ENTRY ko02010 Pathway NAME ABC transporters DESCRIPTION The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD). CLASS Environmental Information Processing; Membrane transport PATHWAY_MAP ko02010 ABC transporters DBLINKS GO: 0043190 0043191 0043192 TC: 3.A.1 ORTHOLOGY K01995 livG; branched-chain amino acid transport system ATP-binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein K01997 livH; branched-chain amino acid transport system permease protein K01998 livM; branched-chain amino acid transport system permease protein K01999 livK; branched-chain amino acid transport system substrate-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] K02001 proW; glycine betaine/proline transport system permease protein K02002 proX; glycine betaine/proline transport system substrate-binding protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein K02007 cbiM; cobalt/nickel transport system permease protein K02008 cbiQ; cobalt/nickel transport system permease protein K02009 cbiN; cobalt/nickel transport protein K02010 afuC, fbpC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] K02011 afuB, fbpB; iron(III) transport system permease protein K02012 afuA, fbpA; iron(III) transport system substrate-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] K02018 modB; molybdate transport system permease protein K02020 modA; molybdate transport system substrate-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] K02037 pstC; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein K02040 pstS; phosphate transport system substrate-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] K02042 phnE; phosphonate transport system permease protein K02044 phnD; phosphonate transport system substrate-binding protein K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3] K02046 cysU; sulfate/thiosulfate transport system permease protein K02047 cysW; sulfate/thiosulfate transport system permease protein K02048 cysP; sulfate/thiosulfate transport system substrate-binding protein K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15] K02063 thiP; thiamine transport system permease protein K02064 thiB, tbpA; thiamine transport system substrate-binding protein K02065 mlaF, linL, mkl; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein K02066 mlaE, linK; phospholipid/cholesterol/gamma-HCH transport system permease protein K02067 mlaD, linM; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein K02071 metN; D-methionine transport system ATP-binding protein K02072 metI; D-methionine transport system permease protein K02073 metQ; D-methionine transport system substrate-binding protein K02193 ccmA; heme exporter protein A [EC:7.6.2.5] K02194 ccmB; heme exporter protein B K02195 ccmC; heme exporter protein C K02196 ccmD; heme exporter protein D K02424 tcyA, tcyJ, fliY; L-cystine transport system substrate-binding protein K02471 bacA, bclA; vitamin B12/bleomycin/antimicrobial peptide transport system ATP-binding/permease protein K03523 bioY; biotin transport system substrate-specific component K05031 CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6] K05032 ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8 K05033 ABCC9, SUR2; ATP-binding cassette subfamily C (CFTR/MRP) member 9 K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1 K05642 ABCA2; ATP-binding cassette, subfamily A (ABC1), member 2 K05643 ABCA3; ATP-binding cassette, subfamily A (ABC1), member 3 K05644 ABCA4; ATP-binding cassette, subfamily A (ABC1), member 4 K05645 ABCA7; ATP-binding cassette, subfamily A (ABC1), member 7 K05646 ABCA12; ATP-binding cassette, subfamily A (ABC1), member 12 K05647 ABCA13; ATP binding cassette, subfamily A (ABC1), member 13 K05648 ABCA5; ATP-binding cassette, subfamily A (ABC1), member 5 K05649 ABCA6; ATP-binding cassette, subfamily A (ABC1), member 6 K05650 ABCA8; ATP-binding cassette, subfamily A (ABC1), member 8 K05651 ABCA9; ATP-binding cassette, subfamily A (ABC1), member 9 K05652 ABCA10; ATP-binding cassette, subfamily A (ABC1), member 10 K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14] K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14] K05655 ABCB8; ATP-binding cassette, subfamily B (MDR/TAP), member 8 K05656 ABCB9, TAPL; ATP-binding cassette, subfamily B (MDR/TAP), member 9 K05657 ABCB10; ATP-binding cassette, subfamily B (MDR/TAP), member 10 K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] K05659 ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:7.6.2.2] K05660 ABCB5; ATP-binding cassette, subfamily B (MDR/TAP), member 5 K05661 ABCB6; ATP-binding cassette, subfamily B (MDR/TAP), member 6 K05662 ABCB7, ATM; ATP-binding cassette, subfamily B (MDR/TAP), member 7 K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11 K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2 K05667 ABCC3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3 K05668 ABCC5; ATP-binding cassette, subfamily C (CFTR/MRP), member 5 K05669 