ENTRY ko00250 Pathway NAME Alanine, aspartate and glutamate metabolism CLASS Metabolism; Amino acid metabolism PATHWAY_MAP ko00250 Alanine, aspartate and glutamate metabolism MODULE M00027 GABA (gamma-Aminobutyrate) shunt [PATH:ko00250] M00740 Methylaspartate cycle [PATH:ko00250] DBLINKS GO: 0006522 0006531 0006536 ORTHOLOGY K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] K00811 aspartate aminotransferase, chloroplastic [EC:2.6.1.1] K00812 aspartate aminotransferase [EC:2.6.1.1] K00813 aspartate aminotransferase [EC:2.6.1.1] K11358 aspartate aminotransferase [EC:2.6.1.1] K03334 L-amino-acid oxidase [EC:1.4.3.2] K00278 L-aspartate oxidase [EC:1.4.3.16] K01779 aspartate racemase [EC:5.1.1.13] K00272 D-aspartate oxidase [EC:1.4.3.1] K01424 L-asparaginase [EC:3.5.1.1] K13051 L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] K05597 glutamin-(asparagin-)ase [EC:3.5.1.38] K01914 aspartate--ammonia ligase [EC:6.3.1.1] K01953 asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] K22457 asparagine---oxo-acid transaminase [EC:2.6.1.14] K13566 omega-amidase [EC:3.5.1.3] K09758 aspartate 4-decarboxylase [EC:4.1.1.12] K00814 alanine transaminase [EC:2.6.1.2] K14260 alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] K00830 alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51] K00827 alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40] K14272 glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44] K00259 alanine dehydrogenase [EC:1.4.1.1] K19244 alanine dehydrogenase [EC:1.4.1.1] K01744 aspartate ammonia-lyase [EC:4.3.1.1] K01940 argininosuccinate synthase [EC:6.3.4.5] K01755 argininosuccinate lyase [EC:4.3.2.1] K14681 argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1] K01939 adenylosuccinate synthase [EC:6.3.4.4] K01756 adenylosuccinate lyase [EC:4.3.2.2] K18309 aspartate N-acetyltransferase [EC:2.3.1.17] K18310 beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41] K18311 N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42] K14592 glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21] K01437 aspartoacylase [EC:3.5.1.15] K00609 aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] K00610 aspartate carbamoyltransferase regulatory subunit K00608 aspartate carbamoyltransferase [EC:2.1.3.2] K01580 glutamate decarboxylase [EC:4.1.1.15] K00823 4-aminobutyrate aminotransferase [EC:2.6.1.19] K14268 5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19] K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] K13524 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] K16871 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96] K00135 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] K00139 succinate-semialdehyde dehydrogenase [EC:1.2.1.24] K17761 succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24] K08324 succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24] K00264 glutamate synthase (NADH) [EC:1.4.1.14] K00265 glutamate synthase (NADPH) large chain [EC:1.4.1.13] K00266 glutamate synthase (NADPH) small chain [EC:1.4.1.13] K15371 glutamate dehydrogenase [EC:1.4.1.2] K00260 glutamate dehydrogenase [EC:1.4.1.2] K00261 glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] K00262 glutamate dehydrogenase (NADP+) [EC:1.4.1.4] K00294 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] K13821 RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] K01915 glutamine synthetase [EC:6.3.1.2] K11540 carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] K11541 carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2] K01954 carbamoyl-phosphate synthase [EC:6.3.5.5] K01955 carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] K01956 carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] K01425 glutaminase [EC:3.5.1.2] K23265 phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16] K08590 2-oxoglutaramate amidase [EC:3.5.1.111] K00820 glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] K00764 amidophosphoribosyltransferase [EC:2.4.2.14] COMPOUND C00014 Ammonia C00022 Pyruvate C00025 L-Glutamate C00026 2-Oxoglutarate C00036 Oxaloacetate C00041 L-Alanine C00042 Succinate C00049 L-Aspartate C00064 L-Glutamine C00122 Fumarate C00152 L-Asparagine C00158 Citrate C00169 Carbamoyl phosphate C00232 Succinate semialdehyde C00334 4-Aminobutanoate C00352 D-Glucosamine 6-phosphate C00402 D-Aspartate C00438 N-Carbamoyl-L-aspartate C00940 2-Oxoglutaramate C01042 N-Acetyl-L-aspartate C02362 2-Oxosuccinamate C03090 5-Phosphoribosylamine C03406 N-(L-Arginino)succinate C03794 N6-(1,2-Dicarboxyethyl)-AMP C03912 (S)-1-Pyrroline-5-carboxylate C12270 N-Acetylaspartylglutamate C20775 beta-Citryl-L-glutamate C20776 N-Acetylaspartylglutamylglutamate REFERENCE AUTHORS Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds). TITLE [Cellular Functions and Metabolic Maps] (In Japanese) JOURNAL Tokyo Kagaku Dojin (1997) REFERENCE PMID:9687539 AUTHORS Wu G TITLE Intestinal mucosal amino acid catabolism. JOURNAL J Nutr 128:1249-52 (1998) DOI:10.1093/jn/128.8.1249 REL_PATHWAY ko00010 Glycolysis / Gluconeogenesis ko00020 Citrate cycle (TCA cycle) ko00220 Arginine biosynthesis ko00230 Purine metabolism ko00240 Pyrimidine metabolism ko00260 Glycine, serine and threonine metabolism ko00261 Monobactam biosynthesis ko00300 Lysine biosynthesis ko00330 Arginine and proline metabolism ko00340 Histidine metabolism ko00410 beta-Alanine metabolism ko00460 Cyanoamino acid metabolism ko00470 D-Amino acid metabolism ko00480 Glutathione metabolism ko00520 Amino sugar and nucleotide sugar metabolism ko00620 Pyruvate metabolism ko00630 Glyoxylate and dicarboxylate metabolism ko00650 Butanoate metabolism ko00660 C5-Branched dibasic acid metabolism ko00760 Nicotinate and nicotinamide metabolism ko00770 Pantothenate and CoA biosynthesis ko00860 Porphyrin metabolism ko00910 Nitrogen metabolism ///