ENTRY K00198 KO SYMBOL cooS, acsA NAME anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4] PATHWAY map00633 Nitrotoluene degradation map00680 Methane metabolism map00720 Other carbon fixation pathways map01100 Metabolic pathways map01120 Microbial metabolism in diverse environments map01200 Carbon metabolism MODULE M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway) REACTION R07157 carbon-monoxide,water:ferredoxin oxidoreductase R08034 BRITE KEGG Orthology (KO) [BR:ko00001] 09100 Metabolism 09102 Energy metabolism 00720 Other carbon fixation pathways K00198 cooS, acsA; anaerobic carbon-monoxide dehydrogenase catalytic subunit 00680 Methane metabolism K00198 cooS, acsA; anaerobic carbon-monoxide dehydrogenase catalytic subunit 09111 Xenobiotics biodegradation and metabolism 00633 Nitrotoluene degradation K00198 cooS, acsA; anaerobic carbon-monoxide dehydrogenase catalytic subunit Enzymes [BR:ko01000] 1. Oxidoreductases 1.2 Acting on the aldehyde or oxo group of donors 1.2.7 With an iron-sulfur protein as acceptor 1.2.7.4 anaerobic carbon monoxide dehydrogenase K00198 cooS, acsA; anaerobic carbon-monoxide dehydrogenase catalytic subunit DBLINKS COG: COG1151 GO: 0043885 GENES CAMA: F384_12620 TOE: QMG90_04310(cooS) SLIG: GTU79_09640(cooS) AVN: Avin_04490(cooS) AVL: AvCA_04490(cooS) AVD: AvCA6_04490(cooS) ACX: Achr_4450(cooS) SCHK: GII14_05600(cooS) SPSR: EGC80_02395(cooS) TMB: Thimo_0223 NPV: OHM77_01955(cooS) RPC: RPC_4498 RLAC: QMO75_13075 SABI: PBT88_09965(cooS) RRU: Rru_A1427 RRF: F11_07370 CCV: CCV52592_1131(codH) CCO: CCC13826_0236(codH) CGRA: CGRAC_1999 SULT: FA592_03290(cooS) GSU: GSU2098(cooS) GME: Gmet_1902(cooS) GPI: GPICK_01000 GPICK_11385 GBZ: JZM60_09735(cooS) JZM60_15465(cooS) GEV: GSVR_24640 GEC: GEO60473_15420(cooS) GUR: Gura_0618 GEO: Geob_0362(cooS-1) Geob_1046(cooS-2) GBM: Gbem_0072(cooS-2) Gbem_1736(cooS-1) GER: KP004_20870(cooS) GSUB: KP001_15480(cooS) GNT: KP003_20810(cooS) GPL: M1B72_20990(cooS) GSB: GSUB_09760 PCA: Pcar_0057(cooS-2) Pcar_0888(cooS-1) PEF: A7E78_09750 DEU: DBW_0138 DVE: DESUT3_02300 DES: DSOUD_1182(cooS) DDS: Ddes_0382 DEF: CNY67_12835(cooS) DFL: DFE_2686 PSYF: N1030_14405(cooS) DSB: LN040_10065(cooS) LN040_11210(cooS) LN040_11220 DMA: DMR_25780 DCB: C3Y92_11905(cooS) DDE: Dde_3028 DMS: E8L03_07465(cooS) DSA: Desal_2508 DAF: Desaf_2842 DAS: Daes_0529 DPI: BN4_11760(cooS) BN4_20190(cooS) DEJ: AWY79_01565 AWY79_06530 AWY79_06540 PPRF: DPRO_1606(cooS) DPRO_3530 DDN: DND132_2520 PSEF: PSDVSF_24750(cooS) PPOR: JCM14722_28790(cooS) PNW: SYK_25290(cooS) PTHE: LF599_01455(cooS) DSX: GD604_08985(cooS) DSD: GD606_18530(cooS) PBIZ: LWC08_02100(cooS) LWC08_04395(cooS) DVU: DVU_2098(cooS) DVL: Dvul_1133 DVM: DvMF_2233 DVG: Deval_1949 CLIH: KPS_002595(cooS) DBA: Dbac_0934 DRT: Dret_1234 DSF: UWK_01293 UWK_03164 DLM: DPPLL_25950(cooS_1) DPPLL_26600(cooS_2) DAK: DaAHT2_0337 DaAHT2_0827 DBK: DGMP_17830(cooS_1) DGMP_17900(cooS_2) DDU: GF1_01790(cooS_1) GF1_14190(cooS_2) ECOM: QTN59_00690(cooS) QTN59_02735(cooS) EAJ: Q3M24_13015(cooS) Q3M24_14560(cooS) ELAX: KKHLCK_06215(cooS) EAQ: LDFHOB_06900(cooS) DOL: Dole_1461 Dole_3185 DAL: Dalk_0680 Dalk_2379 DAT: HRM2_16670(cdhA) HRM2_41010(cdh1) HRM2_43440(cdh2) DTO: TOL2_C00990(cdh1) TOL2_C11820(cdhA) TOL2_C38110(cooS) DOV: DSCO28_32360(cooS_1) DSCO28_36040(cooS_2) DSCO28_44770 DSCO28_59740(cooS_3) DWD: DSCW_28520(cooS_1) DSCW_41580(cooS_2) DSCW_47510(cooS_3) DALK: DSCA_26710(cooS_1) DSCA_27610(cooS_2) DSCA_28100(cooS_3) DESB: BuS5_02609 DML: Dmul_09300(cooS1) Dmul_19100(cooS2) Dmul_30840(cdhA) DLI: dnl_13210(cdhA) dnl_20660(cooS) DMM: dnm_013300(cdhA1) dnm_058880(cooS) dnm_066390(cdhA2) DEK: DSLASN_16750(cooS_1) DSLASN_29000(cooS_2) DSLASN_47710(cooS_3) DAO: Desac_0166 Desac_1966 Desac_2050 DTI: Desti_0232 SFU: Sfum_2566 Sfum_2875 DAX: FDQ92_02155(cooS) FDQ92_06245(cooS) DBR: Deba_0241 DMP: FAK_40980(cooS) FAK_42020(cooS) TID: Thein_1422 Thein_2190 TOP: TOPB45_0398 CTHI: THC_1754 TAV: G4V39_00810(cooS) G4V39_01690(cooS) TMAI: FVE67_00270(cooS) DHR: LGS26_01950(cooS) GMC: GY4MC1_1807 GTH: Geoth_1875 PTL: AOT13_13405 BBEV: BBEV_2326(cooS1) PDU: PDUR_14040 PSOP: KP014_17220(cooS) CAC: CA_C0116 CA_C2498 CAE: SMB_G0117(cooS) SMB_G2533 CAY: CEA_G0117 CEA_G2512 CTC: CTC_01156 CTET: BN906_01229 CNO: NT01CX_0669(cooS) CBO: CBO1331 CBO2218 CBA: CLB_1359 CLB_2157 CBH: CLC_1369 CBY: CLM_1506 CLM_2421 CBL: CLK_0775 CLK_1658 CBB: CLD_2358 CLD_3226 CBI: CLJ_B1446 CLJ_B2428 CBN: CbC4_2402(cooS) CBF: CLI_1426 CLI_2267 CBM: CBF_1402 CBF_2255 CBJ: H04402_01401 H04402_02230 CBE: Cbei_3020 Cbei_5054 CBZ: Cbs_3020 Cbs_5054 CBEI: LF65_03401 LF65_05731 CKL: CKL_2148 CKR: CKR_1887 CLJ: CLJU_c09110(cooS1) CLJU_c17910(cooS2) CLJU_c37670(codH) CCB: Clocel_0365 Clocel_1516 Clocel_2587 Clocel_4231 CLB: Clo1100_1430 Clo1100_3687 CSR: Cspa_c16740(cooS1) Cspa_c21120(cooS2) Cspa_c57670(cooS3) CPAS: Clopa_0057 Clopa_1484 Clopa_2128 Clopa_3232 CPAT: CLPA_c05080(cooS) CLPA_c34390(cooS1) CPAE: CPAST_c05080(cooS) CPAST_c34390(cooS1) CSB: CLSA_c11710(cooS1) CLSA_c14830(cooS2) CAH: CAETHG_3005(cooS) CAETHG_3899(cooS) CLT: CM240_0400 CSQ: CSCA_1153 CSCA_1513 CSCA_3645 CSCA_4539 CLD: CLSPO_c13520(cooS1) CLSPO_c22620(cooS2) CACE: CACET_c09110(acsA1) CACET_c10200(acsA2) CACET_c16200 CACET_c26140(acsA3) CCK: Ccar_07140 Ccar_08590 Ccar_18845 Ccar_23090 CTYK: CTK_C21760(cooS) CEU: A7L45_14975 CFM: BJL90_04040 BJL90_08730 BJL90_10555 BJL90_11075 BJL90_13810 BJL90_18885 CARG: RSJ17_07130 RSJ17_07755 CDRK: B9W14_01390 B9W14_11700 B9W14_13030 B9W14_22310 CDY: F3K33_15405(cooS) F3K33_25905(cooS) CCOH: SAMEA4530647_0946(cooS1_1) CLOS: DMR38_04285(cooS) DMR38_08960(cooS) DMR38_18780(cooS) DMR38_21405(cooS) CMAH: C1I91_10775(cooS) C1I91_16460(cooS) CRW: CROST_003140(cooS1) CROST_009140 CFB: CLFE_039580(cooS2) CLFE_045400(cooS1) CAUN: CLAUR_020030(cooS2) CLAUR_026960(cooS1) CTAG: LL095_00515(cooS) CTHD: CDO33_08275(cooS) HHW: NCTC503_01567(cooS1) SARJ: HH195_01185(cooS) CTH: Cthe_2801 CTX: Clo1313_0390 CCL: Clocl_0520 Clocl_0806 CCE: Ccel_0438 Ccel_2918 RHER: EHE19_006575(cooS) RPAY: P0092_07465(cooS) P0092_19815(cooS) CSS: Cst_c19650(cooS1) CSD: Clst_1883 RAL: Rumal_3736 RUM: CK1_12690 RGV: NQ502_01510(cooS) NQ502_15320(cooS) PETR: QKW49_06145(cooS) DSY: DSY1653 DSY2630 DSY4173 DSY4442 DHD: Dhaf_0882 Dhaf_1166 Dhaf_2798 Dhaf_3792 DDH: Desde_1134 Desde_2256 Desde_3264 DDL: Desdi_0655 Desdi_0934 Desdi_1922 DMT: DESME_03525 DESME_07325 SGY: Sgly_2814 DOR: Desor_0421 Desor_3274 Desor_4181 Desor_4446 DAI: Desaci_0260 Desaci_0709 Desaci_2975 DMI: Desmer_0456 Desmer_1790 Desmer_2536 Desmer_3209 Desmer_3478 DED: DHBDCA_p230(cooS1) DEC: DCF50_p290(cooS1) DRS: DEHRE_00735 DCA: Desca_0349 Desca_1148 Desca_1990 DRM: Dred_0652 DRU: Desru_0859 Desru_3320 DFG: B0537_03940 DAE: Dtox_1270 Dtox_2327 Dtox_2933 Dtox_3780 DKU: Desku_1492 Desku_2150 Desku_2787 DAU: Daud_0870 TFR: BR63_06565(cooS) FWA: DCMF_02985 DCMF_05870 DCMF_16840 AACX: DEACI_0147 DEACI_1162 DEACI_2511 TJR: TherJR_1157 TherJR_1937 TherJR_2144 TherJR_2959 DGI: Desgi_0522 Desgi_1185 Desgi_2052 Desgi_2753 Desgi_3080 HCV: FTV88_2859 FTV88_3326 ELM: ELI_3603 EMT: CPZ25_018705(cooS) ELIM: B2M23_08400 AWO: Awo_c10740(acsA) Awo_c19050(cooS) AWI: CHL1_001821(cooS) CHL1_002703(cooS) ALKA: J0B03_11230(cooS) ACAE: HYG86_07690(cooS) HYG86_14090(cooS) HFV: R50_0939(cooS) CTHM: CFE_0163 CFE_0173 CFE_0653 CFE_1617 CFE_1666 CFE_1919 ROB: CK5_28700 BYL: A4V09_05450 A4V09_05810 BHAN: CGC63_06525(cooS) CGC63_07980(cooS) BLAU: DQQ01_10205(cooS) BPRO: PMF13cell1_00639(cooS1_1) PMF13cell1_04203(cooS) PMF13cell1_04285(cooS1_2) BLAB: EYS05_16735(cooS) BLIQ: INP51_05945(cooS) BWX: NQ550_13525(cooS) BMAS: LK422_06245(cooS) BLAR: LC508_02755(cooS) LC508_03345(cooS) LC508_10485(cooS) BLUI: Blut17040_19240(cooS) BCOC: BLCOC_29830(cooS1_1) BLCOC_32200(cooS) BLCOC_33130(cooS1_2) BHV: BLHYD_10750(cooS1_1) BLHYD_15380(cooS1_2) BLHYD_31740(cooS1_3) LACY: A4V08_01520 CHYL: CE91St63_06990 CSH: Closa_0921 LXA: OW255_01080(cooS) OW255_13590(cooS) LGG: QJR73_11450(cooS) EHL: EHLA_2243 