Tetrahydropapaverine + S-Adenosyl-L-homocysteine R11741 protoheme,donor:oxygen oxidoreductase (mycobilin-producing); Heme + 3 Reduced acceptor + 3 Oxygen <=> Mycobilin a + Fe2+ + 3 Acceptor + 3 H2O R11742 protoheme,donor:oxygen oxidoreductase (mycobilin-producing); Heme + 3 Reduced acceptor + 3 Oxygen <=> Mycobilin b + Fe2+ + 3 Acceptor + 3 H2O R11743 formylmethanofuran:ferredoxin oxidoreductase; Formylmethanofuran + 2 Oxidized ferredoxin + H2O <=> Methanofuran + 2 Reduced ferredoxin + CO2 + 2 H+ R11744 N-phenylhydroxylamine:NADP+ oxidoreductase; Hydroxylaminobenzene + 2 NADP+ + H2O <=> Nitrobenzene + 2 NADPH + 2 H+ R11745 cellulose,hydrogen-donor:oxygen oxidoreductase (D-glucosyl C1-hydroxylating); Cellulose(n+m) + Reduced acceptor + Oxygen <=> [(1->4)-beta-D-Glucosyl]n-(1->4)-D-glucono-1,5-lactone + Cellulose(m) + Acceptor + H2O R11747 cellulose,hydrogen-donor:oxygen oxidoreductase (D-glucosyl 4-dehydrogenating); Cellulose(n+m) + Reduced acceptor + Oxygen <=> 4-Dehydro-beta-D-glucosyl-[(1->4)-beta-D-glucosyl]n-1 + Cellulose(m) + Acceptor + H2O R11748 (S)-tetrahydropapaverine:oxygen oxidoreductase; (S)-Tetrahydropapaverine + 2 Oxygen <=> Papaverine + 2 Hydrogen peroxide R11749 trans-aconitate decarboxylase; trans-Aconitate <=> Itaconate + CO2 R11750 Itaconate <=> 2-Hydroxyparaconate R11751 Norcraugsodine + NADPH + H+ <=> Norbelladine + NADP+ R11752 Noroxopluviine <=> Caranine R11753 Caranine <=> Lycorine R11754 (4aR,10bS)-Noroxomaritidine <=> (4aR,10bS)-Normaritidine R11756 (4aR,10bS)-Noroxomaritidine <=> Elwesine R11758 (4aS,10bR)-Noroxomaritidine <=> Maritinamine R11759 (4aS,10bR)-Noroxomaritidine <=> (-)-8-Demethylmaritidine R11760 (-)-8-Demethylmaritidine <=> Vittatine R11761 Vittatine <=> Haemanthamine R11762 6-Lactoyl-5,6,7,8-tetrahydropterin <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin R11763 6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin:NADP+ oxidoreductase; 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+ R11764 tetrahydrobiopterin:NADP+ oxidoreductase [6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin-forming]; Tetrahydrobiopterin + NADP+ <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADPH + H+ R11765 tetrahydrobiopterin:NADP+ oxidoreductase (7,8-dihydrobiopterin-forming); Tetrahydrobiopterin + NADP+ <=> 7,8-Dihydrobiopterin + NADPH + H+ R11766 6-Lactoyl-5,6,7,8-tetrahydropterin <=> Sepiapterin R11767 Dihydrobiopterin <=> 7,8-Dihydrobiopterin R11768 2,5-dioxopentanoate:NAD+ 5-oxidoreductase; 2,5-Dioxopentanoate + NAD+ + H2O <=> 2-Oxoglutarate + NADH + H+ R11769 3,4-Didehydroadipyl-CoA <=> 5-Carboxy-2-pentenoyl-CoA R11770 2,4,6/3,5-Pentahydroxycyclohexanone + NAD+ <=> 3-Dehydro-scyllo-inosose + NADH + H+ R11771 3-Dehydro-scyllo-inosose + H2O <=> 5-Dehydro-L-gluconate R11772 5-Dehydro-L-gluconate <=> D-Tagaturonate R11773 propionyl-CoA:succinate CoA transferase; Propanoyl-CoA + Succinate <=> Succinyl-CoA + Propanoate R11774 (2R,3S)-2-alkyl-3-hydroxyalkanoate:NADP+ oxidoreductase; (2R,3S)-2-Alkyl-3-hydroxyalkanoate + NADP+ <=> (R)-2-Alkyl-3-oxoalkanoate + NADPH + H+ R11775 (2R,3S)-2-alkyl-3-hydroxyalkanoate ligase (beta-lactone,AMP-forming); (2R,3S)-2-Alkyl-3-hydroxyalkanoate + ATP <=> cis-3-Alkyl-4-alkyloxetan-2-one + AMP + Diphosphate R11776 (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one:NADP+ 1'-oxidoreductase; (3R,4R)-3-[(1S)-1-Hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> (3R,4R)-3-Alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+ R11777 (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine:acceptor oxidoreductase; 16-Methoxy-2,3-dihydro-3-hydroxytabersonine + Acceptor <=> (3R)-3-Hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + Reduced acceptor R11778 S-adenosyl-L-methionine:8-amino-8-demethylriboflavin N,N-dimethyltransferase; 2 S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> 2 S-Adenosyl-L-homocysteine + Roseoflavin R11779 S-adenosyl-L-methionine:8-amino-8-demethylriboflavin N-methyltransferase; S-Adenosyl-L-methionine + 8-Amino-8-demethylriboflavin <=> S-Adenosyl-L-homocysteine + 8-Demethyl-8-(methylamino)riboflavin R11780 S-adenosyl-L-methionine:8-demethyl-8-(methylamino)riboflavin N-methyltransferase; S-Adenosyl-L-methionine + 8-Demethyl-8-(methylamino)riboflavin <=> S-Adenosyl-L-homocysteine + Roseoflavin R11781 acyl-CoA:2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol acyltransferase; Acyl-CoA + 2,6-Di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol R11782 acyl-CoA:2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol acyltransferase; Acyl-CoA + 2-O-(alpha-D-Mannosyl)-1-phosphatidyl-1D-myo-inositol <=> CoA + 2-O-(6-O-Acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol R11783 ADP-alpha-D-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase (configuration-retaining); ADP-glucose + D-Glucose 6-phosphate <=> ADP + alpha,alpha'-Trehalose 6-phosphate R11784 ATP:D-threonate 4-phosphotransferase; ATP + D-Threonate <=> ADP + 4-Phospho-D-threonate R11785 N-acetyl-D-muramate 6-phosphate phosphohydrolase; N-Acetylmuramic acid 6-phosphate + H2O <=> N-Acetylmuramate + Orthophosphate R11786 (ribonucleotide)n-2',3'-cyclic phosphate 3'-nucleotidohydrolase; RNA terminal-2',3'-cyclic-phosphate + H2O <=> RNA 2'-terminal-phosphate R11787 (+)-kolavenyl-diphosphate diphosphohydrolase; (+)-Kolavenyl diphosphate + H2O <=> (+)-Kolavelool + Diphosphate R11788 1,3-alpha-isomaltohydrolase (configuration-retaining); Cyclobis-1,6-alpha-nigerosyl + 2 H2O <=> 2 Isomaltose R11789 1,3-alpha-isomaltohydrolase (configuration-retaining); Cyclobis-1,6-alpha-nigerosyl + H2O <=> alpha-Isomaltosyl-1,3-isomaltose R11790 1,3-alpha-isomaltohydrolase (configuration-retaining); alpha-Isomaltosyl-1,3-isomaltose + H2O <=> 2 Isomaltose R11791 isomaltose 6-alpha-glucohydrolase (configuration-inverting); Isomaltose + H2O <=> beta-D-Glucose + D-Glucose R11792 (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate gamma-glutamylhydrolase; (E)-1-(Glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-omega-(methylsulfanyl)alkane-1-imine + L-Glutamate R11793 S-[(E)-N-hydroxy(indol-3-yl)acetimidoyl]-L-glutathione gamma-glutamylhydrolase; S-[(E)-N-Hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + H2O <=> (E)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethane-1-imine + L-Glutamate R11794 (glutathione-S-yl)(1H-indol-3-yl)acetonitrile gamma-glutamylhydrolase; (Glutathione-S-yl)(1H-indol-3-yl)acetonitrile + H2O <=> (L-Cysteinylglycine-S-yl)(1H-indol-3-yl)acetonitrile + L-Glutamate R11795 S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione gamma-glutamylhydrolase; S-[(Z)-N-Hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O <=> (Z)-1-(L-Cysteinylglycine-S-yl)-N-hydroxy-2-phenylethane-1-imine + L-Glutamate R11796 3'-phosphoadenylyl-sulfate:12-hydroxyjasmonate sulfotransferase; 3'-Phosphoadenylyl sulfate + 12-Hydroxyjasmonate <=> Adenosine 3',5'-bisphosphate + 12-Sulfooxyjasmonate R11797 S-adenosyl-L-methionine:ornithine-lipid N-methyltransferase; 3 S-Adenosyl-L-methionine + Ornithine lipid <=> 3 S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid R11798 S-adenosyl-L-methionine:ornithine-lipid N-methyltransferase; S-Adenosyl-L-methionine + Ornithine lipid <=> S-Adenosyl-L-homocysteine + N-Methylornithine lipid R11799 S-adenosyl-L-methionine:N-methylornithine-lipid N-methyltransferase; S-Adenosyl-L-methionine + N-Methylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid R11800 S-adenosyl-L-methionine:N,N-dimethylornithine-lipid N-methyltransferase; S-Adenosyl-L-methionine + N,N-Dimethylornithine lipid <=> S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid R11801 L-ornithine Nalpha-(3R)-3-hydroxy-acyltransferase; L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> Lyso-ornithine lipid + Acyl-carrier protein R11802 (3R)-3-hydroxy-2,3-dihydrotabersonine:acceptor oxidoreductase; (3R)-3-Hydroxy-2,3-dihydrotabersonine + Acceptor <=> (3R)-3-Hydroxy-1,2-didehydro-2,3-dihydrotabersonine + Reduced acceptor R11803 ATP:D-erythronate 4-phosphotransferase; ATP + D-Erythronate <=> ADP + 4-Phospho-D-erythronate R11804 omega-(methylthio)alkyl-glucosinolate,NADPH:oxygen S-oxidoreductase; omega-(Methylthio)alkyl-glucosinolate + NADPH + H+ + Oxygen <=> omega-(Methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O R11805 dimethylamine,NADPH:oxygen oxidoreductase (formaldehyde-forming); Dimethylamine + NADPH + H+ + Oxygen <=> Methylamine + Formaldehyde + NADP+ + H2O R11806 jasmonoyl-L-amino acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Jasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxyjasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + H2O R11807 12-hydroxyjasmonoyl-L-amino acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); 12-Hydroxyjasmonoyl-L-amino acid + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 12-Hydroxy-12-oxojasmonoyl-L-amino acid + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R11808 12-Hydroxyjasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11809 12-Oxojasmonoyl-L-amino acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 12-Hydroxy-12-oxojasmonoyl-L-amino acid + [Oxidized NADPH---hemoprotein reductase] + H2O R11810 16-methoxytabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); 16-Methoxytabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3R)-3-Hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O R11811 tabersonine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating); Tabersonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3R)-3-Hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [Oxidized NADPH---hemoprotein reductase] + H2O R11812 butachlor,ferredoxin:oxygen oxidoreductase (butyl formate-releasing); Butachlor + 2 Reduced ferredoxin + Oxygen <=> 2-Chloro-N-(2,6-diethylphenyl)acetamide + Butyl formate + 2 Oxidized ferredoxin + H2O R11813 2-(cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (camalexin-forming); 2-(L-Cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Camalexin + Hydrogen cyanide + CO2 + 2 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R11814 2-(L-Cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (R)-Dihydrocamalexate + Hydrogen cyanide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11815 (R)-Dihydrocamalexate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Camalexin + CO2 + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11816 protoheme,donor:oxygen oxidoreductase (biliverdin-IX-delta-forming); Heme + 3 Reduced acceptor + 3 Oxygen <=> Biliverdin-IX-delta + CO + Fe2+ + 3 Acceptor + 3 H2O R11817 protoheme,donor:oxygen oxidoreductase (biliverdin-IX-beta-forming); Heme + 3 Reduced acceptor + 3 Oxygen <=> Biliverdin-IX-beta + CO + Fe2+ + 3 Acceptor + 3 H2O R11818 formate:NAD+, ferredoxin oxidoreductase; 2 Formate + NAD+ + 2 Oxidized ferredoxin <=> 2 CO2 + NADH + H+ + 2 Reduced ferredoxin R11819 trans-4-hydroxy-L-proline hydro-lyase; Hydroxyproline <=> (S)-1-Pyrroline-5-carboxylate + H2O R11820 geranylgeranyl-diphosphate hydratase (ent-8alpha-hydroxylabd-13-en-15-yl-diphosphate-forming); ent-8alpha-hydroxylabd-13-en-15-yl-diphosphate hydro-lyase; ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> Geranylgeranyl diphosphate + H2O R11821 geranylgeranyl-diphosphate hydratase (peregrinol-diphosphate-forming); peregrinol-diphosphate hydro-lyase; Peregrinol diphosphate <=> Geranylgeranyl diphosphate + H2O R11822 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-isoafricanol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-Isoafricanol + Diphosphate R11823 geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, (-)-spiroviolene-forming]; Geranylgeranyl diphosphate <=> (-)-Spiroviolene + Diphosphate R11824 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, tsukubadiene-forming); Geranylgeranyl diphosphate <=> Tsukubadiene + Diphosphate R11825 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (2S,3R,6S,9S)-(-)-protoillud-7-ene-forming]; trans,trans-Farnesyl diphosphate <=> (2S,3R,6S,9S)-(-)-Protoillud-7-ene + Diphosphate R11826 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (3S)-(+)-asterisca-2(9),6-diene-forming]; trans,trans-Farnesyl diphosphate <=> (3S)-(+)-Asterisca-2(9),6-diene + Diphosphate R11827 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-amorphene-forming]; trans,trans-Farnesyl diphosphate <=> (-)-alpha-Amorphene + Diphosphate R11828 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-corvol-ether-B-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether B + Diphosphate R11829 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-eremophilene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-Eremophilene + Diphosphate R11830 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (1R,4R,5S)-(-)-guaia-6,10(14)-diene-forming]; trans,trans-Farnesyl diphosphate <=> (1R,4R,5S)-(-)-Guaia-6,10(14)-diene + Diphosphate R11831 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-(1E,4E,6S,7R)-germacra-1(10),4-dien-6-ol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-(1E,4E,6S,7R)-Germacra-1(10),4-dien-6-ol + Diphosphate R11832 geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, (3E,7E)-dolabella-3,7-dien-18-ol-forming]; Geranylgeranyl diphosphate + H2O <=> (3E,7E)-Dolabella-3,7-dien-18-ol + Diphosphate R11833 geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, (3E,7E)-dolathalia-3,7,11-triene-forming]; Geranylgeranyl diphosphate <=> (3E,7E)-Dolathalia-3,7,11-triene + Diphosphate R11834 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-alpha-eudesmol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 7-epi-alpha-Eudesmol + Diphosphate R11835 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 4-epi-cubebol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 4-epi-Cubebol + Diphosphate R11836 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-corvol-ether-A-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-Corvol ether A + Diphosphate R11837 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 10-epi-juneol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Juneol + Diphosphate R11838 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, tau-cadinol-forming); trans,trans-Farnesyl diphosphate + H2O <=> tau-Cadinol + Diphosphate R11839 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (2E,6E)-hedycaryol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (2E,6E)-Hedycaryol + Diphosphate R11840 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 10-epi-cubebol-forming); trans,trans-Farnesyl diphosphate + H2O <=> 10-epi-Cubebol + Diphosphate R11841 all-trans-pentaprenyl-diphosphate diphosphate-lyase (cyclizing, sesterfisherol-forming); all-trans-Pentaprenyl diphosphate + H2O <=> Sesterfisherol + Diphosphate R11842 geranyl-diphosphate diphosphate-lyase (cyclizing, beta-thujene-forming); Geranyl diphosphate <=> beta-Thujene + Diphosphate R11843 all-trans-pentaprenyl-diphosphate diphosphate-lyase (cylizing, stellata-2,6,19-triene-forming); all-trans-Pentaprenyl diphosphate <=> Stellata-2,6,19-triene + Diphosphate R11844 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, guaia-4,6-diene-forming); trans,trans-Farnesyl diphosphate <=> Guaia-4,6-diene + Diphosphate R11845 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, pseudolaradiene-forming); Geranylgeranyl diphosphate <=> Pseudolaratriene + Diphosphate R11846 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, selina-4(15),7(11)-diene-forming); trans,trans-Farnesyl diphosphate <=> Selina-4(15),7(11)-diene + Diphosphate R11847 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-(2S,3R,9R)-pristinol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-(2S,3R,9R)-Pristinol + Diphosphate R11848 (+)-copalyl-diphosphate diphosphate-lyase (cyclizing, nezukol-forming); Copalyl diphosphate + H2O <=> Nezukol + Diphosphate R11849 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 5-hydroxy-alpha-gurjunene-forming); trans,trans-Farnesyl diphosphate + H2O <=> 5-Hydroxy-alpha-gurjunene + Diphosphate R11850 ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-atiserine-forming); ent-Copalyl diphosphate <=> ent-Atiserene + Diphosphate R11851 ent-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (cyclizing, ent-13-epi-manoyl-oxide-forming); ent-8alpha-Hydroxylabd-13-en-15-yl diphosphate <=> ent-13-epi-Manoyl oxide + Diphosphate R11852 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (2Z,6E)-hedycaryol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (2Z,6E)-Hedycaryol + Diphosphate R11853 all-trans-pentaprenyl-diphosphate diphosphate-lyase (beta-geranylfarnesene-forming); all-trans-Pentaprenyl diphosphate <=> beta-Geranylfarnesene + Diphosphate R11854 all-trans-hexaprenyl-diphosphate diphosphate-lyase (beta-hexaprene-forming); all-trans-Hexaprenyl diphosphate <=> beta-Hexaprene + Diphosphate R11855 all-trans-heptaprenyl-diphosphate diphosphate-lyase (beta-heptaprene-forming); all-trans-Heptaprenyl diphosphate <=> beta-Heptaprene + Diphosphate R11856 peregrinol-diphosphate diphosphate-lyase [(13R)-9,13-epoxylabd-14-ene-forming]; Peregrinol diphosphate <=> (13R)-9,13-Epoxylabd-14-ene + Diphosphate R11857 (13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate diphosphate-lyase (manoyl-oxide-forming); copal-8-ol-diphosphate diphosphate-lyase (manoyl-oxide-forming); Copal-8-ol diphosphate <=> Manoyl oxide + Diphosphate R11858 geranylgeranyl-diphosphate diphosphate-lyase (cycloaraneosene-forming); Geranylgeranyl diphosphate <=> Cycloaraneosene + Diphosphate R11859 (13E)-labda-7,13-dien-15-yl-diphosphate diphosphate-lyase [labda-7,13(16),14-triene-forming]; (13E)-Labda-7,13-dien-15-yl diphosphate <=> Labda-7,13(16),14-triene + Diphosphate R11860 (+)-copalyl-diphosphate diphosphate-lyase [(12E)-labda-8(17),12,14-triene-forming]; Copalyl diphosphate <=> (12E)-Labda-8(17),12,14-triene + Diphosphate R11861 glutathione gamma-glutamyl cyclotransferase (5-oxoproline-forming); Glutathione <=> Cys-Gly + 5-Oxoproline R11862 epsilon-(gamma-L-glutamyl)-L-lysine gamma-glutamyl cyclotransferase (5-oxoproline-forming); epsilon-(gamma-L-Glutamyl)-L-lysine <=> L-Lysine + 5-Oxoproline R11864 S-(Hercyn-2-yl)-L-cysteine S-oxide + H2O <=> 2-(Hydroxysulfanyl)hercynine + Pyruvate + Ammonia R11865 2-(Hydroxysulfanyl)hercynine + Reduced acceptor <=> Ergothioneine + Acceptor + H2O R11866 (RS)-linalool hydroxymutase; Linalool <=> Geraniol R11867 (3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene mutase (cyclizing, pre-alpha-onocerin-forming); (3S,22S)-2,3:22,23-Diepoxy-2,3,22,23-tetrahydrosqualene <=> Pre-alpha-onocerin R11868 pre-alpha-onocerin mutase (cyclizing, alpha-onocerin-forming); Pre-alpha-onocerin <=> alpha-Onocerin R11869 (-)-kolavenyl-diphosphate lyase (ring-opening); Geranylgeranyl diphosphate <=> (-)-Kolavenyl diphosphate R11870 (+)-kolavenyl-diphosphate lyase (ring-opening); Geranylgeranyl diphosphate <=> (+)-Kolavenyl diphosphate R11871 (13E)-labda-7,13-dien-15-yl-diphosphate lyase (ring-opening); Geranylgeranyl diphosphate <=> (13E)-Labda-7,13-dien-15-yl diphosphate R11872 4-hydroxybenzoate:[acyl-carrier protein] ligase (AMP-forming); ATP + 4-Hydroxybenzoate + Acyl-carrier protein <=> AMP + Diphosphate + 4-Hydroxybenzoyl-[acp] R11873 4-Hydroxybenzoyl-adenylate + Acyl-carrier protein <=> AMP + 4-Hydroxybenzoyl-[acp] R11874 reduced coenzyme F420:methanophenazine oxidoreductase; Reduced coenzyme F420 + Methanophenazine <=> Coenzyme F420 + Dihydromethanophenazine R11875 L-carnitine,NADH:oxygen oxidoreductase (trimethylamine-forming); L-Carnitine + NADH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NAD+ + H2O R11876 4-sulfanylbutanoate:NAD+ oxidoreductase; 2 4-Sulfanylbutanoate + NAD+ <=> 4,4'-Disulfanediyldibutanoate + NADH + H+ R11877 (3R)-2'-hydroxyisoflavanone:NADP+ 4-oxidoreductase; (4R)-4,2'-Dihydroxyisoflavan + NADP+ <=> (3R)-2'-Hydroxyisoflavanone + NADPH + H+ R11878 [sulfatase]-L-cysteine:oxygen oxidoreductase (3-oxo-L-alanine-forming); [Sulfatase]-L-cysteine + Oxygen + 2 Thiol <=> [Sulfatase]-3-oxo-L-alanine + Hydrogen sulfide + Oxidized thiol-containing reductant + H2O R11879 UDP-N-acetyl-alpha-D-glucosamine:beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-R 6-beta-N-acetylglucosaminyltransferase (configuration-inverting); UDP-N-acetyl-alpha-D-glucosamine + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-R <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R R11880 manganese(II):oxygen oxidoreductase; 4 Manganese(2+) + 2 Oxygen + 4 H2O <=> 4 Mn(IV)O2 + 8 H+ R11881 4 Manganese(2+) + Oxygen + 4 H+ <=> 4 Manganese(3+) + 2 H2O R11882 4 Manganese(3+) + Oxygen + 6 H2O <=> 4 Mn(IV)O2 + 12 H+ R11885 2 Ubiquinol <=> 2 Ubiquinone + 4 H+ + 4 e- R11886 Oxygen + 4 H+ + 4 e- <=> 2 H2O R11887 3'-phosphoadenylyl-sulfate:7-methylthioheptyl-desulfoglucosinolate sulfotransferase; 3'-Phosphoadenylyl sulfate + 7-Methylthioheptyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 7-Methylthioheptyl glucosinolate R11888 3'-phosphoadenylyl-sulfate:8-methylthiooctyl-desulfoglucosinolate sulfotransferase; 3'-Phosphoadenylyl sulfate + 8-Methylthiooctyl-desulfoglucosinolate <=> Adenosine 3',5'-bisphosphate + 8-Methylthiooctyl glucosinolate R11889 N,N'-diacetylchitobiose acetylhydrolase; Chitobiose + H2O <=> N-Acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + Acetate R11890 Carmofur <=> 5-FU R11891 ATP:5-fluorouridine-monophosphate phosphotransferase; ATP + 5-Fluorouridine monophosphate <=> ADP + 5-Fluorouridine diphosphate R11892 ATP:5-fluorodeoxyuridine-monophosphate phosphotransferase; ATP + 5-Fluorodeoxyuridine monophosphate <=> ADP + 5-Fluorodeoxyuridine diphosphate R11893 5-fluorodeoxyuridine-diphosphate:thioredoxin-disulfide 2'-oxidoreductase; 5-Fluorodeoxyuridine diphosphate + Thioredoxin disulfide + H2O <=> 5-Fluorouridine diphosphate + Thioredoxin R11894 ATP:5-fluorouridine-diphosphate phosphotransferase; ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate R11895 ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase; ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate R11896 5-fluorodeoxyuridine-triphosphate diphosphohydrolase; 5-Fluorodeoxyuridine triphosphate + H2O <=> 5-Fluorodeoxyuridine monophosphate + Diphosphate R11897 2-hydroxyethyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming); Ethylene oxide + Coenzyme M <=> 2-Hydroxyethyl-CoM R11898 2-Hydroxyethyl-CoM <=> Acetyl-CoA R11899 2-chloro-2-hydroxyethyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming); Chloroethylene oxide + Coenzyme M <=> 2-Chloro-2-hydroxyethyl-CoM R11900 2-Chloro-2-hydroxyethyl-CoM <=> Acetyl-CoA R11901 chloroethylene,NADH:oxygen oxidoreductase; Vinyl chloride + NADH + H+ + Oxygen <=> Chloroethylene oxide + NAD+ + H2O R11902 acetyl-CoA:hydrazine N-acetyltransferase; Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine R11903 acetylhydrazine amidohydrolase; Acetylhydrazine + H2O <=> Hydrazine + Acetate R11904 acetylhydrazine,NADPH:oxygen oxidoreductase; Acetylhydrazine + NADPH + H+ + Oxygen <=> Hepatotoxins + NADP+ + H2O R11905 Hepatotoxins + Glutathione <=> R-S-Glutathione R11906 isoniazid:hydrogen-peroxide oxidoreductase; Isoniazid + Hydrogen peroxide <=> Isonicotinoyl radical + Diimine + 2 H2O R11907 Isonicotinoyl radical + NAD+ <=> Isonicotinoyl-NAD adduct R11909 Isonicotinoyl radical + NADP+ <=> Isonicotinoyl-NADP adduct R11911 L-carnitine,NADPH:oxygen oxidoreductase (trimethylamine-forming); L-Carnitine + NADPH + H+ + Oxygen <=> (3R)-3-Hydroxy-4-oxobutanoate + Trimethylamine + NADP+ + H2O R11912 tryptamine,hydrogen-donor:oxygen oxidoreductase (4-hydroxylating); Tryptamine + Reduced acceptor + Oxygen <=> 4-Hydroxytryptamine + Acceptor + H2O R11913 4,4'-diapolycopen-4-al,donor:oxygen oxidoreductase (4,4'-diapolycopen-4-oate-forming); 4,4'-Diapolycopen-4-al + H2O + Acceptor <=> 4,4'-Diapolycopen-4-oate + Reduced acceptor R11914 4,4'-diapolycopene-4,4'-dial,donor:oxygen oxidoreductase (4,4'-diapolycopene-4,4'-dioate-forming); 4,4'-Diapolycopenedial + 2 H2O + 2 Acceptor <=> 4,4'-Diapolycopene-4,4'-dioate + 2 Reduced acceptor R11915 fatty acid carboxy-lyase (light-dependent, alkane-forming); Long-chain fatty acid + hn <=> Long-chain alkane + CO2 R11916 L-dopa carboxy-lyase (oxidative-deaminating); 3,4-Dihydroxy-L-phenylalanine + Oxygen + H2O <=> 3,4-Dihydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide R11917 L-tyrosine carboxy-lyase (oxidative-deaminating); L-Tyrosine + Oxygen + H2O <=> 4-Hydroxyphenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide R11918 L-phenylalanine carboxy-lyase (oxidative-deaminating); L-Phenylalanine + Oxygen + H2O <=> Phenylacetaldehyde + CO2 + Ammonia + Hydrogen peroxide R11919 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole formate-lyase (5-hydroxybenzimidazole-forming); Aminoimidazole ribotide + S-Adenosyl-L-methionine + Reduced acceptor <=> 5-Hydroxybenzimidazole + 5'-Deoxyadenosine + L-Methionine + Formate + Ammonia + Orthophosphate + Acceptor R11920 geranygeranyl-diphosphate diphosphate-lyase (rhizathalene-A-forming); Geranylgeranyl diphosphate <=> Rhizathalene A + Diphosphate R11921 Ni(II)-pyridinium-3,5-bisthiocarboxylate-mononucleotide nickel-lyase (pyridinium-3,5-bisthiocarboxylate-mononucleotide forming); Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide <=> Pyridinium-3,5-bisthiocarboxylate mononucleotide + Nickel(2+) R11922 17-(4-hydroxyphenyl)heptadecanoate:[acyl-carrier protein] ligase (AMP-forming); ATP + 17-(4-Hydroxyphenyl)heptadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] R11923 17-(4-Hydroxyphenyl)heptadecanoyl adenylate + Acyl-carrier protein <=> AMP + 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] R11924 19-(4-hydroxyphenyl)nonadecanoate:[acyl-carrier protein] ligase (AMP-forming); ATP + 19-(4-Hydroxyphenyl)nonadecanoate + Acyl-carrier protein <=> AMP + Diphosphate + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] R11925 19-(4-Hydroxyphenyl)nonadecanoyl adenylate + Acyl-carrier protein <=> AMP + 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] R11926 (R)-4,5-dihydro-2-(6-hydroxy-1,3-benzothiazol-2-yl)thiazole-4-carboxylate:CoA ligase (AMP-forming); ATP + L-Firefly luciferin + CoA <=> AMP + Diphosphate + L-Firefly luciferyl-CoA R11927 [(3S)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate:NADP+ oxidoreductase; [(3S,4R)-4-Alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP+ <=> (4-Alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + NADPH + H+ R11928 CoB,CoM,ferredoxin:coenzyme F420 oxidoreductase; Coenzyme B + Coenzyme M + 2 Coenzyme F420 + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Reduced coenzyme F420 + 2 Oxidized ferredoxin R11929 sulfide:glutathione,quinone oxidoreductase; Hydrogen sulfide + Glutathione + Quinone <=> S-Sulfanylglutathione + Hydroquinone R11930 1-(4-Methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O <=> 2-({[(4-Methoxyphenyl)methyl](methyl)amino}methyl)-2-methylpropane-1,3-diol R11931 CoB,CoM:ferredoxin oxidoreductase; Coenzyme B + Coenzyme M + 2 Oxidized ferredoxin <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Reduced ferredoxin + 2 H+ R11932 4-hydroxy-L-tryptophan carboxy-lyase; 4-Hydroxy-L-tryptophan <=> 4-Hydroxytryptamine + CO2 R11933 ATP:4-hydroxytryptamine 4-phosphotransferase; ATP + 4-Hydroxytryptamine <=> ADP + Norbaeocystin R11934 S-adenosyl-L-methionine:norbaeocystin N,N-dimethyltransferase; S-adenosyl-L-methionine:4-hydroxytryptamine-4-phosphate N,N-dimethyltransferase; 2 S-Adenosyl-L-methionine + Norbaeocystin <=> 2 S-Adenosyl-L-homocysteine + Psilocybin R11935 S-adenosyl-L-methionine:norbaeocystin N-methyltransferase; S-Adenosyl-L-methionine + Norbaeocystin <=> S-Adenosyl-L-homocysteine + Baeocystin R11936 S-adenosyl-L-methionine:baeocystin N-methyltransferase; S-Adenosyl-L-methionine + Baeocystin <=> S-Adenosyl-L-homocysteine + Psilocybin R11937 GDP-alpha-D-mannose:N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase (configuration-retaining); GDP-mannose + N-Acetyl-D-glucosaminyldiphosphoundecaprenol <=> GDP + alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11938 GDP-alpha-D-mannose:alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase (configuration-retaining); 2 GDP-mannose + alpha-D-Mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + alpha-D-Mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R11939 UDP-alpha-D-glucose:mogrol 3-O-glucosyltransferase; UDP-glucose + Mogrol <=> Mogroside IE + UDP R11940 dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 3 isopentenyl units); Dimethylallyl diphosphate + 3 Isopentenyl diphosphate <=> 3 Diphosphate + Nerylneryl diphosphate R11941 