ENTRY ko00523 Pathway NAME Polyketide sugar unit biosynthesis CLASS Metabolism; Metabolism of terpenoids and polyketides PATHWAY_MAP ko00523 Polyketide sugar unit biosynthesis MODULE M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:ko00523] M00794 dTDP-6-deoxy-D-allose biosynthesis [PATH:ko00523] M00795 dTDP-beta-L-noviose biosynthesis [PATH:ko00523] M00796 dTDP-D-mycaminose biosynthesis [PATH:ko00523] M00797 dTDP-D-desosamine biosynthesis [PATH:ko00523] M00798 dTDP-L-mycarose biosynthesis [PATH:ko00523] M00799 dTDP-L-oleandrose biosynthesis [PATH:ko00523] M00800 dTDP-L-megosamine biosynthesis [PATH:ko00523] M00801 dTDP-L-olivose biosynthesis [PATH:ko00523] M00802 dTDP-D-forosamine biosynthesis [PATH:ko00523] M00803 dTDP-D-angolosamine biosynthesis [PATH:ko00523] ORTHOLOGY K00067 rfbD, rmlD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] K00973 rfbA, rmlA, rffH; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] K01710 rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] K01790 rfbC, rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] K12451 UER1; 3,5-epimerase/4-reductase [EC:5.1.3.- 1.1.1.-] K12710 novU; C-methyltransferase [EC:2.1.1.-] K13306 fcd; dTDP-4-dehydro-6-deoxyglucose reductase [EC:1.1.1.266] K13307 tylMI; dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.235] K13308 desI, eryCIV; dTDP-4-amino-4,6-dideoxy-D-glucose transaminase [EC:2.6.1.33] K13309 desII, eryCV; dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase [EC:4.3.1.30] K13310 desV, eryCI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase [EC:2.6.1.106] K13311 desVI, eryCVI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.234] K13312 tylJ, gerF; dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase [EC:5.1.3.27] K13313 tylD, gerKI, mydI; dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase [EC:1.1.1.364] K13315 eryBII, tylCII, tylC1, calS12, atmS12; NDP-hexose C3-ketoreductase / dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene 2,3-reductase [EC:1.1.1.-] K13316 tylCVII, tylK; NDP-hexose 5-epimerase [EC:5.1.3.-] K13317 eryBIII, tylCIII, tylC3; NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase [EC:2.1.1.-] K13318 eryBIV, tylCIV, tylC2; dTDP-4-keto-6-deoxy-L-hexose 4-reductase [EC:1.1.1.-] K13319 oleU; 4-ketoreductase K13322 megDV; dTDP-4-keto-6-deoxyhexose 4-ketoreductase K13326 megDIII; dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.- 2.1.1.234] K13327 spnN, oleW; dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase [EC:1.1.1.384] K13328 spnQ; dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase [EC:4.2.1.164] K13329 spnR; dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase [EC:2.6.1.110] K13330 spnS; dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase [EC:2.1.1.324] K13332 angMI; N,N-dimethyltransferase K16435 evaA, eryBVI, tylCVI, tylX3, staJ; dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159] K16436 evaB, megDII, angB, staI; dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose/dTDP-2,6-dideoxy-D-kanosamine transaminase [EC:2.6.1.- 2.6.1.106] K16438 evaD, eryBVII, aveBV, megDIV, staE; 5-epimerase [EC:5.1.3.-] K17625 novS; dTDP-4-keto-6-deoxyhexose reductase [EC:1.1.1.-] K17947 wbiB; dTDP-L-rhamnose 4-epimerase [EC:5.1.3.25] K19180 tll; dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) [EC:1.1.1.339] K19652 tal; dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+] [EC:1.1.1.344] K19853 tyl1a; TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase [EC:5.3.2.4] K19854 tylB; dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase [EC:2.6.1.89] K19855 novW; dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase [EC:5.1.3.27] K19856 aveBVII, avrH; 3-O-methyltransferase [EC:2.1.1.-] K19857 aveBIV, avrE; dTDP-4-keto-6-deoxy-L-hexose 4-reductase K19858 oleL; dTDP-4-oxo-2,6-dideoxy-D-glucose 3,5-epimerase [EC:5.1.3.