ABCC6; ATP-binding cassette, subfamily C (CFTR/MRP), member 6 K05670 ABCC13; ATP-binding cassette, subfamily C (CFTR/MRP), member 13 K05671 ABCC11; ATP-binding cassette, subfamily C (CFTR/MRP), member 11 K05672 ABCC12; ATP-binding cassette, subfamily C (CFTR/MRP), member 12 K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4 K05674 ABCC10; ATP-binding cassette, subfamily C (CFTR/MRP), member 10 K05675 ABCD1, ALD; ATP-binding cassette, subfamily D (ALD), member 1 [EC:7.6.2.4] K05676 ABCD2, ALDL1; ATP-binding cassette, subfamily D (ALD), member 2 [EC:7.6.2.4] K05677 ABCD3, PMP70; ATP-binding cassette, subfamily D (ALD), member 3 [EC:7.6.2.4] K05678 ABCD4, PXMP1L; ATP-binding cassette, subfamily D (ALD), member 4 [EC:7.6.2.8] K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1 K05680 ABCG4; ATP-binding cassette, subfamily G (WHITE), member 4 K05681 ABCG2, CD338; ATP-binding cassette, subfamily G (WHITE), member 2 K05682 ABCG3, Mxr2, Abcp2; ATP-binding cassette, subfamily G (WHITE), member 3 K05683 ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1) K05684 ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2) K05685 macB; macrolide transport system ATP-binding/permease protein [EC:7.6.2.-] K05772 tupA, vupA; tungstate transport system substrate-binding protein K05773 tupB, vupB; tungstate transport system permease protein K05776 modF; molybdate transport system ATP-binding protein K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10] K05845 opuC; osmoprotectant transport system substrate-binding protein K05846 opuBD; osmoprotectant transport system permease protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] K06073 btuC; vitamin B12 transport system permease protein K06074 btuD; vitamin B12 transport system ATP-binding protein [EC:7.6.2.8] K06159 yojI; multidrug/microcin transport system ATP-binding/permease protein K06160 pvdE; putative pyoverdin transport system ATP-binding/permease protein K06161 syrD; putative syringomycin transport system ATP-binding/permease protein K06726 rbsD; D-ribose pyranase [EC:5.4.99.62] K06857 tupC, vupC; tungstate transport system ATP-binding protein [EC:7.3.2.6] K06858 btuF; vitamin B12 transport system substrate-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] K07091 lptF; lipopolysaccharide export system permease protein K07122 mlaB; phospholipid transport system transporter-binding protein K07323 mlaC; phospholipid transport system substrate-binding protein K07335 bmpA, bmpB, tmpC; basic membrane protein A and related proteins K08711 PDR, CDR1; ATP-binding cassette, subfamily G (WHITE), member 2, PDR K08712 SNQ2; ATP-binding cassette, subfamily G (WHITE), member 2, SNQ2 K09688 kpsM; capsular polysaccharide transport system permease protein K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12] K09690 wzm, rfbA; homopolymeric O-antigen transport system permease protein K09691 wzt, rfbB; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] K09692 tagG; teichoic acid transport system permease protein K09693 tagH; teichoic acid transport system ATP-binding protein [EC:7.5.2.4] K09694 nodJ; lipooligosaccharide transport system permease protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein K09696 natB; sodium transport system permease protein K09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4] K09808 lolC_E_F; lipoprotein-releasing system permease protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] K09811 ftsX; cell division transport system permease protein K09812 ftsE; cell division transport system ATP-binding protein K09813 hrtB; hemin transport system permease protein K09814 hrtA; hemin transport system ATP-binding protein [EC:7.6.2.-] K09815 znuA; zinc transport system substrate-binding protein K09816 znuB; zinc transport system permease protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] K09969 aapJ, bztA; general L-amino acid transport system substrate-binding protein K09970 aapQ, bztB; general L-amino acid transport system permease protein K09971 aapM, bztC; general L-amino acid transport system permease protein K09972 aapP, bztD; general L-amino acid transport system ATP-binding protein [EC:7.4.2.1] K09996 artJ; arginine transport system substrate-binding protein K09997 artI; arginine transport system substrate-binding protein K09998 artM; arginine transport system permease protein K09999 artQ; arginine transport system permease protein K10000 artP; arginine transport system ATP-binding protein [EC:7.4.2.1] K10001 gltI, aatJ; glutamate/aspartate transport system substrate-binding protein K10002 gltK, aatM; glutamate/aspartate transport system permease protein K10003 gltJ, aatQ; glutamate/aspartate transport system permease protein K10004 gltL, aatP; glutamate/aspartate transport system ATP-binding protein [EC:7.4.2.1] K10005 gluB; glutamate transport system substrate-binding protein K10006 gluC; glutamate transport system permease protein K10007 gluD; glutamate transport system permease protein K10008 gluA; glutamate transport system ATP-binding protein [EC:7.4.2.1] K10009 tcyB, tcyL; L-cystine transport system permease protein K10010 tcyC, tcyN; L-cystine transport system ATP-binding protein [EC:7.4.2.1] K10013 argT; lysine/arginine/ornithine transport system substrate-binding protein K10014 hisJ; histidine transport system substrate-binding protein K10015 hisM; histidine transport system permease protein K10016 hisQ; histidine transport system permease protein K10017 hisP; histidine transport system ATP-binding protein [EC:7.4.2.1] K10018 occT, nocT; octopine/nopaline transport system substrate-binding protein K10019 occM, nocM; octopine/nopaline transport system permease protein K10020 occQ, nocQ; octopine/nopaline transport system permease protein K10021 occP, nocP; octopine/nopaline transport system ATP-binding protein [EC:7.4.2.1] K10022 aotJ; arginine/ornithine transport system substrate-binding protein K10023 aotM; arginine/ornithine transport system permease protein K10024 aotQ; arginine/ornithine transport system permease protein K10025 aotP; arginine/ornithine transport system ATP-binding protein [EC:7.4.2.1] K10036 glnH; glutamine transport system substrate-binding protein K10037 glnP; glutamine transport system permease protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] K10039 peb1A, glnH; aspartate/glutamate/glutamine transport system substrate-binding protein K10040 peb1B, glnP, glnM; aspartate/glutamate/glutamine transport system permease protein K10041 peb1C, glnQ; aspartate/glutamate/glutamine transport system ATP-binding protein [EC:7.4.2.1] K10094 cbiK; nickel transport protein K10107 kpsE; capsular polysaccharide transport system permease protein K10108 malE; maltose/maltodextrin transport system substrate-binding protein K10109 malF; maltose/maltodextrin transport system permease protein K10110 malG; maltose/maltodextrin transport system permease protein K10111 malK, mtlK, thuK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] K10112 msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein K10118 msmF; raffinose/stachyose/melibiose transport system permease protein K10119 msmG; raffinose/stachyose/melibiose transport system permease protein K10188 lacE, araN; lactose/L-arabinose transport system substrate-binding protein K10189 lacF, araP; lactose/L-arabinose transport system permease protein K10190 lacG, araQ; lactose/L-arabinose transport system permease protein K10191 lacK; lactose/L-arabinose transport system ATP-binding protein K10192 togB; oligogalacturonide transport system substrate-binding protein K10193 togM; oligogalacturonide transport system permease protein K10194 togN; oligogalacturonide transport system permease protein K10195 togA; oligogalacturonide transport system ATP-binding protein K10196 glcS, araS; glucose/arabinose transport system substrate-binding protein K10197 glcT, araT; glucose/arabinose transport system permease protein K10198 glcU, araU; glucose/arabinose transport system permease protein K10199 glcV, araV; glucose/arabinose transport system ATP-binding protein K10200 ngcE; N-acetylglucosamine transport system substrate-binding protein K10201 ngcF; N-acetylglucosamine transport system permease protein K10202 ngcG; N-acetylglucosamine transport system permease protein K10227 smoE, mtlE, mscE; polyol transport system substrate-binding protein K10228 smoF, mtlF, mscF; polyol transport system permease protein K10229 smoG, mtlG, mscG; polyol transport system permease protein K10232 aglE, ggtB; alpha-glucoside transport system substrate-binding protein K10233 aglF, ggtC; alpha-glucoside transport system permease protein K10234 aglG, ggtD; alpha-glucoside transport system permease protein K10235 aglK; alpha-glucoside transport system ATP-binding protein K10236 thuE, lpqY; trehalose/maltose transport system substrate-binding protein K10237 thuF, sugA; trehalose/maltose transport system permease protein K10238 thuG, sugB; trehalose/maltose transport system permease protein K10240 cebE; cellobiose transport system substrate-binding protein K10241 cebF; cellobiose transport system permease protein K10242 cebG; cellobiose transport system permease protein K10439 rbsB; ribose transport system substrate-binding protein K10440 rbsC; ribose transport system permease protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] K10537 araF; L-arabinose transport system substrate-binding protein K10538 araH; L-arabinose transport system permease protein K10539 araG; L-arabinose transport system ATP-binding protein [EC:7.5.2.12] K10540 mglB; methyl-galactoside transport system substrate-binding protein K10541 mglC; methyl-galactoside transport system permease protein K10542 mglA; methyl-galactoside transport system ATP-binding protein [EC:7.5.2.11] K10543 xylF; D-xylose transport system substrate-binding protein K10544 xylH; D-xylose transport system permease protein K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] K10546 chvE; putative multiple sugar transport system substrate-binding protein K10547 gguB; putative multiple sugar transport system permease protein K10548 gguA; putative multiple sugar transport system ATP-binding protein [EC:7.5.2.-] K10549 alsB; D-allose transport system substrate-binding protein K10550 alsC; D-allose transport system permease protein K10551 alsA; D-allose transport system ATP-binding protein [EC:7.5.2.8] K10552 frcB; fructose transport system substrate-binding protein K10553 frcC; fructose transport system permease protein K10554 frcA; fructose transport system ATP-binding protein K10555 lsrB; AI-2 transport system substrate-binding protein K10556 lsrC; AI-2 transport system permease protein K10557 lsrD; AI-2 transport system permease protein K10558 lsrA, ego; AI-2 transport system ATP-binding protein K10559 rhaS; rhamnose transport system substrate-binding protein K10560 rhaP; rhamnose transport system permease protein K10561 rhaQ; rhamnose transport system permease protein K10562 rhaT; rhamnose transport system ATP-binding protein [EC:7.5.2.-] K10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9] K10823 oppF; oligopeptide transport system ATP-binding protein K10824 nikE, cntF; nickel transport system ATP-binding protein [EC:7.2.2.11] K10829 fhuC; ferric hydroxamate transport system ATP-binding protein [EC:7.2.2.16] K10830 psaB, scaC, sloA; manganese/zinc transport system ATP-binding protein [EC:7.2.2.5] K10831 tauB; taurine transport system ATP-binding protein [EC:7.6.2.7] K11004 hlyB, cyaB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB K11050 cylA; multidrug/hemolysin transport system ATP-binding protein K11051 cylB; multidrug/hemolysin transport system permease protein K11069 potD; spermidine/putrescine transport system substrate-binding protein K11070 potC; spermidine/putrescine transport system permease protein K11071 potB; spermidine/putrescine transport system permease protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] K11073 potF, spuD, spuE; putrescine transport system substrate-binding protein K11074 potI, spuH; putrescine transport system permease protein K11075 potH, spuG; putrescine transport system permease protein K11076 potG, spuF; putrescine transport system ATP-binding protein [EC:7.6.2.16] K11077 attC; mannopine transport system substrate-binding protein K11078 attB; mannopine transport system permease protein K11079 attA2; mannopine transport system permease protein K11080 attA1; mannopine transport system ATP-binding protein K11081 phnS; 2-aminoethylphosphonate transport system substrate-binding protein K11082 phnV; 2-aminoethylphosphonate transport system permease protein K11083 phnU; 2-aminoethylphosphonate transport system permease protein K11084 phnT; 2-aminoethylphosphonate transport system ATP-binding protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] K11601 mntC; manganese transport system substrate-binding protein K11602 mntB; manganese transport system permease protein K11603 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5] K11604 sitA; manganese/iron transport system substrate-binding protein K11605 sitC; manganese/iron transport system permease protein K11606 sitD; manganese/iron transport system permease protein K11607 sitB; manganese/iron transport system ATP-binding protein K11631 bceA, vraD; bacitracin transport system ATP-binding protein K11632 bceB, vraE; bacitracin transport system permease protein K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein K11707 troA, mntA, znuA; manganese/zinc/iron transport system substrate-binding protein K11708 troC, mntC, znuB; manganese/zinc/iron transport system permease protein K11709 troD, mntD, znuB; manganese/zinc/iron transport system permease protein K11710 troB, mntB, znuC; manganese/zinc/iron transport system ATP- binding protein [EC:7.2.2.5] K11720 lptG; lipopolysaccharide export system permease protein K11950 cmpA; bicarbonate transport system substrate-binding protein K11951 cmpB; bicarbonate transport system permease protein K11952 cmpC; bicarbonate transport system ATP-binding protein [EC:7.3.2.-] K11953 cmpD; bicarbonate transport system ATP-binding protein [EC:7.3.2.