ENTRY K17830 KO SYMBOL GGR NAME digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] PATHWAY map00564 Glycerophospholipid metabolism map01110 Biosynthesis of secondary metabolites REACTION R10325 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NAD+ oxidoreductase R10326 2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate:NADP+ oxidoreductase R10331 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid:ferredoxin oxidoreductase BRITE KEGG Orthology (KO) [BR:ko00001] 09100 Metabolism 09103 Lipid metabolism 00564 Glycerophospholipid metabolism K17830 GGR; digeranylgeranylglycerophospholipid reductase Enzymes [BR:ko01000] 1. Oxidoreductases 1.3 Acting on the CH-CH group of donors 1.3.1 With NAD+ or NADP+ as acceptor 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] K17830 GGR; digeranylgeranylglycerophospholipid reductase 1.3.7 With an iron-sulfur protein as acceptor 1.3.7.11 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase GENES PMEX: H4W19_05940 PDD: MNQ95_14045 LAB: LA76x_2426 LAQ: GLA29479_2709 LGU: LG3211_2789 LEZ: GLE_2795 LEM: LEN_2236 LMB: C9I47_1426 LYT: DWG18_07380 LYJ: FKV23_07190 LSX: H8B22_00975 LHX: LYSHEL_30720 LCAS: LYSCAS_30690 THES: FHQ07_02060 TBV: H9L17_15740 THEX: ICG51_000228 HHC: M911_11185 EBS: ECTOBSL9_0276 TGR: Tgr7_2205 TKM: TK90_0643 TVR: TVD_10595 APRS: BI364_13760 SVA: SVA_2992 ACII: C4901_12925 ATY: A9R16_004045 CGD: CR3_0650(fixC) VPE: Varpa_3679 VBO: CKY39_19940 VAM: C4F17_03155 SDR: SCD_n00804 SULF: CAP31_01895 SPLB: SFPGR_29360 SNIV: SFSGTM_27200 URU: DSM104443_00527 BEBA: BWI17_02380 HDN: Hden_0684 RVA: Rvan_3542 FIL: BN1229_v1_0189 FIY: BN1229_v1_0193 CMAR: IMCC12053_1371 RHC: RGUI_1289 AMYL: QBD29_00465 AFR: AFE_2544 AFE: Lferr_2172 ACU: Atc_2341 ACZ: Acaty_c2184 AFI: Acife_2465 AFJ: AFERRID_05040 AFP: K1Y48_09080 DOL: Dole_0399 DTI: Desti_0238 DBR: Deba_3038 CBK: CLL_A1369 CLL_A1370 CLB: Clo1100_3094 Clo1100_3095 CLT: CM240_1758 CM240_1759 HSC: HVS_14075 CCE: Ccel_1057 Ccel_1058 RHER: EHE19_004620 EHE19_004625 RPAY: P0092_17605 SALQ: SYNTR_0780 DOR: Desor_4339 PTH: PTH_0378(FixC) DKU: Desku_2287 FWA: DCMF_14630 DGI: Desgi_1545 TEX: Teth514_0218 Teth514_0219 THX: Thet_0258 Thet_0259 TPD: Teth39_1995 TIT: Thit_0239 Thit_0240 TMT: Tmath_0322 