ENTRY       K05299                      KO
SYMBOL      fdhA
NAME        formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]
PATHWAY     map00680  Methane metabolism
            map00720  Other carbon fixation pathways
            map01100  Metabolic pathways
            map01120  Microbial metabolism in diverse environments
            map01200  Carbon metabolism
MODULE      M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
REACTION    R00134  formate:NADP+ oxidoreductase
BRITE       KEGG Orthology (KO) [BR:ko00001]
             09100 Metabolism
              09102 Energy metabolism
               00720 Other carbon fixation pathways
                K05299  fdhA; formate dehydrogenase (NADP+) alpha subunit
               00680 Methane metabolism
                K05299  fdhA; formate dehydrogenase (NADP+) alpha subunit
            Enzymes [BR:ko01000]
             1. Oxidoreductases
              1.17  Acting on CH or CH2 groups
               1.17.1  With NAD+ or NADP+ as acceptor
                1.17.1.10  formate dehydrogenase (NADP+)
                 K05299  fdhA; formate dehydrogenase (NADP+) alpha subunit
DBLINKS     COG: COG3383
            GO: 0047899
GENES       CCAX: KZ686_11545(fdhF)
            GSU: GSU0509(sfrA)
            GSK: KN400_0498(sfrA)
            GME: Gmet_3022(sfrA)
            GPI: GPICK_13835
            GBZ: JZM60_03195
            GEM: GM21_0673
            GEB: GM18_3695
            GEF: FO488_01565
            GEV: GSVR_06160(sfrA)
            GEC: GEO60473_34020
            GUR: Gura_3639
            GEO: Geob_1608(sfrA)
            GLO: Glov_0661
            TAMM: GEAMG1_0198(sfrA)
            GBM: Gbem_0660(sfrA)
            GBN: GEOBRER4_06670(sfrA)
            GER: KP004_02575
            GSUB: KP001_12875
            GNT: KP003_02210
            GPL: M1B72_18390
            GSB: GSUB_01600
            GHC: L9S41_11605
            DEU: DBW_0667
            DVE: DESUT3_04350(sfrA)
            DEP: AOP6_2711(sfrA)
            DES: DSOUD_3426
            PSYF: N1030_00160(fdhF)
            PNW: SYK_15590
            DBA: Dbac_0167
            DESU: NLA06_12110(fdhF)
            DPS: DP0682
            DBK: DGMP_17720
            DDU: GF1_09750
            ELAX: KKHLCK_05175
            DAL: Dalk_2557 Dalk_2597
            DAT: HRM2_16890(fdhA6)
            DTO: TOL2_C28850(fdhA2)
            DALK: DSCA_49620 DSCA_51850
            DMM: dnm_034450 dnm_095740
            DEK: DSLASN_10670
            DAO: Desac_1071 Desac_2111
            DTI: Desti_2931
            DBR: Deba_0488
            DMP: FAK_07840 FAK_16570
            TAV: G4V39_01635
            TMAI: FVE67_00210
            DHR: LGS26_01895(fdhF)
            CMIC: caldi_03270
            DSY: DSY3968(fdhF)
            DHD: Dhaf_1398
            DDH: Desde_1318
            DDL: Desdi_1184
            SGY: Sgly_2685
            DOR: Desor_0661 Desor_4477
            DAI: Desaci_0777
            DMI: Desmer_0214 Desmer_0713
            DED: DHBDCA_p1614
            DEC: DCF50_p1622
            DRS: DEHRE_11885
            DCA: Desca_2053
            DAE: Dtox_3503 Dtox_3507
            DAU: Daud_0104
            FWA: DCMF_14065
            AACX: DEACI_1377
            TJR: TherJR_0670 TherJR_0942
            DGI: Desgi_2136 Desgi_3847
            HMO: HM1_1745(fdhA)
            AWI: CHL1_000121(fdhF)
            CTHM: CFE_2215
            CHY: CHY_0733(fdhA)
            ADG: Adeg_0156 Adeg_0334
            MTA: Moth_2312(fdhA)
            MTHO: MOTHE_c23870(fdhF3)
            MTHZ: MOTHA_c24590(fdhF3)
            TOC: Toce_0785
            NTH: Nther_0100
            AAR: Acear_2299
            CAD: Curi_c16640(fdhB)
            KPAR: JL105_10655(fdhF)
            MANA: MAMMFC1_01801
            STED: SPTER_40200(napA_1)
            SSPH: SPSPH_014220(fdhF_5)
            SOVA: SOV_14460(fdhF_1) SOV_46170
            SSID: SPSIL_019530(fdhF_1) SPSIL_050700(napA_4)
            DLY: Dehly_0227
            DETH: HX448_07080(fdhF)
            LMAJ: GKN94_07055
            CALL: OZ401_003579
            ULI: ETAA1_06170
            BROC: IPI25_00230 IPI25_07710(fdhF) IPI25_08630(fdhF)
            BPIT: BPIT_05580 BPIT_26950
            JET: L3J17_07505 L3J17_14530(fdhF)
            ADIN: H7849_06915(nuoG)
            ARAM: KAR29_00265(fdhF)
            ASAC: ATHSA_0203
            MSCH: N508_001026(sfrA)
            DTP: JZK55_05530(nuoG-1_1) JZK55_11790 JZK55_19460(fdhA)
            NKF: Nkreftii_003503 Nkreftii_004097
            NTI: DNFV4_00402 DNFV4_00911
            NALL: PP769_05445 PP769_08770(nuoG)
            NNEO: PQG83_16650 PQG83_19995(nuoG)
            NLI: G3M70_15040
            NVA: G3M78_09375
            MTH: MTH_1552
            MMG: MTBMA_c01380(fdhA1)
            MTEE: MTTB_15350
            METC: MTCT_1417
            METE: tca_01501(fdhF_2)
            METZ: METMT2_0015
            METK: FVF72_03860
            METJ: FZP68_05395
            MEL: Metbo_2515
            METT: CIT01_06250
            MEME: HYG87_07080(fdhF)
            MFEG: GCM10025860_09010
            MEER: NKF70_07300(fdhF)
            MTP: Mthe_0915
            LOB: NEF87_003197
REFERENCE   PMID:6822536
  AUTHORS   Yamamoto I, Saiki T, Liu SM, Ljungdahl LG
  TITLE     Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein.
  JOURNAL   J Biol Chem 258:1826-32 (1983)
REFERENCE   PMID:18631365
  AUTHORS   Pierce E, Xie G, Barabote RD, Saunders E, Han CS, Detter JC, Richardson P, Brettin TS, Das A, Ljungdahl LG, Ragsdale SW
  TITLE     The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum).
  JOURNAL   Environ Microbiol 10:2550-73 (2008)
            DOI:10.1111/j.1462-2920.2008.01679.x
///