ENTRY ko00620 Pathway NAME Pyruvate metabolism CLASS Metabolism; Carbohydrate metabolism PATHWAY_MAP ko00620 Pyruvate metabolism MODULE M00168 CAM (Crassulacean acid metabolism), dark [PATH:ko00620] M00169 CAM (Crassulacean acid metabolism), light [PATH:ko00620] M00172 C4-dicarboxylic acid cycle, NADP - malic enzyme type [PATH:ko00620] M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ko00620] M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ko00620] DBLINKS GO: 0006090 ORTHOLOGY K01895 acetyl-CoA synthetase [EC:6.2.1.1] K01913 acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2] K00169 pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] K00170 pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] K00172 pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] K00189 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] K00171 pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] K03737 pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] K00174 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] K00175 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] K00163 pyruvate dehydrogenase E1 component [EC:1.2.4.1] K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] K00162 pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] K00627 pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] K00382 dihydrolipoyl dehydrogenase [EC:1.8.1.4] K00656 formate C-acetyltransferase [EC:2.3.1.54] K00132 acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10] K04072 acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] K04073 acetaldehyde dehydrogenase [EC:1.2.1.10] K18366 acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87] K04021 aldehyde dehydrogenase K13951 alcohol dehydrogenase 1/7 [EC:1.1.1.1] K13980 alcohol dehydrogenase 4 [EC:1.1.1.1] K13952 alcohol dehydrogenase 6 [EC:1.1.1.1] K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] K13954 alcohol dehydrogenase [EC:1.1.1.1] K00001 alcohol dehydrogenase [EC:1.1.1.1] K00121 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] K18857 alcohol dehydrogenase class-P [EC:1.1.1.1] K00002 alcohol dehydrogenase (NADP+) [EC:1.1.1.2] K12957 alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183] K13979 alcohol dehydrogenase (NADP+) [EC:1.1.1.2] K14028 methanol dehydrogenase (cytochrome c) subunit 1 [EC:1.1.2.7] K14029 methanol dehydrogenase (cytochrome c) subunit 2 [EC:1.1.2.7] K00114 alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8] K04022 alcohol dehydrogenase K22473 alcohol dehydrogenase (quinone), dehydrogenase subunit [EC:1.1.5.5] K22474 alcohol dehydrogenase (quinone), cytochrome c subunit [EC:1.1.5.5] K00925 acetate kinase [EC:2.7.2.1] K00625 phosphate acetyltransferase [EC:2.3.1.8] K13788 phosphate acetyltransferase [EC:2.3.1.8] K15024 putative phosphotransacetylase [EC:2.3.1.8] K04020 phosphotransacetylase K00873 pyruvate kinase [EC:2.7.1.40] K12406 pyruvate kinase isozymes R/L [EC:2.7.1.40] K11262 acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K01946 acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] K01962 acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] K02160 acetyl-CoA carboxylase biotin carboxyl carrier protein K01961 acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] K01963 acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] K11263 acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14] K18472 acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] K01512 acylphosphatase [EC:3.6.1.7] K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] K14085 aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] K00149 aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] K00138 aldehyde dehydrogenase [EC:1.2.1.-] K01067 acetyl-CoA hydrolase [EC:3.1.2.1] K18118 succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] K01026 propionate CoA-transferase [EC:2.8.3.1] K01905 acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] K22224 acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] K24012 acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] K00158 pyruvate oxidase [EC:1.2.3.3] K00101 L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3] K26113 lactate dehydrogenase (NAD+,ferredoxin) subunit LctD [EC:1.1.1.436] K26114 lactate dehydrogenase (NAD+,ferredoxin) subunit LctC K26115 lactate dehydrogenase (NAD+,ferredoxin) subunit LctB K00016 L-lactate dehydrogenase [EC:1.1.1.27] K00156 pyruvate dehydrogenase (quinone) [EC:1.2.5.1] K00467 lactate 2-monooxygenase [EC:1.13.12.4] K03778 D-lactate dehydrogenase [EC:1.1.1.28] K03777 D-lactate dehydrogenase (quinone) [EC:1.1.5.12] K21836 D-lactate dehydrogenase (acceptor) [EC:1.1.99.6] K00102 D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] K18930 D-lactate dehydrogenase K21618 (R)-2-hydroxyglutarate---pyruvate transhydrogenase [EC:1.1.99.40] K17741 NADPH-dependent methylglyoxal reductase [EC:1.1.1.283] K23257 methylglyoxal/glyoxal reductase [EC:1.1.1.283 1.1.1.