Tmath_0323 TBO: Thebr_2044 TWI: Thewi_0279 TKI: TKV_c02330 TPZ: Tph_c09910(bchP) TXY: Thexy_2059 TSH: Tsac_0175 TEP: TepRe1_0379 TAE: TepiRe1_0421 BACG: D2962_14315 TOC: Toce_0251 NTH: Nther_1774 KME: H0A61_01699 STED: SPTER_30020(kmo) CALK: HUE98_00670 BALA: DSM104299_03518 PBAJ: LRS13_19280 PARN: NBH00_13915 PMT: PMT_0686 PMF: P9303_15361 PMJ: P9211_08531 CSN: Cyast_1222 MAR: MAE_31260 MPK: VL20_5387 MIQ: B5D77_03105 MVZ: myaer102_06730 CYC: PCC7424_4688 CYJ: Cyan7822_4141 PAGH: NIES204_25480 PPSU: NO713_00666 MVAG: D0A34_03765 OXY: HCG48_06915 OAC: Oscil6304_0659 ONI: Osc7112_3504 MIC: Mic7113_1946 GEI: GEI7407_1050 PLP: Ple7327_4278 ABAT: CFX1CAM_1448 KBS: EPA93_17655 KBB: ccbrp13_22200 PNL: PNK_0017 PND: Pla175_09780 FSU: Fisuc_0330 Fisuc_2122 FSC: FSU_0745 FSU_2657 POM: MED152_04120 POB: LPB03_12595 LPB03_16045 PRN: BW723_10930 POLA: BXQ17_11625 POA: CW731_11625 PLIT: K8354_10745 PBAT: JL193_08020 PCEA: J3359_02050 IAL: IALB_0329 HYA: HY04AAS1_0807 HHO: HydHO_0802 HYS: HydSN_0819 TAL: Thal_0865 TRD: THERU_04165 KPF: IX53_05590 CPO: COPRO5265_1158 CABY: Cabys_957 DTH: DICTH_0710 DTU: Dtur_0864 BANA: BARAN1_0630 BIH: BIP78_0559 MJA: MJ_0532 MFE: Mefer_0023 Mefer_0586 MVU: Metvu_0248 Metvu_0470 MFS: MFS40622_0302 MFS40622_0533 MIF: Metin_0313 MJH: JH146_0202 MESG: MLAUSG7_0668 MESA: MLASG1_0156 MIG: Metig_0018 MMP: MMP0388 MMQ: MmarC5_1250 MMX: MmarC6_0522 MMZ: MmarC7_1386 MMD: GYY_02010 MMAK: MMKA1_04070 MMAO: MMOS7_04030 MMAD: MMJJ_06490 MAE: Maeo_1307 MVN: Mevan_1375 MVO: Mvol_1689 MOK: Metok_0574 METF: CFE53_00320 MTH: MTH_1718 MTH_277 MMG: MTBMA_c02950 MTBMA_c07260 MTBMA_c11210 MWO: MWSIV6_0259 MWSIV6_0692 MWSIV6_1100 MTEE: MTTB_09190 MTTB_14720 METC: MTCT_0239 MTCT_1570 METE: tca_00257(menJ_1) tca_01663(menJ_2) METZ: METMT2_0572 METMT2_0721 METMT2_1561 METK: FVF72_00920 FVF72_03085 MTHM: FZP57_01175 FZP57_03320 FZP57_05215 METJ: FZP68_06180 FZP68_08325 MST: Msp_0758 Msp_0874 Msp_1062 Msp_1307 Msp_1320 METB: AW729_08940 AW729_09050 AW729_10575 AW729_10930 MEIS: PXD04_00860 PXD04_02310 PXD04_02685 MRU: mru_1341 mru_1441 mru_1471 MSI: Msm_1701 MEB: Abm4_0728 Abm4_1169 MMIL: sm9_1381 MEYE: TL18_04135 MOL: YLM1_0823 YLM1_0971 MARO: MarbSA_00110 METV: K4897_00040 MEL: Metbo_0471 Metbo_2033 Metbo_2366 