ENTRY ko01052 Pathway NAME Type I polyketide structures CLASS Metabolism; Metabolism of terpenoids and polyketides PATHWAY_MAP ko01052 Type I polyketide structures ORTHOLOGY K16000 narbonolide/10-deoxymethynolide synthase [EC:2.3.1.240 2.3.1.239] K16001 narbonolide/10-deoxymethynolide synthase [EC:2.3.1.240 2.3.1.239] K16002 narbonolide/10-deoxymethynolide synthase [EC:2.3.1.240 2.3.1.239] K16003 narbonolide synthase [EC:2.3.1.240] K16004 narbonolide/10-deoxymethynolide desosaminyltransferase [EC:2.4.1.277] K16005 narbonolide/10-deoxymethynolide desosaminyltransferase auxiliary protein K16006 pikromycin synthase [EC:1.14.15.33] K10817 6-deoxyerythronolide-B synthase EryAI [EC:2.3.1.94] K24563 6-deoxyerythronolide B synthase EryAII [EC:2.3.1.94] K24564 6-deoxyerythronolide B synthase EryAIII [EC:2.3.1.94] K14366 6-deoxyerythronolide B hydroxylase [EC:1.14.15.35] K14367 erythronolide mycarosyltransferase [EC:2.4.1.328] K14368 3-alpha-mycarosylerythronolide B desosaminyl transferase [EC:2.4.1.278] K15997 3-alpha-mycarosylerythronolide B desosaminyl transferase auxiliary protein K14370 erythromycin 12 hydroxylase [EC:1.14.13.154] K16007 8,8a-deoxyoleandolide synthase 1 K24565 8,8a-deoxyoleandolide synthase 2 K24566 8,8a-deoxyoleandolide synthase 3 K16008 cytochrome P450 monooxygenase OleP K16009 glycosyltransferase OleGII K16010 desosaminyltransferase OleGI K15988 tylactone synthase 1 K24555 tylactone synthase 2 K24556 tylactone synthase 3 K24557 tylactone synthase 4 K24558 tylactone synthase 5 K15989 tylactone mycaminosyltransferase [EC:2.4.1.316] K15990 tylactone mycaminosyltransferase auxiliary protein K15991 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase [EC:1.14.15.34] K15992 cytochrome P450 TylI K15993 O-mycaminosyltylonolide 6-deoxyallosyltransferase [EC:2.4.1.317] K15994 demethyllactenocin mycarosyltransferase [EC:2.4.1.318] K16372 niddamycin polyketide synthase 1 K20786 niddamycin polyketide synthase 2 K16373 niddamycin polyketide synthase 3 K16374 niddamycin polyketide synthase 4/5 K14371 avermectin polyketide synthase AveA1 K24567 avermectin polyketide synthase AveA2 K24568 avermectin polyketide synthase AveA3 K24569 avermectin polyketide synthase AveA4 K14372 cytochrome P450 hydroxylase [EC:1.14.-.-] K14373 C-5 ketoreductase K14374 avermectin B 5-O-methyltransferase [EC:2.1.1.-] K14375 dTDP-L-oleandrosyltransferase [EC:2.4.1.-] K16420 rapamycin polyketide synthase A/B/C K16375 polyketide synthase FkbB K16376 polyketide synthase FkbC K16377 polyketide synthase FkbA K16378 pipecolate-incorporating enzyme K16379 cytochrome P450 C-9 hydroxylase K16380 cytochrome P450 RapN K16381 31-O-methyltransferase K16024 methoxymalonate biosynthesis protein K16025 methoxymalonate biosynthesis acyl carrier protein K16026 methoxymalonate biosynthesis protein K16027 methoxymalonate biosynthesis protein K16028 O-methyltransferase K16029 ansamitocin polyketide synthase A K16030 ansamitocin polyketide synthase B K16031 ansamitocin polyketide synthase C K16032 ansamitocin polyketide synthase D K15466 amide synthase K16033 FADH2-dependent halogenase K16034 20-O-methyltransferase K16035 7-O-carbamoyltransferase [EC:2.1.3.-] K16036 3-O-acyltransferase K16037 4,5-epoxidase K16038 N-methyltransferase [EC:2.1.1.