ENTRY ko04016 Pathway NAME MAPK signaling pathway - plant DESCRIPTION Mitogen-activated protein kinase (MAPK) cascades, the evolutionarily conserved signaling modules in all eukaryotes, serve in transducing extracellular signals to the nucleus or cytoplasm for appropriate cellular responses, including cell division, differentiation, programmed cell death, and adaption to various stresses. In plant, several cascades are triggered by different biotic and abiotic stress stimuli such as pathogen infection, wounding, low temperature, drought, osmotic shock, high salinity, and reactive oxygen species. MAPK pathways also play pivotal roles in processes such as hormonal and developmental signaling. Multiple functional pathways initiated from distinct receptors often share the same kinase components while maintaining their signaling specificity. In contrast to those of animals and fungi, all the plant MAPK genes that have been reported belong to extracellular signal-regulated kinase (ERK) subfamily. CLASS Environmental Information Processing; Signal transduction PATHWAY_MAP ko04016 MAPK signaling pathway - plant DBLINKS GO: 0000165 ORTHOLOGY K13420 LRR receptor-like serine/threonine-protein kinase FLS2 [EC:2.7.11.1] K13416 brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1] K13414 mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] K20602 mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] K20603 mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] K20600 mitogen-activated protein kinase 4 [EC:2.7.11.24] K20605 mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25] K20599 NB-LRR protein SUMM2 K20725 MAP kinase substrate 1 K13424 WRKY transcription factor 33 K20559 dihydrocamalexate/camalexin synthase [EC:1.14.19.52] K13413 mitogen-activated protein kinase kinase 4/5 [EC:2.7.12.2] K20536 mitogen-activated protein kinase 3 [EC:2.7.11.24] K14512 mitogen-activated protein kinase 6 [EC:2.7.11.24] K20557 transcription factor VIP1 K13449 pathogenesis-related protein 1 K13425 WRKY transcription factor 22 K13426 WRKY transcription factor 29 K16224 senescence-induced receptor-like serine/threonine-protein kinase K20772 1-aminocyclopropane-1-carboxylate synthase 1/2/6 [EC:4.4.1.14] K20714 serine/threonine-protein kinase OXI1 [EC:2.7.11.1] K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] K20606 mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25] K13423 WRKY transcription factor 25 K20607 mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] K20535 mitogen-activated protein kinase 1/2 [EC:2.7.11.24] K20537 mitogen-activated protein kinase 7/14 [EC:2.7.11.24] K14509 ethylene receptor [EC:2.7.13.-] K14510 serine/threonine-protein kinase CTR1 [EC:2.7.11.1] K20726 transmembrane protein 222 K17686 P-type Cu+ transporter [EC:7.2.2.8] K20604 mitogen-activated protein kinase kinase 9 [EC:2.7.12.2] K14514 ethylene-insensitive protein 3 K14513 ethylene-insensitive protein 2 K14515 EIN3-binding F-box protein K20553 5'-3' exoribonuclease 4 [EC:3.1.13.-] K14516 ethylene-responsive transcription factor 1 K20727 defensin-like protein 16 K20547 basic endochitinase B [EC:3.2.1.14] K13422 transcription factor MYC2 K20728 vegetative storage protein 2 K14496 abscisic acid receptor PYR/PYL family K14497 protein phosphatase 2C [EC:3.1.3.16] K14498 serine/threonine-protein kinase SRK2 [EC:2.7.11.1] K20716 mitogen-activated protein kinase kinase kinase 17/18 K03781 catalase [EC:1.11.1.6] K20551 dual specificity protein phosphatase 1B [EC:3.1.3.16 3.1.3.48] K20538 mitogen-activated protein kinase 8 [EC:2.7.11.24] K02183 calmodulin K13447 respiratory burst oxidase [EC:1.6.3.- 1.11.1.-] K20729 protein EPIDERMAL PATTERNING FACTOR 1/2 K20718 LRR receptor-like serine/threonine-protein kinase ERECTA [EC:2.7.11.1] K20717 mitogen-activated protein kinase kinase kinase YODA [EC:2.7.11.25] K20558 transcription factor SPEECHLESS REFERENCE PMID:11875555 AUTHORS Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J TITLE MAP kinase signalling cascade in Arabidopsis innate immunity. JOURNAL Nature 415:977-83 (2002) DOI:10.1038/415977a REFERENCE PMID:12119167 AUTHORS TITLE Mitogen-activated protein kinase cascades in plants: a new nomenclature. JOURNAL Trends Plant Sci 7:301-8 (2002) DOI:10.1016/S1360-1385(02)02302-6 REFERENCE PMID:18570633 AUTHORS Colcombet J, Hirt H TITLE Arabidopsis MAPKs: a complex signalling network involved in multiple biological processes. JOURNAL Biochem J 413:217-26 (2008) DOI:10.1042/BJ20080625 REFERENCE PMID:18692429 AUTHORS Kendrick MD, Chang C TITLE Ethylene signaling: new levels of complexity and regulation. JOURNAL Curr Opin Plant Biol 11:479-85 (2008) DOI:10.1016/j.pbi.2008.06.011 REFERENCE PMID:20441529 AUTHORS Rodriguez MC, Petersen M, Mundy J TITLE Mitogen-activated protein kinase signaling in plants. JOURNAL Annu Rev Plant Biol 61:621-49 (2010) DOI:10.1146/annurev-arplant-042809-112252 REFERENCE PMID:20980831 AUTHORS Taj G, Agarwal P, Grant M, Kumar A TITLE MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways. JOURNAL Plant Signal Behav 5:1370-8 (2010) DOI:10.4161/psb.5.11.13020 REFERENCE PMID:23263767 AUTHORS Meng X, Wang H, He Y, Liu Y, Walker JC, Torii KU, Zhang S TITLE A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation. JOURNAL Plant Cell 24:4948-60 (2012) DOI:10.1105/tpc.112.104695 REFERENCE PMID:25720833 AUTHORS Danquah A, de Zelicourt A, Boudsocq M, Neubauer J, Frei Dit Frey N, Leonhardt N, Pateyron S, Gwinner F, Tamby JP, Ortiz-Masia D, Marcote MJ, Hirt H, Colcombet J TITLE Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana. JOURNAL Plant J 82:232-44 (2015) DOI:10.1111/tpj.12808 ///