MEW: MSWAN_0290 MSWAN_0605 MSWAN_1925 METH: MBMB1_0335 MBMB1_0639 MBMB1_1556 MBMB1_1827 MFC: BRM9_0792 BRM9_1599 BRM9_1933 BRM9_2158 MFI: DSM1535_0120 DSM1535_0754 DSM1535_1097 DSM1535_2293 MCUB: MCBB_0308 MCBB_0619 MCBB_1812 MSUB: BK009_01280 BK009_06770 BK009_11855 METN: BK008_02415 BK008_07495 BK008_09685 METT: CIT01_01350 CIT01_04015 CIT01_04025 CIT01_07320 CIT01_10150 METO: CIT02_03745 CIT02_05170 CIT02_08440 CIT02_10165 MEME: HYG87_07945 HYG87_10880 MFEG: GCM10025860_04480 GCM10025860_12360 GCM10025860_16550 MEER: NKF70_04595 NKF70_08080 NKF70_09965 MFV: Mfer_0516 Mfer_1222 MKA: MK1443 MK1645 AFU: AF_0464 AFG: AFULGI_00004710 APO: Arcpr_0713 AVE: Arcve_2050 AST: Asulf_00147 Asulf_01626 FPL: Ferp_0366 Ferp_1444 GAC: GACE_0072 GACE_0595 GAH: GAH_00300 GAH_00353 GAH_01689 PFU: PF0097 PFI: PFC_07720 PHO: PH0181(PH0181) PAB: PAB0109(bchP) PYN: PNA2_0702 PYA: PYCH_16330 PYS: Py04_0252 PYC: TQ32_00315 TKO: TK1088 TON: TON_0316 TGA: TGAM_1305 TSI: TSIB_0988 TBA: TERMP_00654 THE: GQS_03690 THA: TAM4_1982 THM: CL1_0388 TLT: OCC_08470 THS: TES1_0613 TNU: BD01_0182 TEU: TEU_06540 TGY: X802_10265 THV: ADU37_CDS08620 TCH: CHITON_0316 TPEP: A0127_09785 TPIE: A7C91_07555 TGG: A3K92_03945 TCE: A3L02_00260 TBS: A3L01_02245 THH: CDI07_02200 TSL: A3L11_06065 TTD: A3L14_03705 TPRF: A3L09_05905 TRL: A3L10_04285 TPAF: A3L08_04750 THY: A3L12_01970 TIC: FH039_04700 TCQ: TIRI35C_0673 THEM: FPV09_04700 THEI: K1720_08110 PPAC: PAP_07210 MBA: Mbar_A3422 MBY: MSBRM_1245 MSBRM_2785 MBW: MSBRW_1312 MBAR: MSBR2_1164 MSBR2_2742 MBAK: MSBR3_1297 MSBR3_2679 MAC: MA_1484 MA_2893 MA_3894 MA_4421 MMA: MM_0718 MM_2499 MM_3299 MMAZ: MmTuc01_0739 MmTuc01_2550 MmTuc01_3399 MMJ: MSMAS_0599 MSMAS_1387 MSMAS_2202 MMAC: MSMAC_0600 MSMAC_2252 MSMAC_2749 MVC: MSVAZ_0959 MSVAZ_1325 MSVAZ_1805 MEK: MSKOL_0928 MSKOL_1264 MSKOL_1782 MLS: MSLAZ_1440 MSLAZ_1542 MSLAZ_2928 METM: MSMTP_0646 MSMTP_0954 MSMTP_1509 MEF: MSWH1_1330 MSWH1_1478 MSWH1_1898 MEQ: MSWHS_1414 MSWHS_1853 MSWHS_3173 MSJ: MSSAC_1463 MSSAC_2883 MSSAC_4107 MSZ: MSSIH_1494 MSSIH_2538 MSSIH_3643 MSW: MSSIT_1552 MSSIT_2581 MSSIT_3698 MTHR: MSTHT_0217 MSTHT_0358 MSTHT_1727 MSTHT_2311 MTHE: MSTHC_0364 MSTHC_0514 MSTHC_0969 MSTHC_1561 MHOR: MSHOH_0251 MSHOH_1697 MSHOH_2811 MFZ: AOB57_000445 