ENTRY       ko00903                     Pathway
NAME        Limonene degradation
CLASS       Metabolism; Metabolism of terpenoids and polyketides
PATHWAY_MAP ko00903  Limonene degradation
DBLINKS     GO: 0046251
ORTHOLOGY   K07382  (S)-limonene 7-monooxygenase [EC:1.14.14.52]
            K14732  limonene hydroxylase [EC:1.14.14.51 1.14.14.52 1.1.1.243 1.1.1.144]
            K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
            K14733  limonene 1,2-monooxygenase [EC:1.14.13.107]
            K10533  limonene-1,2-epoxide hydrolase [EC:3.3.2.8]
            K07381  (S)-limonene 6-monooxygenase [EC:1.14.14.51]
            K14730  (-)-trans-carveol dehydrogenase [EC:1.1.1.243]
            K14731  epsilon-lactone hydrolase [EC:3.1.1.83]
            K12466  (+)-trans-carveol dehydrogenase [EC:1.1.1.275]
COMPOUND    C00521  (S)-Limonene
            C00964  (-)-trans-Carveol
            C01767  (-)-Carvone
            C02452  (-)-Perillyl alcohol
            C02576  Perillyl aldehyde
            C06099  (R)-Limonene
            C07271  Limonene-1,2-epoxide
            C07276  Limonene-1,2-diol
            C11383  (+)-(S)-Carvone
            C11395  (4R,6R)-cis-Carveol
            C11396  (1R,2R,4R)-Dihydrocarveol
            C11397  (1R,2S,4R)-Neo-dihydrocarveol
            C11398  (1R,4R)-Dihydrocarvone
            C11399  (1S,2S,4R)-Iso-dihydrocarveol
            C11400  (1S,2R,4R)-Neoiso-dihydrocarveol
            C11401  (1S,4R)-Iso-dihydrocarvone
            C11402  (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
            C11403  (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone
            C11404  (3R)-6-Hydroxy-3-isopropenyl-heptanoate
            C11405  (3R)-3-Isopropenyl-6-oxoheptanoate
            C11406  (5R)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
            C11407  (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA
            C11408  (4S,6S)-cis-Carveol
            C11409  (+)-trans-Carveol
            C11410  (1R,2S,4S)-Neoiso-dihydrocarveol
            C11411  (1R,2R,4S)-Iso-dihydrocarveol
            C11412  (1R,4S)-Iso-dihydrocarvone
            C11413  (1S,2S,4S)-Dihydrocarveol
            C11414  (4S,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
            C11415  (1S,4S)-Dihydrocarvone
            C11416  (1S,2R,4S)-Neo-dihydrocarveol
            C11417  (3S)-6-Hydroxy-3-isopropenyl-heptanoate
            C11418  (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone
            C11419  (3S)-3-Isopropenyl-6-oxoheptanoate
            C11420  (5S)-6-Hydroxy-5-isopropenyl-2-methylhexanoate
            C11421  (3S)-3-Isopropenyl-6-oxoheptanoyl-CoA
            C11924  Perillic acid
            C11929  Perillyl-CoA
            C11934  2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA
            C11935  4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA
            C11936  3-Isopropenylpimelyl-CoA
            C11937  (1S,4R)-1-Hydroxy-2-oxolimonene
            C19079  (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone
            C19081  (4S)-Limonene-1,2-epoxide
            C19082  (1R,2R,4S)-Limonene-1,2-diol
            C19083  (1R,4S)-1-Hydroxy-2-oxolimonene
            C19084  (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone
REFERENCE   PMID:10224006
  AUTHORS   van der Werf MJ, Swarts HJ, de Bont JA
  TITLE     Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
  JOURNAL   Appl Environ Microbiol 65:2092-102 (1999)
            DOI:10.1128/AEM.65.5.2092-2102.1999
REFERENCE   PMID:10832640
  AUTHORS   van der Werf MJ, Boot AM
  TITLE     Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14.
  JOURNAL   Microbiology 146 ( Pt 5):1129-41 (2000)
            DOI:10.1099/00221287-146-5-1129
REL_PATHWAY ko00902  Monoterpenoid biosynthesis
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