ENTRY ko00625 Pathway NAME Chloroalkane and chloroalkene degradation CLASS Metabolism; Xenobiotics biodegradation and metabolism PATHWAY_MAP ko00625 Chloroalkane and chloroalkene degradation DBLINKS UMBBD: tce tce2 tca atl dcm dce cpr caa ORTHOLOGY K00114 exaA; alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8] K00121 frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] K00148 fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46] K00531 anfG; nitrogenase delta subunit [EC:1.18.6.1] K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] K01561 dehH; haloacetate dehalogenase [EC:3.8.1.3] K01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5] K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] K02588 nifH; nitrogenase iron protein NifH K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] K03268 todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha [EC:1.14.12.3 1.14.12.11 1.14.12.26] K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76] K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] K13954 yiaY; alcohol dehydrogenase [EC:1.1.1.1] K14028 mdh1, mxaF; methanol dehydrogenase (cytochrome c) subunit 1 [EC:1.1.2.7] K14029 mdh2, mxaI; methanol dehydrogenase (cytochrome c) subunit 2 [EC:1.1.2.7] K14419 caaD1; alpha-subunit of trans-3-chloroacrylic acid dehalogenase [EC:3.8.1.-] K14420 caaD2; beta-subunit of trans-3-chloroacrylic acid dehalogenase [EC:3.8.1.-] K14421 cis-caaD; cis-3-chloroacrylic acid dehalogenase [EC:3.8.1.-] K14422 msaD; malonate semialdehyde decarboxylase [EC:4.1.1.-] K16268 todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta [EC:1.14.12.3 1.14.12.11 1.14.12.26] K17067 mdo; formaldehyde dismutase / methanol dehydrogenase [EC:1.2.98.1 1.1.99.37] K17068 fdm; formaldehyde dismutase [EC:1.2.98.1] K17070 dcmA; dichloromethane dehalogenase [EC:4.5.1.3] K18089 todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component K18090 todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component [EC:1.18.1.3 1.18.1.-] K20625 ahy; acetylene hydratase [EC:4.2.1.112] K21647 pceA; tetrachloroethene reductive dehalogenase [EC:1.21.99.5] K21648 pceB; tetrachloroethene reductive dehalogenase membrane anchor K22353 etnC; alkene monooxygenase alpha subunit [EC:1.14.13.69] K22354 etnA; alkene monooxygenase beta subunit [EC:1.14.13.69] K22355 etnB; alkene monooxygenase coupling protein K22356 etnD; alkene monooxygenase reductase K22357 amoA; alkene monooxygenase alpha subunit [EC:1.14.13.69] K22358 amoE; alkene monooxygenase beta subunit [EC:1.14.13.69] K22359 amoB; alkene monooxygenase gamma subunit [EC:1.14.13.69] K22360 amoC; alkene monooxygenase ferredoxin subunit K22361 amoD; alkene monooxygenase effector subunit K22362 amoF; alkene monooxygenase ferredoxin reductase component [EC:1.18.1.3] K22363 etnE; 2-hydroxypropyl-CoM lyase [EC:4.4.1.23] COMPOUND C00011 CO2 C00024 Acetyl-CoA C00048 Glyoxylate C00058 Formate C00067 Formaldehyde C00084 Acetaldehyde C00160 Glycolate C00209 Oxalate C00222 3-Oxopropanoate C00237 CO C01380 Ethylene glycol C01548 Acetylene C02271 Dichloromethane C06547 Ethylene C06548 Ethylene oxide C06609 trans-1,3-Dichloropropene C06610 cis-1,3-Dichloropropene C06611 trans-3-Chloro-2-propene-1-ol C06612 cis-3-Chloro-2-propene-1-ol C06613 trans-3-Chloroallyl aldehyde C06614 trans-3-Chloroacrylic acid C06615 cis-3-Chloroacrylic acid C06752 1,2-Dichloroethane C06753 2-Chloroethanol C06754 Chloroacetaldehyde C06755 Chloroacetic acid C06789 Tetrachloroethene C06790 Trichloroethene C06791 trans-1,2-Dichloroethene C06792 cis-1,2-Dichloroethene C06793 Vinyl chloride C07490 Trichloroethanol C11148 TCE epoxide C11149 Dichloroacetate C11150 Trichloroacetate C14866 Chloral C16348 cis-3-Chloroallyl aldehyde C18246 1,1,1-Trichloroethane C18247 1,1-Dichloroethane C18248 Chloroethane C20303 Chloroethylene oxide C21752 2-Hydroxyethyl-CoM C21753 2-Chloro-2-hydroxyethyl-CoM REFERENCE PMID:15294827 AUTHORS Muller JA, Rosner BM, Von Abendroth G, Meshulam-Simon G, McCarty PL, Spormann AM. TITLE Molecular identification of the catabolic vinyl chloride reductase from Dehalococcoides sp. strain VS and its environmental distribution. JOURNAL Appl Environ Microbiol 70:4880-8 (2004) DOI:10.1128/AEM.70.8.4880-4888.2004 REFERENCE PMID:16957242 AUTHORS Lee PK, Johnson DR, Holmes VF, He J, Alvarez-Cohen L. TITLE Reductive dehalogenase gene expression as a biomarker for physiological activity of Dehalococcoides spp. JOURNAL Appl Environ Microbiol 72:6161-8 (2006) DOI:10.1128/AEM.01070-06 REFERENCE PMID:15865156 AUTHORS Torz M, Beschkov V TITLE Biodegradation of monochloroacetic acid used as a sole carbon and energy source by Xanthobacter autotrophicus GJ10 strain in batch and continuous culture. JOURNAL Biodegradation 16:423-33 (2005) DOI:10.1007/s10532-004-3614-8 REFERENCE PMID:10347028 AUTHORS Hage JC, Hartmans S TITLE Monooxygenase-mediated 1,2-dichloroethane degradation by Pseudomonas sp. strain DCA1. JOURNAL Appl Environ Microbiol 65:2466-70 (1999) DOI:10.1128/AEM.65.6.2466-2470.1999 REFERENCE PMID:9687453 AUTHORS Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB. TITLE Degradation of 1,3-dichloropropene by pseudomonas cichorii 170. JOURNAL Appl Environ Microbiol 64:2931-6 (1998) DOI:10.1128/AEM.64.8.2931-2936.1998 REFERENCE PMID:12411705 AUTHORS Sun B, Griffin BM, Ayala-del-Rio HL, Hashsham SA, Tiedje JM TITLE Microbial dehalorespiration with 1,1,1-trichloroethane. JOURNAL Science 298:1023-5 (2002) DOI:10.1126/science.1074675 REFERENCE PMID:11999413 AUTHORS Hashimoto A, Iwasaki K, Nakasugi N, Nakajima M, Yagi O TITLE Degradation pathways of trichloroethylene and 1,1,1-trichloroethane by Mycobacterium sp. TA27. JOURNAL Biosci Biotechnol Biochem 66:385-90 (2002) DOI:10.1271/bbb.66.385 REFERENCE PMID:1768109 AUTHORS Newman LM, Wackett LP TITLE Fate of 2,2,2-trichloroacetaldehyde (chloral hydrate) produced during trichloroethylene oxidation by methanotrophs. JOURNAL Appl Environ Microbiol 57:2399-402 (1991) DOI:10.1128/AEM.57.8.2399-2402.1991 REFERENCE PMID:8981984 AUTHORS Newman LM, Wackett LP TITLE Trichloroethylene oxidation by purified toluene 2-monooxygenase: products, kinetics, and turnover-dependent inactivation. JOURNAL J Bacteriol 179:90-6 (1997) DOI:10.1128/JB.179.1.90-96.1997 REL_PATHWAY ko00620 Pyruvate metabolism ko00630 Glyoxylate and dicarboxylate metabolism ko00680 Methane metabolism ///