AOB57_001340 AOB57_003910 AOB57_007820 MBU: Mbur_0303 Mbur_0369 Mbur_0939 Mbur_1077 Mbur_1308 MMET: MCMEM_0833 MCMEM_0997 MCMEM_1441 MCMEM_1598 MCMEM_1755 MELO: J7W08_02385 J7W08_03355 J7W08_05920 J7W08_06945 J7W08_07805 MMH: Mmah_0579 Mmah_0675 Mmah_1258 Mmah_1613 MHAZ: BHR79_00515 BHR79_05660 BHR79_07245 BHR79_10225 MPOT: BKM01_01750 BKM01_07890 BKM01_09925 MEV: Metev_0262 Metev_0801 Metev_1607 Metev_1731 MZH: Mzhil_0235 Mzhil_0513 Mzhil_0683 Mzhil_1608 MPY: Mpsy_0099 Mpsy_1026 Mpsy_1467 Mpsy_2554 MZI: HWN40_01470 HWN40_03330 HWN40_05930 HWN40_09670 MMAV: RE476_00450 MSEB: RE474_10185 MHZ: Metho_0239 Metho_0947 Metho_1579 Metho_1933 MEHF: MmiHf6_00880(kmo) MEES: MmiEs2_09160(thi4_2) MmiEs2_09170(thi4_3) MTP: Mthe_0044 Mthe_0513 Mthe_0671 Mthe_0714 MCJ: MCON_1147 MCON_3250 MCON_3296 MHI: Mhar_0556 Mhar_1078 Mhar_1156 Mhar_2172 MHU: Mhun_1123 MRTJ: KHC33_08510 MLA: Mlab_0431 MEM: Memar_0506 Memar_1711 MBG: BN140_1582 MEMA: MMAB1_2023 MCHK: MchiMG62_06300 MSUM: OH143_09245 MRC: R6Y96_10195 MPI: Mpet_1752 MEND: L6E24_01525 MEFW: F1737_03510 MAQE: RJ40_04645 MFK: E2N92_04850 MOU: OU421_10180 MESB: L1S32_01385 MANQ: L1994_04690 MBN: Mboo_1945 MFO: Metfor_1011 MESK: METHP_00158 MPL: Mpal_0962 MPD: MCP_0504 MCP_1168 MCP_1480 MEZ: Mtc_0895(bchP) Mtc_1643 Mtc_1724 RCI: RCIX2051(bchP) RCIX2708 MJK: N2V74_06940 N2V74_07005 HAL: VNG_0468C HSL: OE_1699R HANR: LJ422_01955 HDL: HALDL1_06480 HHB: Hhub_1531 HAGS: JT689_03235 HABO: JRZ79_01735 HNO: LT974_03030 HLU: LT972_10470 HALH: HTSR_0966 HHSR: HSR6_0997 HSU: HLASF_0746 HSF: HLASA_0743 SALR: FQU85_11230 HALR: EFA46_006370 EFA46_006470 HJE: HacjB3_14420 HDO: MUK72_09380 HALX: M0R89_10965 HAXZ: M0R88_11400 HAYC: NGM10_04900 HAXY: NGM07_16955 SALI: L593_01650 SAIM: K0C01_10790 HARA: AArcS_1790(fixC3) HMA: rrnAC0726 HHI: HAH_1373 HHN: HISP_07025 HAB: SG26_14865 HTA: BVU17_06685 HALJ: G9465_08440 G9465_08805 G9465_20450 HSIN: KDQ40_06605 NPH: NP_4564A NMO: Nmlp_2334 Nmlp_3608 NHO: HWV23_05715 NSAL: HWV07_05475 HUT: Huta_0881 Huta_1007 Huta_2954 HTI: HTIA_0743 HTIA_2555 HALA: Hrd1104_04765 Hrd1104_09045 HMU: Hmuk_1955 Hmuk_2206 Hmuk_3091 Hmuk_3127 HALZ: E5139_02700 E5139_02875 E5139_12890 E5139_14170 HALL: LC1Hm_1280 LC1Hm_1619(fixC) LC1Hm_2428(fixC3) LC1Hm_2469(fixC4) HAZP: GBQ70_02700 GBQ70_12905 GBQ70_14185 HALI: BV210_03410 HSN: DV733_10365 HDS: HSR122_0270(fixC) HRR: HZS55_18830 HZS55_20705 HPEL: HZS54_21655 HZS54_22270 HZS54_24195 HLT: I7X12_15485 I7X12_16545 I7X12_17600 HARC: HARCEL1_04790 SSAI: N0B31_03370 HWA: HQ_1534A HWC: Hqrw_1635 Hqrw_3314 HVO: HVO_1799 HALE: G3A49_12170 HLN: SVXHx_2785(ggr) HME: HFX_1905(fixC) HGI: ABY42_08860 HLS: KU306_03510 HBO: Hbor_11300 HAQ: DU484_09565 DU484_17775 HAJ: DU500_00815 DU500_09815 HAER: DU502_06905 DU502_07185 DU502_16565 HRA: EI982_07520 EI982_14380 HLM: DV707_07230 HALM: FCF25_11425 HLA: Hlac_0926 HALP: DOS48_03545 HALB: EKH57_07685 HEZZ: EO776_04760 HALQ: Hrr1229_002660 HSS: J7656_12430 HSAI: HPS36_02425 HAZZ: KI388_02310 SRUB: C2R22_05450 HAE: halTADL_1048 HALN: B4589_000260 HALG: HUG10_08475 HALU: HUG12_17860 HDF: AArcSl_1381 AArcSl_1813 HAAA: AArcCO_0174(fixC) HAH: Halar_0855 HTU: Htur_1377 Htur_3081 HSAL: JMJ58_01855 JMJ58_05545 JMJ58_12995 JMJ58_22355 HAKZ: J0X25_02870 J0X25_13780 NMG: Nmag_0668 Nmag_1523 Nmag_2507 Nmag_2778 HXA: Halxa_3925 Halxa_3960 NAT: NJ7G_0898 NJ7G_2427 NPE: Natpe_0646 Natpe_1962 Natpe_3244 NVR: FEJ81_03545 NPL: FGF80_01135 FGF80_07435 NAY: HYG81_07440 HALY: HYG82_09140 HYG82_16990 HJT: DVR14_12450 HLO: J0X27_13130 NGE: Natgr_0786 Natgr_1266 Natgr_3103 HRU: Halru_1246 Halru_2474 SAWL: NGM29_01025 HALV: NGM15_10625 NOU: Natoc_0699 Natoc_2139 Natoc_4277 HLR: HALLA_08655 HALLA_13160 HALLA_17630 HLC: CHINAEXTREME15935 CHINAEXTREME19570 NAJ: B1756_02305 B1756_04290 B1756_12495 NAG: AArcMg_1023 AArcMg_2971 AArcMg_3119 NAN: AArc1_0731 AArc1_2601 AArc1_3025 NARA: QQ977_14385 NBG: DV706_00945 DV706_09380 DV706_16325 DV706_19090 NAS: GCU68_02695 GCU68_12755 HDA: BB347_05735 BB347_10350 BB347_10530 NAC: AQV86_03970 MELU: MTLP_05820 MTLP_05840 MTLP_09940 MEAM: MU439_04990 MEAE: QEN48_05175 TAC: Ta0516 TVO: TVG1046096(TVG1046096) TVG1579590(TVG1579590) OMR: OXIME_000276 PTO: PTO0568 PTO0896 FAC: FACI_IFERC01G0166 FAI: FAD_1079 CDIV: CPM_0295 CPM_0485 CPM_0894 TAR: TALC_00223 TALC_00435 TALC_00774 MAX: MMALV_02090 MMALV_03590 MMALV_08730 MER: MMINT_02130 MMINT_12590 MMINT_13170 MMINT_17750 MEAR: Mpt1_c01650 Mpt1_c12530 MEUZ: KRP56_01915 MARC: AR505_0892 AR505_1433 AR505_1618 ABI: Aboo_0578 ACF: AciM339_0374 