ENTRY ko00640 Pathway NAME Propanoate metabolism CLASS Metabolism; Carbohydrate metabolism PATHWAY_MAP ko00640 Propanoate metabolism MODULE M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH:ko00640] M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ko00640] M00982 Methylcitrate cycle [PATH:ko00640] DBLINKS GO: 0019541 ORTHOLOGY K01895 acetyl-CoA synthetase [EC:6.2.1.1] K01908 propionyl-CoA synthetase [EC:6.2.1.17] K01026 propionate CoA-transferase [EC:2.8.3.1] K01905 acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] K22224 acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] K24012 acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] K00925 acetate kinase [EC:2.7.2.1] K00932 propionate kinase [EC:2.7.2.15] K19697 propionate kinase [EC:2.7.2.15] K26355 acrylate reductase [EC:1.3.1.125] K00625 phosphate acetyltransferase [EC:2.3.1.8] K13788 phosphate acetyltransferase [EC:2.3.1.8] K15024 putative phosphotransacetylase [EC:2.3.1.8] K13923 phosphate propanoyltransferase [EC:2.3.1.222] K00166 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] K00167 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] K11381 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] K09699 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] K00382 dihydrolipoyl dehydrogenase [EC:1.8.1.4] K00169 pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] K00170 pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] K00172 pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] K00189 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] K00171 pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] K00656 formate C-acetyltransferase [EC:2.3.1.54] K00248 butyryl-CoA dehydrogenase [EC:1.3.8.1] K00232 acyl-CoA oxidase [EC:1.3.3.6] K19745 acrylyl-CoA reductase (NADPH) [EC:1.3.1.-] K20143 acrylyl-CoA reductase (NADH) [EC:1.3.1.95] K20626 lactoyl-CoA dehydratase subunit alpha [EC:4.2.1.54] K20627 lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54] K01692 enoyl-CoA hydratase [EC:4.2.1.17] K01825 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] K01782 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] K07514 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] K07511 enoyl-CoA hydratase [EC:4.2.1.17] K14729 multifunctional beta-oxidation protein [EC:4.2.1.- 1.1.1.-] K05605 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] K23146 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase [EC:1.1.1.31 1.1.1.59] K11262 acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K01946 acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K01962 acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] K02160 acetyl-CoA carboxylase biotin carboxyl carrier protein K01961 acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] K01963 acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] K11263 acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14] K18472 acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] K19312 acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] K22568 acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3] K01964 acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] K15036 acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] K15037 biotin carboxyl carrier protein K01578 malonyl-CoA decarboxylase [EC:4.1.1.9] K03416 methylmalonyl-CoA carboxyltransferase 5S subunit [EC:2.1.3.1] K17489 methylmalonyl-CoA carboxyltransferase 12S subunit [EC:2.1.3.1] K17490 methylmalonyl-CoA carboxyltransferase 1.3S subunit [EC:2.1.3.1] K14468 malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.2.1.75 1.1.1.298] K00823 4-aminobutyrate aminotransferase [EC:2.6.1.19] K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] K13524 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] K00822 beta-alanine--pyruvate transaminase [EC:2.6.1.18] K25571 beta-alanine---2-oxoglutarate transaminase [EC:2.6.1.120] K01965 propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3] K01966 propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15] K27094 propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.3 6.4.1.- 2.1.3.15] K27095 acyl-CoA carboxylase epsilon subunit K18426 ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.-] K11264 methylmalonyl-CoA decarboxylase [EC:4.1.1.-] K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] K01849 methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] K01848 methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] K22214 propionyl-CoA:succinyl-CoA transferase [EC:2.8.3.27] K01899 succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] K01900 succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] K01903 succinyl-CoA synthetase beta subunit [EC:6.2.1.5] K01902 succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] K00140 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] K01659 2-methylcitrate synthase [EC:2.3.3.5] K27797 2-methylcitrate synthase [EC:2.3.3.5] K01720 2-methylcitrate dehydratase [EC:4.2.1.79] K20455 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) [EC:4.2.1.117] K09788 2-methylaconitate isomerase [EC:5.3.3.-] K27802 aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] K01682 aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] K03417 methylisocitrate lyase [EC:4.1.3.30] K01637 isocitrate/methylisocitrate lyase [EC:4.1.3.1 4.1.3.30] K00016 L-lactate dehydrogenase [EC:1.1.1.27] K01734 methylglyoxal synthase [EC:4.2.3.3] K08325 NADP-dependent alcohol dehydrogenase [EC:1.1.-.-] K18471 methylglyoxal reductase [EC:1.1.1.-] K00005 glycerol dehydrogenase [EC:1.1.1.6] K17741 NADPH-dependent methylglyoxal reductase [EC:1.1.1.283] K23257 methylglyoxal/glyoxal reductase [EC:1.1.1.283 1.1.1.-] K00048 lactaldehyde reductase [EC:1.1.1.77] K01699 propanediol dehydratase large subunit [EC:4.2.1.28] K13919 propanediol dehydratase medium subunit [EC:4.2.1.28] K13920 propanediol dehydratase small subunit [EC:4.2.1.28] K00086 1,3-propanediol dehydrogenase [EC:1.1.1.202] K13921 1-propanol dehydrogenase K13922 propionaldehyde dehydrogenase [EC:1.2.1.87] COMPOUND C00024 Acetyl-CoA C00036 Oxaloacetate C00042 Succinate C00068 Thiamin diphosphate C00083 Malonyl-CoA C00091 Succinyl-CoA C00099 beta-Alanine C00100 Propanoyl-CoA C00109 2-Oxobutanoate C00111 Glycerone phosphate C00163 Propanoate C00186 (S)-Lactate C00222 3-Oxopropanoate C00424 (S)-Lactaldehyde C00479 Propanal C00511 Acrylic acid C00546 Methylglyoxal C00583 Propane-1,2-diol C00683 (S)-Methylmalonyl-CoA C00804 Propynoate C00827 Lactoyl-CoA C00894 Propenoyl-CoA C01013 3-Hydroxypropanoate C01213 (R)-Methylmalonyl-CoA C02170 Methylmalonate C02225 2-Methylcitrate C02335 beta-Alanyl-CoA C02876 Propanoyl phosphate C04225 (Z)-But-2-ene-1,2,3-tricarboxylate C04593 (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate C05235 Hydroxyacetone C05668 3-Hydroxypropionyl-CoA C05979 Propane-1-ol C05983 Propionyladenylate C05984 2-Hydroxybutanoic acid C05989 3-Oxopropionyl-CoA C06002 (S)-Methylmalonate semialdehyde C15972 Enzyme N6-(lipoyl)lysine C15973 Enzyme N6-(dihydrolipoyl)lysine C21017 2-(alpha-Hydroxypropyl)thiamine diphosphate C21018 Enzyme N6-(S-propyldihydrolipoyl)lysine C21250 2-Methyl-trans-aconitate REL_PATHWAY ko00010 Glycolysis / Gluconeogenesis ko00020 Citrate cycle (TCA cycle) ko00260 Glycine, serine and threonine metabolism ko00270 Cysteine and methionine metabolism ko00280 Valine, leucine and isoleucine degradation ko00410 beta-Alanine metabolism ko00620 Pyruvate metabolism ko00660 C5-Branched dibasic acid metabolism ko00770 Pantothenate and CoA biosynthesis ///