ENTRY ko00650 Pathway NAME Butanoate metabolism CLASS Metabolism; Carbohydrate metabolism PATHWAY_MAP ko00650 Butanoate metabolism MODULE M00027 GABA (gamma-Aminobutyrate) shunt [PATH:ko00650] M00088 Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH:ko00650] DBLINKS GO: 0019605 ORTHOLOGY K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] K00022 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] K07516 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] K01825 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] K01782 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] K01692 enoyl-CoA hydratase [EC:4.2.1.17] K01715 enoyl-CoA hydratase [EC:4.2.1.17] K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] K07514 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] K07511 enoyl-CoA hydratase [EC:4.2.1.17] K00248 butyryl-CoA dehydrogenase [EC:1.3.8.1] K00209 enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] K17829 crotonyl-CoA reductase [EC:1.3.1.86] K01034 acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] K01035 acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] K19709 acetate CoA-transferase [EC:2.8.3.8] K23756 medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2] K01896 medium-chain acyl-CoA synthetase [EC:6.2.1.2] K01913 acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2] K00929 butyrate kinase [EC:2.7.2.7] K00634 phosphate butyryltransferase [EC:2.3.1.19] K00132 acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10] K04072 acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] K04073 acetaldehyde dehydrogenase [EC:1.2.1.10] K18366 acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87] K00100 butanol dehydrogenase [EC:1.1.1.-] K21317 butane monooxygenase alpha subunit [EC:1.14.13.230] K21318 butane monooxygenase beta subunit [EC:1.14.13.230] K21319 butane monooxygenase gamma subunit [EC:1.14.13.230] K21320 butane monooxygenase reductase K21321 butane monooxygenase regulatory protein K21322 butane monooxygenase hypothetical assembly protein K17865 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55] K03821 poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] K22881 poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE K05973 poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75] K00023 acetoacetyl-CoA reductase [EC:1.1.1.36] K01615 glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] K20509 carboxybiotin decarboxylase [EC:7.2.4.1] K23351 glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma K23352 glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit delta K01039 glutaconate CoA-transferase, subunit A [EC:2.8.3.12] K01040 glutaconate CoA-transferase, subunit B [EC:2.8.3.12] K00109 2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] K07246 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] K01799 maleate isomerase [EC:5.2.1.1] K00239 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] K00240 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] K00241 succinate dehydrogenase cytochrome b subunit K00242 succinate dehydrogenase membrane anchor subunit K18859 succinate dehydrogenase subunit D K18860 succinate dehydrogenase subunit D K00244 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] K00245 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] K00246 succinate dehydrogenase subunit C K00247 succinate dehydrogenase subunit D K00233 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12] K25995 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12] K25996 succinate dehydrogenase subunit C K26318 fumarate reductase (cytochrome) [EC:1.3.2.4] K01580 glutamate decarboxylase [EC:4.1.1.15] K00823 4-aminobutyrate aminotransferase [EC:2.6.1.19] K14268 5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19] K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] K13524 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] K16871 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96] K00135 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] K00139 succinate-semialdehyde dehydrogenase [EC:1.2.1.24] K17761 succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24] K08324 succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24] K18118 succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] K18119 succinate-semialdehyde dehydrogenase [EC:1.2.1.76] K18120 4-hydroxybutyrate dehydrogenase [EC:1.1.1.61] K00043 4-hydroxybutyrate dehydrogenase [EC:1.1.1.61] K08318 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase [EC:1.1.1.61 1.1.1.373] K18121 glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-] K18122 4-hydroxybutyrate CoA-transferase [EC:2.8.3.-] K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] K00656 formate C-acetyltransferase [EC:2.3.1.54] K00169 pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] K00170 pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] K00172 pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] K00189 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] K00171 pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] K03737 pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] K00174 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] K00175 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] K01641 hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] K01027 3-oxoacid CoA-transferase [EC:2.8.3.5] K01028 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] K01029 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] K01907 acetoacetyl-CoA synthetase [EC:6.2.1.16] K00019 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] K07518 hydroxybutyrate-dimer hydrolase [EC:3.1.1.22] K01574 acetoacetate decarboxylase [EC:4.1.1.4] K18223 propane 2-monooxygenase large subunit [EC:1.14.13.227] K18224 propane 2-monooxygenase small subunit [EC:1.14.13.227] K18226 propane monooxygenase coupling protein K18225 propane monooxygenase reductase component [EC:1.18.1.-] K23259 isopropanol dehydrogenase (NADP+) [EC:1.1.1.80] K18382 NAD+-dependent secondary alcohol dehydrogenase Adh1 [EC:1.1.1.-] K18369 alcohol dehydrogenase [EC:1.1.1.-] K18370 alcohol dehydrogenase [EC:1.1.1.-] K18371 acetone monooxygenase (methyl acetate-forming) [EC:1.14.13.226] K18372 methyl acetate hydrolase [EC:3.1.1.114] K01652 acetolactate synthase I/II/III large subunit [EC:2.2.1.6] K01653 acetolactate synthase I/III small subunit [EC:2.2.1.6] K11258 acetolactate synthase II small subunit [EC:2.2.1.6] K01575 acetolactate decarboxylase [EC:4.1.1.5] K00004 (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303] K03366 meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] K18009 meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] COMPOUND C00022 Pyruvate C00024 Acetyl-CoA C00025 L-Glutamate C00026 2-Oxoglutarate C00042 Succinate C00091 Succinyl-CoA C00122 Fumarate C00132 Methanol C00136 Butanoyl-CoA C00164 Acetoacetate C00207 Acetone C00232 Succinate semialdehyde C00246 Butanoic acid C00332 Acetoacetyl-CoA C00334 4-Aminobutanoate C00356 (S)-3-Hydroxy-3-methylglutaryl-CoA C00497 (R)-Malate C00741 Diacetyl C00810 (R)-Acetoin C00877 Crotonoyl-CoA C00989 4-Hydroxybutanoic acid C01089 (R)-3-Hydroxybutanoate C01144 (S)-3-Hydroxybutanoyl-CoA C01384 Maleic acid C01412 Butanal C01769 (S)-Acetoin C01845 Propan-2-ol C02331 Vinylacetyl-CoA C02411 Glutaconyl-1-CoA C02527 Butanoylphosphate C02630 2-Hydroxyglutarate C03044 (R,R)-Butane-2,3-diol C03046 (S,S)-Butane-2,3-diol C03058 2-Hydroxyglutaryl-CoA C03561 (R)-3-Hydroxybutanoyl-CoA C04546 (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate C06010 (S)-2-Acetolactate C06142 1-Butanol C06143 Poly-beta-hydroxybutyrate C06144 3-Butynoate C06145 3-Butyn-1-al C06146 3-Butyn-1-ol C11062 4-Hydroxybutyryl-CoA C17530 Methyl acetate C20657 meso-2,3-Butanediol C20783 Propane C21390 Butane REL_PATHWAY ko00010 Glycolysis / Gluconeogenesis ko00020 Citrate cycle (TCA cycle) ko00250 Alanine, aspartate and glutamate metabolism ko00330 Arginine and proline metabolism ko00620 Pyruvate metabolism ko00750 Vitamin B6 metabolism ko01056 Biosynthesis of type II polyketide backbone ///