ENTRY ko00970 Pathway NAME Aminoacyl-tRNA biosynthesis CLASS Genetic Information Processing; Translation PATHWAY_MAP ko00970 Aminoacyl-tRNA biosynthesis DRUG D01076 Mupirocin (USP/INN) D02195 Mupirocin calcium (USP) D04413 Halofuginone hydrobromide (USAN) D08034 Halofuginone (INN) D09324 Bederocin (USAN/INN) ORTHOLOGY K14218 tRNA Ala K14219 tRNA Arg K14220 tRNA Asn K14221 tRNA Asp K14222 tRNA Cys K14223 tRNA Gln K14224 tRNA Glu K14225 tRNA Gly K14226 tRNA His K14227 tRNA Ile K14228 tRNA Leu K14229 tRNA Lys K14230 tRNA Met K14231 tRNA Phe K14232 tRNA Pro K14233 tRNA Ser K14234 tRNA Thr K14235 tRNA Trp K14236 tRNA Tyr K14237 tRNA Val K14238 tRNA Sec K14239 tRNA Pyl K01885 glutamyl-tRNA synthetase [EC:6.1.1.17] K14163 bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] K09698 nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] K02433 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] K02434 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] K02435 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] K09482 glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] K03330 glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] K03865 glutamyl-tRNA(Gln) amidotransferase subunit F [EC:6.3.5.7] K01886 glutaminyl-tRNA synthetase [EC:6.1.1.18] K01872 alanyl-tRNA synthetase [EC:6.1.1.7] K22503 aspartyl-tRNA synthetase [EC:6.1.1.12] K01876 aspartyl-tRNA synthetase [EC:6.1.1.12] K24278 ergosteryl-3beta-O-L-aspartate synthase [EC:6.1.1.12 2.3.2.37] K09759 nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] K01893 asparaginyl-tRNA synthetase [EC:6.1.1.22] K01880 glycyl-tRNA synthetase [EC:6.1.1.14] K01878 glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] K01879 glycyl-tRNA synthetase beta chain [EC:6.1.1.14] K14164 glycyl-tRNA synthetase [EC:6.1.1.14] K01868 threonyl-tRNA synthetase [EC:6.1.1.3] K01875 seryl-tRNA synthetase [EC:6.1.1.11] K10837 O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] K03341 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] K01042 L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] K07587 O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] K06868 Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] K01883 cysteinyl-tRNA synthetase [EC:6.1.1.16] K01884 cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16] K01874 methionyl-tRNA synthetase [EC:6.1.1.10] K00604 methionyl-tRNA formyltransferase [EC:2.1.2.9] K01873 valyl-tRNA synthetase [EC:6.1.1.9] K01869 leucyl-tRNA synthetase [EC:6.1.1.4] K01870 isoleucyl-tRNA synthetase [EC:6.1.1.5] K04567 lysyl-tRNA synthetase, class II [EC:6.1.1.6] K04566 lysyl-tRNA synthetase, class I [EC:6.1.1.6] K11627 pyrrolysyl-tRNA synthetase [EC:6.1.1.26] K01887 arginyl-tRNA synthetase [EC:6.1.1.19] K01881 prolyl-tRNA synthetase [EC:6.1.1.15] K01892 histidyl-tRNA synthetase [EC:6.1.1.21] K01889 phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] K01890 phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] K01866 tyrosyl-tRNA synthetase [EC:6.1.1.1] K01867 tryptophanyl-tRNA synthetase [EC:6.1.1.2] COMPOUND C00025 L-Glutamate C00037 Glycine C00041 L-Alanine C00047 L-Lysine C00049 L-Aspartate C00062 L-Arginine C00064 L-Glutamine C00065 L-Serine C00073 L-Methionine C00078 L-Tryptophan C00079 L-Phenylalanine C00082 L-Tyrosine C00097 L-Cysteine C00101 Tetrahydrofolate C00123 L-Leucine C00135 L-Histidine C00148 L-Proline C00152 L-Asparagine C00183 L-Valine C00188 L-Threonine C00234 10-Formyltetrahydrofolate C00407 L-Isoleucine C00886 L-Alanyl-tRNA C01005 O-Phospho-L-serine C01931 L-Lysyl-tRNA C02047 L-Leucyl-tRNA C02163 L-Arginyl-tRNA(Arg) C02282 Glutaminyl-tRNA C02412 Glycyl-tRNA(Gly) C02430 L-Methionyl-tRNA C02553 L-Seryl-tRNA(Ser) C02554 L-Valyl-tRNA(Val) C02702 L-Prolyl-tRNA(Pro) C02839 L-Tyrosyl-tRNA(Tyr) C02984 L-Aspartyl-tRNA(Asp) C02987 L-Glutamyl-tRNA(Glu) C02988 L-Histidyl-tRNA(His) C02992 L-Threonyl-tRNA(Thr) C03125 L-Cysteinyl-tRNA(Cys) C03127 L-Isoleucyl-tRNA(Ile) C03294 N-Formylmethionyl-tRNA C03402 L-Asparaginyl-tRNA(Asn) C03511 L-Phenylalanyl-tRNA(Phe) C03512 L-Tryptophanyl-tRNA(Trp) C06112 L-Glutamyl-tRNA(Gln) C06113 L-Aspartyl-tRNA(Asn) C06481 L-Seryl-tRNA(Sec) C06482 L-Selenocysteinyl-tRNA(Sec) C16138 L-Pyrrolysine C16638 O-Phosphoseryl-tRNA(Sec) C17022 O-Phosphoseryl-tRNA(Cys) C17027 L-Pyrrolysyl-tRNA(Pyl) REFERENCE PMID:18252769 AUTHORS Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D TITLE From one amino acid to another: tRNA-dependent amino acid biosynthesis. JOURNAL Nucleic Acids Res 36:1813-25 (2008) DOI:10.1093/nar/gkn015 REFERENCE PMID:15314242 AUTHORS Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D TITLE An aminoacyl-tRNA synthetase that specifically activates pyrrolysine. JOURNAL Proc Natl Acad Sci U S A 101:12450-4 (2004) DOI:10.1073/pnas.0405362101 REL_PATHWAY ko00250 Alanine, aspartate and glutamate metabolism ko00260 Glycine, serine and threonine metabolism ko00270 Cysteine and methionine metabolism ko00290 Valine, leucine and isoleucine biosynthesis ko00300 Lysine biosynthesis ko00330 Arginine and proline metabolism ko00340 Histidine metabolism ko00380 Tryptophan metabolism ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis ///