ENTRY ko00460 Pathway NAME Cyanoamino acid metabolism CLASS Metabolism; Metabolism of other amino acids PATHWAY_MAP ko00460 Cyanoamino acid metabolism MODULE M00369 Cyanogenic glycoside biosynthesis, tyrosine => dhurrin [PATH:ko00460] DBLINKS GO: 0033052 0019756 ORTHOLOGY K13027 tyrosine N-monooxygenase [EC:1.14.14.36] K13029 4-hydroxyphenylacetaldehyde oxime monooxygenase [EC:1.14.14.37] K13030 cyanohydrin beta-glucosyltransferase [EC:2.4.1.85] K01188 beta-glucosidase [EC:3.2.1.21] K05349 beta-glucosidase [EC:3.2.1.21] K05350 beta-glucosidase [EC:3.2.1.21] K08249 hydroxymandelonitrile lyase [EC:4.1.2.11] K14984 isoleucine N-monooxygenase [EC:1.14.14.39] K13401 valine N-monooxygenase [EC:1.14.14.38] K16265 (E)-2-methylbutanal oxime monooxygenase [EC:1.14.14.41] K16266 cyanohydrin UDP-glucosyltransferase [EC:2.4.1.-] K14577 aliphatic (R)-hydroxynitrile lyase [EC:4.1.2.46] K13033 (S)-hydroxynitrile lyase [EC:4.1.2.47] K12153 phenylalanine N-monooxygenase [EC:1.14.14.40] K00495 phenylacetaldehyde oxime monooxygenase [EC:1.14.14.44] K10566 phenylacetaldoxime dehydratase [EC:4.8.1.4] K22706 (R)-mandelonitrile beta-glucosyltransferase [EC:2.4.1.354] K13031 amygdalin beta-glucosidase [EC:3.2.1.117] K13032 prunasin beta-glucosidase [EC:3.2.1.118] K08248 (R)-mandelonitrile lyase [EC:4.1.2.10] K20802 (R)-mandelonitrile lyase [EC:4.1.2.10] K01501 nitrilase [EC:3.5.5.1] K13034 L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9] K00681 gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] K18592 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] K13035 beta-cyano-L-alanine hydratase/nitrilase [EC:3.5.5.4 4.2.1.65] K01424 L-asparaginase [EC:3.5.1.1] K13051 L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] K01914 aspartate--ammonia ligase [EC:6.3.1.1] K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] K10814 hydrogen cyanide synthase HcnA [EC:1.4.99.5] K10815 hydrogen cyanide synthase HcnB [EC:1.4.99.5] K10816 hydrogen cyanide synthase HcnC [EC:1.4.99.5] K18282 cyanide dihydratase [EC:3.5.5.-] K10675 cyanide hydratase [EC:4.2.1.66] K01455 formamidase [EC:3.5.1.49] COMPOUND C00014 Ammonia C00037 Glycine C00049 L-Aspartate C00065 L-Serine C00079 L-Phenylalanine C00082 L-Tyrosine C00097 L-Cysteine C00152 L-Asparagine C00183 L-Valine C00302 Glutamate C00407 L-Isoleucine C00488 Formamide C00561 Mandelonitrile C00844 Prunasin C01326 Hydrogen cyanide C01401 Alanine C01594 Linamarin C02512 3-Cyano-L-alanine C02659 Acetone cyanohydrin C03004 N-Hydroxy-L-tyrosine C03219 (E)-2-Methylpropanal oxime C03742 (S)-4-Hydroxymandelonitrile C04350 (E)-4-Hydroxyphenylacetaldehyde oxime C05143 Dhurrin C05670 3-Aminopropiononitrile C05711 gamma-Glutamyl-beta-cyanoalanine C05714 alpha-Aminopropiononitrile C05715 gamma-Amino-gamma-cyanobutanoate C06114 gamma-Glutamyl-beta-aminopropiononitrile C08325 Amygdalin C08334 Lotaustralin C15503 N,N-Dihydroxy-L-tyrosine C16074 Phenylacetonitrile C16075 (Z)-Phenylacetaldehyde oxime C18796 (2R)-2-Hydroxy-2-methylbutanenitrile C19491 (E)-2-Methylbutanal oxime C19712 N-Hydroxy-L-phenylalanine C19714 (E)-Phenylacetaldoxime C19715 N,N-Dihydroxy-L-phenylalanine C20310 N-Hydroxy-L-isoleucine C20311 N,N-Dihydroxy-L-isoleucine C20312 (Z)-2-Methylbutanal oxime C20313 N-Hydroxy-L-valine C20314 N,N-Dihydroxy-L-valine C20315 (Z)-2-Methylpropanal oxime REFERENCE PMID:11575729 AUTHORS Maruyama A, Saito K, Ishizawa K TITLE Beta-cyanoalanine synthase and cysteine synthase from potato: molecular cloning, biochemical characterization, and spatial and hormonal regulation. JOURNAL Plant Mol Biol 46:749-60 (2001) DOI:10.1023/A:1011629703784 REFERENCE PMID:10636899 AUTHORS Andersen MD, Busk PK, Svendsen I, Moller BL TITLE Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin. Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes. JOURNAL J Biol Chem 275:1966-75 (2000) DOI:10.1074/jbc.275.3.1966 REFERENCE AUTHORS Hickel A, Hasslacher M, Griengl H. TITLE Hydroxynitrile lyases: Functions and properties JOURNAL Physiol Plant 98:891-898 (1996) DOI:10.1111/j.1399-3054.1996.tb06700.x REL_PATHWAY ko00250 Alanine, aspartate and glutamate metabolism ko00260 Glycine, serine and threonine metabolism ko00270 Cysteine and methionine metabolism ko00290 Valine, leucine and isoleucine biosynthesis ko00350 Tyrosine metabolism ko00360 Phenylalanine metabolism ko00410 beta-Alanine metabolism ko00450 Selenocompound metabolism ko00470 D-Amino acid metabolism ko00480 Glutathione metabolism ko00910 Nitrogen metabolism ///