ATP:L-glutamine N5-phosphotransferase; ATP + L-Glutamine + H2O <=> AMP + Orthophosphate + N5-Phospho-L-glutamine R11942 oleuropein 2-beta-D-glucohydrolase; Oleuropein + H2O <=> Oleuropein aglycone + D-Glucose R11943 CoB,CoM,ferredoxin:H2 oxidoreductase; Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Hydrogen R11944 coenzyme B,coenzyme M,ferredoxin:formate oxidoreductase; Coenzyme B + Coenzyme M + 2 Reduced ferredoxin + 2 CO2 + 2 H+ <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + 2 Oxidized ferredoxin + 2 Formate R11945 NADH:ubiquinone oxidoreductase; Ubiquinone + NADH + H+ + 4 H+ <=> Ubiquinol + NAD+ + 4 H+ R11946 S-Sulfanylglutathione + Oxygen <=> S-Sulfinatoglutathione R11947 S-Sulfinatoglutathione + H2O <=> Glutathione + Sulfite R11948 ornithine lipid,2-oxoglutarate:oxygen oxidoreductase (ester-linked acyl 2-hydroxylase); Ornithine lipid + 2-Oxoglutarate + Oxygen <=> 2-Hydroxyornithine lipid + Succinate + CO2 R11949 (3S,6E)-nerolidol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Nerolidol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (3E)-4,8-Dimethylnona-1,3,7-triene + But-3-en-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11950 jasmonate:L-amino-acid ligase; ATP + (-)-Jasmonic acid + L-Amino acid <=> AMP + Diphosphate + Jasmonoyl-L-amino acid R11951 ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-hydroxyferruginol forming); Ferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxyferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O R11952 all-trans-retinol,reduced adrenodoxin:oxygen 3,4-oxidoreductase; Retinol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> all-trans-3,4-Didehydroretinol + 2 Oxidized adrenal ferredoxin + 2 H2O R11953 S-adenosyl-L-methionine:adenine in U6 snRNA methyltransferase; S-Adenosyl-L-methionine + Adenine in U6 snRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in U6 snRNA R11954 S-adenosyl-L-methionine:(+)-kolavelool O-methyltransferase; S-Adenosyl-L-methionine + (+)-Kolavelool <=> S-Adenosyl-L-homocysteine + (+)-O-Methylkolavelool R11955 (+)-sesamin:tetrahydrofolate N-methylenetransferase; Sesamin + Tetrahydrofolate <=> (+)-Demethylpiperitol + 5,10-Methylenetetrahydrofolate R11956 (+)-demethylpiperitol:tetrahydrofolate N-methylenetransferase; (+)-Demethylpiperitol + Tetrahydrofolate <=> (+)-Didemethylpinoresinol + 5,10-Methylenetetrahydrofolate R11957 acetyl-CoA:ethanol O-acetyltransferase; Acetyl-CoA + Ethanol <=> CoA + Ethyl acetate R11958 acyl-CoA:acyl-CoA alkyltransferase [(2R)-2-alkyl-3-oxoalkanoate-forming]; 2 Acyl-CoA + H2O <=> (R)-2-Alkyl-3-oxoalkanoate + 2 CoA R11959 2-O-(alpha-D-glucopyranosyl)-D-glycerate:phosphate alpha-D-glucosyltransferase (configuration-retaining); 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + Orthophosphate <=> D-Glucose 1-phosphate + D-Glycerate R11960 L-glutamate:FMN aminotransferase (oxidizing, decarboxylating); L-Glutamate + FMN + Oxygen + H2O + 3 Acceptor <=> 2-Oxoglutarate + 8-Amino-8-demethylriboflavin 5'-phosphate + CO2 + 3 Reduced acceptor R11961 FMN + Oxygen <=> 8-Demethyl-8-formylriboflavin 5'-phosphate + H2O R11962 8-Demethyl-8-formylriboflavin 5'-phosphate + H2O + Acceptor <=> 8-Carboxy-8-demethylriboflavin 5'-phosphate + Reduced acceptor R11963 L-Glutamate + 8-Carboxy-8-demethylriboflavin 5'-phosphate + H2O + 2 Acceptor <=> 2-Oxoglutarate + 8-Amino-8-demethylriboflavin 5'-phosphate + CO2 + 2 Reduced acceptor R11964 ATP:rifampicin, water 21-O-phosphotransferase; ATP + Rifampicin + H2O <=> AMP + 21-Phosphorifampicin + Orthophosphate R11965 teichoic acid D-alanylhydrolase; Wall teichoic acid + n H2O <=> Wall teichoic acid + n D-Alanine R11971 [SoxY protein]-S-disulfanyl-L-cysteine:cytochrome-c oxidoreductase; [SoxY protein]-S-disulfanyl-L-cysteine + 6 Ferricytochrome c + 3 H2O <=> [SoxY protein]-S-sulfosulfanyl-L-cysteine + 6 Ferrocytochrome c + 6 H+ R11972 UDP-beta-L-rhamnose:rhamnogalacturonan I 4-rhamnosyltransferase (configuration-inverting); UDP-L-rhamnose + alpha-D-Galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n <=> UDP + [(1->2)-alpha-L-Rhamnosyl-(1->4)-alpha-D-galacturonosyl]n R11973 11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; 11-Hydroxyferruginol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Carnosic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R11974 ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (salviol forming); Ferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Salviol + [Oxidized NADPH---hemoprotein reductase] + H2O R11975 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (maniladiol forming); beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Maniladiol + [Oxidized NADPH---hemoprotein reductase] + H2O R11976 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (daturadiol forming); beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Daturadiol + [Oxidized NADPH---hemoprotein reductase] + H2O R11977 ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sugiol forming); Ferruginol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Sugiol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R11978 ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; ent-2alpha-Hydroxyisokaurene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + H2O + [Oxidized NADPH---hemoprotein reductase] R11979 11-hydroxysugiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxysugiol forming); 11-Hydroxysugiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11,20-Dihydroxysugiol + [Oxidized NADPH---hemoprotein reductase] + H2O R11980 9beta-pimara7,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9beta-pimara-7,15-diene-3beta-ol forming); 9beta-Pimara-7,15-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 9beta-Pimara-7,15-diene-3beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R11981 ent-cassa-12,15-diene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ent-3beta-hydroxycassa-12,15-dien-2-one forming); ent-Cassa-12,15-diene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R11982 ent-Cassa-12,15-diene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2beta-ol + [Oxidized NADPH---hemoprotein reductase] + H2O R11983 ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11984 ent-Cassa-12,15-dien-2-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + H2O R11985 ent-Cassa-12,15-dien-2beta-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-Cassa-12,15-diene-2beta,3beta-diol + [Oxidized NADPH---hemoprotein reductase] + H2O R11986 ent-Cassa-12,15-diene-2beta,3beta-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> ent-3beta-Hydroxycassa-12,15-dien-2-one + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R11987 11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxyferruginol forming); 11-Hydroxyferruginol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11,20-Dihydroxyferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O R11988 sugiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-hydroxysugiol forming); Sugiol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxysugiol + [Oxidized NADPH---hemoprotein reductase] + H2O R11989 ferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Ferruginol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Pisiferic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R11990 11-hydroxyferruginol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-hydroxysugiol forming); 11-Hydroxyferruginol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Hydroxysugiol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R11991 (2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen <=> (4S)- 2,3-Dehydroflavan-3,4-diol + Succinate + CO2 + H2O R11992 (4S)- 2,3-Dehydroflavan-3,4-diol + H+ <=> Anthocyanidin with a 3-hydroxy group + H2O R11993 (2R,3S,4S)-leucoanthocyanidin,2-oxoglutarate:oxygen oxidoreductase; (2R,3S,4S)-Leucoanthocyanidin + 2-Oxoglutarate + Oxygen + H+ <=> Anthocyanidin with a 3-hydroxy group + Succinate + CO2 + 2 H2O R11994 GDP-D-mannose + Triacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Triacylated phosphatidyl-myo-inositol trimannoside R11995 GDP-D-mannose + Tetraacylated phosphatidyl-myo-inositol dimannoside <=> GDP + Tetraacylated phosphatidyl-myo-inositol trimannoside R11996 (S)-lactate:oxygen 2-oxidoreductase; (S)-Lactate + Oxygen <=> Pyruvate + Hydrogen peroxide R11997 beta-D-Mannosylphosphodecaprenol + Triacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Triacylated phosphatidyl-myo-inositol pentamannoside R11998 beta-D-Mannosylphosphodecaprenol + Tetraacylated phosphatidyl-myo-inositol tetramannoside <=> Decaprenol phosphate + Tetraacylated phosphatidyl-myo-inositol pentamannoside R11999 cis-1,4-polyisoprene:oxygen dioxygenase [(4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal-forming]; cis-1,4-Polyisoprene + n Oxygen <=> n (4Z,8Z)-4,8-Dimethyl-12-oxotrideca-4,8-dienal R12000 siroheme carboxy-lyase; Siroheme <=> 12,18-Didecarboxysiroheme + 2 CO2 R12001 12,18-Didecarboxysiroheme <=> Fe-coproporphyrin III R12002 Fe-coproporphyrin III:S-adenosyl-L-methionine oxidoreductase (decarboxylating); Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine <=> Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine R12003 lutein Delta4-Delta5-isomerase; Lutein <=> meso-Zeaxanthin R12004 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole cyclase (hapalindole H-forming); 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> Hapalindole H R12005 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole cyclase (12-epi-hapalindole U-forming); 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Hapalindole U R12006 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole cyclase (12-epi-fischerindole U-forming); 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-Fischerindole U R12007 cucurbitadienol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (11-oxocucurbitadienol forming); Cucurbitadienol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 11-Oxocucurbitadienol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R12008 Cucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Hydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O R12009 11-Hydroxycucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Oxocucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12010 drimenol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (drimendiol forming); (-)-Drimenol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Drimendiol + [Oxidized NADPH---hemoprotein reductase] + H2O R12011 S-adenosyl-L-methionine:adenine in mRNA methyltransferase; S-Adenosyl-L-methionine + Adenine in mRNA <=> S-Adenosyl-L-homocysteine + N6-Methyladenine in mRNA R12012 GDP-6-deoxy-alpha-D-altrose:sordaricin 6-deoxy-D-altrosyltransferase; GDP-6-deoxy-alpha-D-altrose + Sordaricin <=> 4'-O-Demethylsordarin + GDP R12013 4-hydroxybenzoate:NADPH oxidoreductase (brominating, decarboxylating); 4-Hydroxybenzoate + 2 NADPH + 2 Bromide + 2 Oxygen + 4 H+ <=> 2,4-Dibromophenol + 2 NADP+ + CO2 + 4 H2O R12014 UDP-N-acetyl-alpha-D-glucosamine:4-O-(D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol beta-N-acetyl-D-glucosaminyltransferase (configuration-inverting); n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(2-N-Acetyl-beta-D-glucosaminyl-D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12015 4-Hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4-hydroxybenzoate + NADP+ + 2 H2O R12016 3-Bromo-4-hydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 2,4-Dibromophenol + NADP+ + CO2 + 2 H2O R12017 deamido-NAD+:hydrogencarbonate nicotinate-beta-D-ribonucleotidyltransferase; Deamino-NAD+ + HCO3- <=> AMP + Pyridinium-3,5-biscarboxylic acid mononucleotide R12018 3,4-dihydroxybenzoate:NADPH oxidoreductase (brominating, decarboxylating); 3,4-Dihydroxybenzoate + 2 NADPH + 2 Bromide + 2 Oxygen + 4 H+ <=> 3,5-Dibromobenzene-1,2-diol + 2 NADP+ + CO2 + 4 H2O R12019 3,4-Dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3-Bromo-4,5-dihydroxybenzoate + NADP+ + 2 H2O R12020 3-Bromo-4,5-dihydroxybenzoate + NADPH + Bromide + Oxygen + 2 H+ <=> 3,5-Dibromobenzene-1,2-diol + NADP+ + CO2 + 2 H2O R12021 Pyrrole-2-carbonyl-[pcp] + FADH2 + Cl- + Oxygen <=> 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O R12022 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Cl- + Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O R12023 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein]:FADH2 oxidoreductase (chlorinating); Pyrrole-2-carbonyl-[pcp] + 2 FADH2 + 2 Cl- + 2 Oxygen <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + 2 FAD + 4 H2O R12024 N-(4-oxoglutaryl)-L-cysteinylglycine amidohydrolase; N-(4-Oxoglutaryl)-L-cysteinylglycine + H2O <=> 2-Oxoglutarate + Cys-Gly R12025 cis-3-[2,2-Dichloro-1-(4-chlorophenyl)vinyl]-6-chlorocyclohexa-3,5-diene-1,2-diol + NAD+ <=> 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene + NADH + H+ R12026 NAD+:glycine ADP-D-ribosyltransferase (sulfide-adding); NAD+ + Glycine + Hydrogen sulfide <=> Nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O R12027 Pyrrole-2-carbonyl-[pcp] + FADH2 + Bromide + Oxygen <=> 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O R12028 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O R12029 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FADH2 + Bromide + Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + FAD + 2 H2O R12030 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein]:FADH2 oxidoreductase (brominating); Pyrrole-2-carbonyl-[pcp] + 3 FADH2 + 3 Bromide + 3 Oxygen <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + 3 FAD + 6 H2O R12031 L-tryptophan:FADH2 oxidoreductase (5-halogenating); L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 5-Chloro-L-tryptophan + FAD + 2 H2O R12032 L-tryptophan:FADH2 oxidoreductase (6-halogenating); L-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-L-tryptophan + FAD + 2 H2O R12033 D-tryptophan:FADH2 oxidoreductase (6-halogenating); D-Tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6-Chloro-D-tryptophan + FAD + 2 H2O R12034 7-chloro-L-tryptophan:FADH2 oxidoreductase (6-halogenating); 7-Chloro-L-tryptophan + FADH2 + Cl- + Oxygen + H+ <=> 6,7-Dichloro-L-tryptophan + FAD + 2 H2O R12035 N,N-dimethyl-1,4-phenylenediamine,anthranilate:NAD+ oxidoreductase; Anthranilate + N,N-Dimethyl-1,4-phenylenediamine + 2 NAD+ <=> Methyl red + 2 NADH + 2 H+ R12036 UDP-alpha-D-glucose:4-O-[(1-D-ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol beta-D-glucosyltransferase (configuration-inverting); n UDP-glucose + 4-O-[(1-D-Ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-[(2-beta-D-Glucosyl-1-D-ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12037 UDP-N-acetyl-alpha-D-glucosamine:4-O-(D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol alpha-N-acetyl-D-glucosaminyltransferase (configuration-retaining); n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-Ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(2-N-Acetyl-alpha-D-glucosaminyl-D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12038 GDP-D-mannose:1-phosphatidyl-1D-myo-inositol 2-alpha-D-mannosyltransferase; GDP-D-mannose + 1-Phosphatidyl-D-myo-inositol <=> GDP + Phosphatidyl-myo-inositol monomannoside R12039 acyl-CoA:phosphatidyl-myo-inositol-monomannoside acyltransferase; Acyl-CoA + Phosphatidyl-myo-inositol monomannoside <=> CoA + Triacylated phosphatidyl-myo-inositol monomannoside R12040 GDP-D-mannose:phosphatidyl-myo-inositol-monomannoside 6-alpha-D-mannosyltransferase; GDP-D-mannose + Phosphatidyl-myo-inositol monomannoside <=> GDP + Phosphatidyl-myo-inositol dimannoside R12041 GDP-D-mannose:triacylated-phosphatidyl-myo-inositol-monomannoside 6-alpha-D-mannosyltransferase; GDP-D-mannose + Triacylated phosphatidyl-myo-inositol monomannoside <=> GDP + Triacylated phosphatidyl-myo-inositol dimannoside R12042 acyl-CoA:phosphatidyl-myo-inositol-dimannoside acyltransferase; Acyl-CoA + Phosphatidyl-myo-inositol dimannoside <=> CoA + Triacylated phosphatidyl-myo-inositol dimannoside R12045 UDP-alpha-D-glucose:(E)-omega-(methylthio)alkyl-thiohydroximate S-beta-D-glucosyltransferase; UDP-glucose + (E)-omega-(Methylthio)alkyl-thiohydroximate <=> UDP + Aliphatic desulfoglucosinolate R12046 UDP-L-rhamnose:flavonol-3-O-D-glucoside L-rhamnosyltransferase; Kaempferol 3-O-glucoside + UDP-L-rhamnose <=> Kaempferol-3-O-rutinoside + UDP R12047 UDP-glucose:afzelin 7-O-glucosyltransferase; Afzelin + UDP-glucose <=> Kaempferol 3-O-rhamnoside-7-O-glucoside + UDP R12048 Stearoyl-CoA + NADPH + H+ + Oxygen <=> Oleoyl-CoA + NADP+ + 2 H2O R12049 Anthraniloyl-CoA + 2 Malonyl-CoA <=> 2-Methylquinolin-4-ol + 3 CO2 + 3 CoA R12050 2-Methylquinolin-4-ol + trans,trans-Farnesyl diphosphate <=> Aurachin D + Diphosphate R12051 aurachin-D,NADPH:oxygen oxidoreductase (N-hydroxylating); Aurachin D + NADPH + H+ + Oxygen <=> Aurachin C + NADP+ + H2O R12052 aurachin-B,NADPH:oxygen oxidoreductase (2',3'-epoxidizing); Aurachin B + NADPH + H+ + Oxygen <=> Aurachin B epoxide + NADP+ + H2O R12053 aurachin-B,NADH:oxygen oxidoreductase (2',3'-epoxidizing); Aurachin B + NADH + H+ + Oxygen <=> Aurachin B epoxide + NAD+ + H2O R12054 Aurachin B epoxide <=> Aurachin A R12055 L-methionine:indole-3-pyruvic acid aminotransferase; L-Methionine + Indolepyruvate <=> 4-Methylthio-2-oxobutanoic acid + L-Tryptophan R12056 ATP + L-Proline <=> Diphosphate + (L-Prolyl)adenylate R12057 (L-Prolyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Prolyl-[pcp] R12058 ent-isokaurene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (ent-isokaurene-2beta,3beta-diol forming); ent-Isokaurene + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> ent-2alpha,3alpha-Dihydroxyisokaurene + 2 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12059 ATP + Pyridinium-3,5-biscarboxylic acid mononucleotide <=> Diphosphate + 5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate R12060 5-Carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine R12061 [Protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide R12062 [LarE]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine pyridin-1-ium-3-carboxylate-5-thiocarboxylate-mononucleotide-lyase (ATP-consuming); [Protein]-L-cysteine + Pyridinium-3,5-biscarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + AMP + Diphosphate R12063 ATP + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide <=> Diphosphate + 1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate R12064 1-(5-O-Phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate + [Protein]-L-cysteine <=> AMP + [Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine R12065 [Protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [Protein]-dehydroalanine + Pyridinium-3,5-bisthiocarboxylate mononucleotide R12066 [LarE]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine pyridin-1-ium-3,5-dicarbothioate-mononucleotide-lyase (ATP-consuming); [Protein]-L-cysteine + Pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide + ATP <=> [Protein]-dehydroalanine + Pyridinium-3,5-biscarboxylic acid mononucleotide + AMP + Diphosphate R12067 6-methoxy-3-methyl-2-(all-trans-polyprenyl)-1,4-benzoquinol,acceptor:oxygen oxidoreductase (5-hydroxylating); 6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + Reduced acceptor + Oxygen <=> 3-Demethylubiquinol + Acceptor + H2O R12068 albendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming); Albendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Albendazole S-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O R12069 fenbendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming); Fenbendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Fenbendazole S-oxide + [Oxidized NADPH---hemoprotein reductase] + H2O R12070 albendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); Albendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Hydroxyalbendazole + [Oxidized NADPH---hemoprotein reductase] + H2O R12071 fenbendazole,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4'-hydroxylating); Fenbendazole + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4'-Hydroxyfenbendazole + [Oxidized NADPH---hemoprotein reductase] + H2O R12072 long-chain fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); Long-chain fatty acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> omega-Hydroxy-long-chain fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O R12073 beta-dihydromenaquinone-9,reduced ferredoxin:oxygen oxidoreductase (omega-hydroxylating); beta-Dihydromenaquinone-9 + 2 Reduced ferredoxin + Oxygen <=> omega-Hydroxy-beta-dihydromenaquinone-9 + 2 Oxidized ferredoxin + H2O R12074 dihydrorhizobitoxine,ferredoxin:oxygen oxidoreductase (3,4 trans-dehydrogenating); Dihydrorhizobitoxine + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Rhizobitoxine + 2 Oxidized ferredoxin + 2 H2O R12075 UDP-N-acetyl-alpha-D-glucosamine:trans,octacis-decaprenyl-phosphate N-acetylglucosaminephosphotransferase; UDP-N-acetyl-D-glucosamine + Decaprenol phosphate <=> UMP + GlcNAc-pyrophosphoryldecaprenol R12076 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase (decarboxylating); (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 4-[(E)-2-Isocyanoethenyl]phenol + Succinate + 2 CO2 + H2O R12077 dTDP-6-deoxy-beta-L-mannose:N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol 3-alpha-L-rhamnosyltransferase; dTDP-L-rhamnose + GlcNAc-pyrophosphoryldecaprenol <=> dTDP + Rhamnosyl-N-acetyl-glucosaminyl-decaprenyl diphosphate R12078 UDP-alpha-D-galactofuranose + Rhamnosyl-N-acetyl-glucosaminyl-decaprenyl diphosphate <=> UDP + Glycolipid 3 R12079 UDP-alpha-D-galactofuranose + Glycolipid 3 <=> UDP + Glycolipid 4 R12080 UDP-alpha-D-galactofuranose + Glycolipid 4 <=> UDP + Glycolipid 5 R12081 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase; (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate + Succinate + CO2 + H2O R12082 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase (decarboxylating, 3-[(Z)-2-isocyanoethenyl]-1H-indole-forming); (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O R12083 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase (decarboxylating, 3-[(E)-2-isocyanoethenyl]-1H-indole-forming); (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + Oxygen <=> 3-[(E)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O R12084 ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing, vanadium-dependent); 12 Reduced ferredoxin + 12 H+ + Nitrogen + 40 ATP + 40 H2O <=> 12 Oxidized ferredoxin + 3 Hydrogen + 2 Ammonia + 40 ADP + 40 Orthophosphate R12085 acetyl-CoA:L-glutamate-5-semialdehyde N-acetyltransferase; Acetyl-CoA + L-Glutamate 5-semialdehyde <=> CoA + N-Acetyl-L-glutamate 5-semialdehyde R12086 Nalpha-[(3R)-hydroxy-acyl]-L-ornithine O-acyltransferase; Lyso-ornithine lipid + Acyl-[acyl-carrier protein] <=> Ornithine lipid + Acyl-carrier protein R12087 2-acetylphloroglucinol C-acetyltransferase; 2 2-Acetylphloroglucinol <=> 2,4-Diacetylphloroglucinol + Phloroglucinol R12088 UDP-alpha-D-glucose:phloretin 2'-O-D-glucosyltransferase; UDP-glucose + Phloretin <=> UDP + Phlorizin R12089 geranyl-diphosphate:3-[(Z)-2-isocyanoethenyl]-1H-indole geranyltransferase; Geranyl diphosphate + 3-[(Z)-2-Isocyanoethenyl]-1H-indole <=> 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + Diphosphate R12090 chanoclavine-I aldehyde:NAD+ oxidoreductase; Dihydrochanoclavine-I aldehyde + NADP+ <=> Chanoclavine-I aldehyde + NADPH + H+ R12091 Dihydrochanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7-didehydroergoline + H2O R12092 thiosulfate:3-phospho-L-serine thiosulfotransferase; O-Phospho-L-serine + Thiosulfate <=> S-Sulfo-L-cysteine + Orthophosphate R12093 Festuclavine <=> Fumigaclavine B R12094 Chanoclavine-I aldehyde + H+ <=> 6,8-Dimethyl-6,7,8,9-tetradehydroergoline + H2O R12095 2-O-(alpha-D-mannopyranosyl)-D-glycerate D-mannohydrolase; 2-O-(alpha-D-Mannosyl)-D-glycerate + H2O <=> D-Mannose + D-Glycerate R12096 [SoxY protein]-S-sulfosulfanyl-L-cysteine sulfohydrolase; [SoxY protein]-S-sulfosulfanyl-L-cysteine + H2O <=> [SoxY protein]-S-sulfanyl-L-cysteine + Sulfate R12097 [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine sulfohydrolase; [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + H2O <=> [SoxY protein]-S-disulfanyl-L-cysteine + Sulfate R12098 S-adenosyl-L-methionine hydrolase (adenosine-forming); (R)-S-Adenosyl-L-methionine + H2O <=> Adenosine + L-Methionine R12099 ATP:[SAMP]-Gly-Gly adenylyltransferase; ATP + [SAMP]-Gly-Gly <=> Diphosphate + [SAMP]-Gly-Gly-AMP R12100 UDP-alpha-D-glucuronate:dolichyl phosphate glucuronosyltransferase (configuration-inverting); UDP-glucuronate + Archaeal dolichyl alpha-D-glucosyl phosphate <=> UDP + Archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate R12101 cannabigerolate:oxygen oxidoreductase (cyclizing, Delta9-tetrahydrocannabinolate-forming); Cannabigerolate + Oxygen <=> Delta9-Tetrahydrocannabinolate + Hydrogen peroxide R12102 Delta9-Tetrahydrocannabinolate <=> Dronabinol + CO2 R12103 Cannabidiolic acid <=> Cannabidiol + CO2 R12104 4-Dimethylallyl-L-abrine <=> Chanoclavine-I R12105 3-oxocholan-24-oyl-CoA Delta4-oxidoreductase; 3-Oxocholan-24-oyl-CoA + NAD+ <=> 3-Oxochol-4-en-24-oyl-CoA + NADH + H+ R12106 3-oxochol-4-en-24-oyl-CoA Delta6-oxidoreductase; 3-Oxochol-4-en-24-oyl-CoA + NAD+ <=> 3-Oxochola-4,6-dien-24-oyl-CoA + NADH + H+ R12107 12alpha-hydroxy-3-oxocholan-24-oyl-CoA Delta4-oxidoreductase; 12alpha-Hydroxy-3-oxocholan-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ R12108 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA Delta6-oxidoreductase; 12alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+ <=> 12alpha-Hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H+ R12109 3-oxocholoyl-CoA Delta4-oxidoreductase; 7alpha,12alpha-Dihydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha,12alpha-Dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ R12110 3-oxochenodeoxycholoyl-CoA Delta4-oxidoreductase; 7alpha-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7alpha-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ R12111 7beta-hydroxy-3-oxochol-24-oyl-CoA Delta4-oxidoreductase; 7beta-Hydroxy-3-oxochol-24-oyl-CoA + NAD+ <=> 7beta-Hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+ R12112 dihydro-4-coumaroyl-CoA:NADP+ 2,3-oxidoreductase; Dihydro-4-coumaroyl-CoA + NADP+ <=> p-Coumaroyl-CoA + NADPH + H+ R12113 dihydroferuloyl-CoA:NADP+ 2,3-oxidoreductase; Dihydroferuloyl-CoA + NADP+ <=> Feruloyl-CoA + NADPH + H+ R12114 8-amino-8-demethylriboflavin-5'-phosphate phosphohydrolase; 8-Amino-8-demethylriboflavin 5'-phosphate + H2O <=> 8-Amino-8-demethylriboflavin + Orthophosphate R12115 carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (phi-ring forming); Carotenoid beta-end group + 2 Acceptor <=> Carotenoid phi-end group + 2 Reduced acceptor R12116 carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (chi-ring forming); Carotenoid beta-end group + 2 Acceptor <=> Carotenoid chi-end group + 2 Reduced acceptor R12117 malonyl-CoA:dihydro-4-coumaroyl-CoA malonyltransferase(cyclizing); Dihydro-4-coumaroyl-CoA + 3 Malonyl-CoA <=> Phloretin + 4 CoA + 3 CO2 R12118 sterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving); 14alpha-Methylsteroid + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Delta14-Steroid + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R12119 14alpha-Methylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Hydroxymethylsteroid + [Oxidized NADPH---hemoprotein reductase] + H2O R12120 14alpha-Hydroxymethylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 14alpha-Formylsteroid + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12121 14alpha-Formylsteroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Delta14-Steroid + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O R12122 abieta-7,13-dien-18-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating); Abietinol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Abietate + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R12123 Abietal + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Abietate + [Oxidized NADPH---hemoprotein reductase] + H2O R12124 1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + Orthophosphate R12125 1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol-3-phosphate phosphohydrolase; 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + H2O <=> 1-O-(2-Acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + Orthophosphate R12126 Coniferyl alcohol <=> (+)-Pinoresinol R12127 Deoxypodophyllotoxin <=> Podophyllotoxin R12128 (+)-germacrene-A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); (+)-Germacrene A + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Germacrene A acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R12129 germacra-1(10),4,11(13)-trien-12-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Germacra-1(10),4,11(13)-trien-12-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12130 germacra-1(10),4,11(13)-trien-12-al,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating); Germacra-1(10),4,11(13)-trien-12-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacrene A acid + [Oxidized NADPH---hemoprotein reductase] + H2O R12131 germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O R12132 6alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Costunolide + H2O R12133 4-Cresol + 2 Oxidized azurin + H2O <=> p-Hydroxybenzyl alcohol + 2 Reduced azurin + 2 H+ R12134 p-Hydroxybenzyl alcohol + 2 Oxidized azurin <=> 4-Hydroxybenzaldehyde + 2 Reduced azurin + 2 H+ R12135 Crocetin dialdehyde <=> Crocetin R12136 (3S)-3-Hydroxycyclocitral <=> Picrocrocin R12137 Picrocrocin <=> Safranal R12138 17-O-Acetylnorajmaline + S-Adenosyl-L-methionine <=> 17-O-Acetylajmaline + S-Adenosyl-L-homocysteine R12140 (9Z,15Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoic acid + H2O <=> 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid R12141 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid + NADPH + H+ <=> 9-Hydroxy-12-oxo-15(Z)-octadecenoic acid + NADP+ R12142 Psilocybin <=> Psilocin R12144 L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase; L-Galactono-1,4-lactone + 4 Ferricytochrome c <=> Dehydroascorbate + 4 Ferrocytochrome c + 4 H+ R12145 Coniferyl alcohol <=> (-)-Pinoresinol R12146 L-galactonate:NAD+ 5-oxidoreductase; L-Galactonate + NAD+ <=> D-Tagaturonate + NADH + H+ R12147 5-aminosalicylate:oxygen 1,2-oxidoreductase (ring-opening); 5-Aminosalicylate + Oxygen <=> (2Z,4E)-4-Amino-6-oxohepta-2,4-dienedioate R12148 medium-chain-fatty-acid:[acyl-carrier protein] ligase (AMP-forming); ATP + Medium-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Medium-chain acyl-[acyl-carrier protein] R12149 (-)-bornane-2,5-dione,FMNH2:oxygen oxidoreductase (1,2-lactonizing); (-)-Bornane-2,5-dione + Reduced FMN + Oxygen <=> (-)-5-Oxo-1,2-campholide + FMN + H2O R12150 L-tyrosine:D-ribulose-5-phosphate lyase (isonitrile-forming); L-Tyrosine + D-Ribulose 5-phosphate <=> (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O R12151 L-tryptophan:D-ribulose-5-phosphate lyase (isonitrile-forming); L-Tryptophan + D-Ribulose 5-phosphate <=> (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O R12152 N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + Ammonia <=> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + H2O R12153 (+)-pinoresinol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (cyclizing); (+)-Pinoresinol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (+)-Piperitol + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12154 (+)-piperitol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (cyclizing); (+)-Piperitol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sesamin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12155 L-galactono-1,5-lactone lactonohydrolase; L-Galactono-1,5-lactone + H2O <=> L-Galactonate R12156 L-galactose:NADP+ oxidoreductase; L-Galactose + NADP+ <=> L-Galactono-1,5-lactone + NADPH + H+ R12157 S-adenosyl-L-methionine:1,6-didemethyltoxoflavin N6-methyltransferase (reumycin-forming); S-Adenosyl-L-methionine + 1,6-Didemethyltoxoflavin <=> S-Adenosyl-L-homocysteine + Reumycin R12158 S-adenosyl-L-methionine:reumycin N1-methyltransferase (toxoflavin-forming); S-Adenosyl-L-methionine + Reumycin <=> S-Adenosyl-L-homocysteine + Toxoflavine R12159 octanoyl-CoA:2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate octanoyltransferase; Octanoyl-CoA + 2-O-[alpha-D-Glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate <=> CoA + 2-O-[6-O-Octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate R12160 UDP-alpha-D-glucose:2-acylphloroglucinol 1-O-beta-glucosyltransferase; UDP-glucose + 2-Acylphloroglucinol <=> UDP + 2-Acylphloroglucinol 1-O-beta-D-glucoside R12161 5-amino-6-(D-ribitylamino)uracil:L-tyrosine 4-hydroxybenzyltransferase; 5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine <=> 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine R12162 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil ammonia-lyase (7,8-didemethyl-8-hydroxy-5-deazariboflavin-forming); 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine <=> 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine R12163 thiosulfate:[SoxY protein]-L-cysteine thiosufotransferase; [SoxY protein]-L-cysteine + Thiosulfate + 2 Ferricytochrome c <=> [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 Ferrocytochrome c + 2 H+ R12164 thiosulfate:[SoxY protein]-S-sulfanyl-L-cysteine thiosufotransferase; [SoxY protein]-S-sulfanyl-L-cysteine + Thiosulfate + 2 Ferricytochrome c <=> [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 Ferrocytochrome c + 2 H+ R12165 hapalindole U,2-oxoglutarate:oxygen oxidoreductase (13-halogenating); Hapalindole U + 2-Oxoglutarate + Oxygen + Cl- <=> Hapalindole G + Succinate + CO2 + H2O R12166 12-epi-fischerindole U,2-oxoglutarate:oxygen oxidoreductase (13-halogenating); 12-epi-Fischerindole U + 2-Oxoglutarate + Oxygen + Cl- <=> 12-epi-Fischerindole G + Succinate + CO2 + H2O R12167 oleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z)-Octadecadienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12168 icosenoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (8,9 cis-dehydrogenating); Icosenoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (8Z,11Z)-Icosadienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12169 (8Z,11Z)-icosadienoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (5,6-cis-dehydrogenating); (8Z,11Z)-Icosadienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (5Z,8Z,11Z)-Icosatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12170 (11Z,14Z,17Z)-icosatrienoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (8,9 cis-dehydrogenating); (11Z,14Z,17Z)-Icosatrienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (8Z,11Z,14Z,17Z)-Icosatetraenoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12171 (11Z,14Z)-icosadienoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (8,9 cis-dehydrogenating); (11Z,14Z)-Icosadienoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 8,11,14-Eicosatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12172 palmitoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (6,7 cis-dehydrogenating); Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Sapienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12173 palmitoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating); Palmitoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Palmitoleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12176 L-threonyl-[L-threonyl-carrier protein],2-oxoglutarate:oxygen oxidoreductase (4-halogenating); L-Threonyl-[L-threonyl-carrier protein] + 2-Oxoglutarate + Oxygen + Cl- <=> 4-Chloro-L-threonyl-[L-threonyl-carrier protein] + Succinate + CO2 + H2O R12177 cyclooctat-9-en-7-ol,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating); Cyclooctat-9-en-7-ol + Reduced acceptor + Oxygen <=> Cyclooctat-9-ene-5,7-diol + Acceptor + H2O R12178 cyclooctat-9-ene-5,7-diol,hydrogen-donor:oxygen oxidoreductase (18-hydroxylating); Cyclooctat-9-ene-5,7-diol + Reduced acceptor + Oxygen <=> Cyclooctatin + Acceptor + H2O R12179 beta-Carotene <=> Echinenone R12180 Echinenone <=> Canthaxanthin R12181 cis-trans-Nepetalactol + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Iridotrial + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R12182 iridotrial,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; Iridotrial + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Deoxyloganetate + [Oxidized NADPH---hemoprotein reductase] + H2O R12183 ATP:cob(II)alamin Cobeta-adenosyltransferase; 2 ATP + 2 Cob(II)alamin + [Reduced NADPH---hemoprotein reductase] <=> 2 Triphosphate + 2 Cobamide coenzyme + [Oxidized NADPH---hemoprotein reductase] R12184 ATP:Cob(II)yrinate diamide Cobeta-adenosyltransferase; 2 ATP + 2 Cob(II)yrinate a,c diamide + [Reduced NADPH---hemoprotein reductase] <=> 2 Triphosphate + 2 Adenosyl cobyrinate a,c diamide + [Oxidized NADPH---hemoprotein reductase] R12185 Ammonia + HCO3- <=> Carbamate + H2O R12187 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid-IVA palmitoyltransferase; Palmitoylphosphatidylcholine + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IVB R12188 L-cysteine-S-conjugate thiol-lyase (deaminating; 2-aminoprop-2-enoate-forming); L-Cysteine-S-conjugate + H2O <=> Thiol + Ammonia + Pyruvate R12193 octadecanoyl-[acyl-carrier protein]:KDO2-lipid-IVA O-octadecanoyltransferase; Octadecanoyl-[acyl-carrier protein] + H. pylori KDO2-lipid IVA <=> Stearoyl-KDO2-lipid IVA + Acyl-carrier protein R12194 tetradecanoyl-[acyl-carrier protein]:octadecanoyl-KDO2-lipid-IVA O-tetradecanoyltransferase; Tetradecanoyl-[acp] + Stearoyl-KDO2-lipid IVA <=> H. pylori KDO2-lipid A + Acyl-carrier protein R12196 KDO2-lipid-A acyloxyacylhydrolase; KDO2-lipid A + H2O <=> 3'-O-Deacylated KDO2-lipid A + (R)-3-(Tetradecanoyloxy)tetradecanoic acid R12197 tetradecanoyl-[acyl-carrier protein]:(9Z)-hexadec-9-enoyl-KDO2-lipid IVA O-tetradecanoyltransferase; Tetradecanoyl-[acp] + (9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) <=> Palmitoleoyl-myristoyl-KDO2-lipid A + Acyl-carrier protein R12198 lipid-IVB hydroxyacylhydrolase; Lipid IVB + H2O <=> Deacyl-lipid IVB + (R)-3-Hydroxymyristic acid R12199 lipid-IVA hydroxyacylhydrolase; 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + H2O <=> Deacyl-lipid IVA + (R)-3-Hydroxymyristic acid R12200 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:deacyl-lipid-IVA palmitoyltransferase; Palmitoylphosphatidylcholine + Deacyl-lipid IVA <=> 2-Acyl-sn-glycero-3-phosphocholine + Deacyl-lipid IVB R12201 hexa-acylated-KDO2-lipid-A phosphohydrolase; H. pylori KDO2-lipid A + H2O <=> 1-Dephospho-KDO2-lipid A + Orthophosphate R12202 phosphatidylethanolamine:1-dephospho-KDO2-lipid-A ethanolaminephosphotransferase; Phosphatidylethanolamine + 1-Dephospho-KDO2-lipid A <=> Diacylglycerol + 1-PEtN-KDO2-lipid A R12203 1-PEtN-KDO-lipid-A phosphohydrolase; 1-PEtN-KDO-lipid A + H2O <=> 4'-Dephosphorylated 1-PEtN-KDO-lipid A + Orthophosphate R12204 4'-dephosphorylated-1-PEtN-KDO-lipid-A acyloxyacylhydrolase; 4'-Dephosphorylated 1-PEtN-KDO-lipid A + H2O <=> H. pylori KDO-lipid A + (R)-3-(Tetradecanoyloxy)hexadecanoic acid R12205 linoleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (15,16 cis-dehydrogenating); Linoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (9Z,12Z,15Z)-Octadecatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O R12206 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid-IIA palmitoyltransferase; Palmitoylphosphatidylcholine + Lipid IIA <=> 2-Acyl-sn-glycero-3-phosphocholine + Lipid IIB R12207 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate:lipid IVB 4-amino-4-deoxy-L-arabinopyranosyltransferase; Undecaprenyl phosphate alpha-L-Ara4N + Lipid IVB <=> Lipid IIB + di-trans,poly-cis-Undecaprenyl phosphate R12208 (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside beta-D-glucosidase; DIMBOA-glucoside + H2O <=> DIMBOA + D-Glucose R12209 (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside beta-D-glucosidase; DIBOA-glucoside + H2O <=> DIBOA + D-Glucose R12210 KDO2-lipid-A,2-oxoglutarate:oxygen oxidoreductase (ester-linked acyl 2-hydroxylase); KDO2-lipid A + 2-Oxoglutarate + Oxygen <=> (S)-2-Hydroxymyristate-modified lipid A + Succinate + CO2 R12211 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:KDO2-lipid-A palmitoyltransferase; Palmitoylphosphatidylcholine + KDO2-lipid A <=> 2-Acyl-sn-glycero-3-phosphocholine + C16-KDO2-lipid A R12212 oxaloacetate carboxy-lyase (pyruvate-forming; Na+-extruding); Oxaloacetate + 2 Sodium cation <=> Pyruvate + CO2 + 2 Sodium cation R12213 S-adenosyl-L-methionine:naringenin 4'-O-methyltransferase; Naringenin + S-Adenosyl-L-methionine <=> Isosakuranetin + S-Adenosyl-L-homocysteine R12214 cadaverine:2-oxoglutarate aminotransferase; Cadaverine + 2-Oxoglutarate <=> 5-Aminopentanal + L-Glutamate R12215 5-aminopentanal:NAD+ 1-oxidoreductase; 5-Aminopentanal + NAD+ + H2O <=> 5-Aminopentanoate + NADH + H+ R12216 glutarate,2-oxoglutarate:oxygen oxidoreductase ((S)-2-hydroxyglutarate-forming); Glutarate + 2-Oxoglutarate + Oxygen <=> (S)-2-Hydroxyglutarate + Succinate + CO2 R12217 (S)-2-hydroxyglutarate:quinone oxidoreductase; (S)-2-Hydroxyglutarate + Quinone <=> 2-Oxoglutarate + Hydroquinone R12218 flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating); Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2-Hydroxyflavanone + [Oxidized NADPH---hemoprotein reductase] + H2O R12219 KDO2-lipid-A-1-(2-aminoethyl phosphate) hydrolase; 1-PEtN-KDO2-lipid A + H2O <=> 1-PEtN-KDO-lipid A + 3-Deoxy-D-manno-octulosonate R12220 D-glucosamine 6-phosphate 4-epimerase; D-Glucosamine 6-phosphate <=> D-Galactosamine 6-phosphate R12221 alpha-D-galactosamine 1,6-phosphomutase; D-Galactosamine 6-phosphate <=> alpha-D-Galactosamine 1-phosphate R12222 scopoletin,2-oxoglutarate:oxygen oxidoreductase (8-hydroxylating); Scopoletin + 2-Oxoglutarate + Oxygen <=> Fraxetin + Succinate + CO2 R12223 fraxetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (5-hydroxylating); Fraxetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Sideretin + [Oxidized NADPH---hemoprotein reductase] + H2O R12224 dolabradiene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3beta-hydroxy-15,16-epoxydolabrene-forming); Dolabradiene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 15,16-Epoxydolabrene + H2O + [Oxidized NADPH---hemoprotein reductase] R12225 15,16-epoxydolabrene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3beta-hydroxy-15,16-epoxydolabrene-forming); 15,16-Epoxydolabrene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> 3beta-Hydroxy-15,16-epoxydolabrene + H2O + [Oxidized NADPH---hemoprotein reductase] R12226 (S)-beta-macrocarpene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (zealexin A1-forming); (S)-beta-Macrocarpene + 3 Oxygen + 3 [Reduced NADPH---hemoprotein reductase] <=> Zealexin A1 + 4 H2O + 3 [Oxidized NADPH---hemoprotein reductase] R12227 (S)-beta-macrocarpene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (S)-beta-Macrocarpene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> [(4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H2O + [Oxidized NADPH---hemoprotein reductase] R12228 [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; [(4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + 2 H2O + [Oxidized NADPH---hemoprotein reductase] R12229 (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; (4S)-4-(5,5-Dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Zealexin A1 + H2O + [Oxidized NADPH---hemoprotein reductase] R12230 (+)-cis,trans-nepetalactol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating); cis-trans-Nepetalactol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 7-Deoxyloganetate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O R12231 (+)-cis,trans-nepetalactol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; cis-trans-Nepetalactol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7-Deoxyloganetic alcohol + [Oxidized NADPH---hemoprotein reductase] + H2O R12232 indole-3-carbonyl nitrile,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating); Indole-3-carbonyl nitrile + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Hydroxyindole-3-carbonyl nitrile + [Oxidized NADPH---hemoprotein reductase] + H2O R12233 very-long-chain acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (omega9,omega8-cis-dehydrogenating); 1-Hexacosanoyl-2-acyl-[phosphoglycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-[(17Z)-Hexacos-17-enoyl]-2-acyl-[phosphoglycerolipid] + 2 Ferricytochrome b5 + 2 H2O R12234 very-long-chain acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (omega9,omega8-cis-dehydrogenating); 1-Tetracosanoyl-2-acyl-[phosphoglycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 1-[(15Z)-Tetracos-15-enoyl]-2-acyl-[phosphoglycerolipid] + 2 Ferricytochrome b5 + 2 H2O R12235 (2S)-2-amino-3-(4-hydroxyphenyl)propanal:NADP+ oxidoreductase (ATP-forming); L-Tyrosinal + NADP+ + AMP + Diphosphate <=> L-Tyrosine + NADPH + H+ + ATP R12236 meromycolyl-[acyl-carrier protein]:NAD+ oxidoreductase; Meromycolyl-[acyl-carrier protein] + NAD+ <=> trans-Delta2-Meromycolyl-[acyl-carrier protein] + NADH + H+ R12237 staphylopine:NADP+ oxidoreductase [(2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate]-forming; Staphylopine + NADP+ + H2O <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + Pyruvate + NADPH + H+ R12238 S-adenosyl-L-methionine:menaquinone C8-methyltransferase; 2 S-Adenosyl-L-methionine + Menaquinone + Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + 8-Methylmenaquinone + Oxidized flavodoxin R12239 S-adenosyl-L-methionine:2-demethylmenaquinone C8-methyltransferase; 2 S-Adenosyl-L-methionine + 2-Demethylmenaquinone + Reduced flavodoxin <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + 2-Demethyl-8-methylmenaquinone + Oxidized flavodoxin R12240 acyl-[acyl-carrier protein]:phosphate acyltransferase; Acyl-[acyl-carrier protein] + Orthophosphate <=> Acyl phosphate + Acyl-carrier protein R12241 acyl phosphoate:sn-glycerol 3-phosphate acyltransferase; Acyl phosphate + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Orthophosphate R12242 acetyl-CoA:alpha-D-galactosamine-1-phosphate N-acetyltransferase; Acetyl-CoA + alpha-D-Galactosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-galactosamine 1-phosphate R12243 2-O-alpha-D-glucopyranosyl-glycerol:phosphate alpha-D-glucosyltransferase (configuration-retaining); 2-O-(alpha-D-Glucopyranosyl)glycerol + Orthophosphate <=> D-Glucose 1-phosphate + Glycerol R12244 UDP-alpha-D-xylose:3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein] xylosyltransferase; UDP-D-xylose + G13094 <=> UDP + G13095 R12245 ATP:5-amino-1-(beta-D-ribosyl)imidazole 5'-phosphotransferase; ATP + 5-Amino-1-(beta-D-ribosyl)imidazole <=> ADP + Aminoimidazole ribotide R12246 ATP:cytidine 5'-diphosphoramidate 3'-phosphotransferase; ATP + Cytidine 5'-diphosphoramidate <=> ADP + Cytidine 3'-phospho-5'-diphosphoramidate R12247 CTP:phosphoglutamine cytidylyltransferase; CTP + N5-Phospho-L-glutamine <=> Diphosphate + N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine R12248 5-phospho-D-xylono-1,4-lactone hydrolase; D-Xylono-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-D-xylonate R12249 5-phospho-L-arabino-1,4-lactone hydrolase; L-Arabino-1,4-lactone 5-phosphate + H2O <=> 5-Phospho-L-arabinate R12250 2-O-(alpha-D-glucopyranosyl)-D-glycerate D-glucohydrolase; 2-O-(alpha-D-Glucopyranosyl)-D-glycerate + H2O <=> D-Glucose + D-Glycerate R12251 N5-(cytidine 5'-diphosphoramidyl)-L-glutamine amidohydrolase; N5-(Cytidine 5'-diphosphoramidyl)-L-glutamine + H2O <=> Cytidine 5'-diphosphoramidate + L-Glutamate R12252 (R)-3-(4-hydroxyphenyl)lactate:NADP+ oxidoreductase; (R)-3-(3,4-Dihydroxyphenyl)lactate + NADP+ <=> 3-(3,4-Dihydroxyphenyl)pyruvate + NADPH + H+ R12253 7-deoxyloganetic alcohol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase; 7-Deoxyloganetic alcohol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Iridotrial + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12254 1,4-Dihydroxy-2-naphthoate <=> 2-Carboxy-1,4-naphthoquinone R12255 phytyl-diphosphate:2-carboxy-1,4-naphthoquinone phytyltransferase; Phytyl diphosphate + 2-Carboxy-1,4-naphthoquinone <=> 2-Phytyl-1,4-naphthoquinone + Diphosphate + CO2 R12256 (R)-(indol-3-yl)lactate:NAD+ oxidoreductase; (R)-(Indol-3-yl)lactate + NAD+ <=> Indolepyruvate + NADH + H+ R12257 cis-3-alkyl-4-alkyloxetan-2-one carboxy-lyase (cis-alkene-forming); cis-3-Alkyl-4-alkyloxetan-2-one <=> cis-Alkene + CO2 R12258 ent-copalyl-diphosphate diphosphate-lyase (dolabradiene-forming); ent-Copalyl diphosphate <=> Dolabradiene + Diphosphate R12259 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-ent-eudesmane-5,11-diol-forming); trans,trans-Farnesyl diphosphate + 2 H2O <=> 7-epi-ent-Eudesmane-5,11-diol + Diphosphate R12260 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-selinene-forming); trans,trans-Farnesyl diphosphate <=> alpha-Selinene + Diphosphate R12261 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-epieremophilene-forming]; trans,trans-Farnesyl diphosphate <=> (-)-5-Epieremophilene + Diphosphate R12262 S-adenosyl-L-methionine:narcotoline 4'-O-methyltransferase; Narcotoline + S-Adenosyl-L-methionine <=> alpha-Narcotine + S-Adenosyl-L-homocysteine R12263 S-adenosyl-L-methionine:nocamycin E O-methyltransferase; S-Adenosyl-L-methionine + Nocamycin E <=> S-Adenosyl-L-homocysteine + Nocamycin I R12264 S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase; S-Adenosyl-L-methionine + Xanthohumol <=> S-Adenosyl-L-homocysteine + 4-O-Methylxanthohumol R12265 isopyridoxal:NAD+ oxidoreductase (5-pyridoxate-forming); Isopyridoxal + NAD+ + H2O <=> 3-Hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADH + H+ R12266 germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8beta-hydroxylating); Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8beta-Hydroxygermacrene A acid + [Oxidized NADPH---hemoprotein reductase] + H2O R12267 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); 8beta-Hydroxygermacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O R12268 6alpha,8beta-Dihydroxygermacra-1(10),4,11(13)-trien-12-oate <=> Eupatolide + H2O R12269 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, beta-pinacene-forming); Geranylgeranyl diphosphate <=> beta-Pinacene + Diphosphate R12270 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating); 8beta-Hydroxygermacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eupatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12271 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate L-glutamate-epimerase; ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + H2O <=> AMP + Diphosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate R12272 UDP-N-acetylmuramoyl-L-alanine---L-glutamate ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanine + L-Glutamate <=> ADP + Orthophosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate R12273 germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8alpha-hydroxylating); Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate + [Oxidized NADPH---hemoprotein reductase] + H2O R12274 8alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oate <=> 8-epi-Inunolide + H2O R12275 germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8alpha-hydroxylating); Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 8-epi-Inunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12276 flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming); Flavanone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Flavone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12277 liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (7,4'-dihydroxyflavone-forming); Liquiritigenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7,4'-Dihydroxyflavone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12278 naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (apigenin-forming); Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Apigenin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12279 eriodictyol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (luteolin-forming); Eriodictyol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Luteolin + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12280 lycopaoctaene:NADP+ oxidoreductase; geranylgeranyl-diphosphate:geranylgeranyl diphosphate geranylgeranyltransferase (reducing, lycopaoctaene-forming); Prephytoene diphosphate + NADPH + H+ <=> Lycopaoctaene + Diphosphate + NADP+ R12281 geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (lycopaoctaene-forming); 2 Geranylgeranyl diphosphate + NADPH + H+ <=> Lycopaoctaene + 2 Diphosphate + NADP+ R12282 Tetrahydroalstonine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Alstonine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O + 2 H+ R12283 dimethylallyl-diphosphate:all-trans-lycopene dimethylallyltransferase (hydrating, nonaflavuxanthin-forming); Dimethylallyl diphosphate + Lycopene + Acceptor + H2O <=> Nonaflavuxanthin + Reduced acceptor + Diphosphate R12284 dimethylallyl-diphosphate:nonaflavuxanthin dimethylallyltransferase (hydrating, flavuxanthin-forming); Dimethylallyl diphosphate + Nonaflavuxanthin + Acceptor + H2O <=> Flavuxanthin + Reduced acceptor + Diphosphate R12285 dimethylallyl-diphosphate:all-trans-lycopene dimethylallyltransferase (hydrating, dihydroisopentenyldehydrorhodopin-forming); Dimethylallyl diphosphate + Lycopene + H2O <=> Dihydroisopentenyldehydrorhodopin + Diphosphate R12286 dimethylallyl-diphosphate:isopentenyldehydrorhodopin dimethylallyltransferase (hydrating, dihydrobisanhydrobacterioruberin-forming); Dimethylallyl diphosphate + Isopentenyldehydrorhodopin + H2O <=> Dihydrobisanhydrobacterioruberin + Diphosphate R12287 long-chain-fatty acyl-CoA:alpha,alpha-trehalose 2-acyltransferase; Long-chain acyl-CoA + alpha,alpha-Trehalose <=> 2-(Long-chain-fatty acyl)-trehalose + CoA R12288 mycolipenoyl-CoA:2-(long-chain-fatty acyl)-trehalose 3-mycolipenoyltransferase; Mycolipenoyl-CoA + 2-(Long-chain-fatty acyl)-trehalose <=> 2-(Long-chain-fatty acyl)-3-mycolipenoyl-trehalose + CoA R12289 3-oxoacyl-[acyl-carrier protein]:glycerone phosphate 3-oxonacylltransferase; Medium-chain 3-oxoacyl-[acyl-carrier protein] + Glycerone phosphate <=> 2-Oxo-3-(phosphooxy)propyl 3-oxoalkanoate + Acyl-carrier protein R12290 UDP-alpha-D-glucose:2'-hydroxy-beta-oxodihydrochalcone C6/8-beta-D-glucosyltransferase; UDP-glucose + 2'-Hydroxy-beta-oxodihydrochalcone <=> UDP + 3'-(beta-D-Glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone R12291 5-methyltetrahydrosarcinapterin:CoM 2-methyltransferase; 5-Methyl-H4SPT + Coenzyme M + 2 Sodium cation(side 1) <=> Tetrahydrosarcinapterin + 2-(Methylthio)ethanesulfonate + 2 Sodium cation(side 2) R12292 G13087 + UDP-N-acetyl-D-galactosamine <=> O-mannose core M3 + UDP R12293 O-mannose core M3 + ATP <=> Phospho-core M3 + ADP R12294 Phospho-core M3 + CDP-ribitol <=> G13093 + CMP R12295 G13093 + CDP-ribitol <=> G13094 + CMP R12296 G13095 + UDP-D-glucuronate <=> G13096 + UDP R12297 G13096 + UDP-D-xylose <=> G13097 + UDP R12298 G13097 + UDP-D-glucuronate <=> G13098 + UDP R12299 ditrans,polycis-dolichol:NADP+ 2,3-oxidoreductase; Dolichol + NADP+ <=> Polyprenol + NADPH + H+ R12300 malonate:CoA ligase (AMP-forming); ATP + Malonate + CoA <=> AMP + Diphosphate + Malonyl-CoA R12301 o-Methoxyphenol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Catechol + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O R12302 isoeugenol:oxygen 7,8-oxidoreductase (bond-cleaving); Isoeugenol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde R12303 (1H-indol-3-yl)acetate carboxy-lyase (skatole-forming); Indole-3-acetate <=> Skatole + CO2 R12304 D-ornithine carboxy-lyase; D-Ornithine <=> Putrescine + CO2 R12305 D-lysine carboxy-lyase; D-Lysine <=> Cadaverine + CO2 R12306 (2E)-3-(4-hydroxyphenyl)prop-2-enoyl-CoA,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating); p-Coumaroyl-CoA + 2-Oxoglutarate + Oxygen <=> 2,4-Dihydroxycinnamoyl-CoA + Succinate + CO2 R12307 (4R)-4,2'-dihydroxyisoflavan hydro-lyase (pterocarpan-forming); (4R)-4,2'-Dihydroxyisoflavan <=> Pterocarpan + H2O R12308 L-2,3-diaminopropanoate:citrate ligase (AMP, 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate-forming); ATP + L-2,3-Diaminopropanoate + Citrate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate R12309 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate carboxy-lyase (2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate-forming); 2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate <=> 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2 R12310 2,4-Dihydroxycinnamoyl-CoA <=> Umbelliferone + CoA R12311 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate:L-2,3-diaminopropanoate ligase {2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate-forming}; ATP + 2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-Diaminopropanoate <=> AMP + Diphosphate + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate R12312 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate:2-oxoglutarate ligase (staphyloferrin B-forming); ATP + 2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-Oxoglutarate <=> AMP + Diphosphate + Staphyloferrin B R12313 histidine racemase; L-Histidine <=> D-Histidine R12314 6-sulfo-D-quinovose 1-epimerase; 6-Sulfo-alpha-D-quinovose <=> 6-Sulfo-beta-D-quinovose R12315 [protein]-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3S-hydroxylating); Protein lysine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3S)-3-hydroxy-L-lysine + Succinate + CO2 R12316 G10558 + UDP-N-acetyl-D-glucosamine <=> G13127 + UDP R12317 sterol,reduced ferredoxin:oxygen oxidoreductase (14-methyl cleaving); 14alpha-Methylsteroid + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> Delta14-Steroid + Formate + 6 Oxidized ferredoxin + 4 H2O R12318 14alpha-Methylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Hydroxymethylsteroid + 2 Oxidized ferredoxin + H2O R12319 dimethyl sulfide,NADH:oxygen oxidoreductase (S-oxidizing); Dimethyl sulfide + NADH + H+ + Oxygen <=> Dimethyl sulfoxide + NAD+ + H2O R12320 dimethyl sulfoxide,NADH:oxygen oxidoreductase (S-oxidizing); Dimethyl sulfoxide + NADH + H+ + Oxygen <=> Dimethyl sulfone + NAD+ + H2O R12321 14alpha-Hydroxymethylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> 14alpha-Formylsteroid + 2 Oxidized ferredoxin + 2 H2O R12322 14alpha-Formylsteroid + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Delta14-Steroid + Formate + 2 Oxidized ferredoxin + H2O R12323 lanosterol,reduced ferredoxin:oxygen oxidoreductase (14-methyl cleaving); Lanosterol + 6 Reduced ferredoxin + 6 H+ + 3 Oxygen <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 6 Oxidized ferredoxin + 4 H2O R12324 luteothin,ferredoxin:oxygen oxidoreductase (aureothin-forming); Luteothin + 4 Reduced ferredoxin + 2 Oxygen + 4 H+ <=> Aureothin + 4 Oxidized ferredoxin + 3 H2O R12325 Luteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> (7R)-7-Hydroxyluteothin + 2 Oxidized ferredoxin + H2O R12326 (7R)-7-Hydroxyluteothin + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Aureothin + 2 Oxidized ferredoxin + 2 H2O R12328 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, NADH); Acetyl-CoA + n Malonyl-CoA + n NADPH + n NADH + 2n H+ <=> Long-chain acyl-CoA + n CoA + n CO2 + n NADP+ + n NAD+ + n H2O R12329 long-chain acyl-[acyl-carrier protein] hydrolase; Long-chain acyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Long-chain fatty acid R12330 ATP:beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol phosphotransferase; ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol R12331 beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol + Ammonia <=> Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + Orthophosphate R12332 cyanuric acid amidohydrolase; Cyanuric acid + H2O <=> 1-Carboxybiuret R12333 1-carboxybiuret amidohydrolase; 1-Carboxybiuret + H2O <=> Urea-1,3-dicarboxylate + Ammonia R12334 Urea-1,3-dicarboxylate <=> Urea-1-carboxylate + CO2 R12335 1-Carboxybiuret <=> Biuret + CO2 R12336 S-adenosyl-L-methionine:demethylluteothin O-methyltransferase; S-Adenosyl-L-methionine + Demethylluteothin <=> S-Adenosyl-L-homocysteine + Luteothin R12337 malonyl-CoA:malonyl-CoA malonyltransferase ((2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal-forming); 6 Malonyl-CoA + 5 NADPH + NADH + 6 H+ <=> (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + 6 CoA + 5 NADP+ + NAD+ + 6 CO2 + 4 H2O R12338 GDP-alpha-D-mannose:bis(myo-inositol)-1,3'-phosphate 2-beta-D-mannosyltransferase; 2 GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> 2 GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate R12339 GDP-alpha-D-mannose:bis(myo-inositol)-1,3'-phosphate 2-beta-D-mannosyltransferase; GDP-mannose + Bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate R12340 GDP-alpha-D-mannose:2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate 2-beta-D-mannosyltransferase; GDP-mannose + 2-O-(beta-D-Mannosyl)-bis(myo-inositol) 1,3'-phosphate <=> GDP + 2-O-(beta-D-Mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate R12341 S-adenosyl-L-methionine:D-histidine N-[(3S)-3-amino-3-carboxypropyl]-transferase; S-Adenosyl-L-methionine + D-Histidine <=> (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 5'-Methylthioadenosine R12342 ADP:L-serine 3-phosphotransferase; ADP + L-Serine <=> AMP + O-Phospho-L-serine R12343 (2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol:pyruvate aminotransferase; (2E,5S,6E,8E,10E)-1-Aminododeca-2,6,8,10-tetraen-5-ol + Pyruvate <=> (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + L-Alanine R12344 ATP:L-serine 3-phosphotransferase; ATP + L-Serine <=> ADP + O-Phospho-L-serine R12345 cyclic bis(3'->5')diadenylate 3'-adenylylhydrolase; Cyclic di-3',5'-adenylate + H2O <=> 5'-O-Phosphonoadenylyl-(3'->5')-adenosine R12346 5'-O-phosphonoadenylyl-(3'->5')-adenosine phosphohydrolase; 5'-O-Phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP R12347 3-O-acetylpapaveroxine acetatehydrolase; 3-O-Acetylpapaveroxine + H2O <=> Narcotine hemiacetal + Acetate R12348 3'-(hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose:3'-(hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose 6,6'-di(hydroxy)phthioceranyltransferase; 3 3'-(Hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-alpha,alpha-trehalose <=> 3,6,6'-Tris-(hydroxy)phthioceranyl-2-palmitoyl(stearoyl)-2'-sulfo-alpha,alpha-trehalose + 2 2'-Palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose R12349 sucrose:(1->6)-alpha-D-glucan 3-alpha-D-[(1->3)-alpha-D-glucosyl]-transferase; Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->3)-alpha-D-glucose branch R12350 G00146 + Dolichyl phosphate D-mannose <=> G13128 + Dolichyl phosphate R12351 G13128 + Phosphatidylethanolamine <=> G00148 + 1,2-Diacyl-sn-glycerol R12352 N3-fumaroyl-L-2,3-diaminopropanoate:L-glutamine amido-ligase (AMP-forming); N3-Fumaroyl-L-2,3-diaminopropanoate + L-Glutamine + ATP + H2O <=> 3-{[(2E)-4-Amino-4-oxobut-2-enoyl]amino}-L-alanine + L-Glutamate + AMP + Diphosphate R12353 D-ornithine:citrate ligase (AMP-forming); D-Ornithine + Citrate + ATP <=> N5-Citryl-D-ornithine + AMP + Diphosphate R12354 N5-[(S)-citryl]-D-ornithine:citrate ligase (AMP, staphyloferrin A-forming); N5-Citryl-D-ornithine + Citrate + ATP <=> Staphyloferrin A + AMP + Diphosphate R12355 Squalene + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (S)-2,3-Epoxysqualene + 2 Ferricytochrome b5 + H2O R12356 propanoyl-CoA:oxygen 2-oxidoreductase; Propanoyl-CoA + Oxygen <=> Propenoyl-CoA + Hydrogen peroxide R12357 3beta-hydroxy-4,4-dimethylsteroid,NADH:oxygen oxidoreductase; 3beta-Hydroxy-4,4-dimethylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NAD+ + H2O R12358 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid,NADH:oxygen oxidoreductase; 3beta-Hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NAD+ + 2 H2O R12359 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid,NADH:oxygen oxidoreductase; 3beta-Hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + H+ + Oxygen <=> 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ + H2O R12360 3beta-hydroxy-4,4-dimethylsteroid,NADH:oxygen oxidoreductase (C-4beta-hydroxylating); 3beta-Hydroxy-4,4-dimethylsteroid + 3 NADH + 3 H+ + 3 Oxygen <=> 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + 3 NAD+ + 4 H2O R12361 3beta-hydroxysteroid-4beta-carboxylate:NAD+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD+ <=> 4alpha-Methyl-3-oxosteroid + NADH + CO2 + H+ R12362 3beta-hydroxysteroid-4beta-carboxylate:NADP+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP+ <=> 4alpha-Methyl-3-oxosteroid + NADPH + CO2 + H+ R12363 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, hydropyrene-forming); Geranylgeranyl diphosphate <=> Hydropyrene + Diphosphate R12364 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, hydropyrenol-forming); Geranylgeranyl diphosphate + H2O <=> Hydropyrenol + Diphosphate R12365 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, isoelisabethatriene-forming); Geranylgeranyl diphosphate <=> Isoelisabethatriene + Diphosphate R12366 3beta-hydroxysteroid-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxysteroid-4alpha-carboxylate + NAD+ <=> 3-Oxosteroid + NADH + CO2 + H+ R12367 beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (16alpha-hydroxylating); beta-Amyrin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16alpha-Hydroxy-beta-amyrin + [Oxidized NADPH---hemoprotein reductase] + H2O R12368 24-methylidenecycloartanol,ferrocytochrome-b5:oxygen oxidoreductase; 24-Methylidenecycloartanol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-(Hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferricytochrome b5 + H2O R12369 4alpha-(hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase; 4alpha-(Hydroxymethyl)-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferricytochrome b5 + 2 H2O R12370 4alpha-formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase; 4alpha-Formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O R12371 3beta-hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + NAD+ <=> Cycloeucalenone + NADH + CO2 + H+ R12372 24-methylenelophenol,ferrocytochrome-b5:oxygen oxidoreductase; 24-Methylenelophenol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-(Hydroxymethyl)ergosta-7,24(24(1))-dien-3beta-ol + 2 Ferricytochrome b5 + H2O R12373 4alpha-(hydroxymethyl)ergosta-7,24(241)-dien-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase; 4alpha-(Hydroxymethyl)ergosta-7,24(24(1))-dien-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 4alpha-Formylergosta-7,24(24(1))-dien-3beta-ol + 2 Ferricytochrome b5 + 2 H2O R12374 4alpha-formylergosta-7,24(24(1))-dien-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase; 4alpha-Formylergosta-7,24(24(1))-dien-3beta-ol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + 2 Ferricytochrome b5 + H2O R12375 3beta-hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2 + H+ R12376 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol:NAD+ 3-oxidoreductase (decarboxylating); 4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + NAD+ <=> Avenastenone + NADH + CO2 + H+ R12377 24-methylidenecycloartanol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating); 24-Methylidenecycloartanol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O R12378 24-methylenelophenol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating); 24-Methylenelophenol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O R12379 24-ethylidenelophenol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating); 24-Ethylidenelophenol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Ferricytochrome b5 + 4 H2O R12380 (S)-methylmalonyl-CoA:palmitoyl-[(hydroxy)phthioceranic acid synthase] methylmalonyltransferase (phthioceranyl-[(hydroxy)phthioceranic acid synthase]-forming); 8 (S)-Methylmalonyl-CoA + Palmitoyl-[(hydroxy)phthioceranic acid synthase] + 16 NADPH + 16 H+ <=> 8 CoA + C40-Phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 16 NADP+ + 8 CO2 + 8 H2O R12381 (S)-methylmalonyl-CoA:palmitoyl-[(hydroxy)phthioceranic acid synthase] methylmalonyltransferase (phthioceranyl-[(hydroxy)phthioceranic acid synthase]-forming); 7 (S)-Methylmalonyl-CoA + Palmitoyl-[(hydroxy)phthioceranic acid synthase] + 14 NADPH + 14 H+ <=> 7 CO2 + C37-Phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 14 NADP+ + 7 CoA + 7 H2O R12382 UDP-alpha-D-glucose:(20S)-protopanaxadiol 20-O-glucosyltransferase (configuration-inverting); UDP-glucose + Protopanaxadiol <=> UDP + Ginsenoside C-K R12383 UDP-alpha-D-glucose:protopanaxadiol-type ginsenoside 3-O-glucosyltransferase (configuration-retaining); UDP-glucose + Protopanaxadiol <=> UDP + (20S)-Ginsenoside Rh2 R12384 UDP-alpha-D-glucose:protopanaxadiol-type ginsenoside 3-O-glucosyltransferase (configuration-retaining); UDP-glucose + Ginsenoside C-K <=> UDP + Ginsenoside F2 R12385 UDP-alpha-D-glucose:3-O-glucosyl-protopanaxadiol-type ginsenoside 2''-O-glucosyltransferase; UDP-glucose + (20S)-Ginsenoside Rh2 <=> UDP + Ginsenoside Rg3 R12386 UDP-alpha-D-glucose:3-O-glucosyl-protopanaxadiol-type ginsenoside 2''-O-glucosyltransferase; UDP-glucose + Ginsenoside F2 <=> UDP + Ginsenoside Rd R12387 UDP-alpha-D-glucose:ginsenoside F1 6-O-glucosyltransferase; UDP-glucose + Ginsenoside F1 <=> UDP + Ginsenoside Rg1 R12388 UDP-alpha-D-glucose:protopanaxatriol 6-O-glucosyltransferase; UDP-glucose + Protopanaxatriol <=> UDP + Ginsenoside Rh1 R12389 UDP-alpha-D-glucose:oleanolate 3-O-glucosyltransferase; UDP-glucose + Oleanolic acid <=> UDP + Oleanolate 3-O-beta-D-glucoside R12390 O-acetyl-ADP-D-ribose carboxylesterase; 3''-O-Acetyl-ADP-D-ribose + H2O <=> ADP-ribose + Acetate R12391 O-acetyl-ADP-D-ribose carboxylesterase; O-Acetyl-ADP-ribose + H2O <=> ADP-ribose + Acetate R12392 2,4-diacetylphloroglucinol acetylhydrolase; 2,4-Diacetylphloroglucinol + H2O <=> 2-Acetylphloroglucinol + Acetate R12393 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; ATP + Octadecanoic acid <=> Diphosphate + (Stearoyl)adenylate R12394 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; (Stearoyl)adenylate + Peptidyl-carrier protein <=> AMP + Stearoyl-[(hydroxy)phthioceranic acid synthase] R12395 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; ATP + Octadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Stearoyl-[(hydroxy)phthioceranic acid synthase] R12396 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; ATP + Hexadecanoic acid <=> Diphosphate + (Palmitoyl)adenylate R12397 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; (Palmitoyl)adenylate + Peptidyl-carrier protein <=> AMP + Palmitoyl-[(hydroxy)phthioceranic acid synthase] R12398 palmitate:holo-[(hydroxy)phthioceranic acid synthase] ligase; ATP + Hexadecanoic acid + Peptidyl-carrier protein <=> AMP + Diphosphate + Palmitoyl-[(hydroxy)phthioceranic acid synthase] R12399 cycloeucalenol:NADP+ 3-oxidoreductase; Cycloeucalenone + NADPH + H+ <=> Cycloeucalenol + NADP+ R12400 episterol:NADP+ 3-oxidoreductase; Episterone + NADPH + H+ <=> Episterol + NADP+ R12401 delta7-avenasterol:NADP+ 3-oxidoreductase; Avenastenone + NADPH + H+ <=> Delta7-Avenasterol + NADP+ R12402 3beta-hydroxysteroid:NADP+ 3-oxidoreductase; 3beta-Hydroxysteroid + NADP+ <=> 3-Oxosteroid + NADPH + H+ R12403 4alpha-methylzymosterol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating); 4alpha-Methylzymosterol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol + 6 Ferricytochrome b5 + 4 H2O R12404 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ 3-oxidoreductase (decarboxylating); 4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> Zymosterone + NADPH + H+ + CO2 R12405 zymosterol:NADP+ 3-oxidoreductase; Zymosterone + NADPH + H+ <=> Zymosterol + NADP+ R12406 3beta-hydroxysteroid-4alpha-carboxylate:NADP+ 3-oxidoreductase (decarboxylating); 3beta-Hydroxysteroid-4alpha-carboxylate + NADP+ <=> 3-Oxosteroid + CO2 + NADPH + H+ R12407 L-lysine,2-oxoglutarate:oxygen oxidoreductase (4-halogenating); L-Lysine + 2-Oxoglutarate + Oxygen + Cl- + H+ <=> 4-Chloro-L-lysine + Succinate + CO2 + H2O R12408 4-chloro-L-lysine,hydrogen-donor:oxygen oxidoreductase; 4-Chloro-L-lysine + Reduced acceptor + Oxygen <=> 2-Amino-4-chloro-4-pentenoic acid + Acceptor + Formaldehyde + Ammonia + H2O R12409 2-Amino-4-chloro-4-pentenoic acid <=> L-Propargylglycine + Cl- + H+ R12410 L-Propargylglycine + L-Glutamate <=> gamma-L-Glutamyl-L-propargylglycine R12411 gamma-L-glutamyl-L-propargylglycine,2-oxoglutarate:oxygen oxidoreductase; gamma-L-Glutamyl-L-propargylglycine + 2-Oxoglutarate + Oxygen <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + Succinate + CO2 R12412 L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + H2O <=> L-beta-Ethynylserine + L-Glutamate R12413 L-Tryptophan + L-Phenylalanine <=> Cyclo(L-Trp-L-Phe) R12414 S-adenosyl-L-methionine:cyclo(L-Trp-L-Phe) N-methyltransferase; Cyclo(L-Trp-L-Phe) + S-Adenosyl-L-methionine <=> N-Methyl-cyclo(L-Trp-L-Phe) + S-Adenosyl-L-homocysteine R12415 2 N-Methyl-cyclo(L-Trp-L-Phe) <=> (-)-Ditryptophenaline R12416 (9Z,12Z)-octadeca-9,12-dienoyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (15,16 cis-dehydrogenating); Linoleoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> alpha-Linolenoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O R12417 Anthranilate + L-Tryptophan + L-Alanine + 3 ATP <=> Fumiquinazoline F + 3 AMP + 3 Diphosphate + H2O R12418 Fumiquinazoline F + 3 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Fumiquinazoline F-indoline-2',3'-diol + 3 [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12419 Fumiquinazoline F-indoline-2',3'-diol + L-Alanine + ATP <=> Fumiquinazoline A + AMP + Diphosphate + H2O R12420 Fumiquinazoline A + Oxygen <=> Fumiquinazoline C + Hydrogen peroxide R12421 Fumiquinazoline C <=> Fumiquinazoline D R12422 [2Fe-2S]-ferredoxin:NADP+ oxidoreductase; 2 Reduced [2Fe-2S] ferredoxin + NADP+ + H+ <=> 2 Oxidized [2Fe-2S] ferredoxin + NADPH R12423 [lipoyl-carrier protein E2]-N6-(octanoyl)-L-lysine:[Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase; [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> Enzyme N6-(dihydrolipoyl)lysine + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin R12424 [glycine cleavage system H]-N6-octanoyl-L-lysine:[Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster sulfurtransferase; [Glycine cleavage system H]-N6-octanoyl-L-lysine + [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-Adenosyl-L-methionine + 2 Reduced [2Fe-2S] ferredoxin + 8 H+ <=> Dihydrolipoylprotein + [Fe-S] cluster scaffold protein + 2 Hydrogen sulfide + 4 Fe2+ + 2 L-Methionine + 2 5'-Deoxyadenosine + 2 Oxidized [2Fe-2S] ferredoxin R12425 [glycine cleavage system H]-N6-octanoyl-L-lysine:[lipoyl-carrier protein E2]-L-lysine octanoyltransferase; [Glycine cleavage system H]-N6-octanoyl-L-lysine + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine R12426 [glycine cleavage system H]-N6-lipoyl-L-lysine:[lipoyl-carrier protein]-L-lysine lipoyltransferase; Lipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(lipoyl)lysine R12427 octanoyl-[acp]:lipoyl-carrier-protein-E2 N-octanoyltransferase; Octanoyl-[acp] + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + Acyl-carrier protein R12428 octanoyl-[acp]:glycine-cleavage-system-H N-octanoyltransferase; Octanoyl-[acp] + Glycine cleavage system H <=> [Glycine cleavage system H]-N6-octanoyl-L-lysine + Acyl-carrier protein R12429 [lipoyl-carrier protein E2]-L-lysine:octanoate ligase (AMP-forming); ATP + Octanoic acid + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + AMP + Diphosphate R12430 octanoyl-[acp]:CoA S-octanoyltransferase; Octanoyl-[acp] + CoA <=> Octanoyl-CoA + Acyl-carrier protein R12431 octanoyl-CoA:lipoyl-carrier-protein-E2 N-octanoyltransferase; Octanoyl-CoA + Lipoyl-carrier protein E2 <=> [Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine + CoA R12432 [glycine cleavage system H]-N6-[(R)-dihydrolipoyl]-L-lysine:[lipoyl-carrier protein E2]-L-lysine dihydrolipoyltransferase; Dihydrolipoylprotein + Lipoyl-carrier protein E2 <=> Glycine cleavage system H + Enzyme N6-(dihydrolipoyl)lysine R12433 [glycine cleavage system H]-L-lysine:(R)-lipoate ligase (AMP-forming); ATP + (R)-Lipoate + Glycine cleavage system H <=> Lipoylprotein + AMP + Diphosphate R12434 ATP + Dihydrolipoate <=> Dihydrolipoyl-AMP + Diphosphate R12435 Dihydrolipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + 2 H+ R12436 L-Tryptophan + L-Histidine <=> Histidyltryptophyldiketopiperazine R12437 Histidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine D + Diphosphate R12438 Histidyltryptophyldiketopiperazine <=> Dehydrohistidyltryptophyldiketopiperazine R12439 Dehydrohistidyltryptophyldiketopiperazine + Dimethylallyl diphosphate <=> Roquefortine C + Diphosphate R12440 Roquefortine D <=> Roquefortine C R12441 Roquefortine C + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Glandicoline A + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R12442 Glandicoline A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O R12443 Glandicoline B + S-Adenosyl-L-methionine <=> Meleagrin + S-Adenosyl-L-homocysteine R12444 Roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> N1-Hydroxy-roquefortine C + [Oxidized NADPH---hemoprotein reductase] + H2O R12445 N1-Hydroxy-roquefortine C + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Roquefortine L + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12446 Roquefortine L + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Glandicoline B + [Oxidized NADPH---hemoprotein reductase] + H2O R12447 N1-Hydroxy-roquefortine C + S-Adenosyl-L-methionine <=> Roquefortine F + S-Adenosyl-L-homocysteine R12448 Roquefortine F + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Neoxaline + [Oxidized NADPH---hemoprotein reductase] + H2O R12449 [lipoyl-carrier protein E2]-L-lysine:(R)-lipoate ligase (AMP-forming); ATP + (R)-Lipoate + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP + Diphosphate R12450 Lipoyl-AMP + Lipoyl-carrier protein E2 <=> Enzyme N6-(lipoyl)lysine + AMP R12451 (hydroxymethyl)phosphonate:oxygen 1-oxidoreductase (formate-forming); Hydroxymethylphosphonate + Oxygen <=> Formate + Orthophosphate R12452 methylphosphonate,2-oxoglutarate:oxygen oxidoreductase (1-hydroxylating); Methylphosphonate + 2-Oxoglutarate + Oxygen <=> Hydroxymethylphosphonate + Succinate + CO2 R12453 cyclohexane-1-carbonyl-CoA:NADP+ 1-oxidoreductase; Cyclohexane-1-carbonyl-CoA + NADP+ <=> Cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ R12454 Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O R12455 Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O R12456 (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valerianol-forming); trans,trans-Farnesyl diphosphate + H2O <=> Valerianol + Diphosphate R12457 methanethiol:NAD+ oxidoreductase (dimethyl disulfide-forming); 2 Methanethiol + NAD+ <=> Dimethyl disulfide + NADH + H+ R12458 S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase; S-Adenosyl-L-methionine + Cycloartenol <=> S-Adenosyl-L-homocysteine + Cyclolaudenol R12459 protein N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6,N6,N6-trimethyl-L-lysine + 2 2-Oxoglutarate + 2 Oxygen <=> Protein N6-methyl-L-lysine + 2 Succinate + 2 Formaldehyde + 2 CO2 R12460 protein N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6,N6,N6-trimethyl-L-lysine + 2-Oxoglutarate + Oxygen <=> Protein N6,N6-dimethyl-L-lysine + Succinate + Formaldehyde + CO2 R12461 protein N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase; Protein N6,N6,N6-trimethyl-L-lysine + 3 2-Oxoglutarate + 3 Oxygen <=> Protein lysine + 3 Succinate + 3 Formaldehyde + 3 CO2 R12462 protein-N6,N6-dimethyl-L-lysine:acceptor oxidoreductase (demethylating); Protein N6,N6-dimethyl-L-lysine + 2 Acceptor + 2 H2O <=> Protein lysine + 2 Formaldehyde + 2 Reduced acceptor R12463 protein-N6,N6-dimethyl-L-lysine:acceptor oxidoreductase (demethylating); Protein N6,N6-dimethyl-L-lysine + Acceptor + H2O <=> Protein N6-methyl-L-lysine + Formaldehyde + Reduced acceptor R12464 protein N6-methyl-L-lysine:acceptor oxidoreductase (demethylating); Protein N6-methyl-L-lysine + Acceptor + H2O <=> Protein lysine + Formaldehyde + Reduced acceptor R12465 stearoyl-CoA:2-O-sulfo-alpha,alpha-trehalose 2'-stearoyltransferase; Stearoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-stearoyl-alpha,alpha-trehalose + CoA R12466 palmitoyl-CoA:2-O-sulfo-alpha,alpha-trehalose 2'-palmitoyltransferase; Palmitoyl-CoA + 2-Sulfotrehalose <=> 2-O-Sulfo-2'-palmitoyl-alpha,alpha-trehalose + CoA R12467 malonyl-CoA/(S)-methylmalonyl-CoA:4-nitrobenzoyl-CoA (methyl)malonyltransferase (demethylluteothin-forming); 4-Nitrobenzoyl-CoA + Malonyl-CoA + 4 (S)-Methylmalonyl-CoA + 4 NADPH + 4 H+ <=> Demethylluteothin + 5 CO2 + 6 CoA + 4 NADP+ + 3 H2O R12468 malonyl-CoA/(S)-methylmalonyl-CoA:4-nitrobenzoyl-CoA (methyl)malonyltransferase (demethyldeoxyspectinabilin-forming); 4-Nitrobenzoyl-CoA + Malonyl-CoA + 6 (S)-Methylmalonyl-CoA + 6 NADPH + 6 H+ <=> Demethyldeoxyspectinabilin + 7 CO2 + 8 CoA + 6 NADP+ + 5 H2O R12469 UDP-alpha-D-glucose:enterobactin 5'-C-beta-D-glucosyltransferase (configuration-inverting); UDP-glucose + Enterochelin <=> UDP + Monoglucosyl-enterobactin R12470 UDP-alpha-D-glucose:monoglucosyl-enterobactin 5'-C-beta-D-glucosyltransferase (configuration-inverting); UDP-glucose + Monoglucosyl-enterobactin <=> UDP + Diglucosyl-enterobactin R12471 UDP-alpha-D-glucose:diglucosyl-enterobactin 5'-C-beta-D-glucosyltransferase (configuration-inverting); UDP-glucose + Diglucosyl-enterobactin <=> UDP + Triglucosyl-enterobactin R12472 GDP-alpha-D-mannose:inositol phospho-(2'R)-2'-hydroxyphytoceramide mannosyltransferase; GDP-mannose + Very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide <=> Very-long-chain mannosylinositol phospho-(2'R)-2'-hydroxyphytoceramide + GDP R12473 apo-salmochelin esterase; Enterochelin + H2O <=> N-(2,3-Dihydroxybenzoyl)-L-serine trimer R12474 apo-triglucosyl-salmochelin esterase; Triglucosyl-enterobactin + H2O <=> Triglucosyl-(2,3-dihydroxybenzoylserine)3 R12475 apo-diglucosyl-salmochelin esterase; Diglucosyl-enterobactin + H2O <=> Diglucosyl-(2,3-dihydroxybenzoylserine)3 R12476 apo-monoglucosyl-salmochelin esterase; Monoglucosyl-enterobactin + H2O <=> Monoglucosyl-(2,3-dihydroxybenzoylserine)3 R12477 Man9GlcNAc2-[protein]2-alpha-mannohydrolase (configuration-inverting); G00374 + H2O <=> G00272 + D-Mannose R12478 Nalpha-acyl-L-glutamine amidohydrolase (carboxylate-forming); N-Acyl-L-glutamine + H2O <=> L-Glutamine + Carboxylate R12479 G10694 + 3 H2O <=> G00012 + 3 D-Mannose R12481 Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n R12482 UDP-D-glucuronate + Thomsen-Friedenreich antigen <=> UDP + Glucuronylated core 1 glycans (linear) R12483 nepetalactol:NAD+ 1-oxidoreductase; (+)-cis,cis-Nepetalactol + NAD+ <=> (+)-cis,cis-Nepetalactone + NADH + H+ R12484 nepetalactol:NAD+ 1-oxidoreductase; cis-trans-Nepetalactol + NAD+ <=> Nepetalactone cis-trans-form + NADH + H+ R12485 isophthalate:CoA ligase (AMP-forming); ATP + Isophthalate + CoA <=> AMP + Diphosphate + Isophthalyl-CoA R12486 isophthalyl-CoA carboxy-lyase; Isophthalyl-CoA <=> Benzoyl-CoA + CO2 R12487 (R)-3-(aryl)lactoyl-CoA hydro-lyase; (R)-Phenyllactyl-CoA <=> (E)-Cinnamoyl-CoA + H2O R12488 (R)-3-(aryl)lactoyl-CoA hydro-lyase; (R)-3-(4-Hydroxyphenyl)lactoyl-CoA <=> p-Coumaroyl-CoA + H2O R12489 (R)-3-(aryl)lactoyl-CoA hydro-lyase; (R)-3-(Indol-3-yl)lactoyl-CoA <=> 3-(Indol-3-yl)acryloyl-CoA + H2O R12490 pre-sodorifen diphosphate-lyase [sodorifen-forming]; Pre-sodorifen diphosphate <=> Sodorifen + Diphosphate R12491 4-amino-4-deoxychorismate pyruvatemutase; 4-Amino-4-deoxychorismate <=> 4-Amino-4-deoxyprephenate R12492 (E)-4-coumaroyl-CoA:(R)-3-(4-hydroxyphenyl)lactate CoA-transferase; p-Coumaroyl-CoA + (R)-3-(4-Hydroxyphenyl)lactate <=> 4-Coumarate + (R)-3-(4-Hydroxyphenyl)lactoyl-CoA R12493 3-(indol-3-yl)acryloyl-CoA:(R)-3-(indol-3-yl)lactate CoA-transferase; 3-(Indol-3-yl)acryloyl-CoA + (R)-(Indol-3-yl)lactate <=> 3-Indoleacrylate + (R)-3-(Indol-3-yl)lactoyl-CoA R12494 marinolic acid:CoA ligase (AMP-forming); ATP + Marinolic acid <=> AMP + Diphosphate + Marinoloyl-CoA R12495 marinolic acid:CoA ligase (AMP-forming); ATP + Pseudomonic acid <=> AMP + Diphosphate + Pseudomonoyl-CoA R12496 long-chain acyl-CoA:sterol O-acyltransferase; Long-chain acyl-CoA + Sterol <=> CoA + Long-chain 3-hydroxysterol ester R12497 S-adenosyl-L-methionine:cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} C-methyltransferase; 2 S-Adenosyl-L-methionine + Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Reduced acceptor <=> S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + Acceptor R12498 2-Hydroxyethylphosphonate + CTP <=> Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Diphosphate R12499 Cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O <=> (S)-2-Hydroxypropylphosphonate + CMP R12500 queuosine34 in tRNA:acceptor oxidoreductase; tRNA queuine + Acceptor + H2O <=> Epoxyqueuosine in tRNA + Reduced acceptor R12501 Indole-3-acetate + 2-Oxoglutarate + Oxygen <=> 2-Oxoindole-3-acetate + Succinate + CO2 R12502 D-apiofuranose:NAD+ 1-oxidoreductase; D-Apiofuranose + NAD+ <=> D-Apionolactone + NADH + H+ R12503 D-apionate:NAD+ oxidoreductase (isomerizing); D-Apionate + NAD+ <=> 3-Oxoisoapionate + NADH + H+ R12504 phenylacetate carboxy-lyase; Phenylacetic acid <=> Toluene + CO2 R12505 hydrogen sulfide:L-aspartate-4-semialdehyde