-] K19859 ang14; dTDP-4-keto-6-deoxyhexose reductase K20678 fcf2; dTDP-fucopyranose mutase [EC:5.4.99.59] K20679 fdtA; TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase [EC:5.3.2.3] K20680 fdtB; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase [EC:2.6.1.90] K20681 fdtC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197] K20682 ravNMT; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase [EC:2.1.1.236] K21325 calS11; dTDP-rhamnose C3-O-methyltransferase [EC:2.1.1.-] K21326 sgcA4; aminotransferase K21327 sgcA5; N-methyltransferase [EC:2.1.1.-] K21328 calS13, atmS13; dTDP-4-amino-4,6-dideoxy-D-glucose/dTDP-4-amino-2,4-dideoxy-beta-L-xylose transaminase [EC:2.6.1.33 2.6.1.-] K21329 calE10; aminosugar N-oxygenase [EC:1.14.15.-] K21330 calS4; C-S lyase K21331 calS8, atmS8; dTDP-alpha-D-glucose dehydrogenase [EC:1.1.1.-] K21332 calS9, atmS9; dTDP-alpha-D-glucuronic acid decarboxylase [EC:1.1.1.-] K21333 calS14, atmS14; dTDP-4-oxo-alpha-D-xylose 2,3-dehydratase [EC:4.2.1.-] K21335 calS10, atmS10; dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase [EC:2.1.1.-] K21336 mdpA4; C-methyltransferase [EC:2.1.1.-] K21337 mdpA5; aminotransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase K23987 rfbCD, rmlCD; dTDP-4-dehydrorhamnose 3,5-epimerase/reductase COMPOUND C00103 D-Glucose 1-phosphate C00688 dTDP-4-dehydro-beta-L-rhamnose C00842 dTDP-glucose C03187 dTDP-6-deoxy-beta-L-talose C03319 dTDP-L-rhamnose C04268 dTDP-4-amino-4,6-dideoxy-D-glucose C06017 dTDP-D-glucuronate C06620 dTDP-3,4-dioxo-2,6-dideoxy-D-glucose C07277 dTDP-D-fucose C11447 dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose C11460 dTDP-4-oxo-5-C-methyl-L-rhamnose C11461 dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose C11907 dTDP-4-oxo-6-deoxy-D-glucose C11908 dTDP-3-oxo-6-deoxy-D-glucose C11909 dTDP-3-oxo-4,6-dideoxy-D-glucose C11910 dTDP-3-amino-3,4,6-trideoxy-D-glucose C11911 dTDP-D-desosamine C11912 dTDP-6-deoxy-D-allose C11915 dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose C11916 dTDP-L-mycarose C11918 Maltol C11919 dTDP-L-megosamine C11920 dTDP-L-olivose C11921 dTDP-L-oleandrose C11922 dTDP-4-oxo-2,6-dideoxy-D-glucose C11925 dTDP-3-amino-3,6-dideoxy-D-glucose C11926 dTDP-4-oxo-6-deoxy-D-allose C11927 dTDP-4-oxo-2,6-dideoxy-L-mannose C11928 dTDP-4-oxo-2,6-dideoxy-D-allose C11933 dTDP-D-mycaminose C12318 dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose C12481 dTDP-5-dimethyl-L-lyxose C18029 dTDP-3-oxo-2,6-dideoxy-D-glucose C18030 dTDP-2,6-dideoxy-D-kanosamine C18031 dTDP-D-angolosamine C18032 dTDP-4-oxo-2,3,6-trideoxy-D-glucose C18033 dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose C18034 dTDP-D-forosamine C18035 dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose C19947 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose C19948 dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose C19960 dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose C20156 dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose C20682 dTDP-alpha-D-fucofuranose C21071 dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose C21073 dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose C21074 dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose C21348 dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose C21349 dTDP-4-deoxy-4-thio-alpha-D-digitoxose C21350 dTDP-3-O-methyl-beta-L-rhamnose C21351 dTDP-4-oxo-alpha-D-xylose C21352 dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene C21353 dTDP-4-oxo-2-deoxy-beta-L-xylose C21354 dTDP-4-amino-2,4-dideoxy-beta-L-xylose C21355 dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose C21356 dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose C21362 dTDP-3-methyl-4-oxo-alpha-D-ribopyranose C21363 dTDP-madurosamine REFERENCE PMID:11336289 AUTHORS Rawlings BJ. 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JOURNAL Proteins 83:1547-54 (2015) DOI:10.1002/prot.24844 REL_PATHWAY ko00401 Novobiocin biosynthesis ko00404 Staurosporine biosynthesis ko00520 Amino sugar and nucleotide sugar metabolism ko00521 Streptomycin biosynthesis ko00522 Biosynthesis of 12-, 14- and 16-membered macrolides ko01059 Biosynthesis of enediyne antibiotics ///