AciM339_0468 SMR: Smar_1462 DKA: DKAM_0159 DFD: Desfe_0234 DMU: Desmu_0290 TAG: Tagg_0378 THG: TCELL_1246 HBU: Hbut_1257 STO: STK_04940 SOH: D1869_02295 SSO: SSO2353 SOL: Ssol_0166 SSOA: SULA_0158 SSOL: SULB_0159 SSOF: SULC_0158 SSHI: J5U23_01149 SCAS: SACC_19360 SIS: LS215_0182 SIA: M1425_0151 SIM: M1627_0151 SID: M164_0170 SIY: YG5714_0155 SIN: YN1551_2754 SII: LD85_0155 SIH: SiH_0155 SIR: SiRe_0151 SIC: SiL_0142 SULA: BFU36_10465 SULE: GFS03_02305 SULO: GFS33_08920 MSE: Msed_0681 MEMJ: MJ1HA_0791 MCN: Mcup_1399 MHK: DFR87_03150 MPRU: DFR88_03175 MTEN: GWK48_08960 MJN: MjAS7_1447 AHO: Ahos_2154 AMAN: B6F84_03335 ABRI: DFR85_06060 ASUL: DFR86_03340 AAMB: D1866_05750 ACIH: HS5_09650 SACD: HS1genome_0804 SAZO: D1868_10400 STEP: IC006_2737 SMET: RQ359_001719 CMA: Cmaq_0840 VDI: Vdis_1715 VMO: VMUT_2242 TPE: Tpen_0114 Tpen_0718 THB: N186_01490 N186_04950 TCB: TCARB_0050 TCARB_1382 THF: MA03_00905 MA03_06135 THEL: IG193_04155 IG193_06980 ACIA: SE86_02030 FFO: FFONT_1180 KCR: Kcr_0058 Kcr_1359 NMR: Nmar_0631 NIR: NSED_03245 NKR: NKOR_03230 NID: NPIRD3C_1636 NIN: NADRNF5_0722 NADRNF5_1519 NIW: Nisw_01750 NCL: C5F47_05915 NOX: C5F49_05755 C5F49_06640 NUE: C5F50_04660 NIP: NsoK4_05210 NZT: NZOSNM25_001364 NCT: NMSP_0453 NMSP_1055 NIC: DSQ20_03360 NGA: Ngar_c10460 Ngar_c11500 Ngar_c18750 NVN: NVIE_003360 NVIE_011700 NEV: NTE_01655 NTE_02579 TAA: NMY3_01977 NMY3_02141 NMY3_02989 NFN: NFRAN_0449 NFRAN_2927 NCV: NCAV_0324 NDV: NDEV_0107 NDEV_1206 CSY: CENSYa_0520 CENSYa_1317 CSU: CSUB_C1349 CSUB_C1610 NBV: T478_0510 T478_0975 TAH: SU86_000125 SU86_003010 NIU: DSQ19_03605 BARC: AOA65_1634 FLT: Sv326_0975 LOKI: Lokiarch_51240 LOB: NEF87_004200 PSYT: DSAG12_02297 AGW: QT03_C0001G0827 REFERENCE PMID:16788058 AUTHORS Nishimura Y, Eguchi T TITLE Biosynthesis of archaeal membrane lipids: digeranylgeranylglycerophospholipid reductase of the thermoacidophilic archaeon Thermoplasma acidophilum. JOURNAL J Biochem 139:1073-81 (2006) DOI:10.1093/jb/mvj118 SEQUENCE [tac:Ta0516] REFERENCE PMID:17288560 AUTHORS Murakami M, Shibuya K, Nakayama T, Nishino T, Yoshimura T, Hemmi H TITLE Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus. JOURNAL FEBS J 274:805-14 (2007) DOI:10.1111/j.1742-4658.2006.05625.x SEQUENCE [afu:AF_0464] ///