-] K15670 rifamycin polyketide synthase modules 1, 2 and 3 [EC:6.2.1.74] K15671 rifamycin polyketide synthase modules 4, 5 and 6 K15672 rifamycin polyketide synthase modules 7 and 8 K15673 rifamycin polyketide synthase modules 9 and 10 K16022 flavoprotein hydroxylase K16023 acetyltransferase K15467 27-O-demethylrifamycin SV methyltransferase [EC:2.1.1.315] K16382 polyene macrolide polyketide synthase, loading module K16383 polyene macrolide polyketide synthase, A-type KR domains K16384 polyene macrolide polyketide synthase K20787 candicidin polyketide synthase FscC K16385 polyene macrolide polyketide synthase, KS-AT-KR-ACP domains K16386 polyene macrolide polyketide synthase K16387 polyene macrolide polyketide synthase K16388 polyene glycosyltransferase K16389 cytochrome P450 monooxygenase K16390 cytochrome P450 monooxygenase K16391 pimaricinolide synthase, loading module K19203 pimaricinolide synthase PimS1 K19204 pimaricinolide synthase PimS2 K19205 pimaricinolide synthase PimS3 K19206 pimaricinolide synthase PimS4 K16392 candicidin polyketide synthase FscA K16393 candicidin polyketide synthase FscB K19207 candicidin polyketide synthase FscD K19208 candicidin polyketide synthase FscE K25145 candicidin polyketide synthase FscF K16394 epothilone polyketide synthase A K16395 epothilone synthetase B K16396 epothilone polyketide synthase C K16397 epothilone polyketide synthase D K16398 epothilone polyketide synthase E K16399 epothilone polyketide synthase F K16400 cytochrome P450 enzyme K16401 soraphen polyketide synthase A K16402 soraphen polyketide synthase B K16403 O-methyltransferase K16404 reductase K16405 stigmatellin polyketide synthase StiA K16406 stigmatellin polyketide synthase StiB K16407 stigmatellin polyketide synthase StiC K16408 stigmatellin polyketide synthase StiD K16409 stigmatellin polyketide synthase StiE K16410 stigmatellin polyketide synthase StiF K16411 stigmatellin polyketide synthase StiG K16412 stigmatellin polyketide synthase StiH K16413 stigmatellin polyketide synthase StiJ K16414 methyltransferase K16415 cytochrome P450 dependent monooxygenase K16416 myxalamid-type nonribosomal peptide synthetase MxaA K15643 myxalamid-type polyketide synthase MxaB K16417 myxalamid-type polyketide synthase MxaC K15642 myxalamid-type polyketide synthase MxaD K20788 myxalamid-type polyketide synthase MxaE K15641 myxalamid-type polyketide synthase MxaF K16418 mycolactone core lactone polyketide synthase MlsA1 K16450 mycolactone core lactone polyketide synthase MlsA2 K16419 mycolactone side chain polyketide synthase K20789 cytochrome P450 hydroxylase [EC:1.14.-.-] COMPOUND C01375 Tacrolimus C01457 Tylosin C01848 Rifamycin B C01912 Erythromycin C01946 Oleandomycin C06573 Amphotericin B C06690 Candicidin D C07909 Sirolimus C08073 Natamycin C11300 Soraphen A C11984 Avermectin A1a C11996 Methymycin C11999 Pikromycin C12045 Ansamitocin P-3 C12102 Immunomycin C12148 Stigmatellin A C12151 Mycolactone C12152 Niddamycin C12153 Epothilone A C12155 Nystatin A1 C12157 Myxalamid S C21275 Mycolactone C C21276 Mycolactone D C21277 Mycolactone E C21278 Mycolactone F REL_PATHWAY ko00522 Biosynthesis of 12-, 14- and 16-membered macrolides ko01051 Biosynthesis of ansamycins ///