-] K11954 natB; neutral amino acid transport system substrate-binding protein K11955 natC; neutral amino acid transport system permease protein K11956 natD; neutral amino acid transport system permease protein K11957 natA; neutral amino acid transport system ATP-binding protein K11958 natE; neutral amino acid transport system ATP-binding protein K11959 urtA; urea transport system substrate-binding protein K11960 urtB; urea transport system permease protein K11961 urtC; urea transport system permease protein K11962 urtD; urea transport system ATP-binding protein K11963 urtE; urea transport system ATP-binding protein K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] K12368 dppA; dipeptide transport system substrate-binding protein K12369 dppB; dipeptide transport system permease protein K12370 dppC; dipeptide transport system permease protein K12371 dppD; dipeptide transport system ATP-binding protein K12372 dppF; dipeptide transport system ATP-binding protein K12536 hasD, prtD, aprD, rsaD, prsD, eexD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB K13409 cvaB, mchF, raxB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB K13889 gsiB; glutathione transport system substrate-binding protein K13890 gsiC; glutathione transport system permease protein K13891 gsiD; glutathione transport system permease protein K13892 gsiA; glutathione transport system ATP-binding protein K13893 yejA; microcin C transport system substrate-binding protein K13894 yejB; microcin C transport system permease protein K13895 yejE; microcin C transport system permease protein K13896 yejF; microcin C transport system ATP-binding protein K14698 irtA, ybtP; ATP-binding cassette, subfamily B, bacterial IrtA/YbtP [EC:7.-.-.-] K14699 irtB, ybtQ; ATP-binding cassette, subfamily B, bacterial IrtB/YbtQ [EC:7.-.-.-] K15495 wtpA; molybdate/tungstate transport system substrate-binding protein K15496 wtpB; molybdate/tungstate transport system permease protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] K15551 tauA; taurine transport system substrate-binding protein K15552 tauC; taurine transport system permease protein K15553 ssuA; sulfonate transport system substrate-binding protein K15554 ssuC; sulfonate transport system permease protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] K15556 ophF; phthalate transport system substrate-binding protein K15557 ophG; phthalate transport system permease protein K15558 ophH; phthalate transport system ATP-binding protein K15576 nrtA, nasF, cynA; nitrate/nitrite transport system substrate-binding protein K15577 nrtB, nasE, cynB; nitrate/nitrite transport system permease protein K15578 nrtC, nasD; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] K15579 nrtD, cynD; nitrate/nitrite transport system ATP-binding protein K15580 oppA, mppA; oligopeptide transport system substrate-binding protein K15581 oppB; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein K15583 oppD; oligopeptide transport system ATP-binding protein K15584 nikA, cntA; nickel transport system substrate-binding protein K15585 nikB, cntB; nickel transport system permease protein K15586 nikC, cntC; nickel transport system permease protein K15587 nikD, cntD; nickel transport system ATP-binding protein [EC:7.2.2.11] K15598 thiY; putative hydroxymethylpyrimidine transport system substrate-binding protein K15599 thiX; putative hydroxymethylpyrimidine transport system permease protein K15600 thiZ; putative hydroxymethylpyrimidine transport system ATP-binding protein K15628 PXA; ATP-binding cassette, subfamily D (ALD), peroxisomal long-chain fatty acid import protein [EC:7.6.2.4] K15770 cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein K15771 ganP, mdxF; arabinogalactan oligomer / maltooligosaccharide transport system permease protein K15772 ganQ, mdxG; arabinogalactan oligomer / maltooligosaccharide transport system permease protein K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD K16014 cydCD; ATP-binding cassette, subfamily C, bacterial CydCD K16199 dppE; dipeptide transport system substrate-binding protein K16200 dppB1; dipeptide transport system permease protein K16201 dppC; dipeptide transport system permease protein K16202 dppD; dipeptide transport system ATP-binding protein K16783 bioN; biotin transport system permease protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-] K16785 ecfT; energy-coupling factor transport system permease protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] K16905 K16905; fluoroquinolone transport system permease protein K16906 K16906; fluoroquinolone transport system permease protein K16907 K16907; fluoroquinolone transport system ATP-binding protein [EC:7.6.2.-] K16915 cbiL; nickel transport protein K16916 yydJ; putative peptide transport system permease protein K16917 yydI; putative peptide transport system ATP-binding protein K16918 ytrF; acetoin utilization transport system permease protein K16919 ytrC_D; acetoin utilization transport system permease protein K16920 ytrE; acetoin utilization transport system ATP-binding protein K16921 ytrB; acetoin utilization transport system ATP-binding protein K16956 tcyJ; L-cystine transport system substrate-binding protein K16957 tcyK; L-cystine transport system substrate-binding protein K16958 tcyL; L-cystine transport system permease protein K16959 tcyM; L-cystine transport system permease protein K16960 tcyN; L-cystine transport system ATP-binding protein [EC:7.4.2.1] K16961 yxeM; putative S-methylcysteine transport system substrate-binding protein K16962 yxeN; putative S-methylcysteine transport system permease protein K16963 yxeO; putative S-methylcysteine transport system ATP-binding protein K17062 bgtB; arginine/lysine/histidine/glutamine transport system substrate-binding and permease protein K17063 bgtA; arginine/lysine/histidine/glutamine transport system ATP-binding protein [EC:7.4.2.1] K17073 lysX1; putative lysine transport system substrate-binding protein K17074 lysX2; putative lysine transport system permease protein K17076 lysY; putative lysine transport system ATP-binding protein K17077 artQ; arginine/lysine/histidine transport system permease protein K17202 eryG; erythritol transport system substrate-binding protein K17203 eryF; erythritol transport system permease protein K17204 eryE; erythritol transport system ATP-binding protein K17205 xltC; putative xylitol transport system substrate-binding protein K17206 xltB; putative xylitol transport system permease protein K17207 xltA; putative xylitol transport system ATP-binding protein K17208 ibpA; inositol transport system substrate-binding protein K17209 iatP; inositol transport system permease protein K17210 iatA; inositol transport system ATP-binding protein K17213 K17213; inositol transport system substrate-binding protein K17214 K17214; inositol transport system permease protein K17215 K17215; inositol transport system ATP-binding protein K17234 araN; arabinooligosaccharide transport system substrate-binding protein K17235 araP; arabinooligosaccharide transport system permease protein K17236 araQ; arabinooligosaccharide transport system permease protein K17237 inoE; inositol-phosphate transport system substrate-binding protein K17238 inoF; inositol-phosphate transport system permease protein K17239 inoG; inositol-phosphate transport system permease protein K17240 inoK; inositol-phosphate transport system ATP-binding protein K17241 aguE; alpha-1,4-digalacturonate transport system substrate-binding protein K17242 aguF; alpha-1,4-digalacturonate transport system permease protein K17243 aguG; alpha-1,4-digalacturonate transport system permease protein K17244 chiE; putative chitobiose transport system substrate-binding protein K17245 chiF; putative chitobiose transport system permease protein K17246 chiG; putative chitobiose transport system permease protein K17311 treS; trehalose transport system substrate-binding protein K17312 treT; trehalose transport system permease protein K17313 treU; trehalose transport system permease protein K17314 treV; trehalose transport system ATP-binding protein K17315 gtsA, glcE; glucose/mannose transport system substrate-binding protein K17316 gtsB, glcF; glucose/mannose transport system permease protein K17317 gtsC, glcG; glucose/mannose transport system permease protein K17318 lplA; putative aldouronate transport system substrate-binding protein K17319 lplB; putative aldouronate transport system permease protein K17320 lplC; putative aldouronate transport system permease protein K17321 glpV; glycerol transport system substrate-binding protein K17322 glpP; glycerol transport system permease protein K17323 glpQ; glycerol transport system permease protein K17324 glpS; glycerol transport system ATP-binding protein K17325 glpT; glycerol transport system ATP-binding protein K17326 bxlE; xylobiose transport system substrate-binding protein K17327 bxlF; xylobiose transport system permease protein K17328 bxlG; xylobiose transport system permease protein K17329 dasA; N,N'-diacetylchitobiose transport system substrate-binding protein K17330 dasB; N,N'-diacetylchitobiose transport system permease protein K17331 dasC; N,N'-diacetylchitobiose transport system permease protein K18104 abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] K18216 steA, tetA46; ATP-binding cassette, subfamily B, tetracycline resistant protein K18217 steB, tetB46; ATP-binding cassette, subfamily B, tetracycline resistant protein K18230 tylC, oleB, carA, srmB; macrolide transport system ATP-binding/permease protein K18231 msr, vmlR; macrolide transport system ATP-binding/permease protein K18232 oleC4; oleandomycin transport system ATP-binding protein K18233 oleC5; oleandomycin transport system permease protein K18887 efrA, efrE; ATP-binding cassette, subfamily B, multidrug efflux pump K18888 efrB, efrF; ATP-binding cassette, subfamily B, multidrug efflux pump K18889 mdlA, smdA; ATP-binding cassette, subfamily B, multidrug efflux pump K18890 mdlB, smdB; ATP-binding cassette, subfamily B, multidrug efflux pump K18891 patA, rscA, lmrC, satA; ATP-binding cassette, subfamily B, multidrug efflux pump K18892 patB, rscB, lmrC, satB; ATP-binding cassette, subfamily B, multidrug efflux pump K18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump K18894 K18894; ATP-binding cassette, subfamily B, multidrug efflux pump K18895 iroC; ATP-binding cassette, subfamily B, salmochelin/enterobactin exporter K19079 vraF; cationic antimicrobial peptide transport system ATP-binding protein K19080 vraG; cationic antimicrobial peptide transport system permease protein K19083 braD, bceA; bacitracin transport system ATP-binding protein K19084 braE, bceB; bacitracin transport system permease protein K19226 sapA; cationic peptide transport system substrate-binding protein K19227 sapB; cationic peptide transport system permease protein K19228 sapC; cationic peptide transport system permease protein K19229 sapD; cationic peptide transport system ATP-binding protein K19230 sapF; cationic peptide transport system ATP-binding protein K19309 bcrA; bacitracin transport system ATP-binding protein K19310 bcrB; bacitracin transport system permease protein K19340 nosF; Cu-processing system ATP-binding protein K19341 nosY; Cu-processing system permease protein K19349 vga; pleuromutilin/lincosamide/streptogramin A transport system ATP-binding/permease protein K19350 lsa; lincosamide and streptogramin A transport system ATP-binding/permease protein K19971 psaA, scaA, sloC; manganese/zinc transport system substrate-binding protein K19972 psaC, scaB, sloB; manganese/zinc transport system permease protein K19973 mntA; manganese transport system ATP-binding protein [EC:7.2.2.5] K19975 mntC; manganese transport system substrate-binding protein K19976 mntB; manganese transport system permease protein K20344 blpA, lagD; ATP-binding cassette, subfamily C, bacteriocin exporter K20386 cylB; ATP-binding cassette, subfamily B, bacterial CylB K20459 nukF, mcdF, sboF; lantibiotic transport system ATP-binding protein K20460 nukE, mcdE, sboE; lantibiotic transport system permease protein K20461 nukG, mcdG, sboG; lantibiotic transport system permease protein K20490 nisF, spaF, cprA, epiF; lantibiotic transport system ATP-binding protein K20491 nisE, spaE, cprB, epiE; lantibiotic transport system permease protein K20492 nisG, spaG, cprC; lantibiotic transport system permease protein K20494 epiG; lantibiotic transport system permease protein K22921 vexB; Vi polysaccharide transport system permease protein K22922 vexD; Vi polysaccharide transport system permease protein K22923 vexC; Vi polysaccharide transport system ATP-binding protein K23055 K23055; putative lysine/arginine/ornithine/histidine/octopine transport system substrate-binding protein K23056 K23056; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein K23057 K23057; putative lysine/arginine/ornithine/histidine/octopine transport system permease protein K23058 K23058; putative lysine/arginine/ornithine/histidine/octopine transport system ATP-binding protein K23059 artP, artI; arginine/lysine/histidine transporter system substrate-binding protein K23060 artR, artM; arginine/lysine/histidine transport system ATP-binding protein K23061 lhpP; hydroxyproline transporter system substrate-binding protein K23062 lhpM; hydroxyproline transport system permease protein K23063 lhpN; hydroxyproline transport system permease protein K23064 lhpO; hydroxyproline transport system ATP-binding protein K23125 DEFB1; beta-defensin 1 K23163 sbp; sulfate/thiosulfate transport system substrate-binding protein K23181 fecB; ferric citrate transport system substrate-binding protein K23182 fecD; ferric citrate transport system permease protein K23183 fecC; ferric citrate transport system permease protein K23184 fecE; ferric citrate transport system ATP-binding protein K23185 fepB; ferric enterobactin transport system substrate-binding protein K23186 fepD, fagA, cchC, desH; iron-siderophore transport system permease protein K23187 fepG, fagB, cchD, desG; iron-siderophore transport system permease protein K23188 fepC, fagC, cchE, desF; iron-siderophore transport system ATP-binding protein K23227 fhuD; ferric hydroxamate transport system substrate-binding protein K23228 fhuB; ferric hydroxamate transport system permease protein K23508 ytfQ; galactofuranose transport system substrate-binding protein K23509 ytfT, yjfF; galactofuranose transport system permease protein K23510 rfuA; riboflavin transport system substrate-binding protein K23511 rfuC; riboflavin transport system permease protein K23512 rfuD; riboflavin transport system permease protein K23513 rfuB; riboflavin transport system ATP-binding protein K23535 nupB; general nucleoside transport system permease protein K23536 nupC; general nucleoside transport system permease protein K23537 nupA; general nucleoside transport system ATP-binding protein K23545 yphF; sugar transport system substrate-binding protein K23546 yphD; sugar transport system permease protein K23547 yphE; sugar transport system ATP-binding protein K24821 atm1, pexA; ATP-binding cassette, subfamily B, heavy metal transporter K25286 fagD, cchF, irp1A, piaA; iron-siderophore transport system substrate-binding protein K25287 desE; iron-desferrioxamine transport system substrate-binding protein K25819 ABCD1, PXA1; ATP-binding cassette, subfamily D (ALD), peroxisomal ABC transporter COMPOUND C00009 Orthophosphate C00025 L-Glutamate C00031 