sulfurtransferase; Hydrogen sulfide + L-Aspartate 4-semialdehyde + 2 Reduced ferredoxin + 2 H+ <=> L-Homocysteine + H2O + 2 Oxidized ferredoxin R12506 L-arginine:L-lysine amidinotransferase; L-Arginine + L-Lysine <=> L-Ornithine + Homoarginine R12507 L-glutamine:4-(methylsulfanyl)-2-oxobutanoate aminotransferase; L-Glutamine + 4-Methylthio-2-oxobutanoic acid <=> 2-Oxoglutaramate + L-Methionine R12508 ubiquinol:oxygen oxidoreductase (superoxide-forming); 2 Oxygen + Ubiquinol <=> 2 Superoxide + Ubiquinone + 2 H+ R12509 7-deoxycylindrospermopsin,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating); 7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> Cylindrospermopsin + Succinate + CO2 R12510 7-deoxycylindrospermopsin,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating); 7-Deoxycylindrospermopsin + 2-Oxoglutarate + Oxygen <=> 7-epi-Cylindrospermopsin + Succinate + CO2 R12511 L-proline betaine,NADH:oxygen oxidoreductase (formaldehyde-forming); Stachydrine + NADH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NAD+ + H2O R12512 L-proline betaine,NADPH:oxygen oxidoreductase (formaldehyde-forming); Stachydrine + NADPH + H+ + Oxygen <=> N-Methyl-L-proline + Formaldehyde + NADP+ + H2O R12513 (indol-3-yl)acetyl-L-aspartate amidohydrolase; (Indol-3-yl)acetyl-L-aspartate + H2O <=> Indole-3-acetate + L-Aspartate R12514 cysteinylglycine-S-conjugate dipeptide hydrolase; R-S-Cysteinylglycine + H2O <=> L-Cysteine-S-conjugate + Glycine R12515 ethyl acetate acetohydrolase; Ethyl acetate + H2O <=> Acetate + Ethanol R12516 3-methylbutyl acetate acetohydrolase; Isoamyl acetate + H2O <=> 3-Methylbutanol + Acetate R12517 (S)-8-oxocitronellyl enol:NAD+ oxidoreductase; (6E)-8-Oxogeranial + NADH + H+ <=> (S)-8-Oxocitronellyl enol + NAD+ R12518 (S)-8-oxocitronellyl enol:NADP+ oxidoreductase; (6E)-8-Oxogeranial + NADPH + H+ <=> (S)-8-Oxocitronellyl enol + NADP+ R12519 (R)-8-oxocitronellyl enol:NADP+ oxidoreductase; (6E)-8-Oxogeranial + NADPH + H+ <=> (R)-8-Oxocitronellyl enol + NADP+ R12520 (S)-8-oxocitronellyl enol cyclase [(+)-cis,trans-nepetalactol-forming]; (S)-8-Oxocitronellyl enol <=> cis-trans-Nepetalactol R12521 (S)-8-oxocitronellyl enol cyclase [(+)-cis,cis-nepetalactol-forming]; (S)-8-Oxocitronellyl enol <=> (+)-cis,cis-Nepetalactol R12522 (+)-(1S,2S)-pseudoephedrine:NAD+ 1-oxoreductase; (+)-(1S,2S)-Pseudoephedrine + NAD+ <=> (S)-2-Methylamino-1-phenylpropan-1-one + NADH + H+ R12523 4-amino-4-deoxyprephenate:NAD+ oxidoreductase (decarboxylating); 4-Amino-4-deoxyprephenate + NAD+ <=> 3-(4-Aminophenyl)pyruvate + NADH + CO2 + H+ R12524 (2E,6E)-farnesyl diphosphate 10-C-methyltransferase (cyclyzing, pre-sodorifen diphosphate producing); S-Adenosyl-L-methionine + trans,trans-Farnesyl diphosphate <=> S-Adenosyl-L-homocysteine + Pre-sodorifen diphosphate R12525 GDP-alpha-D-mannose:[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol 2-alpha-mannosyltransferase (configuration-retaining); 2 GDP-mannose + [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R12526 GDP-alpha-D-mannose:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase (configuration-retaining); 2 GDP-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol <=> 2 GDP + [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol R12527 sucrose:(1->3)-alpha-D-glucan 3-alpha-D-glucosyltransferase; Sucrose + 1,3-alpha-D-Glucan(n) <=> D-Fructose + 1,3-alpha-D-Glucan(n+1) R12528 sucrose:(1->6)-alpha-D-glucan 2-alpha-D-glucosyl-transferase; Sucrose + Dextran <=> D-Fructose + (1->6)-alpha-D-Glucan containing a (1->2)-alpha-D-glucose branch R12529 DP-alpha-D-mannose:(1->2)-beta-D-mannan mannosyltransferase (configuration-inverting); GDP-mannose + 1,2-beta-Oligomannan(n) <=> GDP + 1,2-beta-Oligomannan(n+1) R12530 ATP:amicoumacin A 2-phosphotransferase; ATP + Amicoumacin A <=> ADP + Amicoumacin A 2-phosphate R12531 amicoumacin 2-phosphate phosphohydrolase; Amicoumacin A 2-phosphate + H2O <=> Amicoumacin A + Orthophosphate R12532 8-oxo-GTP diphosphohydrolase; 8-Oxo-GTP + H2O <=> 8-Oxo-GDP + Orthophosphate R12533 8-oxo-dGTP diphosphohydrolase; 8-Oxo-dGTP + H2O <=> 8-Oxo-dGDP + Orthophosphate R12534 phloretate:electron-transfer flavoprotein 2,3-oxidoreductase; Phloretate + Electron-transferring flavoprotein <=> 4-Coumarate + Reduced electron-transferring flavoprotein R12535 3-(phenyl)propanoate:electron-transfer flavoprotein 2,3-oxidoreductase; Phenylpropanoate + Electron-transferring flavoprotein <=> trans-Cinnamate + Reduced electron-transferring flavoprotein R12536 3-(1H-indol-3-yl)propanoate:electron-transfer flavoprotein 2,3-oxidoreductase; 3-(1H-Indol-3-yl)propanoate + Electron-transferring flavoprotein <=> 3-Indoleacrylate + Reduced electron-transferring flavoprotein R12537 3-sn-phosphatidyl-L-serine sn-1 acylhydrolase; 1-Acyl-sn-glycero-3-phosphoserine + H2O <=> Glycerophosphoserine + Fatty acid R12538 Dibenzothiophene-5,5-dioxide + FMN-N5-peroxide <=> 2'-Hydroxybiphenyl-2-sulfinate + FMN-N5-oxide R12539 FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+ R12540 L-phenylalanine,tetrahydropteridine:oxygen oxidoreductase (4-hydroxylating); L-Phenylalanine + Tetrahydropteridine + Oxygen <=> L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R12541 L-tyrosine,tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating); L-Tyrosine + Tetrahydropteridine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R12542 L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating); L-Tryptophan + Tetrahydropteridine + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R12543 L-phenylalanine,tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating); L-Phenylalanine + Tetrahydropteridine + Oxygen <=> 3-Hydroxy-L-phenylalanine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R12544 uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening); Uracil + Reduced FMN + Oxygen + NADH <=> Ureidoacrylate + H2O + FMN + NAD+ + H+ R12545 Uracil + FMN-N5-peroxide <=> Ureidoacrylate + FMN-N5-oxide R12546 thymine,FMNH2:oxygen oxidoreductase (thymine hydroxylating, ring-opening); Thymine + Reduced FMN + Oxygen + NADH <=> Methylureidoacrylate + H2O + FMN + NAD+ + H+ R12547 Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide R12548 5,10-methylenetetrahydrofolate:tRNA (uracil54-C5)-methyltransferase; 5,10-Methylenetetrahydrofolate + tRNA containing uridine at position 54 + NADH + H+ <=> Tetrahydrofolate + tRNA containing ribothymidine at position 54 + NAD+ R12549 Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-D-glucose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose R12550 chenodeoxycholate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating); Chenodeoxycholate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cholic acid + [Oxidized NADPH---hemoprotein reductase] + H2O R12551 UDP-2-acetamido-2,6-dideoxy-beta-L-mannose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-glucose R12552 UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ R12553 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose R12554 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose <=> UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose R12555 UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-galactose R12556 UDP-N-acetyl-alpha-D-quinovosamine:NADP+ 4-dehydrogenase; UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NADP+ R12557 UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + D-Alanine <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose + H2O R12558 UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-glucopyranose <=> UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose R12559 UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose + H2O <=> 2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + UDP R12560 (-)-(1R,2S)-ephedrine:NAD+ 1-oxoreductase; Ephedrine + NAD+ <=> (S)-2-Methylamino-1-phenylpropan-1-one + NADH + H+ R12561 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + Acetyl-CoA <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose + CoA R12562 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + CTP <=> CMP-5-N-acetyl-7-N-(D-alanyl)-legionaminic acid + Diphosphate R12563 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose R12564 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose + H2O <=> 2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + UDP R12565 2,4-Diacetamido-2,4,6-trideoxy-beta-L-gulose + Phosphoenolpyruvate + H2O <=> 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Orthophosphate R12566 feruloyl-CoA hydro-lyase/vanillin-lyase (acetyl-CoA-forming); Feruloyl-CoA + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA R12567 2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate R12568 CTP + 5,7-Diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid <=> CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonic acid + Diphosphate R12569 [sulfatase]-L-serine:S-adenosyl-L-methionine oxidoreductase (3-oxo-L-alanine-forming); [Sulfatase]-L-serine + S-Adenosyl-L-methionine <=> [Sulfatase]-3-oxo-L-alanine + 5'-Deoxyadenosine + L-Methionine R12570 thioredoxin:hydroperoxide oxidoreductase; Thioredoxin + ROOH <=> Thioredoxin disulfide + H2O + ROH R12571 glutaredoxin:hydroperoxide oxidoreductase; Glutaredoxin + ROOH <=> Glutaredoxin disulfide + H2O + ROH R12572 ATP + L-Arginine <=> Diphosphate + (L-Arginyl)adenylate R12573 L-arginine:[L-arginyl-carrier protein] ligase (AMP-forming); L-Arginine + Peptidyl-carrier protein + ATP <=> L-Arginyl-[pcp] + AMP + Diphosphate R12574 (L-Arginyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Arginyl-[pcp] R12575 ATP + 3,4-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] R12576 ATP + 3,4-Dihydroxybenzoate <=> Diphosphate + (3,4-Dihydroxybenzoyl)adenylate R12577 (3,4-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] R12578 glutathione:hydroperoxide oxidoreductase; 2 Glutathione + ROOH <=> Glutathione disulfide + H2O + ROH R12579 NADH:hydroperoxide oxidoreductase; NADH + ROOH + H+ <=> NAD+ + H2O + ROH R12580 geranyl diphosphate/selenophosphate:tRNA 5-methylaminomethyl-2-thiouridine34 geranyl/selenophosphatetransferase; Selenophosphoric acid + Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate + H2O <=> 5-Methylaminomethyl-2-selenouridine in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol + Diphosphate + Orthophosphate R12581 geranyl diphosphate:tRNA 5-methylaminomethyl-2-thiouridine34 geranyltransferase; Geranyl diphosphate + tRNA containing 5-[(methylamino)methyl]-2-thiouridylate <=> 5-Methylaminomethyl-2-(S-geranyl)thiouridine in tRNA + Diphosphate R12582 selenophosphate:5-methylaminomethyl-2-(S-geranyl)thiouridine34 selenophosphatetransferase; Selenophosphoric acid + 5-Methylaminomethyl-2-(S-geranyl)thiouridine in tRNA <=> 5-Methylaminomethyl-2-(Se-phospho)selenouridine in tRNA + (2E)-3,7-Dimethylocta-2,6-diene-1-thiol R12583 5-methylaminomethyl-2-(Se-phospho)selenouridine34 phosphohydrolase; 5-Methylaminomethyl-2-(Se-phospho)selenouridine in tRNA + H2O <=> 5-Methylaminomethyl-2-selenouridine in tRNA + Orthophosphate R12584 UDP-N-acetyl-beta-L-fucosamine <=> UDP-2,6-dideoxy-2-acetamidino-beta-L-galactose R12585 2-hydroxy fatty acid:oxygen oxidoreductase (CO2,H2O-forming); (2R)-2-Hydroxy fatty acid + Oxygen <=> Fatty acid + H2O + CO2 R12586 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate <=> UDP-2,3-dideoxy-2-acetamido-3-acetamidino-alpha-D-mannuronic acid R12587 NADPH 2'-phosphohydrolase; NADPH + H2O <=> NADH + Orthophosphate R12588 S-inosyl-L-homocysteine hydrolase (inosine-forming); S-Inosyl-L-homocysteine + H2O <=> Inosine + L-Homocysteine R12589 xanthosine 5'-triphosphate phosphohydrolase; XTP + H2O <=> XDP + Orthophosphate R12590 UDP-N-acetyl-D-galactosaminuronic acid + ATP + L-Glutamine + H2O <=> UDP-2-acetamido-2-deoxy-alpha-D-galacturonamide + AMP + L-Glutamate + Diphosphate R12591 limonene:acceptor oxidoreductase (7-hydroxylating); (S)-Limonene + H2O + Acceptor <=> (-)-Perillyl alcohol + Reduced acceptor R12592 limonene:acceptor oxidoreductase (7-hydroxylating); (R)-Limonene + H2O + Acceptor <=> (+)-Perillyl alcohol + Reduced acceptor R12593 1-alkyl-sn-glycerol,tetrahydrobiopteridine:oxygen oxidoreductase; 1-Alkyl-sn-glycerol + Tetrahydropteridine + Oxygen <=> 1-Hydroxyalkyl-sn-glycerol + 4a-Hydroxy-5,6,7,8-tetrahydropteridine R12594 ADP:D-glucosamine 6-phosphotransferase; ADP + D-Glucosamine <=> AMP + D-Glucosamine 6-phosphate R12595 8-oxo-GDP phosphohydrolase; 8-Oxo-GDP + H2O <=> 8-Oxo-GMP + Orthophosphate R12596 Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate R12597 N-Citryl-spermidine + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Aryl-carrier protein R12598 N-Citryl-spermidine + Spermidine + ATP <=> N8,N'8-Citryl-bis(spermidine) + AMP + Diphosphate R12599 N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine + Spermidine + ATP <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + AMP + Diphosphate R12600 N8,N'8-Citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + Aryl-carrier protein R12601 N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) + 3,4-Dihydroxybenzoyl-[aryl-carrier protein] <=> Petrobactin + Aryl-carrier protein R12602 lipoyl:hydroperoxide oxidoreductase; [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine + ROOH <=> Protein N6-(lipoyl)lysine + H2O + ROH R12603 lipoyl:hydroperoxide oxidoreductase; Enzyme N6-(dihydrolipoyl)lysine + ROOH <=> Enzyme N6-(lipoyl)lysine + H2O + ROH R12604 UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+ R12605 Protoporphyrinogen IX + 3 Acceptor <=> Protoporphyrin + 3 Reduced acceptor R12606 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate <=> UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + 2-Oxoglutarate R12607 GDP-alpha-D-glucose:hexose 1-phosphate guanylyltransferase; GDP-glucose + D-Mannose 1-phosphate <=> D-Glucose 1-phosphate + GDP-mannose R12608 GTP:3'-dephospho-CoA 3'-phosphotransferase; GTP + Dephospho-CoA <=> GDP + CoA R12609 3-oxoisoapionate carboxy-lyase; 3-Oxoisoapionate <=> L-Erythrulose + CO2 R12610 3-oxoisoapionate 4-phosphate carboxy-lyase; 3-Oxoisoapionate 4-phosphate <=> Erythrulose 1-phosphate + CO2 R12611 L-tyrosine:hydrogen-peroxide oxidoreductase (L-dopa-forming); L-Tyrosine + Hydrogen peroxide <=> 3,4-Dihydroxy-L-phenylalanine + H2O R12612 5-deoxy-D-ribulose 1-phosphate acetaldehyde-lyase (glycerone-phosphate-forming); 5-Deoxy-D-ribulose 1-phosphate <=> Glycerone phosphate + Acetaldehyde R12613 S-methyl-5-thio-D-ribulose 1-phosphate acetaldehyde-lyase (glycerone-phosphate-forming); S-Methyl-5-thio-D-ribulose 1-phosphate <=> Glycerone phosphate + (2-Methylthio)acetaldehyde R12614 [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate:oxygen 1R-oxidoreductase (glycine-betaine-forming); [(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Oxygen <=> Betaine + Orthophosphate R12615 [2-(trimethylamino)ethyl]phosphonate,2-oxoglutarate:oxygen oxidoreductase (1R-hydroxylating); [2-(Trimethylamino)ethyl]phosphonate + 2-Oxoglutarate + Oxygen <=> [(1R)-1-Hydroxy-2-(trimethylamino)ethyl]phosphonate + Succinate + CO2 R12616 ATP:3-oxoisoapionate 4-phosphotransferase; ATP + 3-Oxoisoapionate <=> ADP + 3-Oxoisoapionate 4-phosphate R12617 3,5,6-trichloropyridin-2-ol,FADH2:oxygen oxidoreductase (dechlorinating); 3,5,6-Trichloropyridin-2-ol + FADH2 + Oxygen <=> 3,6-Dichloropyridine-2,5-dione + Cl- + FAD + H2O R12618 3,6-dichloropyridine-2,5-diol,FADH2:oxygen oxidoreductase (dechlorinating); 3,6-Dichloropyridine-2,5-diol + FADH2 + Oxygen <=> 6-Chloro-3-hydroxypyridine-2,5-dione + Cl- + FAD + H2O R12619 6-chloropyridine-2,3,5-triol,FADH2:oxygen oxidoreductase (dechlorinating); 6-Chloropyridine-2,3,5-triol + FADH2 + Oxygen <=> 3,6-Dihydroxypyridine-2,5-dione + Cl- + FAD + H2O R12620 (2E)-2-enoyl-CoA:NADP+ 4-oxidoreductase; trans-2,3-Dehydroacyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+ R12621 5'-deoxyadenosine ribohydrolase; 5'-Deoxyadenosine + H2O <=> 5-Deoxy-D-ribose + Adenine R12622 L-alanine:vanillin aminotransferase; 4-Hydroxy-3-methoxy-benzaldehyde + L-Alanine <=> Vanillylamine + Pyruvate R12623 (Z)-2-methylureidoacrylate amidohydrolase; Methylureidoacrylate + H2O <=> Methylaminoacrylate + CO2 + Ammonia R12624 Methylureidoacrylate + H2O <=> Methylaminoacrylate + Carbamate R12625 (Z)-3-ureidoacrylate amidohydrolase; Ureidoacrylate + H2O <=> Aminoacrylate + CO2 + Ammonia R12626 (6E)-8-methylnon-6-enoyl-CoA:vanillylamine 8-methylnon-6-enoyltranferase; (6E)-8-Methylnon-6-enoyl-CoA + Vanillylamine <=> Capsaicin + CoA R12628 8-Methyl-6-nonenoic acid <=> (6E)-8-Methylnon-6-enoyl-CoA R12629 (3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase; (3E)-3-Enoyl-CoA + NADP+ <=> (2E,4E)-2,4-Dienoyl-CoA + NADPH + H+ R12630 (3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase; (3E)-3-Enoyl-CoA + NADP+ <=> (2E,4Z)-2,4-Dienoyl-CoA + NADPH + H+ R12631 thiocyanate:cytochrome c oxidoreductase (cyanate and sulfur-forming); Thiocyanate + 2 Ferricytochrome c + H2O <=> Cyanate + Sulfur + 2 Ferrocytochrome c + H+ R12632 S-adenosyl-L-methionine:3,3'-di-O-methyl-4alpha-mannobiose 1-O-methyltransferase; S-Adenosyl-L-methionine + 3,3'-Di-O-methyl-4alpha-mannobiose <=> S-Adenosyl-L-homocysteine + 1,3,3'-Tri-O-methyl-4alpha-mannobiose R12633 ADP:polyphosphate phosphotransferase; ADP + Polyphosphate <=> AMP + Polyphosphate R12634 exo (1->2)-beta-D-glucooligosaccharide sophorohydrolase (non-reducing end); 1,2-beta-D-Glucan + H2O <=> Sophorose + 1,2-beta-D-Glucan R12635 N4-acetylcytidine amidohydrolase; N4-Acetylcytidine + H2O <=> Cytidine + Acetate R12636 CMP-N-acetylneuraminate:N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminide N-acetyl-beta-D-glucosamine-6-alpha-N-acetylneuraminyltransferase (configuration-inverting); CMP-N-acetylneuraminate + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R <=> CMP + N-Acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-R R12637 UDP-alpha-D-xylose:[EGF-like domain protein]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine 3-alpha-D-xylosyltransferase (configuration-retaining); UDP-D-xylose + G03532 <=> UDP + G10913 R12638 Neryl diphosphate + Isopentenyl diphosphate <=> Diphosphate + 2-cis,6-cis-Farnesyl diphosphate R12639 2-cis,6-cis-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Nerylneryl diphosphate R12640 salicylate:CoA ligase (AMP-forming); ATP + Salicylate <=> (Salicyl)adenylate + Diphosphate R12641 salicylate:CoA ligase (AMP-forming); (Salicyl)adenylate + CoA <=> AMP + 2-Hydroxybenzoyl-CoA R12642 salicylate:CoA ligase (AMP-forming); ATP + Salicylate + CoA <=> AMP + Diphosphate + 2-Hydroxybenzoyl-CoA R12643 D-xylose:NADP+ 1-oxidoreductase (D-xylono-1,4-lactone-forming); D-Xylose + NADP+ <=> D-Xylono-1,4-lactone + NADPH + H+ R12644 7,8-dihydrobiopterin:NADP+ oxidoreductase; 7,8-Dihydrobiopterin + NADP+ <=> Biopterin + NADPH + H+ R12645 [protein]-L-arginine,2-oxoglutarate:oxygen oxidoreductase (3R-hydroxylating); Protein-L-arginine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3R)-3-hydroxy-L-arginine + Succinate + CO2 R12646 GTP:phosphoenolpyruvate guanylyltransferase; Phosphoenolpyruvate + GTP <=> Enolpyruvoyl-2-diphospho-5'-guanosine + Diphosphate R12647 GTP:3-phospho-D-glycerate guanylyltransferase; 3-Phospho-D-glycerate + GTP <=> 3-(D-Glyceryl)-diphospho-5'-guanosine + Diphosphate R12648 enolpyruvoyl-2-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phosphoenolpyruvate transferase; Enolpyruvoyl-2-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + Dehydro coenzyme F420-0 R12649 3-[(R)-glyceryl]-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 3-phosphoglycerate transferase; 3-(D-Glyceryl)-diphospho-5'-guanosine + 7,8-Didemethyl-8-hydroxy-5-deazariboflavin <=> GMP + 3PG-factor 420-0 R12650 L-isoleucine,2-oxoglutarate:oxygen oxidoreductase (31-hydroxylating); L-Isoleucine + 2-Oxoglutarate + Oxygen <=> 3(1)-Hydroxy-L-isoleucine + Succinate + CO2 R12651 31-hydroxy-L-isoleucine,2-oxoglutarate:oxygen oxidoreductase (4S-hydroxylating); 3(1)-Hydroxy-L-isoleucine + 2-Oxoglutarate + Oxygen <=> (4S)-31,4-Dihydroxy-L-isoleucine + Succinate + CO2 R12652 abieta-8,11,13-triene,[reduced NADPH---hemoprotein reductase]:oxygen 12-oxidoreductase (ferruginol-forming); Abieta-8,11,13-triene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Ferruginol + [Oxidized NADPH---hemoprotein reductase] + H2O R12653 (+)-pinoresinol:azurin oxidoreductase; (+)-Pinoresinol + 2 Oxidized azurin + H2O <=> (+)-6-Hydroxypinoresinol + 2 Reduced azurin + 2 H+ R12657 S-adenosyl-L-methionine:3-demethylubiquinol 3-O-methyltransferase; S-Adenosyl-L-methionine + 3-Demethylubiquinol <=> S-Adenosyl-L-homocysteine + Ubiquinol R12658 2-Polyprenyl-6-methoxyphenol + Oxygen <=> 2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + H2O R12659 tryptamine,NADPH---hemoprotein reductase:oxygen oxidoreductase (5-hydroxylating); Tryptamine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serotonin + [Oxidized NADPH---hemoprotein reductase] + H2O R12660 3 Malonyl-CoA + 5 Methylmalonyl-CoA + 7 NADPH + 7 H+ <=> Protomycinolide IV + 8 CoA + 8 CO2 + 4 H2O + 7 NADP+ R12661 1-phospho-alpha-D-galacturonate phosphohydrolase; 1-Phospho-alpha-D-galacturonate + H2O <=> D-Galacturonate + Orthophosphate R12662 3-sulfanylpropanoate:oxygen oxidoreductase; 3-Sulfanylpropanoate + Oxygen <=> 3-Sulfinopropanoate R12663 L-glutamate,2-oxoglutarate:oxygen oxidoreductase (3R-hydroxylating); L-Glutamate + 2-Oxoglutarate + Oxygen <=> (3R)-3-Hydroxy-L-glutamate + Succinate + CO2 R12664 beta-D-mannopyranose 2-epimerase; beta-D-Mannose <=> beta-D-Glucose R12665 D-apiose isomerase; D-Apiose <=> Apulose R12666 S-adenosyl-L-methionine:(2R)-2-hydroxy-4-(methylsulfanyl)butanoate S-methyltransferase; S-Adenosyl-L-methionine + (2R)-2-Hydroxy-4-(methylsulfanyl)butanoate <=> S-Adenosyl-L-homocysteine + (2R)-4-(Dimethylsulfaniumyl)-2-hydroxybutanoate R12667 S-adenosyl-L-methionine:2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase; S-Adenosyl-L-methionine + 2-Heptyl-4-hydroxyquinoline-N-oxide <=> S-Adenosyl-L-homocysteine + 2-Heptyl-1-methoxyquinolin-4(1H)-one R12668 apulose-4-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; Apulose 4-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + Glycerone phosphate R12669 tuberculosinyl diphosphate:adenosine tuberculosinyltransferase; Tuberculosinyl diphosphate + Adenosine <=> 1-Tuberculosinyladenosine + Diphosphate R12670 D-apionolactone lactonohydrolase; D-Apionolactone + H2O <=> D-Apionate R12671 N,N'-diacetylchitobiose non-reducing end acetylhydrolase; Chitobiose + H2O <=> beta-D-Glucosaminyl-(1->4)-N-acetyl-D-glucosamine + Acetate R12672 neryl-diphosphate diphosphohydrolase; Neryl diphosphate + H2O <=> Nerol + Diphosphate R12673 N,N-dimethyl-N'-phenylurea compound,NAD(P)H:oxygen oxidoreductase (formaldehyde-forming); N,N-Dimethyl-N'-phenylurea compound + Reduced ferredoxin + Oxygen + H+ <=> N-Methyl-N'-phenylurea compound + Oxidized ferredoxin + Formaldehyde + H2O R12674 alpha-N-dichloroacetyl-p-aminophenylserinol,acceptor:oxygen oxidoreductase (N-hydroxylating); alpha-N-Dichloroacetyl-p-aminophenylserinol + Reduced acceptor + 2 Oxygen <=> Chloramphenicol + Acceptor + 2 H2O R12675 4-aminobenzoate,acceptor:oxygen oxidoreductase (N-hydroxylating); 4-Aminobenzoate + Reduced acceptor + 2 Oxygen <=> 4-Nitrobenzoate + Acceptor + 2 H2O R12676 tRNA N6-(3-methylbut-2-en-1-yl)-2-(methylsulfanyl)adenosine37,donor:oxygen 4-oxidoreductase (trans-hydroxylating); 2-Methylthio-N6-dimethylallyladenine in tRNA + Reduced acceptor + Oxygen <=> N6-[(2E)-4-Hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenine in tRNA + Acceptor + H2O R12677 cholest-4-en-3-one:acceptor oxidoreductase (25-hydroxylating); Cholest-4-en-3-one + Acceptor + H2O <=> 25-Hydroxycholest-4-en-3-one + Reduced acceptor R12678 3-oxo-Delta1-steroid:acceptor 1-oxidoreductase; 3-Oxo-Delta1-steroid + Acceptor + H2O <=> Steroid 1,3-dione + Reduced acceptor R12679 3-Oxo-Delta1-steroid + H2O <=> 1-Hydroxy-3-oxo-steroid R12680 1-Hydroxy-3-oxo-steroid + Acceptor <=> Steroid 1,3-dione + Reduced acceptor R12682 Heme I + Acceptor + H2O <=> Hydroxyheme I + Reduced acceptor R12683 Hydroxyheme I <=> Heme A + H2O R12684 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one:oxygen oxidoreductase; 3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia + Hydrogen peroxide R12685 3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + Oxygen <=> 5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + Hydrogen peroxide R12686 5-[(4-Hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O <=> 5-[(4-Hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + Ammonia R12687 C22972 + H2O <=> C22966 + Hexadecanoic acid R12688 L-kynurenine:2-oxoglutarate aminotransferase; L-Kynurenine + 2-Oxoglutarate <=> 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O R12689 Mercaptopyruvate + [Protein]-L-cysteine <=> Pyruvate + [Protein]-S-sulfanyl-L-cysteine R12690 [Protein]-S-sulfanyl-L-cysteine + Thioredoxin <=> Hydrogen sulfide + [Protein]-L-cysteine + Thioredoxin disulfide R12691 [Glycine cleavage system H]-N6-octanoyl-L-lysine <=> Dihydrolipoylprotein R12692 L-kynurenine:glyoxylate aminotransferase (cyclizing); L-Kynurenine + Glyoxylate <=> 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O R12693 3-hydroxy-L-kynurenine:glyoxylate aminotransferase (cyclizing); 3-Hydroxy-L-kynurenine + Glyoxylate <=> Xanthurenic acid + Glycine + H2O R12694 3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine R12695 ATP:D-ribulose 1-phosphotransferase; ATP + D-Ribulose <=> ADP + D-Ribulose 1-phosphate R12696 D-ribulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming); D-Ribulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde R12697 12,18-Didecarboxysiroheme <=> Dihydro-heme d1 R12698 Dihydro-heme d1 + Acceptor <=> Heme d1 + Reduced acceptor R12699 sn-Glycerol 1-phosphate + all-trans-Heptaprenyl diphosphate <=> Heptaprenylglyceryl phosphate + Diphosphate R12700 Heptaprenylglyceryl phosphate + H2O <=> Heptaprenylglycerol + Orthophosphate R12701 Heptaprenylglycerol + 2 Acetyl-CoA <=> Diacetylheptaprenylglycerol + 2 CoA R12702 Phosphatidylethanolamine + G13044 <=> 1,2-Diacyl-sn-glycerol + G13152 R12703 Allantoate + Orthophosphate <=> (S)-Ureidoglycine + Carbamoyl phosphate R12704 CMP-N-acetylneuraminate + Thomsen-Friedenreich antigen <=> CMP + G10794 R12705 UDP-N-acetyl-D-glucosamine + Thomsen-Friedenreich antigen <=> UDP + G13153 R12706 Nopaline + H2O + Acceptor <=> L-Arginine + 2-Oxoglutarate + Reduced acceptor R12707 Octopine + H2O + Acceptor <=> L-Arginine + Pyruvate + Reduced acceptor R12708 dihydroisopentenyldehydrorhodopin:acceptor 3,4-oxidoreductase; Dihydroisopentenyldehydrorhodopin + Acceptor <=> Isopentenyldehydrorhodopin + Reduced acceptor R12709 dihydrobisanhydrobacterioruberin:acceptor 3,4-oxidoreductase; Dihydrobisanhydrobacterioruberin + Acceptor <=> Bisanhydrobacterioruberin + Reduced acceptor R12710 bacterioruberin hydro-lyase (bisanhydrobacterioruberin-forming); Bacterioruberin <=> Bisanhydrobacterioruberin + 2 H2O R12711 Bacterioruberin <=> Monoanhydrobacterioruberin + H2O R12712 Monoanhydrobacterioruberin <=> Bisanhydrobacterioruberin + H2O R12713 1,6-anhydro-beta-D-glucopyranose:NAD+ 3-oxidoreductase; Levoglucosan + NAD+ <=> 3-Dehydrolevoglucosan + NADH + H+ R12714 ultra-long-chain fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating); Ultra-long-chain fatty acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Ultra-long-chain omega-hydroxy fatty acid + [Oxidized NADPH---hemoprotein reductase] + H2O R12715 decanoyl-[acyl-carrier protein],reduced ferredoxin:oxygen oxidoreductase (9,10-dehydrogenating); Decanoyl-[acp] + 4 Reduced ferredoxin + 2 Oxygen + 4 H+ <=> Dec-9-ynoyl-[acyl-carrier protein] + 4 Reduced ferredoxin + 4 H2O R12716 Decanoyl-[acp] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-enoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R12717 Dec-9-enoyl-[acyl-carrier protein] + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Dec-9-ynoyl-[acyl-carrier protein] + 2 Oxidized ferredoxin + 2 H2O R12718 S-methyl-5-thio-D-ribulose 1-phosphate 1,3-isomerase; S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-Methyl-1-thio-D-xylulose 5-phosphate R12719 S-methyl-5-thio-D-ribulose 1-phosphate 1,3-isomerase; S-Methyl-5-thio-D-ribulose 1-phosphate <=> S-Methyl-1-thio-D-ribulose 5-phosphate R12720 Coenzyme F420-0 + FMN <=> Dehydro coenzyme F420-0 + Reduced FMN R12721 ATP + Glycine <=> Diphosphate + Glycyl-AMP R12722 Glycyl-AMP + Peptidyl-carrier protein <=> AMP + Glycyl-[peptidyl-carrier protein] R12723 glycine:[glycyl-carrier