ENTRY K16792 KO SYMBOL aksD NAME methanogen homoaconitase large subunit [EC:4.2.1.114] PATHWAY map00300 Lysine biosynthesis map00680 Methane metabolism map01100 Metabolic pathways map01110 Biosynthesis of secondary metabolites map01120 Microbial metabolism in diverse environments map01210 2-Oxocarboxylic acid metabolism map01230 Biosynthesis of amino acids map01240 Biosynthesis of cofactors MODULE M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate REACTION R03444 (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase R04371 homoisocitrate hydro-lyase R09720 (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate-forming] R10391 (R)-(homo)2-citrate hydro-lyase [(-)-threo-iso(homo)2-citrate forming] R10392 (R)-(homo)2-citrate hydro-lyase R10393 (-)-threo-iso(homo)2-citrate hydro-lyase R10394 (R)-(homo)3-citrate hydro-lyase [(-)-threo-iso(homo)3-citrate forming] R10395 (R)-(homo)3-citrate hydro-lyase R10396 (-)-threo-iso(homo)3-citrate hydro-lyase BRITE KEGG Orthology (KO) [BR:ko00001] 09100 Metabolism 09102 Energy metabolism 00680 Methane metabolism K16792 aksD; methanogen homoaconitase large subunit 09105 Amino acid metabolism 00300 Lysine biosynthesis K16792 aksD; methanogen homoaconitase large subunit Enzymes [BR:ko01000] 4. Lyases 4.2 Carbon-oxygen lyases 4.2.1 Hydro-lyases 4.2.1.114 methanogen homoaconitase K16792 aksD; methanogen homoaconitase large subunit Enzymes of 2-oxocarboxylic acid metabolism [br01601.html] 2-Oxoacid chain elongation K16792 DBLINKS COG: COG0065 GENES DLM: DPPLL_22760 NCM: QNK12_15500 ALKG: MOJ78_01920 PLZH: C0638_11390 DBC: MFMK1_002474 SEDM: RBQ61_16875 MMAX: LCQ47_06430 FCZ: IMF26_08905 FBS: N510_000758(hacA) NAEI: GCM126_09540 AACD: LWP59_12505 RRS: RoseRS_1053 RCA: Rcas_3474 CAU: Caur_0329 CHL: Chy400_0354 CAG: Cagg_3602 HAU: Haur_3302 LEK: hrd7_27860(leuC_2) KBB: ccbrp13_35940 PMET: G4Y79_18425 DRA: DR_1610 DGE: Dgeo_1156 DDR: Deide_13470 DMR: Deima_1355 DGO: DGo_CA1306 DPD: Deipe_2764 DSW: QR90_09055 DCH: SY84_02060 DPU: SU48_08715 DEZ: DKM44_08505 DWU: DVJ83_05635 DFC: DFI_07080 DEIN: DAAJ005_11930 DGA: DEGR_14160(leuC1) DPH: EHF33_05185 DRB: N0D28_07410 DAH: DAETH_14730(leuC1) DAQU: M8445_12290 DTAE: LAJ19_06390 DMB: E5F05_13870 DSC: ABOD76_16825 TRA: Trad_1389 TTH: TT_C1547 TTJ: TTHA1911(TTHA1911) TTS: Ththe16_1911 TTL: TtJL18_1993 TSC: TSC_c01880(hacA) THC: TCCBUS3UF1_21070 TOS: Theos_1937 TAQ: TO73_0094 TPAR: AV541_01240 TBC: A0O31_00874 TANT: KNN15_05110 MRB: Mrub_2728 MRE: K649_08895 MTAI: Mtai_v1c23270 MSV: Mesil_0442 OPR: Ocepr_1780 MHD: Marky_0672 SCOR: J3U87_19130 ARAM: KAR29_05985 MJA: MJ_1003 MFE: Mefer_1231 MVU: Metvu_1303 MFS: MFS40622_1618 MIF: Metin_0516 MJH: JH146_0954 MESG: MLAUSG7_0432(hacA) MESA: MLASG1_0006(hacA) MIG: Metig_0807 MMP: MMP1480 MMQ: MmarC5_0098 MMX: MmarC6_1194 MMZ: MmarC7_0724 MMD: GYY_08235 MMAK: MMKA1_17030(leuD) MMAO: MMOS7_15860(leuD) MMAD: MMJJ_13590(dmdA_1) MAE: Maeo_0311 MVN: Mevan_0789 MVO: Mvol_1623 MOK: Metok_0062 METF: CFE53_05095 MTH: MTH_1631 MMG: MTBMA_c02160(leuC1) MWO: MWSIV6_0177(hacA) MTEE: MTTB_13810 METC: MTCT_1490 METE: tca_01581(dmdA_2) METZ: METMT2_1470 METK: FVF72_03470 MTHM: FZP57_00775 METJ: FZP68_05785 MST: Msp_1100(leuC2) METB: AW729_10315 MEIS: PXD04_02105(hacA) MRU: mru_0384(aksD) MSI: Msm_0723 MEB: Abm4_0180(aksD) MMIL: sm9_2161(aksD) MEYE: TL18_01065 MOL: YLM1_0055 MARO: MarbSA_13800 METV: K4897_04160 MEL: Metbo_2070 MEW: MSWAN_0570 METH: MBMB1_0289(leuC2) MFC: BRM9_1986(aksD) MFI: DSM1535_0178(leuC2) MCUB: MCBB_0567(hacA) MSUB: BK009_11610 METN: BK008_07185 METT: CIT01_06840 METO: CIT02_05440 MEME: HYG87_07560 MFEG: GCM10025860_11490 MEER: NKF70_09715(hacA) MFV: Mfer_0965 MKA: MK1208(leuC_2) MBA: Mbar_A1961 MBY: MSBRM_0704 MBW: MSBRW_2776 MBAR: MSBR2_1672 MBAK: MSBR3_1673 MAC: MA_3085(leuC) MMA: MM_0409 MMAZ: MmTuc01_0417 MMJ: MSMAS_0894 MMAC: MSMAC_0883 MVC: MSVAZ_1170 MEK: MSKOL_1122 MLS: MSLAZ_2100 METM: MSMTP_2281 MEF: MSWH1_0957 MEQ: MSWHS_1027 MSJ: MSSAC_2956 MSZ: MSSIH_2594 MSW: MSSIT_2634 MTHR: MSTHT_2523 MTHE: MSTHC_0762 MHOR: MSHOH_1131 MFZ: AOB57_002735 MBU: Mbur_2263(hacA) MMET: MCMEM_0412 MELO: J7W08_00085 MMH: Mmah_0418 MHAZ: BHR79_01390 MPOT: BKM01_07045 MEV: Metev_1371 MZH: Mzhil_0725 MPY: Mpsy_2821 MZI: HWN40_08640 MMAV: RE476_01605 MSEB: RE474_11260 MHZ: Metho_0694 MEHF: MmiHf6_03300(leuC_1) MEES: MmiEs2_06150(leuC_1) MTP: Mthe_0788 MCJ: MCON_0444(leuC1) MHI: Mhar_1525 MHU: Mhun_1800 MRTJ: KHC33_05410 MLA: Mlab_0233 MEM: Memar_0634 MBG: BN140_1717(leuC3) MEMA: MMAB1_2209(leuC) MCHK: MchiMG62_07640 MSUM: OH143_09890 MRC: R6Y96_02545 MPI: Mpet_2489 MEND: L6E24_09225 MEFW: F1737_00610 MAQE: RJ40_05980 MFK: E2N92_06110 MOU: OU421_03655 MESB: L1S32_07255 MANQ: L1994_01085 MBN: Mboo_0599 MFO: Metfor_2592 MPL: Mpal_2143 MPD: MCP_1961 MEZ: Mtc_1559(leuC-2) RCI: RCIX2646(leuC-2) SSAI: N0B31_20520 MEUZ: KRP56_01645 LOB: NEF87_001443 REFERENCE PMID:18765671 AUTHORS Drevland RM, Jia Y, Palmer DR, Graham DE TITLE Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis. JOURNAL J Biol Chem 283:28888-96 (2008) DOI:10.1074/jbc.M802159200 SEQUENCE [mja:MJ_1003] ///