ENTRY ko04016 Pathway NAME MAPK signaling pathway - plant DESCRIPTION Mitogen-activated protein kinase (MAPK) cascades, the evolutionarily conserved signaling modules in all eukaryotes, serve in transducing extracellular signals to the nucleus or cytoplasm for appropriate cellular responses, including cell division, differentiation, programmed cell death, and adaption to various stresses. In plant, several cascades are triggered by different biotic and abiotic stress stimuli such as pathogen infection, wounding, low temperature, drought, osmotic shock, high salinity, and reactive oxygen species. MAPK pathways also play pivotal roles in processes such as hormonal and developmental signaling. Multiple functional pathways initiated from distinct receptors often share the same kinase components while maintaining their signaling specificity. In contrast to those of animals and fungi, all the plant MAPK genes that have been reported belong to extracellular signal-regulated kinase (ERK) subfamily. CLASS Environmental Information Processing; Signal transduction PATHWAY_MAP ko04016 MAPK signaling pathway - plant DBLINKS GO: 0000165 ORTHOLOGY K00940 ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6] K02183 CALM; calmodulin K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6] K13413 MKK4_5; mitogen-activated protein kinase kinase 4/5 [EC:2.7.12.2] K13414 MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] K13416 BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1] K13420 FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [EC:2.7.11.1] K13422 MYC2; transcription factor MYC2 K13423 WRKY25; WRKY transcription factor 25 K13424 WRKY33; WRKY transcription factor 33 K13425 WRKY22; WRKY transcription factor 22 K13426 WRKY29; WRKY transcription factor 29 K13447 RBOH; respiratory burst oxidase [EC:1.6.3.- 1.11.1.-] K13449 PR1; pathogenesis-related protein 1 K14496 PYL; abscisic acid receptor PYR/PYL family K14497 PP2C; protein phosphatase 2C [EC:3.1.3.16] K14498 SNRK2; serine/threonine-protein kinase SRK2 [EC:2.7.11.1] K14509 ETR, ERS; ethylene receptor [EC:2.7.13.-] K14510 CTR1; serine/threonine-protein kinase CTR1 [EC:2.7.11.1] K14512 MPK6; mitogen-activated protein kinase 6 [EC:2.7.11.24] K14513 EIN2; ethylene-insensitive protein 2 K14514 EIN3; ethylene-insensitive protein 3 K14515 EBF1_2; EIN3-binding F-box protein K14516 ERF1; ethylene-responsive transcription factor 1 K16224 FRK1; senescence-induced receptor-like serine/threonine-protein kinase K17686 copA, ctpA, ATP7; P-type Cu+ transporter [EC:7.2.2.8] K20535 MPK1_2; mitogen-activated protein kinase 1/2 [EC:2.7.11.24] K20536 MPK3; mitogen-activated protein kinase 3 [EC:2.7.11.24] K20537 MPK7_14; mitogen-activated protein kinase 7/14 [EC:2.7.11.24] K20538 MPK8; mitogen-activated protein kinase 8 [EC:2.7.11.24] K20547 CHIB; basic endochitinase B [EC:3.2.1.14] K20551 MKP2; dual specificity protein phosphatase 1B [EC:3.1.3.16 3.1.3.48] K20553 XRN4; 5'-3' exoribonuclease 4 [EC:3.1.13.-] K20557 VIP1; transcription factor VIP1 K20558 SPCH; transcription factor SPEECHLESS K20559 CYP71B15; dihydrocamalexate/camalexin synthase [EC:1.14.19.52] K20599 SUMM2; NB-LRR protein SUMM2 K20600 MPK4; mitogen-activated protein kinase 4 [EC:2.7.11.24] K20602 MEK1, MKK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] K20603 MKK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] K20604 MKK9; mitogen-activated protein kinase kinase 9 [EC:2.7.12.2] K20605 MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25] K20606 ANP1; mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25] K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] K20714 OXI1; serine/threonine-protein kinase OXI1 [EC:2.7.11.1] K20716 MAPKKK17_18; mitogen-activated protein kinase kinase kinase 17/18 K20717 YDA; mitogen-activated protein kinase kinase kinase YODA [EC:2.7.11.25] K20718 ER; LRR receptor-like serine/threonine-protein kinase ERECTA [EC:2.7.11.1] K20725 MKS1; MAP kinase substrate 1 K20726 TMEM222; transmembrane protein 222 K20727 PDF1.2; defensin-like protein 16 K20728 VSP2; vegetative storage protein 2 K20729 EPF1_2; protein EPIDERMAL PATTERNING FACTOR 1/2 K20772 ACS1_2_6; 1-aminocyclopropane-1-carboxylate synthase 1/2/6 [EC:4.4.1.14] REFERENCE PMID:11875555 AUTHORS Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J TITLE MAP kinase signalling cascade in Arabidopsis innate immunity. JOURNAL Nature 415:977-83 (2002) DOI:10.1038/415977a REFERENCE PMID:12119167 AUTHORS TITLE Mitogen-activated protein kinase cascades in plants: a new nomenclature. JOURNAL Trends Plant Sci 7:301-8 (2002) DOI:10.1016/S1360-1385(02)02302-6 REFERENCE PMID:18570633 AUTHORS Colcombet J, Hirt H TITLE Arabidopsis MAPKs: a complex signalling network involved in multiple biological processes. JOURNAL Biochem J 413:217-26 (2008) DOI:10.1042/BJ20080625 REFERENCE PMID:18692429 AUTHORS Kendrick MD, Chang C TITLE Ethylene signaling: new levels of complexity and regulation. JOURNAL Curr Opin Plant Biol 11:479-85 (2008) DOI:10.1016/j.pbi.2008.06.011 REFERENCE PMID:20441529 AUTHORS Rodriguez MC, Petersen M, Mundy J TITLE Mitogen-activated protein kinase signaling in plants. JOURNAL Annu Rev Plant Biol 61:621-49 (2010) DOI:10.1146/annurev-arplant-042809-112252 REFERENCE PMID:20980831 AUTHORS Taj G, Agarwal P, Grant M, Kumar A TITLE MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways. JOURNAL Plant Signal Behav 5:1370-8 (2010) DOI:10.4161/psb.5.11.13020 REFERENCE PMID:23263767 AUTHORS Meng X, Wang H, He Y, Liu Y, Walker JC, Torii KU, Zhang S TITLE A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation. JOURNAL Plant Cell 24:4948-60 (2012) DOI:10.1105/tpc.112.104695 REFERENCE PMID:25720833 AUTHORS Danquah A, de Zelicourt A, Boudsocq M, Neubauer J, Frei Dit Frey N, Leonhardt N, Pateyron S, Gwinner F, Tamby JP, Ortiz-Masia D, Marcote MJ, Hirt H, Colcombet J TITLE Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana. JOURNAL Plant J 82:232-44 (2015) DOI:10.1111/tpj.12808 ///