protein] ligase (AMP-forming); ATP + Glycine + Peptidyl-carrier protein <=> AMP + Diphosphate + Glycyl-[peptidyl-carrier protein] R12724 C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine L-tyrosine-carboxylyase; C-Terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine + S-Adenosyl-L-methionine <=> C-Terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + CO2 + 5'-Deoxyadenosine + L-Methionine R12725 ATP + L-Alanine <=> Diphosphate + (L-Alanyl)adenylate R12726 (L-Alanyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Alanyl-[peptidyl-carrier protein] R12727 L-alanine:[L-alanyl-carrier protein] ligase (AMP-forming); ATP + L-Alanine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Alanyl-[peptidyl-carrier protein] R12728 ATP + L-Glutamate <=> Diphosphate + (L-Glutamyl)adenylate R12729 (L-Glutamyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Glutamyl-[peptidyl-carrier protein] R12730 L-glutamate:[L-glutamyl-carrier protein] ligase (AMP-forming); ATP + L-Glutamate + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Glutamyl-[peptidyl-carrier protein] R12731 6-deoxy-6-sulfo-D-fructose transaldolase; 6-Deoxy-6-sulfo-D-fructose + D-Glyceraldehyde 3-phosphate <=> (2S)-3-Sulfolactaldehyde + beta-D-Fructose 6-phosphate R12732 3-methylbutanoyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase; 3-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 5-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2 R12733 3-methylpropanoyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase; 2-Methylpropanoyl-CoA + Malonyl-[acyl-carrier protein] <=> 4-Methyl-3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2 R12734 (2S)-2-methylbutanoyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase; (S)-2-Methylbutanoyl-CoA + Malonyl-[acyl-carrier protein] <=> (4S)-4-Methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2 R12735 dodecanoyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase; Lauroyl-CoA + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CoA + CO2 R12736 hydroxycinnamoyl-CoA:5-hydroxyanthranilate N-hydroxycinnamoyltransferase; p-Coumaroyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide A + CoA R12737 hydroxycinnamoyl-CoA:5-hydroxyanthranilate N-hydroxycinnamoyltransferase; Caffeoyl-CoA + 5-Hydroxyanthranilate <=> Avenanthramide C + CoA R12738 acetyl-CoA:alpha-L-rhamnopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 2IV-O-acetyltransferase; Acetyl-CoA + G13154 <=> CoA + G13155 R12739 dTDP-beta-L-rhamnose:alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-rhamnosyltransferase (configuration-inverting); dTDP-L-rhamnose + alpha-D-Galactosyl-diphospho-ditrans,octacis-undecaprenol <=> dTDP + G13156 R12740 GDP-alpha-D-mannose:alpha-L-rhamnopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 4II-alpha-rhamnosyltransferase (configuration-retaining); GDP-D-mannose + G13156 <=> GDP + G13158 R12741 GDP-alpha-D-mannose:alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase (configuration-retaining); GDP-D-mannose + alpha-D-Galactosyl-diphospho-ditrans,octacis-undecaprenol <=> GDP + G13159 R12742 GDP-alpha-D-mannose:alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 2II-alpha-mannosyltransferase; GDP-D-mannose + G13159 <=> GDP + G13160 R12743 dTDP-beta-L-rhamnose:alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 2III-alpha-rhamnosyltransferase (configuration inverting); dTDP-L-rhamnose + G13160 <=> dTDP + G13154 R12744 CDP-alpha-D-abequose:2-O-acetyl-alpha-L-rhamnopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 3IV-alpha-abequosyltransferase (configuration retaining); CDP-abequose + G13155 <=> CDP + G13161 R12745 GDP-alpha-D-mannose:alpha-L-rhamnopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 4II-beta-mannosyltransferase (configuration inverting); GDP-D-mannose + G13156 <=> GDP + G13162 R12746 ATP:1,6-anhydro-beta-D-glucopyranose 6-phosphotransferase (hydrolyzing); ATP + Levoglucosan + H2O <=> ADP + D-Glucose 6-phosphate R12747 GTP:polyphosphate phosphotransferase; GTP + Polyphosphate <=> GDP + Polyphosphate R12748 (4-O-methyl)-D-glucuronate---lignin ester hydrolase; 4-O-Methyl-D-glucopyranuronate ester + H2O <=> 4-O-Methyl-D-glucuronic acid + Alcohol R12749 cyclic 2,3-diphosphoglycerate phosphohydrolyase; Cyclic 2,3-bisphospho-D-glycerate + H2O <=> 2,3-Bisphosphoglycerate R12750 C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one lyase (C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol-forming); C-Terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + 5'-Deoxyadenosine + L-Methionine + Acceptor <=> C-Terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + S-Adenosyl-L-methionine + Reduced acceptor R12751 S-Methyl-1-thio-D-xylulose 5-phosphate <=> Methanethiol R12752 1'-Hydroxy-gamma-carotene <=> 1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one R12753 S-adenosyl-L-methionine:1'-hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one O-methyltransferase; 1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one + S-Adenosyl-L-methionine <=> Thiothece-474 + S-Adenosyl-L-homocysteine R12754 CO2 + Hydrogen <=> Formate R12755 ATP:1,6-anhydro-N-acetyl-beta-muramate 6-phosphotransferase; ATP + 1,6-Anhydro-N-acetyl-beta-muramate + H2O <=> ADP + N-Acetylmuramic acid 6-phosphate R12756 Reduced FMN + Oxygen <=> FMN-N5-peroxide R12757 L-Serine <=> Ethanolamine + CO2 R12758 L-Tryptophan <=> Indole + Dehydroalanine R12759 L-Tyrosine <=> Phenol + Dehydroalanine R12760 UDP-N-acetyl-alpha-D-quinovosamine:NAD+ 4-dehydrogenase; UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + NADH + H+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-glucose + NAD+ R12761 L-lyxonate hydro-lyase; L-Lyxonate <=> 2-Dehydro-3-deoxy-L-arabinonate + H2O R12762 (2S)-2,3-dihydroxypropane-1-sulfonate hydro-lyase; (2S)-2,3-Dihydroxypropane-1-sulfonate <=> 3-Oxopropane-1-sulfonate + H2O R12763 isethionate sulfite-lyase; 2-Hydroxyethanesulfonate <=> Acetaldehyde + Sulfite R12764 (2S)-2,3-dihydroxypropane-1-sulfonate sulfite-lyase; (2S)-2,3-Dihydroxypropane-1-sulfonate <=> Hydroxyacetone + Sulfite R12765 ATP + L-Cysteine <=> Diphosphate + (L-Cysteinyl)adenylate R12766 (L-Cysteinyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Cysteinyl-protein R12767 L-cysteine:[L-cysteinyl-carrier protein] ligase (AMP-forming); ATP + L-Cysteine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Cysteinyl-protein R12768 aceneuramate pyruvate-lyase (N-acetyl-D-mannosamine-forming); Aceneuramate <=> N-Acetyl-D-mannosamine + Pyruvate R12769 N-Acetyl-alpha-neuraminate <=> Aceneuramate R12770 Aceneuramate <=> N-Acetyl-beta-neuraminate R12771 fatty acid:oxygen 2-oxidoreductase [(2R)-2-hydroperoxyfatty acid-forming]; Fatty acid + Oxygen <=> (2R)-2-Hydroperoxyfatty acid R12772 ATP + L-Threonine <=> Diphosphate + (L-Threonyl)adenylate R12773 (L-Threonyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Threonyl-[L-threonyl-carrier protein] R12774 L-threonine:[L-threonyl-carrier protein] ligase (AMP-forming); ATP + L-Threonine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Threonyl-[L-threonyl-carrier protein] R12775 (9Z,12Z,15Z)-Octadecatrienoic acid + Oxygen <=> 2(R)-HPOT R12776 (2,3-Dihydroxybenzoyl)adenylate + Aryl-carrier protein <=> AMP + 2,3-Dihydroxybenzoyl-[aryl-carrier protein] R12777 2,3-dihydroxybenzoate:[aryl-carrier protein] ligase (AMP-forming); ATP + 2,3-Dihydroxybenzoate + Aryl-carrier protein <=> AMP + Diphosphate + 2,3-Dihydroxybenzoyl-[aryl-carrier protein] R12778 primary alkyl sulfate ester,2-oxoglutarate:oxygen oxidoreductase (sulfate-hydrolyzing); Alkyl sulfate + 2-Oxoglutarate + Oxygen <=> Aldehyde + Succinate + CO2 + Sulfate R12779 ATP + L-Serine <=> Diphosphate + (L-Seryl)adenylate R12780 (L-Seryl)adenylate + Peptidyl-carrier protein <=> AMP + L-Seryl-[peptidyl-carrier protein] R12781 L-serine:[L-seryl-carrier protein] ligase (AMP-forming); ATP + L-Serine + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Seryl-[peptidyl-carrier protein] R12782 ATP + L-Tryptophan <=> Diphosphate + (L-Tryptophyl)adenylate R12783 (L-Tryptophyl)adenylate + Peptidyl-carrier protein <=> AMP + L-Tryptophyl-[peptidyl-carrier protein] R12784 L-tryptophan:[L-tryptophyl-carrier protein] ligase (AMP-forming); ATP + L-Tryptophan + Peptidyl-carrier protein <=> AMP + Diphosphate + L-Tryptophyl-[peptidyl-carrier protein] R12785 D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (arsenate-transferring); D-Glyceraldehyde 3-phosphate + Arsenate ion + NAD+ <=> 1-Arsono-3-phospho-D-glycerate + NADH R12786 dGMP:L-aspartate ligase (ADP-forming); ATP + dGMP + L-Aspartate <=> ADP + Orthophosphate + N6-Succino-2-amino-2'-deoxyadenylate R12787 glycine betaine:[Co(I) glycine betaine-specific corrinoid protein] Co-methyltransferase; Betaine + Co(I) corrinoid protein <=> N,N-Dimethylglycine + Methyl-Co(III) corrinoid protein R12788 S-adenosyl-L-methionine:[methyl coenzyme M reductase]-L-arginine C-5-(S)-methyltransferase; 2 S-Adenosyl-L-methionine + Protein-L-arginine + Reduced acceptor <=> S-Adenosyl-L-homocysteine + L-Methionine + 5'-Deoxyadenosine + Protein-(5S)-C-methyl-L-arginine + Acceptor R12789 3-amino-5-hydroxybenzoate:[acyl carrier protein] ligase (AMP-forming); ATP + 3-Amino-5-hydroxybenzoate + Acyl-carrier protein <=> 3-Amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + Diphosphate R12790 10-formyltetrahydrofolate:GDP-alpha-D-perosamine N-formyltransferase; 10-Formyltetrahydrofolate + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> Tetrahydrofolate + GDP-N-formyl-alpha-D-perosamine R12791 poly(R)-3-hydroxyalkanoate (3R)-3-hydroxyacyltransferase; (3R)-3-Hydroxyacyl-CoA + Poly[(R)-3-hydroxyalkanoate]n(n) <=> CoA + Poly[(R)-3-hydroxyalkanoate]n(n+1) R12792 ATP:apulose 4-phosphotransferase; ATP + Apulose <=> ADP + Apulose 4-phosphate R12793 ATP:fatty acid 1-phosphotransferase; ATP + Fatty acid <=> ADP + Acyl phosphate R12794 3'-phosphoadenylyl-sulfate:omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase; 3'-Phosphoadenylyl sulfate + omega-Hydroxy-beta-dihydromenaquinone-9 <=> Adenosine 3',5'-bisphosphate + omega-Sulfo-beta-dihydromenaquinone-9 R12795 phospholipid sn-1 acylhydrolase; 1-Phosphatidyl-D-myo-inositol + H2O <=> 2-Acyl-sn-glycero-3-phospho-1D-myo-inositol + Fatty acid R12796 phospholipid sn-1 acylhydrolase; Phosphatidate + H2O <=> 2-Acyl-sn-glycerol 3-phosphate + Fatty acid R12797 primary alkyl sulfate ester sulfohydrolase; Alkyl sulfate + H2O <=> Alcohol + Sulfate R12798 branched primary-alkyl sulfate ester sulfohydrolase; 2-Butyloctyl sulfate + H2O <=> 2-Butyloctan-1-ol + Sulfate R12799 2-hydroxy-3-methyl fatty-CoA formyl-CoA lyase (2-methyl branched fatty aldehyde-forming); 2-Hydroxy-3-methyl-fatty-acyl-CoA <=> 2-Methyl-branched fatty aldehyde + Formyl-CoA R12800 (2R)-2-Hydroxy-long-chain fatty acyl-CoA <=> Long-chain fatty aldehyde + Formyl-CoA R12801 C-terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one hydrolyase; C-Terminal [mycofactocin precursor peptide]-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O <=> C-Terminal [mycofactocin precursor peptide]-glycine + 3-Amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one R12802 3-oxoisoapionate-4-phosphate transcarboxylase/glycolylhydrolase (3-phospho-D-glycerate-forming); 3-Oxoisoapionate 4-phosphate + H2O <=> Glycolate + 3-Phospho-D-glycerate R12803 (3R)-3-hydroxyacyl-[acyl-carrier protein]:UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine N-acyltransferase; (3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + Acyl-carrier protein R12804 (Salicyl)adenylate + Peptidyl-carrier protein <=> AMP + Salicyl-[peptidyl-carrier protein] R12805 salicylate:holo-[non-ribosomal peptide synthase] ligase; ATP + Salicylate + Peptidyl-carrier protein <=> AMP + Diphosphate + Salicyl-[peptidyl-carrier protein] R12806 CDP-glycerol:4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol glycerophosphotransferase; n CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-{Poly[(2R)-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12807 n UDP-glucose + 4-O-{Poly[(2R)-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-{Poly[(2R)-2-alpha-D-glucosyl-1-glycerophospho]-(2R)-glycerophospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12808 UDP-N-acetyl-D-glucosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> UDP + beta-GlcNAc-P-undecaprenol R12810 Phosphatidylglycerol + GalGlc-DAG <=> 1,2-Diacyl-sn-glycerol + GroP-Gal-Glc-DAG R12811 n beta-GlcNAc-P-undecaprenol + Polyglycerolphosphate lipoteichoic acid <=> n di-trans,poly-cis-Undecaprenyl phosphate + G13185 R12812 ATP + D-Alanine + G13185 <=> AMP + Diphosphate + G13186 R12813 n Phosphatidylglycerol + GroP-Gal-Glc-DAG <=> n 1,2-Diacyl-sn-glycerol + Polyglycerolphosphate lipoteichoic acid R12814 UDP-D-galactose + di-trans,poly-cis-Undecaprenyl phosphate <=> UDP + Und-P-Gal R12815 n Und-P-Gal + Polyglycerolphosphate lipoteichoic acid <=> n di-trans,poly-cis-Undecaprenyl phosphate + G13192 R12816 UDP-AATGal + di-trans,poly-cis-Undecaprenyl phosphate <=> G13195 + UMP R12817 UDP-D-glucose + G13195 <=> UDP + G13196 R12818 CDP-ribitol + G13196 <=> CMP + G13197 R12819 UDP-N-acetyl-D-galactosamine + G13197 <=> UDP + G13198 R12820 UDP-N-acetyl-D-galactosamine + G13198 <=> UDP + G13199 R12821 CDP-choline + G13199 <=> CMP + G13200 R12822 CDP-choline + G13200 <=> CMP + G13201 R12823 n G13201 <=> (n-1) di-trans,poly-cis-Undecaprenyl diphosphate + G13202 R12824 ATP:D-arabinose 1-phosphotransferase; ATP + D-Arabinose <=> ADP + alpha-D-Arabinopyranose 1-phosphate R12825 GTP:alpha-D-arabinopyranose-1-phosphate guanylyltransferase; GTP + alpha-D-Arabinopyranose 1-phosphate <=> Diphosphate + GDP-D-arabinopyranose R12826 3-epihydroxy-2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating); 3-Epihydroxy-2'-deoxymugineic acid + 2-Oxoglutarate + Oxygen <=> 3-Epihydroxymugineic acid + Succinate + CO2 R12827 Agroclavine + NADPH + H+ + Oxygen <=> Elymoclavine + NADP+ + H2O R12828 Elymoclavine + 2 NADPH + 2 H+ + 2 Oxygen <=> Paspalic acid + 2 NADP+ + 3 H2O R12829 Paspalic acid <=> Lysergic acid R12830 Lysergic acid <=> Ergotamine R12831 11-Oxocucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Carbonyl-20beta-hydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O R12832 11-Carbonyl-20beta-hydroxycucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Carbonyl-2beta,20beta-dihydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O R12833 Cucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O R12834 19-Hydroxycucurbitadienol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19,25-Dihydroxycucurbitadienol + [Oxidized NADPH---hemoprotein reductase] + H2O R12835 11-Carbonyl-2beta,20beta-dihydroxycucurbitadienol <=> Cucurbitacin D R12836 11-Carbonyl-2beta,20beta-dihydroxycucurbitadienol <=> Cucurbitacin I R12837 19,25-Dihydroxycucurbitadienol <=> Deacetylcucurbitacin C R12838 Coumarin + NADH + H+ <=> Dihydrocoumarin + NAD+ R12839 Osthenol <=> (+)-Columbianetin R12840 Cucurbitacin D + Acetyl-CoA <=> Cucurbitacin B + CoA R12841 Cucurbitacin I + Acetyl-CoA <=> Cucurbitacin E + CoA R12842 S-Adenosyl-L-methionine + Esculetin <=> S-Adenosyl-L-homocysteine + Isoscopoletin R12843 S-Adenosyl-L-methionine + Isoscopoletin <=> S-Adenosyl-L-homocysteine + Scoparone R12844 S-Adenosyl-L-methionine + Esculetin <=> S-Adenosyl-L-homocysteine + Scopoletin R12845 Deacetylcucurbitacin C + Acetyl-CoA <=> Cucurbitacin C + CoA R12846 Cholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R12847 22-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22,26-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O R12848 22,26-Dihydroxycholesterol + 2-Oxoglutarate + Oxygen <=> 16alpha,22,26-Trihydroxycholesterol + Succinate + CO2 R12849 Solanidine <=> Solanine R12850 Tomatidine <=> Tomatine R12851 adenylosuccinate lyase; N6-Succino-2-amino-2'-deoxyadenylate <=> dZMP + Fumarate R12852 guanylate kinase; dZMP + ATP <=> dZDP + ADP R12853 nucleoside-diphosphate kinase; dZDP + ATP <=> dZTP + ADP R12854 S-Adenosyl-L-methionine + 5-Hydroxybenzimidazole <=> S-Adenosyl-L-homocysteine + 5-Methoxybenzimidazole R12855 5-Methoxybenzimidazole <=> 5-Methoxy-6-methylbenzimidazole R12856 5-Methoxy-6-methylbenzimidazole <=> Dimethylbenzimidazole R12857 Cobamide coenzyme + H2O <=> Adenosyl cobinamide phosphate + alpha-Ribazole R12858 Xanthotoxin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-Hydroxyxanthotoxin + [Oxidized NADPH---hemoprotein reductase] + H2O R12859 UDP-N-acetyl-D-glucosamine + di-trans,poly-cis-Undecaprenyl phosphate <=> N-Acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UMP R12860 CDP-glycerol + N-Acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol R12861 n CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + PolyGroP-WTA R12862 n UDP-D-glucose + PolyGroP-WTA <=> n UDP + alpha-Glycosylated WTA R12863 ATP + D-Alanine + alpha-Glycosylated WTA <=> AMP + Diphosphate + G13180 R12864 CDP-ribitol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + Und-PP-GlcNAc-ManNAc-GroP-RboP R12865 n CDP-ribitol + Und-PP-GlcNAc-ManNAc-GroP-RboP <=> n CMP + PolyRboP-WTA R12866 n UDP-D-glucose + PolyRboP-WTA <=> n UDP + beta-Glycosylated WTA R12867 ATP + D-Alanine + beta-Glycosylated WTA <=> AMP + Diphosphate + G13171 R12868 CDP-glycerol + 4-O-[(2R)-1-Glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> CMP + G13172 R12869 n CDP-ribitol + G13172 <=> n CMP + G13173 R12870 n UDP-N-acetyl-D-glucosamine + G13173 <=> n UDP + alpha-O-GlcNAcylated WTA R12871 ATP + D-Alanine + alpha-O-GlcNAcylated WTA <=> AMP + Diphosphate + G13175 R12872 n UDP-N-acetyl-D-glucosamine + G13173 <=> n UDP + beta-O-GlcNAcylated WTA R12873 ATP + D-Alanine + beta-O-GlcNAcylated WTA <=> AMP + Diphosphate + G13177 R12874 n UDP-N-acetyl-D-glucosamine + G13173 <=> n UDP + G13178 R12875 ATP + D-Alanine + G13178 <=> AMP + Diphosphate + G13179 R12876 Bergamottin <=> Epoxybergamottin R12877 Xanthotoxin + NADPH + Oxygen + H+ <=> 5-Hydroxyxanthotoxin + NADP+ + H2O R12878 Scopoletin + NADPH + Oxygen + H+ <=> Fraxetin + NADP+ + H2O R12879 Esculetin + NADPH + Oxygen + H+ <=> 6,7,8-Trihydroxycoumarin + NADP+ + H2O R12880 Caffeoyl-CoA <=> Esculetin R12881 Bergaptol + Geranyl diphosphate <=> Bergamottin + Diphosphate R12882 Bergapten <=> Bergamottin R12883 Epoxybergamottin <=> 6',7'-Dihydroxybergamottin R12884 (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate <=> Paerucumarin R12885 3-Dehydroshikimate + NADP+ <=> 3,5-Dehydroshikimate + NADPH + H+ R12886 3,5-Dehydroshikimate <=> Gallate R12887 Xanthotoxol <=> 5,8-Dihydroxypsoralen R12888 Bergaptol <=> 5,8-Dihydroxypsoralen R12889 5,8-Dihydroxypsoralen <=> 8-Hydroxybergapten R12890 5,8-Dihydroxypsoralen <=> 5-Hydroxyxanthotoxin R12891 Bergapten <=> 8-Hydroxybergapten R12892 8-Hydroxybergapten <=> Isopimpinellin R12893 Psoralen <=> 5,8-Dihydroxypsoralen R12894 (R)-5-phosphomevalonate hydro-lyase; (R)-5-Phosphomevalonate <=> trans-Anhydromevalonate 5-phosphate + H2O R12895 trans-anhydromevalonate 5-phosphate carboxy-lyase; (2E)-3-methyl-5-phosphooxypent-2-enoate carboxy-lyase; trans-Anhydromevalonate 5-phosphate <=> Isopentenyl phosphate + CO2 R12896 prenyl diphosphate diphosphate phosphohydrolase; Dimethylallyl diphosphate + H2O <=> Dimethylallyl phosphate + Orthophosphate R12897 Prenol + ATP <=> Dimethylallyl phosphate + ADP R12898 UDP-D-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + beta-Glc-DAG R12899 UDP-D-glucose + beta-Glc-DAG <=> UDP + Glc2-DAG R12900 Phosphatidylglycerol + Glc2-DAG <=> 1,2-Diacyl-sn-glycerol + GroP-Glc2DAG R12901 n Phosphatidylglycerol + GroP-Glc2DAG <=> n 1,2-Diacyl-sn-glycerol + Polyglycerolphosphate lipoteichoic acid R12902 UDP-D-glucose + 1,2-Diacyl-sn-glycerol <=> UDP + alpha-Glc-DAG R12903 UDP-D-galactose + alpha-Glc-DAG <=> UDP + GalGlc-DAG R12904 ATP + D-Alanine + G13192 <=> AMP + Diphosphate + G13193 R12905 G13202 + alpha-Glc-DAG <=> G13203 + di-trans,poly-cis-Undecaprenyl diphosphate R12906 UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate <=> UDP-AATGal + 2-Oxoglutarate R12907 L-aspartate,NADPH:oxygen oxidoreductase [(2S)-2-nitrobutanedioate-forming]; L-Aspartate + 3 NADPH + 3 H+ + 3 Oxygen <=> (2S)-2-Nitrobutanedioate + 3 NADP+ + 4 H2O R12908 L-Aspartate + NADPH + H+ + Oxygen <=> N-Hydroxy-L-aspartate + NADP+ + H2O R12909 N-Hydroxy-L-aspartate + NADPH + H+ + Oxygen <=> N,N-Dihydroxy-L-aspartate + NADP+ + H2O R12910 N,N-Dihydroxy-L-aspartate <=> (2S)-2-Nitrosobutanedioate + H2O R12911 (2S)-2-Nitrosobutanedioate + NADPH + H+ + Oxygen <=> (2S)-2-Nitrobutanedioate + NADP+ + H2O R12912 3-amino-4-hydroxybenzoate,NADPH:oxygen oxidoreductase (2-hydroxylating); 3-Amino-4-hydroxybenzoate + NADPH + H+ + Oxygen <=> 3-Amino-2,4-dihydroxybenzoate + NADP+ + H2O R12913 (3S)-1,2-diazinane-3-carboxylate hydrolase (N5-hydroxy-L-ornithine-forming); N5-Hydroxy-L-ornithine <=> (3S)-1,2-Diazinane-3-carboxylate + H2O R12914 (E)-alk-1-en-1-SO-peroxol isomerase [(Z)-alkanethial S-oxide-forming]; (E)-Alk-1-en-1-SO-peroxol <=> (Z)-Alkanethial oxide R12915 malonyl-CoA:1-methylpyrrolinium malonyltransferase; 1-Methylpyrrolinium + 2 Malonyl-CoA + H2O <=> 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate + 2 CoA + 2 CO2 + H+ R12916 Phenyllactate + UDP-glucose <=> Phenyllactylglucose + UDP R12917 S-adenosyl-L-methionine:arsenous acid As-methyltransferase; S-Adenosyl-L-methionine + Arsenic triglutathione + Thioredoxin + 2 H2O <=> S-Adenosyl-L-homocysteine + Methanearsonous acid + 3 Glutathione + Thioredoxin disulfide R12918 S-adenosyl-L-methionine:arsenous acid As-methyltransferase; 2 S-Adenosyl-L-methionine + Arsenic triglutathione + 2 Thioredoxin + H2O <=> 2 S-Adenosyl-L-homocysteine + Dimethylarsinous acid + 3 Glutathione + 2 Thioredoxin disulfide R12919 S-adenosyl-L-methionine:arsenous acid As-methyltransferase; 3 S-Adenosyl-L-methionine + Arsenic triglutathione + 3 Thioredoxin <=> 3 S-Adenosyl-L-homocysteine + Trimethylarsane + 3 Glutathione + 3 Thioredoxin disulfide R12920 (3R)-3-hydroxyacyl-[acyl-carrier protein]:UDP-N-acetyl-alpha-D-glucosamine 3-O-(3-hydroxyacyl)transferase; (3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine <=> Acyl-carrier protein + UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine R12921 Nomega-methyl-L-arginine,NADH:oxygen oxidoreductase (Ndelta-hydroxy-Nomega-methyl-Nomega-nitroso-L-citrulline-forming); N(omega)-Methyl-L-arginine + 2 NADH + 2 H+ + 3 Oxygen <=> N(delta)-Hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + 2 NAD+ + 3 H2O R12922 N(omega)-Methyl-L-arginine + NADH + H+ + Oxygen <=> N(delta)-Hydroxy-N(omega)-methyl-L-arginine + NAD+ + H2O R12923 N(delta)-Hydroxy-N(omega)-methyl-L-arginine + NADH + H+ + Oxygen <=> N(delta),N'(omega)-Dihydroxy-N(omega)-methyl-L-arginine + NAD+ + H2O R12924 N(delta),N'(omega)-Dihydroxy-N(omega)-methyl-L-arginine + Oxygen <=> N(delta)-Hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + H2O R12925 copper(I):oxygen oxidoreductase; 4 Cu+ + 4 H+ + Oxygen <=> 4 Cu2+ + 2 H2O R12926 UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine amidohydrolase; UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O <=> UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + Acetate R12927 inulobiose hydro-lyase (alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride-forming); Inulobiose <=> alpha-D-Fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O R12928 S-adenosyl-L-methionine:3-amino-4-hydroxybenzoate 4-O-methyltransferase; S-Adenosyl-L-methionine + 3-Amino-2,4-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Amino-2-hydroxy-4-methoxybenzoate R12929 S-adenosyl-L-methionine:L-arginine Nomega-methyltransferase; S-Adenosyl-L-methionine + L-Arginine <=> S-Adenosyl-L-homocysteine + N(omega)-Methyl-L-arginine R12930 L-carnitine:[Co(I) quaternary-amine-specific corrinoid protein] Co-methyltransferase; L-Carnitine + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + L-Norcarnitine R12931 (3R)-3-hydroxyacyl-[acyl-carrier-protein]:UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose 3-N-[(3R)-hydroxyacyl]transferase; (3R)-3-Hydroxyacyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> Acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-{[(3R)-3-hydroxyacyl]amino}-alpha-D-glucopyranose R12932 acetyl-CoA:6-diazo-5-oxo-L-norleucine Nalpha-acetyltransferase; Acetyl-CoA + 6-Diazo-5-oxo-L-norleucine <=> CoA + N-Acetyl-6-diazo-5-oxo-L-norleucine R12933 7,8-Diaminononanoate + CO2 <=> 8-Amino-7-(carboxyamino)nonanoate R12934 8-Amino-7-(carboxyamino)nonanoate + ATP <=> Dethiobiotin + ADP + Orthophosphate R12935 8-amino-7-oxononanoate:[protein]-L-lysine aminotransferase (N-carboxylating); 8-Amino-7-oxononanoate + Protein lysine + CO2 <=> 8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate R12936 UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose:2-oxoglutarate aminotransferase; UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose + 2-Oxoglutarate <=> UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + L-Glutamate R12937 Chorismate + Ammonia <=> 2-Amino-2-deoxyisochorismate + H2O R12938 2-Amino-2-deoxyisochorismate + Ammonia <=> 4-Amino-4-deoxychorismate + Ammonia R12939 chorismate:L-glutamine aminotransferase (2-amino-4-deoxychorismate-forming); Chorismate + 2 L-Glutamine + H2O <=> 4-Amino-4-deoxychorismate + 2 L-Glutamate + Ammonia R12940 ATP:D-tagatopyranse-1-phosphate 6-phosphotransferase; ATP + D-Tagatopyranose 1-phosphate <=> ADP + D-Tagatose 1,6-bisphosphate R12941 glutathione-S-conjugate glycine hydrolase; R-S-Glutathione + H2O <=> [Gamma-glutamyl-L-cysteine]-S-conjugate + Glycine R12942 N-methyl carbamate ester hydrolase; N-Methyl carbamate ester + H2O <=> Alcohol + Methylamine + CO2 R12943 3-amino-2-hydroxy-4-methoxybenzoate:nitrite ligase (AMP-forming); ATP + 3-Amino-2-hydroxy-4-methoxybenzoate + Nitrite <=> AMP + Diphosphate + Cremeomycin + H2O R12944 UDP-N-acetyl-alpha-D-glucosamine:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide 6-beta-N-acetylglucosaminyltransferase (configuration-inverting); UDP-N-acetyl-alpha-D-glucosamine + G00399 <=> UDP + G00628 R12945 ATP:cob(II)alamin Cobeta-adenosyltransferase (diphosphate-forming); 2 ATP + 2 Cob(II)alamin + [Reduced NADPH---hemoprotein reductase] <=> 2 Diphosphate + 2 Orthophosphate + 2 Cobamide coenzyme + [Oxidized NADPH---hemoprotein reductase] R12946 S-methyl-1-thio-D-xylulose 5-phosphate:glutathione methylthiotransferase; S-Methyl-1-thio-D-xylulose 5-phosphate + Glutathione <=> 1-Deoxy-D-xylulose 5-phosphate + S-(Methylsulfanyl)glutathione R12947 2-nitrobutanedioate lyase (fumarate-forming); (2S)-2-Nitrobutanedioate <=> Fumarate + Nitrite R12948 (8S)-8-amino-7-oxononanoate:[protein]-L-lysine aminotransferase (N-carboxylating); (8S)-8-Amino-7-oxononanoate + Protein lysine + CO2 <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate R12949 (8S)-8-Amino-7-oxononanoate + Protein lysine + NADPH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NADP+ R12950 [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NADP+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADPH + H+ R12951 ATP:an alpha-Hep-(1->3)-alpha-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-[lipid A] heptoseI 4-O-phosphotransferase; ATP + G13205 <=> ADP + G13206 R12952 (8S)-8-Amino-7-oxononanoate + Protein lysine + NADH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NAD+ R12953 [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NAD+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADH + H+ R12954 Littorine <=> Hyoscyamine aldehyde R12955 uridine 5'-monophosphate phosphoribohydrolase; UMP + H2O <=> Uracil + D-Ribose 5-phosphate R12956 thymidine 5'-monophosphate phosphodeoxyribohydrolase; dTMP + H2O <=> Thymine + 2-Deoxy-D-ribose 1-phosphate R12957 L-Tryptophan <=> 3-(Aminomethyl)indole R12958 dIMP phosphohydrolase; 2'-Deoxyinosine 5'-phosphate + H2O <=> Deoxyinosine + Orthophosphate R12959 Hypotaurine + NADPH + H+ + Oxygen <=> Taurine + NADP+ + H2O R12960 3'-phosphoadenylyl-sulfate:lactosylceramide 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Lactosylceramide <=> Adenosine 3',5'-bisphosphate + Lactosylceramide sulfate R12961 lactosylceramide-sulfate sulfohydrolase; Lactosylceramide sulfate + H2O <=> Lactosylceramide + Sulfate R12962 UDP-N-acetyl-D-galactosamine:lactosylceramide-sulfate N-acetyl-D-galactrosaminyltransferase; UDP-N-acetyl-D-galactosamine + Lactosylceramide sulfate <=> UDP + Gangliotriaosylceramide-II3 sulfate R12963 gangliotriaosylceramide-II3-sulfate N-acetylgalactosaminohydrolase; Gangliotriaosylceramide-II3 sulfate + H2O <=> Lactosylceramide sulfate + N-Acetyl-D-galactosamine