ENTRY ko00340 Pathway NAME Histidine metabolism CLASS Metabolism; Amino acid metabolism PATHWAY_MAP ko00340 Histidine metabolism MODULE M00026 Histidine biosynthesis, PRPP => histidine [PATH:ko00340] M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:ko00340] DRUG D02922 Amodiaquine (USP/INN) DBLINKS GO: 0006547 ORTHOLOGY K00765 ATP phosphoribosyltransferase [EC:2.4.2.17] K02502 ATP phosphoribosyltransferase regulatory subunit K01523 phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] K01496 phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] K11755 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] K14152 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23] K01814 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] K24017 phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24] K02501 imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] K02500 imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] K01663 imidazole glycerol-phosphate synthase [EC:4.3.2.10] K01693 imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] K01089 imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9] K05602 histidinol-phosphatase [EC:3.1.3.15] K04486 histidinol-phosphatase (PHP family) [EC:3.1.3.15] K18649 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15] K00013 histidinol dehydrogenase [EC:1.1.1.23] K01745 histidine ammonia-lyase [EC:4.3.1.3] K01712 urocanate hydratase [EC:4.2.1.49] K01468 imidazolonepropionase [EC:3.5.2.7] K01479 formiminoglutamase [EC:3.5.3.8] K00603 glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] K13990 glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4] K05603 formimidoylglutamate deiminase [EC:3.5.3.13] K01458 N-formylglutamate deformylase [EC:3.5.1.68] K17363 urocanate reductase [EC:1.3.99.33] K01590 histidine decarboxylase [EC:4.1.1.22] K11182 diamine oxidase [EC:1.4.3.22] K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] K14085 aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] K00149 aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] K01437 aspartoacylase [EC:3.5.1.15] K00546 histamine N-methyltransferase [EC:2.1.1.8] K00274 monoamine oxidase [EC:1.4.3.4] K00129 aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] K14755 carnosine synthase [EC:6.3.2.11] K19787 carnosine N-methyltransferase [EC:2.1.1.22] K22437 carnosine N-methyltransferase [EC:2.1.1.22] K08660 cytosolic nonspecific dipeptidase [EC:3.4.13.18] K05604 beta-Ala-His dipeptidase [EC:3.4.13.20] K20246 L-histidine Nalpha-methyltransferase / hercynylcysteine S-oxide synthase [EC:2.1.1.44 1.21.3.10] K18911 L-histidine Nalpha-methyltransferase [EC:2.1.1.44] K18912 gamma-glutamyl hercynylcysteine S-oxide synthase [EC:1.14.99.50] K07008 gamma-glutamyl hercynylcysteine S-oxide hydrolase [EC:3.5.1.118] K20247 hercynylcysteine S-oxide lyase [EC:4.4.1.36] K18913 hercynylcysteine S-oxide lyase [EC:4.4.1.36] COMPOUND C00025 L-Glutamate C00026 2-Oxoglutarate C00049 L-Aspartate C00119 5-Phospho-alpha-D-ribose 1-diphosphate C00135 L-Histidine C00386 Carnosine C00388 Histamine C00439 N-Formimino-L-glutamate C00785 Urocanate C00860 L-Histidinol C01044 N-Formyl-L-aspartate C01045 N-Formyl-L-glutamate C01100 L-Histidinol phosphate C01152 N(pi)-Methyl-L-histidine C01262 beta-Alanyl-N(pi)-methyl-L-histidine C01267 3-(Imidazol-4-yl)-2-oxopropyl phosphate C01929 L-Histidinal C02739 1-(5-Phospho-D-ribosyl)-ATP C02741 Phosphoribosyl-AMP C02835 Imidazole-4-acetate C03277 Imidazol-5-yl-pyruvate C03409 N-Formimino-L-aspartate C03680 4-Imidazolone-5-propanoate C04437 1-(5-Phosphoribosyl)imidazole-4-acetate C04666 D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate C04677 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide C04896 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide C04916 N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide C05127 N-Methylhistamine C05130 Imidazole-4-acetaldehyde C05131 (1-Ribosylimidazole)-4-acetate C05133 4-Imidazolone-5-acetate C05135 4-(beta-Acetylaminoethyl)imidazole C05565 Hydantoin-5-propionate C05568 Imidazole lactate C05570 Ergothioneine C05571 Thiourocanic acid C05572 4-Oxoglutaramate C05575 Hercynine C05827 Methylimidazole acetaldehyde C05828 Methylimidazoleacetic acid C05829 N-Carbamyl-L-glutamate C16673 Isoglutamine C16674 Formylisoglutamine C20522 Dihydrourocanate C20994 S-(Hercyn-2-yl)-L-cysteine S-oxide C20995 gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide REL_PATHWAY ko00030 Pentose phosphate pathway ko00230 Purine metabolism ko00250 Alanine, aspartate and glutamate metabolism ///