ENTRY       T00588            Complete  Genome
ORG_CODE    saw
NAME        Staphylococcus aureus subsp. aureus Mu3, methicillin-resistant, heterogeneous vancomycin-intermediate resistance
ANNOTATION  yes
TAXONOMY    TAX:418127
  LINEAGE   Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
BRITE       KEGG organisms [BR:br08601]
            KEGG organisms in the NCBI taxonomy [BR:br08610]
            KEGG organisms in taxonomic ranks [BR:br08611]
DATA_SOURCE GenBank (Assembly: GCA_000010445.1 Complete Genome)
            BioProject: 18509
KEYWORDS    Human pathogen
DISEASE     H00330  Methicillin-resistant Staphylococcal aureus (MRSA) infection
            H00331  Vancomycin-resistant Staphylococcal aureus (VRSA) infection
COMMENT     Isolated from the purulent sputum of a Japanese patient with pneumonia after surgery who had failed vancomycin therapy.
CHROMOSOME  Circular
  SEQUENCE  GB:AP009324
  LENGTH    2880168
STATISTICS  Number of nucleotides:       2880168
            Number of protein genes:        2699
            Number of RNA genes:              77
CREATED     2007
REFERENCE   PMID:17954695
  AUTHORS   Neoh HM, Cui L, Yuzawa H, Takeuchi F, Matsuo M, Hiramatsu K.
  TITLE     Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance.
  JOURNAL   Antimicrob Agents Chemother 52:45-53 (2008)
            DOI:10.1128/AAC.00534-07
///