R12964 (2R)-2-hydroxy-4-(methylsulfanyl)butanoate:NAD+ 2-oxidoreductase; (2R)-2-Hydroxy-4-(methylsulfanyl)butanoate + NAD+ <=> 4-Methylthio-2-oxobutanoic acid + NADH + H+ R12965 6-deoxoteasterone,[reduced NADPH-hemoprotein reductase]:oxygen 3-oxidoreductase; 6-Deoxoteasterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3-Dehydro-6-deoxoteasterone + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R12966 benzylmalonyl-CoA:oxygen oxidoreductase (decarboxylating); Benzylmalonyl-CoA + Oxygen <=> (E)-Cinnamoyl-CoA + CO2 + Hydrogen peroxide R12967 sarcosine,5,6,7,8-tetrahydrofolate:O2 oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming); Sarcosine + Tetrahydrofolate + Oxygen <=> Glycine + 5,10-Methylenetetrahydrofolate + Hydrogen peroxide R12968 (indol-3-yl)acetate:CoA ligase (AMP-forming); ATP + Indole-3-acetate + CoA <=> AMP + Diphosphate + S-2-(Indol-3-yl)acetyl-CoA R12969 beta-D-glucosyl-N-acylsphingosine glycohydrolase (configuration-retaining); Glucosylceramide + H2O <=> N-Acylsphingosine + beta-D-Glucose R12970 beta-D-galactosyl-N-acylsphingosine glycohydrolase (configuration-retaining); Galactosylceramide + H2O <=> N-Acylsphingosine + beta-D-Galactose R12971 alpha-L-arabinopyranose:NAD+ 1-oxidoreductase; alpha-L-Arabinopyranose + NAD+ <=> L-Arabinono-1,4-lactone + NADH + H+ R12972 alpha-L-arabinopyranose:NADP+ 1-oxidoreductase; alpha-L-Arabinopyranose + NADP+ <=> L-Arabinono-1,4-lactone + NADPH + H+ R12973 N-Acetyl-D-glucosamine + Oxygen <=> N-Acetyl-D-glucosamino-1,5-lactone + Hydrogen peroxide R12974 N-Acetyl-D-glucosamino-1,5-lactone + H2O <=> N-Acetyl-D-glucosaminate R12975 N-acetyl-D-galactosamine:oxygen 1-oxidoreductase; N-Acetyl-D-galactosamine + Oxygen + H2O <=> N-acetyl-D-galactosaminate + Hydrogen peroxide R12976 N-Acetyl-D-galactosamine + Oxygen <=> N-Acetyl-D-galactosamino-1,5-lactone + Hydrogen peroxide R12977 N-Acetyl-D-galactosamino-1,5-lactone + H2O <=> N-acetyl-D-galactosaminate R12978 acetyl-CoA:N-terminal-Met-[tubulin] Met-Nalpha-acetyltransferase; Acetyl-CoA + N-Terminal-L-methionyl-[tubulin] <=> N-Terminal-Nalpha-acetyl-L-methionyl-[tubulin] + CoA R12979 beta-D-glucosyl-(1->4)-D-galactose:phosphate alpha-D-glucosyltransferase (configuration-inverting); beta-D-Glucosyl-(1->4)-D-galactose + Orthophosphate <=> D-Glucose 1-phosphate + D-Galactose R12980 ATP:NAD+ 3'-phosphotransferase; ATP + NAD+ <=> ADP + 3'-NADP+ R12981 succinyl-CoA:2-phenylsuccinate CoA-transferase; Phenylsuccinate + Succinyl-CoA <=> 2-Phenylsuccinyl-CoA + Succinate R12982 succinyl-CoA:3-phenylsuccinate CoA-transferase; Phenylsuccinate + Succinyl-CoA <=> 3-Phenylsuccinyl-CoA + Succinate R12983 kojibiose glucohydrolase (configuration-inverting); 2-alpha-D-Glucosyl-D-glucose + H2O <=> beta-D-Glucose + D-Glucose R12984 alpha-isomaltosyl-(1->3)-1,4-alpha-D-glucan:1,4-alpha-D-glucan 3-alpha-isomaltosyltransferase; 2 alpha-Isomaltosyl-(1->4)-maltotriose <=> alpha-Isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose + Maltotriose R12985 alpha-isomaltosyl-(1->3)-1,4-alpha-D-glucan:1,4-alpha-D-glucan 3-alpha-isomaltosyltransferase; alpha-Isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose <=> Cyclobis-1,6-alpha-nigerosyl + Maltotriose R12986 alpha-D-xylopyranose aldose-ketose-isomerase; alpha-D-Xylose <=> alpha-D-Xylulofuranose R12987 adenine:NAD+ oxidoreductase; Adenine + NAD+ + H2O <=> 8-Hydroxyadenine + NADH + H+ R12988 8-hydroxyadenine:NAD+ oxidoreductase; 8-Hydroxyadenine + NAD+ + H2O <=> 2,8-Dihydroxyadenine + NADH + H+ R12989 adenine:oxygen oxidoreductase; Adenine + H2O + Oxygen <=> 8-Hydroxyadenine + Hydrogen peroxide R12990 8-hydroxyadenine:oxygen oxidoreductase; 8-Hydroxyadenine + H2O + Oxygen <=> 2,8-Dihydroxyadenine + Hydrogen peroxide R12991 beta-L-arabinopyranose aldose-ketose-isomerase; beta-L-Arabinopyranose <=> L-Ribulose R12992 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase; 8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + NADP+ <=> (9R,13R)-12-Oxo-phytodienoic acid + NADPH + H+ R12993 2 p-Coumaroylagmatine <=> Hordatine A R12994 2 Feruloylagmatine <=> Hordatine B R12995 UDP-glucose + Protopanaxatriol <=> UDP + Ginsenoside F1 R12996 6-deoxy-6-sulfo-D-glucopyranose isomerase (2-epimerizing); 6-sulfo-beta-D-quinovose isomerase (2-epimerizing); 6-Sulfo-beta-D-quinovose <=> 6-Sulfo-D-rhamnose R12997 D-glucose:NADP+ 6-oxidoreductase; D-Glucose + NADP+ <=> 6-Dehydro-D-glucose + NADPH + H+ R12998 UTP diphosphate-lyase (cyclizing; 3',5'-cyclic-UMP-forming); UTP <=> 3',5'-Cyclic UMP + Diphosphate R12999 [methylated methoxylated-aromatic-compound-specific corrinoid protein]:tetrahydromethanopterin methyltransferase; Methyl-Co(III) corrinoid protein + 5,6,7,8-Tetrahydromethanopterin <=> 5-Methyl-5,6,7,8-tetrahydromethanopterin + Co(I) corrinoid protein R13000 6-deoxy-6-sulfo-D-fructose:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; 6-Deoxy-6-sulfo-D-fructose + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + 4-Deoxy-4-sulfo-D-erythrose R13001 4-deoxy-4-sulfo-D-erythrulose:D-glyceraldehyde-3-phosphate glycolaldehydetransferase; 4-Deoxy-4-sulfo-D-erythrulose + D-Glyceraldehyde 3-phosphate <=> D-Xylulose 5-phosphate + Sulfoacetaldehyde R13002 solabiose:phosphate alpha-D-glucosyltransferase; Solabiose + Orthophosphate <=> D-Galactose + D-Glucose 1-phosphate R13003 ADP-L-glycero-beta-D-manno-heptose:an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[lipid A] 5-alpha-heptosyltransferase; ADP-L-glycero-beta-D-manno-heptose + G00651 <=> ADP + G06499 R13004 ADP-L-glycero-beta-D-manno-heptose:an alpha-L-glycero-D-manno-heptosyl-(1->5)-[alpha-Kdo-(2->4)]-alpha -Kdo-(2->6)-[lipid A] 3-alpha-heptosyltransferase; ADP-L-glycero-beta-D-manno-heptose + G06499 <=> ADP + G13207 R13005 ADP-L-glycero-beta-D-manno-heptose:an alpha-Hep-(1->3)-4-O-phospho-alpha-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-[lipid A] heptoseI 7-alpha-heptosyltransferase; ADP-L-glycero-beta-D-manno-heptose + G13208 <=> ADP + G13209 R13006 all-trans pentaprenyl diphosphate:sn-glycerol-1-phosphate pentaprenyltransferase; all-trans-Pentaprenyl diphosphate + sn-Glycerol 1-phosphate <=> sn-3-O-(Farnesylgeranyl)glycerol 1-phosphate + Diphosphate R13007 all-trans-pentaprenyl diphosphate:sn-3-O-(pentaprenyl)glycerol 1-phosphate pentaprenyltransferase; all-trans-Pentaprenyl diphosphate + sn-3-O-(Farnesylgeranyl)glycerol 1-phosphate <=> 2,3-Bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + Diphosphate R13008 4-deoxy-4-sulfo-D-erythrose ketose-aldose isomerase; 4-Deoxy-4-sulfo-D-erythrose <=> 4-Deoxy-4-sulfo-D-erythrulose R13009 isethionate:NAD+ oxidoreductase; 2-Hydroxyethanesulfonate + NAD+ <=> Sulfoacetaldehyde + NADH + H+ R13010 a D-glucoside:ferric c-type cytochrome 3-oxidoreductase; D-Glucoside + Ferricytochrome c <=> 3-Dehydro-D-glucoside + Ferrocytochrome c R13011 2-oxoadipate dioxygenase/carboxy lyase; 2-Oxoadipate + Oxygen <=> (R)-2-Hydroxyglutarate + CO2 R13012 (3R)-3-[(Carboxylmethyl)amino]fatty acid + 2-Oxoglutarate + Oxygen <=> (3R)-3-{[Carboxy(hydroxy)methyl]amino}fatty acid + Succinate + CO2 R13013 (3R)-3-{[Carboxy(hydroxy)methyl]amino}fatty acid + 2-Oxoglutarate + Oxygen <=> (3R)-3-Isocyanyl-fatty acid + Succinate + 2 CO2 + 2 H2O R13014 (3R)-3-[(carboxylmethyl)amino]fatty acid,2-oxoglutarate:oxygen oxidoreductase (isonitrile-forming); (3R)-3-[(Carboxylmethyl)amino]fatty acid + 2 2-Oxoglutarate + 2 Oxygen <=> (3R)-3-Isocyanyl-fatty acid + 2 Succinate + 3 CO2 + 2 H2O R13015 protein-L-histidine,2-oxoglutarate:oxygen oxidoreductase (3S-hydroxylating); Protein histidine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3S)-3-hydroxy-L-histidine + Succinate + CO2 R13016 glycine betaine,NADH:oxygen oxidoreductase (demethylating); Betaine + NADH + H+ + Oxygen <=> N,N-Dimethylglycine + NAD+ + Formaldehyde + H2O R13017 6-sulfo-D-quinovose,FMNH2:oxygen oxidoreductase; Sulfoquinovose + Reduced FMN + Oxygen <=> 6-Dehydro-D-glucose + FMN + Sulfite + H2O R13018 2alpha-hydroxytaxusin,[reduced NADPH---hemoprotein reductase]:oxygen 7-oxidoreductase; 2alpha-Hydroxytaxusin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2alpha,7beta-Dihydroxytaxusin + [Oxidized NADPH---hemoprotein reductase] + H2O R13019 taxusin,[reduced NADPH---hemoprotein reductase]:oxygen 2-oxidoreductase; Taxusin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2alpha-Hydroxytaxusin + [Oxidized NADPH---hemoprotein reductase] + H2O R13020 7beta-hydroxytaxusin,[reduced NADPH---hemoprotein reductase]:oxygen 2-oxidoreductase; 7beta-Hydroxytaxusin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2alpha,7beta-Dihydroxytaxusin + [Oxidized NADPH---hemoprotein reductase] + H2O R13021 secondary-alkyl amine:NAD+ oxidoreductase (deaminating); Secondary-alkyl amine + NAD+ + H2O <=> Ketone + NADH + Ammonia + H+ R13022 secondary-alkyl amine:NADP+ oxidoreductase (deaminating); Secondary-alkyl amine + NADP+ + H2O <=> Ketone + NADPH + Ammonia + H+ R13023 Iminoaspartate + H2O <=> Oxaloacetate + Ammonia R13024 N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen <=> 2-[(3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-oxohexylidene]amine + Hydrogen peroxide R13025 2-[(3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-oxohexylidene]amine + H2O <=> D-Glucosone + Amine R13026 N-(1-deoxy-D-fructos-1-yl)amine:oxygen 2-oxidoreductase (glucosone-forming); N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen + H2O <=> D-Glucosone + Amine + Hydrogen peroxide R13027 N-(1-deoxy-D-fructos-1-yl)amine:oxygen oxidoreductase (fructosamine-forming); N-(1-Deoxy-D-fructos-1-yl)amine + Oxygen + H2O <=> (1-Deoxy-D-fructos-1-yl)amine + Aldehyde + Hydrogen peroxide R13028 N,N-dimethylglycine:ferredoxin oxidoreductase (demethylating); N,N-Dimethylglycine + 2 Oxidized ferredoxin + H2O <=> Sarcosine + Formaldehyde + 2 Reduced ferredoxin + 2 H+ R13029 sarcosine:ferredoxin oxidoreductase (demethylating); Sarcosine + 2 Oxidized ferredoxin + H2O <=> Glycine + Formaldehyde + 2 Reduced ferredoxin + 2 H+ R13030 Sulfoacetate + CoA + ATP <=> Sulfoacetyl-CoA + AMP + Diphosphate R13031 L-Tyrosine + NADPH + Oxygen + H+ <=> 3,4-Dihydroxy-L-phenylalanine + NADP+ + H2O R13032 3,4-Dihydroxy-L-phenylalanine + NADPH + Oxygen + H+ <=> 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + NADP+ + 2 H2O R13033 carminate:oxygen 3'-oxidoreductase (H2O2-forming); Carminate + Oxygen <=> 3'-Dehydrocarminate + Hydrogen peroxide R13034 D-Lysine <=> 6-Amino-2-oxohexanoate R13035 Glutarate + Succinyl-CoA <=> Glutaryl-CoA + Succinate R13036 (R)-2-Hydroxyglutarate <=> 2-Oxoglutarate R13037 L-2-Aminoadipate 6-semialdehyde <=> L-2-Aminoadipate R13038 (3R)-3-[(carboxylmethyl)amino]fatty acid glycine-lyase ((2E)-unsaturated fatty acyl-[acyl-carrier protein]-forming); (3R)-3-[(Carboxylmethyl)amino]fatty acid + Acyl-carrier protein <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + Glycine + H2O R13039 Androstan-3alpha,17beta-diol + NAD+ <=> Androsterone + NADH + H+ R13040 5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+ R13041 11alpha-hydroxy-9,15-dioxoprostanoate:NAD+ Delta13-oxidoreductase; 11alpha-Hydroxy-9,15-dioxoprostanoate + NAD+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADH + H+ R13042 11alpha-hydroxy-9,15-dioxoprostanoate:NADP+ Delta13-oxidoreductase; 11alpha-Hydroxy-9,15-dioxoprostanoate + NADP+ <=> (13E)-11alpha-Hydroxy-9,15-dioxoprost-13-enoate + NADPH + H+ R13043 glutathione:12(S)-HPETE oxidoreductase; 2 Glutathione + 12(S)-HPETE <=> Glutathione disulfide + 12(S)-HETE + H2O R13044 12(R)-HPETE hydro-lyase; 12(R)-HPETE <=> 12-OxoETE + H2O R13045 12(S)-HPETE hydro-lyase; 12(S)-HPETE <=> 12-OxoETE + H2O R13046 poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl] amidohydrolase; Poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl] + H2O <=> Heparosan D-glucuronate + Acetate R13047 3'-phosphoadenylyl-sulfate:heparosan-D-glucuronate N-sulfonotransferase; 3'-Phosphoadenylyl sulfate + Heparosan D-glucuronate <=> Adenosine 3',5'-bisphosphate + Heparosan-N-sulfate D-glucuronate R13048 3'-phosphoadenylyl-sulfate:heparan-sulfate-containing-L-iduronate-2-sulfate 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Heparan sulfate containing L-iduronate 2-sulfate <=> Adenosine 3',5'-bisphosphate + 3-O-Sulfated heparan sulfate containing L-iduronate 2-sulfate R13049 (R)-lactate:NAD+,ferredoxin oxidoreductase; (R)-Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin R13050 (S)-lactate:NAD+,ferredoxin oxidoreductase; (S)-Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin R13051 daidzein 7-O-glucoside glucohydrolase; Daidzin + H2O <=> Daidzein + beta-D-Glucose R13052 genistein 7-O-beta-D-glucoside glucohydrolase; Genistin + H2O <=> Genistein + beta-D-Glucose R13053 Puerarin <=> Daidzein + 1,5-Anhydro-D-erythro-hex-1-en-3-ulose R13054 Daidzein + NADPH + H+ <=> (R)-Dihydrodaidzein + NADP+ R13055 (R)-Dihydrodaidzein <=> (S)-Dihydrodaidzein R13056 (S)-Dihydrodaidzein + NADPH + H+ <=> (3S,4R)-Tetrahydrodaidzein + NADP+ R13057 (3S,4R)-Tetrahydrodaidzein <=> Equol R13058 alpha-linolenoyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (6,7-cis-dehydrogenating); alpha-Linolenoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Stearidonoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O R13059 linoleoyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (6,7-cis-dehydrogenating); Linoleoyl-[glycerolipid] + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> gamma-Linolenoyl-[glycerolipid] + 2 Ferricytochrome b5 + 2 H2O R13060 (R)-Dihydrodaidzein <=> O-Desmethylangolensin R13061 Genistein <=> Dihydrogenistein R13062 Dihydrogenistein <=> 6'-Hydroxy-O-desmethylangolensin R13063 rutin rhamnohydrolase; Rutin + H2O <=> Isoquercitrin + beta-L-Rhamnose R13064 naringin rhamnohydrolase; Naringin + H2O <=> Naringenin 7-O-beta-D-glucoside + beta-L-Rhamnose R13065 quercetin 3-O-glucoside glucohydrolase; Isoquercitrin + H2O <=> Quercetin + beta-D-Glucose R13066 Apigenin <=> Naringenin R13067 Quercetin <=> Taxifolin R13068 Kaempferol <=> Dihydrokaempferol R13069 Luteolin <=> Eriodictyol R13070 Taxifolin + NADH + H+ <=> 2-Hydroxy-1-(2,4,6-trihydroxyphenyl)-3-(3,4-dihydroxyphenyl)propan-1-one + NAD+ R13071 Dihydrokaempferol + NADH + H+ <=> 2-Hydroxy-1-(2,4,6-trihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one + NAD+ R13072 Eriodictyol + NADH + H+ <=> 3-Hydroxyphloretin + NAD+ R13073 Naringenin + NADH + H+ <=> Phloretin + NAD+ R13074 Naringenin <=> 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one R13075 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one <=> (2E,4E)-2,4-Dihydroxy-4-[6-(4-hydroxyphenyl)-2,4-dioxodihydro-2H-pyran-3(4H)-ylidene]but-2-enoate R13076 (2E,4E)-2,4-Dihydroxy-4-[6-(4-hydroxyphenyl)-2,4-dioxodihydro-2H-pyran-3(4H)-ylidene]but-2-enoate + H2O <=> 5-(4-Hydroxyphenyl)-3-oxovalero-delta-lactone + Oxaloacetate R13077 5-(4-Hydroxyphenyl)-3-oxovalero-delta-lactone + H2O <=> 5-Hydroxy-5-(4-hydroxyphenyl)-3-oxopentanoate R13078 5-Hydroxy-5-(4-hydroxyphenyl)-3-oxopentanoate <=> 4-Hydroxy-4-(4-hydroxyphenyl)-butan-2-one + CO2 R13079 4-Hydroxy-4-(4-hydroxyphenyl)-butan-2-one <=> 4-Hydroxycinnamoylmethane + H2O R13080 double-stranded RNA adenine aminohydrolase; Adenine in double-stranded RNA + H2O <=> Hypoxanthine in double-stranded RNA + Ammonia R13081 naringenin 7-O-beta-D-glucoside glucohydrolase; Naringenin 7-O-beta-D-glucoside + H2O <=> Naringenin + beta-D-Glucose R13082 3-hydroxyphloretin acylhydrolase (phloroglucinol-forming); 3-Hydroxyphloretin + H2O <=> 3,4-Dihydroxyphenylpropanoate + Phloroglucinol R13083 Taxifolin <=> Alphitonin R13084 Dihydrokaempferol <=> Maesopsin R13085 Alphitonin + 2 H2O <=> 3,4-Dihydroxyphenylacetate + Phloroglucinol + CO2 + 2 H+ R13086 Maesopsin <=> 4-Hydroxyphenylacetate + Phloroglucinol R13087 UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose <=> UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-galactose R13088 UDP-N-acetyl-D-galactosaminuronic acid <=> UDP-2-acetamido-2-deoxy-L-altruronic acid R13089 alpha-D-ribose-1-phosphate 5-kinase (ATP); alpha-D-Ribose 1-phosphate + ATP <=> D-Ribose 1,5-bisphosphate + ADP R13090 D-ribulose-1,5-bisphosphate 5-phosphohydrolase; D-Ribulose 1,5-bisphosphate + H2O <=> D-Ribulose 1-phosphate + Orthophosphate R13091 (-)-5-Oxo-1,2-campholide <=> [(1R)-2,2,3-Trimethyl-5-oxocyclopent-3-enyl]acetate R13092 (-)-camphor,reduced putidaredoxin:oxygen oxidoreductase; (-)-Camphor + Reduced putidaredoxin + Oxygen <=> (-)-3-exo-Hydroxycamphor + Oxidized putidaredoxin + H2O R13093 3-exo-hydroxycamphor:NAD+ oxidoreductase; (-)-3-exo-Hydroxycamphor + NAD+ <=> (-)-Bornane-2,5-dione + NADH + H+ R13094 (+)-6-endo-Hydroxycamphor <=> Bornane-2,6-dione R13095 (+)-6-exo-Hydroxycamphor <=> Bornane-2,6-dione R13096 D-Glutamate + Acetyl-CoA <=> N-Acetyl-D-glutamate + CoA R13097 N-acetyl-glutamate racemase; N-Acetyl-D-glutamate <=> N-Acetyl-L-glutamate R13098 N-Acetyl-L-glutamate <=> L-Glutamate R13099 geranylgeranyl diphosphate-lyase [(-)-cyatha-3,12-diene-forming]; Geranylgeranyl diphosphate <=> (-)-Cyatha-3,12-diene + Diphosphate R13100 geranylgeranyl- diphosphate diphosphate-lyase (neoverrucosan-5beta-ol-forming); Geranylgeranyl diphosphate + H2O <=> Neoverrucosan-5beta-ol + Diphosphate R13101 geranylgeranyl-diphosphate diphosphate-lyase (verrucosan-2beta-ol-forming); Geranylgeranyl diphosphate + H2O <=> Verrucosan-2beta-ol + Diphosphate R13102 geranylgeranyl-diphosphate diphosphate-lyase [(R)-axinyssene-forming]; Geranylgeranyl diphosphate <=> (R)-Axinyssene + Diphosphate R13103 geranylgerany-diphosphate diphosphate-lyase (lydicene-forming); Geranylgeranyl diphosphate <=> Lydicene + Diphosphate R13104 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-exo-beta-bergamotene-forming]; trans,trans-Farnesyl diphosphate <=> (+)-exo-beta-Bergamotene + Diphosphate R13105 beta-L-fucopyranose:NADP+ 1-oxidoreductase; beta-L-Fucopyranose + NADP+ <=> L-Fucono-1,5-lactone + NADPH + H+ R13106 fumagillol:NADP+ 5-oxidoreductase; Fumagillol + NADP+ <=> 5-Dehydrofumagillol + NADPH + H+ R13107 S-adenosyl-L-methionine S-methyl-5'-thioadenosine-lyase (cyclizing; L-homoserine lactone-forming); S-Adenosyl-L-methionine <=> L-Homoserine lactone + 5'-Methylthioadenosine R13108 5-hydroxymethylcytosine in DNA,2-oxoglutarate:oxygen oxidoreductase; 5-Hydroxymethylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Formylcytosine in DNA + Succinate + CO2 + H2O R13109 5-formylcytosine in DNA,2-oxoglutarate:oxygen oxidoreductase; 5-Formylcytosine in DNA + 2-Oxoglutarate + Oxygen <=> 5-Carboxycytosine in DNA + Succinate + CO2 R13110 cyclopeptine,2-oxoglutarate:oxygen oxidoreductase; Cyclopeptine + 2-Oxoglutarate + Oxygen <=> Dehydrocyclopeptine + Succinate + CO2 + H2O R13111 dehydrocyclopeptine,2-oxoglutarate:oxygen oxidoreductase ((-)-cyclopenine-forming); Dehydrocyclopeptine + 2-Oxoglutarate + Oxygen <=> (-)-Cyclopenine + Succinate + CO2 R13112 Canavanine <=> Vinylglycine + N-Hydroxyguanidine R13113 Vinylglycine <=> (2E)-2-Aminobut-2-enoate R13114 (2E)-2-Aminobut-2-enoate + H2O <=> L-Homoserine R13115 L-canavanine N-hydroxyguanidine-lyase (L-homoserine-forming); Canavanine + H2O <=> L-Homoserine + N-Hydroxyguanidine R13116 L-Mimosine <=> 3-Hydroxy-4H-pyrid-4-one + Dehydroalanine R13117 (+)-exo-beta-bergamotene,[reduced NADPH---hemoprotein reductase] oxidoreductase (5-dehydro-6-demethoxyfumagillol-producing); (+)-exo-beta-Bergamotene + 2 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 5-Dehydro-6-demethoxyfumagillol + 2 [Oxidized NADPH---hemoprotein reductase] + 3 H2O R13118 (+)-exo-beta-Bergamotene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (5R)-Hydroxy-(+)-exo-beta-bergamotene + [Oxidized NADPH---hemoprotein reductase] + H2O R13119 (5R)-Hydroxy-(+)-exo-beta-bergamotene + Oxygen <=> (3S)-3-[2-Methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O R13120 (3S)-3-[2-Methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-Dehydro-6-demethoxyfumagillol + [Oxidized NADPH---hemoprotein reductase] + H2O R13121 thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming); N-(Sulfonatooxy)alkanimidothioate <=> Nitrile + Sulfate + Sulfur R13122 5-dehydro-6-demethoxyfumagillol,2-oxoglutarate:oxygen oxidoreductase (6-hydroxylating); 5-Dehydro-6-demethoxyfumagillol + 2-Oxoglutarate + Oxygen <=> 5-Dehydro-6-demethoxy-6-hydroxyfumagillol + Succinate + CO2 R13123 S-adenosyl-L-methionine:5-dehydro-6-demethoxy-6-hydroxyfumagillol 6-O-methyltransferase; S-Adenosyl-L-methionine + 5-Dehydro-6-demethoxy-6-hydroxyfumagillol <=> S-Adenosyl-L-homocysteine + 5-Dehydrofumagillol R13124 1,2-beta-D-glucan:D-glucoside 2-beta-D-glucosyltransferase (configuration-retaining); 1,2-beta-D-Glucan + D-Glucoside <=> 1,2-beta-D-Glucan + beta-D-Glucosyl-(1->2)-D-glucoside R13125 3-O-beta-D-glucopyranosyl-beta-D-glucuronide:phosphate alpha-D-glucosyltransferase; 3-O-beta-D-Glucosyl-beta-D-glucuronoside + Orthophosphate <=> beta-D-Glucuronoside + D-Glucose 1-phosphate R13126 palatinose alpha-1,6-glucohydrolase; Palatinose + H2O <=> alpha-D-Glucose + D-Fructose R13127 3-methylbut-3-en-1-yl diphosphate phosphohydrolase; Isopentenyl diphosphate + H2O <=> Isopentenyl phosphate + Orthophosphate R13128 3'-dehydrosucrose 3'-dehydroglucohydrolase; 3-Ketosucrose + H2O <=> 3-Dehydro-D-glucopyranose + D-Fructose R13129 N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming); N-(Sulfonatooxy)alkenimidothioic acid <=> Epithionitrile + Sulfate R13130 a 2,3-bis-O-phytanyl-sn-glycero-phospholipid:S-adenosyl-L-methionine,acceptor oxidoreductase (cyclyzing); 2 2,3-Bis-(O-phytanyl)-sn-glycero-phospholipid + 4 S-Adenosyl-L-methionine + 2 Reduced acceptor <=> Glycerol dibiphytanyl glycerol tetraether phospholipid + 4 L-Methionine + 4 5'-Deoxyadenosine + 2 Acceptor R13131 a 2,3-bis-O-phytanyl-sn-glycero-phospholipid:S-adenosyl-L-methionine,acceptor oxidoreductase (cyclyzing); 2,3-Bis-(O-phytanyl)-sn-glycero-phospholipid + 2 S-Adenosyl-L-methionine + Reduced acceptor <=> Macrocyclic archaeol phospholipid + 2 L-Methionine + 2 5'-Deoxyadenosine + Acceptor R13132 phenyl-N-(sulfonatooxy)methanimidothioate sulfate-lyase (benzylthiocyanate-forming); Phenyl-N-(sulfonatooxy)methanimidothioate <=> Benzyl thiocyanate + Sulfate R13133 N-(sulfonatooxy)prop-2-enimidothioate sulfate-lyase (prop2-enylthiocyanate-forming); N-(Sulfonatooxy)prop-2-enimidothioate <=> Prop-2-enylthiocyanate + Sulfate R13134 N-(sulfonatooxy)prop-2-enimidothioate sulfate-lyase; N-(Sulfonatooxy)prop-2-enimidothioate <=> 2-(Thiiran-2-yl)acetonitrile + Sulfate R13135 (-)-cyclopenine methyl-isocyanate lyase (viridicatin-forming); (-)-Cyclopenine <=> Viridicatin + Methyl isocyanate R13136 propanoate:NAD+ oxidoreductase; Propanoate + NAD+ <=> Acrylic acid + NADH + H+ R13137 succinate:ferricytochrome-c oxidoreductase; Succinate + 2 Ferricytochrome c <=> Fumarate + 2 Ferrocytochrome c R13138 sym-Homospermidine + Oxygen + H+ <=> N-(4-Aminobutylpyrrolinium) ion + Hydrogen peroxide + Ammonia R13139 N-(4-Aminobutylpyrrolinium) ion + Oxygen + H2O <=> N-(4-Oxobutylpyrrolinium) ion + Ammonia + Hydrogen peroxide R13140 N-(4-Oxobutylpyrrolinium) ion <=> 1-Formylpyrrolizidine + H+ R13141 homospermidine:oxygen oxidase (deaminating, cyclizing); sym-Homospermidine + 2 Oxygen + H2O <=> 1-Formylpyrrolizidine + 2 Hydrogen peroxide + 2 Ammonia R13142 2,6-Dichloro-p-benzoquinone + H2O <=> 2-Chloro-6-hydroxy-1,4-benzoquinone + Cl- R13143 2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2-Chloro-6-hydroxy-1,4-benzoquinone + 2 Cl- + FAD R13144 L-Fucose <=> beta-L-Fucopyranose R13145 Acetyl-CoA + 5 Malonyl-CoA + Acyl-carrier protein <=> Dodecapentaenoyl-[acyl-carrier protein] R13146 Fumagillol + Dodecapentaenoyl-[acyl-carrier protein] <=> Prefumagillin + Acyl-carrier protein R13147 Prefumagillin <=> Fumagillin R13148 L-Glutamate 5-semialdehyde + NADP+ + H2O <=> L-Glutamate + NADPH + H+ R13149 Oleanolic acid <=> Echinocystic acid R13150 Echinocystic acid <=> Quillaic acid R13151 Quillaic acid <=> Quillaic acid 3-O-beta-D-glucuronide R13152 Quillaic acid 3-O-beta-D-glucuronide + UDP-alpha-D-galactose <=> Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP R13153 Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP-D-xylose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide + UDP R13154 Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide + UDP-L-rhamnose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide + UDP R13155 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside R13156 Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside R13157 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside + UDP-L-rhamnose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13158 Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside + UDP-L-rhamnose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13159 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13160 Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13161 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13162 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-apiose <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13163 Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-apiose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13164 Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP-D-xylose <=> Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside + UDP R13165 Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside <=> Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide 28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-(beta-D-glucosyl-1,3)-alpha-L-rhamnosyl-1,2-(alpha-L-rhamnosyl-1,3)-4-O-acetyl-beta-D-fucoside R13166 2-Oxoadipate + Thiamin diphosphate <=> 4-Carboxy-1-hydroxybutyryl-ThPP + CO2 R13167 4-Carboxy-1-hydroxybutyryl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + Thiamin diphosphate R13168 3-oxo-5beta-steroid:NADP+ 4,5-oxidoreductase; 3-Oxo-5beta-steroid + NADP+ <=> 3-Oxo-Delta4-steroid + NADPH + H+ R13169 Sialyl-3-paragloboside + UDP-N-acetyl-D-galactosamine <=> IV4GalNAcb-SPG ganglioside + UDP R13171 UDP-GalNAc:Fuc alpha1->2Gal alpha1->3-N-acetylgalactosaminyltransferase; Globo-H + UDP-N-acetyl-D-galactosamine <=> Globo-A + UDP R13172 UDP-Gal:Fuc alpha1->2Gal alpha1->3-galactosyltransferase; Globo-H + UDP-D-galactose <=> Globo-B + UDP R13173 alpha-(1->3)-L-fucosyltransferase; Type II A antigen + GDP-L-fucose <=> III3,IV2Fuca,IV3GalNAca-nLc4-Cer + GDP R13174 alpha-(1->3)-L-fucosyltransferase; Type II B antigen + GDP-L-fucose <=> III3,IV2Fuca,IV3Gala-nLc4-Cer + GDP R13175 alpha-2,8-sialyltransferase; Monosialylgalactosylgloboside + CMP-N-acetylneuraminate <=> V3(NeuAc)2-Gb5Cer + CMP R13176 NADPH:NAD+ oxidoreductase (H+-transporting); NADPH + NAD+ + H+ <=> NADP+ + NADH + H+ R13177 acetyl-CoA:acetaldehyde acetyltransferase; (R)-Acetoin + CoA + NAD+ <=> Acetaldehyde + Acetyl-CoA + NADH + H+ R13178 D-glucosylsphingosine glucohydrolase; D-Glucosylsphingosine + H2O <=> D-Glucose + Sphingosine R13179 psychosine galactohydrolase; Psychosine + H2O <=> D-Galactose + Sphingosine R13180 S-adenosyl-L-methionine:gentamicin X2 C6'-methyltransferase; Gentamicin X2 + 2 S-Adenosyl-L-methionine + Reduced acceptor <=> Antibiotic G-418 + 5'-Deoxyadenosine + L-Methionine + S-Adenosyl-L-homocysteine + Acceptor R13181 2-dehydro-3-deoxy-L-fuconate (S)-lactaldehyde-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-L-fuconate <=> Pyruvate + (S)-Lactaldehyde R13182 S-Adenosyl-L-methionine + Cob(I)alamin <=> S-Adenosyl-L-homocysteine + Methylcobalamin R13183 Vitamin B12 + Reduced acceptor <=> Cob(I)alamin + Acceptor R13184 3'-dehydrocarminate lyase (kermesate-forming); 3'-Dehydrocarminate <=> 1,5-Anhydro-D-erythro-hex-1-en-3-ulose + Kermesate R13185 L-proline betaine:[Co(I) quaternary-amine-specific corrinoid protein] Co-methyltransferase; Stachydrine + Co(I) corrinoid protein <=> Methyl-Co(III) corrinoid protein + N-Methyl-L-proline R13186 [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine:NAD+ lipoyltranferase (NAD+-hydrolysing; 2''-O-lipoyl-ADP-D-ribose-forming); Enzyme N6-(lipoyl)lysine + NAD+ + H2O <=> [Lipoyl-carrier protein]-L-lysine + 2''-O-Lipoyl-ADP-D-ribose + Nicotinamide R13187 L-aspartyl-tRNAAsp:ergosterol-3beta-O-L-aspartyltransferase; L-Aspartyl-tRNA(Asp) + Ergosterol <=> tRNA(Asp) + Ergosteryl-3beta-O-L-aspartate R13188 ATP:[protein]-L-serine O-phosphotransferase; ATP + [Protein]-L-serine <=> ADP + [Protein]-O-phospho-L-serine R13189 ATP:[protein]-L-threonine O-phosphotransferase; ATP + [Protein]-L-threonine <=> ADP + [Protein]-O-phospho-L-threonine R13190 ergosteryl-3beta-O-L-aspartate aminoacylesterase; Ergosteryl-3beta-O-L-aspartate + H2O <=> Ergosterol + L-Aspartate R13191 ipecoside glucohydrolase; Ipecoside + H2O <=> Ipecoside aglycone + D-Glucose R13192 Deacetylipecoside <=> Ipecoside R13193 (1R)-(2-Amino-1-hydroxyethyl)phosphonate <=> (E)-2-Aminoethenylphosphonate + H2O R13194 (E)-2-Aminoethenylphosphonate + H2O <=> Phosphonoacetaldehyde + Ammonia R13195 (1R)-(2-amino-1-hydroxyethyl)phosphonate ammonia-lyase; (1R)-(2-Amino-1-hydroxyethyl)phosphonate <=> Phosphonoacetaldehyde + Ammonia R13196 4,5-unsaturated pyranuronate lyase (ring-opening); 4-Deoxy-L-threo-hex-4-enopyranuronate <=> 5-Dehydro-4-deoxy-D-glucuronate R13197 4,5-unsaturated pyranuronate lyase (ring-opening); 4-Deoxy-L-erythro-hex-4-enopyranuronate <=> (4S,5S)-4,5-Dihydroxy-2,6-dioxohexanoate R13198 Digalacturonate <=> 4-Deoxy-L-threo-hex-4-enopyranuronate + D-Galacturonate R13199 alpha-D-glucose-6-phosphate aldose-ketose-isomerase; alpha-D-Glucose 6-phosphate <=> D-Fructose 6-phosphate R13202 ATP:D-fructose-6-phosphate 2-phosphotransferase; ATP + D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 2,6-bisphosphate R13203 ATP:D-fructose-phosphate 6-phosphotransferase; ATP + D-Fructose 1-phosphate <=> ADP + D-Fructose 1,6-bisphosphate R13204 oxygenic photosynthesis; 6 CO2 + 6 H2O <=> alpha-D-Glucose + 6 Oxygen R13205 calvin cycle; 9 ATP + 6 NADPH + 3 CO2 + 5 H2O + 6 H+ <=> 9 ADP + 6 NADP+ + D-Glyceraldehyde 3-phosphate + 8 Orthophosphate R13206 reductive citrate cycle; 3 ATP + NADPH + 3 CO2 + HCO3- + NADH + 4 Reduced ferredoxin + Hydroquinone + 6 H+ <=> 3 ADP + NADP+ + Oxaloacetate + 3 Orthophosphate + NAD+ + 4 Oxidized ferredoxin + Quinone + H2O R13207 reductive citrate cycle; 3 ATP + NADPH + 4 CO2 + NADH + 4 Reduced ferredoxin + Hydroquinone + 6 H+ <=> 2 ADP + AMP + NADP+ + Oxaloacetate + 2 Orthophosphate + Diphosphate + NAD+ + 4 Oxidized ferredoxin + Quinone R13208 reductive acetyl-CoA pathway; ATP + 2 NADPH + 2 CO2 + CoA + NADH + 2 Reduced ferredoxin + 5 H+ <=> ADP + 2 NADP+ + Acetyl-CoA + Orthophosphate + NAD+ + 2 Oxidized ferredoxin + 2 H2O R13209 3-hydroxypropionate bi-cycle; 5 ATP + 6 NADPH + 3 HCO3- + Quinone + 6 H+ <=> 3 ADP + 2 AMP + 6 NADP+ + Pyruvate + 3 Orthophosphate + 2 Diphosphate + Hydroquinone + H2O R13210 dicarboxylate-hydroxybutyrate cycle; 3 ATP + 2 NADPH + 2 CO2 + CoA + 2 Reduced ferredoxin + Hydroquinone + H2O + 4 H+ <=> ADP + 2 AMP + 2 NADP+ + Acetyl-CoA + 3 Orthophosphate + Diphosphate + 2 Oxidized ferredoxin + Quinone R13211 hydroxypropionate-hydroxybutylate cycle; 4 ATP + 5 NADPH + 2 HCO3- + CoA + NAD+ + 4 H+ <=> 2 ADP + 2 AMP + 5 NADP+ + Acetyl-CoA + 2 Orthophosphate + 2 Diphosphate + NADH + H2O R13212 5alpha-pregnane-3,20-dione,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); 5alpha-Pregnane-3,20-dione + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5alpha-Pregnan-17alpha-ol-3,20-dione + [Oxidized NADPH---hemoprotein reductase] + H2O R13213 allopregnanolone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating); Allopregnanolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Oxidized NADPH---hemoprotein reductase] + H2O R13214 3-oxo-5alpha-steroid:NADP+ Delta4-oxidoreductase; 3-Oxo-5alpha-steroid + NADP+ <=> 3-Oxo-Delta4-steroid + NADPH + H+ R13215 5alpha-pregnan-17alpha-ol-3,20-dione:NADP+ Delta4-oxidoreductase; 5alpha-Pregnan-17alpha-ol-3,20-dione + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+ R13216 5alpha-pregnane-3alpha,17alpha-diol-20-one:NAD+ oxidoreductase; 5alpha-Pregnan-17alpha-ol-3,20-dione + NADH + H+ <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one + NAD+ R13217 5alpha-pregnane-3alpha,17alpha-diol-20-one:NADP+ 3-oxidoreductase; 5alpha-Pregnan-17alpha-ol-3,20-dione + NADPH + H+ <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one + NADP+ R13218 5alpha-pregnane-3alpha,17alpha-diol-20-one,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing); 5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Androsterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O R13219 androstan-3alpha,17beta-diol:NADP+ 17-oxidoreductase; Androsterone + NADPH + H+ <=> Androstan-3alpha,17beta-diol + NADP+ R13220 dihydrotestosterone:NADP+ 17-oxidoreductase; 5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+ R13221 dihydrotestosterone:NAD+ 17-oxidoreductase; 5alpha-Androstane-3,17-dione + NADH + H+ <=> Dihydrotestosterone + NAD+ R13222 3 ATP + NADPH + 3 CO2 + HCO3- + 2 NADH + 4 Reduced ferredoxin + 7 H+ <=> 3 ADP + NADP+ + Oxaloacetate + 3 Orthophosphate + 2 NAD+ + 4 Oxidized ferredoxin + H2O R13223 succinate:ubiquinone oxidoreductase; Ubiquinone + Succinate <=> Ubiquinol + Fumarate R13224 quinol:ferricytochrome-c oxidoreductase; Hydroquinone + 2 Ferricytochrome c <=> Quinone + 2 Ferrocytochrome c + 2 H+ R13225 4-carboxy-3-alkylbut-2-enoyl-[acyl-carrier protein] carboxy-lyase; 4-Carboxy-3-alkylbut-2-enoyl-[acyl-carrier protein] <=> 3-Alkylbut-2-enoyl-[acyl-carrier protein] + CO2 R13226 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-delta-cadinol-forming]; trans,trans-Farnesyl diphosphate + H2O <=> (+)-delta-Cadinol + Diphosphate R13227 hydrogen sulfide:[DsrC protein]-dithiol oxidoreductase (trisulfide-forming); Hydrogen sulfide + Protein dithiol + 2 p-Benzoquinone <=> Protein-trisulfide + 2 Hydroquinone R13228 pentaprenyl-diphosphate diphosphate-lyase [cyclizing, colleterpenol-forming]; all-trans-Hexaprenyl diphosphate + H2O <=> Colleterpenol + Diphosphate R13229 geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, dolasta-1(15),8-diene-forming]; Geranylgeranyl diphosphate <=> (5R,12R,14S)-Dolasta-1(15),8-diene + Diphosphate R13230 geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, delta-araneosene-forming]; Geranylgeranyl diphosphate <=> delta-Araneosene + Diphosphate R13231 geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, somaliensene A-forming); all-trans-Pentaprenyl diphosphate <=> Somaliensene A + Diphosphate R13232 geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-somaliensene B-forming); all-trans-Pentaprenyl diphosphate <=> (-)-Somaliensene B + Diphosphate R13233 2-epi-5-epi-valiolone:NAD+ 2,3-oxidoreductase; 2-epi-5-epi-Valiolone + NAD+ <=> Demethylgadusol + NADH + H+ R13234 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, variediene-forming); Geranylgeranyl diphosphate <=> Variediene + Diphosphate R13235 geranylfarneyl-diphosphate diphosphate-lyase (cyclizing, (2E)-alpha-cericerene-forming); all-trans-Pentaprenyl diphosphate <=> (2E)-alpha-Cericerene + Diphosphate R13236 S-adenosyl-L-methionine:demethylgadusol 2-O-methyltransferase; S-Adenosyl-L-methionine + Demethylgadusol <=> S-Adenosyl-L-homocysteine + Gadusol R13237 acetyl-[acp]:3-oxoacyl-[acp] C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); Acetyl-[acyl-carrier protein] + 3-Oxoacyl-[acyl-carrier protein] <=> 3-Carboxymethyl-3-hydroxy-acyl-[acp] + Acyl-carrier protein R13238 carbendazim methanol hydrolase (decarboxylating); Carbendazim + H2O <=> 2-Aminobenzimidazole + CO2 + Methanol R13239 Carbendazim + H2O <=> N-(1H-1,3-Benzodiazol-2-yl)carbamate + Methanol R13240 N-(1H-1,3-Benzodiazol-2-yl)carbamate <=> 2-Aminobenzimidazole + CO2 R13241 3-aminoavenalumate:nitrite ligase (AMP-forming); ATP + 3-Aminoavenalumate + Nitrite <=> AMP + Diphosphate + 3-Diazoavenalumate + H2O R13242 3-carboxymethyl-3-hydroxy-acyl-[acyl-carrier protein] hydro-lyase; 3-Carboxymethyl-3-hydroxy-acyl-[acp] <=> 4-Carboxy-3-alkylbut-2-enoyl-[acyl-carrier protein] + H2O R13243 myo-inositol-pentakisphosphate phosphohydrolase; D-myo-Inositol 1,2,4,5,6-pentakisphosphate + H2O <=> 1D-myo-Inositol 1,2,5,6-tetrakisphosphate + Orthophosphate R13244 myo-inositol-tetrakisphosphate phosphohydrolase; 1D-myo-Inositol 1,2,5,6-tetrakisphosphate + H2O <=> 1D-myo-Inositol 1,2,6-trisphosphate + Orthophosphate R13245 myo-inositol-trisphosphate phosphohydrolase; 1D-myo-Inositol 1,2,6-trisphosphate + H2O <=> 1D-myo-Inositol 1,2-bisphosphate + Orthophosphate R13246 myo-inositol-bisphosphate phosphohydrolase; 1D-myo-Inositol 1,2-bisphosphate + H2O <=> 1D-myo-Inositol 2-phosphate + Orthophosphate R13247 quinol:oxygen oxidoreductase (H+-transporting); 2 Hydroquinone + Oxygen + 8 H+ <=> 2 Quinone + 2 H2O + 8 H+ R13248 peptidoglycan N-acetylmuramate---N-acetyl-beta-D-glucosamine lyase; G13347 <=> G13345 + G13346 R13249 L-Serine <=> Aminomalonyl-[acp] R13250 Fe(II):oxygen oxidoreductase ([FeO(OH)]core-producing); 4 Fe2+ + Oxygen + 6 H2O <=> 4 Iron(III) oxide-hydroxide + 8 H+ R13251 2 Fe2+ + Oxygen + 4 H2O <=> 2 Iron(III) oxide-hydroxide + 4 H+ + Hydrogen peroxide R13252 2 Fe2+ + Hydrogen peroxide + 2 H2O <=> 2 Iron(III) oxide-hydroxide + 4 H+ R13253 deacetylipecoside glucohydrolase; Deacetylipecoside + H2O <=> N-Deacetylipecoside aglycone + D-Glucose R13254 6-O-methyl-N-deacetylipecoside glucohydrolase; 6-O-Methyl-N-deacetylipecoside + H2O <=> 6-O-Methyl-N-deacetylipecoside aglycone + D-Glucose R13255 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, NADH, very-long-chain acyl-CoA forming); Acetyl-CoA + n Malonyl-CoA + n NADPH + n NADH + 2n H+ <=> Very-long-chain acyl-CoA + n CoA + n CO2 + n NADP+ + n NAD+ + n H2O R13256 very-long-chain acyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Very-long-chain acyl-CoA + HCO3- <=> ADP + Orthophosphate + Very-long-chain alpha-carboxyacyl-CoA R13257 long-chain-acyl-CoA:malonyl-[acyl-carrier protein] C-acyltransferase; Long-chain acyl-CoA + Malonyl-[acyl-carrier protein] <=> Long-chain 3-oxoacyl-[acyl-carrier protein] + CoA + CO2 R13258 long-chain-acyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating); Long-chain acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Long-chain 3-oxoacyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein R13259 long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase; Long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Long-chain 3-oxoacyl-[acyl-carrier protein] + NADPH + H+ R13260 long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (long-chain trans-2-enoyl-[acyl-carrier protein]-forming); Long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] <=> Long-chain trans-2-enoyl-[acyl-carrier protein] + H2O R13261 long-chain-acyl-[acyl-carrier protein]:NAD+ oxidoreductase; Long-chain acyl-[acyl-carrier protein] + NAD+ <=> Long-chain trans-2-enoyl-[acyl-carrier protein] + NADH + H+ R13262 very-long-chain-acyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating); Very-long-chain acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Very-long-chain 3-oxoacyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein R13263 very-long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase; Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Very-long-chain 3-oxoacyl-[acyl-carrier protein] + NADPH + H+ R13264 very-long-chain-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (very-long-chain trans-2-enoyl-[acyl-carrier protein]-forming); Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] <=> Very-long-chain trans-2-enoyl-[acyl-carrier protein] + H2O R13265 very-long-chain-acyl-[acyl-carrier protein]:NAD+ oxidoreductase; Very-long-chain acyl-[acyl-carrier protein] + NAD+ <=> Very-long-chain trans-2-enoyl-[acyl-carrier protein] + NADH + H+ R13266 ultra-long-chain-mono-unsaturated-acyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating); Ultra-long-chain mono-unsaturated acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Ultra-long-chain mono-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein R13267 ultra-long-chain-mono-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase; Ultra-long-chain mono-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain mono-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+ R13268 ultra-long-chain-mono-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (ultra-long-chain mono-unsaturated trans-2-enoyl-[acyl-carrier protein]-forming); Ultra-long-chain mono-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] <=> Ultra-long-chain mono-unsaturated trans-2-enoyl-[acyl-carrier protein] + H2O R13269 ultra-long-chain-mono-unsaturated-acyl-[acyl-carrier protein]:NAD+ oxidoreductase; Ultra-long-chain mono-unsaturated acyl-[acyl-carrier protein] + NAD+ <=> Ultra-long-chain mono-unsaturated trans-2-enoyl-[acyl-carrier protein] + NADH + H+ R13270 ultra-long-chain-di-unsaturated-acyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating); Ultra-long-chain di-unsaturated acyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Ultra-long-chain di-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + CO2 + Acyl-carrier protein R13271 ultra-long-chain-di-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase; Ultra-long-chain di-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain di-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+ R13272 ultra-long-chain-di-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (ultra-long-chain di-unsaturated trans-2-enoyl-[acyl-carrier protein]-forming); Ultra-long-chain di-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] <=> Ultra-long-chain di-unsaturated trans-2-enoyl-[acyl-carrier protein] + H2O R13273 ultra-long-chain-di-unsaturated-acyl-[acyl-carrier protein]:NAD+ oxidoreductase; Ultra-long-chain di-unsaturated acyl-[acyl-carrier protein] + NAD+ <=> Ultra-long-chain di-unsaturated trans-2-enoyl-[acyl-carrier protein] + NADH + H+ R13274 meromycolic-acid:holo-[acp Pks13] ligase; ATP + Meromycolic acid + Acyl-carrier protein <=> AMP + Diphosphate + Meromycoloyl-[acp Pks13] R13275 Meromycoloyl-[acp Pks13] + Very-long-chain alpha-carboxyacyl-CoA + alpha,alpha-Trehalose <=> Trehalose mycolic-beta-ketoester + CoA + CO2 + Acyl-carrier protein R13276 Trehalose monomycolate + NADP+ <=> Trehalose mycolic-beta-ketoester + NADPH + H+ R13277 trehalose monomycolate:trehalose monomycolate 6'-mycolyltransferase; 2 Trehalose monomycolate <=> alpha,alpha-Trehalose + Trehalose dimycolate R13278 trehalose monomycolate:AGP 5-mycolyltransferase; Trehalose monomycolate + AGP <=> alpha,alpha-Trehalose + mAGP R13279 Trehalose dimycolate + H2O <=> Mycolic acid + Trehalose monomycolate R13280 trehalose monomycolate:D-glucose 6-mycolyltransferase; Trehalose monomycolate + D-Glucose <=> alpha,alpha-Trehalose + Glucose monomycolate R13281 Hydrogen selenide + N-Acetyl-D-galactosamine <=> 1-Methylseleno-N-acetyl-D-galactosamine R13283 cis-4-hydroxycyclohexane-1-carboxylate:NAD+ 4-oxidoreductase; cis-4-Hydroxycyclohexane-1-carboxylate + NAD+ <=> 4-Oxocyclohexanecarboxylate + NADH + H+ R13284 N1-[(S)-3-amino-3-carboxypropyl]agmatine carboxy-lyase; N1-[(S)-3-amino-3-carboxypropyl]agmatine <=> N1-(3-Aminopropyl)agmatine + CO2 R13285 4-oxocyclohexane-1-carboxylate:oxygen oxidoreductase (4-oxocyclohex-2-ene-1-carboxylate-forming); 4-Oxocyclohexanecarboxylate + Oxygen <=> 4-Oxocyclohex-2-ene-1-carboxylate + Hydrogen peroxide R13286 putrescine,NADPH:oxygen oxidoreductase (N-hydroxylating); Putrescine + NADPH + H+ + Oxygen <=> N-Hydroxyputrescine + NADP+ + H2O R13287 4-Coumarate + H2O <=> 3-Hydroxy-3-(4-hydroxyphenyl)propanoate R13288 3-Hydroxy-3-(4-hydroxyphenyl)propanoate <=> 4-Hydroxybenzaldehyde + Acetate R13289 4-coumarate acetate-lyase (4-hydroxybenzaldehyde-forming); 4-Coumarate + H2O <=> 4-Hydroxybenzaldehyde + Acetate R13290 5,20-epoxytax-11-en-4alpha-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9alpha-hydroxylating); 5,20-Epoxytax-11-en-4alpha-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5,20-Epoxytax-11-ene-4alpha,9alpha-diol + [Oxidized NADPH---hemoprotein reductase] + H2O R13291 N1-[(S)-2-aminobutanoate]agmatine:NADP+ oxidoreductase (agmatine-forming); N1-[(S)-3-amino-3-carboxypropyl]agmatine + NADP+ + H2O <=> Agmatine + L-Aspartate 4-semialdehyde + NADPH + H+ R13292 pentaprenyl-diphosphate diphosphate-lyase [cyclizing, talaropentaene-forming]; all-trans-Hexaprenyl diphosphate <=> Talaropentaene + Diphosphate R13293 pentaprenyl-diphosphate diphosphate-lyase [cyclizing, macrophomene-forming]; all-trans-Hexaprenyl diphosphate <=> Macrophomene + Diphosphate R13294 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, phomopsene-formimg); Geranylgeranyl diphosphate <=> Phomopsene + Diphosphate R13295 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, bonnadiene-formimg); Geranylgeranyl diphosphate <=> Bonnadiene + Diphosphate R13296 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, allokutznerene-formimg); Geranylgeranyl diphosphate <=> Allokutznerene + Diphosphate R13297 alpha-L-rhamnosyl-(1->4)-D-glucuronate lyase; alpha-L-Rhamnosyl-(1->4)-D-glucuronate <=> L-Rhamnose + 4-Deoxy-L-threo-hex-4-enopyranuronate R13298 acyl-CoA:phytol O-acyltransferase; Acyl-CoA + Phytol <=> Fatty acid phytyl ester + CoA R13299 succinyl-CoA---cyclohexane-1-carboxylate CoA-transferase; Succinyl-CoA + Cyclohexane-1-carboxylate <=> Succinate + Cyclohexane-1-carbonyl-CoA R13300 geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, cattleyene-formimg); Geranylgeranyl diphosphate <=> Cattleyene + Diphosphate R13301 acetyl-CoA:N-hydroxyputrescine N-acetyltransferase; Acetyl-CoA + N-Hydroxyputrescine <=> N1-Acetyl-N1-hydroxyputrescine + CoA R13302 prenyl-diphosphate:3-methylbut-3-en-1-yl-diphosphate transferase (adding 5 units of 3-methylbut-3-en-1-yl); Dimethylallyl diphosphate + 5 Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + 5 Diphosphate R13303 prenyl-diphosphate:hapalindole G prenyltransferase (ambiguine A-forming); Dimethylallyl diphosphate + Hapalindole G <=> Ambiguine A + Diphosphate R13304 prenyl-diphosphate:hapalindole U prenyltransferase (ambiguine H-forming); Dimethylallyl diphosphate + Hapalindole U <=> Ambiguine H + Diphosphate R13305 L-arginine:2-oxoglutarate aminotransferase; L-Arginine + 2-Oxoglutarate <=> 5-Guanidino-2-oxopentanoate + L-Glutamate R13306 L-aspartate:5-guanidino-3-methyl-2-oxopentanoate aminotransferase; L-Aspartate + (3R)-5-Guanidino-3-methyl-2-oxopentanoate <=> Oxaloacetate + (3R)-3-Methyl-L-arginine R13307 betaine-CoA hydrolase; Betaine-CoA + H2O <=> Betaine + CoA R13308 L-arginine aminodihydrolase (L-ornithine-forming); L-Arginine + 2 H2O <=> L-Ornithine + CO2 + 2 Ammonia R13309 (R)-salsolinol dopamine-hydrolase (acetaldehyde-forming); (R)-Salsolinol + H2O <=> Dopamine + Acetaldehyde R13310 (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-2-epi-prezizaene-forming); 2-cis,6-trans-Farnesyl diphosphate <=> (+)-2-epi-Prezizaene + Diphosphate R13311 (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-alpha-cedrene-forming); 2-cis,6-trans-Farnesyl diphosphate <=> (-)-alpha-Cedrene + Diphosphate R13312 geranyl diphosphate diphosphate lyase [(Z)-beta-ocimene-forming]; Geranyl diphosphate <=> (Z)-beta-Ocimene + Diphosphate R13313 ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-beyerene-forming); ent-Copalyl diphosphate <=> ent-Beyerene + Diphosphate R13314 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole cyclase (hapalindole U-forming); 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> Hapalindole U R13315 ATP + 2 N1-Hydroxy-N1-succinylputrescine <=> AMP + Diphosphate + Pre-putrebactin R13316 ATP + Pre-putrebactin <=> AMP + Diphosphate + Putrebactin R13317 N1-hydroxy-N1-succinylputrescine:N1-hydroxy-N1-succinylputrescine ligase; 2 ATP + 2 N1-Hydroxy-N1-succinylputrescine <=> 2 AMP + 2 Diphosphate + Putrebactin R13318 ATP + 2 N1-Hydroxy-N1-succinylcadaverine <=> AMP + Diphosphate + Bisucaberin B R13319 ATP + Bisucaberin B <=> AMP + Diphosphate + Bisucaberin R13320 N1-hydroxy-N1-succinylcadaverine:N1-hydroxy-N1-succinylcadaverine ligase; 2 ATP + 2 N1-Hydroxy-N1-succinylcadaverine <=> 2 AMP + 2 Diphosphate + Bisucaberin R13321 (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoate lyase; (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid <=> (9Z,11E)-12-[(1E)-Hex-1-en-1-yloxy]dodeca-9,11-dienoic acid + H2O R13322 Ferulate + H2O <=> 3-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate R13323 3-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetate R13324 ferulate acetate-lyase (vanillin-forming); Ferulate + H2O <=> 4-Hydroxy-3-methoxy-benzaldehyde + Acetate R13325 4-Oxocyclohex-2-ene-1-carboxylate <=> 4-Oxocyclohex-2,5-dienecarboxylate R13326 4-Oxocyclohex-2,5-dienecarboxylate <=> 4-Hydroxybenzoate R13327 cyclohexane-1-carboxylate,ferredoxin:oxygen oxidoreductase (4-trans-hydroxylating); Cyclohexane-1-carboxylate + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> trans-4-Hydroxycyclohexanecarboxylate + 2 Oxidized ferredoxin + H2O R13328 1D-myo-Inositol 3-phosphate + CDP-diacylglycerol <=> 1-Phosphatidyl-1D-myo-inositol 3-phosphate + CMP R13329 3,17-Didehydrostemmadenine <=> 17-Dehydropreakuammicine + H+ R13330 17-Dehydropreakuammicine + H2O <=> Norfluorocurarine + Methanol + CO2 R13331 17-Dehydropreakuammicine hydrate <=> Akuammicine + Formate R13332 Norfluorocurarine <=> 18-Hydroxynorfluorocurarine R13333 18-Hydroxynorfluorocurarine <=> Wieland-Gumlich aldehyde R13334 Wieland-Gumlich aldehyde <=> Prestrychnine R13335 Wieland-Gumlich aldehyde <=> Diaboline R13336 Prestrychnine <=> Strychnine + CO2 + H2O R13337 Prestrychnine <=> Isostrychnine + CO2 + H2O R13338 Strychnine <=> 10-Hydroxystrychnine R13339 10-Hydroxystrychnine <=> beta-Colubrine R13340 beta-Colubrine <=> 11-Demethylbrucine R13341 11-Demethylbrucine <=> Brucine R13342 (19E)-Geissoschizine + Oxygen + [Reduced NADPH---hemoprotein reductase] + H+ <=> 3,17-Didehydrostemmadenine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R13343 acetyl-CoA:stemmadenine O-acetyltransferase; Stemmadenine + Acetyl-CoA <=> Stemmadenine acetate + CoA R13344 stemmadenine acetate:oxygen oxidoreductase; Stemmadenine acetate + Oxygen <=> Precondylocarpine acetate + Hydrogen peroxide R13345 precondylocarpine acetate:NADP+ oxidoreductase; Dihydroprecondylocarpine acetate + NADP+ <=> Precondylocarpine acetate + NADPH + H+ R13346 dehydrosecodine cyclase (tabersonine-forming); Dehydrosecodine <=> Tabersonine R13347 dehydrosecodine cyclase (catharanthine-forming); Dehydrosecodine <=> Catharanthine R13348 17-dehydrostemmadenine:NADP+ 3(4)-oxidoreductase; 17-Dehydrostemmadenine + NADP+ <=> 3,17-Didehydrostemmadenine + NADPH R13349 stemmadenine:NADP+ 17-oxidoreductase; Stemmadenine + NADP+ <=> 17-Dehydrostemmadenine + NADPH + H+ R13350 UDP-N-acetyl-alpha-D-glucosaminuronate carboxy-lyase; UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate <=> UDP-N-acetyl-alpha-D-xylosamine + CO2 R13351 1'-carboxy-chondrochloren carboxy-lyase; 1'-Carboxy-chondrochloren A + FAD <=> Chondrochloren A + CO2 + FADH2 R13352 1'-carboxy-chondrochloren carboxy-lyase; 1'-Carboxy-chondrochloren B + FAD <=> Chondrochloren B + CO2 + FADH2 R13353 2 ATP + 2 L-Glutamine + 2 FMN <=> 2 AMP + 2 Diphosphate + 2 3-Amino-1,5-dihydropyridine-2,6-dione + 2 Reduced FMN R13354 2 3-Amino-1,5-dihydropyridine-2,6-dione + Oxygen <=> Indigoidine + 2 H2O R13355 L-glutamine oxidoreductase/cyclase (3-amino-1,5-dihydropyridine-2,6-dione-forming); 2 ATP + 2 L-Glutamine + Oxygen + 2 FMN <=> 2 AMP + 2 Diphosphate + Indigoidine + 2 H2O + 2 Reduced FMN R13356 S-adenosyl-L-methionine:ajmaline N-methyltransferase; S-Adenosyl-L-methionine + Ajmaline <=> S-Adenosyl-L-homocysteine + 4-Methylajmaline R13357 S-adenosyl-L-methionine:(2R,3R,5S)-2-(S-pantetheinyl)-carbapenam-3-carboxylate 6-C-methyltransferase; (2R,3R,5S)-2-(S-Pantetheinyl)-carbapenam-3-carboxylate + 2 S-Adenosyl-L-methionine + Reduced acceptor <=> (2R,3R,5S,6R)-6-(Methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Acceptor R13358 S-adenosyl-L-methionine:(2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate 6-C-methyltransferase; (2R,3R,5S,6R)-6-(Methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 2 S-Adenosyl-L-methionine + Reduced acceptor <=> (2R,3R,5S,6R)-6-(Ethyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Acceptor R13359 3-dehydrocarnitine:acetyl-CoA trimethylamine transferase; 3-Dehydrocarnitine + Acetyl-CoA <=> Acetoacetate + Betaine-CoA R13360 3-oxoadipate:acetyl-CoA acetyltransferase; 3-Oxoadipate + Acetyl-CoA <=> Acetoacetate + Succinyl-CoA R13361 3,5-dioxohexanoate:acetyl-CoA acetone transferase; Triacetate + Acetyl-CoA <=> Acetoacetate + Acetoacetyl-CoA R13362 acetyl-CoA:rhazimol O-acetyltransferase; Acetyl-CoA + Rhazimol <=> CoA + Akuammiline R13363 O-phospho-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase; O-Phospho-L-homoserine + L-Cysteine <=> L-Cystathionine + Orthophosphate R13364 [(2S,3R,4R)-4-(6-aminopurin-9-yl)-3-(hydroxymethyl)oxetan-2-yl]methyl phosphate phosphohydrolase; 4'-Phosphooxetanocin A + H2O <=> Oxetanocin A + Orthophosphate R13365 [protein]-lanthionine hydrolase; [Protein]-L-serine + [Protein]-L-cysteine <=> [Protein] with lanthionine crosslink + H2O R13366 [Protein]-L-serine <=> [Protein]-dehydroalanine + H2O R13367 [Protein]-dehydroalanine + [Protein]-L-cysteine <=> [Protein] with lanthionine crosslink R13368 [protein]-(methyl)lanthionine hydrolase; [Protein]-L-threonine + [Protein]-L-cysteine <=> [Protein] with 3-methyllanthionine crosslink + H2O R13369 [Protein]-L-threonine <=> [Protein]-(Z)-2-aminobutenoate + H2O R13370 [Protein]-(Z)-2-aminobutenoate + [Protein]-L-cysteine <=> [Protein] with 3-methyllanthionine crosslink R13371 trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate phosphohydrolase; trans,octacis-Decaprenylphospho-beta-D-ribofuranose 5-phosphate + H2O <=> trans,octacis-Decaprenylphospho-beta-D-ribofuranose + Orthophosphate R13372 UDP-alpha-D-galactofuranose:beta-D-galactofuranoside beta-1,5-galactofuranosyltransferase (configuration-inverting); UDP-alpha-D-galactofuranose + beta-D-Galactofuranoside <=> UDP + beta-D-Galf-(1->5)-beta-D-galactofuranoside R13373 S-Adenosyl-L-methionine + Reduced acceptor <=> 5'-Deoxyadenosin-5'-yl radical + L-Methionine + Acceptor R13374 5'-Deoxyadenosin-5'-yl radical + dAMP + Acceptor <=> 4'-Phospho-dehydrooxetanocin + 5'-Deoxyadenosine + Reduced acceptor R13375 dAMP isomerase (4'-phospho-dehydrooxetanocin-forming); dAMP + S-Adenosyl-L-methionine <=> 4'-Phospho-dehydrooxetanocin + 5'-Deoxyadenosine + L-Methionine R13376 Dihydroprecondylocarpine acetate <=> Dehydrosecodine R13377 rhazimol:NADP+ oxidoreductase (rhazimol-forming); Rhazimol + NADP+ <=> Rhazimal + NADPH + H+ R13378 geissoschizine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (rhazimal forming); (19E)-Geissoschizine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Rhazimal + [Oxidized NADPH---hemoprotein reductase] + 2 H2O R13379 4-vinylguaiacol:oxygen oxidoreductase; 4-Vinylguaiacol + Oxygen <=> 4-Hydroxy-3-methoxy-benzaldehyde + Formaldehyde R13380 4-vinylphenol:oxygen oxidoreductase; 4-Hydroxystyrene + Oxygen <=> 4-Hydroxybenzaldehyde + Formaldehyde R13381 (19E)-geissoschizine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (akuammicine-forming); (19E)-Geissoschizine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Akuammicine + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O R13382 17-Dehydropreakuammicine + H2O <=> 17-Dehydropreakuammicine hydrate R13383 (20S)-19,20-dihydrovomilenine:NADP+ 19,20-oxidoreductase; (20S)-19,20-Dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+ R13384 2-(methylaminoethyl)phosphonate oxidase:oxygen oxidoreductase (phosphonoacetaldehyde-forming); N-Monomethyl-2-aminoethylphosphonate + Oxygen + H2O <=> Phosphonoacetaldehyde + Methylamine + Hydrogen peroxide R13385 Alkanesulfonate + H2O + 2 Oxidized ferredoxin <=> Aldehyde + Sulfite + 2 Reduced ferredoxin R13386 Aldehyde + H2O + Oxidized ferredoxin <=> Carboxylate + 2 Reduced ferredoxin + H+ R13387 aliphatic sulfonate:ferredoxin oxidoreductase (sulfite-releasing); Alkanesulfonate + 2 H2O + 4 Oxidized ferredoxin <=> Carboxylate + Sulfite + 4 Reduced ferredoxin + H+ R13388 quinone:selenite oxidoreductase; p-Benzoquinone + Selenite + H2O + 2 H+ <=> Hydroquinone + Selenate R13389 2-Aminoethylphosphonate oxidase:oxygen oxidoreductase (phosphonoacetaldehyde-forming); 2-Aminoethylphosphonate + Oxygen + H2O <=> Phosphonoacetaldehyde + Ammonia + Hydrogen peroxide R13390 UDP-N-acetyl-D-galactosamine + G13046 <=> UDP + G13350 R13391 UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase; UDP-D-galactose + G13350 <=> UDP + G13351 R13392 CMP-N-acetylneuraminate + G13351 <=> CMP + G13352 R13393 GDP-D-mannose + G13356 <=> GDP + G13357 R13394 C22963 + H2O <=> C22964 + Unsaturated fatty acid R13395 C22966 + H2O <=> C22967 + Unsaturated fatty acid R13396 C22964 + Stearoyl-CoA <=> C22965 + CoA R13397 C22967 + Cerotoyl-CoA <=> C22968 + CoA R13398 C22970 + H2O <=> C22971 + Hexadecanoic acid R13399 C22971 + H2O <=> C22963 + Ethanolamine phosphate R13400 Tetrathionate + H2O <=> Thiosulfate + Sulfur + Sulfate + H+