-] K07248 lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21] K19266 lactaldehyde dehydrogenase [EC:1.2.1.22] K01759 lactoylglutathione lyase [EC:4.4.1.5] K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6] K05523 D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124] K18881 D-lactate dehydratase [EC:4.2.1.130] K22211 D-lactate dehydratase [EC:4.2.1.130] K22373 lactate racemase [EC:5.1.2.1] K00049 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] K12972 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] K00090 glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215] K00027 malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] K00028 malate dehydrogenase (decarboxylating) [EC:1.1.1.39] K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] K01571 oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] K20509 carboxybiotin decarboxylase [EC:7.2.4.1] K01573 oxaloacetate decarboxylase (Na+ extruding) subunit gamma K01003 oxaloacetate decarboxylase [EC:4.1.1.112] K01958 pyruvate carboxylase [EC:6.4.1.1] K01959 pyruvate carboxylase subunit A [EC:6.4.1.1] K01960 pyruvate carboxylase subunit B [EC:6.4.1.1] K00025 malate dehydrogenase [EC:1.1.1.37] K00026 malate dehydrogenase [EC:1.1.1.37] K00024 malate dehydrogenase [EC:1.1.1.37] K00051 malate dehydrogenase (NADP+) [EC:1.1.1.82] K00116 malate dehydrogenase (quinone) [EC:1.1.5.4] K01676 fumarate hydratase, class I [EC:4.2.1.2] K01677 fumarate hydratase subunit alpha [EC:4.2.1.2] K01678 fumarate hydratase subunit beta [EC:4.2.1.2] K01679 fumarate hydratase, class II [EC:4.2.1.2] K01675 fumarate hydratase D [EC:4.2.1.2] K01774 fumarate hydratase E [EC:4.2.1.2] K00244 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] K00245 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] K00246 succinate dehydrogenase subunit C K00247 succinate dehydrogenase subunit D K00233 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12] K25995 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12] K25996 succinate dehydrogenase subunit C K26318 fumarate reductase (cytochrome) [EC:1.3.2.4] K22212 malolactic enzyme [EC:4.1.1.101] K01595 phosphoenolpyruvate carboxylase [EC:4.1.1.31] K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] K20370 phosphoenolpyruvate carboxykinase (diphosphate) [EC:4.1.1.38] K01610 phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] K01006 pyruvate, orthophosphate dikinase [EC:2.7.9.1] K01007 pyruvate, water dikinase [EC:2.7.9.2] K01638 malate synthase [EC:2.3.3.9] K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] K01649 2-isopropylmalate synthase [EC:2.3.3.13] K01655 homocitrate synthase [EC:2.3.3.14] K02594 homocitrate synthase NifV [EC:2.3.3.14] K10977 methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] COMPOUND C00022 Pyruvate C00024 Acetyl-CoA C00033 Acetate C00036 Oxaloacetate C00042 Succinate C00058 Formate C00068 Thiamin diphosphate C00074 Phosphoenolpyruvate C00083 Malonyl-CoA C00084 Acetaldehyde C00122 Fumarate C00149 (S)-Malate C00186 (S)-Lactate C00227 Acetyl phosphate C00256 (R)-Lactate C00332 Acetoacetyl-CoA C00424 (S)-Lactaldehyde C00469 Ethanol C00546 Methylglyoxal C00937 (R)-Lactaldehyde C01251 (R)-2-Hydroxybutane-1,2,4-tricarboxylate C02488 (R)-2-Ethylmalate C02504 alpha-Isopropylmalate C03248 Acetylenedicarboxylate C03451 (R)-S-Lactoylglutathione C03981 2-Hydroxyethylenedicarboxylate C05125 2-(alpha-Hydroxyethyl)thiamine diphosphate C05993 Acetyl adenylate C05994 2-Propylmalate C15972 Enzyme N6-(lipoyl)lysine C15973 Enzyme N6-(dihydrolipoyl)lysine C16255 [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine REFERENCE AUTHORS Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds). TITLE [Cellular Functions and Metabolic Maps] (In Japanese) JOURNAL Tokyo Kagaku Dojin (1997) REL_PATHWAY ko00010 Glycolysis / Gluconeogenesis ko00020 Citrate cycle (TCA cycle) ko00061 Fatty acid biosynthesis ko00250 Alanine, aspartate and glutamate metabolism ko00260 Glycine, serine and threonine metabolism ko00290 Valine, leucine and isoleucine biosynthesis ko00300 Lysine biosynthesis ko00522 Biosynthesis of 12-, 14- and 16-membered macrolides ko00630 Glyoxylate and dicarboxylate metabolism ko00640 Propanoate metabolism ko00650 Butanoate metabolism ko00760 Nicotinate and nicotinamide metabolism ko01056 Biosynthesis of type II polyketide backbone ko01059 Biosynthesis of enediyne antibiotics ///