D-Glucose C00032 Heme C00034 Manganese C00037 Glycine C00038 Zinc cation C00041 L-Alanine C00047 L-Lysine C00049 L-Aspartate C00051 Glutathione C00059 Sulfate C00062 L-Arginine C00064 L-Glutamine C00065 L-Serine C00070 Copper C00077 L-Ornithine C00079 L-Phenylalanine C00086 Urea C00088 Nitrite C00089 Sucrose C00093 sn-Glycerol 3-phosphate C00095 D-Fructose C00098 Oligopeptide C00107 Dipeptide C00114 Choline C00116 Glycerol C00120 Biotin C00121 D-Ribose C00123 L-Leucine C00134 Putrescine C00135 L-Histidine C00137 myo-Inositol C00140 N-Acetyl-D-glucosamine C00148 L-Proline C00151 L-Amino acid C00159 D-Mannose C00175 Cobalt ion C00181 D-Xylose C00183 L-Valine C00185 Cellobiose C00188 L-Threonine C00208 Maltose C00212 Adenosine C00243 Lactose C00244 Nitrate C00245 Taurine C00255 Riboflavin C00259 L-Arabinose C00288 HCO3- C00291 Nickel C00294 Inosine C00299 Uridine C00315 Spermidine C00320 Thiosulfate C00330 Deoxyguanosine C00333 D-Galacturonate C00338 Lipopolysaccharide C00378 Thiamine C00379 Xylitol C00387 Guanosine C00392 Mannitol C00407 L-Isoleucine C00430 5-Aminolevulinate C00470 Pectate C00475 Cytidine C00487 Carnitine C00491 L-Cystine C00492 Raffinose C00503 Erythritol C00526 Deoxyuridine C00559 Deoxyadenosine C00719 Betaine C00794 D-Sorbitol C00855 D-Methionine C00865 Phospholipid C00881 Deoxycytidine C00919 Choline sulfate C00973 Cyclomaltodextrin C01083 alpha,alpha-Trehalose C01153 Orthophosphoric monoester C01157 Hydroxyproline C01177 Inositol 1-phosphate C01181 4-Trimethylammoniobutanoate C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine C01330 Sodium cation C01417 Cyanate C01487 D-Allose C01606 Phthalate C01630 Xylobiose C01667 Bacitracin C01674 Chitobiose C01682 Nopaline C01684 D-Rhamnose C01762 Xanthosine C01834 Lipoprotein C01835 Maltotriose C01935 Maltodextrin C01946 Oleandomycin C02160 Isomaltotriose C02273 Digalacturonate C03557 2-Aminoethylphosphonate C03611 Galactose oligosaccharide C03619 Methyl beta-D-galactoside C04114 (E)-4-(Trimethylammonio)but-2-enoate C04137 Octopine C05349 Ciprofloxacin C05402 Melibiose C05512 Deoxyinosine C05776 Vitamin B12 C06227 Fe(III)hydroxamate C06229 Fe(III)dicitrate C06230 Fe-enterobactin C06232 Molybdate C06687 Norfloxacin C06705 Capsular polysaccharide C06706 Lipo-oligosaccharide C06707 Teichoic acid C06767 Hemine C07662 Sparfloxacin C07663 Moxifloxacin C11612 Polymyxin B C13768 Colistin sulfate C14818 Fe2+ C14819 Fe3+ C15521 Alkanesulfonate C15719 Coelichelin C16421 AI-2 C16692 Mannopine C19609 Nickel(2+) C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine C20570 alpha-1,5-L-Arabinobiose C20571 alpha-1,5-L-Arabinotriose C20572 alpha-1,5-L-Arabinotetraose C20573 Aldotetraouronic acid C20679 Tungstate C21066 D-Galactofuranose C22040 S-Methyl-L-cysteine G00457 Maltotetraose REFERENCE PMID:9799792 AUTHORS Tomii K, Kanehisa M. 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JOURNAL Proc Natl Acad Sci U S A 105:5537-42 (2008) DOI:10.1073/pnas.0801196105 REFERENCE PMID:10557362 AUTHORS Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T TITLE Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942. JOURNAL Proc Natl Acad Sci U S A 96:13571-6 (1999) DOI:10.1073/pnas.96.23.13571 REFERENCE PMID:11731493 AUTHORS Quintero MJ, Montesinos ML, Herrero A, Flores E TITLE Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence. JOURNAL Genome Res 11:2034-40 (2001) DOI:10.1101/gr.196301 REFERENCE PMID:16135226 AUTHORS Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E TITLE ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120. JOURNAL Mol Microbiol 57:1582-92 (2005) DOI:10.1111/j.1365-2958.2005.04791.x REFERENCE PMID:11929526 AUTHORS Valladares A, Montesinos ML, Herrero A, Flores E. TITLE An ABC-type, high-affinity urea permease identified in cyanobacteria. JOURNAL Mol Microbiol 43:703-15 (2002) DOI:10.1046/j.1365-2958.2002.02778.x REFERENCE PMID:18326572 AUTHORS Richard-Fogal CL, Frawley ER, Kranz RG TITLE Topology and function of CcmD in cytochrome c maturation. JOURNAL J Bacteriol 190:3489-93 (2008) DOI:10.1128/JB.00146-08 REFERENCE PMID:16109926 AUTHORS Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H TITLE The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette. JOURNAL J Bacteriol 187:5861-7 (2005) DOI:10.1128/JB.187.17.5861-5867.2005 REFERENCE PMID:17873039 AUTHORS Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K TITLE The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C. JOURNAL J Bacteriol 189:8361-5 (2007) DOI:10.1128/JB.01028-07 REFERENCE PMID:17214741 AUTHORS Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI TITLE Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB. JOURNAL Mol Microbiol 63:895-910 (2007) DOI:10.1111/j.1365-2958.2006.05549.x REFERENCE PMID:18805970 AUTHORS Yamanaka H, Kobayashi H, Takahashi E, Okamoto K TITLE MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II. JOURNAL J Bacteriol 190:7693-8 (2008) DOI:10.1128/JB.00853-08 ///