ACEL: acsn021_07870 RGN: RGna_12250(cooS) CBOL: CGC65_03955(cooS) CGC65_24000(cooS) CASP: NQ535_04635(cooS) QDO: H9Q78_01480(cooS) H9Q78_02995(cooS) WHJ: H9Q79_03145(cooS) H9Q79_03495(cooS) MFOR: NQ534_19140(cooS) AHB: bsdtb5_25690 STOM: QU660_06420(cooS) LBX: lbkm_0343 AMIJ: EQM06_02755(cooS) AMIC: Ami3637_03990(cooS) Ami3637_14435 ABUT: Ami103574_08595(cooS) Ami103574_09485 AMT: Amet_1177 Amet_2016 Amet_3764 GFE: Gferi_05255 Gferi_06375 Gferi_11835 Gferi_24855 PBIF: KXZ80_13960(cooS) KXZ80_14960(cooS) PSOR: RSJ16_15770 CDF: CD630_01740(cooS) CD630_07160(cooS1) PDC: CDIF630_00296 CDIF630_00832(cooS) CDC: CD196_0188 CD196_0661(cooS) CDL: CDR20291_0175 CDR20291_0643(cooS) PDF: CD630DERM_01740(cooS) CD630DERM_07160(cooS1) ROC: HF520_11320(cooS) RIL: CRIB_2171 RHOM: FRIFI_1555 FRIFI_2478 FRIFI_2658 PHX: KGNDJEFE_00543(cooS) TEM: JW646_03340(cooS) JW646_10835(cooS) JW646_19155(cooS) TGC: L0P85_04965(cooS) L0P85_16925(cooS) TMY: TEMA_00050(cooS) TEMA_26170(acsA) TPET: TPHSE_11890(cooS1) TPHSE_37400(acsA) TEB: T8CH_0649(cooS) T8CH_1211(cooS) T8CH_3032(cooS) THYR: P4S50_13930(cooS) IBR: NQ514_02295(cooS) NQ514_13145(cooS) CST: CLOST_1160 TTE: TTE1708 TKI: TKV_c08080(cooS) TKV_c20100(acsA) CHY: CHY_0034(cooSV) CHY_0085(cooSII) CHY_0736(cooSIV) CHY_1824(cooSI) ADG: Adeg_0335 TPZ: Tph_c05730(cooS1) Tph_c15180(acsB) AAUT: ACETAC_02795(cooS) ACETAC_10650(cooS) MTA: Moth_1203 Moth_1972 MTHO: MOTHE_c11790 MOTHE_c20130(cooS1) MTHZ: MOTHA_c12660 MOTHA_c20910(cooS1) MHUI: MHLNE_12700(acsA) DBC: MFMK1_000383(cooS) MFMK1_001371(cooS) MFMK1_002344(cooS) MFMK1_002513(cooS) TEP: TepRe1_0548 TAE: TepiRe1_0598(cooS) BACG: D2962_12415(cooS) TOC: Toce_0335 Toce_0761 Toce_0800 NTH: Nther_0860 NCD: ACONDI_00123(cooS2) ACONDI_01147(cooS1) ACONDI_02970 HALS: D7D81_07270(cooS) D7D81_07945(cooS) IFN: GM661_04805(cooS) GM661_05400(cooS) AAR: Acear_0983 Acear_1305 HHL: Halha_1234 CAD: Curi_c06440(cooS) CAZO: G3A45_00240(cooS) TIS: P3962_01825(cooS) VPR: Vpar_0209 VAT: B7L28_00930 VRM: 44547418_00230(cooS2) VDN: NCTC11831_00196(cooS1) VNK: VEIT17_01990 VRG: OKW85_01120(cooS) MMAX: LCQ47_06945(cooS) SSG: Selsp_2016 PUF: UFO1_0648 UFO1_2774 PFT: JBW_00105 JBW_04289 MANA: MAMMFC1_00477 MAMMFC1_00822(cooS) MAMMFC1_02734(cooS2) STED: SPTER_01630 SPTER_04690(cooS2_1) SPTER_06840(cooS2_2) SPTER_13670 SSPH: SPSPH_008210(cooS1_1) SPSPH_010530(cooS1_2) SPSPH_013870 SOVA: SOV_14240 SOV_30560(cooS2) SSID: SPSIL_019310 SPSIL_033400(cooS1) SPSIL_054700(cooS2) CALK: HUE98_10145(cooS) HUE98_15625(cooS) HUE98_15635(cooS) CSC: Csac_0400 CHD: Calhy_0239 CKI: Calkr_0175 CLC: Calla_2155 CDAN: SOJ16_002586(cooS) TNR: Thena_0036 TACI: TDSAC_0035 KST: KSMBR1_1326(cdh_acsA) KSMBR1_3765(acsA_2) BROC: IPI25_11085(cooS) BPIT: BPIT_02260 JET: L3J17_07160(cooS) TPI: TREPR_3069(cooS) TAZ: TREAZ_1535(cooS_2) TREAZ_1650(cooS_1) CPOR: BED41_06285 TOH: BCB71_06635(cooS) CPC: Cpar_1193 CPH: Cpha266_0149 PROS: CHL67_00350 PROW: OO006_00250 PROI: OO005_00240 PMX: PERMA_0106(cooS) TAM: Theam_1337 DTE: Dester_0417 Dester_0833 DIN: Selin_2012 DTP: JZK55_05490(cooS) MJA: MJ_0728 MVU: Metvu_0628 MFS: MFS40622_1444 MJH: JH146_1155 MESG: MLAUSG7_0241(cooS) MESA: MLASG1_1434(cooS) MIG: Metig_0288 Metig_0357 MVO: Mvol_0200 MKA: MK0536 AFU: AF_1849 AFG: AFULGI_00021030 AST: Asulf_01231 FPL: Ferp_2369 Ferp_2562 GAC: GACE_0127 GAH: GAH_01577 TON: TON_1018 TGA: TGAM_0824(cooS) TBA: TERMP_01153 THA: TAM4_1067 TAM4_582 THS: TES1_1211 TGY: X802_05885 TBS: A3L01_08235 THH: CDI07_07345(cooS) TSL: A3L11_01585 TPRF: A3L09_01360 TRL: A3L10_07625 MBA: Mbar_A3525 Mbar_A3717 MBY: MSBRM_1052 MSBRM_2317 MBW: MSBRW_1019 MSBRW_1209 MBAR: MSBR2_0095 MSBR2_1359 MBAK: MSBR3_0095 MAC: MA_1309(cooS) MA_3282(cooS) MMA: MM_0121 MM_2301 MMAZ: MmTuc01_0129 MmTuc01_2347 MMJ: MSMAS_1212 MSMAS_2399 MMAC: MSMAC_2048 MSMAC_2550 MVC: MSVAZ_2289 MSVAZ_2495 MEK: MSKOL_2294 MSKOL_2507 MLS: MSLAZ_0996 MSLAZ_1465 METM: MSMTP_0809 MSMTP_1179 MEF: MSWH1_2253 MEQ: MSWHS_2820 MSWHS_3011 MSJ: MSSAC_0985 MSZ: MSSIH_0886 MSW: MSSIT_0920 MTHR: MSTHT_0128 MTHE: MSTHC_0600 MHOR: MSHOH_2496 MSHOH_3023 MSHOH_3042 MPY: Mpsy_0694 MZI: HWN40_01045(cooS) MMAV: RE476_10120(cooS) MSEB: RE474_06710(cooS) MHZ: Metho_1412 MTP: Mthe_1216 Mthe_1341 MCJ: MCON_2865(cooS) MHI: Mhar_1630 MHU: Mhun_1272 MRTJ: KHC33_06770(cooS) KHC33_13060(cooS) MBG: BN140_2260(cooS) MEMA: MMAB1_2986(cooS) MCHK: MchiMG62_13740(cooS) MPI: Mpet_0907 MEND: L6E24_05895(cooS) MEFW: F1737_05325(cooS) F1737_06810(cooS) MAQE: RJ40_02225(cooS) MFK: E2N92_01250(cooS) MESB: L1S32_10345(cooS) L1S32_11700(cooS) MBN: Mboo_0884 MPL: Mpal_0842 HAHS: HSRCO_0891(cooS) SAIM: K0C01_08745(cooS) HDS: HSR122_2762 HDF: AArcSl_0878(cooS) MEAM: MU439_06845(cooS) MEAE: QEN48_03310(cooS) MEAR: Mpt1_c02980 MEUZ: KRP56_03685(cooS) PARE: PYJP_17370(cooS) TCB: TCARB_0870 KCR: Kcr_0762 BARC: AOA65_1716(cdhA) REFERENCE PMID:11024270 AUTHORS Gonzalez JM, Robb FT TITLE Genetic analysis of Carboxydothermus hydrogenoformans carbon monoxide dehydrogenase genes cooF and cooS. JOURNAL FEMS Microbiol Lett 191:243-7 (2000) DOI:10.1111/j.1574-6968.2000.tb09346.x SEQUENCE [chy:CHY_0085] REFERENCE PMID:12386327 AUTHORS Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL TITLE A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. JOURNAL Science 298:567-72 (2002) DOI:10.1126/science.1075843 SEQUENCE [mta:Moth_1203] ///