ENTRY       10458             CDS       T01001
SYMBOL      BAIAP2, BAP2, FLAF3, IRSP53, WAML
NAME        (RefSeq) BAR/IMD domain containing adaptor protein 2
ORTHOLOGY   K05627  BAI1-associated protein 2
ORGANISM    hsa  Homo sapiens (human)
PATHWAY     hsa04520  Adherens junction
            hsa04810  Regulation of actin cytoskeleton
            hsa05130  Pathogenic Escherichia coli infection
            hsa05135  Yersinia infection
NETWORK     nt06180  Pathogenic Escherichia coli
  ELEMENT   N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
BRITE       KEGG Orthology (KO) [BR:hsa00001]
             09140 Cellular Processes
              09144 Cellular community - eukaryotes
               04520 Adherens junction
                10458 (BAIAP2)
              09142 Cell motility
               04810 Regulation of actin cytoskeleton
                10458 (BAIAP2)
             09160 Human Diseases
              09171 Infectious disease: bacterial
               05130 Pathogenic Escherichia coli infection
                10458 (BAIAP2)
               05135 Yersinia infection
                10458 (BAIAP2)
             09180 Brite Hierarchies
              09182 Protein families: genetic information processing
               04131 Membrane trafficking [BR:hsa04131]
                10458 (BAIAP2)
            Membrane trafficking [BR:hsa04131]
             Endocytosis
              Bin/Amphiphysin/Rvs (BAR) family proteins
               I-BAR proteins
                10458 (BAIAP2)
POSITION    17:81035151..81117434
MOTIF       Pfam: IMD SH3_2 SH3_9 SH3_1 BAR Peptidase_Mx1 BAR_3
DBLINKS     NCBI-GeneID: 10458
            NCBI-ProteinID: NP_059345
            OMIM: 605475
            HGNC: 947
            Ensembl: ENSG00000175866
            UniProt: Q9UQB8
STRUCTURE   PDB
AASEQ       552
            MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
            ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
            KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
            DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
            VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
            GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
            LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
            TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
            QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRCDLSAQGPEGRE
            HGDGSARTLAGR
NTSEQ       1659
            atgtctctgtctcgctcagaggagatgcaccggctcacggaaaatgtctataagaccatc
            atggagcagttcaaccctagcctccggaacttcatcgccatggggaagaattacgagaag
            gcactggcaggtgtgacgtatgcagccaaaggctactttgacgccctggtgaagatgggg
            gagctggccagcgagagccagggctccaaagaactcggagacgttctcttccagatggct
            gaagtccacaggcagatccagaatcagctggaagaaatgctgaagtcttttcacaacgag
            ctgcttacgcagctggagcagaaggtggagctggactccaggtatctgagtgctgcgctg
            aagaaataccagactgagcaaaggagcaaaggcgacgccctggacaagtgtcaggctgag
            ctgaagaagcttcggaagaagagccagggcagcaagaatcctcagaagtactcggacaag
            gagctgcagtacatcgacgccatcagcaacaagcagggcgagctggagaattacgtgtcc
            gacggctacaagaccgcactgacagaggagcgcaggcgcttctgcttcctggtggagaag
            cagtgcgccgtggccaagaactccgcggcctaccactccaagggcaaggagctgctggcg
            cagaagctgccgctgtggcaacaggcctgtgccgaccccagcaagatcccggagcgcgcg
            gtgcagctcatgcagcaggtggccagcaacggcgccaccctccccagcgccctgtcggcc
            tccaagtccaacctggtcatttccgaccccattccgggggccaagcccctgccggtgccc
            cccgagctggcaccgttcgtggggcggatgtctgcccaggagagcacacccatcatgaac
            ggcgtcacaggcccggatggcgaggactacagcccgtgggctgaccgcaaggctgcccag
            cccaaatccctgtctcctccgcagtctcagagcaagctcagcgactcctactccaacaca
            ctccccgtgcgcaagagcgtgaccccaaaaaacagctatgccaccaccgagaacaagact
            ctgcctcgctcgagctccatggcagccggcctggagcgcaatggccgtatgcgggtgaag
            gccatcttctcccacgctgctggggacaacagcaccctcctgagcttcaaggagggtgac
            ctcattaccctgctggtgcctgaggcccgcgatggctggcactacggagagagtgagaag
            accaagatgcggggctggtttcccttctcctacacccgggtcttggacagcgatggcagt
            gacaggctgcacatgagcctgcagcaagggaagagcagcagcacgggcaacctcctggac
            aaggacgacctggccatcccaccccccgattacggcgccgcctcccgggccttccccgcc
            cagacggccagcggcttcaagcagaggccctacagtgtggccgtgcccgccttctcccag
            ggcctggatgactatggagcgcggtccatgagcaggaatccctttgcccacgtccagctg
            aagccgacagtgaccaacgacaggtgtgatctgtccgcccaagggccagaaggccgggag
            cacggggatgggagcgcccgcaccctggctggaagatga
///