ENTRY ko00970 Pathway NAME Aminoacyl-tRNA biosynthesis CLASS Genetic Information Processing; Translation PATHWAY_MAP ko00970 Aminoacyl-tRNA biosynthesis DRUG D01076 Mupirocin (USP/INN) D02195 Mupirocin calcium (USP) D04413 Halofuginone hydrobromide (USAN) D08034 Halofuginone (INN) D09324 Bederocin (USAN/INN) ORTHOLOGY K00604 MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9] K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] K01866 YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1] K01867 WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] K01868 TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] K01869 LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4] K01870 IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] K01872 AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] K01873 VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9] K01874 MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10] K01875 SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] K01876 DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12] K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] K01880 GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14] K01881 PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15] K01883 CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16] K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16] K01885 EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17] K01886 QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18] K01887 RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19] K01889 FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] K01890 FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] K01892 HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21] K01893 NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22] K02433 gatA, QRSL1; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] K02434 gatB, PET112; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] K03865 GTF1; glutamyl-tRNA(Gln) amidotransferase subunit F K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] K04567 KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] K09759 aspC, aspS; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26] K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] K14164 glyQS; glycyl-tRNA synthetase [EC:6.1.1.14] K14218 tRNA-Ala; tRNA Ala K14219 tRNA-Arg; tRNA Arg K14220 tRNA-Asn; tRNA Asn K14221 tRNA-Asp; tRNA Asp K14222 tRNA-Cys; tRNA Cys K14223 tRNA-Gln; tRNA Gln K14224 tRNA-Glu; tRNA Glu K14225 tRNA-Gly; tRNA Gly K14226 tRNA-His; tRNA His K14227 tRNA-Ile; tRNA Ile K14228 tRNA-Leu; tRNA Leu K14229 tRNA-Lys; tRNA Lys K14230 tRNA-Met; tRNA Met K14231 tRNA-Phe; tRNA Phe K14232 tRNA-Pro; tRNA Pro K14233 tRNA-Ser; tRNA Ser K14234 tRNA-Thr; tRNA Thr K14235 tRNA-Trp; tRNA Trp K14236 tRNA-Tyr; tRNA Tyr K14237 tRNA-Val; tRNA Val K14238 tRNA-Sec; tRNA Sec K14239 tRNA-Pyl; tRNA Pyl K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12] K24278 ERDS; ergosteryl-3beta-O-L-aspartate synthase COMPOUND C00025 L-Glutamate C00037 Glycine C00041 L-Alanine C00047 L-Lysine C00049 L-Aspartate C00062 L-Arginine C00064 L-Glutamine C00065 L-Serine C00073 L-Methionine C00078 L-Tryptophan C00079 L-Phenylalanine C00082 L-Tyrosine C00097 L-Cysteine C00101 Tetrahydrofolate C00123 L-Leucine C00135 L-Histidine C00148 L-Proline C00152 L-Asparagine C00183 L-Valine C00188 L-Threonine C00234 10-Formyltetrahydrofolate C00407 L-Isoleucine C00886 L-Alanyl-tRNA C01005 O-Phospho-L-serine C01931 L-Lysyl-tRNA C02047 L-Leucyl-tRNA C02163 L-Arginyl-tRNA(Arg) C02282 Glutaminyl-tRNA C02412 Glycyl-tRNA(Gly) C02430 L-Methionyl-tRNA C02553 L-Seryl-tRNA(Ser) C02554 L-Valyl-tRNA(Val) C02702 L-Prolyl-tRNA(Pro) C02839 L-Tyrosyl-tRNA(Tyr) C02984 L-Aspartyl-tRNA(Asp) C02987 L-Glutamyl-tRNA(Glu) C02988 L-Histidyl-tRNA(His) C02992 L-Threonyl-tRNA(Thr) C03125 L-Cysteinyl-tRNA(Cys) C03127 L-Isoleucyl-tRNA(Ile) C03294 N-Formylmethionyl-tRNA C03402 L-Asparaginyl-tRNA(Asn) C03511 L-Phenylalanyl-tRNA(Phe) C03512 L-Tryptophanyl-tRNA(Trp) C06112 L-Glutamyl-tRNA(Gln) C06113 L-Aspartyl-tRNA(Asn) C06481 L-Seryl-tRNA(Sec) C06482 L-Selenocysteinyl-tRNA(Sec) C16138 L-Pyrrolysine C16638 O-Phosphoseryl-tRNA(Sec) C17022 O-Phosphoseryl-tRNA(Cys) C17027 L-Pyrrolysyl-tRNA(Pyl) REFERENCE PMID:18252769 AUTHORS Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D TITLE From one amino acid to another: tRNA-dependent amino acid biosynthesis. JOURNAL Nucleic Acids Res 36:1813-25 (2008) DOI:10.1093/nar/gkn015 REFERENCE PMID:15314242 AUTHORS Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D TITLE An aminoacyl-tRNA synthetase that specifically activates pyrrolysine. JOURNAL Proc Natl Acad Sci U S A 101:12450-4 (2004) DOI:10.1073/pnas.0405362101 REL_PATHWAY ko00250 Alanine, aspartate and glutamate metabolism ko00260 Glycine, serine and threonine metabolism ko00270 Cysteine and methionine metabolism ko00290 Valine, leucine and isoleucine biosynthesis ko00300 Lysine biosynthesis ko00330 Arginine and proline metabolism ko00340 Histidine metabolism ko00380 Tryptophan metabolism ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis ///